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4 results on '"Morales-Mena, Anabelle"'

1. A Large Set of Finnish Affected Sibling Pair Families With Type 2 Diabetes Suggests Susceptibility Loci on Chromosomes 6, 11, and 14

Author

Silander, Kaisa, Scott, Laura J., Valle, Timo T., Mohlke, Karen L., Stringham, Heather M., Wiles, Kerry R., Duren, William L., Doheny, Kimberly F., Pugh, Elizabeth W., Chines, Peter, Narisu, Narisu, White, Peggy P., Fingerlin, Tasha E., Jackson, Anne U., Li, Chun, Ghosh, Soumitra, Magnuson, Victoria L., Colby, Kimberly, Erdos, Michael R., Hill, Jason E., Hollstein, Pablo, Humphreys, Kathleen M., Kasad, Roshni A., Lambert, Jessica, Lazaridis, Konstantinos N., Lin, George, Morales-Mena, Anabelle, Patzkowski, Kristin, Pfahl, Carrie, Porter, Rachel, Rha, David, Segal, Leonid, Suh, Yong D., Tovar, Jason, Unni, Arun, Welch, Christian, Douglas, Julie A., Epstein, Michael P., Hauser, Elizabeth R., Hagopian, William, Buchanan, Thomas A., Watanabe, Richard M., Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., and Boehnke, Michael

Published
2004

2. The Finland--United States Investigation of Non--Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. II. An Autosomal Genome Scan for Diabetes-Related Quantitative-Trait Loci

Author

Watanabe, Richard M., Ghosh, Soumitra, Langefeld, Carl D., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Mohlke, Karen L., Silander, Kaisa, Ally, Delphine S., Chines, Peter, Blaschak-Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Balow, James Jr., Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales-Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Kohtamaki, Kimmo, Ehnholm, Christian, Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto-Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis, and Boehnke, Michael

Subjects
Genetic research -- Analysis, Human genetics -- Research, Genetic disorders -- Research, Diabetes -- Genetic aspects, Biological sciences
Published
2000

3. The Finland--United States Investigation of Non--Insulin-Dependent Diabetes Mellitus Genetics (FUSION) Study. I. An Autosomal Genome Scan for Genes That Predispose to Type 2 Diabetes

Author

Ghosh, Soumitra, Watanabe, Richard M., Valle, Timo T., Hauser, Elizabeth R., Magnuson, Victoria L., Langefeld, Carl D., Ally, Delphine S., Mohlke, Karen L., Silander, Kaisa, Kohtamaki, Kimmo, Chines, Peter, Balow, James Jr., Birznieks, Gunther, Chang, Jennie, Eldridge, William, Erdos, Michael R., Karanjawala, Zarir E., Knapp, Julie I., Kudelko, Kristina, Martin, Colin, Morales-Mena, Anabelle, Musick, Anjene, Musick, Tiffany, Pfahl, Carrie, Porter, Rachel, Rayman, Joseph B., Rha, David, Segal, Leonid, Shapiro, Shane, Sharaf, Ravi, Shurtleff, Ben, So, Alistair, Tannenbaum, Joyce, Te, Catherine, Tovar, Jason, Unni, Arun, Welch, Christian, Whiten, Ray, Witt, Alyson, Blaschak-Harvan, Jillian, Douglas, Julie A., Duren, William L., Epstein, Michael P., Fingerlin, Tasha E., Kaleta, Hong Shi, Lange, Ethan M., Li, Chun, McEachin, Richard C., Stringham, Heather M., Trager, Edward, White, Peggy P., Eriksson, Johan, Toivanen, Liisa, Vidgren, Gabriele, Nylund, Stella J., Tuomilehto-Wolf, Eva, Ross, Edna H., Demirchyan, Elza, Hagopian, William A., Buchanan, Thomas A., Tuomilehto, Jaakko, Bergman, Richard N., Collins, Francis, and Boehnke, Michael

Subjects
Genetic research -- Analysis, Human genetics -- Research, Genetic disorders -- Research, Diabetes -- Genetic aspects, Biological sciences
Published
2000

4. Long-term outcomes of patients with primary angiitis of the central nervous system.

Author

Hajj-Ali RA, Saygin D, Ray E, Morales-Mena A, Messner W, Sundaram P, Jones S, and Calabrese LH

Subjects
Cerebral Angiography, Cognition Disorders etiology, Depressive Disorder etiology, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Neurologic Examination, Quality of Life, Cognition Disorders diagnosis, Depressive Disorder diagnosis, Vasculitis, Central Nervous System cerebrospinal fluid, Vasculitis, Central Nervous System complications, Vasculitis, Central Nervous System diagnosis
Abstract

Objectives: Primary angiitis of the central nervous system (PACNS) is a vasculitis confined to the brain and spinal cord, which often presents with severe cognitive and functional deficits. Despite progress in diagnosis, little is still known about long-term outcomes. Our aim was to evaluate long-term functional capabilities, quality of life, and depression, and to determine the effect of treatment duration on patient outcomes., Methods: We identified patients by ICD-9 codes for cerebral angiitis, and included them if they met two of the three following criteria: inflammatory cerebrospinal fluid (CSF), cerebral angiogram typical of vasculitis, or findings of vasculitis on pathologic examination of brain tissue. Disability was assessed by the Barthel Index, quality of life was assessed by EuroQol, and depression was assessed with Patient Health Questionnaire., Results: Seventy-eight patients met the inclusion criteria, of which 27 responded to the questionnaire (34.6%). Mean follow-up of those who responded was 5.5 years (± 4.7). Nineteen of 27 patients (70.4%) had mild disability; meanwhile, 5 (18.5%) had severe disability. Fourteen of 27 patients (51.9%) had no mobility problem, 18 (66.7%) had no problems with self-care, 15 (55.6%) had no problems with usual activities, 14 (51.9%) had no pain, and 8 (29.6%) had no anxiety. Approximately 70% of patients had minimal or no depression., Conclusions: This is the longest reported follow-up of patients with PACNS described in the literature to date. Most patients had mild long-term disability and minimal to no depression, which may be reflective of treatment advances.

Published
2019

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