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632 results on '"Moorman, Patricia G"'

1. Menopausal hormone therapy use and risk of ovarian cancer by race: the ovarian cancer in women of African ancestry consortium

Author

Petrick, Jessica L., Joslin, Charlotte E., Johnson, Courtney E., Camacho, T. Fabian, Peres, Lauren C., Bandera, Elisa V., Barnard, Mollie E., Beeghly, Alicia, Bethea, Traci N., Dempsey, Lauren F., Guertin, Kristin, Harris, Holly R., Moorman, Patricia G., Myers, Evan R., Ochs-Balcom, Heather M., Rosenow, Will, Setiawan, V. Wendy, Wu, Anna H., Schildkraut, Joellen M., and Rosenberg, Lynn

Published
2023
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2. Identification of novel epithelial ovarian cancer loci in women of African ancestry

Author

Manichaikul, Ani, Peres, Lauren C, Wang, Xin‐Qun, Barnard, Mollie E, Chyn, Deanna, Sheng, Xin, Du, Zhaohui, Tyrer, Jonathan, Dennis, Joseph, Schwartz, Ann G, Cote, Michele L, Peters, Edward, Moorman, Patricia G, Bondy, Melissa, Barnholtz‐Sloan, Jill S, Terry, Paul, Alberg, Anthony J, Bandera, Elisa V, Funkhouser, Ellen, Wu, Anna H, Pearce, Celeste Leigh, Pike, Malcom, Setiawan, Veronica Wendy, Haiman, Christopher A, Consortium, the African American Breast Cancer, Consortium, the African Ancestry Prostate Cancer, Palmer, Julie R, LeMarchand, Loic, Wilkens, Lynne R, Berchuck, Andrew, Doherty, Jennifer A, Modugno, Francesmary, Ness, Roberta, Moysich, Kirsten, Karlan, Beth Y, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Lawrenson, Kate, Gayther, Simon, Sellers, Thomas A, Pharoah, Paul, Schildkraut, Joellen M, and Consortium, the African American Cancer Epidemiology Study and the Ovarian Cancer Association

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biotechnology, Cancer, Prevention, Ovarian Cancer, Rare Diseases, Genetics, Clinical Research, 2.1 Biological and endogenous factors, Aetiology, Black or African American, Aldo-Keto Reductase Family 1 Member C3, Antigens, Neoplasm, Black People, Breast Neoplasms, Carcinoma, Ovarian Epithelial, Female, Follistatin, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Neoplasm Proteins, Polymorphism, Single Nucleotide, United States, White People, ovarian cancer, African ancestry, genome wide association study, gene expression, eQTLs, African American Breast Cancer Consortium, African Ancestry Prostate Cancer Consortium, African American Cancer Epidemiology Study (AACES) and the Ovarian Cancer Association Consortium, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

Women of African ancestry have lower incidence of epithelial ovarian cancer (EOC) yet worse survival compared to women of European ancestry. We conducted a genome-wide association study in African ancestry women with 755 EOC cases, including 537 high-grade serous ovarian carcinomas (HGSOC) and 1,235 controls. We identified four novel loci with suggestive evidence of association with EOC (p

Published
2020

3. Racial differences in the association of body mass index and ovarian cancer risk in the OCWAA Consortium

Author

Ochs-Balcom, Heather M., Johnson, Courtney, Guertin, Kristin A., Qin, Bo, Beeghly-Fadiel, Alicia, Camacho, Fabian, Bethea, Traci N., Dempsey, Lauren F., Rosenow, Will, Joslin, Charlotte E., Myers, Evan, Moorman, Patricia G., Harris, Holly R., Peres, Lauren C., Wendy Setiawan, V., Wu, Anna H., Rosenberg, Lynn, Schildkraut, Joellen M., and Bandera, Elisa V.

Published
2022
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4. Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

Author

Grant, Delores J, Manichaikul, Ani, Alberg, Anthony J, Bandera, Elisa V, Barnholtz‐Sloan, Jill, Bondy, Melissa, Cote, Michele L, Funkhouser, Ellen, Moorman, Patricia G, Peres, Lauren C, Peters, Edward S, Schwartz, Ann G, Terry, Paul D, Wang, Xin‐Qun, Keku, Temitope O, Hoyo, Cathrine, Berchuck, Andrew, Sandler, Dale P, Taylor, Jack A, O’Brien, Katie M, Edwards, Digna R Velez, Edwards, Todd L, Beeghly‐Fadiel, Alicia, Wentzensen, Nicolas, Pearce, Celeste Leigh, Wu, Anna H, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Rothstein, Joseph H, Modugno, Francesmary, Ness, Roberta, Moysich, Kirsten, Rossing, Mary Anne, Doherty, Jennifer A, Sellers, Thomas A, Permuth‐Way, Jennifer B, Monteiro, Alvaro N, Levine, Douglas A, Setiawan, Veronica Wendy, Haiman, Christopher A, LeMarchand, Loic, Wilkens, Lynne R, Karlan, Beth Y, Menon, Usha, Ramus, Susan, Gayther, Simon, Gentry‐Maharaj, Aleksandra, Terry, Kathryn L, Cramer, Daniel W, Goode, Ellen L, Larson, Melissa C, Kaufmann, Scott H, Cannioto, Rikki, Odunsi, Kunle, Etter, John L, Huang, Ruea‐Yea, Bernardini, Marcus Q, Tone, Alicia A, May, Taymaa, Goodman, Marc T, Thompson, Pamela J, Carney, Michael E, Tworoger, Shelley S, Poole, Elizabeth M, Lambrechts, Diether, Vergote, Ignace, Vanderstichele, Adriaan, Van Nieuwenhuysen, Els, Anton‐Culver, Hoda, Ziogas, Argyrios, Brenton, James D, Bjorge, Line, Salvensen, Helga B, Kiemeney, Lambertus A, Massuger, Leon FAG, Pejovic, Tanja, Bruegl, Amanda, Moffitt, Melissa, Cook, Linda, Le, Nhu D, Brooks‐Wilson, Angela, Kelemen, Linda E, Pharoah, Paul DP, Song, Honglin, Campbell, Ian, Eccles, Diana, DeFazio, Anna, Kennedy, Catherine J, and Schildkraut, Joellen M

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biotechnology, Nutrition, Rare Diseases, Clinical Research, Genetics, Ovarian Cancer, Prevention, Cancer, 2.1 Biological and endogenous factors, Aetiology, Black or African American, Bayes Theorem, Carcinoma, Ovarian Epithelial, ErbB Receptors, Female, Genetic Association Studies, Glucuronosyltransferase, Humans, Logistic Models, Middle Aged, Neoplasm Grading, Ovarian Neoplasms, Polymorphism, Single Nucleotide, Receptors, Calcitriol, Vitamin D, African ancestry risk, genetic association, ovarian cancer, vitamin D pathway, Biochemistry and Cell Biology, Oncology and carcinogenesis
Abstract

An association between genetic variants in the vitamin D receptor (VDR) gene and epithelial ovarian cancer (EOC) was previously reported in women of African ancestry (AA). We sought to examine associations between genetic variants in VDR and additional genes from vitamin D biosynthesis and pathway targets (EGFR, UGT1A, UGT2A1/2, UGT2B, CYP3A4/5, CYP2R1, CYP27B1, CYP24A1, CYP11A1, and GC). Genotyping was performed using the custom-designed 533,631 SNP Illumina OncoArray with imputation to the 1,000 Genomes Phase 3 v5 reference set in 755 EOC cases, including 537 high-grade serous (HGSOC), and 1,235 controls. All subjects are of African ancestry (AA). Logistic regression was performed to estimate odds ratios (OR) and 95% confidence intervals (CI). We further evaluated statistical significance of selected SNPs using the Bayesian False Discovery Probability (BFDP). A significant association with EOC was identified in the UGT2A1/2 region for the SNP rs10017134 (per allele OR = 1.4, 95% CI = 1.2-1.7, P = 1.2 × 10-6 , BFDP = 0.02); and an association with HGSOC was identified in the EGFR region for the SNP rs114972508 (per allele OR = 2.3, 95% CI = 1.6-3.4, P = 1.6 × 10-5 , BFDP = 0.29) and in the UGT2A1/2 region again for rs1017134 (per allele OR = 1.4, 95% CI = 1.2-1.7, P = 2.3 × 10-5 , BFDP = 0.23). Genetic variants in the EGFR and UGT2A1/2 may increase susceptibility of EOC in AA women. Future studies to validate these findings are warranted. Alterations in EGFR and UGT2A1/2 could perturb enzyme efficacy, proliferation in ovaries, impact and mark susceptibility to EOC.

Published
2019

5. Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

Author

Yang, Yaohua, Wu, Lang, Shu, Xiang, Lu, Yingchang, Shu, Xiao-Ou, Cai, Qiuyin, Beeghly-Fadiel, Alicia, Li, Bingshan, Ye, Fei, Berchuck, Andrew, Anton-Culver, Hoda, Banerjee, Susana, Benitez, Javier, Bjørge, Line, Brenton, James D, Butzow, Ralf, Campbell, Ian G, Chang-Claude, Jenny, Chen, Kexin, Cook, Linda S, Cramer, Daniel W, deFazio, Anna, Dennis, Joe, Doherty, Jennifer A, Dörk, Thilo, Eccles, Diana M, Edwards, Digna Velez, Fasching, Peter A, Fortner, Renée T, Gayther, Simon A, Giles, Graham G, Glasspool, Rosalind M, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Harris, Holly R, Heitz, Florian, Hildebrandt, Michelle A, Høgdall, Estrid, Høgdall, Claus K, Huntsman, David G, Kar, Siddhartha P, Karlan, Beth Y, Kelemen, Linda E, Kiemeney, Lambertus A, Kjaer, Susanne K, Koushik, Anita, Lambrechts, Diether, Le, Nhu D, Levine, Douglas A, Massuger, Leon F, Matsuo, Keitaro, May, Taymaa, McNeish, Iain A, Menon, Usha, Modugno, Francesmary, Monteiro, Alvaro N, Moorman, Patricia G, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Olsson, Håkan, Onland-Moret, N Charlotte, Park, Sue K, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Phelan, Catherine M, Pike, Malcolm C, Ramus, Susan J, Riboli, Elio, Rodriguez-Antona, Cristina, Romieu, Isabelle, Sandler, Dale P, Schildkraut, Joellen M, Setiawan, Veronica W, Shan, Kang, Siddiqui, Nadeem, Sieh, Weiva, Stampfer, Meir J, Sutphen, Rebecca, Swerdlow, Anthony J, Szafron, Lukasz M, Teo, Soo Hwang, Tworoger, Shelley S, Tyrer, Jonathan P, Webb, Penelope M, Wentzensen, Nicolas, White, Emily, Willett, Walter C, Wolk, Alicja, Woo, Yin Ling, Wu, Anna H, Yan, Li, Yannoukakos, Drakoulis, Chenevix-Trench, Georgia, Sellers, Thomas A, Pharoah, Paul DP, Zheng, Wei, and Long, Jirong

Subjects
Biological Sciences, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Genetics, Biotechnology, Rare Diseases, Ovarian Cancer, Cancer Genomics, Prevention, Women's Health, Cancer, Clinical Research, Human Genome, 2.1 Biological and endogenous factors, Biomarkers, Tumor, Carcinoma, Ovarian Epithelial, Cohort Studies, DNA Methylation, Female, Genetic Predisposition to Disease, Humans, Models, Genetic, Ovarian Neoplasms, Predictive Value of Tests, Risk, White People, Oncology & Carcinogenesis, Biochemistry and cell biology, Oncology and carcinogenesis
Abstract

DNA methylation is instrumental for gene regulation. Global changes in the epigenetic landscape have been recognized as a hallmark of cancer. However, the role of DNA methylation in epithelial ovarian cancer (EOC) remains unclear. In this study, high-density genetic and DNA methylation data in white blood cells from the Framingham Heart Study (N = 1,595) were used to build genetic models to predict DNA methylation levels. These prediction models were then applied to the summary statistics of a genome-wide association study (GWAS) of ovarian cancer including 22,406 EOC cases and 40,941 controls to investigate genetically predicted DNA methylation levels in association with EOC risk. Among 62,938 CpG sites investigated, genetically predicted methylation levels at 89 CpG were significantly associated with EOC risk at a Bonferroni-corrected threshold of P < 7.94 × 10-7. Of them, 87 were located at GWAS-identified EOC susceptibility regions and two resided in a genomic region not previously reported to be associated with EOC risk. Integrative analyses of genetic, methylation, and gene expression data identified consistent directions of associations across 12 CpG, five genes, and EOC risk, suggesting that methylation at these 12 CpG may influence EOC risk by regulating expression of these five genes, namely MAPT, HOXB3, ABHD8, ARHGAP27, and SKAP1. We identified novel DNA methylation markers associated with EOC risk and propose that methylation at multiple CpG may affect EOC risk via regulation of gene expression. SIGNIFICANCE: Identification of novel DNA methylation markers associated with EOC risk suggests that methylation at multiple CpG may affect EOC risk through regulation of gene expression.

Published
2019

6. Racial/ethnic differences in the epidemiology of ovarian cancer: a pooled analysis of 12 case-control studies.

Author

Peres, Lauren C, Risch, Harvey, Terry, Kathryn L, Webb, Penelope M, Goodman, Marc T, Wu, Anna H, Alberg, Anthony J, Bandera, Elisa V, Barnholtz-Sloan, Jill, Bondy, Melissa L, Cote, Michele L, Funkhouser, Ellen, Moorman, Patricia G, Peters, Edward S, Schwartz, Ann G, Terry, Paul D, Manichaikul, Ani, Abbott, Sarah E, Camacho, Fabian, Jordan, Susan J, Nagle, Christina M, Australian Ovarian Cancer Study Group, Anne Rossing, Mary, Doherty, Jennifer A, Modugno, Francesmary, Moysich, Kirsten, Ness, Roberta, Berchuck, Andrew, Cook, Linda, Le, Nhu, Brooks-Wilson, Angela, Sieh, Weiva, Whittemore, Alice, McGuire, Valerie, Rothstein, Joseph, Anton-Culver, Hoda, Ziogas, Argyrios, Pearce, Celeste L, Tseng, Chiuchen, Pike, Malcom, Schildkraut, Joellen M, and African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium

Subjects
Australian Ovarian Cancer Study Group, African American Cancer Epidemiology Study and the Ovarian Cancer Association Consortium, Statistics, Public Health and Health Services, Epidemiology
Published
2018

8. Common variants at 19p13 are associated with susceptibility to ovarian cancer (vol 42, pg 880, 2010)

Author

Bolton, Kelly L, Tyrer, Jonathan, Song, Honglin, Ramus, Susan J, Notaridou, Maria, Jones, Chris, Sher, Tanya, Gentry-Maharaj, Aleksandra, Wozniak, Eva, Tsai, Ya-Yu, Weidhaas, Joanne, Paik, Daniel, Van den Berg, David J, Stram, Daniel O, Pearce, Celeste Leigh, Wu, Anna H, Brewster, Wendy, Anton-Culver, Hoda, Ziogas, Argyrios, Narod, Steven A, Levine, Douglas A, Kaye, Stanley B, Brown, Robert, Paul, Jim, Flanagan, James, Sieh, Weiva, McGuire, Valerie, Whittemore, Alice S, Campbell, Ian, Gore, Martin E, Lissowska, Jolanta, Yang, Hanna P, Medrek, Krzysztof, Gronwald, Jacek, Lubinski, Jan, Jakubowska, Anna, Le, Nhu D, Cook, Linda S, Kelemen, Linda E, Brooks-Wilson, Angela, Massuger, Leon FAG, Kiemeney, Lambertus A, Aben, Katja KH, van Altena, Anne M, Houlston, Richard, Tomlinson, Ian, Palmieri, Rachel T, Moorman, Patricia G, Schildkraut, Joellen, Iversen, Edwin S, Phelan, Catherine, Vierkant, Robert A, Cunningham, Julie M, Goode, Ellen L, Fridley, Brooke L, Kruger-Kjaer, Susan, Blaeker, Jan, Hogdall, Estrid, Hogdall, Claus, Gross, Jenny, Karlan, Beth Y, Ness, Roberta B, Edwards, Robert P, Odunsi, Kunle, Moyisch, Kirsten B, Baker, Julie A, Modugno, Francesmary, Heikkinenen, Tuomas, Butzow, Ralf, Nevanlinna, Heli, Leminen, Arto, Bogdanova, Natalia, Antonenkova, Natalia, Doerk, Thilo, Hillemanns, Peter, Duerst, Matthias, Runnebaum, Ingo, Thompson, Pamela J, Carney, Michael E, Goodman, Marc T, Lurie, Galina, Wang-Gohrke, Shan, Hein, Rebecca, Chang-Claude, Jenny, Rossing, Mary Anne, Cushing-Haugen, Kara L, Doherty, Jennifer, Chen, Chu, Rafnar, Thorunn, Besenbacher, Soren, Sulem, Patrick, Stefansson, Kari, Birrer, Michael J, Terry, Kathryn L, Hernandez, Dena, Cramer, Daniel W, Vergote, Ignace, Amant, Frederic, Lambrechts, Diether, and Despierre, Evelyn

Subjects
Developmental Biology, Biological Sciences, Medical and Health Sciences
Published
2016

9. Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer.

Author

Bolton, Kelly L, Tyrer, Jonathan, Song, Honglin, Ramus, Susan J, Notaridou, Maria, Jones, Chris, Sher, Tanya, Gentry-Maharaj, Aleksandra, Wozniak, Eva, Tsai, Ya-Yu, Weidhaas, Joanne, Paik, Daniel, Van Den Berg, David J, Stram, Daniel O, Pearce, Celeste Leigh, Wu, Anna H, Brewster, Wendy, Anton-Culver, Hoda, Ziogas, Argyrios, Narod, Steven A, Levine, Douglas A, Kaye, Stanley B, Brown, Robert, Paul, Jim, Flanagan, James, Sieh, Weiva, McGuire, Valerie, Whittemore, Alice S, Campbell, Ian, Gore, Martin E, Lissowska, Jolanta, Yang, Hanna P, Medrek, Krzysztof, Gronwald, Jacek, Lubinski, Jan, Jakubowska, Anna, Le, Nhu D, Cook, Linda S, Kelemen, Linda E, Brooks-Wilson, Angela, Massuger, Leon FAG, Kiemeney, Lambertus A, Aben, Katja KH, van Altena, Anne M, Houlston, Richard, Tomlinson, Ian, Palmieri, Rachel T, Moorman, Patricia G, Schildkraut, Joellen, Iversen, Edwin S, Phelan, Catherine, Vierkant, Robert A, Cunningham, Julie M, Goode, Ellen L, Fridley, Brooke L, Kruger-Kjaer, Susan, Blaeker, Jan, Hogdall, Estrid, Hogdall, Claus, Gross, Jenny, Karlan, Beth Y, Ness, Roberta B, Edwards, Robert P, Odunsi, Kunle, Moyisch, Kirsten B, Baker, Julie A, Modugno, Francesmary, Heikkinenen, Tuomas, Butzow, Ralf, Nevanlinna, Heli, Leminen, Arto, Bogdanova, Natalia, Antonenkova, Natalia, Doerk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Thompson, Pamela J, Carney, Michael E, Goodman, Marc T, Lurie, Galina, Wang-Gohrke, Shan, Hein, Rebecca, Chang-Claude, Jenny, Rossing, Mary Anne, Cushing-Haugen, Kara L, Doherty, Jennifer, Chen, Chu, Rafnar, Thorunn, Besenbacher, Soren, Sulem, Patrick, Stefansson, Kari, Birrer, Michael J, Terry, Kathryn L, Hernandez, Dena, Cramer, Daniel W, Vergote, Ignace, Amant, Frederic, Lambrechts, Diether, and Despierre, Evelyn

Subjects
Australian Ovarian Cancer Study Group, Rare Diseases, Cancer, Ovarian Cancer, Biological Sciences, Medical and Health Sciences, Developmental Biology
Published
2016

10. Ovarian Cancer in Women of African Ancestry (OCWAA) consortium : a resource of harmonized data from eight epidemiologic studies of African American and white women

Author

Schildkraut, Joellen M., Peres, Lauren C., Bethea, Traci N., Camacho, Fabian, Chyn, Deanna, Cloyd, Emily K., Bandera, Elisa V., Beeghly-Fadiel, Alicia, Lipworth, Loren, Joslin, Charlotte E., Davis, Faith G., Moorman, Patricia G., Myers, Evan, Ochs-Balcom, Heather M., Setiawan, Veronica Wendy, Pike, Malcolm C., Wu, Anna H., and Rosenberg, Lynn

Published
2019

11. Long-term risk of medical conditions associated with breast cancer treatment

Author

Hill, Deirdre A, Horick, Nora K, Isaacs, Claudine, Domchek, Susan M, Tomlinson, Gail E, Lowery, Jan T, Kinney, Anita Y, Berg, Jonathan S, Edwards, Karen L, Moorman, Patricia G, Plon, Sharon E, Strong, Louise C, Ziogas, Argyrois, Griffin, Constance A, Kasten, Carol H, and Finkelstein, Dianne M

Subjects
Osteoporosis, Clinical Research, Prevention, Breast Cancer, Aging, Rehabilitation, Cancer, Cardiovascular, Heart Disease, Heart Disease - Coronary Heart Disease, Detection, screening and diagnosis, 4.2 Evaluation of markers and technologies, Adult, Aged, Antineoplastic Agents, Bone Diseases, Metabolic, Breast Neoplasms, Female, Heart Diseases, Humans, Lymph Node Excision, Lymphedema, Middle Aged, Prevalence, Radiotherapy, Risk Factors, Surveys and Questionnaires, Survivors, Breast neoplasms, Heart disease, Chemotherapy, Clinical Sciences, Oncology and Carcinogenesis, Oncology & Carcinogenesis
Abstract

Early and late effects of cancer treatment are of increasing concern with growing survivor populations, but relevant data are sparse. We sought to determine the prevalence and hazard ratio of such effects in breast cancer cases. Women with invasive breast cancer and women with no cancer history recruited for a cancer research cohort completed a mailed questionnaire at a median of 10 years post-diagnosis or matched reference year (for the women without cancer). Reported medical conditions including lymphedema, osteopenia, osteoporosis, and heart disease (congestive heart failure, myocardial infarction, coronary heart disease) were assessed in relation to breast cancer therapy and time since diagnosis using Cox regression. The proportion of women currently receiving treatment for these conditions was calculated. Study participants included 2,535 women with breast cancer and 2,428 women without cancer (response rates 66.0 % and 50.4 %, respectively) Women with breast cancer had an increased risk of lymphedema (Hazard ratio (HR) 8.6; 95 % confidence interval (CI) 6.3-11.6), osteopenia (HR 2.1; 95 % CI 1.8-2.4), and osteoporosis (HR 1.5; 95 % CI 1.2-1.9) but not heart disease, compared to women without cancer Hazard ratios varied by treatment and time since diagnosis. Overall, 49.3 % of breast cancer cases reported at least one medical condition, and at 10 or more years post-diagnosis, 37.7 % were currently receiving condition-related treatment. Responses from survivors a decade following cancer diagnosis demonstrate substantial treatment-related morbidity, and emphasize the need for continued medical surveillance and follow-up care into the second decade post-diagnosis.

Published
2014

14. Common variants at 19p13 are associated with susceptibility to ovarian cancer.

Author

Bolton, Kelly L, Tyrer, Jonathan, Song, Honglin, Ramus, Susan J, Notaridou, Maria, Jones, Chris, Sher, Tanya, Gentry-Maharaj, Aleksandra, Wozniak, Eva, Tsai, Ya-Yu, Weidhaas, Joanne, Paik, Daniel, Van Den Berg, David J, Stram, Daniel O, Pearce, Celeste Leigh, Wu, Anna H, Brewster, Wendy, Anton-Culver, Hoda, Ziogas, Argyrios, Narod, Steven A, Levine, Douglas A, Kaye, Stanley B, Brown, Robert, Paul, Jim, Flanagan, James, Sieh, Weiva, McGuire, Valerie, Whittemore, Alice S, Campbell, Ian, Gore, Martin E, Lissowska, Jolanta, Yang, Hanna P, Medrek, Krzysztof, Gronwald, Jacek, Lubinski, Jan, Jakubowska, Anna, Le, Nhu D, Cook, Linda S, Kelemen, Linda E, Brooks-Wilson, Angela, Massuger, Leon FAG, Kiemeney, Lambertus A, Aben, Katja KH, van Altena, Anne M, Houlston, Richard, Tomlinson, Ian, Palmieri, Rachel T, Moorman, Patricia G, Schildkraut, Joellen, Iversen, Edwin S, Phelan, Catherine, Vierkant, Robert A, Cunningham, Julie M, Goode, Ellen L, Fridley, Brooke L, Kruger-Kjaer, Susan, Blaeker, Jan, Hogdall, Estrid, Hogdall, Claus, Gross, Jenny, Karlan, Beth Y, Ness, Roberta B, Edwards, Robert P, Odunsi, Kunle, Moyisch, Kirsten B, Baker, Julie A, Modugno, Francesmary, Heikkinenen, Tuomas, Butzow, Ralf, Nevanlinna, Heli, Leminen, Arto, Bogdanova, Natalia, Antonenkova, Natalia, Doerk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Thompson, Pamela J, Carney, Michael E, Goodman, Marc T, Lurie, Galina, Wang-Gohrke, Shan, Hein, Rebecca, Chang-Claude, Jenny, Rossing, Mary Anne, Cushing-Haugen, Kara L, Doherty, Jennifer, Chen, Chu, Rafnar, Thorunn, Besenbacher, Soren, Sulem, Patrick, Stefansson, Kari, Birrer, Michael J, Terry, Kathryn L, Hernandez, Dena, Cramer, Daniel W, Vergote, Ignace, Amant, Frederic, Lambrechts, Diether, and Despierre, Evelyn

Subjects
Australian Ovarian Cancer Study Group, Australian Cancer Study, Ovarian Cancer Association Consortium, Ovary, Tumor Cells, Cultured, Chromosomes, Human, Pair 19, Humans, Adenocarcinoma, Clear Cell, Adenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Ovarian Neoplasms, Endometrial Neoplasms, Genetic Predisposition to Disease, Adaptor Proteins, Signal Transducing, Oligonucleotide Array Sequence Analysis, Case-Control Studies, Gene Expression Profiling, Genotype, Polymorphism, Single Nucleotide, Genome, Human, Middle Aged, Female, Genome-Wide Association Study, Biomarkers, Tumor, Tumor Cells, Cultured, Chromosomes, Human, Pair 19, Adenocarcinoma, Clear Cell, Mucinous, Cystadenocarcinoma, Serous, Adaptor Proteins, Signal Transducing, Polymorphism, Single Nucleotide, Genome, Biomarkers, Tumor, Cancer, Human Genome, Genetics, Ovarian Cancer, Orphan Drug, Rare Diseases, 2.1 Biological and endogenous factors, Developmental Biology, Medical and Health Sciences, Biological Sciences
Abstract

Epithelial ovarian cancer (EOC) is the leading cause of death from gynecological malignancy in the developed world, accounting for 4% of the deaths from cancer in women. We performed a three-phase genome-wide association study of EOC survival in 8,951 individuals with EOC (cases) with available survival time data and a parallel association analysis of EOC susceptibility. Two SNPs at 19p13.11, rs8170 and rs2363956, showed evidence of association with survival (overall P = 5 × 10⁻⁴ and P = 6 × 10⁻⁴, respectively), but they did not replicate in phase 3. However, the same two SNPs demonstrated genome-wide significance for risk of serous EOC (P = 3 × 10⁻⁹ and P = 4 × 10⁻¹¹, respectively). Expression analysis of candidate genes at this locus in ovarian tumors supported a role for the BRCA1-interacting gene C19orf62, also known as MERIT40, which contains rs8170, in EOC development.

Published
2010

15. Evaluation of Candidate Stromal Epithelial Cross-Talk Genes Identifies Association between Risk of Serous Ovarian Cancer and TERT, a Cancer Susceptibility �Hot-Spot�

Author

Johnatty, Sharon E, Beesley, Jonathan, Chen, Xiaoqing, Macgregor, Stuart, Duffy, David L, Spurdle, Amanda B, deFazio, Anna, Gava, Natalie, Webb, Penelope M, Rossing, Mary Anne, Doherty, Jennifer Anne, Goodman, Marc T, Lurie, Galina, Thompson, Pamela J, Wilkens, Lynne R, Ness, Roberta B, Moysich, Kirsten B, Chang-Claude, Jenny, Wang-Gohrke, Shan, Cramer, Daniel W, Terry, Kathryn L, Hankinson, Susan E, Tworoger, Shelley S, Garcia-Closas, Montserrat, Yang, Hannah, Lissowska, Jolanta, Chanock, Stephen J, Pharoah, Paul D, Song, Honglin, Whitemore, Alice S, Pearce, Celeste L, Stram, Daniel O, Wu, Anna H, Pike, Malcolm C, Gayther, Simon A, Ramus, Susan J, Menon, Usha, Gentry-Maharaj, Aleksandra, Anton-Culver, Hoda, Ziogas, Argyrios, Hogdall, Estrid, Kjaer, Susanne K, Hogdall, Claus, Berchuck, Andrew, Schildkraut, Joellen M, Iversen, Edwin S, Moorman, Patricia G, Phelan, Catherine M, Sellers, Thomas A, Cunningham, Julie M, Vierkant, Robert A, Rider, David N, Goode, Ellen L, Haviv, Izhak, Chenevix-Trench, Georgia, Dermitzakis, Emmanouil T, and Ovarian Cancer Association Consortium", .

Subjects
genome-wide association, single-nucleotide polymorphisms, incessant ovulation, colorectal-cancer, expression, consortium, variants, prostate, locus, myc
Abstract

We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility. We therefore used a two-stage approach to evaluate common single nucleotide polymorphisms (SNPs) in 173 genes involved in stromal epithelial interactions in the Ovarian Cancer Association Consortium (OCAC). In the discovery stage, cases with epithelial ovarian cancer (n = 675) and controls (n = 1,162) were genotyped at 1,536 SNPs using an Illumina GoldenGate assay. Based on Positive Predictive Value estimates, three SNPs-PODXL rs1013368, ITGA6 rs13027811, and MMP3 rs522616-were selected for replication using TaqMan genotyping in up to 3,059 serous invasive cases and 8,905 controls from 16 OCAC case-control studies. An additional 18 SNPs with P(per-allele)= 0.5). However genotypes at TERT rs7726159 were associated with ovarian cancer risk in the smaller, five-study replication study (P(per-allele)=0.03). Combined analysis of the discovery and replication sets for this TERT SNP showed an increased risk of serous ovarian cancer among non-Hispanic whites [adj. OR(per-allele) 1.14 (1.04-1.24) p = 0.003]. Our study adds to the growing evidence that, like the 8q24 locus, the telomerase reverse transcriptase locus at 5p15.33, is a general cancer susceptibility locus.

Published
2010

16. Tubal ligation and ovarian cancer risk in African American women

Author

McNamara, Chrissy, Abbott, Sarah E., Bandera, Elisa V., Qin, Bo, Peres, Lauren C., Camacho, Fabian, Moorman, Patricia G., Alberg, Anthony J., Barnholtz-Sloan, Jill S., Bondy, Melissa, Cote, Michele L., Funkhouser, Ellen, Peters, Edward S., Schwartz, Ann G., Schildkraut, Joellen M., and Terry, Paul

Published
2017

18. Cigarette smoking and the association with serous ovarian cancer in African American women : African American Cancer Epidemiology Study (AACES)

Author

Kelemen, Linda E., Abbott, Sarah, Qin, Bo, Peres, Lauren Cole, Moorman, Patricia G., Wallace, Kristin, Bandera, Elisa V., Barnholtz-Sloan, Jill S., Bondy, Melissa, Cartmell, Kathleen, Cote, Michele L., Funkhouser, Ellen, Paddock, Lisa E., Peters, Edward S., Schwartz, Ann G., Terry, Paul, Alberg, Anthony J., and Schildkraut, Joellen M.

Published
2017

20. Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study

Author

Song, Honglin, Ramus, Susan J, Kjaer, Susanne Krüger, DiCioccio, Richard A, Chenevix-Trench, Georgia, Pearce, Celeste Leigh, Hogdall, Estrid, Whittemore, Alice S, McGuire, Valerie, Hogdall, Claus, Blaakaer, Jan, Wu, Anna H, Van Den Berg, David J, Stram, Daniel O, Menon, Usha, Gentry-Maharaj, Aleksandra, Jacobs, Ian J, Webb, Penny M, Beesley, Jonathan, Chen, Xiaoqing, Rossing, Mary Anne, Doherty, Jennifer A, Chang-Claude, Jenny, Wang-Gohrke, Shan, Goodman, Marc T, Lurie, Galina, Thompson, Pamela J, Carney, Michael E, Ness, Roberta B, Moysich, Kirsten, Goode, Ellen L, Vierkant, Robert A, Cunningham, Julie M, Anderson, Stephanie, Schildkraut, Joellen M, Berchuck, Andrew, Iversen, Edwin S, Moorman, Patricia G, Garcia-Closas, Montserrat, Chanock, Stephen, Lissowska, Jolanta, Brinton, Louise, Anton-Culver, Hoda, Ziogas, Argyrios, Brewster, Wendy R, Ponder, Bruce AJ, Easton, Douglas F, Gayther, Simon A, and Pharoah, Paul DP

Subjects
Biological Sciences, Genetics, Prevention, Human Genome, Ovarian Cancer, Clinical Research, Cancer, Breast Cancer, Aging, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Breast Neoplasms, Case-Control Studies, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Glycoproteins, Humans, Neuropeptides, Ovarian Neoplasms, Polymorphism, Single Nucleotide, Risk Factors, White People, Australian Cancer (Ovarian) Study, Australian Ovarian Cancer Study Group, Ovarian Cancer Association Consortium, Medical and Health Sciences, Genetics & Heredity
Abstract

Because both ovarian and breast cancer are hormone-related and are known to have some predisposition genes in common, we evaluated 11 of the most significant hits (six with confirmed associations with breast cancer) from the breast cancer genome-wide association study for association with invasive ovarian cancer. Eleven SNPs were initially genotyped in 2927 invasive ovarian cancer cases and 4143 controls from six ovarian cancer case-control studies. Genotype frequencies in cases and controls were compared using a likelihood ratio test in a logistic regression model stratified by study. Initially, three SNPs (rs2107425 in MRPL23, rs7313833 in PTHLH, rs3803662 in TNRC9) were weakly associated with ovarian cancer risk and one SNP (rs4954956 in NXPH2) was associated with serous ovarian cancer in non-Hispanic white subjects (P-trend < 0.1). These four SNPs were then genotyped in an additional 4060 cases and 6308 controls from eight independent studies. Only rs4954956 was significantly associated with ovarian cancer risk both in the replication study and in combined analyses. This association was stronger for the serous histological subtype [per minor allele odds ratio (OR) 1.07 95% CI 1.01-1.13, P-trend = 0.02 for all types of ovarian cancer and OR 1.14 95% CI 1.07-1.22, P-trend = 0.00017 for serous ovarian cancer]. In conclusion, we found that rs4954956 was associated with increased ovarian cancer risk, particularly for serous ovarian cancer. However, none of the six confirmed breast cancer susceptibility variants we tested was associated with ovarian cancer risk. Further work will be needed to identify the causal variant associated with rs4954956 or elucidate its function.

Published
2009

29. Racial Differences in the Association of Endometriosis and Uterine Leiomyomas With the Risk of Ovarian Cancer

Author

Harris, Holly R., primary, Peres, Lauren C., additional, Johnson, Courtney E., additional, Guertin, Kristin A., additional, Beeghly, Alicia, additional, Bandera, Elisa V., additional, Bethea, Traci N., additional, Joslin, Charlotte E., additional, Wu, Anna H., additional, Moorman, Patricia G., additional, Ochs-Balcom, Heather M., additional, Petrick, Jessica L., additional, Setiawan, Veronica W., additional, Rosenberg, Lynn, additional, Schildkraut, Joellen M., additional, and Myers, Evan, additional

Published
2023
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30. Supplementary Table 3 from Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review

Author

Gierisch, Jennifer M., primary, Coeytaux, Remy R., primary, Urrutia, Rachel Peragallo, primary, Havrilesky, Laura J., primary, Moorman, Patricia G., primary, Lowery, William J., primary, Dinan, Michaela, primary, McBroom, Amanda J., primary, Hasselblad, Vic, primary, Sanders, Gillian D., primary, and Myers, Evan R., primary

Published
2023
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31. Supplementary Tables 1-2 from Genetic Variation in TYMS in the One-Carbon Transfer Pathway Is Associated with Ovarian Carcinoma Types in the Ovarian Cancer Association Consortium

Author

Kelemen, Linda E., primary, Goodman, Marc T., primary, McGuire, Valerie, primary, Rossing, Mary Anne, primary, Webb, Penelope M., primary, Köbel, Martin, primary, Anton-Culver, Hoda, primary, Beesley, Jonathan, primary, Berchuck, Andrew, primary, Brar, Sony, primary, Carney, Michael E., primary, Chang-Claude, Jenny, primary, Chenevix-Trench, Georgia, primary, Cramer, Daniel W., primary, Cunningham, Julie M., primary, DiCioccio, Richard A., primary, Doherty, Jennifer A., primary, Easton, Douglas F., primary, Fredericksen, Zachary S., primary, Fridley, Brooke L., primary, Gates, Margaret A., primary, Gayther, Simon A., primary, Gentry-Maharaj, Aleksandra, primary, Høgdall, Estrid, primary, Kjær, Susanne Krüger, primary, Lurie, Galina, primary, Menon, Usha, primary, Moorman, Patricia G., primary, Moysich, Kirsten, primary, Ness, Roberta B., primary, Palmieri, Rachel T., primary, Pearce, Celeste L., primary, Pharoah, Paul D.P., primary, Ramus, Susan J., primary, Song, Honglin, primary, Stram, Daniel O., primary, Tworoger, Shelley S., primary, Van Den Berg, David, primary, Vierkant, Robert A., primary, Wang-Gohrke, Shan, primary, Whittemore, Alice S., primary, Wilkens, Lynne R., primary, Wu, Anna H., primary, Schildkraut, Joellen M., primary, Sellers, Thomas A., primary, and Goode, Ellen L., primary

Published
2023
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32. Supplementary Table 2 from Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review

Author

Gierisch, Jennifer M., primary, Coeytaux, Remy R., primary, Urrutia, Rachel Peragallo, primary, Havrilesky, Laura J., primary, Moorman, Patricia G., primary, Lowery, William J., primary, Dinan, Michaela, primary, McBroom, Amanda J., primary, Hasselblad, Vic, primary, Sanders, Gillian D., primary, and Myers, Evan R., primary

Published
2023
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33. Supplementary Table 4 from Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review

Author

Gierisch, Jennifer M., primary, Coeytaux, Remy R., primary, Urrutia, Rachel Peragallo, primary, Havrilesky, Laura J., primary, Moorman, Patricia G., primary, Lowery, William J., primary, Dinan, Michaela, primary, McBroom, Amanda J., primary, Hasselblad, Vic, primary, Sanders, Gillian D., primary, and Myers, Evan R., primary

Published
2023
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34. Supplementary Table 1 from Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review

Author

Gierisch, Jennifer M., primary, Coeytaux, Remy R., primary, Urrutia, Rachel Peragallo, primary, Havrilesky, Laura J., primary, Moorman, Patricia G., primary, Lowery, William J., primary, Dinan, Michaela, primary, McBroom, Amanda J., primary, Hasselblad, Vic, primary, Sanders, Gillian D., primary, and Myers, Evan R., primary

Published
2023
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35. Data from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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36. Supplementary Table 3 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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37. Supplementary Figure 2 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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38. Supplementary Figure 1 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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39. Supplementary Table 1 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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40. Supplementary Table 2 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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41. Supplementary Table 4 from Single Nucleotide Polymorphisms in the TP53 Region and Susceptibility to Invasive Epithelial Ovarian Cancer

Author

Schildkraut, Joellen M., primary, Goode, Ellen L., primary, Clyde, Merlise A., primary, Iversen, Edwin S., primary, Moorman, Patricia G., primary, Berchuck, Andrew, primary, Marks, Jeffrey R., primary, Lissowska, Jolanta, primary, Brinton, Louise, primary, Peplonska, Beata, primary, Cunningham, Julie M., primary, Vierkant, Robert A., primary, Rider, David N., primary, Chenevix-Trench, Georgia, primary, Webb, Penelope M., primary, Beesley, Jonathan, primary, Chen, Xiaoqing, primary, Phelan, Catherine, primary, Sutphen, Rebecca, primary, Sellers, Thomas A., primary, Pearce, Leigh, primary, Wu, Anna H., primary, Van Den Berg, David, primary, Conti, David, primary, Elund, Christopher K., primary, Anderson, Rebecca, primary, Goodman, Marc T., primary, Lurie, Galina, primary, Carney, Michael E., primary, Thompson, Pamela J., primary, Gayther, Simon A., primary, Ramus, Susan J., primary, Jacobs, Ian, primary, Krüger Kjaer, Susanne, primary, Hogdall, Estrid, primary, Blaakaer, Jan, primary, Hogdall, Claus, primary, Easton, Douglas F., primary, Song, Honglin, primary, Pharoah, Paul D.P., primary, Whittemore, Alice S., primary, McGuire, Valerie, primary, Quaye, Lydia, primary, Anton-Culver, Hoda, primary, Ziogas, Argyrios, primary, Terry, Kathryn L., primary, Cramer, Daniel W., primary, Hankinson, Susan E., primary, Tworoger, Shelley S., primary, Calingaert, Brian, primary, Chanock, Stephen, primary, Sherman, Mark, primary, and Garcia-Closas, Montserrat, primary

Published
2023
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43. Labor Dystocia

Author

Myers, Evan R., primary, Sanders, Gillian D., additional, Coeytaux, Remy R., additional, McElligott, Kara A., additional, Moorman, Patricia G., additional, Hicklin, Karen, additional, Grotegut, Chad, additional, Villers, Margaret, additional, Goode, Adam, additional, Campbell, Hilary, additional, Befus, Deanna, additional, McBroom, Amanda J., additional, Davis, J. Kelly, additional, Lallinger, Kathryn, additional, Fortman, Robyn, additional, and Kosinski, Andrzej, additional

Published
2020
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44. Targetable Immune Regulatory Molecule Expression in High-Grade Serous Ovarian Carcinomas in African American Women: A Study of PD-L1 and IDO in 112 Cases From the African American Cancer Epidemiology Study (AACES)

Author

Mills, Anne M., Peres, Lauren C., Meiss, Alice, Ring, Kari L., Modesitt, Susan C., Abbott, Sarah E., Alberg, Anthony J., Bandera, Elisa V., Barnholtz-Sloan, Jill, Bondy, Melissa L., Cote, Michele L., Funkhouser, Ellen, Moorman, Patricia G., Peters, Edward S., Schwartz, Ann G., Terry, Paul D., Wallace, Kristin, and Schildkraut, Joellen M.

Published
2019
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47. Factors Associated with Adherence to Follow-up Colposcopy

Author

Fish, Laura J., Moorman, Patricia G., Wordlaw-Stintson, Lashawn, Vidal, Adriana, Smith, Jennifer S., and Hoyo, Cathrine

Abstract

Background: Understanding the gaps in knowledge about human papilloma virus (HPV) infection, transmission, and health consequences and factors associated with the knowledge gap is an essential first step for the development of interventions to improve adherence to follow-up among women with abnormal Pap smears. Purpose: To examine the relationship between knowledge about HPV and adherence to scheduled colposcopic evaluation and variables related to lack of knowledge among women with abnormal Pap tests. Methods: Telephone surveys were conducted with women who attended their scheduled appointments (adherers) and women who did not attend their appointments (nonadherers). Results: The multivariable analyses indicate that lower HPV knowledge was independently associated with nonadherence to follow-up, controlling for race and education level. Factors related to lower knowledge scores included non-white race, lower education, and lack of health insurance at the time of the scheduled appointment. Conclusion: Lack of knowledge of HPV was related to nonadherence among women scheduled for colposcopic evaluation. Translation to Health Education Practice: Health education interventions that deliver complex information about HPV and cervical cancer should be in a format that is accessible and understandable to the women who are most at risk of being nonadherent.

Published
2013
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48. Management of Infertility

Author

Myers, Evan R., primary, Eaton, Jennifer L., additional, McElligott, Kara A., additional, Moorman, Patricia G., additional, Chatterjee, Ranee, additional, Zakama, Arthurine K., additional, Goldstein, Karen, additional, Strauss, Jennifer, additional, Coeytaux, Remy R., additional, Goode, Adam, additional, Borre, Ethan, additional, Swamy, Geeta K., additional, McBroom, Amanda J., additional, Lallinger, Kathryn, additional, Schmidt, Robyn, additional, Davis, J. Kelly, additional, Hasselblad, Victor, additional, and Sanders, Gillian D., additional

Published
2019
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49. Racial disparities in epithelial ovarian cancer survival: An examination of contributing factors in the Ovarian Cancer in Women of African Ancestry consortium

Author

Harris, Holly R., primary, Guertin, Kristin A., additional, Camacho, Tareq F., additional, Johnson, Courtney E., additional, Wu, Anna H., additional, Moorman, Patricia G., additional, Myers, Evan, additional, Bethea, Traci N., additional, Bandera, Elisa V., additional, Joslin, Charlotte E., additional, Ochs‐Balcom, Heather M., additional, Peres, Lauren C., additional, Rosenow, Will T., additional, Setiawan, Veronica W., additional, Beeghly‐Fadiel, Alicia, additional, Dempsey, Lauren F., additional, Rosenberg, Lynn, additional, and Schildkraut, Joellen M., additional

Published
2022
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50. Race Differences in the Associations between Menstrual Cycle Characteristics and Epithelial Ovarian Cancer

Author

Nash, Rebecca, primary, Johnson, Courtney E., additional, Harris, Holly R., additional, Peres, Lauren C., additional, Joslin, Charlotte E., additional, Bethea, Traci N., additional, Bandera, Elisa V., additional, Ochs-Balcom, Heather M., additional, Myers, Evan R., additional, Guertin, Kristin A., additional, Camacho, Fabian, additional, Beeghly-Fadiel, Alicia, additional, Moorman, Patricia G., additional, Setiawan, V. Wendy, additional, Rosenberg, Lynn, additional, Schildkraut, Joellen M., additional, and Wu, Anna H., additional

Published
2022
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