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IntroductionSinus histiocytosis with massive lymphadenopathy, also known as Rosai-Dorfman Disease, is a rare and benign source of lymphadenopathy first described in 1969, which mimics neoplastic processes. This disease commonly presents in children and young adults with supra-diaphragmatic lymphadenopathy or extranodal lesions consisting of tissue infiltrates composed of a polyclonal population of histiocytes. Since its description greater than 400 cases have been described, sometimes in patients with a variety of treated and untreated neoplastic diseases. However, the literature contains reports of only 19 cases of Rosai-Dorfman Disease in association with lymphomas, Hodgkin's or non-Hodgkin's. The majority of these cases have the two diagnoses, malignant lymphoma and Rosai-Dorfman Disease, separated in time. Interestingly, infradiaphragmatic lymphadenopathy was a feature in the majority of previously reported cases of Rosai-Dorfman Disease and non-Hodgkin's lymphoma.Case presentationThis report provides details of a case with co-existing sinus histiocytosis with massive lymphadenopathy and diffuse large B cell non-Hodgkin's lymphoma. This case is the fifth described case of simultaneous Rosai-Dorfman Disease and concurrent non-Hodgkin's lymphoma. Unfortunately, the diagnosis of a clinically aggressive diffuse large B cell lymphoma was made at autopsy. The aggressive biological behavior of the diffuse large B cell lymphoma in this patient may have been related to the underlying immune dysregulation believed to be part of the pathophysiology of Rosai-Dorfman Disease.ConclusionTaken together this report and the preceding reports of Rosai-Dorfman Disease and non-Hodgkin's lymphoma suggests that in cases with a diagnosis of Rosai-Dorfman Disease in the setting of prominent infradiaphragmatic lymphadenopathy, clinicians should maintain a high index of suspicion for the presence of occult non-Hodgkin's lymphoma especially if the clinical course is atypical for classic Rosai-Dorfman Disease.

Past studies have documented the home advantage in sports. However, possible explanations for the home advantage have yet to be validated. Post facto causal research opportunities may provide an answer to the phenomenon. One such opportunity arose during the 1992-1993 basketball season when the Western Michigan University men's and women's basketball teams played their home games in five different locations while a new facility was being constructed. Results indicate that the home advantage held for both teams despite their nonfamiliarity with the facilities where they played their games., The home advantage in sports has been widely documented; see Edwards and Archambault, 1989; Courneya and Carron, 1992; for comprehensive reviews of the literature. Plausible explanations of the home advantage [...]

This paper explores a multi-agent resource allocation problem in an environment of incomplete information. The paper posits the existence of a central policy maker who integrates information acquisition with decision making, in order to optimally allocate resources among multiple agents. The study focuses on three salient aspects: First, the policy maker uses a nonparametric revealed preference approach for the elicitation of each agent's preference profiles. This allows the policy maker to avoid distorting the allocation decision and emerging with suboptimal allocations. Second, the process of information gathering and decision making is a challenging task in view of the extremely large numbers of possible profiles for each agent, even for problems of modest size. To find an optimal allocation, the policy maker can use schemes that utilize partial preference information to handle the complexity of the problem. Third, the incorporation of costs into the information process and the minimal assumptions made about the problem environment allow the policy maker to realistically analyze the resource allocation problem.