197 results on '"Montroni, M."'
Search Results
2. Early increase of CD4+ CD45RA+ and CD4+ CD95- cells with conserved repertoire induced by anti-retroviral therapy in HIV-infected patients
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SILVESTRI, G., MUNOZ-CALLEJA, C., BAGNARELLI, P., PIEDIMONTE, G., CLEMENTI, M., and MONTRONI, M.
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- 1998
3. p24 antigenaemia and clinical response to zidovudine therapy
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Montroni, M., Silvestri, G., Butini, L., Regnery, C., Bartocci, C., Buffarini, F., and Danieli, G.
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- 1993
4. Incidence of Malignancies in HIV‐Infected Patients and Prognostic Role of Current CD4 Cell Count: Evidence from a Large Italian Cohort Study
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Prosperi M.C., Cozzi Lepri A., Castagna A., Mussini C., Murri R., Giacometti A., Torti C., Costantini A., Narciso P., Ghinelli F., Antinori A., d'Arminio Monforte A., Moroni M, Carosi G, Galli M, Iardino R, Ippolito G, Lazzarin A, Panebianco R, Pastore G, Perno CF, Ammassari A, Arici C, Balotta C, Bonfanti P, Capobianchi MR, Ceccherini Silberstein F, De Luca A, Gervasoni C, Girardi E, Lo Caputo S, Puoti M, Fanti I, Formenti T, Montroni M, Riva A, Tirelli U, Martellotta F, Ladisa N, Pierri A, Suter F, Maggiolo F, Cristini G, Minardi C, Bertelli D, Quirino D, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Pagano G, Cassola G, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Soscia F, Tacconi L, Orani A, Rossotti R, Tommasi D, Congedo P, Chiodera A, Castelli P, Rizzardini G, Schlacht I, Ridolfo AL, Foschi A, Salpietro S, Merli S, Melzi S, Moioli MC, Cicconi P, Esposito R, Gori A, Fiorino M, Abrescia N, Chirianni A, Izzo CM, De Marco M, Viglietti R, Manzillo E, Ferrari C, Pizzaferri P, Baldelli F, Belfiori B, Magnani G, Ursitti MA, Arlotti M, Ortolani P, Cauda R, Andreoni M, Antonucci G, Tozzi V, Vullo V, Zaccarelli M, Acinapura R, De Longis P, Trotta MP, Calbi M, Gallo L, Miccoli A, Carletti F, Mura MS, Madeddu G, Caramello P, Di Perri G, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D., BORDERI, MARCO, VERUCCHI, GABRIELLA, PIERGENTILI, BENEDETTA, Prosperi MC., Cozzi-Lepri A., Castagna A., Mussini C., Murri R., Giacometti A., Torti C., Costantini A., Narciso P., Ghinelli F., Antinori A., d'Arminio Monforte A., Moroni M, Carosi G, Galli M, Iardino R, Ippolito G, Lazzarin A, Panebianco R, Pastore G, Perno CF, Ammassari A, Arici C, Balotta C, Bonfanti P, Capobianchi MR, Ceccherini-Silberstein F, De Luca A, Gervasoni C, Girardi E, Lo Caputo S, Puoti M, Fanti I, Formenti T, Montroni M, Riva A, Tirelli U, Martellotta F, Ladisa N, Pierri A, Suter F, Maggiolo F, Borderi M, Verucchi G, Piergentili B, Cristini G, Minardi C, Bertelli D, Quirino D, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Pagano G, Cassola G, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Soscia F, Tacconi L, Orani A, Rossotti R, Tommasi D, Congedo P, Chiodera A, Castelli P, Rizzardini G, Schlacht I, Ridolfo AL, Foschi A, Salpietro S, Merli S, Melzi S, Moioli MC, Cicconi P, Esposito R, Gori A, Fiorino M, Abrescia N, Chirianni A, Izzo CM, De Marco M, Viglietti R, Manzillo E, Ferrari C, Pizzaferri P, Baldelli F, Belfiori B, Magnani G, Ursitti MA, Arlotti M, Ortolani P, Cauda R, Andreoni M, Antonucci G, Tozzi V, Vullo V, Zaccarelli M, Acinapura R, De Longis P, Trotta MP, Calbi M, Gallo L, Miccoli A, Carletti F, Mura MS, Madeddu G, Caramello P, Di Perri G, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D., Prosperi, M. C. F., Cozzi lepri, A., Castagna, Antonella, Mussini, C., Murri, R., Giacometti, A., Torti, C., Costantini, A., Narciso, P., Ghinelli, F., Antinori, A., and D'arminio Monforte, A.
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Adult ,Male ,Microbiology (medical) ,tumor ,medicine.medical_specialty ,Prognosi ,Prognosis ,male ,cohort studies ,CD4 lymphocyte count ,HIV infections ,female ,neoplasms ,Italy ,incidence ,adult ,humans ,HIV Infections ,Cohort Studies ,MALIGNANCIES ,HIV ,AIDS ,CD4 ,Neoplasms ,Immunopathology ,Internal medicine ,Epidemiology ,medicine ,Humans ,HIV Infection ,Sida ,biology ,business.industry ,Incidence ,Incidence (epidemiology) ,Settore MED/07 - Microbiologia e Microbiologia Clinica ,biology.organism_classification ,Confidence interval ,CD4 Lymphocyte Count ,Surgery ,Infectious Diseases ,Cohort ,Neoplasm ,Female ,Viral disease ,Cohort Studie ,business ,Human ,Cohort study - Abstract
The incidence of and predictors of acquired immunodeficiency syndrome-defining malignancies (ADMs) and nonADM (NADMs) were evaluated in a large Italian cohort. The incidence of ADM and NADM was 5.0 cases per 1000 personyears of follow-up (95% confidence interval, 4.3-5.8 cases per 1000 person-years of follow-up) and 2.4 cases per 1000 person-years of follow-up (95% confidence interval, 1.9-3.1 cases per 1000 person-years of follow-up), respectively. Lower current CD4 cell count was an independent predictor of developing malignancies, with the association being stronger for ADM than for NADM. © 2010 by the Infectious Diseases Society of America. All rights reserved.
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- 2010
5. HIV-related risk behaviour in UK holiday-makers
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Montroni, M., Silvestri, C., Butini, L., Bartocc, C., Regnery, C., and Danieli, G.
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- 1992
6. Immunological Assessment in Sporadic Amyotrophic Lateral Sclerosis (ALS)
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Provinciali, L., Giovagnoli, A. R., Battucci, S., Bartocci, C., Montroni, M., Cosi, V., editor, Kato, Ann C., editor, Parlette, W., editor, Pinelli, P., editor, and Poloni, M., editor
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- 1987
- Full Text
- View/download PDF
7. Clinical and Immunological Findings After Treatment with Thymostimulin in Multiple Sclerosis
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Giovagnoli, A. R., Provinciali, L., Bartocci, C., Montroni, M., Cazzullo, Carlo L., editor, Caputo, Domenico, editor, Ghezzi, Angelo, editor, and Zaffaroni, Mauro, editor
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- 1988
- Full Text
- View/download PDF
8. Immune activation and microbial translocation in liver disease progression in HIV/hepatitis co-infected patients: results from the Icona Foundation study
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Marchetti, Giulia, Cozzi Lepri, Alessandro, Tincati, Camilla, Calcagno, Andrea, Ceccherini Silberstein, Francesca, De Luca, Andrea, Antinori, Andrea, Castagna, Antonella, Puoti, Massimo, Monforte, Antonella d'Arminio, for the Icona Foundation Study Group […, Moroni M, Angarano G, Antinori A, Carosi G, Cauda R, Monforte A, Di Perri G, Galli M, Iardino R, Ippolito G, Lazzarin A, Perno CF, Viale PL, Von Schlosser F, Monforte Ad, Ammassari A, Andreoni M, Balotta C, Bonfanti P, Bonora S, Borderi M, Capobianchi MR, Castagna A, Ceccherini Silberstein F, Cozzi Lepri A, De Luca A, Gargiulo M, Gervasoni C, Girardi E, Lichtner M, Lo Caputo S, Madeddu G, Maggiolo F, Marcotullio S, Monno L, Murri R, Mussini C, Puoti M, Torti C, Fanti I, Formenti T, Montroni M, Giacometti A, Costantini A, Riva A, Tirelli U, Martellotta F, Ladisa N, Suter F, Piergentili B, Cristini G, Minardi C, Bertelli D, Quirino T, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Cassola G, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Mastroianni C, Belvisi V, Molteni C, Chiodera A, Castelli P, Rizzardini G, Ridolfo AL, Foschi A, Salpietro S, Merli S, Carenzi L, Moioli MC, Cicconi P, Esposito R, Gori A, Pastore V, Abrescia N, Chirianni A, De Marco M, Ferrari C, Borghi R, Baldelli F, Belfiori B, Parruti G, Sozio F, Magnani G, Ursitti MA, Arlotti M, Ortolani P, Antonucci G, Narciso P, Tozzi V, Vullo V, Zaccarelli M, Gallo L, Acinapura R, De Longis P, Ceccarelli L, Libertone R, Trotta MP, Miccoli A, Cattelan AM, Mura MS, Caramello P, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D, VERUCCHI, GABRIELLA, Marchetti, G, Cozzi Lepri, A, Tincati, C, Calcagno, A, Ceccherini Silberstein, F, DE LUCA, A, Antinori, A, Castagna, A, Puoti, M, Monforte, A, Marchetti, Giulia, Cozzi Lepri, Alessandro, Tincati, Camilla, Calcagno, Andrea, Ceccherini Silberstein, Francesca, De Luca, Andrea, Antinori, Andrea, Castagna, Antonella, Puoti, Massimo, Monforte Antonella, D'Arminio, Cozzi-Lepri, Alessandro, Ceccherini-Silberstein, Francesca, Monforte, Antonella d'Arminio, and for the Icona Foundation Study Group […, Moroni M, Angarano G, Antinori A, Carosi G, Cauda R, Monforte A, Di Perri G, Galli M, Iardino R, Ippolito G, Lazzarin A, Perno CF, Viale PL, Von Schlosser F, Monforte Ad, Ammassari A, Andreoni M, Balotta C, Bonfanti P, Bonora S, Borderi M, Capobianchi MR, Castagna A, Ceccherini-Silberstein F, Cozzi-Lepri A, De Luca A, Gargiulo M, Gervasoni C, Girardi E, Lichtner M, Lo Caputo S, Madeddu G, Maggiolo F, Marcotullio S, Monno L, Murri R, Mussini C, Puoti M, Torti C, Fanti I, Formenti T, Montroni M, Giacometti A, Costantini A, Riva A, Tirelli U, Martellotta F, Ladisa N, Suter F, Verucchi G, Piergentili B, Cristini G, Minardi C, Bertelli D, Quirino T, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Cassola G, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Mastroianni C, Belvisi V, Molteni C, Chiodera A, Castelli P, Rizzardini G, Ridolfo AL, Foschi A, Salpietro S, Merli S, Carenzi L, Moioli MC, Cicconi P, Esposito R, Gori A, Pastore V, Abrescia N, Chirianni A, De Marco M, Ferrari C, Borghi R, Baldelli F, Belfiori B, Parruti G, Sozio F, Magnani G, Ursitti MA, Arlotti M, Ortolani P, Antonucci G, Narciso P, Tozzi V, Vullo V, Zaccarelli M, Gallo L, Acinapura R, De Longis P, Ceccarelli L, Libertone R, Trotta MP, Miccoli A, Cattelan AM, Mura MS, Caramello P, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D, …], DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Facolta' di MEDICINA e CHIRURGIA, and AREA MIN. 06 - Scienze mediche
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microbial ,Male ,Fibrosi ,Lipopolysaccharide Receptors ,HIV Infections ,Kaplan-Meier Estimate ,Liver disease ,Medical microbiology ,Risk Factors ,HIV Infection ,Fib-4 ,Coinfection ,Liver Disease ,Medicine (all) ,Liver Diseases ,virus diseases ,Hepatitis A ,Hepatitis C ,Hepatitis B ,Middle Aged ,sCD14 ,Settore MED/07 - Microbiologia e Microbiologia Clinica ,Infectious Diseases ,Treatment Outcome ,HIV/hepatitis co-infection ,traslocation ,HCV ,HIV ,liver ,Disease Progression ,Biological Markers ,Female ,medicine.symptom ,Adult ,Antigens, CD14 ,CD4 Lymphocyte Count ,Enzyme-Linked Immunosorbent Assay ,Fibrosis ,Humans ,Inflammation ,CD14 ,Microbial translocation ,Research Article ,Human ,medicine.medical_specialty ,Infectious Disease ,Settore MED/17 - MALATTIE INFETTIVE ,Biomarkers ,medicine ,Antigens ,Hepatitis ,business.industry ,Risk Factor ,Biomarker ,medicine.disease ,Virology ,digestive system diseases ,Immunology ,business - Abstract
none 157 no Abstract BACKGROUND: We evaluated whether immune activation (IA) and microbial translocation (MT) might play a role in accelerating liver disease progression in HIV-HBV/HCV co-infected patients. METHODS: ART-naïve HIV/viral hepatitis co-infected patients from Icona with a CD4 cell count >200/μl and with a known date of prior HIV neg/pos tests and ≥1 plasma sample stored were included in the study. Plasma MT (LPS, sCD14) and IA (IL-6,TNFα) were measured using ELISA while activated CD8 + CD38 + HLA-DR + were measured by flow cytometry, with one measurement being performed for all patients and two measurements for a smaller group of subjects. The association between these biomarkers and the time to i) a single ALT >200 IU/l and ii) a Fib-4 >1.45 was also investigated. A standard survival analysis with robust standard errors was used for all evaluations. Follow-up was censored at patients' last clinical follow-up. RESULTS: We studied 127 HIV-infected hepatitis viruses co-infected patients (118 HCV, 9 HBV). Overall median (IQR) CD4, VL, age were 596/μl (208-1303), 3.8 log10cp/mL (3-4.3), 34 years (22-56). While heightened TNF-α was associated with a 13-fold increased risk of Fib-4 > 1.45 (RH 13.05, 95% CI 2.43-70; p = 0.003), markers of MT did not show an association with liver illness. Interestingly, higher sCD14 was associated with a decreased risk of Fib-4 > 1.45, independently of other biomarkers considered (RH 0.20, 95% CI 0.04-0,9; p = 0.04). CONCLUSIONS: In HIV/hepatitis virus co-infected ART-naive patients, higher TNF-α plasma levels were associated with a 13-fold increase in the risk of progression to a Fib-4 >1.45, suggesting that the pro-inflammatory status in HIV infection might hasten the course of HCV. In view of the fact that sCD14 may hinder the interaction between LPS and the phagocyte membrane CD14, we herewith propose a model which aims to demonstrate that high sCD14 levels might contribute to shelter liver function through the down-regulation of the inflammatory cascade. Marchetti, Giulia; Cozzi-Lepri, Alessandro; Tincati, Camilla; Calcagno, Andrea; Ceccherini-Silberstein, Francesca; De Luca, Andrea; Antinori, Andrea; Castagna, Antonella; Puoti, Massimo; Monforte, Antonella d'Arminio; and for the Icona Foundation Study Group […; Moroni M; Angarano G; Antinori A; Carosi G; Cauda R; Monforte A; Di Perri G; Galli M; Iardino R; Ippolito G; Lazzarin A; Perno CF; Viale PL; Von Schlosser F; Monforte Ad; Ammassari A; Andreoni M; Antinori A; Balotta C; Bonfanti P; Bonora S; Borderi M; Capobianchi MR; Castagna A; Ceccherini-Silberstein F; Cozzi-Lepri A; Monforte A; De Luca A; Gargiulo M; Gervasoni C; Girardi E; Lichtner M; Lo Caputo S; Madeddu G; Maggiolo F; Marcotullio S; Monno L; Murri R; Mussini C; Puoti M; Torti C; Cozzi-Lepri A; Fanti I; Formenti T; Montroni M; Giacometti A; Costantini A; Riva A; Tirelli U; Martellotta F; Angarano G; Monno L; Ladisa N; Suter F; Maggiolo F; Viale PL; Verucchi G; Piergentili B; Carosi G; Cristini G; Torti C; Minardi C; Bertelli D; Quirino T; Abeli C; Manconi PE; Piano P; Vecchiet J; Falasca K; Carnevale G; Lorenzotti S; Sighinolfi L; Leoncini F; Mazzotta F; Pozzi M; Lo Caputo S; Cassola G; Viscoli G; Alessandrini A; Piscopo R; Mazzarello G; Mastroianni C; Belvisi V; Bonfanti P; Molteni C; Chiodera A; Castelli P; Galli M; Lazzarin A; Rizzardini G; Puoti M; Monforte A; Ridolfo AL; Foschi A; Castagna A; Salpietro S; Merli S; Carenzi L; Moioli MC; Cicconi P; Formenti T; Esposito R; Mussini C; Gori A; Pastore V; Abrescia N; Chirianni A; De Marco M; Ferrari C; Borghi R; Baldelli F; Belfiori B; Parruti G; Sozio F; Magnani G; Ursitti MA; Arlotti M; Ortolani P; Cauda R; Andreoni M; Antinori A; Antonucci G; Narciso P; Tozzi V; Vullo V; De Luca A; Zaccarelli M; Gallo L; Acinapura R; De Longis P; Ceccarelli L; Libertone R; Trotta MP; Miccoli A; Cattelan AM; Mura MS; Madeddu G; Caramello P; Di Perri G; Orofino GC; Sciandra M; Raise E; Ebo F; Pellizzer G; Buonfrate D; …] Marchetti, Giulia; Cozzi-Lepri, Alessandro; Tincati, Camilla; Calcagno, Andrea; Ceccherini-Silberstein, Francesca; De Luca, Andrea; Antinori, Andrea; Castagna, Antonella; Puoti, Massimo; Monforte, Antonella d'Arminio; and for the Icona Foundation Study Group […; Moroni M; Angarano G; Antinori A; Carosi G; Cauda R; Monforte A; Di Perri G; Galli M; Iardino R; Ippolito G; Lazzarin A; Perno CF; Viale PL; Von Schlosser F; Monforte Ad; Ammassari A; Andreoni M; Antinori A; Balotta C; Bonfanti P; Bonora S; Borderi M; Capobianchi MR; Castagna A; Ceccherini-Silberstein F; Cozzi-Lepri A; Monforte A; De Luca A; Gargiulo M; Gervasoni C; Girardi E; Lichtner M; Lo Caputo S; Madeddu G; Maggiolo F; Marcotullio S; Monno L; Murri R; Mussini C; Puoti M; Torti C; Cozzi-Lepri A; Fanti I; Formenti T; Montroni M; Giacometti A; Costantini A; Riva A; Tirelli U; Martellotta F; Angarano G; Monno L; Ladisa N; Suter F; Maggiolo F; Viale PL; Verucchi G; Piergentili B; Carosi G; Cristini G; Torti C; Minardi C; Bertelli D; Quirino T; Abeli C; Manconi PE; Piano P; Vecchiet J; Falasca K; Carnevale G; Lorenzotti S; Sighinolfi L; Leoncini F; Mazzotta F; Pozzi M; Lo Caputo S; Cassola G; Viscoli G; Alessandrini A; Piscopo R; Mazzarello G; Mastroianni C; Belvisi V; Bonfanti P; Molteni C; Chiodera A; Castelli P; Galli M; Lazzarin A; Rizzardini G; Puoti M; Monforte A; Ridolfo AL; Foschi A; Castagna A; Salpietro S; Merli S; Carenzi L; Moioli MC; Cicconi P; Formenti T; Esposito R; Mussini C; Gori A; Pastore V; Abrescia N; Chirianni A; De Marco M; Ferrari C; Borghi R; Baldelli F; Belfiori B; Parruti G; Sozio F; Magnani G; Ursitti MA; Arlotti M; Ortolani P; Cauda R; Andreoni M; Antinori A; Antonucci G; Narciso P; Tozzi V; Vullo V; De Luca A; Zaccarelli M; Gallo L; Acinapura R; De Longis P; Ceccarelli L; Libertone R; Trotta MP; Miccoli A; Cattelan AM; Mura MS; Madeddu G; Caramello P; Di Perri G; Orofino GC; Sciandra M; Raise E; Ebo F; Pellizzer G; Buonfrate D; …]
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- 2014
9. Linee Guida per la diagnosi e terapia dell’Immunodeficienza Comune Variabile
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Aiuti F., Aiuti A., Calza l., Chiodo F., De Santis W., D’Ettore G., Emmi L., Isgrò A., Luzi G., Maggi E., Marziali M., Mezzaroma I., Montroni M., Muscaritoli M., Paganelli R., Pandolfi F., Starnino S., Sirianni M. C., SPADARO, GIUSEPPE, Vullo V., Aiuti, F, Aiuti, Alessandro, Calza, L, Chiodo, F, DE SANTIS, W, Dettorre, G, Emmi, L, Isgrò, A, Luzi, G, Maggi, E, Marziali, M, Mezzaroma, I, Montroni, M, Muscaritoli, M, Paganelli, R, Pandolfi, F, Starnino, S, SIRIANNI M., C, Spadarò, G, Vullo, V., Aiuti, F., Aiuti, A., Calza, L., Chiodo, F., De Santis, W., D’Ettore, G., Emmi, L., Isgrò, A., Luzi, G., Maggi, E., Marziali, M., Mezzaroma, I., Montroni, M., Muscaritoli, M., Paganelli, R., Pandolfi, F., Starnino, S., Sirianni, M. C., and Spadaro, Giuseppe
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- 2006
10. Antiretroviral genotypic resistance in plasma RNA and whole blood DNA in HIV-1 infected patients failing HAART
- Author
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Saracino, A, Gianotti, N, Marangi, M, Cibelli, Dc, Galli, A, Punzi, G, Monno, L, Lazzarin, A, Angarano, G, Dini, M, Del Gobbo, R, Montroni, M, Butini, L, Scalise, G, Ancarani, F, Di Cesare, S, Giacometti, A, Biglino, A, Degioanni, M, Paoloni, M, Mariani, R, Calella, G, Pastore, G, Ladisa, N, Mennea, G, Gritti, Fm, Fasullo, G, Chiodo, F, Borderi, M, Carosi, Giampiero, Castelli, Francesco, Torti, Carlo, Uccelli, C, Rizzardini, G, Visoná, R, Salvo, A, Averna, A, Russo, R, Celesia, Bm, Cosentino, S, Rinaldi, E, Pusterla, L, Carnevale, G, Mondello, P, Petrini, C, Ghinelli, F, Sighinolfi, L, Mazzotta, F, Lo Caputo, S, Pierotti, P, Leoncini, F, Sterrantino, Gk, Corsi, P, Pompei, Ag, Di Toro MT, Purificato, F, Indiveri, F, Setti, M, Murdaca, G, Iannessi, A, Cellini, A, Mariani, A, Scasso, A, De Gennaro, M, Chiodera, A, Castelli, P, Maltempo, K, Mongolo, G, Caggese, L, Schlacht, I, Cargnel, A, Atzori, C, Micheli, V, Moroni, M, Bini, T, Marcatto, I, Chiesa, E, Vigevani, G, Argenteri, B, Capetti, A, Esposito, R, Guaraldi, G, Seghetto, B, Chirianni, A, Gargiulo, M, Abrescia, N, D'Abbraccio, M, Busto, T, Marchitelli, C, Santirocchi, M, Abbadessa, V, Mancuso, S, Meneghetti, F, Pranzetti, M, Ferrari, C, Pizzaferri, P, Stagni, G, Di Candilo, F, Petrelli, E, Balducci, M, Menichetti, F, Polidori, M, Tascini, C, Di Carlo, A, Palamara, G, Antinori, A, Liuzzi, G, Aiuti, F, Mezzaroma, I, Pinter, E, Barbone, B, Vullo, V, Massetti, P, Dell'Isola, S, Mura, Ms, Mannazzu, M, Delias, R, Di Giammartino, D, Tarquini, P, Marranconi, F, Ferretto, R, Caramello, P, Orofino, Gc, Cimino, T, Bramato, C, Di Perri, G, Sinicco, A, Zeme, D, Bonora, S, Trentini, L, Soranzo, Ml, Macor, A, Salassa, B, Branz, F, Delle Foglie, P, Vaglia, A, Rossi, Mc, Ciccone, L, Panzolli, L, Grossi, P, Giola, M, Raise, E, Narne, E, Poggio, A, Demin, F, Mondino, V, Serpelloni, G, Malena, M, Bosco, O., Saracino, A, Gianotti, N, Marangi, M, Cibelli, D, Galli, A, Punzi, G, Monno, L, Lazzarin, A, Angarano, G, and Mancuso, S
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Anti-HIV Agents ,DNA Mutational Analysis ,Molecular Sequence Data ,Proviral DNA ,HIV Infections ,HAART failure ,medicine.disease_cause ,DNA Mutational Analysi ,chemistry.chemical_compound ,HIV Protease ,Proviruses ,Antiretroviral Therapy, Highly Active ,Virology ,Drug Resistance, Viral ,medicine ,Humans ,Multicenter Studies as Topic ,HIV Infection ,Treatment Failure ,Genotyping ,Randomized Controlled Trials as Topic ,COLD-PCR ,Mutation ,Plasma RNA ,biology ,Proviruse ,Sequence Analysis, RNA ,Anti-HIV Agent ,RNA ,Sequence Analysis, DNA ,biology.organism_classification ,HIV Reverse Transcriptase ,Reverse transcriptase ,Antiretroviral genotypic resistance ,Infectious Diseases ,chemistry ,DNA, Viral ,Lentivirus ,Immunology ,HIV-1 ,RNA, Viral ,DNA ,antiretroviral genotypic resistance ,haart failure ,hiv-1 ,plasma rna ,proviral dna ,Human - Abstract
The extent to which HIV-1 proviral DNA mutations cause clinically relevant antiretroviral resistance is still controversial. Paired plasma HIV-1 RNA and whole blood DNA were compared in patients failing HAART to investigate if the additional knowledge of archived mutations could improve the selection of potentially active drugs. Seventy-three HIV-1-infected patients with first/second HAART failure were studied before starting a new regimen based on RNA genotyping. Follow-up data after a 12-week therapy were available. DNA genotyping was retrospectively performed on stored whole blood samples and mutational profiles were compared to those from RNA. The mean number of IAS pol mutations was significantly higher in RNA (4.45 ± 2.76) than in DNA (2.88 ± 2.47) (P < 0.001). DNA genotyping provided a 6% increase in detection of resistance-associated mutations. Among 64/73 patients showing discordant DNA/RNA profiles, 54 (84%) also differed for predicted active drugs. 16/73 (22%) patients had ≥1 mutation revealed by DNA genotyping alone, probably affecting therapy success in 2/16. However, neither RNA/DNA discordance nor detection of isolated DNA mutations were statistically associated with outcome. In conclusion, plasma RNA remains the elective choice for HIV genotyping in patients with therapy failure, even if the detection of proviral resistance-associated mutations, not simultaneously found in RNA, is a frequent event. Therefore, in some cases DNA plus RNA genotyping might assist in choosing more accurately subsequent antiretroviral regimens. © 2008 Wiley-Liss, Inc.
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- 2008
11. Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study
- Author
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Murray, D. D., Suzuki, K., Law, M., Trebicka, J., Neuhaus, J., Wentworth, D., Johnson, M., Vjecha, M. J., Kelleher, A. D., Emery, S., Aagaard, B., Aragon, E., Arnaiz, J., Borup, L., Clotet, B., Dragsted, U., Fau, A., Gey, D., Grarup, J., Hengge, U., Herrero, P., Jansson, P., Jensen, B., Jensen, K., Juncher, H., Lopez, P., Lundgren, J. D., Matthews, C., Mollerup, D., Pearson, M., Phillips, A., Reilev, S., Tillmann, K., Varea, S., Angus, B., Babiker, A., Cordwell, B., Darbyshire, J., Dodds, W., Fleck, S., Horton, J., Hudson, F., Moraes, Y., Pacciarini, F., Palfreeman, A., Paton, N., Smith, N., Van Hooff, F., Bebchuk, J., Collins, G., Denning, E., Duchene, A., Fosdick, L., Harrison, M., Herman-Lamin, K., Krum, E., Larson, G., Neaton, J., Nelson, R., Quan, K., Quan, S., Schultz, T., Thompson, G., Wyman, N., Carey, C., Chan, F., Cooper, D., Courtney-Rodgers, D., Drummond, F., Harrod, M., Jacoby, S., Kearney, L., Lin, E., Pett, S., Robson, R., Seneviratne, N., Stewart, M., Watts, E., Finley, E., Gordin, F., Sanchez, A., Standridge, B., Belloso, W., Davey, R., Duprez, D., Gatell, J., Hoy, J., Lifson, A., Pederson, C., Perez, G., Price, R., Prineas, R., Rhame, F., Sampson, J., Worley, J., Modlin, J., Beral, V., Chaisson, R., Fleming, T., Hill, C., Kim, K., Murray, B., Pick, B., Seligmann, M., Weller, I., Cahill, K., Fox, L., Luzar, M., Martinez, A., Mcnay, L., Pierson, J., Tierney, J., Vogel, S., Costas, V., Eckstrand, J., Brown, S., Abusamra, L., Angel, E., Aquilia, S., Benetucci, J., Bittar, V., Bogdanowicz, E., Cahn, P., Casiro, A., Contarelli, J., Corral, J., Daciuk, L., David, D., Dobrzanski, W., Duran, A., Ebenrstejin, J., Ferrari, I., Fridman, D., Galache, V., Guaragna, G., Ivalo, S., Krolewiecki, A., Lanusse, I., Laplume, H., Lasala, M., Lattes, R., Lazovski, J., Lopardo, G., Losso, M., Lourtau, L., Lupo, S., Maranzana, A., Marson, C., Massera, L., Moscatello, G., Olivia, S., Otegui, I., Palacios, L., Parlante, A., Salomon, H., Sanchez, M., Somenzini, C., Suarez, C., Tocci, M., Toibaro, J., Zala, C., Agrawal, S., Ambrose, P., Anderson, C., Anderson, J., Baker, D., Beileiter, K., Blavius, K., Bloch, M., Boyle, M., Bradford, D., Britton, P., Brown, P., Busic, T., Cain, A., Carrall, L., Carson, S., Chenoweth, I., Chuah, J., Clark, F., Clemons, J., Clezy, K., Cortissos, P., Cunningham, N., Curry, M., Daly, L., D'Arcy-Evans, C., Del Rosario, R., Dinning, S., Dobson, P., Donohue, W., Doong, N., Downs, C., Edwards, E., Edwards, S., Egan, C., Ferguson, W., Finlayson, R., Forsdyke, C., Foy, L., Franic, T., Frater, A., French, M., Gleeson, D., Gold, J., Habel, P., Haig, K., Hardy, S., Holland, R., Hudson, J., Hutchison, R., Hyland, N., James, R., Johnston, C., Kelly, M., King, M., Kunkel, K., Lau, H., Leamy, J., Lester, D., Leung, J., Lohmeyer, A., Lowe, K., Macrae, K., Magness, C., Martinez, O., Maruszak, H., Medland, N., Miller, S., Murray, J., Negus, P., Newman, R., Ngieng, M., Nowlan, C., Oddy, J., Orford, N., Orth, D., Patching, J., Plummer, M., Price, S., Primrose, R., Prone, I., Ree, H., Remington, C., Richardson, R., Robinson, S., Rogers, G., Roney, J., Roth, N., Russell, D., Ryan, S., Sarangapany, J., Schmidt, T., Schneider, K., Shields, C., Silberberg, C., Shaw, D., Skett, J., Smith, D., Soo, T. M., Sowden, D., Street, A., Tee, B. K., Thomson, J., Topaz, S., Vale, R., Villella, C., Walker, A., Watson, A., Wendt, N., Williams, L., Youds, D., Aichelburg, A., Cichon, P., Gemeinhart, B., Rieger, A., Schmied, B., Touzeau-Romer, V., Vetter, N., Colebunders, R., Clumeck, N., Deroo, A., Kabeya, K., O'Doherty, E., De Wit, S., De Salles Amorim, C., Basso, C., Flint, S., Kallas, E., Levi, G., Lewi, D., Pereira, L., Da Silva, M., Souza, T., Toscano, A., Angel, J., Arsenault, M., Bast, M., Beckthold, B., Bouchard, P., Chabot, I., Clarke, R., Cohen, J., Cote, P., Ellis, M., Gagne, C., Gill, J., Houde, M., Johnston, B., Jubinville, N., Kato, C., Lamoureux, N., Latendre-Paquette, J., Lindemulder, A., Mcneil, A., Mcfarland, N., Montaner, J., Morrisseau, C., O'Neill, R., Page, G., Piche, A., Pongracz, B., Preziosi, H., Puri, L., Rachlis, A., Ralph, E., Raymond, I., Rouleau, D., Routy, J. P., Sandre, R., Seddon, T., Shafran, S., Sikora, C., Smaill, F., Stromberg, D., Trottier, S., Walmsley, S., Weiss, K., Williams, K., Zarowny, D., Baadegaard, B., Andersen, A. B., Boedker, K., Collins, P., Gerstoft, J., Jensen, L., Moller, H., Andersen, P. L., Loftheim, I., Mathiesen, L., Nielsen, H., Obel, N., Pedersen, C., Petersen, D., Jensen, L. P., Black, F. T., Aboulker, J. P., Aouba, A., Bensalem, M., Berthe, H., Blanc, C., Bornarel, D., Bouchaud, O., Boue, F., Bouvet, E., Brancon, C., Breaud, S., Brosseau, D., Brunet, A., Capitant, C., Ceppi, C., Chakvetadze, C., Cheneau, C., Chennebault, J. M., De Truchis, P., Delavalle, A. M., Delfraissy, J. F., Dellamonica, P., Dumont, C., Edeb, N., Fabre, G., Ferrando, S., Foltzer, A., Foubert, V., Gastaut, J. A., Gerbe, J., Girard, P. M., Goujard, C., Hoen, B., Honore, P., Hue, H., Hynh, T., Jung, C., Kahi, S., Katlama, C., Lang, J. M., Le Baut, V., Lefebvre, B., Leturque, N., Levy, Y., Loison, J., Maddi, G., Maignan, A., Majerholc, C., De Boever, C., Meynard, J. L., Michelet, C., Michon, C., Mole, M., Netzer, E., Pialoux, G., Poizot-Martin, I., Raffi, F., Ratajczak, M., Ravaux, I., Reynes, J., Salmon-Ceron, D., Sebire, M., Simon, A., Tegna, L., Tisne-Dessus, D., Tramoni, C., Viard, J. P., Vidal, M., Viet-Peaucelle, C., Weiss, L., Zeng, A., Zucman, D., Adam, A., Arasteh, K., Behrens, G., Bergmann, F., Bickel, M., Bittner, D., Bogner, J., Brockmeyer, N., Darrelmann, N., Deja, M., Doerler, M., Esser, S., Faetkenheuer, G., Fenske, S., Gajetzki, S., Goebel, F., Gorriahn, D., Harrer, E., Harrer, T., Hartl, H., Hartmann, M., Heesch, S., Jakob, W., Jager, H., Klinker, H., Kremer, G., Ludwig, C., Mantzsch, K., Mauss, S., Meurer, A., Niedermeier, A., Pittack, N., Plettenberg, A., Potthoff, A., Probst, M., Rittweger, M., Rockstroh, J., Ross, B., Rotty, J., Rund, E., Ruzicka, T., Schmidt, R., Schmutz, G., Schnaitmann, E., Schuster, D., Sehr, T., Spaeth, B., Staszewski, S., Stellbrink, H. J., Stephan, C., Stockey, T., Stoehr, A., Trein, A., Vaeth, T., Vogel, M., Wasmuth, J., Wengenroth, C., Winzer, R., Wolf, E., Mulcahy, F., Reidy, D., Cohen, Y., Drora, G., Eliezer, I., Godo, O., Kedem, E., Magen, E., Mamorsky, M., Pollack, S., Sthoeger, Z., Vered, H., Yust, I., Aiuti, F., Bechi, M., Bergamasco, A., Bertelli, D., Bruno, R., Butini, L., Cagliuso, M., Carosi, G., Casari, S., Chrysoula, V., Cologni, G., Conti, V., Costantini, A., Corpolongo, A., D'Offizi, G., Gaiottino, F., Di Pietro, M., Esposito, R., Filice, G., Francesco, M., Gianelli, E., Graziella, C., Magenta, L., Martellotta, F., Maserati, R., Mazzotta, F., Murdaca, G., Nardini, G., Nozza, S., Puppo, F., Pogliaghi, M., Ripamonti, D., Ronchetti, C., Rusconi, S., Rusconi, V., Sacchi, P., Silvia, N., Suter, F., Tambussi, G., Uglietti, A., Vechi, M., Vergani, B., Vichi, F., Vitiello, P., Iwamoto, A., Kikuchi, Y., Miyazaki, N., Mori, M., Nakamura, T., Odawara, T., Oka, S., Shirasaka, T., Tabata, M., Takano, M., Ueta, C., Watanabe, D., Yamamoto, Y., Erradey, I., Himmich, H., El Filali, K. M., Blok, W., Van Boxtel, R., Doevelaar, K. B. H., Van Eeden, A., Grijsen, M., Groot, M., Juttmann, J., Kuipers, M., Ligthart, S., Van Der Meulen, P., Lange, J., Langebeek, N., Reiss, P., Richter, C., Schoemaker, M., Schrijnders-Gudde, L., Septer-Bijleveld, E., Sprenger, H., Vermeulen, J., Ten Kate, R., Van De Ven, B., Bruun, J., Kvale, D., Maeland, A., Bakowska, E., Beniowski, M., Boron-Kaczmarska, A., Gasiorowski, J., Horban, A., Inglot, M., Knysz, B., Mularska, E., Parczewski, M., Pynka, M., Rymer, W., Szymczak, A., Aldir, M., Antunes, F., Baptista, C., Da Conceicao Vera, J., Doroana, M., Mansinho, K., Dos Santos, C. R. A., Valadas, E., Vaz Pinto, I., Chia, E., Foo, E., Karim, F., Lim, P. L., Panchalingam, A., Quek, A., Alcazar-Caballero, R., Arribas, J., Arrizabalaga, J., De Barron, X., Blanco, F., Bouza, E., Bravo, I., Calvo, S., Carbonero, L., Carpena, I., Castro, M., Cortes, L., Del Toro, M., Domingo, P., Elias, M., Espinosa, J., Estrada, V., Fernandez-Cruz, E., Fernandez, P., Freud, H., Fuster, M., Garcia, A., Garcia, G., Garrido, R., Gijon, P., Gonzalez-Garcia, J., Gil, I., Gonzalez, A., Gonzalez-Lahoz, J., Grosso, P. L., Gutierrez, M., Guzman, E., Iribarren, J., Jimenez, M., Jou, A., Juega, J., Lopez, J., Lozano, F., Martin-Carbonero, L., Mata, R., Mateo, G., Menasalvas, A., Mirelles, C., De Miguel Prieto, J., Montes, M., Moreno, A., Moreno, J., Moreno, V., Munoz, R., Ocampo, A., Ortega, E., Ortiz, L., Padilla, B., Parras, A., Paster, A., Pedreira, J., Pena, J., Perea, R., Portas, B., Puig, J., Pulido, F., Rebollar, M., De Rivera, J., Roca, V., Rodriguez-Arrondo, F., Rubio, R., Santos, J., Sanz, J., Sebastian, G., Segovia, M., Soriano, V., Tamargo, L., Viciana, P., Von Wichmann, M., Bratt, G., Hollander, A., Olov Pehrson, P., Petz, I., Sandstrom, E., Sonnerborg, A., Bernasconi, E., Gurtner, V., Ampunpong, U., Auchieng, C., Bowonwatanuwong, C., Chanchai, P., Chetchotisakd, P., Chuenyan, T., Duncombe, C., Horsakulthai, M., Kantipong, P., Laohajinda, K., Phanuphak, P., Pongsurachet, V., Pradapmook, S., Ruxruntham, K., Seekaew, S., Sonjai, A., Suwanagool, S., Techasathit, W., Ubolyam, S., Wankoon, J., Alexander, I., Dockrell, D., Easterbrook, P., Edwards, B., Evans, E., Fisher, M., Fox, R., Gazzard, B., Gilleran, G., Hand, J., Heald, L., Higgs, C., Jebakumar, S., Jendrulek, I., Johnson, S., Kinghorn, G., Kuldanek, K., Leen, C., Maw, R., Mckernan, S., Mclean, L., Morris, S., Murphy, M., O'Farrell, S., Ong, E., Peters, B., Stroud, C., Wansbrough-Jones, M., Weber, J., White, D., Williams, I., Wiselka, M., Yee, T., Adams, S., Allegra, D., Andrews, L., Aneja, B., Anstead, G., Arduino, R., Artz, R., Bailowitz, J., Banks, S., Baxter, J., Baum, J., Benator, D., Black, D., Boh, D., Bonam, T., Brito, M., Brockelman, J., Bruzzese, V., Burnside, A., Cafaro, V., Casey, K., Cason, L., Childress, G., Clark, C., Clifford, D., Climo, M., Cohn, D., Couey, P., Cuervo, H., Deeks, S., Dennis, M., Diaz-Linares, M., Dickerson, D., Diez, M., Di Puppo, J., Dodson, P., Dupre, D., Elion, R., Elliott, K., El-Sadr, W., Estes, M., Fabre, J., Farrough, M., Flamm, J., Follansbee, S., Foster, C., Frank, C., Franz, J., Frechette, G., Freidland, G., Frische, J., Fuentes, L., Funk, C., Geisler, C., Genther, K., Giles, M., Goetz, M., Gonzalez, M., Graeber, C., Graziano, F., Grice, D., Hahn, B., Hamilton, C., Hassler, S., Henson, A., Hopper, S., John, M., Johnson, L., Johnson, R., Jones, R., Kahn, J., Klimas, N., Kolber, M., Koletar, S., Labriola, A., Larsen, R., Lasseter, F., Lederman, M., Ling, T., Lusch, T., Macarthur, R., Machado, C., Makohon, L., Mandelke, J., Mannheimer, S., Markowitz, N., Martinez, M., Martinez, N., Mass, M., Masur, H., Mcgregor, D., Mcintyre, D., Mckee, J., Mcmullen, D., Mettinger, M., Middleton, S., Mieras, J., Mildvan, D., Miller, P., Miller, T., Mitchell, V., Mitsuyasu, R., Moanna, A., Mogridge, C., Moran, F., Murphy, R., Mushatt, D., Nahass, R., Nixon, D., O'Brien, S., Ojeda, J., Okhuysen, P., Olson, M., Osterberger, J., Owen, W., Pablovich, S., Patel, S., Pierone, G., Poblete, R., Potter, A., Preston, E., Rappoport, C., Regevik, N., Reyelt, M., Riney, L., Rodriguez-Barradas, M., Rodriguez, J., Roland, R., Rosmarin-DeStefano, C., Rossen, W., Rouff, J., Saag, M., Santiago, S., Sarria, J., Wirtz, S., Schmidt, U., Scott, C., Sheridan, A., Shin, A., Shrader, S., Simon, G., Slowinski, D., Smith, K., Spotkov, J., Sprague, C., States, D., Suh, C., Sullivan, J., Summers, K., Sweeton, B., Tan, V., Tanner, T., Tedaldi, E., Temesgen, Z., Thomas, D., Thompson, M., Tobin, C., Toro, N., Towner, W., Upton, K., Uy, J., Valenti, S., Van Der Horst, C., Vita, J., Voell, J., Walker, J., Walton, T., Wason, K., Watson, V., Wellons, A., Weise, J., White, M., Whitman, T., Williams, B., Williams, N., Windham, J., Witt, M., Workowski, K., Wortmann, G., Wright, T., Zelasky, C., Zwickl, B., Dietz, D., Chesson, C., Vjecha, M., Schmetter, B., Grue, L., Willoughby, M., Demers, A., Dragsted, U. B., Jensen, K. B., Jansson, P. O., Jensen, B. G., Benfield, T. L., Darbyshire, J. H., Babiker, G., Fleck, S. L., Collaco-Moraes, Y., Wyzydrag, L., Drummond, F. M., Connor, S. A., Satchell, C. S., Gunn, S., Delfino, M. A., Merlin, K., Mcginley, C., Neaton, J. D., Bartsch, G., George, M., Grund, B., Hogan, C., Miller, C., Roediger, M. P., Thackeray, L., Campbell, C., Lahart, C., Perlman, D., Rein, M., Dersimonian, R., Brody, B. A., Daar, E. S., Dubler, N. N., Fleming, T. R., Freeman, D. J., Kahn, J. P., Kim, K. M., Medoff, G., Modlin, J. F., Moellering, R., Murray, B. E., Robb, M. L., Scharfstein, D. O., Sugarman, J., Tsiatis, A., Tuazon, C., Zoloth, L., Klingman, K., Lehrman, S., Belloso, W. H., Losso, M. H., Benetucci, J. A., Bogdanowicz, E. P., Cahn, P. E., Casiro, A. D., Cassetti, I., Contarelli, J. M., Corral, J. A., Crinejo, A., David, D. O., Ishida, M. T., Laplume, H. E., Lasala, M. B., Lupo, S. H., Masciottra, F., Michaan, M., Ruggieri, L., Salazar, E., Hoy, J. F., Rogers, G. D., Allworth, A. M., Anderson, J. S. C., Armishaw, J., Barnes, K., Carr, A., Chiam, A., Chuah, J. C. P., Curry, M. C., Dever, R. L., Donohue, W. A., Doong, N. C., Dwyer, D. E., Dyer, J., Eu, B., Ferguson, V. W., French, M. A. H., Garsia, R. J., Hudson, J. H., Jeganathan, S., Konecny, P., Mccormack, C. L., Mcmurchie, M., Moore, R. J., Moussa, M. B., Piper, M., Read, T., Roney, J. J., Shaw, D. R., Silvers, J., Smith, D. J., Street, A. C., Vale, R. J., Wendt, N. A., Wood, H., Youds, D. W., Zillman, J., Tozeau, V., Dewit, S., De Roo, A., Leonard, P., Lynen, L., Moutschen, M., Pereira, L. C., Souza, T. N. L., Schechter, M., Zajdenverg, R., Almeida, M. M. T. B., Araujo, F., Bahia, F., Brites, C., Caseiro, M. M., Casseb, J., Etzel, A., Falco, G. G., Filho, E. C. J., Flint, S. R., Gonzales, R., Madruga, J. V. R., Passos, L. N., Reuter, T., Sidi, L. C., Toscano, A. L. C., Cherban, E., Conway, B., Dufour, C., Foster, A., Haase, D., Haldane, H., Klein, M., Lessard, B., Martel, A., Martel, C., Paradis, E., Schlech, W., Schmidt, S., Thompson, B., Vezina, S., Reyes, M. J. W., Northland, R., Ostergaard, L., Hergens, L., Loftheim, I. R., Raukas, M., Zilmer, K., Justinen, J., Ristola, M., Landman, R., Abel, S., Abgrall, S., Amat, K., Auperin, L., Barruet, R., Benalycherif, A., Benammar, N., Bentata, M., Besnier, J. M., Blanc, M., Cabie, A., Chavannet, P., Dargere, S., De La Tribonniere, X., Debord, T., Decaux, N., Delgado, J., Dupon, M., Durant, J., Frixon-Marin, V., Genet, C., Gerard, L., Gilquin, J., Jeantils, V., Kouadio, H., Leclercq, P., Lelievre, J. D., Michon, C. P., Nau, P., Pacanowski, J., Piketty, C., Salmon, D., Schmit, J. L., Serini, M. A., Tassi, S., Touam, F., Verdon, R., Weinbreck, P., Yazdanpanah, Y., Yeni, P., Fatkenheuer, G., Bitsch, S., Bogner, J. R., Goebel, F. D., Lehmann, C., Lennemann, T., Wasmuth, J. C., Wiedemeyer, K., Hatzakis, A., Touloumi, G., Antoniadou, A., Daikos, G. L., Dimitrakaki, A., Gargalianos-Kakolyris, P., Giannaris, M., Karafoulidou, A., Katsambas, A., Katsarou, O., Kontos, A. N., Kordossis, T., Lazanas, M. K., Panagopoulos, P., Panos, G., Paparizos, V., Papastamopoulos, V., Petrikkos, G., Sambatakou, H., Skoutelis, A., Tsogas, N., Xylomenos, G., Bergin, C. J., Mooka, B., Mamorksy, M. G., Agmon-Levin, N., Karplus, R., Maayan, S., Shahar, E., Turner, D., Abeli, C., Biglino, A., Bonora, S., De Gioanni, M., Di Perri, G., Montroni, M., Quirino, T., Raise, E., Honda, M., Ishisaka, M., Caplinskas, S., Uzdaviniene, V., Schmit, J. C., Staub, T., Mills, G. D., Blackmore, T., Masters, J. A., Morgan, J., Pithie, A., Brunn, J., Ormassen, V., La Rosa, A., Guerra, O., Espichan, M., Gutierrez, L., Mendo, F., Salazar, R., Knytz, B., Kwiatkowski, J., Castro, R. S., Horta, A., Miranda, A. C., Pinto, I. V., Vera, J., Rakhmanova, A., Vinogradova, E., Yakovlev, A., Zakharova, N., Wood, R., Orrel, C., Arnaiz, J. A., Carrillo, R., Dalmau, D., Jordano, Q., Knobel, H., Larrousse, M., Moreno, J. S., Oretaga, E., Pena, J. N., Hirschel, B., Spycher, R., Battegay, M., Bottone, S., Cavassini, M., Christen, A., Furrer, H. J., Gayet-Ageron, A., Genne, D., Hochstrasser, S., Moens, C., Muller, N., Nuesch, R., Ruxrungtham, K., Pumpradit, W., Dangthongdee, S., Kiertiburanakul, S., Klinbuayaem, V., Mootsikapun, P., Nonenoy, S., Piyavong, B., Prasithsirikul, W., Raksakulkarn, P., Gazzard, B. G., Ainsworth, J. G., Angus, B. J., Barber, T. J., Brook, M. G., Care, C. D., Chadwick, D. R., Chikohora, M., Churchill, D. R., Cornforth, D., Dockrell, D. H., Easterbrook, P. J., Fox, P. A., Gomez, P. A., Gompels, M. M., Harris, G. M., Herman, S., Jackson, A. G. A., Jebakumar, S. P. R., Kinghorn, G. R., Kuldanek, K. A., Larbalestier, N., Lumsden, M., Maher, T., Mantell, J., Muromba, L., Orkin, C. M., Peters, S., Peto, T. E. A., Portsmouth, S. D., Rajamanoharan, S., Ronan, Schwenk, A., Slinn, M. A., Stroud, C. J., Thomas, R. C., Wansbrough-Jones, M. H., Whiles, H. J., White, D. J., Williams, E., Williams, G., Youle, M., Abrams, D. I., Acosta, E. A., Adamski, A., Antoniskis, D., Aragon, D. R., Barnett, B. J., Baroni, C., Barron, M., Baxter, J. D., Beers, D., Beilke, M., Bemenderfer, Bernard, A., Besch, C. L., Bessesen, M. T., Bethel, J. T., Blue, S., Blum, J. D., Boarden, S., Bolan, R. K., Borgman, J. B., Brar, I., Braxton, B. K., Bredeek, U. F., Brennan, R., Britt, D. E., Bulgin-Coleman, D., Bullock, E., Campbell, B., Caras, S., Carroll, J., Casey, K. K., Chiang, F., Cindrich, R. B., Cohen, C., Coley, J., Condoluci, D. V., Contreras, R., Corser, J., Cozzolino, J., Crane, L. R., Daley, L., Dandridge, D., D'Antuono, V., Darcourt Rizo Patron, J. G., Dehovitz, J. A., Dejesus, E., Desjardin, J., Dietrich, C., Dolce, A., Erickson, D., Faber, L. L., Falbo, J., Farrough, M. J., Farthing, C. F., Ferrell-Gonzalez, P., Flynn, H., Frank, M., Freeman, K. F., French, N., Friedland, G., Fujita, N., Gahagan, L., Gilson, I., Goetz, M. B., Goodwin, E., Guity, C. K., Gulick, P., Gunderson, E. R., Hale, C. M., Hannah, K., Henderson, H., Hennessey, K., Henry, W. K., Higgins, T., Hodder, S. L., Horowitz, H. W., Howe-Pittman, M., Hubbard, J., Hudson, R., Hunter, H., Hutelmyer, C., Insignares, M. T., Jackson, L., Jenny, L., Johnson, D. L., Johnson, G., Johnson, J., Kaatz, J., Kaczmarski, J., Kagan, S., Kantor, C., Kempner, T., Kieckhaus, K., Kimmel, N., Klaus, B. M., Koeppe, J. R., Koirala, J., Kopka, J., Kostman, J. R., Kozal, M. J., Kumar, A., Lampiris, H., Lamprecht, C., Lattanzi, K. M., Lee, J., Leggett, J., Long, C., Loquere, A., Loveless, K., Lucasti, C. J., Luskin-Hawk, R., Macveigh, M., Makohon, L. H., Markowitz, N. P., Marks, C., Martorell, C., Mcfeaters, E., Mcgee, B., Mcintyre, D. M., Mcmanus, E., Melecio, L. G., Melton, D., Mercado, S., Merrifield, E., Mieras, J. A., Mogyoros, M., Moran, F. M., Murphy, K., Mutic, S., Nadeem, I., Nadler, J. P., Ognjan, A., O'Hearn, M., O'Keefe, K., Okhuysen, P. C., Oldfield, E., Olson, D., Orenstein, R., Ortiz, R., Parpart, F., Pastore-Lange, V., Paul, S., Pavlatos, A., Pearce, D. D., Pelz, R., Peterson, S., Pitrak, D., Powers, S. L., Pujet, H. C., Raaum, J. W., Ravishankar, J., Reeder, J., Reilly, N. A., Reyelt, C., Riddell, J., Rimland, D., Robinson, M. L., Rodriguez, A. E., Rodriguez Derouen, V., Rosmarin, C., Rossen, W. L., Rouff, J. R., Sands, M., Savini, C., Schrader, S., Schulte, M. M., Scott, R., Seedhom, H., Sension, M., Sheblehall, A., Shuter, J., Slater, L. N., Slotten, R., Smith, M., Snap, S., States, D. M., Stringer, G., Summers, K. K., Swanson, K., Sweeton, I. B., Szabo, S., Tedaldi, E. M., Telzak, E. E., Thompson, M. A., Thompson, S., Bong, C. T. H., Vaccaro, A., Vasco, L. M., Vecino, I., Verlinghieri, G. K., Visnegarwala, F., Wade, H., Weis, S. E., Weise, J. A., Weissman, S., Wilkin, M., Witter, J. H., Wojtusic, L., Wright, T. J., Yeh, V., Young, B., Zeana, C., Zeh, J., Savio, E., Vacarezza, M., and Pacheco, Antonio Guilherme
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Adult ,CD4-Positive T-Lymphocytes ,Male ,General Science & Technology ,Anti-HIV Agents ,T cell ,lcsh:Medicine ,Antiretroviral Therapy ,HIV Infections ,Biology ,Essential hypertension ,Logistic regression ,Malignancy ,Acquired immunodeficiency syndrome (AIDS) ,Clinical Research ,Antiretroviral Therapy, Highly Active ,microRNA ,medicine ,Genetics ,2.1 Biological and endogenous factors ,Humans ,Highly Active ,Aetiology ,lcsh:Science ,Genetic Association Studies ,Multidisciplinary ,lcsh:R ,Case-control study ,Middle Aged ,medicine.disease ,3. Good health ,Circulating MicroRNA ,MicroRNAs ,medicine.anatomical_structure ,Infectious Diseases ,Good Health and Well Being ,INSIGHT ESPRIT and SMART Study Groups ,Immunology ,HIV-1 ,HIV/AIDS ,lcsh:Q ,Female ,Infection ,Biomarkers ,Biotechnology ,Research Article - Abstract
Introduction The use of anti-retroviral therapy (ART) has dramatically reduced HIV-1 associated morbidity and mortality. However, HIV-1 infected individuals have increased rates of morbidity and mortality compared to the non-HIV-1 infected population and this appears to be related to end-organ diseases collectively referred to as Serious Non-AIDS Events (SNAEs). Circulating miRNAs are reported as promising biomarkers for a number of human disease conditions including those that constitute SNAEs. Our study sought to investigate the potential of selected miRNAs in predicting mortality in HIV-1 infected ART treated individuals. Materials and Methods A set of miRNAs was chosen based on published associations with human disease conditions that constitute SNAEs. This case: control study compared 126 cases (individuals who died whilst on therapy), and 247 matched controls (individuals who remained alive). Cases and controls were ART treated participants of two pivotal HIV-1 trials. The relative abundance of each miRNA in serum was measured, by RTqPCR. Associations with mortality (all-cause, cardiovascular and malignancy) were assessed by logistic regression analysis. Correlations between miRNAs and CD4+ T cell count, hs-CRP, IL-6 and D-dimer were also assessed. Results None of the selected miRNAs was associated with all-cause, cardiovascular or malignancy mortality. The levels of three miRNAs (miRs -21, -122 and -200a) correlated with IL-6 while miR-21 also correlated with D-dimer. Additionally, the abundance of miRs -31, -150 and -223, correlated with baseline CD4+ T cell count while the same three miRNAs plus miR-145 correlated with nadir CD4+ T cell count. Discussion No associations with mortality were found with any circulating miRNA studied. These results cast doubt onto the effectiveness of circulating miRNA as early predictors of mortality or the major underlying diseases that contribute to mortality in participants treated for HIV-1 infection.
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- 2015
12. Development and validation of a risk score for chronic kidney disease in HIV infection using prospective cohort data from the D:A:D study
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Mocroft, Amanda, Lundgren, Jens D., Ross, Michael, Law, Matthew, Reiss, Peter, Kirk, Ole, Smith, Colette, Wentworth, Deborah, Neuhaus, Jacqueline, Fux, Christoph A., Moranne, Olivier, Morlat, Phillipe, Johnson, Margaret A., Ryom, Lene, Lundgren, J. D., Powderly, B., Shortman, N., Moecklinghoff, C., Reilly, G., Franquet, X., Sabin, C. A., Phillips, A., Kirk, O., Reiss, P., Weber, R., Pradier, C., Law, M., d'Arminio Monforte, A., Dabis, F., El-Sadr, W. M., De Wit, S., Ryom, L., Kamara, D., Smith, C., Mocroft, A., Tverland, J., Mansfeld, M., Nielsen, J., Raben, D., Salbøl Brandt, R., Rickenbach, M., Fanti, I., Krum, E., Hillebregt, M., Geffard, S., Sundström, A., Delforge, M., Fontas, E., Torres, F., Mcmanus, H., Wright, S., Kjær, J., Sjøl, A., Meidahl, P., Helweg-Larsen, J., Schmidt Iversen, J., Ross, M., Fux, C. A., Morlat, P., Moranne, O., Kesselring, A. M., Kamara, D. A., Friis-Møller, N., Kowalska, J., Sabin, C., Bruyand, M., Bower, M., Fätkenheuer, G., Donald, A., Grulich, A., Prins, J. M., Kuijpers, T. W., Scherpbier, H. J., van der Meer, J. T. M., Wit, F. W. M. N., Godfried, M. H., van der Poll, T., Nellen, F. J. B., Geerlings, S. E., van Vugt, M., Pajkrt, D., Bos, J. C., Wiersinga, W. J., van der Valk, M., Goorhuis, A., Hovius, J. W., van Eden, J., Henderiks, A., van Hes, A. M. H., Mutschelknauss, M., Nobel, H. E., Pijnappel, F. J. J., Westerman, A. M., Jurriaans, S., Back, N. K. T., Zaaijer, H. L., Berkhout, B., Cornelissen, M. T. E., Schinkel, C. J., Thomas, X. V., van den Berge, M., Stegeman, A., Baas, S., Hage de Looff, L., Versteeg, D., Pronk, M. J. H., Ammerlaan, H. S. M., Korsten-Vorstermans, E. M. H. M., de Munnik, E. S., Jansz, A. R., Tjhie, J., Wegdam, M. C. A., Deiman, B., Scharnhorst, V., van der Plas, A., Weijsenfeld, A. M., van der Ende, M. E., de Vries-Sluijs, T. E. M. S., C. M. van Gorp, E., Schurink, C. A. M., Nouwen, J. 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L., Dimitrakaki, A., Gargalianos-Kakolyris, P., Giannaris, M., Karafoulidou, A., Katsambas, A., Katsarou, O., Kontos, A. N., Kordossis, T., Lazanas, M. K., Panagopoulos, P., Paparizos, V., Papastamopoulos, V., Petrikkos, G., Skoutelis, A., Tsogas, N., Bergin, C. J., Mooka, B., Mamorksy, M. G., Agmon-Levin, N., Karplus, R., Shahar, E., Biglino, A., De Gioanni, M., Montroni, M., Raise, E., Honda, M., Ishisaka, M., Caplinskas, S., Uzdaviniene, V., Schmit, J. C., Mills, G. D., Blackmore, T., Masters, J. A., Morgan, J., Pithie, A., Brunn, J., Ormasssen, V., La Rosa, A., Guerra, O., Espichan, M., Gutierrez, L., Mendo, F., Salazar, R., Knytz, B., Kwiatkowski, J., Castro, R. S., Horta, A., Miranda, A. C., Pinto, I. V., Vera, J., Vinogradova, E., Yakovlev, A., Wood, R., Orrel, C., Arnaiz, J. A., Carrillo, R., Dalmau, D., Jordano, Q., Knobel, H., Larrousse, M., Moreno, J. S., Oretaga, E., Pena, J. N., Spycher, R., Bottone, S., Christen, A., Franc, C., Furrer, H. J., Gayet-Ageron, A., Genné, D., Hochstrasser, S., Moens, C., Nüesch, R., Ruxrungtham, K., Pumpradit, W., Dangthongdee, S., Kiertiburanakul, S., Klinbuayaem, V., Mootsikapun, P., Nonenoy, S., Piyavong, B., Prasithsirikul, W., Raksakulkarn, P., Gazzard, B. G., Ainsworth, J. G., Angus, B. J., Barber, T. J., Brook, M. G., Care, C. D., Chadwick, D. R., Chikohora, M., Churchill, D. R., Cornforth, D., Dockrell, D. H., Easterbrook, P. J., Fox, P. A., Gomez, P. A., Gompels, M. M., Harris, G. M., Herman, S., Jackson, A. G. A., Jebakumar, S. P. R., Kinghorn, G. R., Kuldanek, K. A., Larbalestier, N., Lumsden, M., Maher, T., Mantell, J., Muromba, L., Orkin, C. M., Peters, B. S., Peto, T. E. A., Portsmouth, S. D., Rajamanoharan, S., Ronan, A., Schwenk, A., Slinn, M. A., Stroud, C. J., Thomas, R. C., Wansbrough-Jones, M. H., Whiles, H. J., White, D. J., Williams, E., Williams, I. G., Acosta, E. A., Adamski, A., Antoniskis, D., Aragon, D. R., Barnett, B. J., Baroni, C., Barron, M., Baxter, J. D., Beers, D., Beilke, M., Bemenderfer, D., Bernard, A., Besch, C. L., Bessesen, M. T., Bethel, J. T., Blue, S., Blum, J. D., Boarden, S., Bolan, R. K., Borgman, J. B., Brar, I., Braxton, B. K., Bredeek, U. F., Brennan, R., Britt, D. E., Bulgin-Coleman, D., Bullock, D. E., Campbell, B., Caras, S., Carroll, J., Casey, K. K., Chiang, F., Cindrich, R. B., Clark, C., Cohen, C., Coley, J., Condoluci, D. V., Contreras, R., Corser, J., Cozzolino, J., Daley, L., Dandridge, D., D'Antuono, V., Darcourt Rizo Patron, J. G., Dehovitz, J. A., Dejesus, E., Desjardin, J., Dietrich, C., Dolce, E., Erickson, D., Faber, L. L., Falbo, J., Farrough, M. J., Farthing, C. F., Ferrell-Gonzalez, P., Flynn, H., Frank, M., Freeman, K. F., French, N., Fujita, N., Gahagan, L., Gilson, I., Goetz, M. B., Goodwin, E., Guity, C. K., Gulick, P., Gunderson, E. R., Hale, C. M., Hannah, K., Henderson, H., Hennessey, K., Henry, W. K., Higgins, D. T., Hodder, S. L., Horowitz, H. W., Howe-Pittman, M., Hubbard, J., Hudson, R., Hunter, H., Hutelmyer, C., Insignares, M. T., Jackson, L., Jenny, L., Johnson, D. L., Johnson, G., Johnson, J., Kaatz, J., Kaczmarski, J., Kagan, S., Kantor, C., Kempner, T., Kieckhaus, K., Kimmel, N., Klaus, B. M., Koeppe, J. R., Koirala, J., Kopka, J., Kostman, J. R., Kozal, M. J., Kumar, A., Lampiris, H., Lamprecht, C., Lattanzi, K. M., Lee, J., Leggett, J., Long, C., Loquere, A., Loveless, K., Lucasti, C. J., Macveigh, M., Makohon, L. H., Markowitz, N. P., Marks, C., Martorell, C., Mcfeaters, E., Mcgee, B., Mcintyre, D. M., Mcmanus, E., Melecio, L. G., Melton, D., Mercado, S., Merrifield, E., Mieras, J. A., Mogyoros, M., Moran, F. M., Murphy, K., Mutic, S., Nadeem, I., Nadler, J. P., Ognjan, A., O'Hearn, M., O'Keefe, K., Okhuysen, P. C., Oldfield, E., Olson, D., Orenstein, R., Ortiz, R., Parpart, F., Pastore-Lange, V., Paul, S., Pavlatos, A., Pearce, D. D., Pelz, R., Peterson, S., Pitrak, D., Powers, S. L., Pujet, H. C., Raaum, J. W., Ravishankar, J., Reeder, J., Reilly, N. A., Reyelt, C., Riddell, J., Rimland, D., Robinson, M. L., Rodriguez, A. E., Rodriguez-Barradas, M. C., Rodriguez Derouen, V., Rosmarin, C., Rossen, W. L., Rouff, J. R., Sampson, J. H., Sands, M., Savini, C., Schrader, S., Schulte, M. M., Scott, R., Seedhom, H., Sension, M., Sheble-Hall, A., Shuter, J., Slater, L. N., Slotten, R., Smith, M., Snap, S., States, D. M., Stringer, G., Summers, K. K., Swanson, K., Sweeton, I. B., Szabo, S., Tedaldi, E. M., Telzak, E. E., Thompson, M. A., Thompson, S., Ting Hong Bong, C., Vaccaro, A., Vasco, L. M., Vecino, I., Verlinghieri, G. K., Visnegarwala, F., Wade, B. H., Weis, S. E., Weise, J. A., Weissman, S., Wilkin, A. M., Witter, J. H., Wojtusic, L., Wright, T. J., Yeh, V., Young, B., Zeana, C., Zeh, J., Savio, E., Vacarezza, M., University College of London [London] (UCL), University of Copenhagen = Københavns Universitet (KU), University of New South Wales [Sydney] (UNSW), University of Amsterdam [Amsterdam] (UvA), University of Minnesota [Twin Cities] (UMN), University of Minnesota System, Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Aide à la Décision pour une Médecine Personnalisé - Laboratoire de Biostatistique, Epidémiologie et Recherche Clinique - EA 2415 (AIDMP), Université Montpellier 1 (UM1)-Université de Montpellier (UM), Centre Hospitalier Universitaire de Nice (CHU Nice), Epidémiologie et Biostatistique [Bordeaux], Université Bordeaux Segalen - Bordeaux 2-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Med Microbiol, Infect Dis & Infect Prev, RS: NUTRIM - R3 - Chronic inflammatory disease and wasting, RS: CAPHRI School for Public Health and Primary Care, RS: CAPHRI - R4 - Health Inequities and Societal Participation, Interne Geneeskunde, Chemical Biology, Mocroft, A, Lundgren, J, Ross, M, Law, M, Reiss, P, Kirk, O, Smith, C, Wentworth, D, Neuhaus, J, Fux, C, Moranne, O, Morlat, P, Johnson, M, Ryom, L, Gori, A, Internal medicine, CCA - Innovative therapy, ICaR - Circulation and metabolism, Medical Microbiology and Infection Prevention, CCA - Disease profiling, CCA - Immuno-pathogenesis, Plastic, Reconstructive and Hand Surgery, Mocroft, Amanda, Lundgren, Jens D., Ross, Michael, Law, Matthew, Reiss, Peter, Kirk, Ole, Smith, Colette, Wentworth, Deborah, Neuhaus, Jacqueline, Fux, Christoph A., Moranne, Olivier, Morlat, Phillipe, Johnson, Margaret A., Ryom, Lene, D:a:d Study, Group, Castagna, Antonella, the Royal Free Hospital Clinic, Cohort, and the, Insight, Smart, and ESPRIT, Study, Clinicum, Department of Medicine, Herrada, Anthony, University of Copenhagen = Københavns Universitet (UCPH), AII - Amsterdam institute for Infection and Immunity, APH - Amsterdam Public Health, Global Health, Other departments, Infectious diseases, Paediatric Infectious Diseases / Rheumatology / Immunology, General Internal Medicine, Center of Experimental and Molecular Medicine, Graduate School, Gastroenterology and Hepatology, Dermatology, ACS - Amsterdam Cardiovascular Sciences, Other Research, Anesthesiology, and Bartlett, John
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Male ,Adult ,Age Factors ,Anti-HIV Agents ,CD4 Lymphocyte Count ,Clinical Decision-Making ,Comorbidity ,Female ,HIV ,HIV Infections ,HIV Seropositivity ,Humans ,Incidence ,Kidney ,Middle Aged ,Prospective Studies ,Renal Insufficiency, Chronic ,Risk ,Risk Assessment ,Sex Factors ,urologic and male genital diseases ,Biochemistry ,0302 clinical medicine ,ANTIRETROVIRAL THERAPY ,Adult, Age Factors, Anti-HIV Agents, CD4 Lymphocyte Count, Clinical Decision-Making, Comorbidity, Female, HIV, HIV Infections, HIV Seropositivity, Humans, Incidence, Kidney, Male, Middle Aged, Prospective Studies, Renal Insufficiency, Chronic, Risk, Risk Assessment, Sex Factors ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Age Factor ,Chronic ,STAGE RENAL-DISEASE ,PROTEINURIA ,virus diseases ,11 Medical And Health Sciences ,General Medicine ,ASSOCIATION ,6. Clean water ,female genital diseases and pregnancy complications ,3. Good health ,HIV/AIDS ,Medicine ,Infection ,psychological phenomena and processes ,Human ,medicine.medical_specialty ,Renal function ,NEFROPATIAS ,chronic kidney disease ,risk score model ,12. Responsible consumption ,ESPRIT study group ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Clinical Research ,D:A:D study group ,Intensive care medicine ,medicine (all) ,Molecular Biology ,Royal Free Hospital Clinic Cohort ,Prevention ,Anti-HIV Agent ,medicine.disease ,Prospective Studie ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,Immunology ,Kidney Disease ,PREDICTION ,POSITIVE PERSONS ,030232 urology & nephrology ,Sex Factor ,SDG 3 – Goede gezondheid en welzijn ,Medical and Health Sciences ,GLOMERULAR-FILTRATION-RATE ,[SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology ,INSIGHT study group ,HIV Infection ,LIFE EXPECTANCY ,030212 general & internal medicine ,Renal Insufficiency ,Prospective cohort study ,Framingham Risk Score ,Incidence (epidemiology) ,adult ,age factors ,anti-hiv agents ,CD4 lymphocyte count ,clinical decision-making ,comorbidity ,female ,hiv ,hiv infections ,hiv seropositivity ,humans ,incidence ,kidney ,male ,middle aged ,prospective studies ,renal insufficiency, chronic ,risk ,risk assessment ,sex factors ,SMART study group ,6.1 Pharmaceuticals ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Patient Safety ,Risk assessment ,Biotechnology ,Research Article ,Settore MED/17 - MALATTIE INFETTIVE ,NO ,A:D study group [D] ,General & Internal Medicine ,Diabetes mellitus ,mental disorders ,medicine ,EXPOSURE ,business.industry ,Evaluation of treatments and therapeutic interventions ,Cell Biology ,[SDV.MHEP.UN] Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology ,INDIVIDUALS ,Good Health and Well Being ,[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie ,3121 General medicine, internal medicine and other clinical medicine ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,business ,Kidney disease - Abstract
Background Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment regimen and would identify those at greatest risk of CKD. The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice. Methods and Findings A total of 17,954 HIV-positive individuals from the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study with ≥3 estimated glomerular filtration rate (eGFR) values after 1 January 2004 were included. Baseline was defined as the first eGFR > 60 ml/min/1.73 m2 after 1 January 2004; individuals with exposure to tenofovir, atazanavir, atazanavir/ritonavir, lopinavir/ritonavir, other boosted protease inhibitors before baseline were excluded. CKD was defined as confirmed (>3 mo apart) eGFR ≤ 60 ml/min/1.73 m2. Poisson regression was used to develop a risk score, externally validated on two independent cohorts. In the D:A:D study, 641 individuals developed CKD during 103,185 person-years of follow-up (PYFU; incidence 6.2/1,000 PYFU, 95% CI 5.7–6.7; median follow-up 6.1 y, range 0.3–9.1 y). Older age, intravenous drug use, hepatitis C coinfection, lower baseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular disease (CVD) predicted CKD. The adjusted incidence rate ratios of these nine categorical variables were scaled and summed to create the risk score. The median risk score at baseline was −2 (interquartile range –4 to 2). There was a 1:393 chance of developing CKD in the next 5 y in the low risk group (risk score < 0, 33 events), rising to 1:47 and 1:6 in the medium (risk score 0–4, 103 events) and high risk groups (risk score ≥ 5, 505 events), respectively. Number needed to harm (NNTH) at 5 y when starting unboosted atazanavir or lopinavir/ritonavir among those with a low risk score was 1,702 (95% CI 1,166–3,367); NNTH was 202 (95% CI 159–278) and 21 (95% CI 19–23), respectively, for those with a medium and high risk score. NNTH was 739 (95% CI 506–1462), 88 (95% CI 69–121), and 9 (95% CI 8–10) for those with a low, medium, and high risk score, respectively, starting tenofovir, atazanavir/ritonavir, or another boosted protease inhibitor. The Royal Free Hospital Clinic Cohort included 2,548 individuals, of whom 94 individuals developed CKD (3.7%) during 18,376 PYFU (median follow-up 7.4 y, range 0.3–12.7 y). Of 2,013 individuals included from the SMART/ESPRIT control arms, 32 individuals developed CKD (1.6%) during 8,452 PYFU (median follow-up 4.1 y, range 0.6–8.1 y). External validation showed that the risk score predicted well in these cohorts. Limitations of this study included limited data on race and no information on proteinuria. Conclusions Both traditional and HIV-related risk factors were predictive of CKD. These factors were used to develop a risk score for CKD in HIV infection, externally validated, that has direct clinical relevance for patients and clinicians to weigh the benefits of certain antiretrovirals against the risk of CKD and to identify those at greatest risk of CKD., Editors’ Summary Background About 35 million people are currently infected with HIV, the virus that causes AIDS. HIV destroys CD4 lymphocytes and other immune system cells, leaving infected individuals susceptible to other infections. HIV infection can be controlled, but not cured, using combination antiretroviral therapy (cART), and, nowadays, the life expectancy of many HIV-positive individuals is similar to that of HIV-negative people. HIV-positive individuals nevertheless experience some illnesses more frequently than HIV-negative people do. For example, up to a third of HIV-positive individuals develop chronic kidney disease (CKD), which is associated with an increased risk of cardiovascular disease and death. Persons with CKD may have an impaired effect of the filtration units in the kidneys that remove waste products and excess water from the blood to make urine, thereby leading to a reduced blood filtration rate (the estimated glomerular filtration rate [eGFR]) and waste product accumulation in the blood. Symptoms of CKD, which rarely occur until the disease is advanced, include tiredness, swollen feet, and frequent urination. Advanced stages of CKD cannot be cured, but its progression can be slowed by, for example, controlling hypertension (high blood pressure) and diabetes (two CDK risk factors) and by adopting a healthy lifestyle. Why Was This Study Done? The burden of CKD may increase among HIV-positive individuals as they age, and clinicians need to know which individuals are at high risk of developing CKD when choosing cART regimens for their patients. In addition, clinicians need to be able to identify those HIV-positive individuals at greatest risk of CKD so that they can monitor them for early signs of kidney disease. Some antiretroviral drugs—for example, tenofovir and atazanavir/ritonavir (a boosted protease inhibitor)—are associated with kidney damage. Clinicians may need to weigh the benefits and risks of giving such potentially nephrotoxic drugs to individuals who already have a high CKD risk. Here, the researchers develop and validate a simple, widely applicable risk score (a risk prediction model) for CKD among HIV-positive individuals and investigate the relationship between CKD and potentially nephrotoxic antiretroviral drugs among individuals with different CKD risk score profiles. What Did the Researchers Do and Find? To develop their CKD risk score, the researchers used clinical and demographic data collected from 17,954 HIV-positive individuals enrolled in the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study who had an eGFR > 60 ml/min/1.73 m2 and were not taking a potentially nephrotoxic antiretroviral at baseline. During 103,185 person-years of follow-up, 641 individuals developed CKD. Older age, intravenous drug use, hepatitis C coinfection, lower baseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular disease predicted CKD. The researchers included these nine factors in their risk score model (which is available online) and defined three risk groups: low (risk score < 0), medium (risk score 0–4), and high (risk score ≥ 5) risk of CKD development in the next five years. Specifically, there was a 1 in 393, 1 in 47, and 1 in 6 chance of developing CKD in the next five years in the low, medium, and high risk groups, respectively. Because some patients started to use potentially nephrotoxic antiretroviral drugs during follow-up, the researchers were able to use their risk score model to calculate how many patients would have to be treated with one of these drugs for an additional patient to develop CKD over five years in each risk group. This “number needed to harm” (NNTH) for patients starting treatment with tenofovir, atazanavir/ritonavir, or another boosted protease inhibitor was 739, 88, and 9 in the low, medium, and high risk groups, respectively. Finally, the researchers validated the accuracy of their risk score in two independent HIV study groups. What Do These Findings Mean? These findings provide a simple, validated risk score for CKD and indicate that the NNTH when starting potentially nephrotoxic antiretrovirals was low among HIV-positive individuals at the highest risk of CKD (i.e., treating just nine individuals with nephrotoxic antiretroviral drugs will likely lead to an additional case of CKD in five years). Although various aspects of the study, including the lack of data on race, limit the accuracy of these findings, these findings highlight the need for monitoring, screening, and chronic disease prevention to minimize the risk of HIV-positive individuals developing diabetes, hypertension, or cardiovascular disease, or becoming coinfected with hepatitis C, all of which contribute to the CKD risk score. Moreover, the development of a tool for estimating an individual’s five-year risk of developing CKD with or without the addition of potentially nephrotoxic antiretroviral drugs will enable clinicians and patients to weigh the benefits of certain antiretroviral drugs against the risk of CKD and make informed decisions about treatment options. Additional Information Please access these websites via the online version of this summary at http://dx.doi.org/10.1371/journal.pmed.1001809. Information is available from the US National Institute of Allergy and Infectious Diseases on HIV infection and AIDS NAM/aidsmap provides basic information about HIV/AIDS, summaries of recent research findings on HIV care and treatment, and personal stories about living with AIDS/HIV Information is available from Avert, an international AIDS charity, on many aspects of HIV/AIDS, including personal stories about living with HIV/AIDS The World Health Organization provides information on all aspects of HIV/AIDS (in several languages), including its guidelines on the use of ART for treating and preventing HIV infection The UNAIDS World AIDS Day Report 2014 provides up-to-date information about the AIDS epidemic and efforts to halt it The UK National Health Service Choices website provides information for patients on chronic kidney disease, including some personal stories The US National Kidney Foundation, a not-for-profit organization, provides information about chronic kidney disease (in English and Spanish) A tool for calculating the CDK risk score developed in this study is available Additional information about the D:A:D study is available, Amanda Mocroft and colleagues develop and validate a model for determining risk of developing chronic kidney disease for individuals with HIV if treated with different antiretroviral therapies.
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- 2015
13. Prevalence of hypovitaminosis D and factors associated with vitamin D deficiency and morbidity among HIV-infected patients enrolled in a large Italian cohort
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Vescini F, Cozzi Lepri A, Maggiolo F, De Luca A, Cassola G, Vullo V, Carosi G, Antinori A, Tozzi V, Monforte AD, Icona Foundation Study G.r.o.u.p. Moroni M, Angarano G, Cauda R, Di Perri G, Galli M, Iardino R, Ippolito G, Lazzarin A, Perno CF, Von Schlosser F, Ammassari A, Andreoni M, Balotta C, Bonfanti P, Bonora S, Capobianchi MR, Castagna A, Ceccherini Silberstein F, Gargiulo M, Gervasoni C, Girardi E, Lichtner M, Lo Caputo S, Madeddu G, Marcotullio S, Monno L, Murri R, Mussini C, Puoti M, Torti C, Fanti I, Formenti T, Montroni M, Giacometti A, Costantini A, Riva A, Tirelli U, Martellotta F, Ladisa N, Suter F, Cristini G, Minardi C, Bertelli D, Quirino T, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Mastroianni C, Belvisi V, Molteni C, Chiodera A, Castelli P, Rizzardini G, Ridolfo AL, Foschi A, Salpietro S, Merli S, Carenzi L, Moioli MC, Cicconi P, Esposito R, Gori A, Pastore V, Abrescia N, Chirianni A, De Marco M, Ferrari C, Borghi R, Baldelli F, Belfiori B, Parruti G, Sozio F, Magnani G, Ursitti MA, Emilia R, Arlotti M, Ortolani P, Antonucci G, Narciso P, Zaccarelli M, Gallo L, Acinapura R, De Longis P, Ceccarelli L, Libertone R, Trotta MP, Miccoli A, Cattelan AM, Mura MS, Caramello P, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D., BORDERI, MARCO, RE, MARIA CARLA, VIALE, PIERLUIGI, VERUCCHI, GABRIELLA, PIERGENTILI, BENEDETTA, Vescini F, Cozzi-Lepri A, Borderi M, Re MC, Maggiolo F, De Luca A, Cassola G, Vullo V, Carosi G, Antinori A, Tozzi V, Monforte AD, Icona Foundation Study Group.Moroni M, Angarano G, Cauda R, Di Perri G, Galli M, Iardino R, Ippolito G, Lazzarin A, Perno CF, Viale PL, Von Schlosser F, Ammassari A, Andreoni M, Balotta C, Bonfanti P, Bonora S, Capobianchi MR, Castagna A, Ceccherini-Silberstein F, Gargiulo M, Gervasoni C, Girardi E, Lichtner M, Lo Caputo S, Madeddu G, Marcotullio S, Monno L, Murri R, Mussini C, Puoti M, Torti C, Fanti I, Formenti T, Montroni M, Giacometti A, Costantini A, Riva A, Tirelli U, Martellotta F, Ladisa N, Suter F, Verucchi G, Piergentili B, Cristini G, Minardi C, Bertelli D, Quirino T, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Mastroianni C, Belvisi V, Molteni C, Chiodera A, Castelli P, Rizzardini G, Ridolfo AL, Foschi A, Salpietro S, Merli S, Carenzi L, Moioli MC, Cicconi P, Esposito R, Gori A, Pastore V, Abrescia N, Chirianni A, De Marco M, Ferrari C, Borghi R, Baldelli F, Belfiori B, Parruti G, Sozio F, Magnani G, Ursitti MA, Emilia R, Arlotti M, Ortolani P, Antonucci G, Narciso P, Zaccarelli M, Gallo L, Acinapura R, De Longis P, Ceccarelli L, Libertone R, Trotta MP, Miccoli A, Cattelan AM, Mura MS, Caramello P, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D., Vescini, F, Cozzi Lepri, A, Borderi, M, Re, M, Maggiolo, F, De Luca, A, Cassola, G, Vullo, V, Carosi, G, Antinori, A, Tozzi, V, Monforte, A, Gori, A, Vescini, Fabio, Cozzi lepri, Alessandro, Borderi, Marco, Re, Maria Carla, Maggiolo, Franco, De Luca, Andrea, Cassola, Giovanni, Vullo, Vincenzo, Carosi, Giampiero, Antinori, Andrea, Tozzi, Valerio, Monforte, Antonella D'arminio, Icona Foundation Study, Group, and Castagna, Antonella
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Male ,HIV Infections ,vitamin D ,Logistic regression ,Risk Factors ,Cardiovascular Disease ,Prevalence ,HIV Infection ,Pharmacology (medical) ,Renal Insufficiency ,Chronic ,Vitamin D ,Young adult ,education.field_of_study ,hiv infection ,prognosis ,vitamin d deficiency and insufficiency ,Diabetes Mellitu ,Middle Aged ,Prognosis ,Infectious Diseases ,Anti-Retroviral Agents ,Italy ,Cardiovascular Diseases ,Combination ,Cohort ,Linear Model ,Drug Therapy, Combination ,Female ,Seasons ,prognosi ,Adult ,Africa ,Aged ,Central America ,Diabetes Mellitus ,Drug Therapy ,Humans ,Linear Models ,South America ,Vitamin D Deficiency ,Young Adult ,Human ,medicine.medical_specialty ,Population ,Infectious Disease ,Settore MED/17 - MALATTIE INFETTIVE ,vitamin D deficiency ,Internal medicine ,medicine ,Vitamin D and neurology ,Renal Insufficiency, Chronic ,education ,Survival analysis ,business.industry ,Risk Factor ,Hypovitaminosis D ,HIV ,Odds ratio ,medicine.disease ,vitamin D deficiency and insufficiency ,Immunology ,Anti-Retroviral Agent ,Season ,business - Abstract
Background: A high prevalence of hypovitaminosis D (hypD) in HIV-infected patients has been reported, but reasons are unclear. Methods: The 25 hydroxy vitamin D (vitD) concentration was measured in a sample of HIV-positive patients from Italy enrolled in the Icona Foundation Study. The change in absolute levels of vitD pre/post combination antiretroviral treatment was modelled by linear regression controlling for confounders and seasonality. Factors associated with hypD were identified using logistic regression analysis, and survival analysis was employed to evaluate the prognostic value of vitD concentration to predict severe diseases (diabetes, cardiovascular, renal), AIDS, and death. RESULTS:: We studied 810 patients contributing 1408 vitD measures. Median age was 36 years (range: 20-69). VitD insufficiency (30-75 nmol/L) and deficiency (
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- 2011
14. Favourable evolution of virological and immunological profiles in treated and untreated patients in Italy in the period 1998-2008
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Prosperi, Mc1, Cozzi Lepri, A, Antinori, A, Cassola, G, Torti, C, Ursitti, Ma, Pellizzer, Gp, Giacometti, A, d'Arminio Monforte, A, De Luca, A, Collaborators Moroni M, Icona Foundation Study G. r. o. u. p., Carosi, G, Cauda, R, Di Perri, G, Galli, M, Ghinelli, F, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, Gervasoni, C, Girardi, E, Lo Caputo, S, Maggiolo, F, Murri, R, Mussini, C, Puoti, M, Fanti, I, Formenti, T, Prosperi, Cf, Montroni, M, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Pierri, A, Suter, F, Borderi, M, Verucchi, G, Piergentili, B, Cristini, G, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Falasca, K, Carnevale, G, Lorenzotti, S, Sighinolfi, L, Leoncini, F, Pozzi, M, Pagano, G, Viscoli, G, Alessandrini, A, Piscopo, R, Mazzarello, G, Soscia, F, Tacconi, L, Orani, A, Rossotto, R, Tommasi, D, Congedo, P, Chiodera, A, Castelli, P, Rizzardini, G, Schlacht, I, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Melzi, S, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Fiorino, M, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Baldelli, F, Belfiori, B, Magnani, G, Arlotti, M, Ortolani, P, Andreoni, M, Antonucci, G, Narciso, P, Tozzi, V, Vullo, Vincenzo, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Calbi, M, Gallo, L, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D., Prosperi, M. C. F., Cozzi lepri, A., Antinori, A., Cassola, G., Torti, C., Ursitti, M. A., Pellizzer, G. P., Giacometti, A., D'arminio Monforte, A., De Luca, A, Icona Foundation Study, Group, Castagna, Antonella, Prosperi MC, Cozzi-Lepri A, Antinori A, Cassola G, Torti C, Ursitti MA, Pellizzer GP, Giacometti A, d'Arminio Monforte A, De Luca A, Icona, Moroni M, Carosi G, Cauda R, Di Perri G, Galli M, Ghinelli F, Iardino R, Ippolito G, Lazzarin A, Mazzotta F, Panebianco R, Pastore G, Perno CF, Ammassari A, Arici C, Balotta C, Bonfanti P, Capobianchi MR, Castagna A, Ceccherini-Silberstein F, Gervasoni C, Girardi E, Lo Caputo S, Maggiolo F, Murri R, Mussini C, Puoti M, Fanti I, Formenti T, Prosperi CF, Montroni M, Costantini A, Riva A, Tirelli U, Martellotta F, Ladisa N, Pierri A, Suter F, Borderi M, Verucchi G, Piergentili B, Cristini G, Minardi C, Bertelli D, Quirino T, Abeli C, Manconi PE, Piano P, Vecchiet J, Falasca K, Carnevale G, Lorenzotti S, Sighinolfi L, Leoncini F, Pozzi M, Pagano G, Viscoli G, Alessandrini A, Piscopo R, Mazzarello G, Soscia F, Tacconi L, Orani A, Rossotto R, Tommasi D, Congedo P, Chiodera A, Castelli P, Rizzardini G, Schlacht I, Ridolfo AL, Foschi A, Salpietro S, Merli S, Melzi S, Moioli MC, Cicconi P, Esposito R, Gori A, Fiorino M, Abrescia N, Chirianni A, Izzo CM, De Marco M, Viglietti R, Manzillo E, Ferrari C, Pizzaferri P, Baldelli F, Belfiori B, Magnani G, Arlotti M, Ortolani P, Andreoni M, Antonucci G, Narciso P, Tozzi V, Vullo V, Zaccarelli M, Acinapura R, De Longis P, Trotta MP, Calbi M, Gallo L, Carletti F, Mura MS, Madeddu G, Caramello P, Orofino GC, Sciandra M, Raise E, Ebo F, Pellizzer G, Buonfrate D., Prosperi, M, Cozzi Lepri, A, Antinori, A, Cassola, G, Torti, C, Ursitti, M, Pellizzer, G, Giacometti, A, D'Arminio Monforte, A, and Gori, A
- Subjects
Adult ,Male ,HAART ,Sexual Behavior ,HIV Infections ,Infectious Disease ,HUMAN-IMMUNODEFICIENCY-VIRUS ,Settore MED/17 - MALATTIE INFETTIVE ,Settore MED/07 - MICROBIOLOGIA E MICROBIOLOGIA CLINICA ,Virological response rate ,immunological response rates ,Poisson regression ,Antiretroviral Therapy, Highly Active ,Prevalence ,Humans ,HIV Infection ,Pharmacology (medical) ,Poisson Distribution ,Health Policy ,HIV ,HEPATITIS C VIRUS ,HIV–infected patients ,Viral Load ,CD4 Lymphocyte Count ,Treatment Outcome ,Italy ,HIV-1 ,Female ,Immunological response rate ,Human - Abstract
Background: This study provides an estimate of the proportion of HIV-positive patients in Italian clinics showing an 'adverse prognosis' (defined as a CD4 count â¤200cells/μL or an HIV RNA >50 HIV-1 RNA copies/mL) over time, and investigates whether this proportion varied according to patients' characteristics. Methods: We estimated the annual proportion of patients with a CD4 count â¤200cells/μL or HIV RNA >50copies/mL out of the total number of patients in the Icona Foundation cohort seen in any given year, both overall and after stratifying by demographical and treatment status groups. Generalized estimating equation models for Poisson regression were applied. Results: In 1998-2008, the prevalence of patients with a CD4 count â¤200cells/μL decreased from 14 to 6% [adjusted relative risk (RR) 0.86/year; 95% confidence interval (CI) 0.84-0.88; P50copies/mL decreased from 66 to 40% (adjusted RR 0.95/year; 95% CI 0.95-0.96; P
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- 2011
15. Variable impact on mortality of AIDS-defining events diagnosed during combination antiretroviral therapy : not all AIDS-defining conditions are created equal
- Author
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Antiretroviral Therapy Cohort Collaboration Mocroft A, Sterne JA, Egger M, May M, Grabar S, Furrer H, Sabin C, Fatkenheuer G, Justice A, Reiss P, d'Arminio Monforte A, Gill J, Hogg R, Bonnet F, Kitahata M, Staszewski S, Casabona J, Harris R, Saag M, Chêne G, Costagliola D, Dabis F, D'Arminio Monforte A, de Wolf F, Ledergerber B, Mocroft A, Phillips A, Weller I, Sterne J, Abgrall S, Barin F, Bentata M, Billaud E, Boué F, Burty C, Cabié A, Cotte L, De Truchis P, Duval X, Duvivier C, Enel P, Fredouille Heripret L, Gasnault J, Gaud C, Gilquin J, Katlama C, Khuong MA, Lang JM, Lascaux AS, Launay O, Mahamat A, Mary Krause M, Matheron S, Meynard JL, Pavie J, Pialoux G, Pilorgé F, Poizot Martin I, Pradier C, Reynes J, Rouveix E, Simon A, Tattevin P, Tissot Dupont H, Viard JP, Viget N, Pariente Khayat A, Salomon V, Jacquemet N, Rivet A, Guiguet M, Kousignian I, Lanoy E, Lièvre L, Potard V, Selinger Leneman H, Bouvet E, Crickx B, Ecobichon JL, Leport C, Picard Dahan C, Yeni P, Tisne Dessus D, Weiss L, Salmon D, Sicard D, Auperin I, Roudière L, Fior R, Delfraissy JF, Goujard C, Jung C, Lesprit P, Desplanque N, Meyohas MC, Picard O, Cadranel J, Mayaud C, Bricaire F, Herson S, Clauvel JP, Decazes JM, Gerard L, Molina JM, Diemer M, Sellier P, Berthé H, Dupont C, Chandemerle C, Mortier E, Honoré P, Jeantils V, Tassi S, Mechali D, Taverne B, Gourdon F, Laurichesse H, Fresard A, Lucht F, Eglinger P, Faller JP, Bazin C, Verdon R, Boibieux A, Peyramond D, Livrozet JM, Touraine JL, Trepo C, Ravaux I, Delmont JP, Moreau J, Gastaut JA, Retornaz F, Soubeyrand J, Allegre T, Blanc PA, Galinier A, Ruiz JM, Lepeu G, Granet Brunello P, Esterni JP, Pelissier L, Cohen Valensi R, Nezri M, Chadapaud S, Laffeuillade A, May T, Rabaud C, Raffi F, Arvieux C, Michelet C, Borsa Lebas F, Caron F, Fraisse P, Rey D, Arlet Suau E, Cuzin L, Massip P, Thiercelin Legrand MF, Yasdanpanah Y, Pradinaud R, Sobesky M, Contant M, Montroni M, Scalise G, Braschi MC, Riva A, Tirelli U, Martellotta F, Pastore G, Ladisa N, Suter F, Arici C, Chiodo F, Colangeli V, Fiorini C, Carosi G, Cristini G, Torti C, Minardi C, Bertelli D, Quirino T, Manconi PE, Piano P, Cosco L, Scerbo A, Vecchiet J, D'Alessandro M, Santoro D, Pusterla L, Carnevale G, Lorenzotti S, Viganò P, Mena M, Ghinelli F, Sighinolfi L, Leoncini F, Mazzotta F, Pozzi M, Lo Caputo S, Grisorio B, Ferrara S, Grima P, Grima PF, Pagano G, Cassola G, Alessandrini A, Piscopo R, Toti M, Trezzi M, Soscia F, Tacconi L, Orani A, Perini P, Scasso A, Vincenti A, Chiodera F, Castelli P, Scalzini A, Palvarini L, Moroni M, Lazzarin A, Rizzardini G, Caggese L, Cicconi P, Galli A, Merli S, Pastecchia C, Moioli MC, Esposito R, Mussini C, Abrescia N, Chirianni A, Izzo CM, Piazza M, De Marco M, Viglietti R, Manzillo E, Colomba A, Abbadessa V, Prestileo T, Mancuso S, Ferrari C, Pizzaferri P, Filice G, Minoli L, Bruno R, Novati S, Baldelli F, Camanni G, Petrelli E, Cioppi A, Alberici F, Ruggieri A, Menichetti F, Martinelli C, De Stefano C, La Gala A, Ballardini G, Rizzo E, Magnani G, Ursitti MA, Arlotti M, Ortolani P, Cauda R, Dianzani F, Ippolito G, Antinori A, Antonucci G, Ciardi M, Narciso P, Petrosillo N, Vullo V, De Luca A, Zaccarelli M, Acinapura R, De Longis P, Trotta MP, Noto P, Lichtner M, Capobianchi MR, Carletti F, Girardi E, Pezzotti P, Rezza G, Mura MS, Mannazzu M, Caramello P, Di Perri G, Orofino GC, Sciandra M, Grossi PA, Basilico C, Poggio A, Bottari G, Raise E, Ebo F, Pellizzer G, Buonfrate D, Resta F, Loso K, Cozzi Lepri A, Battegay M, Bernasconi E, Böni J, Bucher H, Bürgisser P, Cattacin S, Cavassini M, Dubs R, Elzi L, Erb P, Fischer M, Flepp M, Fontana A, Francioli P, Gorgievski M, Günthard H, Hirsch H, Hirschel B, Hösli I, Kahlert C, Kaiser L, Karrer U, Kind C, Klimkait T, Martinetti G, Martinez B, Müller N, Nadal D, Opravil M, Paccaud F, Pantaleo G, Rickenbach M, Rudin C, Schmid P, Schultze D, Schüpbach J, Speck R, Taffé P, Tarr P, Telenti A, Trkola A, Vernazza P, Weber R, Yerly S, Gras LA, van Sighem AI, Smit C, Bronsveld W, Hillebrand Haverkort ME, Prins JM, Branger J, Eeftinck Schattenkerk JK, Gisolf J, Godfried MH, Lange JM, Lettinga KD, van der Meer JT, Nellen FJ, van der Poll T, Ruys TA, Steingrover R, Vermeulen JN, Vrouenraets SM, van Vugt M, Wit FW, Kuijpers TW, Pajkrt D, Scherpbier HJ, van Eeden A, Brinkman K, van den Berk GE, Blok WL, Frissen PH, Roos JC, Schouten WE, Mulder JW, van Gorp EC, Wagenaar J, Veenstra J, Danner SA, Van Agtmael MA, Claessen FA, Perenboom RM, Rijkeboer A, van Vonderen MG, Richter C, van der Berg J, Vriesendorp R, Jeurissen FJ, Kauffmann RH, Pogány K, Bravenboer B, ten Napel CH, Kootstra GJ, Sprenger HG, van Assen S, van Leeuwen JT, Doedens R, Scholvinck EH, ten Kate RW, Soetekouw R, van Houte D, Polée MB, Kroon FP, van den Broek PJ, van Dissel JT, Schippers EF, Schreij G, van der Geest S, Lowe S, Verbon A, Koopmans PP, Van Crevel R, de Groot R, Keuter M, Post F, van der Ven AJ, Warris A, van der Ende ME, Gyssens IC, van der Feltz M, Nouwen JL, Rijnders BJ, de Vries TE, Driessen G, van der Flier M, Hartwig NG, Juttman JR, van Kasteren ME, Van de Heul C, Hoepelman IM, Schneider MM, Bonten MJ, Borleffs JC, Ellerbroek PM, Jaspers CA, Mudrikove T, Schurink CA, Gisolf EH, Geelen SP, Wolfs TF, Faber T, Tanis AA, Groeneveld PH, den Hollander JG, Duits AJ, Winkel K, Back NK, Bakker ME, Berkhout B, Jurriaans S, Zaaijer HL, Cuijpers T, Rietra PJ, Roozendaal KJ, Pauw W, van Zanten AP, Smits PH, von Blomberg BM, Savelkoul P, Pettersson A, Swanink CM, Franck PF, Lampe AS, Jansen CL, Hendriks R, Benne CA, Veenendaal D, Storm H, Weel J, van Zeijl JH, Kroes AC, Claas HC, Bruggeman CA, Goossens VJ, Galama JM, Melchers WJ, Poort YA, Doornum GJ, Niesters MG, Osterhaus AD, Schutten M, Buiting AG, Swaans CA, Boucher CA, Schuurman R, Boel E, Jansz AF, Veldkamp A, Beijnen JH, Huitema AD, Burger DM, Hugen PW, van Kan HJ, Losso M, Duran A, Vetter N, Karpov I, Vassilenko A, Mitsura VM, Suetnov O, Clumeck N, De Wit S, Poll B, Colebunders R, Kostov K, Begovac J, Machala L, Rozsypal H, Sedlacek D, Nielsen J, Lundgren J, Benfield T, Kirk O, Gerstoft J, Katzenstein T, Hansen AB, Skinhøj P, Pedersen C, Oestergaard L, Zilmer K, Ristola M, Girard PM, Vanhems P, Rockstroh J, Schmidt R, van Lunzen J, Degen O, Stellbrink HJ, Bogner J, Kosmidis J, Gargalianos P, Xylomenos G, Perdios J, Panos G, Filandras A, Karabatsaki E, Sambattakou H, Banhegyi D, Mulcahy F, Yust I, Turner D, Burke M, Pollack S, Hassoun G, Maayan S, Chiesi A, Mazeu I, Pristera R, Gabbuti A, Montesarchio E, Gargiulo M, Iacomi F, Vlassi C, Finazzi R, Galli M, Ridolfo A, Rozentale B, Aldins P, Chaplinskas S, Hemmer R, Staub T, Bruun J, Maeland A, Ormaasen V, Knysz B, Gasiorowski J, Horban A, Prokopowicz D, Wiercinska Drapalo A, Boron Kaczmarska A, Pynka M, Beniowski M, Mularska E, Trocha H, Antunes F, Valadas E, Mansinho K, Maltez F, Duiculescu D, Rakhmanova A, Vinogradova E, Buzunova S, Jevtovic D, Mokrás M, Staneková D, González Lahoz J, Soriano V, Martin Carbonero L, Labarga P, Clotet B, Jou A, Conejero J, Tural C, Gatell JM, Miró JM, Domingo P, Gutierrez M, Mateo G, Sambeat MA, Karlsson A, Persson PO, Flamholc L, Boffi E, Kravchenko E, Chentsova N, Barton S, Johnson AM, Mercey D, Johnson MA, Murphy M, Weber J, Scullard G, Fisher M, Brettle R, Gatell J, Gazzard B, Friis Møller N, Bannister W, Ellefson M, Borch A, Podlekareva D, Holkmann Olsen C, Kjaer J, Peters L, Reekie J, Raffanti S, Dieterch D, Becker S, Scarsella A, Fusco G, Most B, Balu R, Rana R, Beckerman R, Ising T, Fusco J, Irek R, Johnson B, Hirani A, DeJesus E, Pierone G, Lackey P, Irek C, Johnson A, Burdick J, Leon S, Arch J, Helm EB, Carlebach A, Müller A, Haberl A, Nisius G, Lennemann T, Stephan C, Bickel M, Mösch M, Gute P, Locher L, Lutz T, Klauke S, Knecht G, Khaykin P, Doerr HW, Stürmer M, Babacan E, von Hentig N, Beylot J, Dupon M, Longy Boursier M, Pellegrin JL, Ragnaud JM, Salamon R, Thiébaut R, Lewden C, Lawson Ayayi S, Mercié P, Moreau JF, Morlat P, Bernard N, Lacoste D, Malvy D, Neau D, Blaizeau MJ, Decoin M, Delveaux S, Hannapier C, Labarrère S, Lavignolle Aurillac V, Uwamaliya Nziyumvira B, Palmer G, Touchard D, Balestre E, Alioum A, Jacqmin Gadda H, Bonarek M, Coadou B, Gellie P, Nouts C, Bocquentin F, Dutronc H, Lafarie S, Aslan A, Pistonne T, Thibaut P, Vatan R, Chambon D, De La Taille C, Cazorla C, Ocho A, Viallard JF, Caubet O, Cipriano C, Lazaro E, Couzigou P, Castera L, Fleury H, Lafon ME, Masquelier B, Pellegrin I, Breilh D, Blanco P, Loste P, Caunègre L, Bonnal F, Farbos S, Ferrand M, Ceccaldi J, Tchamgoué S, De Witte S, Buy E, Alexander C, Barrios R, Braitstein P, Brumme Z, Chan K, Cote H, Gataric N, Geller J, Guillemi S, Harrigan PR, Harris M, Joy R, Levy A, Montaner J, Montessori V, Palepu A, Phillips E, Phillips P, Press N, Tyndall M, Wood E, Yip B, Bhagani S, Breen R, Byrne P, Carroll A, Cuthbertson Z, Dunleavy A, Geretti AM, Heelan B, Johnson M, Kinloch de Loes S, Lipman M, Madge S, Marshall N, Nair D, Nebbia G, Prinz B, Shah S, Swader L, Tyrer M, Youle M, Chaloner C, Grabowska H, Holloway J, Puradiredja J, Ransom D, Tsintas R, Bansi L, Fox Z, Harris E, Hill T, Lampe F, Lodwick R, Smith C, Amoah E, Booth C, Clewley G, Garcia Diaz A, Gregory B, Janossy G, Labbett W, Thomas M, Read R, Krentz H, Beckthold B, Schmeisser N, Alquézar A, Esteve A, Podzamczer D, Murillas J, Romero A, Agustí C, Agüero F, Ferrer E, Riera M, Segura F, Navarro G, Force L, Vilaró J, Masabeu A, García I, Guadarrama M, Montoliu A, Ortega N, Lazzari E, Puchol E, Sanchez M, Blanco JL, Garcia Alcaide F, Martinez E, Mallolas J, López Dieguez M, García Goez JF, Sirera G, Romeu J, Negredo E, Miranda C, Capitan MC, Olmo M, Barragan P, Saumoy M, Bolao F, Cabellos C, Peña C, Sala M, Cervantes M, Jose Amengual M, Navarro M, Penelo E, Barrufet P, Raper JL, Mugavero MJ, Willig JH, Schumacher J, Chang PW, Westfall AO, Cloud G, Lin HY, Acosta EP, Colette Kempf M, Allison JJ, Pisu M., NAPPA, SALVATORE, Mocroft, A, Mancuso, S, Antiretroviral Therapy Cohort Collaboration Mocroft, A, Sterne, Ja, Egger, M, May, M, Grabar, S, Furrer, H, Sabin, C, Fatkenheuer, G, Justice, A, Reiss, P, d'Arminio Monforte, A, Gill, J, Hogg, R, Bonnet, F, Kitahata, M, Staszewski, S, Casabona, J, Harris, R, Saag, M, Chêne, G, Costagliola, D, Dabis, F, D'Arminio Monforte, A, de Wolf, F, Ledergerber, B, Phillips, A, Weller, I, Sterne, J, Abgrall, S, Barin, F, Bentata, M, Billaud, E, Boué, F, Burty, C, Cabié, A, Cotte, L, De Truchis, P, Duval, X, Duvivier, C, Enel, P, Fredouille Heripret, L, Gasnault, J, Gaud, C, Gilquin, J, Katlama, C, Khuong, Ma, Lang, Jm, Lascaux, A, Launay, O, Mahamat, A, Mary Krause, M, Matheron, S, Meynard, Jl, Pavie, J, Pialoux, G, Pilorgé, F, Poizot Martin, I, Pradier, C, Reynes, J, Rouveix, E, Simon, A, Tattevin, P, Tissot Dupont, H, Viard, Jp, Viget, N, Pariente Khayat, A, Salomon, V, Jacquemet, N, Rivet, A, Guiguet, M, Kousignian, I, Lanoy, E, Lièvre, L, Potard, V, Selinger Leneman, H, Bouvet, E, Crickx, B, Ecobichon, Jl, Leport, C, Picard Dahan, C, Yeni, P, Tisne Dessus, D, Weiss, L, Salmon, D, Sicard, D, Auperin, I, Roudière, L, Fior, R, Delfraissy, Jf, Goujard, C, Jung, C, Lesprit, P, Desplanque, N, Meyohas, Mc, Picard, O, Cadranel, J, Mayaud, C, Bricaire, F, Herson, S, Clauvel, Jp, Decazes, Jm, Gerard, L, Molina, Jm, Diemer, M, Sellier, P, Berthé, H, Dupont, C, Chandemerle, C, Mortier, E, Honoré, P, Jeantils, V, Tassi, S, Mechali, D, Taverne, B, Gourdon, F, Laurichesse, H, Fresard, A, Lucht, F, Eglinger, P, Faller, Jp, Bazin, C, Verdon, R, Boibieux, A, Peyramond, D, Livrozet, Jm, Touraine, Jl, Trepo, C, Ravaux, I, Delmont, Jp, Moreau, J, Gastaut, Ja, Retornaz, F, Soubeyrand, J, Allegre, T, Blanc, Pa, Galinier, A, Ruiz, Jm, Lepeu, G, Granet Brunello, P, Esterni, Jp, Pelissier, L, Cohen Valensi, R, Nezri, M, Chadapaud, S, Laffeuillade, A, May, T, Rabaud, C, Raffi, F, Arvieux, C, Michelet, C, Borsa Lebas, F, Caron, F, Fraisse, P, Rey, D, Arlet Suau, E, Cuzin, L, Massip, P, Thiercelin Legrand, Mf, Yasdanpanah, Y, Pradinaud, R, Sobesky, M, Contant, M, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Martellotta, F, Pastore, G, Ladisa, N, Suter, F, Arici, C, Chiodo, F, Colangeli, V, Fiorini, C, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Cosco, L, Scerbo, A, Vecchiet, J, D'Alessandro, M, Santoro, D, Pusterla, L, Carnevale, G, Lorenzotti, S, Viganò, P, Mena, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Lo Caputo, S, Grisorio, B, Ferrara, S, Grima, P, Grima, Pf, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Toti, M, Trezzi, M, Soscia, F, Tacconi, L, Orani, A, Perini, P, Scasso, A, Vincenti, A, Chiodera, F, Castelli, P, Scalzini, A, Palvarini, L, Moroni, M, Lazzarin, A, Rizzardini, G, Caggese, L, Cicconi, P, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Mussini, C, Abrescia, N, Chirianni, A, Izzo, Cm, Piazza, M, De Marco, M, Viglietti, R, Manzillo, E, Nappa, Salvatore, Colomba, A, Abbadessa, V, Prestileo, T, Ferrari, C, Pizzaferri, P, Filice, G, Minoli, L, Bruno, R, Novati, S, Baldelli, F, Camanni, G, Petrelli, E, Cioppi, A, Alberici, F, Ruggieri, A, Menichetti, F, Martinelli, C, De Stefano, C, La Gala, A, Ballardini, G, Rizzo, E, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Dianzani, F, Ippolito, G, Antinori, A, Antonucci, G, Ciardi, M, Narciso, P, Petrosillo, N, Vullo, V, De Luca, A, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Noto, P, Lichtner, M, Capobianchi, Mr, Carletti, F, Girardi, E, Pezzotti, P, Rezza, G, Mura, M, Mannazzu, M, Caramello, P, Di Perri, G, Orofino, Gc, Sciandra, M, Grossi, Pa, Basilico, C, Poggio, A, Bottari, G, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Resta, F, Loso, K, Cozzi Lepri, A, Battegay, M, Bernasconi, E, Böni, J, Bucher, H, Bürgisser, P, Cattacin, S, Cavassini, M, Dubs, R, Elzi, L, Erb, P, Fischer, M, Flepp, M, Fontana, A, Francioli, P, Gorgievski, M, Günthard, H, Hirsch, H, Hirschel, B, Hösli, I, Kahlert, C, Kaiser, L, 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Male ,Infectious diseases and international health [NCEBP 13] ,Lymphoma ,030312 virology ,Esophageal candidiasis ,Cohort Studies ,0302 clinical medicine ,Interquartile range ,030212 general & internal medicine ,AIDS-Related ,Lymphoma, AIDS-Related ,0303 health sciences ,Mortality rate ,Progressive multifocal leukoencephalopathy ,Hazard ratio ,Prognosis ,3. Good health ,Pathogenesis and modulation of inflammation [N4i 1] ,Infectious Diseases ,Combination ,Drug Therapy, Combination ,Female ,Infection and autoimmunity [NCMLS 1] ,Human ,Microbiology (medical) ,Adult ,medicine.medical_specialty ,Prognosi ,Anti-HIV Agents ,antiretroviral therapy ,Infectious Disease ,Article ,AIDS-Related Opportunistic Infection ,03 medical and health sciences ,Acquired immunodeficiency syndrome (AIDS) ,Drug Therapy ,Internal medicine ,medicine ,Humans ,AIDS-defining event ,Proportional Hazards Models ,AIDS-Related Opportunistic Infections/diagnosis/ mortality ,Acquired Immunodeficiency Syndrome/complications/diagnosis/drug ,therapy/ mortality ,Anti-HIV Agents/ therapeutic use ,AIDS-Related/diagnosis/mortality ,Acquired Immunodeficiency Syndrome ,AIDS-Related Opportunistic Infections ,business.industry ,Proportional hazards model ,Poverty-related infectious diseases [N4i 3] ,Anti-HIV Agent ,medicine.disease ,mortality ,Confidence interval ,Immunology ,Proportional Hazards Model ,Cohort Studie ,business - Abstract
Contains fulltext : 80963.pdf (Publisher’s version ) (Open Access) BACKGROUND: The extent to which mortality differs following individual acquired immunodeficiency syndrome (AIDS)-defining events (ADEs) has not been assessed among patients initiating combination antiretroviral therapy. METHODS: We analyzed data from 31,620 patients with no prior ADEs who started combination antiretroviral therapy. Cox proportional hazards models were used to estimate mortality hazard ratios for each ADE that occurred in >50 patients, after stratification by cohort and adjustment for sex, HIV transmission group, number of antiretroviral drugs initiated, regimen, age, date of starting combination antiretroviral therapy, and CD4+ cell count and HIV RNA load at initiation of combination antiretroviral therapy. ADEs that occurred in
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- 2009
16. Development and Validation of a Risk Score for Chronic Kidney Disease in HIV Infection Using Prospective Cohort Data from the D:A:D Study
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C., Dever, R. L., Donohue, W. A., Doong, N. C., Dwyer, D. E., Dyer, J., Eu, B., Ferguson, V. W., French, M. A. H., Garsia, R. J., Hudson, J. H., Jeganathan, S., Konecny, P., Mccormack, C. L., Mcmurchie, M., Moore, R. J., Moussa, M. B., Piper, M., Read, T., Roney, J. J., Shaw, D. R., Silvers, J., Smith, D. J., Street, A. C., Vale, R. J., Wendt, N. A., Wood, H., Youds, D. W., Zillman, J., Tozeau, V., de Roo, A., Leonard, P., Lynen, L., Moutschen, M., Pereira, L. C., Souza, T. N. L., Schechter, M., Zajdenverg, R., Almeida, M. M. T. B., Araujo, F., Bahia, F., Brites, C., Caseiro, M. M., Casseb, J., Etzel, A., Falco, G. G., Filho, E. C. J., Flint, S. R., Gonzales, C. R., Madruga, J. V. R., Passos, L. N., Reuter, T., Sidi, L. C., Toscano, A. L. C., Cherban, E., Conway, B., Dufour, C., Foster, A., Haase, D., Haldane, H., Klein, M., Lessard, B., Martel, A., Martel, C., Paradis, E., Schlech, W., Schmidt, S., Thompson, B., Vezina, S., Wolff Reyes, M. J., Northland, R., Hergens, L., Loftheim, I. R., Raukas, M., Justinen, J., Landman, R., Abel, S., Abgrall, S., Amat, K., Auperin, L., Barruet, R., Benalycherif, A., Benammar, N., Bentata, M., Besnier, J. M., Blanc, M., Cabie, A., Chavannet, P., Dargere, S., de la Tribonniere, X., Debord, T., Decaux, N., Delgado, J., Frixon-Marin, V., Genet, C., Gerard, L., Gilquin, J., Jeantils, V., Kouadio, H., Leclercq, P., Lelievre, J. -D., Michon, C. P., Nau, P., Pacanowski, J., Piketty, C., Salmon, D., Schmit, J. L., Serini, M. A., Tassi, S., Touam, F., Verdon, R., Weinbreck, P., Yazdanpanah, Y., Yeni, P., Bitsch, S., Bogner, J. R., Goebel, F. D., Lehmann, C., Lennemann, T., Potthof, A., Wasmuth, J. C., Wiedemeyer, K., Hatzakis, A., Touloumi, G., Antoniadou, A., Daikos, G. L., Dimitrakaki, A., Gargalianos-Kakolyris, P., Giannaris, M., Karafoulidou, A., Katsambas, A., Katsarou, O., Kontos, A. N., Kordossis, T., Lazanas, M. K., Panagopoulos, P., Paparizos, V., Papastamopoulos, V., Petrikkos, G., Skoutelis, A., Tsogas, N., Bergin, C. J., Mooka, B., Mamorksy, M. G., Agmon-Levin, N., Karplus, R., Shahar, E., Biglino, A., De Gioanni, M., Montroni, M., Raise, E., Honda, M., Ishisaka, M., Caplinskas, S., Uzdaviniene, V., Schmit, J. C., Mills, G. D., Blackmore, T., Masters, J. A., Morgan, J., Pithie, A., Brunn, J., Ormasssen, V., La Rosa, A., Guerra, O., Espichan, M., Gutierrez, L., Mendo, F., Salazar, R., Knytz, B., Kwiatkowski, J., Castro, R. S., Horta, A., Miranda, A. C., Pinto, I. V., Vera, J., Vinogradova, E., Yakovlev, A., Wood, R., Orrel, C., Arnaiz, J. A., Carrillo, R., Dalmau, D., Jordano, Q., Knobel, H., Larrousse, M., Moreno, J. S., Oretaga, E., Pena, J. N., Spycher, R., Bottone, S., Christen, A., Franc, C., Furrer, H. J., Gayet-Ageron, A., Genne, D., Hochstrasser, S., Moens, C., Nuesch, R., Ruxrungtham, K., Pumpradit, W., Dangthongdee, S., Kiertiburanakul, S., Klinbuayaem, V., Mootsikapun, P., Nonenoy, S., Piyavong, B., Prasithsirikul, W., Raksakulkarn, P., Gazzard, B. G., Ainsworth, J. G., Angus, B. J., Barber, T. J., Brook, M. G., Care, C. D., Chadwick, D. R., Chikohora, M., Churchill, D. R., Cornforth, D., Dockrell, D. H., Easterbrook, P. J., Fox, P. A., Gomez, P. A., Gompels, M. M., Harris, G. M., Herman, S., Jackson, A. G. A., Jebakumar, S. P. R., Kinghorn, G. R., Kuldanek, K. A., Larbalestier, N., Lumsden, M., Maher, T., Mantell, J., Muromba, L., Orkin, C. M., Palfreeman, A. J., Peters, B. S., Peto, T. E. A., Portsmouth, S. D., Rajamanoharan, S., Ronan, A., Schwenk, A., Slinn, M. A., Stroud, C. J., Thomas, R. C., Wansbrough-Jones, M. H., Whiles, H. J., White, D. J., Williams, E., Williams, I. G., Acosta, E. A., Adamski, A., Antoniskis, D., Aragon, D. R., Barnett, B. J., Baroni, C., Barron, M., Baxter, J. D., Beers, D., Beilke, M., Bemenderfer, D., Bernard, A., Besch, C. L., Bessesen, M. T., Bethel, J. T., Blue, S., Blum, J. D., Boarden, S., Bolan, R. K., Borgman, J. B., Brar, I., Braxton, B. K., Bredeek, U. F., Brennan, R., Britt, D. E., Bulgin-Coleman, D., Bullock, D. E., Campbell, B., Caras, S., Carroll, J., Casey, K. K., Chiang, F., Cindrich, R. B., Clark, C., Cohen, C., Coley, J., Condoluci, D. V., Contreras, R., Corser, J., Cozzolino, J., Daley, L., Dandridge, D., D'Antuono, V., Darcourt Rizo Patron, J. G., Dehovitz, J. A., Dejesus, E., Desjardin, J., Dietrich, C., Dolce, E., Erickson, D., Faber, L. L., Falbo, J., Farrough, M. J., Farthing, C. F., Ferrell-Gonzalez, P., Flynn, H., Frank, M., Freeman, K. F., French, N., Fujita, N., Gahagan, L., Gilson, I., Goetz, M. B., Goodwin, E., Guity, C. K., Gulick, P., Gunderson, E. R., Hale, C. M., Hannah, K., Henderson, H., Hennessey, K., Henry, W. K., Higgins, D. T., Hodder, S. L., Horowitz, H. W., Howe-Pittman, M., Hubbard, J., Hudson, R., Hunter, H., Hutelmyer, C., Insignares, M. T., Jackson, L., Jenny, L., Johnson, D. L., Johnson, G., Johnson, J., Kaatz, J., Kaczmarski, J., Kagan, S., Kantor, C., Kempner, T., Kieckhaus, K., Kimmel, N., Klaus, B. M., Koeppe, J. R., Koirala, J., Kopka, J., Kostman, J. R., Kozal, M. J., Kumar, A., Lampiris, H., Lamprecht, C., Lattanzi, K. M., Lee, J., Leggett, J., Long, C., Loquere, A., Loveless, K., Lucasti, C. J., Macveigh, M., Makohon, L. H., Markowitz, N. P., Marks, C., Martorell, C., Mcfeaters, E., Mcgee, B., Mcintyre, D. M., Mcmanus, E., Melecio, L. G., Melton, D., Mercado, S., Merrifield, E., Mieras, J. A., Mogyoros, M., Moran, F. M., Murphy, K., Mutic, S., Nadeem, I., Nadler, J. P., Ognjan, A., O'Hearn, M., O'Keefe, K., Okhuysen, P. C., Oldfield, E., Olson, D., Orenstein, R., Ortiz, R., Parpart, F., Pastore-Lange, V., Paul, S., Pavlatos, A., Pearce, D. D., Pelz, R., Peterson, S., Pitrak, D., Powers, S. L., Pujet, H. C., Raaum, J. W., Ravishankar, J., Reeder, J., Reilly, N. A., Reyelt, C., Riddell, J., Rimland, D., Robinson, M. L., Rodriguez, A. E., Rodriguez-Barradas, M. C., Rodriguez Derouen, V., Rosmarin, C., Rossen, W. L., Rouff, J. R., Sampson, J. H., Sands, M., Savini, C., Schrader, S., Schulte, M. M., Scott, R., Seedhom, H., Sension, M., Sheble-Hall, A., Shuter, J., Slater, L. N., Slotten, R., Smith, M., Snap, S., States, D. M., Stringer, G., Summers, K. K., Swanson, K., Sweeton, I. B., Szabo, S., Telzak, E. E., Thompson, M. A., Thompson, S., Ting Hong Bong, C., Vaccaro, A., Vasco, L. M., Vecino, I., Verlinghieri, G. K., Visnegarwala, F., Wade, B. H., Weis, S. E., Weise, J. A., Weissman, S., Wilkin, A. M., Witter, J. H., Wojtusic, L., Wright, T. J., Yeh, V., Young, B., Zeana, C., Zeh, J., Savio, E., Vacarezza, M., and Cauda R. (ORCID:0000-0002-1498-4229)
- Abstract
Chronic kidney disease (CKD) is a major health issue for HIV-positive individuals, associated with increased morbidity and mortality. Development and implementation of a risk score model for CKD would allow comparison of the risks and benefits of adding potentially nephrotoxic antiretrovirals to a treatment regimen and would identify those at greatest risk of CKD. The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice. A total of 17,954 HIV-positive individuals from the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study with ≥3 estimated glomerular filtration rate (eGFR) values after 1 January 2004 were included. Baseline was defined as the first eGFR > 60 ml/min/1.73 m2 after 1 January 2004; individuals with exposure to tenofovir, atazanavir, atazanavir/ritonavir, lopinavir/ritonavir, other boosted protease inhibitors before baseline were excluded. CKD was defined as confirmed (>3 mo apart) eGFR ≤ 60 ml/min/1.73 m2. Poisson regression was used to develop a risk score, externally validated on two independent cohorts. In the D:A:D study, 641 individuals developed CKD during 103,185 person-years of follow-up (PYFU; incidence 6.2/1,000 PYFU, 95% CI 5.7–6.7; median follow-up 6.1 y, range 0.3–9.1 y). Older age, intravenous drug use, hepatitis C coinfection, lower baseline eGFR, female gender, lower CD4 count nadir, hypertension, diabetes, and cardiovascular disease (CVD) predicted CKD. The adjusted incidence rate ratios of these nine categorical variables were scaled and summed to create the risk score. The median risk score at baseline was −2 (interquartile range –4 to 2). There was a 1:393 chance of developing CKD in the next 5 y in the low risk group (risk score < 0, 33 events), rising to 1:47 and 1:6 in the medium (risk score 0–4, 103 events) and high risk groups (risk score ≥ 5, 505 events)
- Published
- 2015
17. Clinical and immunological assessment in HIV+ subjects receiving inosine-pranobex. A randomised, multicentric study
- Author
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De Simone, C., Albertini, F., Almaviva, M., Angarano, G., Chiodo, F., Costigliola, P., Delia, S., Ferlini, A., Gritti, F., Mazzarello, G., Milazzo, F., Montroni, M., Narciso, P., Pastore, G., Raise, E., Santini, G., Sorice, F., Terragna, A., Visco, G., and Vullo, V.
- Published
- 1989
- Full Text
- View/download PDF
18. Role of serum free light chains in predicting HIV-associated non-Hodgkin lymphoma and Hodgkin's lymphoma and its correlation with antiretroviral therapy
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Bibas, M, Trotta, Mp, Cozzi Lepri, A, Lorenzini, P, Pinnetti, C, Rizzardini, G, Angarano, G, Caramello, P, Sighinolfi, L, Mastroianni, Cm, Mazzarello, G, Di Caro, A, Di Giacomo, C, d'Arminio Monforte, A, Antinori, A, Collaborators: Moroni M, ICONA Foundation Study G. r. o. u. p., Carosi, G, Cauda, R, Chiodo, F, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Montroni, M, Costantini, A, Frontini, F, Giacometti, A, Riva, A, Carrisa, C, Maggiolo, F, Lazzari, G, Viale, P, Verucchi, G, Vanini, E, Torti, C, Minardi, C, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Falasca, K, Sighinolfi, L, Segala, D, Mazzotta, F, Cassola, G, Piscopo, R, Viscoli, C, Alessandrini, A, Mastroianni, C, Belvisi, V, Caremma, I, Chiodera, A, Castelli, P, Ridolfo, A, Piolini, R, Zucchi, P, Formenti, T, Salpietro, S, Moioli, C, Esposito, R, Bisio, L, Gori, A, Lapadula, G, Chirianni, A, Abrescia, N, De Marco, M, Baldelli, F, Belfiori, B, Parruti, G, Sozio, F, Magnani, G, Ursitti, M, Marzocchetti, A, Narciso, P, Gallo, L, Acinapura, R, Vullo, V, Lichtner, M, Tebano, G, Andreoni, M, Capozzi, M, Tozzi, V, Libertone, R, Cerilli, S, Cattelan, Am, Mura, Ms, Madeddu, G, Bonora, S, Sciandra, M, Guastavigna, M, Pellizzer, G, and Manfrin, V.
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- 2012
19. Viral tropism by geno2pheno as a tool for predicting CD4 decrease in HIV-1-infected naive patients with high CD4 counts
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Nozza, S, Canducci, F, Galli, L, Cozzi Lepri, A, Capobianchi, Mr, Ceresola, Er, Narciso, P, Libertone, R, Castelli, P, Moioli, M, D'Arminio Monforte, A, Castagna, A, Collaborators: Moroni M, ICONA F. o. u. n. d. a. t. i. o. n., Carosi, Giampiero, Cauda, R, Chiodo, F, d'Arminio Monforte, A, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Panebianco, R, Pastore, G, Perno, C, Ammassari, A, Antinori, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, M, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Montroni, M, Scalise, G, Braschi, M, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Colangeli, V, Fiorini, C, Coronado, O, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, P, Piano, P, Pizzigallo, E, D'Alessandro, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Chiodera, F, Moroni, M, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Esposito, R, Abrescia, N, Chirianni, A, De Marco, M, Viglietti, R, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, M, Arlotti, M, Ortolani, P, Antonucci, G, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, M, Lichtner, M, Carletti, F, Mura, M, Mannazzu, M, Caramello, P, Orofino, G, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
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- 2012
20. Evaluation of glomerular filtration rate in HIV-1-infected patients before and after combined antiretroviral therapy exposure
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Tordato, F, Cozzi Lepri, A, Cicconi, P, De Luca, A, Antinori, A, Colangeli, V, Castagna, A, Nasta, P, Ladisa, N, Giacometti, A, d'Arminio Monforte, A, Gori, A, ICONA Foundation Study Group: Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Ceccherini Silberstein, F, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Martellotta, F, Pastore, G, Suter, F, Chiodo, F, Fiorini, C, Coronado, O, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Chiodera, F, Castelli, P, Moroni, M, Lazzarin, A, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Abrescia, N, Chirianni, A, De Marco, M, Viglietti, R, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Antonucci, G, Narciso, P, Vullo, V, Zaccarell, M, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
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- 2011
21. Prevalence of hypovitaminosis D and factors associated with vitamin D deficiency and morbidity among HIV-infected patients enrolled in a large Italian cohort
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Vescini, F, Cozzi Lepri, A, Borderi, M, Re, Mc, Maggiolo, F, De Luca, A, Cassola, G, Vullo, V, Carosi, Giampiero, Antinori, A, Tozzi, V, Monforte, Ad, Icona Foundation Study Group: Moroni, M, Angarano, G, Carosi, G, Cauda, R, d'Arminio Monforte, A, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Perno, Cf, Viale, Pl, Von Schlosser, F, Ammassari, A, Andreoni, M, Balotta, C, Bonfanti, P, Bonora, S, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, Gargiulo, M, Gervasoni, C, Girardi, E, Lichtner, M, Lo Caputo, S, Madeddu, G, Marcotullio, S, Monno, L, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Fanti, I, Formenti, T, Montroni, M, Giacometti, A, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Verucchi, G, Piergentili, B, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Falasca, K, Carnevale, G, Lorenzotti, S, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Viscoli, G, Alessandrini, A, Piscopo, R, Mazzarello, G, Mastroianni, C, Belvisi, V, Molteni, C, Chiodera, A, Castelli, P, Rizzardini, G, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Carenzi, L, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Pastore, V, Abrescia, N, Chirianni, A, De Marco, M, Ferrari, C, Borghi, R, Baldelli, F, Belfiori, B, Parruti, G, Sozio, F, Magnani, G, Ursitti, Ma, Emilia, R, Arlotti, M, Ortolani, P, Antonucci, G, Narciso, P, Zaccarelli, M, Gallo, L, Acinapura, R, De Longis, P, Ceccarelli, L, Libertone, R, Trotta, Mp, Miccoli, A, Cattelan, Am, Mura, Ms, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
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- 2011
22. Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4+ cell count
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Marchetti, G, Cozzi Lepri, A, Merlini, E, Bellistrì, Gm, Castagna, A, Galli, M, Verucchi, G, Antinori, A, Costantini, A, Giacometti, A, di Caro, A, D'arminio Monforte, A, ICONA Foundation Study Group: Moroni, M, Angarano, G, Carosi, G, Cauda, R, d'Arminio Monforte, A, Di Perri, G, Iardino, R, Ippolito, G, Lazzarin, A, Perno, Cf, Viale, Pl, Von Schlosser, F, Ammassari, A, Andreoni, M, Balotta, C, Bonfanti, P, Bonora, S, Borderi, M, Capobianchi, Mr, Ceccherini Silberstein, F, De Luca, A, Gargiulo, M, Gervasoni, C, Girardi, E, Lichtner, M, Lo Caputo, S, Madeddu, G, Maggiolo, F, Marcotullio, S, Monno, L, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Fanti, I, Formenti, T, Montroni, M, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Piergentili, B, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Falasca, K, Carnevale, G, Lorenzotti, S, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Cassola, G, Viscoli, G, Alessandrini, A, Piscopo, R, Mazzarello, G, Mastroianni, C, Belvisi, V, Molteni, C, Chiodera, A, Castelli, P, Rizzardini, G, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Carenzi, L, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Pastore, V, Abrescia, N, Chirianni, A, De Marco, M, Ferrari, C, Borghi, R, Baldelli, F, Belfiori, B, Parruti, G, Sozio, F, Magnani, G, Ursitti, Ma, Emilia, R, Arlotti, M, Ortolani, P, Antonucci, G, Narciso, P, Tozzi, V, Vullo, V, Zaccarelli, M, Gallo, L, Acinapura, R, De Longis, P, Ceccarelli, L, Libertone, R, Trotta, Mp, Miccoli, A, Cattelan, Am, Mura, Ms, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Published
- 2011
23. Evaluation of glomerular filtration rate in HIV-1-infected patients before and after combined antiretroviral therapy exposure
- Author
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Tordato, F1, Cozzi Lepri, A, Cicconi, P, De Luca, A, Antinori, A, Colangeli, V, Castagna, A, Nasta, P, Ladisa, N, Giacometti, A, d'Arminio Monforte, A, Gori, A, Collaborators Ammassari A, ICONA Foundation Study G. r. o. u. p., Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Ceccherini Silberstein, F, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, C, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Martellotta, F, Pastore, G, Suter, F, Chiodo, F, Fiorini, C, Coronado, O, Carosi, G, Cristini, G, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Chiodera, F, Castelli, P, Moroni, M, Lazzarin, A, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Abrescia, N, Chirianni, A, De Marco, M, Viglietti, R, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Antonucci, G, Narciso, P, Vullo, Vincenzo, Zaccarell, M, Acinapura, R, De Longis, P, Trotta, Mp, Carletti, F, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Published
- 2011
24. Long-term CD4+ T-cell count evolution after switching from regimens including HIV nucleoside reverse transcriptase inhibitors (NRTI) plus protease inhibitors to regimens containing NRTI plus non-NRTI or only NRTI
- Author
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Torti, Carlo, d'Arminio Monforte, A, Pozniak, Al, Lapadula, G, Cologni, G, Antinori, A, De Luca, A, Mussini, C, Castagna, A, Cicconi, P, Minoli, L, Costantini, A, Carosi, Giampiero, Liang, H, Cesana, Bm, Master, Chelsea, Westminster, Icona, Modena, Collaborators: Carosi G, S. Raffaele HIV C. o. h. o. r. t. s., Puoti, M, Torti, C, QUIROS ROLDAN, Maria Eugenia, Paraninfo, G, Casari, S, Pastore, G, Ladisa, N, Suter, F, Maggiolo, F, Quirino, T, Migliorino, M, Ghinelli, F, Sighinolfi, L, Mazzotta, F, Lo Caputo, S, Marino, N, Angarano, A, Saracino, A, D'Arminio Monforte, A, Maserati, R, Novati, S, Tinelli, C, Antonucci, G, Ammassari, A, Cauda, R, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Martellotta, F, Minafra, G, Arici, C, Chiodo, F, Colangeli, V, Fiorini, C, Coronado, O, Carosi, G, Cristini, G, Minardi, C, Bertelli, D, Melzi, S, Manconi, Pe, Piano, P, Cosco, L, Scerbo, A, Pizzigallo, E, D'Alessandro, M, Santoro, D, Pusterla, L, Carnevale, G, Zoncada, A, Viganò, P, Mena, M, Leoncini, F, Pozzi, M, Angarano, G, Grisorio, B, Ferrara, S, Grima, P, Tundo, P, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Toti, M, Trezzi, M, Soscia, F, Tacconi, L, Orani, A, Perini, P, Scasso, A, Vincenti, A, Chiodera, F, Castelli, P, Scalzini, A, Palvarini, L, Moroni, M, Lazzarin, A, Rizzardini, G, Caggese, L, Repetto, D, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Abrescia, N, Chirianni, A, Izzo, Cm, Piazza, M, De Marco, M, Viglietti, R, Manzillo, E, Nappa, S, Colomba, A, Abbadessa, V, Prestileo, T, Mancuso, S, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Baldelli, F, Camanni, G, Petrelli, E, Cioppi, A, Alberici, F, Ruggieri, A, Menichetti, F, Martinelli, C, De Stefano, C, La Gala, A, Ballardini, G, Rizzo, E, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Dianzani, F, Ippolito, G, Ciardi, M, Narciso, P, Petrosillo, N, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Murri, R, Trotta, Mp, Noto, P, Lichtner, M, Capobianchi, Mr, Carletti, F, Perno, Cf, Girardi, E, Pezzotti, P, Rezza, G, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Orofino, Gc, Sciandra, M, Grossi, Pa, Basilico, C, Poggio, A, Bottari, G, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Resta, F, Loso, K, Cozzi Lepri, A, Borghi, V, Galli, L, Sampietro, S, Mandalia, S, and Gazzard, B.
- Published
- 2011
25. Host-specific modulation of the selective constraints driving human immunodeficiency virus type 1 env gene evolution
- Author
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Bagnarelli, P., Butini, L., Massimo Clementi, Mazzola, F., Menzo, S., Montroni, M., Bagnarelli, P., Mazzola, F., Menzo, S., Montroni, M., Butini, L., and Clementi, Massimo
- Published
- 1999
26. Incidence of malignancies in HIV-infected patients and prognostic role of current CD4 cell count: evidence from a large Italian cohort study
- Author
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Prosperi, Mc, Cozzi Lepri, A, Castagna, A, Mussini, C, Murri, R, Giacometti, A, Torti, Carlo, Costantini, A, Narciso, P, Ghinelli, F, Antinori, A, d'Arminio Monforte, A, Icona Foundation Study Group, Moroni, M, Carosi, Giampiero, Cauda, R, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Maggiolo, F, Puoti, Massimo, Torti, C, Fanti, I, Formenti, T, Montroni, M, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Pierri, A, Suter, F, Borderi, M, Verucchi, G, Piergentili, B, Carosi, G, Cristini, G, Minardi, C, Bertelli, D, Quirino, D, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Falasca, K, Carnevale, G, Lorenzotti, S, Sighinolfi, L, Leoncini, F, Pozzi, M, Pagano, G, Cassola, G, Viscoli, G, Alessandrini, A, Piscopo, R, Mazzarello, G, Soscia, F, Tacconi, L, Orani, A, Rossotti, R, Tommasi, D, Congedo, P, Chiodera, A, Castelli, P, Rizzardini, G, Schlacht, I, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Melzi, S, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Fiorino, M, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Baldelli, F, Belfiori, B, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Antonucci, G, Tozzi, V, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Calbi, M, Gallo, L, Miccoli, A, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Published
- 2010
27. Insights into reasons for discontinuation according to year of starting first regimen of highly active antiretroviral therapy in a cohort of antiretroviral-naïve patients
- Author
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Cicconi, P, Cozzi Lepri, A, Castagna, A, Trecarichi, Em, Antinori, A, Gatti, F, Cassola, G, Sighinolfi, L, Castelli, P, d'Arminio Monforte, A, Collaborators: Moroni M, ICoNA Foundation Study G. r. o. u. p., Carosi, G, Cauda, R, Chiodo, F, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Panebianco, G, Perno, Cf, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Maggiolo, F, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Montroni, M, Scalise, G, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Martellotta, G, Ladisa, N, Suter, F, Verucchi, G, Fiorini, C, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Carnevale, G, Lorenzotti, S, Ghinelli, F, Leoncini, F, Pozzi, M, Pagano, G, Viscoli, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Tommasi, D, Congedo, P, Chiodera, A, Moroni, M, Rizzardini, G, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Gori, A, Cagni, S, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Baldelli, F, Camanni, G, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Antonucci, G, Narciso, P, Tozzi, V, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, Gc, Sciandra, M, Sciandra, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Subjects
antiretroviral-naïve patients ,discontinuation of HAART - Published
- 2010
28. Predicting the risk of cardiovascular disease in HIV-infected patients: the data collection on adverse effects of anti-HIV drugs study
- Author
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Friis Møller, N, Thiébaut, R, Reiss, P, Weber, R, Monforte, Ad, De Wit, S, El Sadr, W, Fontas, E, Worm, S, Kirk, O, Phillips, A, Sabin, Ca, Lundgren, Jd, Law, Mg, Collaborators: Collins S, DAD study g. r. o. u. p., Pearce, G, Storfer, S, Rhode, R, Worm, Sw, Tverland, J, Kamara, A, Sjøl, S, Sawitz, A, Brandt, Rs, Rickenbach, M, Fanti, L, Krum, E, Gras, L, Geffard, S, Sundström, A, Delforge, M, Torres, F, Mcmanus, H, Wright, S, Kjaer, J, de Wolf, F, Zaheri, S, Bronsveld, W, Hillebrand Haverkort ME, Prins, Jm, Bos, Jc, Eeftinck Schattenkerk JK, Geerlings, Se, Godfried, Mh, Lange, Jm, van Leth FC, Lowe, Sh, van der Meer JT, Nellen, Fj, Pogány, K, van der Poll, T, Ruys, Ta, Sankatsing, Steingrover, R, van Twillert, G, van der Valk, M, van Vonderen MG, Vrouenraets, Sm, van Vugt, M, Wit, Fw, van Eeden, A, ten Veen JH, van Dam PS, Roos, Jc, Brinkman, K, Frissen, Ph, Weigel, Hm, Mulder, Jw, van Gorp EC, Meenhorst, Pl, Mairuhu, At, Veenstra, J, Danner, Sa, Van Agtmael MA, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen, M, Richter, C, van der Berg, J, van Leusen, R, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Koger, El, Bravenboer, B, ten Napel CH, Kootstra, Gj, Sprenger, Hg, Miesen, Wm, Doedens, R, Scholvinck, Eh, ten Kate RW, van Houte DP, Polee, M, Kroon, Fp, van den Broek, van Dissel JT, Schippers, Ef, Schreij, G, van de Geest, S, Verbon, A, Koopmans, Pp, Keuter, M, Post, F, van der Ven AJ, van der Ende ME, Gyssens, Ic, van der Feltz, M, den Hollander JG, de Marie, S, Nouwen, Jl, Rijnders, Bj, de Vries TE, Juttmann, Jr, van de Heul, C, van Kasteren ME, Elisabeth, S, Schneider, Mm, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Hoepelman, Im, Jaspers, Ca, Schouten, I, Schurink, Ca, Blok, Wl, Tanis, Aa, Groeneveld, Ph, Salamon, R, Beylot, J, Le Bras, M, Dupon, M, Pellegrin, Jl, Ragnaud, Jm, Dabis, F, Chêne, G, Lawson Ayayi, S, Blaizeau, Mj, Decoin, M, Delveaux, S, Hannapier, C, D'Ivernois, C, Leleux, O, Uwamaliya Nziyumvira, B, Palmer, G, Touchard, D, Jacqmin Gadda, H, Lavignolle, V, Balestre, E, Formaggio, Am, Labarerre, S, Vimard, E, Dutoit, D, Pereira, F, Boulant, B, Bonnal, F, Farbos, S, Bonarek, M, Bonnet, F, Bernard, N, Caubet, O, Cazanave, C, Dauchy, Fa, De La Taille, C, Duffau, P, Dutronc, H, Greib, C, Lacoste, D, Lafarie, S, Lazaro, E, Malvy, D, Mercié, P, Morlat, P, Neau, D, Ochoa, A, Pillot Debelleix, M, Pistone, T, Receveur, Mc, Vandenhende, Ma, Viallard, Jf, Blanco, P, Moreau, Jf, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Breilh, D, Miremont Salamé, G, Caunègre, L, Gerard, Y, Loste, P, Ceccaldi, J, Tchamgoué, S, De Witte, S, Law, M, Petoumenos, K, Moore, R, Edwards, S, Hoy, J, Watson, K, Roth, N, Nicholson, J, Bloch, M, Franic, T, Baker, D, Mcfarlane, R, Carr, A, Cooper, D, Chuah, J, Fankhauser, W, Nolan, D, Mallal, S, Forsdyke, C, Calvo, G, Mateu, S, Domingo, P, Sambeat, Ma, Gatell, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Payen, Mc, Poll, B, Van Laethem, Y, Neaton, J, Bartsch, G, El Sadr WM, Thompson, G, Wentworth, D, Luskin Hawk, R, Telzak, E, Abrams, Di, Cohn, D, Markowitz, N, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Crane, Lr, Sampson, J, Baxter, J, Mocroft, A, Ellefson, M, Phillips, An, Losso, M, Elias, C, Vetter, N, Zangerle, R, Karpov, I, Vassilenko, A, Mitsura, Vm, Suetnov, O, Colebunders, R, Vandekerckhove, L, Hadziosmanovic, V, Kostov, K, Begovac, I, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Kronborg, G, Benfield, T, Larsen, M, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Oestergaard, L, Zilmer, K, Smidt, J, Ristola, M, Katlama, C, Viard, Jp, Girard, Pm, Livrozet, Jm, Vanhems, P, Pradier, C, Rockstroh, J, Schmidt, R, van Lunzen, J, Degen, O, Stellbrink, Hj, Staszewski, S, Bogner, J, Fätkenheuer, G, Kosmidis, J, Gargalianos, P, Xylomenos, G, Perdios, J, Panos, G, Filandras, A, Karabatsaki, E, Sambatakou, H, Banhegyi, D, Mulcahy, F, Yust, I, Turner, D, Burke, M, Pollack, S, Hassoun, G, Maayan, S, Chiesi, A, Esposito, R, Mazeu, I, Mussini, C, Arici, C, Pristera, R, Mazzotta, F, Gabbuti, A, Vullo, V, Lichtner, M, Chirianni, A, Montesarchio, E, Gargiulo, M, Antonucci, G, Iacomi, F, Narciso, P, Vlassi, C, Zaccarelli, M, Lazzarin, A, Finazzi, R, Galli, M, Ridolfo, A, d'Arminio Monforte, A, Rozentale, B, Aldins, P, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Bakowska, E, Prokopowicz, D, Flisiak, R, Boron Kaczmarska, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Jablonowska, E, Malolepsza, E, Wojcik, K, Antunes, F, Valadas, E, Mansinho, K, Maltez, F, Duiculescu, D, Rakhmanova, A, Vinogradova, E, Buzunova, S, Jevtovic, D, Mokrás, M, Staneková, D, Tomazic, J, González Lahoz, J, Soriano, V, Martin Carbonero, L, Labarga, P, Moreno, S, Clotet, B, Jou, A, Paredes, R, Tural, C, Puig, J, Bravo, I, Gatell, Jm, Miró, Jm, Gutierrez, M, Mateo, G, Karlsson, A, Persson, Po, Flamholc, L, Ledergerber, B, Francioli, Cavassini, M, Hirschel, B, Boffi, E, Furrer, H, Battegay, M, Elzi, L, Kravchenko, E, Chentsova, N, Kutsyna, G, Servitskiy, S, Antoniak, S, Krasnov, M, Barton, S, Johnson, Am, Mercey, D, Johnson, Ma, Murphy, M, Weber, J, Scullard, G, Fisher, M, Leen, C, Morfeldt, L, Thulin, G, Akerlund, B, Koppel, K, Håkangård, C, Moroni, M, Antinori, A, Carosi, Giampiero, Cauda, R, Chiodo, F, Di Perri, G, Ghinelli, F, Iardino, R, Ippolito, G, Panebianco, R, Pastore, G, Perno, Cf, Pezzotti, P, Montroni, M, Scalise, G, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Maggiolo, F, Colangeli, V, Fiorini, C, Carosi, G, Cristini, G, Torti, Carlo, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Carnevale, G, Zoncada, A, Sighinolfi, L, Leoncini, F, Pozzi, M, Lo Caputo, S, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Tommasi, D, Congedo, P, Chiodera, F, Castelli, P, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Gori, A, Cagni, S, Abrescia, N, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Tozzi, V, De Luca, A, Acinapura, R, De Longis, P, Trotta, Mp, Carletti, F, Mura, Ms, Mannazzu, M, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Caissotti, C, Dellamonica, P, Bentz, L, Bernard, E, De Salvador Guillouet, F, Durant, J, Mondain Miton, V, Perbost, I, Prouvost Keller, B, Pugliese, P, Rahelinirina, V, Roger, Pm, Cua, E, Farhad, R, Ferrando, S, Vassallo, M, Baëz, E, Bernasconi, E, and Böni, J.
- Published
- 2010
29. Rate of CD4+ cell count increase over periods of viral load suppression: relationship with the number of previous virological failures
- Author
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Trotta, Mp, Cozzi Lepri, A, Ammassari, A, Vecchiet, J, Cassola, G, Caramello, P, Vullo, V, Soscia, F, Chiodera, A, Ladisa, N, Abeli, C, Cauda, R, Buonuomi, Ar, Antinori, A, d'Arminio Monforte, A, Collaborators: Moroni M, ICONA Foundation S. t. u. d. y., Carosi, Giampiero, Chiodo, F, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Panebianco, R, Pastore, G, Perno, Cf, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Martellotta, F, Suter, F, Colangeli, V, Fiorini, C, Coronado, O, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Alessandrini, A, Piscopo, R, Tacconi, L, Orani, A, Perini, P, Chiodera, F, Castelli, P, Moroni, M, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Abrescia, N, Chirianni, A, De Marco, M, Viglietti, R, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Antonucci, G, Narciso, P, Zaccarelli, M, Acinapura, R, De Longis, P, Lichtner, M, Carletti, F, Mura, Ms, Mannazzu, M, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Published
- 2010
30. High prevalence of the metabolic syndrome in HIV-infected patients: impact of different definitions of the metabolic syndrome
- Author
-
de Wolf, F, Zaheri, S, Gras, L, Bronsveld, W, Hillebrand Haverkort, Me, Prins, Jm, Bos, Jc, Eeftinck Schattenkerk, Jk, Geerlings, Se, Godfried, Mh, Lange, Jm, van Leth, Fc, Lowe, Sh, van der Meer, Jt, Nellen, Fj, Pogány, K, van der Poll, T, Reiss, P, Ruys, Ta, Steingrover, R, van Twillert, G, van der Valk, M, van Vonderen, Mg, Vrouenraets, Sm, van Vugt, M, Wit, Fw, van Eeden, A, ten Veen, Jh, van Dam, Ps, Roos, Jc, Brinkman, K, Frissen, Ph, Weigel, Hm, Mulder, Jw, van Gorp, Ec, Meenhorst, Pl, Mairuhu, At, Veenstra, J, Danner, Sa, Van Agtmael, Ma, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen, M, Richter, C, van der Berg, J, van Leusen, R, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Koger, El, Bravenboer, B, ten Napel, Ch, Kootstra, Gj, Sprenger, Hg, Miesen, Wm, Doedens, R, Scholvinck, Eh, ten Kate, Rw, van Houte, Dp, Polee, M, Kroon, Fp, van Dissel, Jt, Schippers, Ef, Schreij, G, van de Geest, S, Verbon, A, Koopmans, Pp, Keuter, M, Post, F, van der Ven, Aj, van der Ende, Me, Gyssens, Ic, van der Feltz, M, den Hollander, Jg, de Marie, S, Nouwen, Jl, Rijnders, Bj, de Vries, Te, Juttmann, Jr, van de Heul, C, van Kasteren, Me, Elisabeth, S, Schneider, Mm, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Hoepelman, Im, Jaspers, Ca, Schouten, I, Schurink, Ca, Blok, Wl, Tanis, Aa, Groeneveld, Ph, Salamon, R, Beylot, J, Dupon, M, Le Bras, M, Pellegrin, Jl, Ragnaud, Jm, Dabis, F, Chêne, G, Jacqmin Gadda, H, Thiébaut, R, Lawson Ayayi, S, Lavignolle, V, Balestre, E, Blaizeau, Mj, Decoin, M, Formaggio, Am, Delveaux, S, Labarerre, S, Uwamaliya, B, Vimard, E, Merchadou, L, Palmer, G, Touchard, D, Dutoit, D, Pereira, F, Boulant, B, Morlat, P, Bernard, N, Bonarek, M, Bonnet, F, Coadou, B, Gelie, P, Jaubert, D, Nouts, C, Lacoste, D, Dutronc, H, Cipriano, G, Lafarie, S, Chossat, I, Lacut, Jy, Leng, B, Mercie, P, Viallard, Jf, Faure, I, Rispal, P, Cipriano, C, Tchamgoué, S, Djossou, F, Malvy, D, Pivetaud, Jp, Chambon, D, De La Taille, C, Galperine, T, Neau, D, Ochoa, A, Beylot, C, Doutre, Ms, Bezian, Jh, Moreau, Jf, Taupin, Jl, Conri, C, Constans, J, Couzigou, P, Castera, L, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Trimoulet, P, Moreau, F, Mestre, C, Series, C, Taytard, A, Law, M, Petoumenos, K, Anderson, J, Cortossis, P, Hoy, J, Watson, K, Roth, N, Nicholson, J, Bloch, M, Franic, T, Baker, D, Mcfarlane, R, Carr, A, Cooper, D, Chuah, J, Fankhauser, W, Mallal, S, Forsdyke, C, Calvo, G, Torres, F, Mateu, S, Domingo, P, Sambeat, Ma, Gatell, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, De Wit, S, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Payen, Mc, Poll, B, Van Laethem, Y, Neaton, J, Bartsch, G, El Sadr, Wm, Krum, E, Thompson, G, Wentworth, D, Luskin Hawk, R, Telzak, E, Abrams, Di, Cohn, D, Markowitz, N, Arduino, R, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Crane, Lr, Sampson, J, Baxter, J, Kirk, O, Mocroft, A, Ellefson, M, Phillips, An, Lundgren, Jd, Losso, M, Elias, C, Vetter, N, Zangerle, R, Karpov, I, Vassilenko, A, Mitsura, Vm, Suetnov, O, Colebunders, R, Vandekerckhove, L, Hadziosmanovic, V, Kostov, K, Begovac, I, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Kronborg, G, Benfield, T, Larsen, M, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Oestergaard, L, Zilmer, K, Ristola, M, Katlama, C, Viard, Jp, Girard, Pm, Livrozet, Jm, Vanhems, P, Pradier, C, Rockstroh, J, Schmidt, R, van Lunzen, J, Degen, O, Stellbrink, Hj, Staszewski, S, Bogner, J, Fätkenheuer, G, Gargalianos, P, Xylomenos, G, Perdios, J, Panos, G, Filandras, A, Karabatsaki, E, Sambatakou, H, Banhegyi, D, Mulcahy, F, Yust, I, Turner, D, Burke, M, Pollack, S, Hassoun, G, Maayan, S, Chiesi, A, Esposito, R, Mazeu, I, Mussini, C, Arici, C, Pristera, R, Mazzotta, F, Gabbuti, A, Vullo, V, Lichtner, M, Chirianni, A, Montesarchio, E, Gargiulo, M, Antonucci, G, Iacomi, F, Narciso, P, Vlassi, C, Zaccarelli, M, Lazzarin, A, Finazzi, R, Galli, M, Ridolfo, A, d'Arminio Monforte, A, Rozentale, B, Aldins, P, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Bakowska, E, Prokopowicz, D, Flisiak, R, Boron Kaczmarska, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Jablonowska, E, Malolepsza, E, Wojcik, K, Antunes, F, Valadas, E, Maltez, F, Duiculescu, D, Rakhmanova, A, Vinogradova, E, Buzunova, S, Jevtovic, D, Mokrás, M, Staneková, D, Tomazic, J, González Lahoz, J, Soriano, V, Martin Carbonero, L, Labarga, P, Clotet, B, Jou, A, Paredes, R, Tural, C, Puig, J, Bravo, I, Gatell, Jm, Miró, Jm, Gutierrez, M, Mateo, G, Karlsson, A, Persson, Po, Flamholc, L, Ledergerber, B, Weber, R, Cavassini, M, Hirschel, B, Boffi, E, Furrer, H, Battegay, M, Elzi, L, Kravchenko, E, Chentsova, N, Kutsyna, G, Servitskiy, S, Antoniak, S, Krasnov, M, Barton, S, Johnson, Am, Mercey, D, Phillips, A, Johnson, Ma, Murphy, M, Weber, J, Scullard, G, Fisher, M, Leen, C, Morfeldt, L, Thulin, G, Sundström, A, Akerlund, B, Koppel, K, Håkangård, C, Moroni, M, Carosi, Giampiero, Cauda, R, Chiodo, F, Di Perri, G, Iardino, R, Ippolito, G, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Antinori, A, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, Cozzi Lepri, A, De Luca, A, Gervasoni, C, Girardi, E, Maggiolo, F, Murri, R, Puoti, M, Torti, C, Fanti, I, Formenti, T, Prosperi, M, Montroni, M, Giacometti, A, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Verucchi, G, Fiorini, C, Carosi, G, Cristini, G, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Vecchiet, J, Farenga, M, Carnevale, G, Lorenzotti, S, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Pagano, G, Cassola, G, Viscoli, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Rossotto, R, Tommasi, D, Congedo, P, Chiodera, A, Castelli, P, Rizzardini, G, Schlacht, I, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Melzi, S, Moioli, Mc, Cicconi, P, Gori, A, Abrescia, N, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Baldelli, F, Camanni, G, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Tozzi, V, Acinapura, R, De Longis, P, Trotta, Mp, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, Gc, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Fontas, E, Caissotti, C, Dellamonica, P, Bentz, L, Bernard, E, Cua, E, De Salvador Guillouet, F, Durant, J, Farhad, R, Ferrando, S, Mondain Miton, V, Perbost, I, Prouvost Keller, B, Pugliese, P, Rahelinirina, V, Roger, Pm, Vassallo, M, Baëz, E, Bernasconi, E, Böni, J, Bucher, H, Bürgisser, P, Cattacin, S, Dubs, R, Egger, M, Erb, P, Fischer, M, Flepp, M, Fontana, A, Francioli, P, Furrer, Hj, Gorgievski, M, Günthard, H, Kaiser, L, Kind, C, Klimkait, T, Lauper, U, Opravil, M, Paccaud, F, Pantaleo, G, Perrin, L, Piffaretti, Jc, Rickenbach, M, Rudin, C, Schmid, P, Schüpbach, J, Speck, R, Telenti, A, Trkola, A, Vernazza, P, and Yerly, S.
- Subjects
HIV ,metabolic syndrome - Published
- 2010
31. Viral interference between hepatitis B, C, and D viruses in dual and triple infections in HIV-positive patients
- Author
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Ancarani, F, Antinori, A, Antonucci, G, Bruno, R, Capobianchi, M, Cingolani, A, Cozzi Lepri, A, d'Arminio Monforte, A, Galli, M, Girardi, E, Marino, N, Morsica, G, Narciso, P, Pastecchia, C, Pizzaferri, P, Puoti, M, Santantonio, T, Verucchi, G, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, De Luca, A, Gervasoni, C, Lo Caputo, S, Murri, R, Mussini, C, Torti, C, Moroni, M, Carosi, Giampiero, Cauda, R, Chiodo, F, Di Perri, G, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Pastore, G, Perno, Cf, Montroni, M, Scalise, G, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Maggiolo, F, Colangeli, V, Fiorini, C, Carosi, G, Cristini, G, Minardi, C, Bertelli, D, Quirino, T, Manconi, P, Piano, P, Pizzigallo, E, Dalessandro, M, Carnevale, G, Zoncada, A, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Tommasi, D, Congedo, P, Chiodera, F, Castelli, P, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Moioli, M, Esposito, R, Gori, A, Cagni, S, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Filice, G, Magnani, G, Ursitti, M, Arlotti, M, Ortolani, P, Andreoni, M, Tozzi, V, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, M, Lichtner, M, Carletti, F, Mura, M, Mannazzu, M, Caramello, P, Orofino, G, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Subjects
HDV ,HCV ,HBV ,HIV - Published
- 2009
32. Risk of developing specific AIDS-defining illnesses in patients coinfected with HIV and hepatitis C virus with or without liver cirrhosis
- Author
-
d'Arminio Monforte, A, Cozzi Lepri, A, Castagna, A, Antinori, A, De Luca, A, Mussini, C, Caputo, Sl, Arlotti, M, Magnani, G, Pellizzer, G, Maggiolo, F, Puoti, M, Collaborators: Moroni M, Icona Foundation Study G. r. o. u. p., Carosi, Giampiero, Cauda, R, Cauda, F, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Balotta, C, Bonfanti, P, Capobianchi, Mr, Ceccherini Silberstein, F, Cozzi Lepri, C, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Torti, Carlo, Fanti, I, Formenti, T, Prosperi, M, Montroni, M, Giacometti, A, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Chiodo, F, Verucchi, G, Fiorini, C, Carosi, G, Cristini, C, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Pizzigallo, E, Dalessandro, M, Carnevale, G, Lorenzotti, S, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Pagano, G, Cassola, G, Viscoli, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Rossotto, R, Tommasi, D, Congedo, P, Chiodera, A, Castelli, P, Rizzardini, G, Schlacht, I, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Melzi, S, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Borrello, A, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Baldelli, F, Camanni, G, Ursitti, Ma, Ortolani, P, Andreoni, M, Antonucci, G, Narciso, P, Tozzi, V, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, G, Raise, E, Ebo, F, and Buonfrate, D.
- Published
- 2009
33. Mortality from HIV and TB coinfections is higher in Eastern Europe than in Western Europe and Argentina
- Author
-
Podlekareva, Dn, Mocroft, A, Post, Fa, Riekstina, V, Miro, Jm, Furrer, H, Bruyand, M, Panteleev, Am, Rakhmanova, Ag, Girardi, E, Losso, Mh, Toibaro, Jj, Caylá, J, Miller, Rf, Obel, N, Skrahina, A, Chentsova, N, Lundgren, Jd, Kirk, O, Collaborators: Losso MH, HIV/TB Study Writing G. r. o. u. p., Warley, E, Tamayo, N, Cristina Ortiz, M, Santojanni, F, Scapelatto, P, Bottaro, E, Murano, F, Miachans, M, Contarelli, J, Massera, L, Corral, J, Hualde, M, Miglioranza, C, Corti, M, Metta, H, Casiró, A, Cuini, R, Laplume, H, David, D, Marson, C, Lupo, S, Trape, L, Garcia Messina, O, Gear, O, Ramos Mejía JM, Bruguera, Jm, Karpov, I, Vasilenko, A, Skrahina, E, Skrahin, A, Zhavoronok, S, Mitsura, V, Ruzanov, D, Bondarenko, V, Suetnov, O, Paduto, D, Gerstoft, J, Kronborg, G, Pedersen, C, Larsen, Cs, Pedersen, G, Laursen, Al, Nielsen, L, Jensen, J, Dabis, F, Chêne, G, Lawson Ayayi, S, Thiébaut, R, Winnock, M, Bernard, N, Dupon, M, Lacoste, D, Malvy, D, Mercié, P, Morlat, P, Neau, D, Pellegrin, Jl, Ragnaud, Jm, Moreau, Jf, Blanco, P, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Blaizeau, Mj, Decoin, M, Delveaux, S, Dutoit, D, Geffard, S, Hannapier, C, Houinou, L, Labarrère, S, Lavignolle Aurillac, V, Palmer, G, Touchard, D, Bonarek, M, Bonnet, F, Lacombe, K, Gellie, P, Paccalin, F, Pertusa, Mc, Dutronc, H, Dauchy, F, Lafarie, S, Longy Boursier, M, Pistonne, T, Receveur, Mc, Thibaut, P, Cazorla, C, Chambon, D, De La Taille, C, Galpérine, T, Ochoa, A, Viallard, Jf, Caubet, O, Nouts, C, Couzigou, P, Castera, L, Loste, P, Caunègre, L, Bonnal, F, Farbos, S, Gemain, Mc, Ceccaldi, J, Tchamgoue, S, Witte, Sd, Carvalho, Ac, Basché, R, Hamad, Ie, Ricci, Ba, Maggiolo, F, Ravasio, V, Mussini, C, Prati, F, Castelletti, S, Spallanzani, L, Antinori, A, Antonucci, G, Bibbolino, C, Bove, G, Busi Rizzi, E, Cicalini, S, Conte, A, Cuzzi, G, De Mori, P, Festa, A, Goletti, D, Grisetti, S, Gualano, G, Lauria, Fn, Maddaluno, R, Migliorisi Ramazzini, P, Narciso, P, Parracino, L, Palmieri, F, Petrosillo, N, Pucillo, L, Puro, V, Vanacore, P, Urso, R, Moroni, M, Carosi, Giampiero, Cauda, R, Chiodo, F, d'Arminio Monforte, A, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Mazzotta, F, Panebianco, R, Pastore, G, Perno, Cf, Ammassari, A, Arici, C, Balotta, C, Bonfanti, P, Capobianchi, Mr, Castagna, A, Ceccherini Silberstein, F, Cozzi Lepri, A, De Luca, A, Gervasoni, C, Lo Caputo, S, Murri, R, Puoti, Massimo, Torti, Carlo, Fanti, I, Formenti, T, Prosperi, M, Montroni, M, Giacoemtti, A, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Verucchi, G, Fiorini, C, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Pizzigallo, E, Dalessandro, M, Carnevale, G, Lorenzotti, S, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Pagano, G, Cassola, G, Viscoli, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Rossotto, R, Tommasi, D, Congedo, P, Chiodera, A, Castelli, P, Rizzardini, G, Schlacht, I, Ridolfo, Al, Foschi, A, Salpietro, S, Merli, S, Melzi, S, Moioli, Mc, Cicconi, P, Esposito, R, Gori, A, Borrello, A, Abrescia, N, Chirianni, A, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Baldelli, F, Camanni, G, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Tozzi, V, Vullo, V, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Ms, Madeddu, G, Caramello, P, Orofino, Gc, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Aldins, P, Duiculescu, D, Rakhmanova, A, Malashenkov, E, Kozlov, A, Panteleev, A, Buzunova, S, García Goez JF, Moreno Camacho, A, Martínez, Ja, González, J, García Alcaide, F, de Lazzari, E, Gatell, Jm, Sanchez, P, Lopez Colomes JL, Martínez Lacasa, X, Falcó, V, Imaz, A, Ocaña, I, Vidal, R, Sambeat, Ma, Caylà, J, Moreno Martínez, A, Orcau, A, Weber, R, Battegay, M, Hirschel, B, Cavassini, M, Bernasconi, E, Schmid, P, Rickenbach, M, Post, F, Campbell, L, Miller, R, Arenas Pinto, A, Podlekareva, D, Kjaer, J, Ellefson, M, and Toibaro, J. J.
- Subjects
HIV/TB coinfection ,Eastern Europe ,Western Europe ,Argentina - Published
- 2009
34. Does short-term virologic failure translate to clinical events in antiretroviral-naïve patients initiating antiretroviral therapy in clinical practice?
- Author
-
Antiretroviral Therapy Cohort Collaboration, Mugavero, Mj, May, M, Harris, R, Saag, Ms, Costagliola, D, Egger, M, Phillips, A, Günthard, Hf, Dabis, F, Hogg, R, de Wolf, F, Fatkenheuer, G, Gill, Mj, Justice, A, D'Arminio Monforte, A, Lampe, F, Miró, Jm, Staszewski, S, Collaborators: Casabona J, Sterne J. A., Geneviè, C, del Amo, J, Fätkenheuer, G, Gill, J, Guest, J, Kitahata, M, Ledergerber, B, Mocroft, A, Reiss, P, Saag, M, Sterne, J, Sterne, Ja, Abgrall, S, Barin, F, Bentata, M, Billaud, E, Boué, F, Burty, C, Cabié, A, Cotte, L, De Truchis, P, Duval, X, Duvivier, C, Enel, P, Fredouille Heripret, L, Gasnault, J, Gaud, C, Gilquin, J, Grabar, S, Katlama, C, Khuong, Ma, Lang, Jm, Lascaux, As, Launay, O, Mahamat, A, Mary Krause, M, Matheron, S, Meynard, Jl, Pavie, J, Pialoux, G, Pilorgé, F, Poizot Martin, I, Pradier, C, Reynes, J, Rouveix, E, Simon, A, Tattevin, P, Tissot Dupon, H, Viard, Jp, Viget, N, Pariente Khayat, A, Salomon, V, Jacquemet, N, Rivet, A, Abgral, S, Guiguet, M, Kousignian, I, Lanoy, E, Lièvre, L, Potard, V, Selinger Leneman, H, Bouvet, E, Crickx, B, Ecobichon, Jl, Leport, C, Picard Dahan, C, Yeni, P, Tisne Dessus, D, Weiss, L, Salmon, D, Sicard, D, Auperin, I, Roudière, L, Fior, R, Delfraissy, Jf, Goujard, C, Jung, C, Lesprit, P, Desplanque, N, Meyohas, Mc, Picard, O, Cadranel, J, Mayaud, C, Bricaire, F, Herson, S, Clauvel, Jp, Decazes, Jm, Gerard, L, Molina, Jm, Diemer, M, Sellier, P, Berthé, H, Dupont, C, Chandemerle, C, Mortier, E, de Truchis, P, Honoré, P, Jeantils, V, Tassi, S, Mechali, D, Taverne, B, Gourdon, F, Laurichesse, H, Fresard, A, Lucht, F, Eglinger, P, Faller, Jp, Bazin, C, Verdon, R, Boibieux, A, Peyramond, D, Livroze, Jm, Touraine, Jl, Trepo, C, Ravaux, I, Tissot Dupont, H, Delmont, Jp, Moreau, J, Gastaut, Ja, Retornaz, F, Soubeyrand, J, Allegre, T, Blanc, Pa, Galinier, A, Ruiz, Jm, Lepeu, G, Granet Brunello, P, Esterni, Jp, Pelissier, L, Cohen Valensi, R, Nezri, M, Chadapaud, S, Laffeuillade, A, Laffeuillade, J, May, T, Rabaud, C, Raffi, F, Pugliese, P, Arvieux, C, Michelet, C, Borsa Lebas, F, Caron, F, Fraisse, P, Rey, D, Arlet Suau, E, Cuzin, L, Massip, P, Thiercelin Legrand MF, Yasdanpanah, Y, Pradinaud, R, Sobesky, M, Contant, M, Montroni, M, Scalise, G, Braschi, Mc, Riva, A, Tirelli, U, Cinelli, R, Pastore, G, Ladisa, N, Suter, F, Arici, C, Chiodo, F, Colangeli, V, Fiorini, C, Carosi, Giampiero, Cristini, G, Torti, Carlo, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Cosco, L, Scerbo, A, Vecchiet, J, D'Alessandro, M, Santoro, D, Pusterla, L, Carnevale, G, Zoncada, A, Viganò, P, Mena, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Lo Caputo, S, Angarano, G, Grisorio, B, Saracino, A, Ferrara, S, Grima, P, Grima, F, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Toti, M, Trezzi, M, Soscia, F, Tacconi, L, Orani, A, Perini, P, Scasso, A, Vincenti, A, Chiodera, F, Castelli, P, Scalzini, A, Palvarini, L, Moroni, M, Lazzarin, A, Rizzardini, G, d'Arminio Monforte, A, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Mussini, C, Abresci, N, Chirianni, A, Izzo, Cm, Piazza, M, De Marco, M, Viglietti, R, Manzillo, E, Nappa, S, Colomba, A, Abbadessa, V, Prestileo, T, Mancuso, S, Ferrari, C, Pizzaferri, P, Filice, G, Minoli, L, Bruno, R, Novati, S, Baldelli, F, Tinca, M, Petrelli, E, Cioppi, A, Cioppi, F, Ruggieri, A, Menichetti, F, Martinelli, C, De Stefano, C, La Gala, A, Ballardini, G, Rizzo, E, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Dianzani, F, Ippolito, G, Antinori, A, Antonucci, G, Ciardi, M, Narciso, P, Petrosillo, N, Vullo, V, De Luca, A, Zaccarelli, M, Acinapura, R, De Longis, P, Brandi, A, Trotta, Mp, Noto, P, Lichtne, M, Capobianch, Mr, Carletti, F, Girardi, E, Pezzotti, P, Rezza, G, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Sciandra, M, Orofino, Gc, Grossi, Pa, Basilico, C, Poggio, A, Bottari, G, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Resta, F, Loso, K, Cozzi Lepri, A, Battegay, M, Bernasconi, E, Böni, J, Bucher, Hc, Bürgisser, P, Calmy, A, Cattacin, S, Cavassini, M, Dubs, R, Elzi, L, Fischer, M, Flepp, M, Fontana, A, Francioli, P, Furrer, H, Fux, C, Gorgievski, M, Günthard, H, Hirsch, H, Hirschel, B, Hösli, I, Kahlert, Ch, Kaiser, L, Karrer, U, Kind, C, Klimkait, T, Martinetti, G, Martinez, B, Martinez, N, Nadal, D, Opravil, M, Paccaud, F, Pantaleo, G, Rauch, A, Regenass, S, Rickenbach, M, Rudin, C, Schmid, P, Schultze, D, Schüpbach, J, Speck, R, Taffé, P, Telenti, A, Trkola, A, Vernazza, P, Weber, R, Yerly, S, Gras, La, van Sighem AI, Smit, C, Prins, Jm, Branger, J, Eeftinck Schattenkerk JK, Gisolf, J, Godfried, Mh, Lange, Jm, Lettinga, Kd, van der Meer JT, Nellen, Fj, van der Poll, T, Ruys, Ta, Steingrover, R, Vermeulen, Jn, Vrouenraets, Sm, van Vugt, M, Wit, Fw, Kuijpers, Tw, Pajkrt, D, Scherpbier, Hj, van Eeden, A, Brinkman, K, van den Berk GE, Blok, Wl, Frissen, Ph, Roos, Jc, Schouten, We, Mulder, Jw, van Gorp EC, Wagenaar, J, Veenstra, J, Danner, Sa, Van Agtmael MA, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen MG, Richter, C, van der Berg, J, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Pogány, K, Bravenboer, B, Sprenger, Hg, van Assen, S, van Leeuwen JT, Doedens, R, Scholvinck, Eh, ten Kate RW, Soetekouw, R, van Houte, D, Polée, Mb, Kroon, Fp, van den Broek PJ, van Dissel JT, Schippers, Ef, Schreij, G, van der Geest, S, Lowe, S, Verbon, A, Koopmans, Pp, Van Crevel, R, de Groot, R, Keuter, M, Post, F, van der Ven AJ, Warris, A, van der Ende ME, Gyssens, Ic, van der Feltz, M, Nouwen, Jl, Rijnders, Bj, de Vries TE, Driessen, G, van der Flier, M, Hartwig, Ng, Juttman, Jr, van Kasteren ME, Van de Heul, C, Hoepelman, Im, Schneider, Mm, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Jaspers, Ca, Mudrikove, T, Schurink, Ca, Gisolf, Eh, Geelen, Sp, Wolfs, Tf, Faber, T, Tanis, Aa, Groeneveld, Ph, den Hollander JG, Duits, Aj, Winkel, K, Back, Nk, Bakker, Me, Berkhout, B, Jurriaans, S, Zaaijer, Hl, Cuijpers, T, Rietra, Pj, Roozendaal, Kj, Pauw, W, van Zanten AP, Smits, Ph, von Blomberg BM, Savelkoul, P, Pettersson, A, Swanink, Cm, Franck, Pf, Lampe, As, Jansen, Cl, Hendriks, R, Benne, Ca, Veenendaal, D, Storm, H, Weel, J, van Zeijl JH, Kroes, Ac, Claas, Hc, Bruggeman, Ca, Goossens, Vj, Galama, Jm, Melchers, Wj, Poort, Ya, Doornum, Gj, Niesters, Mg, Osterhaus, Ad, Schutten, M, Buiting, Ag, Swaans, Ca, Boucher, Ca, Schuurman, R, Boel, E, Jansz, Af, Veldkamp, A, Beijnen, Jh, Huitema, Ad, Burger, Dm, Hugen, Pw, van Kan HJ, Losso, M, Duran, A, Vetter, N, Karpov, I, Vassilenko, A, Clumeck, N, De Wit, S, Poll, B, Colebunders, R, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Lundgren, J, Benfield, T, Kirk, O, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Zilmer, K, Girard, Pm, Saint Marc, T, Vanhems, P, Dietrich, M, Manegold, C, van Lunzen, J, Stellbrink, Hj, Staszewsk, S, Bickel, M, Goebel, Fd, Rockstroh, J, Schmidt, R, Kosmidis, J, Gargalianos, P, Sambatakou, H, Perdios, J, Panos, G, Filandras, A, Karabatsaki, E, Banhegyi, D, Mulcahy, F, Yust, I, Turner, D, Burke, M, Pollack, S, Hassoun, G, Sthoeger, Z, Maayan, S, Chiesi, A, Borghi, R, Pristera, R, Mazzott, F, Gabbuti, A, Vullo, Lichtner, M, Montesarchio, E, Iacomi, F, Finazzi, R, Viksna, L, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Prokopowicz, D, Wiercinska Drapalo, A, Boron Kaczmarska, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Antunes, F, Valadas, E, Mansinho, K, Matez, F, Duiculescu, D, Babes, V, Streinu Cercel, A, Vinogradova, E, Rakhmanova, A, Jevtovic, D, Mokrás, M, Staneková, D, González Lahoz, J, Sánchez Conde, M, García Benayas, T, Martin Carbonero, L, Soriano, V, Clotet, B, Jou, A, Conejero, J, Tural, C, Gatell, Jm, Blaxhult, A, Karlsson, A, Pehrson, P, Soravia Dunand, V, Kravchenko, E, Chentsova, N, Barton, S, Johnson, Am, Mercey, D, Johnson, Ma, Murphy, M, Weber, J, Scullard, G, Fisher, M, Brettle, R, Loveday, C, Gatell, J, Johnson, A, Vella, S, Gjørup, I, Friis Moeller, N, Bannister, W, Mollerup, D, Podlevkareva, D, Holkmann Olsen, C, Kjaer, J, Raffanti, S, Dieterch, D, Becker, S, Scarsella, A, Fusco, G, Most, B, Balu, R, Rana, R, Beckerman, R, Ising, T, Fusco, J, Irek, R, Johnson, B, Hirani, A, Dejesus, E, Pierone, G, Lackey, P, Irek, C, Burdick, J, Leon, S, Arch, J, Helm, Eb, Carlebach, A, Müller, A, Haberl, A, Nisius, G, Lennemann, T, Stephan, C, Mösch, M, Gute, P, Locher, L, Lutz, T, Klauke, S, Knecht, G, Khaykin, P, Doerr, Hw, Stürmer, M, Babacan, E, von Hentig, N, Beylot, J, Chêne, G, Dupon, M, Longy Boursier, M, Pellegrin, Jl, Ragnaud, Jm, Salamon, R, Thiébaut, R, Lewden, C, Lawson Ayayi, S, Mercié, P, Moreau, Jf, Morlat, P, Bernard, N, Lacoste, D, Malvy, D, Neau, D, Blaizeau, Mj, Decoin, M, Delveaux, S, Hannapier, C, Labarrère, S, Lavignolle Aurillac, V, Uwamaliya Nziyumvira, B, Palmer, G, Touchard, D, Balestre, E, Alioum, A, Jacqmin Gadda, H, Bonarek, M, Bonnet, F, Coadou, B, Gellie, P, Nouts, C, Bocquentin, F, Dutronc, H, Lafarie, S, Aslan, A, Pistonne, T, Thibaut, P, Vatan, R, Chambon, D, De La Taille, C, Cazorla, C, Ocho, A, Viallard, Jf, Caubet, O, Cipriano, C, Lazaro, E, Couzigou, P, Castera, L, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Breilh, D, Blanco, P, Loste, P, Caunègre, L, Bonna, F, Farbos, S, Ferrand, M, Ceccaldi, J, Tchamgoué, S, De Witte, S, Buy, E, Akagi, L, Brandson, E, Druyts, E, Gataric, Kf, Harrigan, Pr, Harris, M, Hayden, A, Lima, V, Montaner, J, Moore, D, Wood, E, Yip, B, Zhang, W, Bhagani, S, Byrne, P, Carroll, A, Cuthbertson, Z, Dunleavy, A, Geretti, Am, Heelan, B, Johnson, M, Kinloch de Loes, S, Lipman, M, Madge, S, Marshall, N, Nair, D, Nebbia, G, Prinz, B, Swaden, L, Tyrer, M, Youle, M, Chaloner, C, Grabowska, H, Holloway, J, Puradiredja, J, Ransom, D, Tsintas, R, Bansi, L, Fox, Z, Harris, E, Hill, T, Lodwick, R, Reekie, J, Sabin, C, Smith, C, Amoah, E, Booth, C, Clewley, G, Garcia Diaz, A, Gregory, B, Labbett, W, Tahami, F, Thomas, M, Read, R, Krentz, H, Beckthold, B, Faetkenheuer, G, Casabona, J, Miró, Jl, Alquézar, A, Esteve, A, Podzamczer, D, Murillas, J, Romero, A, Agustí, C, Agüero, F, Ferrer, E, Riera, M, Segura, F, Segura, G, Force, L, Vilaró, J, Masabeu, A, García, I, Guadarrama, M, Montoliu, A, Ortega, N, Lazzari, E, Puchol, E, Sanchez, M, Blanco, Jl, Garcia Alcaide, F, Martinez, E, Mallolas, J, López Dieguez, M, García Goez JF, Sirera, G, Romeu, J, Negredo, E, Miranda, C, Capitan, Mc, Olmo, M, Barragan, P, Saumoy, M, Bolaof, F, Cabellos, C, Peña, C, Sala, M, Cervantes, M, Amengual, Mj, Navarro, M, Penelo, E, Barrufet, P, Willig, Jh, Raper, Jl, Allison, Jj, Kempf, Mc, Schumacher, Je, Wes, Ao, Lin, Hy, Pisu, M, Moneyham, L, Vance, D, Bachmann, L, Davies, Sl, Berner, E, Acosta, E, King, J, Savage, K, Nevin, C, Walton, Fb, Marler, Ml, Lawrence, S, Files Kennedy, B, Batey, Ds, Patil, Ma, Patil, U, Varshney, M, Gibson, E, Guzman, A, Rinehart, D, Justice, Ac, Fiellin, Da, Bryant, K, Rimland, D, Jones Taylor, C, Oursler, Ka, Titanji, R, Brown, S, Garrison, S, Rodriguez Barradas, M, Masozera, N, Goetz, M, Leaf, D, Simberkoff, M, Blumenthal, D, Leung, J, Butt, A, Hoffman, E, Gibert, C, Peck, R, Mattocks, K, Braithwaite, S, Brandt, C, Cook, R, Conigliaro, J, Crothers, K, Chang, J, Crystal, S, Day, N, Erdos, J, Freiberg, M, Kozal, M, Gaziano, M, Gerschenson, M, Good, B, Gordon, A, Goulet, J, Kraemer, K, Lim, J, Maisto, S, Miller, P, O'Connor, P, Papas, R, Rinaldo, C, Roberts, M, Samet, J, Cohen, D, Consorte, A, Gordon, K, Kidwai, F, Levin, F, Mcginnis, K, Rambo, M, Rogers, J, Skanderson, M, and Whitsett, F.
- Published
- 2008
35. Genetic polymorphisms differently influencing the emergence of atrophy and fataccumulation in HIV-related lipodystrophy
- Author
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Zanone Poma, B, Riva, A, Nasi, M, Cicconi, P, Broggini, V, Lepri, Ac, Mologni, D, Mazzotta, F, Monforte, Ad, Mussini, C, Cossarizza, A, Galli, M, Collaborators: Montroni M, Icona Foundation Study G. r. o. u. p., Scalise, G, Tirelli, U, Martellotta, F, Pastore, G, Ladisa, N, Suter, F, Maggiolo, F, Chiodo, F, Colangeli, V, Fiorini, C, Carosi, G, Cristini, G, Torti, Carlo, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Carnevale, G, Zoncada, A, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Lo Caputo, S, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Tommasi, D, Congedo, P, Chiodera, F, Castelli, P, Moroni, M, Lazzarin, A, Rizzardini, G, Caggese, L, d'Arminio Monforte, A, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Gori, A, Cagni, S, Abrescia, N, Chirianni, A, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Andreoni, M, Antinori, A, Antonucci, G, Narciso, P, Tozzi, V, Vullo, V, De Luca, A, Zaccarelli, M, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, and Buonfrate, D.
- Published
- 2008
36. HIV-induced immunodeficiency and mortality from AIDS-defining and non-AIDS-defining malignancies
- Author
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Monforte, A, Abrams, D, Pradier, C, Weber, R, Reiss, P, Bonnet, F, Kirk, O, Law, M, De Wit, S, Friis Møller, N, Phillips, An, Sabin, Ca, Lundgren, Jd, Collaborators: Collins S, Data Collection on Adverse Events of Anti HIV Drugs Study G. r. o. u. p., Loeliger, E, Tressler, R, Weller, I, Worm, Sw, Sjøl, A, Sawitz, A, Rickenbach, M, Pezzotti, P, Krum, E, Gras, L, Balestre, E, Sundström, A, Poll, B, Fontas, E, Torres, F, Petoumenos, K, Kjaer, J, de Wolf, F, Zaheri, S, Bronsveld, W, Hillebrand Haverkort ME, Prins, Jm, Bos, Jc, Schattenkerk, Jk, Geerlings, Se, Godfried, Mh, Lange, Jm, van Leth FC, Lowe, Sh, van der Meer JT, Nellen, Fj, Pogány, K, van der Poll, T, Ruys, Ta, Sankatsing, Sr, van Twillert, G, van der Valk, M, van Vonderen MG, Vrouenraets, Sm, van Vugt, M, Wit, Fw, van Eeden, A, ten Veen JH, van Dam PS, Roos, Jc, Brinkman, K, Frissen, Ph, Weigel, Hm, Mulder, Jw, van Gorp EC, Meenhorst, Pl, Mairuhu, At, Veenstra, J, Danner, Sa, Van Agtmael MA, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen, M, Richter, C, van der Berg, J, van Leusen, R, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Koger, El, Bravenboer, B, ten Napel CH, Kootstra, Gj, Sprenger, Hg, Miesen, Wm, Doedens, R, Scholvinck, Eh, ten Kate RW, van Houte DP, Polee, M, Kroon, Fp, van den Broek, van Dissel JT, Schippers, Ef, Schreij, G, van de Geest, S, Verbon, A, Koopmans, Pp, Keuter, M, Post, F, van der Ven AJ, van der Ende ME, Gyssens, Ic, van der Feltz, M, den Hollander JG, de Marie, S, Nouwen, Jl, Rijnders, Bj, de Vries TE, Juttmann, Jr, van de Heul, C, van Kasteren ME, St Elisabeth SM, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Hoepelman, Im, Jaspers, Ca, Schouten, I, Schurink, Ca, Blok, Wl, Tanis, Aa, Groeneveld, Ph, Salamon, R, Beylot, J, Dupon, M, Le Bras, M, Pellegrin, Jl, Ragnaud, Jm, Dabis, F, Chêne, G, Jacqmin Gadda, H, Thiébaut, R, Lawson Ayayi, S, Lavignolle, V, Blaizeau, Mj, Decoin, M, Formaggio, Am, Delveaux, S, Labarerre, S, Uwamaliya, B, Vimard, E, Merchadou, L, Palmer, G, Touchard, D, Dutoit, D, Pereira, F, Boulant, B, Morlat, P, Bernard, N, Bonarek, M, Coadou, B, Gelie, P, Jaubert, D, Nouts, C, Lacoste, D, Dutronc, H, Cipriano, G, Lafarie, S, Chossat, I, Lacut, Jy, Leng, B, Mercié, P, Viallard, Jf, Faure, I, Rispal, P, Cipriano, C, Tchamgoué, S, Djossou, F, Malvy, D, Pivetaud, Jp, Chambon, D, De La Taille, C, Galperine, T, Neau, D, Ochoa, A, Beylot, C, Doutre, Ms, Bezian, Jh, Moreau, Jf, Taupin, Jl, Conri, C, Constans, J, Couzigou, P, Castera, L, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Trimoulet, P, Moreau, F, Mestre, C, Series, C, Taytard, A, Glenday, K, Anderson, J, Cortissos, P, Mijch, A, Watson, K, Roth, N, Nicolson, J, Bloch, M, Agrawal, S, Franic, T, Baker, D, Vale, R, Carr, A, Cooper, D, Lacey, M, Hesse, K, Chuah, J, Lester, D, Fankhauser, W, Mallal, S, Forsdyke, C, Bulgannawar, S, Calvo, G, Mateu, S, Domingo, P, Sambeat, Ma, Gatell, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Payen, Mc, Van Laethem, Y, Neaton, J, Bartsch, G, El Sadr WM, Thompson, G, Wentworth, D, Luskin Hawk, R, Telzak, E, Abrams, Di, Cohn, D, Markowitz, N, Arduino, R, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Crane, Rl, Sampson, J, Baxter, J, Olsen, Ch, Mocroft, A, Vetter, N, Karpov, I, Vassilenko, A, Colebunders, R, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Benfield, T, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Zilmer, K, Katlama, C, Viard, Jp, Girard, Pm, Saint Marc, T, Vanhems, P, Dietrich, M, Manegold, C, van Lunzen, J, Stellbrink, Hj, Staszewski, S, Bieckel, M, Goebel, Fd, Fätkenheuer, C, Rockstroh, J, Schmidt, Re, Kosmidis, J, Gargalianos, P, Sambatakou, H, Perdios, J, Panos, G, Filandras, A, Banhegyi, D, Mulcahy, F, Yust, I, Burke, M, Turner, D, Pollack, S, Hassoun, J, Sthoeger, Z, Maayan, S, Vella, S, Chiesi, A, Arici, C, Pristerá, R, Mazzotta, F, Gabbuti, A, Esposito, R, Bedini, A, Chirianni, A, Montesarchio, E, Vullo, V, Santopadre, P, Narciso, P, Antinori, A, Franci, P, Zaccarelli, M, Lazzarin, A, Castagna, A, Viksna, L, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Prokopowicz, D, Wiercinska Drapalo, A, Boron Kaczmarska, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Antunes, F, Mansinho, K, Maltez, F, Duiculescu, D, Babes, V, Streinu Cercel, A, Vinogradova, E, Rakhmanova, A, Jevtovic, D, Mokrás, M, Staneková, D, González Lahoz, J, Sanchez Conde, M, García Benayas, T, Martin Carbonero, L, Soriano, V, Clotet, B, Jou, A, Conejero, J, Ruiz, L, Tural, C, Gatell, Jm, Miró, Jm, Zamora, L, Blaxhult, A, Karlsson, A, Pehrson, P, Ledergerber, B, Francioli, P, Telenti, A, Hirschel, B, Soravia Dunand, V, Furrer, H, Kravchenko, E, Chentsova, N, Fisher, M, Brettle, R, Barton, S, Johnson, Am, Mercey, D, Murphy, M, Johnson, Ma, Weber, J, Scullard, G, Morfeldt, L, Thulin, G, Akerlund, B, Koppel, K, Flamholc, L, Håkangård, C, Ammassari, A, Maggiolo, F, Balotta, C, Bonfanti, P, Capobianchi, M, Ceccherini Silberstein, F, Cozzi Lepri, A, De Luca, A, Gervasoni, C, Girardi, E, Lo Caputo, S, Murri, R, Mussini, C, Puoti, M, Torti, Carlo, Moroni, M, Carosi, Giampiero, Cauda, R, Chiodo, F, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Panebianco, R, Pastore, G, Perno, Cf, Montroni, M, Scalise, G, Costantini, A, Riva, A, Tirelli, U, Martellotta, F, Ladisa, N, Suter, F, Colangeli, V, Fiorini, C, Carosi, G, Cristini, G, Torti, C, Minardi, C, Bertelli, D, Quirino, T, Manconi, Pe, Piano, P, Pizzigallo, E, D'Alessandro, M, Carnevale, G, Zoncada, A, Ghinelli, F, Sighinolfi, L, Leoncini, F, Pozzi, M, Grisorio, B, Ferrara, S, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Soscia, F, Tacconi, L, Orani, A, Perini, P, Tommasi, D, Congedo, P, Chiodera, F, Castelli, P, Rizzardini, G, Caggese, L, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Gori, A, Cagni, S, Abrescia, N, Izzo, Cm, De Marco, M, Viglietti, R, Manzillo, E, Ferrari, C, Pizzaferri, P, Filice, G, Bruno, R, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Andreoni, M, Antonucci, G, Tozzi, V, Acinapura, R, De Longis, P, Trotta, Mp, Lichtner, M, Carletti, F, Mura, Mc, Mannazzu, M, Caramello, P, Orofino, Gc, Sciandra, M, Raise, E, Ebo, F, Pellizzer, G, Buonfrate, D, Caissotti, C, Dellamonica, P, Bentz, L, Bernard, E, De Salvador Guillouet, F, Durant, J, Mondain Miton, V, Perbost, I, Prouvost Keller, B, Pugliese, P, Rahelinirina, V, Roger, Pm, Vandenbos, F, Battegay, M, Bernasconi, E, Böni, J, Bucher, H, Bürgisser, P, Cattacin, S, Cavassini, M, Dubs, R, Egger, M, Elzi, L, Erb, P, Fischer, M, Flepp, M, Fontana, A, Furrer, Hj, Gorgievski, M, Günthard, H, Kaiser, L, Kind, C, Klimkait, T, Lauper, U, Opravil, M, Paccaud, F, Pantaleo, G, Perrin, L, Piffaretti, Jc, Schmid, Cr, Schüpbach, J, Speck, R, Trkola, A, Vernazza, P, and Yerly, S.
- Published
- 2008
37. Changes over time in risk factors for cardiovascular disease and use of lipid-lowering drugs in HIV-infected individuals and impact on myocardial infarction
- Author
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Data Collection on Adverse Events of Anti HIV Drugs Study Group, Sabin, Ca, d'Arminio Monforte, A, Friis Moller, N, Weber, R, El Sadr WM, Reiss, P, Kirk, O, Mercie, P, Law, Mg, De Wit, S, Pradier, C, Phillips, An, Collaborators: Lundgren JD, Lundgren J. D., Collins, S, Loeliger, E, Tressler, R, Weller, I, Friis Møller, N, Worm, Sw, Sjøl, A, Sawitz, A, Rickenbach, M, Pezzotti, P, Krum, E, Gras, L, Balestre, E, Sundström, A, Poll, B, Fontas, E, Torres, F, Petoumenos, K, Kjaer, J, de Wolf, F, Zaheri, S, Bronsveld, W, Hillebrand Haverkort ME, Prins, Jm, Bos, Jc, Eeftinck Schattenkerk JK, Geerlings, Se, Godfried, Mh, Lange, Jm, van Leth FC, Lowe, Sh, van der Meer JT, Nellen, Fj, Pogány, K, van der Poll, T, Ruys, Ta, Sankatsing, S, Steingrover, R, van Twillert, G, van der Valk, M, van Vonderen MG, Vrouenraets, Sm, van Vugt, M, Wit, Fw, van Eeden, A, ten Veen JH, van Dam PS, Roos, Jc, Brinkman, K, Frissen, Ph, Weigel, Hm, Mulder, Jw, van Gorp EC, Meenhorst, Pl, Mairuhu, At, Veenstra, J, Danner, Sa, Van Agtmael MA, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen, M, Richter, C, van der Berg, J, van Leusen, R, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Koger, El, Bravenboer, B, ten Napel CH, Kootstra, Gj, Sprenger, Hg, Miesen, Wm, Doedens, R, Scholvinck, Eh, ten Kate RW, van Houte DP, Polee, M, Kroon, Fp, van den Broek PJ, van Dissel JT, Schippers, Ej, Schreij, G, van de Geest PJ, Verbon, A, Koopmans, Pp, Keuter, M, Post, F, van der Ven AJ, van der Ende ME, Gyssens, Ic, van der Feltz, M, den Hollander JG, de Marie, S, Nouwen, Jl, Rijnders, Bj, de Vries TE, Juttmann, Jr, van de Heul, C, van Kasteren ME, Elisabeth, S, Schneider, Mm, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Hoepelman, Im, Jaspers, Ca, Schouten, I, Schurink, Ca, Blok, Wl, Tanis, Aa, Groeneveld, Ph, Salamon, R, Beylot, J, Dupon, M, Le Bras, M, Pellegrin, Jl, Ragnaud, Jm, Dabis, F, Chêne, G, Jacqmin Gadda, H, Thiébaut, R, Lawson Ayayi, S, Lavignolle, V, Blaizeau, Mj, Decoin, M, Formaggio, Am, Delveaux, S, Labarerre, S, Uwamaliya, B, Vimard, E, Merchadou, L, Palmer, G, Touchard, D, Dutoit, D, Pereira, F, Boulant, B, Morlat, P, Bernard, N, Bonarek, M, Bonnet, F, Coadou, B, Gelie, P, Jaubert, D, Nouts, C, Lacoste, D, Dutronc, H, Cipriano, G, Lafarie, S, Chossat, I, Lacut, Jy, Leng, B, Mercié, P, Viallard, Jf, Faure, I, Rispal, P, Cipriano, C, Tchamgoué, S, Djossou, F, Malvy, D, Pivetaud, Jp, Chambon, D, De La Taille, C, Galperine, T, Neau, D, Ochoa, A, Beylot, C, Doutre, Ms, Bezian, Jh, Moreau, Jf, Taupin, Jl, Conri, C, Constans, J, Couzigou, P, Castera, L, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Trimoulet, P, Moreau, F, Mestre, C, Series, C, Taytard, A, Law, M, Anderson, J, Lowe, K, Mijch, A, Watson, K, Roth, N, Wood, H, Bloch, M, Gowers, A, Baker, D, Mcfarlane, R, Carr, A, Cooper, D, Chuah, J, Fankhauser, W, Mallal, S, Skett, J, Calvo, G, Mateu, S, Domingo, P, Sambeat, Ma, Gatell, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Payen, Mc, Van Laethem, Y, Neaton, J, Thompson, G, Wentworth, D, Luskin Hawk, R, Telzak, E, Abrams, Di, Cohn, D, Markowitz, M, Crane, Lr, Arduino, R, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Sampson, J, Baxter, J, Olsen, Ch, Mocroft, A, Lundgren, Jd, Vetter, N, Karpov, I, Vassilenko, A, Colebunders, R, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Benfield, T, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Zilmer, K, Katlama, C, Viard, Jp, Girard, Pm, Saint Marc, T, Vanhems, P, Dabis, C, Dietrich, M, Manegold, C, van Lunzen, J, Stellbrink, Hj, Staszewski, S, Bieckel, M, Goebel, Fd, Fätkenheuer, G, Rockstroh, J, Schmidt, Re, Kosmidis, J, Gargalianos, P, Sambatakou, H, Perdios, J, Panos, G, Filandras, A, Banhegyi, D, Mulcahy, F, Yust, I, Burke, M, Turner, D, Pollack, S, Hassoun, J, Sthoeger, Z, Maayan, S, Vella, S, Chiesi, A, Arici, C, Pristerá, R, Mazzotta, F, Gabbuti, A, Esposito, R, Bedini, A, Chirianni, A, Montesarchio, E, Vullo, V, Santopadre, P, Narciso, P, Antinori, A, Franci, P, Zaccarelli, M, Lazzarin, A, Castagna, A, D'Arminio Monforte, A, Viksna, L, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Prokopowicz, D, Wiercinska Drapalo, A, Boron Kaczmarska, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Antunes, F, Mansinho, K, Maltez, F, Duiculescu, D, Babes, V, Streinu Cercel, A, Vinogradova, E, Rakhmanova, A, Jevtovic, D, Mokrás, M, Staneková, D, González Lahoz, J, Sanchez Conde, M, García Benayas, T, Martin Carbonero, L, Soriano, V, Clotet, B, Jou, A, Conejero, J, Ruiz, L, Tural, C, Gatell, Jm, Miró, Jm, Zamora, L, Blaxhult, A, Karlsson, A, Pehrson, P, Ledergerber, B, Francioli, P, Telenti, A, Hirschel, B, Soravia Dunand, V, Furrer, H, Kravchenko, E, Chentsova, N, Fisher, M, Brettle, R, Barton, S, Johnson, Am, Mercey, D, Murphy, M, Johnson, Ma, Weber, J, Scullard, G, Morfeldt, L, Thulin, G, Akerlund, B, Koppel, K, Flamholc, L, Håkangård, C, Moroni, M, Cargnel, A, Merli, S, Rizzardini, G, Pastecchia, C, Caggese, L, Moioli, C, Mura, Ms, Mannazzu, M, Suter, F, Manconi, Pe, Piano, P, Lo Caputo, S, Poggiom, A, Bottari, G, Pagano, G, Alessandrini, A, Scasso, A, Vincenti, A, Abbadessa, V, Mancuso, S, Alberici, F, Ruggieri, A, Arlotti, M, Ortolani, P, De Lalla, F, Tositti, G, Cassola, G, Piscopo, R, Raise, E, Ebo, F, Soscia, F, Tacconi, L, Tirelli, U, Di Gennaro, G, Santoro, D, Pusterla, L, Carosi, Giampiero, Torti, Carlo, Cadeo, G, Bertelli, D, Carnevale, G, Galloni, D, Filice, G, Bruno, R, Di Perri, G, Arnaudo, I, Caramello, P, Orofino, Gc, Soranzo, Ml, Bonasso, M, Quirino, T, Melzi, S, Chiodo, F, Colangeli, V, Magnani, G, Ursitti, M, Menichetti, F, Martinelli, C, Mussini, C, Ghinelli, F, Sighinolfi, L, Coronado, O, Ballardini, G, Rizzo, E, Montroni, M, Braschi, Mc, Petrelli, E, Cioppi, A, Cauda, R, De Luca, A, Petrosillo, N, Noto, P, Bontempo, G, Acinapura, A, Antonucci, G, De Longis, P, Lichtner, M, Pastore, G, Ladisa, N, Viglietti, R, Piazza, M, Nappa, S, Abrescia, N, De Marco, M, Colomba, A, Prestileo, T, De Stefano, C, La Gala, A, Cosco, L, Scerbo, A, Grima, P, Tundo, P, Vecchiet, J, D'Alessandro, M, Grisorio, B, Ferrara, S, Caissotti, C, Dellamonica, P, Bentz, L, Bernard, E, De Salvador Guillouet, F, Durant, J, Mondain Miton, V, Perbost, I, Prouvost Keller, B, Pugliese, P, Rahelinirina, V, Roger, Pm, Vandenbos, F, Battegay, M, Bernasconi, E, Böni, J, Bucher, H, Bürgisser, P, Cattacin, S, Cavassini, M, Dubs, R, Egger, M, Elzi, L, Erb, P, Fischer, M, Flepp, M, Fontana, A, Furrer, Hj, Gorgievski, M, Günthard, H, Kaiser, L, Kind, C, Klimkait, T, Lauper, U, Opravil, M, Paccaud, F, Pantaleo, G, Perrin, L, Piffaretti, Jc, Rudin, C, Schmid, P, Schüpbach, J, Speck, R, Trkola, A, Vernazza, P, and Yerly, S.
- Published
- 2008
38. Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study: a multi-cohort collaboration
- Author
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D:A:D Study Group, Sabin, Ca, Worm, Sw, Weber, R, Reiss, P, El Sadr, W, Dabis, F, De Wit, S, Law, M, D'Arminio Monforte, A, Friis Møller, N, Kirk, O, Pradier, C, Weller, I, Phillips, An, Collaborators: Collins S, Lundgren J. D., El Sadr WM, Phillips, A, Rosseau, F, Storfer, Sp, Weber, I, Lundgren, Jd, Sjøl, A, Sawitz, A, Rickenbach, M, Pezzotti, P, Krum, E, Gras, L, Balestre, E, Sundström, A, Poll, B, Fontas, E, Torres, F, Petoumenos, K, Kjaer, J, Hammer, S, Neaton, J, de Wolf, F, Zaheri, S, Bronsveld, W, Hillebrand Haverkort ME, Prins, Jm, Bos, Jc, Eeftinck Schattenkerk JK, Geerlings, Se, Godfried, Mh, Lange, Jm, van Leth FC, Lowe, Sh, van der Meer JT, Nellen, Fj, Pogány, K, van der Poll, T, Ruys, Ta, Sankatsing, Steingrover, R, van Twillert, G, van der Valk, M, van Vonderen MG, Vrouenraets, Sm, van Vugt, M, Wit, Fw, van Eeden, A, ten Veen JH, van Dam PS, Roos, Jc, Brinkman, K, Frissen, Ph, Weigel, Hm, Mulder, Jw, van Gorp EC, Meenhorst, Pl, Mairuhu, At, Veenstra, J, Danner, Sa, Van Agtmael MA, Claessen, Fa, Perenboom, Rm, Rijkeboer, A, van Vonderen, M, Richter, C, van der Berg, J, van Leusen, R, Vriesendorp, R, Jeurissen, Fj, Kauffmann, Rh, Koger, El, Bravenboer, B, ten Napel CH, Kootstra, Gj, Sprenger, Hg, Miesen, Wm, Doedens, R, Scholvinck, Eh, ten Kate RW, van Houte DP, Polee, M, Kroon, Fp, van den Broek, van Dissel JT, Schippers, Ef, Schreij, G, van de Geest, S, Verbon, A, Koopmans, Pp, Keuter, M, Post, F, van der Ven AJ, van der Ende ME, Gyssens, Ic, van der Feltz, M, den Hollander JG, de Marie, S, Nouwen, Jl, Rijnders, Bj, de Vries TE, Juttmann, Jr, van de Heul, C, van Kasteren ME, Elisabeth, St, Schneider, Mm, Bonten, Mj, Borleffs, Jc, Ellerbroek, Pm, Hoepelman, Im, Jaspers, Ca, Schouten, I, Schurink, Ca, Blok, Wl, Tanis, Aa, Groeneveld, Ph, Salamon, R, Beylot, J, Dupon, M, Le Bras, M, Pellegrin, Jl, Ragnaud, Jm, Chêne, G, Jacqmin Gadda, H, Thiébaut, R, Lawson Ayayi, S, Lavignolle, V, Blaizeau, Mj, Decoin, M, Formaggio, Am, Delveaux, S, Labarerre, S, Uwamaliya, B, Vimard, E, Merchadou, L, Palmer, G, Touchard, D, Dutoit, D, Pereira, F, Boulant, B, Morlat, P, Bernard, N, Bonarek, M, Bonnet, F, Coadou, B, Gelie, P, Jaubert, D, Nouts, C, Lacoste, D, Dutronc, H, Cipriano, G, Lafarie, S, Chossat, I, Lacut, Jy, Leng, B, Mercié, P, Viallard, Jf, Faure, I, Rispal, P, Cipriano, C, Tchamgoué, S, Djossou, F, Malvy, D, Pivetaud, Jp, Chambon, D, De La Taille, C, Galperine, T, Neau, D, Ochoa, A, Beylot, C, Doutre, Ms, Bezian, Jh, Moreau, Jf, Taupin, Jl, Conri, C, Constans, J, Couzigou, P, Castera, L, Fleury, H, Lafon, Me, Masquelier, B, Pellegrin, I, Trimoulet, P, Moreau, F, Mestre, C, Series, C, Taytard, A, Anderson, J, Cortossis, P, Hoy, J, Watson, K, Roth, N, Bloch, M, Franic, T, Baker, D, Mcfarlane, R, Carr, A, Cooper, D, Chuah, J, Fankhauser, W, Mallal, S, Forsdyke, C, Calvo, G, Mateu, S, Domingo, P, Sambeat, Ma, Gatel, J, Del Cacho, E, Cadafalch, J, Fuster, M, Codina, C, Sirera, G, Vaqué, A, Clumeck, N, Gerard, M, Kabeya, K, Konopnicki, D, Libois, A, Payen, Mc, Van Laethem, Y, Bartsch, G, Thompson, G, Wentworth, D, Luskin Hawk, R, Telzak, E, Abrams, Di, Cohn, D, Markowitz, N, Arduino, R, Mushatt, D, Friedland, G, Perez, G, Tedaldi, E, Fisher, E, Gordin, F, Crane, Lr, Sampson, J, Baxter, J, Mocroft, A, Vetter, N, Karpov, I, Vassilenko, A, Colebunders, R, Machala, L, Rozsypal, H, Sedlacek, D, Nielsen, J, Benfield, T, Gerstoft, J, Katzenstein, T, Hansen, Ab, Skinhøj, P, Pedersen, C, Zilmer, K, Katlama, C, Viard, Jp, Girard, Pm, Saint Marc, T, Vanhems, P, Dietrich, M, Manegold, C, van Lunzen, J, Stellbrink, Hj, Staszewski, S, Bieckel, M, Goebel, Fd, Fätkenheuer, G, Rockstroh, J, Schmidt, Re, Kosmidis, J, Gargalianos, P, Sambatakou, H, Perdios, J, Panos, G, Filandras, A, Banhegyi, D, Mulcahy, F, Yust, I, Burke, M, Turner, D, Pollack, S, Hassoun, J, Sthoeger, Z, Maayan, S, Vella, S, Chiesi, A, Arici, C, Pristerá, R, Mazzotta, F, Gabbuti, A, Esposito, R, Bedini, A, Chirianni, A, Montesarchio, E, Vullo, V, Santopadre, P, Narciso, P, Antinori, A, Franci, P, Zaccarelli, M, Lazzarin, A, Castagna, A, Viksna, L, Chaplinskas, S, Hemmer, R, Staub, T, Bruun, J, Maeland, A, Ormaasen, V, Knysz, B, Gasiorowski, J, Horban, A, Prokopowicz, D, Wiercinska Drapalo, A, Boron Kaczmarsk, A, Pynka, M, Beniowski, M, Mularska, E, Trocha, H, Antunes, A, Mansinho, K, Maltez, F, Duiculescu, D, Streinu Cercel, A, Vinogradova, E, Rakhmanova, A, Jevtovic, D, Mokrás, M, Staneková, D, González Lahoz, J, Sanchez Conde, M, García Benayas, T, Martin Carbonero, L, Soriano, V, Clotet, B, Jou, A, Conejero, J, Ruiz, L, Tural, C, Gatell, Jm, Miró, Jm, Zamora, L, Gutierrez, M, Mateo, G, Blaxhult, A, Karlsson, A, Pehrson, P, Ledergerber, B, Francioli, P, Telenti, A, Hirschel, B, Soravia Dunand, V, Furrer, H, Kravchenko, E, Chentsova, N, Fisher, M, Brettle, R, Barton, S, Johnson, Am, Mercey, D, Murphy, M, Johnson, Ma, Weber, J, Scullard, G, Morfeld, L, Thulin, G, Akerlund, B, Koppel, K, Flamholc, L, Håkangård, C, d'Arminio Monforte, A, Moroni, M, Cargnel, A, Merli, S, Vigevani, Gm, Pastecchia, C, Morsica, G, Caggese, L, Moioli, C, Mura, Ms, Mannazzu, M, Suter, F, Manconi, Pe, Piano, P, Lo Caputo, S, Poggio, A, Bottari, G, Pagano, G, Alessandrini, A, Scasso, A, Abbadessa, V, Mancuso, S, Alberici, F, Ruggieri, A, Arlotti, M, Ortolani, P, De Lalla, F, Tositti, G, Cassola, G, Piscopo, R, Raise, E, Ebo, F, Soscia, F, Tacconi, L, Tirelli, U, Cinelli, R, Santoro, D, Pusterla, L, Carosi, Giampiero, Torti, Carlo, Cadeo, G, Bertelli, D, Carnevale, G, Citterio, P, Filice, G, Bruno, R, Di Perri, G, Arnaudo, I, Caramello, P, Orofino, Gc, Soranzo, Ml, Bonasso, M, Rizzardini, G, Melzi, S, Chiodo, F, Colangeli, V, Magnani, G, Ursitti, M, Menichetti, F, Martinelli, C, Mussini, C, Ghinelli, F, Sighinolfi, L, Coronado, O, Ballardini, G, Rizzo, E, Montroni, M, Braschi, Mc, Petrelli, E, Cioppi, A, Cauda, R, De Luca, A, Petrosillo, N, Noto, P, Bontempo, G, Acinapura, R, Antonucci, G, De Longis, P, Lichtner, M, Pastore, G, Ladisa, N, Viglietti, R, Piazza, M, Nappa, S, Abrescia, N, De Marco, M, Colomba, A, Prestileo, T, De Stefano, C, La Gala, A, Cosco, L, Scerbo, A, Grima, P, Tundo, P, Vecchiet, J, D'Alessandro, M, Grisorio, B, Ferrara, S, Caissotti, C, Dellamonica, P, Bentz, L, Bernard, E, De Salvador Guillouet, F, Durant, J, Mondain Miton, V, Perbost, I, Prouvost Keller, B, Pugliese, P, Rahelinirina, V, Roger, Pm, Vander, F, Battegay, M, Bernasconi, E, Böni, J, Buche, H, Bürgisser, P, Cattacin, S, Cavassini, M, Dubs, R, Egger, M, Elzi, L, Erb, P, Fischer, M, Flepp, M, Fontana, A, Furrer, Hj, Gorgievski, M, Günthard, H, Kaiser, L, Kind, C, Klimkait, T, Lauper, U, Opravil, M, Paccaud, F, Pantaleo, G, Perrin, L, Piffaretti, Jc, Rudin, C, Schmid, P, Schüpbach, J, Speck, R, Trkola, A, Vernazza, P, and Yerly, S.
- Published
- 2008
39. Recent acquired STD and the use of HAART in the Italian Cohort of Naive for Antiretrovirals (I.Co.N.A): analysis of the incidence of newly acquired hepatitis B infection and syphilis
- Author
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Cicconi, P, Cozzi lepri, A, Orlando, G, Matteelli, A, Girardi, E, Degli Esposti, A, Moioli, C, Rizzardini, G, Chiodera, A, Ballardini, G, Tincati, C, d'Arminio Monforte, A, Collaborators: Montroni M, I. C. o. N. A. Study G. r. o. u. p., Scalise, G, Braschi, Mc, Riva, A, Grima, P, Tirelli, U, Di Gennaro, G, Pastore, G, Ladisa, N, Minafra, G, Suter, F, Arici, C, Chiodo, F, Colangeli, V, Fiorini, C, Coronado, O, Carosi, Giampiero, Cadeo, Gp, Torti, Carlo, Minardi, C, Bertelli, D, Melzi, S, Manconi, Pe, Piano, P, Cosco, L, Scerbo, A, Vecchiet, J, D'Alessandro, M, Santoro, D, Pusterla, L, Carnevale, G, Citterio, P, Viganò, P, Mena, M, Ghinelli, F, Sighinolfi, L, Leoncini, F, Mazzotta, F, Pozzi, M, Lo Caputo, S, Angarano, G, Grisorio, B, Saracino, A, Ferrara, S, Tundo, P, Pagano, G, Cassola, G, Alessandrini, A, Piscopo, R, Toti, M, Chigiotti, S, Soscia, F, Tacconi, L, Orani, A, Perini, P, Scasso, A, Vincenti, A, Castelli, P, Scalzini, A, Palvarini, L, Moroni, M, Lazzarin, A, Cargnel, A, Vigevani, Gm, Caggese, L, Repetto, D, Galli, A, Merli, S, Pastecchia, C, Moioli, Mc, Esposito, R, Mussini, C, Abrescia, N, Chirianni, A, Izzo, Cm, Piazza, M, De Marco, M, Viglietti, R, Manzillo, E, Nappa, S, Colomba, A, Abbadessa, V, Prestileo, T, Mancuso, S, Ferrari, C, Pizzaferri, P, Filice, G, Minoli, L, Bruno, R, Novati, S, Baldelli, F, Tinca, M, Petrelli, E, Cioppi, A, Alberici, F, Ruggieri, A, Menichetti, F, Martinelli, C, De Stefano, C, La Gala, A, Rizzo, E, Magnani, G, Ursitti, Ma, Arlotti, M, Ortolani, P, Cauda, R, Dianzani, F, Ippolito, G, Antinori, A, Antonucci, G, D'Elia, S, Narciso, P, Petrosillo, N, Vullo, V, De Luca, A, Bacarelli, A, Zaccarelli, M, Acinapura, R, De Longis, P, Brandi, A, Trotta, Mp, Noto, P, Lichtner, M, Capobianchi, Mr, Carletti, F, Pezzotti, P, Rezza, G, Mura, Ms, Mannazzu, M, Caramello, P, Di Perri, G, Soranzo, Ml, Orofino, Gc, Arnaudo, I, Bonasso, M, Grossi, Pa, Basilico, C, Poggio, A, Bottari, G, Raise, E, Ebo, F, De Lalla, F, Tositti, G, Resta, F, Loso, K, and Cozzi Lepri, A.
- Published
- 2008
40. Importance of baseline prognostic factors with increasing time since initiation of highly active antiretroviral therapy: collaborative analysis of cohorts of HIV-1-infected patients
- Author
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Sterne, Jonathan A. C., May, Margaret, Sabin, Caroline, Phillips, Andrew, Costagliola, Dominique, Chêne, Geneviève, Justice, Amy C., De Wolf, Frank, Hogg, Robert, Battegay, Manuel, Monforte, Antonella D'Arminio, Gerdtkenheuer, Fa, Staszewski, Schlomo, Gill, John, Egger, Matthias, Casabona, Jordi, Dabis, Francxois, Kitahata, Mari, Leport, Catherine, Lundgren, Jens, Reiss, Peter, Saag, Michael, Weller, Ian, Beckthold, Brenda, Yip, Benita, Dauer, Brenda, Fusco, Jenifer, Lanoy, Emilie, Rickenbach, Martin, Lavignolle, Valerie, Van Sighem, Ard, Pereira, Edwige, Pezzotti, Patrizio, Schmeisser, Norbert, Billaud, E., Boué, F., Costagliola, D., Duval, X., Duvivier, C., Enel, P., Fournier, S., Gasnault, J., Gaud, C., Gilquin, J., Grabar, S., Khuong, M. A., Lang, J. M., Mary Krause, M., Matheron, S., Meyohas, M. C., Pialoux, G., Poizot Martin, I., Pradier, C., Rouveix, E., Salmon Ceron, D., Sobel, A., Tattevin, P., Tissot Dupont, H., Yasdanpanah, Y., Aronica, E, Tirard Fleury, V., Tortay, I., Abgrall, S., Guiguet, M., Lanoy, E., Leneman, H., Lièvre, L., Potard, V., Saidi, S., Vildé, J. L., Leport, C., Yeni, P., Bouvet, E., Gaudebout, C., Crickx, B., Picard Dahan, C., Weiss, L., Tisne Dessus, D., Sicard, D., Salmon, D., Auperin, I., Viard, J. P., Roudière, L., Fior, R., Delfraissy, J. F., Goujard, C., Lesprit, P. h., Jung, C., Meynard, J. L., Picard, O., Desplanque, N., Cadranel, J., Mayaud, C., Rozenbaum, W., Bricaire, F., Katlama, C., Herson, S., Simon, A., Decazes, J. M., Molina, J. M., Clauvel, J. P., Gerard, L., Sellier, P., Diemer, M., Dupont, C., Berthé, H., Saïag, P., Mortier, E., Chandemerle, C., De Truchis, P., Bentata, M., Honoré, P., Tassi, S., Jeantils, V., Mechali, D., Taverne, B., Laurichesse, H., Gourdon, F., Lucht, F., Fresard, A., Faller, J. P., Eglinger, P., Bazin, C., Verdon, R., Peyramond, D., Boibieux, A., Touraine, J. L., Livrozet, J. M., Trepo, C., Cotte, L., Ravaux, I., Delmont, J. P., Moreau, J., Gastaut, J. A., Soubeyrand, J., Retornaz, F., Blanc, P. A., Allegre, T., Galinier, A., Ruiz, J. M., Lepeu, G., Granet Brunello, P., Pelissier, L., Esterni, J. P., Nezri, M., Cohen Valensi, R., Laffeuillade, A., Chadapaud, S., Reynes, J., May, T., Rabaud, C., Raffi, F., Pugliese, P., Michelet, C., Arvieux, C., Caron, F., Borsa Lebas, F., Rey, D., Fraisse, P., Massip, P., Cuzin, L., Arlet Suau, E., Thiercelin Legrand, M. F., Sobesky, M., Pradinaud, R., Contant, M., Montroni, M., Scalise, G., Braschi, M. C., Riva, A., Tirelli, U., Cinelli, R., Pastore, G., Ladisa, N., Minafra, G., Suter, F., Arici, C., Pristera, R., Chiodo, F., Colangeli, V., Fiorini, C., Coronado, O., Carosi, G., Cadeo, G. P., Torti, C., Minardi, C., Bertelli, D., Rizzardini, G., Melzi, S., Manconi, P. E., Piano, P., Cosco, L., Scerbo, A., Vecchiet, J., D'Alessandro, M., Santoro, D., Pusterla, L., Carnevale, G., Citterio, P., Viganò, P., Mena, M., Ghinelli, F., Sighinolfi, L., Leoncini, F., Mazzotta, F., Pozzi, M., Lo Caputo, S., Vullo, Vincenzo, Lichtner, Miriam, Angarano, G., Grisorio, B., Saracino, A., Ferrara, S., Grima, P., Tundo, P., Pagano, G., Cassola, G., Alessandrini, A., Piscopo, R., Toti, M., Chigiotti, S., Soscia, F., Tacconi, L., Orani, A., Perini, P., Scasso, A., Vincenti, A., Chiodera, F., Castelli, P., Scalzini, A., Palvarini, L., Moroni, M., Lazzarin, A., Cargnel, A., Vigevani, G. M., Caggese, L., d'Arminio Monforte, A., Repetto, D., Galli, A., Merli, S., Pastecchia, C., Moioli, M. C., Esposito, R., Mussini, C., Abrescia, N., Chirianni, A., Izzo, C. M., Piazza, M., De Marco, M., Viglietti, R., Manzillo, E., Nappa, S., Antonucci, G., Iacomi, F., Narciso, P., Zaccarelli, M., Colomba, A., Abbadessa, V., Prestileo, T., Mancuso, S., Ferrari, C., Pizzaferri, P., Filice, G., Minoli, L., Bruno, R., Novati, S., Baldelli, F., Tinca, M., Petrelli, E., Cioppi, A., Alberici, F., Ruggieri, A., Menichetti, F., Martinelli, C., De Stefano, C., La Gala, A., Ballardini, G., Rizzo, E., Magnani, G., Ursitti, M. A., Arlotti, M., Ortolani, P., Cauda, R., Dianzani, F., Ippolito, G., Antinori, A., D'Elia, S., Petrosillo, N., De Luca, A., Bacarelli, A., Acinapura, R., De Longis, P., Brandi, A., Trotta, M. P., Noto, P., Capobianchi, M. R., Carletti, F., Girardi, E., Pezzotti, P., Rezza, G., Mura, M. S., Mannazzu, M., Caramello, P., Di Perri, G., Soranzo, M. L., Orofino, G. C., Arnaudo, I., Bonasso, M., Grossi, P. A., Basilico, C., Poggio, A., Bottari, G., Raise, E., Ebo, F., De Lalla, F., Tositti, G., Resta, F., Loso, K., Cozzi Lepri, A., Johnson, A. M., Mercey, D., Phillips, A., Johnson, M. A., Mocroft, A., Murphy, M., Weber, J., Scullard, G., Fisher, M., Battegay, M., Bernasconi, E., Böni, J., Bucher, H., Bürgisser, P. h., Cattacin, S., Cavassini, M., Dubs, R., Egger, M., Elzi, L., Erb, P., Fantelli, K., Fischer, M., Flepp, M., Fontana, A., Francioli, P., Hirschel, B., Soravia Dunand, V., Furrer, H., Gorgievski, M., Günthard, H., Kaiser, L., Kind, C., Klimkait, T. h., Lauper, U., Ledergerber, B., Opravil, M., Paccaud, F., Pantaleo, G., Perrin, L., Piffaretti, J. C., Rickenbach, M., Rudin, C., Schmid, P., Schüpbach, J., Speck, R., Telenti, A., Trkola, A., Vernazza, P., Buy, E., Bronsveld, W., Hillebrand Haverkort, M. E., Reiss, P., Back, N. K. T., Bakker, M. E. G., Berkhout, B., Jurriaans, S., Cuijpers, T. h., Rietra, P. J. G. M., Roozendaal, K. J., Pauw, W., Van Zanten, A. P., Smits, P. H. M., Von Blomberg, B. M. E., Savelkoul, P., Danner, S. A., Van Agtmael, M. A., Claessen, F. A. P., Perenboom, R. M., Rijkeboer, A., Van Vonderen, M., Kuijpers, T. W., Pajkrt, D., Scherpbier, H. J., Prins, J. M., Bos, J. C., Eeftinck Schattenkerk, J. K. M., Geerlings, S. E., Godfried, M. H., Lange, J. M. A., Van Leth, F. C., Lowe, S. H., Van Der Meer, J. T. M., Nellen, F. J. B., Pogány, K., Van Der Poll, T., Ruys, T. h. A., Sankatsing, S., Steingrover, R., Van Twillert, G., Van Der Valk, M., Van Vonderen, M. G. A., Vrouenraets, S. M. E., Van Vugt, M., Wit, F. W. M. N., Veenstra, J., Van Eeden, A., Veen, J. H., Van Dam, P. S., Roos, J. C., Brinkman, K., Frissen, P. H. J., Weigel, H. M., Mulder, J. W., Van Gorp, E. C. M., Meenhorst, P. L., Mairuhu, A. T. A., Richter, C., Van Der Berg, J., Van Leusen, R., Swanink, C. M. A., Vriesendorp, R., Jeurissen, F. J. F., Franck, P. F. H., Lampe, A. S., Kauffmann, R. H., Koger, E. L. W., Bravenboer, B., Ten Napel, C. H. H., Kootstra, G. J., Schirm, J., Bennw, C. A., Sprenger, H. G., Miesen, W. M. A. J., Doedens, R., Scholvinck, E. H., Ten Kate, R. W., Van Houte, D. P. F., Polee, M., Kroes, A. C. M., Claas, H. C. J., Kroon, F. P., Van Den, Broek, Van Dissel, J. T., Schippers, E. F., Bruggeman, C. A. M. V. A., Goossens, V. J., Schreij, G., Van De Geest, S., Verbon, A., Galama, J. M. D., Melchers, W. J. G., Poort, Y. A. G., Koopmans, P. P., Keuter, M., Post, F., Van Der Ven, A. J. A. M., Doornum, G. J. J., Niesters, M. G., Osterhaus, A. D. M. E., Schutten, M., Driessen, G., De Groot, R., Hartwig, N., Van Der Ende, M. E., Gyssens, I. C., Van Der Feltz, M., Den Hollander, J. G., De Marie, S., L. Nouwen, J., Rijnders, B. J. A., De Vries, T. E. M. S., Juttmann, J. R., Van De Heul, C., Van Kasteren, M. E. E., Boucher, C. A. B., Schuurman, R., Geelen, S. P. M., Wolfs, T. F. W., Schneider, M. M. E., Bonten, M. J. M., Borleffs, J. C. C., Ellerbroek, P. M., Hoepelman, I. M., Jaspers, C. A. J. J., Schouten, I., Schurink, C. A. M., Blok, W. L., Tanis, A. A., Groeneveld, P. H. P., Jansen, C. L., Hendriks, R., Veenendaal, D., Storm, H., Weel, J., Van Zeijl, J. H., Buiting, A. G. M., Swaans, C. A. M., Boel, E., Jansz, A. F., Losso, M., Duran, A., Vetter, N., Karpov, I., Vassilenko, A., Clumeck, N., Dewit, S., Poll, B., Colebunders, R., Machala, L., Rozsypal, H., Sedlacek, D., Gerstoft, J., Katzenstein, T., Hansen, A. B. E., Skinhøj, P., Nielsen, J., Lundgren, J., Benfield, T., Kirk, O., Pedersen, C., Zilmer, K., Girard, P. M., Saint Marc, T., Vanhems, P., Dabis, F., Dietrich, M., Manegold, C., Van Lunzen, J., Stellbrink, H. J., Staszewski, S., Bickel, M., Goebel, F. D., Fätkenheuer, G., Rockstroh, J., Schmidt, R., Kosmidis, J., Gargalianos, P., Sambatakou, H., Perdios, J., Panos, G., Filandras, A., Karabatsaki, E., Banhegyi, D., Mulcahy, F., Yust, I., Turner, D., Burke, M., Pollack, S., Hassoun, G., Sthoeger, Z., Maayan, S., Borghi, R., Cotugno, A. D., Gabbuti, A., Chiesi, A., Montesarchio, E., Finazzi, R., D'Arminio Monforte, A., Viksna, L., Chaplinskas, S., Hemmer, R., Staub, T., Bruun, J., Maeland, A., Ormaasen, V., Knysz, B., Gasiorowski, J., Horban, A., Prokopowicz, D., Wiercinska Drapalo, A., Boron Kaczmarska, A., Pynka, M., Beniowski, M., Mularska, E., Trocha, H., Antunes, F., Valadas, E., Mansinho, K., Matez, F., Duiculescu, D., Babes, Victor, Streinu Cercel, A., Vinogradova, E., Rakhmanova, A., Jevtovic, D., Mokráš, M., Staneková, D., González Lahoz, J., Sánchez Conde, M., García Benayas, T., Martin Carbonero, L., Soriano, V., Clotet, B., Jou, A., Conejero, J., Tural, C., Gatell, J. M., Miró, J. M., Blaxhult, A., Karlsson, A., Pehrson, P., Weber, R., Kravchenko, E., Chentsova, N., Barton, S., Brettle, R., Loveday, C., Antunes, Francisco, Blaxhult, Anders, Clumeck, Nathan, Gatell, Jose, Horban, Andrzej, Johnson, Anne, Katlama, Christine, Ledergerber, Bruno, Loveday, Clive, Vella, Stefano, Gjørup, I., Friis Moeller, N., Bannister, W., Mollerup, D., Podlevkareva, D., Holkmann Olsen, C., Kjær, J., Raffanti, Stephen, Dieterch, Douglas, Becker, Stephen, Scarsella, Anthony, Fusco, Gregory, Most, Bernard, Balu, Rukmini, Rana, Rashida, Beckerman, Robin, Ising, Theodore, Fusco, Jennifer, Irek, Renae, Johnson, Bernadette, Hirani, Ashwin, Edwinjesus, De, Pierone, Gerald, Lackey, Philip, Irek, Chip, Johnson, Alison, Burdick, John, Leon, Saul, Arch, Joseph, Helm, Eilke B., Carlebach, Amina, Axelller, Mu, Haberl, Annette, Nisius, Gabi, Lennemann, Tessa, Rottmann, Carsten, Wolf, Timo, Stephan, Christoph, Bickel, Markus, Manfredsch, Mo, Gute, Peter, Locher, Leo, Lutz, Thomas, Klauke, Stephan, Knecht, Gabi, Doerr, Hans W., Stu, Martinrmer, Von Hentig, Nils, Jennings, Beverly, Beylot, J., Chêne, G., Dupon, M., Longy Boursier, M., Pellegrin, J. L., Ragnaud, J. M., Salamon, R., Thiébaut, R., Lewden, C., Lawson Ayayi, S., Mercié, P., Moreau, J. F., Morlat, P., Bernard, N., Lacoste, D., Malvy, D., Neau, D., Blaizeau, M. J., Decoin, M., Delveaux, S., Hannapier, C., Labarrère, S., Lavignolle Aurillac, V., Uwamaliya Nziyumvira, B., Palmer, G., Touchard, D., Balestre, E., Alioum, A., Jacqmin Gadda, H., Bonarek, M., Bonnet, F., Coadou, B., Gellie, P., Nouts, C., Bocquentin, F., Dutronc, H., Lafarie, S., Aslan, A., Pistonne, T., Thibaut, P., Vatan, R., Chambon, D., De La Taille, C., Cazorla, C., Ocho, A., Viallard, J. F., Caubet, O., Cipriano, C., Lazaro, E., Couzigou, P., Castera, L., Fleury, H., Lafon, M. E., Masquelier, B., Pellegrin, I., Breilh, D., Blanco, P., Loste, P., Caunègre, L., Bonnal, F., Farbos, S., Ferrand, M., Ceccaldi, J., Tchamgoué, S., De Witte, S., Alexander, Chris, Barrios, Rolando, Braitstein, Paula, Brumme, Zabrina, Chan, Keith, Cote, Helen, Gataric, Nada, Geller, Josie, Guillemi, Silvia, Richard Harrigan, P., Harris, Marrianne, Joy, Ruth, Levy, Adrian, Montaner, Julio, Montessori, Val, Palepu, Anita, Phillips, Elizabeth, Phillips, Peter, Press, Natasha, Tyndall, Mark, Wood, Evan, Bhagani, S., Byrne, P., Carroll, A., Cuthbertson, Z., Dunleavy, A., Geretti, A. M., Heelan, B., Johnson, M., Kinloch de Loes, S., Lipman, M., Madge, S., Marshall, N., Nair, D., Nebbia, G., Prinz, B., Swaden, L., Tyrer, M., Youle, M., Chaloner, C., Grabowska, H., Holloway, J., Puradiredja, J., Ransom, D., Tsintas, R., Bansi, L., Fox, Z., Harris, E., Hill, T., Lampe, F., Lodwick, R., Reekie, J., Sabin, C., Smith, C., Amoah, E., Booth, C., Clewley, G., Garcia Diaz, A., Gregory, B., Labbett, W., Tahami, F., Thomas, M., Read, Ron, Fatkenheuer, G., Schmeisser, N., Voigt, K., Wasmuth, J. C., Wohrmann, A., Infectious diseases, AII - Amsterdam institute for Infection and Immunity, APH - Amsterdam Public Health, Medical Microbiology and Infection Prevention, Paediatric Infectious Diseases / Rheumatology / Immunology, Landsteiner Laboratory, ARD - Amsterdam Reproduction and Development, Graduate School, Cardiology, APH - Global Health, APH - Quality of Care, AII - Infectious diseases, AII - Inflammatory diseases, and Global Health
- Subjects
Adult ,medicine.medical_specialty ,AIDS ,CD4 counts ,Highly active antiretroviral therapy ,HIV ,Prognosis ,Substance abuse (intravenous) ,Adolescent ,Anti-HIV Agents ,Antiretroviral Therapy, Highly Active ,CD4 Lymphocyte Count ,Europe ,HIV Infections ,HIV-1 ,Humans ,Middle Aged ,North America ,Risk Factors ,Substance Abuse, Intravenous ,Survival Analysis ,Pharmacology (medical) ,Infectious Diseases ,Cost effectiveness ,Antiretroviral Therapy ,Article ,Acquired immunodeficiency syndrome (AIDS) ,Internal medicine ,medicine ,Highly Active ,Survival analysis ,Immunodeficiency ,business.industry ,Transmission (medicine) ,Hazard ratio ,Substance Abuse ,medicine.disease ,Confidence interval ,Physical therapy ,Intravenous ,business ,Cohort study - Abstract
Background: The extent to which the prognosis for AIDS and death of patients initiating highly active antiretroviral therapy (HAART) continues to be affected by their characteristics at the time of initiation (baseline) is unclear. Methods: We analyzed data on 20,379 treatment-naive HIV-1- infected adults who started HAART in 1 of 12 cohort studies in Europe and North America (61,798 person-years of follow-up, 1844 AIDS events, and 1005 deaths). Results: Although baseline CD4 cell count became less prognostic with time, individuals with a baseline CD4 count 350 cells/μL (hazard ratio for AIDS = 2.3, 95% confidence interval [CI]: 1.0 to 2.3; mortality hazard ratio = 2.5, 95% CI: 1.2 to 5.5, 4 to 6 years after starting HAART). Rates of AIDS were persistently higher in individuals who had experienced an AIDS event before starting HAART. Individuals with presumed transmission by means of injection drug use experienced substantially higher rates of AIDS and death than other individuals throughout follow-up (AIDS hazard ratio = 1.6, 95% CI: 0.8 to 3.0; mortality hazard ratio = 3.5, 95% CI: 2.2 to 5.5, 4 to 6 years after starting HAART). Conclusions: Compared with other patient groups, injection drug users and patients with advanced immunodeficiency at baseline experience substantially increased rates of AIDS and death up to 6 years after starting HAART.
- Published
- 2007
41. A comparison between abacavir and efavirenz as the third drug used in combination with a background therapy regimen of 2 nucleoside reverse-transcriptase inhibitors in patients with initially suppressed viral loads
- Author
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Cozzi Lepri, A, De Luca, A, Phillips, An, Bongiovanni, M, Di Giambenedetto, S, Mena, M, Moioli, Mc, Arlotti, M, Sighinolfi, L, Narciso, P, Lichtner, M, Cauda, R, Monforte, A, Montroni, M., Scalise, G., Braschi, M. C., Riva, A., Tirelli, U., Di Gennaro, G., G. Pastore, N. Ladisa, Minafra, G., Suter, F., Arici, C., Chiodo, F., Colangeli, V., Fiorini, C., Coronado, O., Carosi, G., Cadeo, G. P., Torti, Carlo, Minardi, C., Bertelli, D., Rizzardini, G., Melzi, S., Manconi, P. E., Piano, P., Cosco, L., Scerbo, A., Vecchiet, J., D’Alessandro, M., Santoro, D., Pusterla, L., Carnevale, G., Citterio, P., Viganò, P., Ghinelli, F., Leoncini, F., Mazzotta, F., Pozzi, M., Lo Caputo, S., Angarano, G., Grisorio, B., Saracino, A., Ferrara, S., Grima, P., Tundo, P., Pagano, G., Cassola, G., Alessandrini, A., Piscopo, R., Toti, M., Chigiotti, S., Soscia, F., Tacconi, L., Orani, A., Perini, P., Scasso, A., Vincenti, A., Chiodera, F., Castelli, P., Scalzini, A., Palvarini, L., Moroni, M., Lazzarin, A., Cargnel, A., Vigevani, G. M., Caggese, L., Repetto, D., Galli, A., Merli, S., Pastecchia, C., Molioli, M. C., Esposito, R., Mussini, C., Abrescia, N., Chirianni, A., Izzo, C. M., Piazza, M., De Marco, M., Viglietti, R., Manzillo, E., Nappa, S., Colomba, A., Abbadessa, V., Prestileo, T., Mancuso, S., Ferrari, C., Pizzaferri, P., Filice, G., Minoli, L., Bruno, R., Novati, S., Baldelli, F., Tinca, M., Petrelli, E., Cioppi, A., Alberici, F., Ruggieri, A., Menichetti, F., Martinelli, C., De Stefano, C., La Gala, A., Ballardini, G., Rizzo, E., Magnani, G., Ursitti, M. A., Ortolani, P., Dianzani, F., Ippolito, G., Antinori, A., Antonucci, G., Ciardi, M., Petrosillo, N., Vullo, V., Bacarelli, A., Zaccarelli, M., Acinapura, R., De Longis, P., Brandi, A., Trotta, M. P., Noto, P., Capobianchi, M. R., Carletti, F., Girardi, E., Pezzotti, P., Rezza, G., Mura, M. S., Mannazzu, M., Caramello, P., Di Perri, G., Soranzo, M. L., Orofino, G. C., Arnaudo, I., Bonasso, M., Grossi, P. A., Basilico, C., Poggio, A., Bottari, G., Raise, E., Ebo, F., De Lalla, F., Tositti, G., Resta, F., Loso, K., Ammassari, A., A. C. i. n. g. o. l. a. n. i., . S., Fantoni, Marasca, G., Tamburrini, E., Visconti, E., Bini, A. T., Cicconi, P., Tordato, F., Formenti, T., and Zini, G.
- Published
- 2006
42. Linee guida per la diagnosi e terapia dell'Immunodeficienza Comune Variabile (ICV)
- Author
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Aiuti, F, Aiuti, A, Calza, L, Chiodo, F, DE SANTIS, W, D'Ettorre, G, Emmi, L, Isgro', A, Luzi, Giuseppe, Maggi, E, Marziali, M, Mezzaroma, I, Montroni, M, Muscaritoli, Maurizio, Paganelli, R, Pandolfi, F, Starnino, S, Sirianni, Mc, Spadaro, G, and Vullo, V.
- Published
- 2006
43. Italian Society Of Allergy And Clinical Immunology Guidelines For The Diagnosis And Treatment Of Common Variable Immunodeficiency (Cvid)
- Author
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Aiuti, Fernando, Aiuti, A., Calza, L., Chiodo, F., DE SANTIS, W., Dettorre, G., Emmi, L., Isgro', A., Luzi, Giuseppe, Maggi, E., Marziali, M., Mezzaroma, Ivano, Montroni, M., Muscaritoli, Maurizio, Paganelli, R., Pandolfi, F., Starnino, S., Sirianni, Maria Caterina, and Vullo, Vincenzo
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Diagnosis ,Immunodeficiency ,Immunoglobulins ,Therapy ,Guidelines - Published
- 2006
44. Interruption of highly active antiretroviral therapy in HIV clinical practice: Results from the Italian cohort of antiretroviral-naive patients
- Author
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D'ARMINIO MONFORTE, A, COZZI LEPRI, A, Phillips, A, DE LUCA, A, Murri, R, Mussini, C, Grossi, PAOLO ANTONIO, Galli, A, Zauli, T, Montroni, M, Tundo, P, Moroni, M, ITALIAN COHORT OF, and ANTIRETROVIRAL NAIVE PATIENTS STUDY GROUP
- Subjects
Adult ,Male ,medicine.medical_specialty ,HAART ,Time Factors ,Clinical progression ,HIV Infections ,Treatment interruption ,Drug Administration Schedule ,law.invention ,HIV ,AIDS ,Highly active antiretroviral therapy ,Acquired immunodeficiency syndrome (AIDS) ,Randomized controlled trial ,law ,Interquartile range ,Internal medicine ,Antiretroviral Therapy, Highly Active ,medicine ,Humans ,Pharmacology (medical) ,Probability ,business.industry ,Medicine (all) ,Viral Load ,medicine.disease ,Confidence interval ,Discontinuation ,Surgery ,CD4 Lymphocyte Count ,Clinical setting ,Regimen ,Infectious Diseases ,Treatment Outcome ,Italy ,Cohort ,Female ,business ,Viral load ,Sexuality ,Follow-Up Studies - Abstract
OBJECTIVES: To investigate the frequency of a first therapy interruption (TI) > or = 12 weeks, to identify the factors associated with TI and with therapy resumption, and to compare the risk of developing clinical events during TI and during continuous therapy. METHODS: Observational study of 3142 patients who started a first highly active antiretroviral therapy (HAART) regimen. End points were time to (1) first TI of > or = 12 weeks, (2) subsequent therapy resumption, and (3) development of new AIDS-related events or death. RESULTS: Over a median follow-up period of 41 months (interquartile range: 18-60 months), 721 patients (22.9%) interrupted HAART for > or = 12 weeks, with a probability of 28.6% (95% confidence interval [CI]: 26.7-30.6) by 4 years from the date of therapy initiation. Patient decision (47.4%) and toxicity (24.0%) were the main reasons for TI. Women, injection drug users, and patients with a higher current CD4 cell count were more likely to interrupt. The median time to therapy resumption was 12 months (95% CI: 11-14). The higher the current CD4 count, the slower was the rate of resuming therapy; conversely, patients who stopped because of failure and those with a pre-HAART viral load >100,000 copies/mL resumed therapy sooner. Two hundred eighty-one patients experienced clinical progression at a rate of 2.6 per 100 person-years (pys) (95% CI: 2.3-3.0) while patients were on therapy and 3.5 per 100 pys (95% CI: 2.4-4.8) during TI. The adjusted relative hazard of clinical progression associated with TI was 2.75 (95% CI: 1.14-6.65; P = 0.03). CONCLUSIONS: TI occurring in clinical practice is associated with an increased risk of clinical progression; hence, it should be discouraged outside strictly experimental settings.
- Published
- 2005
45. Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals
- Author
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Paiardini, M, Cervasi, B, Albrecht, H, Muthukumar, A, Dunham, R, Gordon, S, Radziewicz, H, Piedimonte, Giuseppe, Magnani, M, Montroni, M, Kaech, Sm, Weintrob, A, Altman, Jd, Sodora, Dl, Feinberg, Mb, and Silvestri, G.
- Published
- 2005
46. Economic evaluation of HIV treatments: The I.CO.N.A. cohort study
- Author
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Merito, Monica, Bonaccorsi, Andrea, Pammolli, Fabio, Riccaboni, Massimo, Baio, Gianluca, Arici, Claudio, D'Arminio Monforte, Antonella, Pezzotti, Patrizio, Corsini, Dario, Tramarin, Andrea, Cauda, Roberto, Colangeli, Vincenzo, Pastore, Giuseppe, Montroni, M., Scalise, G., Braschi, M. C., Del Prete, M. S., Tirelli, U., Cinelli, R., Ladisa, N., Minafra, G., Suter, F., Chiodo, F., Fiorini, C., Coronado, O., Carosi, G., Cadeo, G. P., Torti, C., Minardi, C., Bertelli, D., Rizzardini, G., Migliorino, G., Manconi, P. E., Piano, P., Ferraro, T., Scerbo, A., Pizzigallo, E., D'Alessandro, M., Santoro, D., Pusterla, L., Carnevale, G., Galloni, D., Viganò, P., Mena, M., Ghinelli, F., Sighinolfi, L., Leoncini, F., Mazzotta, F., Pozzi, M., Lo Caputo, S., Angarano, G., Grisorio, B., Saracino, A., Ferrara, S., Grima, P., Tundo, P., Pagano, G., Cassola, G., Alessandrini, A., Piscopo, R., Toti, M., Chigiotti, S., Soscia, F., Tacconi, L., Orani, A., Perini, P., Scasso, A., Vincenti, A., Chiodera, F., Castelli, P., Scalzini, A., Fibbia, G., Moroni, M., Lazzarin, A., Cargnel, A., Vigevani, G. M., Caggese, L., Repetto, D., Novati, R., Galli, A., Merli, S., Pastecchia, C., Moioli, M. C., Esposito, R., Mussini, C., Abrescia, N., Chirianni, A., Izzo, C. M., Piazza, M., De Marco, M., Viglietti, R., Manzillo, E., Graf, M., Colomba, A., Abbadessa, V., Prestileo, T., Mancuso, S., Ferrari, C., Pizzaferri, P., Filice, G., Minoli, L., Bruno, R., Novati, S., Baldelli, F., Tinca, M., Petrelli, E., Cioppi, A., Alberici, F., Ruggieri, A., Menichetti, F., Martinelli, C., De Stefano, C., La Gala, A., Ballardini, G., Briganti, E., Magnani, G., Ursitti, M. A., Arlotti, M., Ortolani, P., Dianzani, F., Ippolito, G., Antinori, A., Antonucci, G., D'Elia, S., Narciso, P., Petrosillo, N., Vullo, Vincenzo, De Luca, A., Di Giambenedetti, S., Zaccarelli, M., Acinapura, R., De Longis, P., Ciardi, Maria Rosa, D'Offizi, G., Trotta, M. P., Noto, P., Lichtner, Miriam, Capobianchi, M. R., Girardi, E., Rezza, G., Mura, M. S., Mannazzu, M., Resta, F., Loso, K., Caramello, P., Sinicco, A., Soranzo, M. L., Orofino, G., Sciandra, M., Bonasso, M., Grossi, P. A., Basilico, C., Poggio, A., Bottari, G., Raise, E., Pasquinucci, S., De Lalla, F., Tositti, G., and Lepri, A. Cozzi
- Subjects
Pediatrics ,medicine.medical_specialty ,HAART ,Settore MED/17 - Malattie Infettive ,National Health Programs ,Costs per person-year ,Health resources ,HIV infection ,Antiretroviral Therapy, Highly Active ,Cohort Studies ,Costs and Cost Analysis ,HIV Infections ,Health Care Costs ,Humans ,Italy ,Health Policy ,Antiretroviral Therapy ,Indirect costs ,Acquired immunodeficiency syndrome (AIDS) ,medicine ,Highly Active ,Seroconversion ,Health policy ,health care economics and organizations ,business.industry ,Medicine (all) ,medicine.disease ,Antiretroviral therapy ,Cohort ,Economic evaluation ,business ,Cohort study - Abstract
Objective: To describe the changes in costs of care for HIV-positive patients in Italy after the spread of antiretroviral combination therapies (HAART).Methods: Five thousand four hundred and twenty-two patients from the I.CO.N.A. (Italian Cohort Naive Antiretrovirals) study were followed between 1997 and 2002. Costs included antiretroviral therapies (ART), hospital admissions, prophylaxis, and main laboratory examinations. The perspective was that of the National Health Service.Results: Admission costs per person-year decreased from 2148 euro in 1997 to 256 in 2002, while the average annual costs of ART increased from 2145 to 3149 euro (1997 prices). From 1997 to]999, ART costs increased from 42.3 to 85.9% of the total, while admission costs decreased from 42.3 to 7.0% and prophylaxis from 7.3 to 1.7%. The breakdown of ART costs shows how dual therapies decreased over time in favor of HAART, falling from 26.8% in 1997 to 5.9% in 2002. Patients with fewer than five treatment switches had the lowest costs distributions over the entire observation period.Conclusions: From 1997 to 2002 inpatient costs progressively decreased in favor of antiretroviral therapy. Annual average costs per patient decreased, while total direct costs increased over time: health resources, initially concentrated on hospitalized patients were then distributed over a growing number of subjects. (c) 2005 Elsevier Ireland Ltd. All rights reserved.
- Published
- 2005
47. Impact of highly active antiretroviral therapy on the presenting features and outcome of patients with acquired immunodeficiency syndrome-related Kaposi sarcoma
- Author
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Nasti, G, Martellotta, F, Berretta, M, Mena, M, Fasan, M, DI PERRI, Giovanni, Talamini, R, Pagano, G, Montroni, M, Cinelli, R, Vaccher, E, D'ARMINIO MONFORTE, A, Tirelli, U, and Gicat, Icona
- Subjects
Adult ,Male ,Cancer Research ,medicine.medical_specialty ,Settore MED/17 - Malattie Infettive ,Natural history ,Cohort Studies ,Highly active antiretroviral therapy ,Acquired immunodeficiency syndrome (AIDS) ,Internal medicine ,Immunopathology ,Antiretroviral Therapy, Highly Active ,medicine ,Humans ,Neoplasm Invasiveness ,Neoplasm Metastasis ,Sida ,Sarcoma, Kaposi ,Aged ,Retrospective Studies ,Acquired Immunodeficiency Syndrome ,biology ,business.industry ,Cancer ,Kaposi sarcoma ,Retrospective cohort study ,Middle Aged ,medicine.disease ,biology.organism_classification ,Prognosis ,Survival Analysis ,Surgery ,Treatment Outcome ,Oncology ,Acquired immunodeficiency syndrome ,Female ,Sarcoma ,business ,Complication - Abstract
BACKGROUND The objective of the current study was to evaluate the impact of highly active antiretroviral therapy (HAART) on clinical characteristics of presentation and the natural history of Kaposi sarcoma (KS) in patients already receiving HAART at the time of KS diagnosis. METHODS The authors conducted a retrospective cohort study comparing epidemiologic, clinical, and outcome data for 160 patients who were naive to HAART at the time of KS diagnosis (KS-naive) with the corresponding data for 51 patients already receiving HAART at the time of KS diagnosis (KS-HAART). The analysis included all patients with a diagnosis of KS since January 1996 within two Italian cohorts of patients with human immunodeficiency virus. RESULTS Immunologic and virologic status at the time of KS diagnosis were significantly more favorable in the KS-HAART group than in the KS-naive group. The frequency of cutaneous involvement was similar in both groups, but cutaneous disease was more indolent among KS-HAART patients, with 1 anatomic site of involvement in 9 patients (21%) and less than 10 lesions in 26 patients (60%), compared with 16 patients (12%; P = 0.06) and 47 patients (34%; P = 0.01), respectively, in the KS-naive group. A smaller proportion of KS-HAART patients presented with visceral disease (24% vs. 39%; P = 0.06); in particular, gastrointestinal tract involvement was significantly less frequent among KS-HAART patients (14%) compared with KS-naive patients (28%; P = 0.05). Median survival was not reached in either group, and the 3-year survival rates of KS-HAART patients (64%) and KS-naive patients (78%) were not significantly different. CONCLUSIONS The data from the current study indicate that KS exhibits a less aggressive presentation in patients already receiving HAART compared with patients who are naive to HAART at KS diagnosis. Natural history and outcome do not appear to be influenced by the initiation of HAART before development of KS. Cancer 2003. © 2003 American Cancer Society.
- Published
- 2003
48. Virologic and immunologic response to regimens containing nevirapine or efavirenz in combination with 2 nucleoside analogues in the Italian Cohort Naive Antiretrovirals (I.Co.N.A.) study
- Author
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Cozzi-Lepri, Alessandro, Phillips, Andrew N., D'Arminio Monforte, Antonella, Piersantelli, Nicoloò, Orani, Anna, Petrosillo, Nicola, Leoncini, Francesco, Scerbo, Antonio, Tundo, Paolo, Abrescia, Nicola, Montroni, M., Scalise, G., Costantini, Alessia, Del Prete, M. S., Tirelli, U., Nasti, G., Pastore, G., Ladisa, N., Perulli, L. M., Suter, F., Arici, C., Chiodo, F., Gritti, F. M., Colangeli, V., Fiorini, C., Guerra, L., Carosi, G., Cadeo, G. P., Castelli, F., Minardi, C., Vangi, D., Rizzardini, G., Migliorino, G., Manconi, P. E., Piano, P., Ferraro, T., Scerbo, A., Pizzigallo, E., Ricci, Fiammetta, Rinaldi, E., Pusterla, L., Carnevale, G., Galloni, D., Viganò, P., Mena, M., Ghinelli, F., Sighinolfi, L., Leoncini, F., Mazzotta, F., Ambu, S., Lo Caputo, S., Angarano, G., Grisorio, B., Ferrara, S., Grima, P., Tundo, P., Pagano, G., Piersantelli, N., Alessandrini, A., Piscopo, R., Toti, M., Chigiott, S., Soscia, F., Tacconi, L., Orani, A., Castaldo, G., Scasso, A., Vincenti, A., Scalzini, A., Alessi, F., Moroni, M., Lazzarin, A., Cargnel, A., Vigevani, G. M., Caggese, L., d’Arminio Monforte, A., Bongiovanni, M., Novati, R., Delfanti, F., Merli, S., Pastecchia, C., Moioli, C., Esposito, R., Mussini, C., Abrescia, N., Chirianni, A., Izzo, OMAR CARLO ENRICO, Piazza, M., De Marco, M., Montesarchio, V., Manzillo, E., Nappa, S., Colomba, A., Abbadessa, V., Prestileo, T., Mancuso, S., Filice, G., Minoli, L., Bruno, R., Maserati, R., Pauluzzi, S., Tosti, A., Alberici, F., Sisti, M., Menichetti, F., Smorfa, A., De Stefano, C., Lagala, A., Zauli, T., Ballardini, G., Bonazzi, L., Ursitti, M. A., Ciammarughi, R., Ortolani, P., Ortona, L., Dianzani, F., Antinori, A., Antonucci, G., D’Elia, S., Ippolito, G., Narciso, P., Petrosillo, N., Rezza, G., Vullo, V., De Luca, A., Del Forno, A., Capobianchi, M. R., Zaccarelli, M., De Longis, P., Ciardi, M., Girardi, E., D’Offizi, G., Noto, P., Pezzotti, P., Bugarini, R., Lichter, M., Mura, M. S., Mannazzu, M., Caramello, P., Caramello, A., Soranzo, M. L., Gennero, L., Sciandra, M., Salassa, B., Grossi, P. A., Basilico, C., Poggio, A., Bottari, G., Raise, E., Pasquinucci, S., De Lalla, F., Tositti, G., Resta, F., and Chimienti, A.
- Subjects
Cyclopropanes ,Adult ,Male ,medicine.medical_specialty ,Efavirenz ,Nevirapine ,Settore MED/17 - Malattie Infettive ,Adolescent ,Antiretroviral Therapy ,Pharmacology ,Efficacy ,Cohort Studies ,chemistry.chemical_compound ,Drug Therapy ,Antiretroviral Therapy, Highly Active ,Internal medicine ,Oxazines ,medicine ,Humans ,Immunology and Allergy ,Highly Active ,Viral ,Sida ,Aged ,Acquired Immunodeficiency Syndrome ,biology ,Reverse-transcriptase inhibitor ,business.industry ,Middle Aged ,biology.organism_classification ,Confidence interval ,Benzoxazines ,CD4 Lymphocyte Count ,Infectious Diseases ,chemistry ,Alkynes ,Cohort ,Combination ,RNA, Viral ,RNA ,Drug Therapy, Combination ,Female ,business ,Cohort study ,medicine.drug - Abstract
This nonrandomized study compared the virologic and immunologic responses to potent regimens containing either efavirenz or nevirapine after considering potential systematic differences between patients receiving these drugs. Virologic failure was defined as the first of 2 consecutive measurements of virus load >500 human immunodeficiency virus RNA copies/mL. Of the 694 patients included in the analysis, 460 (66.3%) started nevirapine and 234 (33.7%) started efavirenz. The adjusted relative hazard of virologic failure for patients who started nevirapine, compared with those who started efavirenz, was 2.08 (95% confidence interval, 1.37-3.15; P=.0006). In addition, patients receiving efavirenz tended to recover 5 CD4 cells/microL more per quarter (P=.05). Although comparisons of drug efficacy in nonrandomized studies should be viewed with caution, no results from randomized controlled comparisons of these drugs are thought to be available. The findings of this study are in agreement with those of other observational studies.
- Published
- 2002
49. Lo studio di coorte I.CO.N.A. (Italian CohOrt Naive Antiretrovirals): caratteristiche all’arruolamento dei primi 1676 soggetti
- Author
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DARMINIO MONFORTE, A, Arici, C, Ippolito, G., Rezza, G., Angarano, G., Carosi, G., Vhiodo, F., Dianzani, F., Di Luzio Paparatti, U., Lazzarin, A., Ortona, L., Garattini, L., Musicco, M., Pezzotti, P., Vella, S., Abrescia, N., Aceti, A., Alberici, F., Armignacco, O., Bonazzi, L., Cadeo, G. P., Cadrobbi, P., Caggese, L., Cargnel, A., Carnevale, G., Chirianni, A., Ciammarughi, R., Colomba, A., D'Amato, C., De Lalla, F., D'Elia, S., Dealla Santa, M., De Rienzo, B., De Stefano, C., Ferraro, T., Filice, G., Fiori, G. P., Gavazzeni, G., Ghinelli, F., Gioannini, P., Grilone, W., Grima, P., Grisorio, B., Gritti, F. M., Leoncini, F., Manconi, P. E., Mazzotta, F., Milazzo, F., Minoli, L., Montroni, M., Narciso, P., Orani, A., Pauluzzi, S., Piazza, M., Piersantelli, N., Pizzigallo, E., Poggio, A., Reaise, E., Ranieri, S., Resta, F., Rizzo, F., Rosci, M. A., Scalise, G., Scalzini, A., Scasso, A., Soranzo, M. L., Soscia, F., Suter, F., Tirelli, U., Toti, M., Viganò, P., Vigevani, G. M., Vullo, V., Ravasio, L., Girardi, E., Federico, M. D., Castelli, Francesco, Colangeli, V., Capobianchi, M., Sinnone, M. S., Antinori, A., Boccia, L., Mannazzu, M., Sisti, M., DE LOngis, P., Ursitti, M. A., Vangi, D., Scaggiante, R., Moioli, M. C., Adriani, B., Pan, A., Montesarchio, M., Arlotti, M., Prestileo, T., Palmieri, F., Franzetti, M., Ciardi, M., Smorfa, A., Mussini, C., Armignacco, L., Cosco, L., Patruno Savino, F. A., Torre, D., Sighinolfi, L., Sciandra, M., Giacobbi, D., Tundo, P., Ferrara, S., Guerra, L., Ambu, S., Piano, P., Lo Caputo, S., Rizzardini, G., Maserati, R., Costantini, A., D'Offizi, G. P., Castaldo, G., Tosti, A., Nappa, S., Piscopo, R., Ricci, F., Bottari, V., Pasquinucci, S., Ballardini, G., Chimienti, A., Alessandrini, A., Zaccarelli, M., Del Prete, M. S., Costa, P., Vincenti, A., Salassa, B., Tacconi, L., Bottura, P., Nasti, G., Incandela, L., Ghiselli, G. C., Pusterla, L., Lichtner, M., and Moroni, M.
- Published
- 1997
50. The Predictive Role of Circulating Serum Free Light Chains (sFLC) in HIV-Associated Non Hodgkin's Lymphoma (NHL) and Hodgkin's Disease (HD) and Its Correlation with Effective Combined Antiretroviral Treatment (cART)
- Author
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Bibas, Michele, primary, Trotta, Maria Paola, additional, Lorenzini, Patrizia, additional, Cozzi-Lepri, Alessandro, additional, Borderi, M., additional, Tozzi, Valerio, additional, Galli, Massimo, additional, Angarano, Gioacchino, additional, Montroni, M., additional, Arlotti, M., additional, Carnevale, G., additional, Abrescia, Nicola, additional, Pucillo, Leopoldo Paolo, additional, Monforte, Antonella D'Arminio, additional, and Antinori, Andrea, additional
- Published
- 2010
- Full Text
- View/download PDF
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