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Purpose: Beetroot juice (BRJ) is considered an ergogenic aid with good to strong evidence for improving human performance in sport modalities with similar demands to rugby. However, most of the studies were realized in male athletes with limited evidence in female athletes. Thus, the aim of this study was to explore the acute ingestion of BRJ in female rugby players. Methods: Fourteen semi-professional female rugby players (25.0 ± 3.7 years) belonging to a team from the First Spanish Female Rugby Division participated in this study. Participants were randomly divided into two groups that realized a neuromuscular battery after BRJ (140mL, 12.8 mmol NO3−) or placebo (PLAC, 140 mL, 0.08 mmol NO3−) ingestion on two different days separated by one week between protocols. The neuromuscular test battery consisted of a countermovement jump (CMJ), isometric handgrip strength (i.e., dominant), 10-m and 30-m sprint, agility t-test and Bronco test. Afterwards, participants reported a rate of perception scale (6–20 points) and side effects questionnaire associated with BRJ or PLAC ingestion. Results: Statistically significant improvements were observed in CMJ (7.7%; p = 0.029; ES = 0.62), while no differences were reported in dominant isometric handgrip strength (−1.7%; p = 0.274; ES = −0.20); 10-m and 30-m sprint (0.5–0.8%; p = 0.441–0.588; ES = 0.03–0.18); modified agility t-test (−0.6%; p = 0.503; ES = −0.12) and Bronco test (1.94%; p = 0.459; ES = 0.16). Conclusions: BRJ ingestion could improve neuromuscular performance in the CMJ test, while no differences in sprint (10-m and 30-m sprint test), agility, isometric handgrip strength and endurance performance (i.e., Bronco test) were reported, Banco Santander, Universidad Francisco de Vitoria, Depto. de Radiología, Rehabilitación y Fisioterapia, Fac. de Medicina, TRUE, pub

El zumo de remolacha (ZR) es una fuente nutricional rica en nitrato (NO3 - ) que, una vez ingerido, es reducido a óxido nítrico (ON). El ON posee efectos hipotensores, anti-inflamatorios y provoca mejoras en la eficiencia mitocondrial y en la regulación de la contractilidad muscular. Distintas investigaciones han comprobado que la suplementación con ZR presenta un efecto ergogénico en modalidades de resistencia cardiorrespiratoria y esfuerzos explosivos e intermitentes de alta intensidad. Sin embargo, dado que ninguna revisión ha valorado el efecto de la suplementación con ZR sobre la producción de fuerza muscular, el objetivo de la presente revisión sistemática es analizar el efecto de la suplementación con ZR sobre el rendimiento en la fuerza muscular. La búsqueda mediante palabras clave y conectores booleanos se realizó en las bases de datos Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus y SPORTDiscus. La estrategia de búsqueda empleada fue la siguiente: (nitrate OR beet*) AND (concepto 2) (supplement* OR nutr* OR diet*) AND (concepto 3) (strength OR «resistance exercise» OR «resistance training» OR «muscular power»). Tras la aplicación de los criterios de inclusión, un total de 14 artículos fueron seleccionados para la revisión. En la revisión se ha comprobado como la suplementación con ZR puede tener un efecto ergogénico sobre la producción de fuerza muscular bajo estimulación eléctrica, así como sobre la producción de potencia sobre contracciones isocinéticas únicamente a altas velocidades angulares, siendo el mecanismo explicativo una potenciación de la capacidad contráctil específicamente en las fibras musculares tipo II., Beet juice (BJ) is a nutritional source rich in nitrate (NO3 - ) which, after ingestion, is reduced to nitric oxide (NO). NO has effects such as reduction in arterial pressure, anti-inflammatory effects, enhancement of mitochondrial efficiency, and regulation of muscle contractility. Different studies have reported that BJ supplementation has an ergogenic effect in modalities of cardiorespiratory endurance and explosive and intermittent high intensity efforts. Nevertheless, no review has assessed the effect of BJ supplementation on muscle strength production. Thus, the objective of this systematic review is to analyse the effect of BJ supplementation on muscle strength performance. The search using keywords and Boolean connectors was carried out in the databases Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus, and SPORTDiscus. The search strategy used was the following: (nitrate OR beet *) AND (concept 2) (supplement * OR nutr * OR diet *) AND (concept 3) (strength OR «resistance exercise» OR «resistance training» OR «muscular power «). After the application of the inclusion criteria, a total of 14 articles were selected for review. The review has shown how BJ supplementation can have an ergogenic effect on the production of muscle strength under electrical stimulation, as well as on the production of power over isokinetic contractions only at high angular speeds, the explanatory mechanism being a potentiation of the contractile capacity specifically in type II muscle fibers.

Beet juice (BJ) is a nutritional source rich in nitrate (NO3-) which, after ingestion, is reduced to nitric oxide (NO). NO has effects such as reduction in arterial pressure, anti-inflammatory effects, enhancement of mitochondrial efficiency, and regulation of muscle contractility. Different studies have reported that BJ supplementation has an ergogenic effect in modalities of cardiorespiratory endurance and explosive and intermittent high intensity efforts. Nevertheless, no review has assessed the effect of BJ supplementation on muscle strength production. Thus, the objective of this systematic review is to analyse the effect of BJ supplementation on muscle strength performance. The search using keywords and Boolean connectors was carried out in the databases Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus, and SPORTDiscus. The search strategy used was the following: (nitrate OR beet *) AND (concept 2) (supplement * OR nutr * OR diet *) AND (concept 3) (strength OR «resistance exercise» OR «resistance training» OR «muscular power «). After the application of the inclusion criteria, a total of 14 articles were selected for review. The review has shown how BJ supplementation can have an ergogenic effect on the production of muscle strength under electrical stimulation, as well as on the production of power over isokinetic contractions only at high angular speeds, the explanatory mechanism being a potentiation of the contractile capacity specifically in type II muscle fibers., El zumo de remolacha (ZR) es una fuente nutricional rica en nitrato (NO3-) que, una vez ingerido, es reducido a óxido nítrico (ON). El ON posee efectos hipotensores, anti-inflamatorios y provoca mejoras en la eficiencia mitocondrial y en la regulación de la contractilidad muscular. Distintas investigaciones han comprobado que la suplementación con ZR presenta un efecto ergogénico en modalidades de resistencia cardiorrespiratoria y esfuerzos explosivos e intermitentes de alta intensidad. Sin embargo, dado que ninguna revisión ha valorado el efecto de la suplementación con ZR sobre la producción de fuerza muscular, el objetivo de la presente revisión sistemática es analizar el efecto de la suplementación con ZR sobre el rendimiento en la fuerza muscular. La búsqueda mediante palabras clave y conectores booleanos se realizó en las bases de datos Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus y SPORTDiscus. La estrategia de búsqueda empleada fue la siguiente: (nitrate OR beet*) AND (concepto 2) (supplement* OR nutr* OR diet*) AND (concepto 3) (strength OR «resistance exercise» OR «resistance training» OR «muscular power»). Tras la aplicación de los criterios de inclusión, un total de 14 artículos fueron seleccionados para la revisión. En la revisión se ha comprobado como la suplementación con ZR puede tener un efecto ergogénico sobre la producción de fuerza muscular bajo estimulación eléctrica, así como sobre la producción de potencia sobre contracciones isocinéticas únicamente a altas velocidades angulares, siendo el mecanismo explicativo una potenciación de la capacidad contráctil específicamente en las fibras musculares tipo II.

Bioactive supplements display relevant therapeutic properties when properly applied according to validated molecular effects. Our previous research efforts established the basis to develop a dietary supplement based on a Rosmarinus officinalis supercritical extract. This was enriched in phenolic diterpenes (RE) with proven properties against signaling pathways involved in colon tumorigenesis, and shark liver oil rich in alkylglycerols (AKG) as a bioactive lipid vehicle to improve RE bioavailability and synergize with the potential therapeutic action of the extract. Herein, we have investigated the tolerability and safety of the supplement and the biological and molecular effects from an immuno-nutritional perspective. Sixty healthy volunteers participated in a six week, double-blind, randomized parallel pilot study with two study arms: RE-AKG capsules (CR) and control capsules (CC). Mean age (±SD) of volunteers was 28.32 (±11.39) and 27.5 (±9.04) for the control and the study groups, respectively. Safety of the CR product consumption was confirmed by analyzing liver profile, vital constants, and oxidation markers (LDLox in blood and isoprostanes and thromboxanes in urine). The following were monitored: (1) the phenotyping of plasmatic leukocytes and the ex vivo response of lipopolysaccharide (LPS)-stimulated peripheral blood mononuclear cells (PBMCs); (2) expression of genes associated with immune-modulation, inflammation, oxidative stress, lipid metabolism, and tumorigenesis; and (3) the correlation of selected genetic variants (SNPs) with the differential responses among individuals. The lack of adverse effects on liver profile and oxidation markers, together with adequate tolerability and safe immunological adaptations, provide high-quality information for the potential use of CR as co-adjuvant of therapeutic strategies against colorectal cancer., Ministerio de Economía y Competitividad (MINECO), Comunidad de Madrid, Depto. de Radiología, Rehabilitación y Fisioterapia, Fac. de Medicina, TRUE, pub

The aim of this study is to investigate the acid-base balance when performing a maximal field test of professional soccer players. During the practice of physical exercise in a wide range of intensity, the pH is maintained close to resting values. At higher intensities the pH drops in inverse proportion. The different buffer systems of the body are responsible for these variations. The variables that determine the pH can be divided into independent and dependent, being the study of them essential to understanding the changes in acidbase balance. In this study we analyzed three variables that determine the changes in pH: the partial pressure of CO2 (pPCO2), the concentration of bicarbonate (HCO3 -) and lactate concentration. The determinations were performed on capillary blood in nineteen players while performing an incremental exercise., El objetivo de este estudio es investigar el equilibrio ácido-base al realizar un test de campo máximo en futbolistas profesionales. Durante la práctica de un ejercicio físico, en un amplio rango de intensidad, el pH se mantiene muy próximo a los valores de reposo. A intensidades más elevadas el pH desciende en relación inversa. Los diferentes sistemas de amortiguación del organismo son los responsables de estas variaciones. Las variables que determinan el pH pueden ser divididas en independientes y dependientes, siendo el estudio de las mismas esencial para comprender las variaciones en el equilibrio ácidobase. En el presente trabajo se analizaron tres de las variables que determinan las modificaciones en el pH: la presión parcial de CO2 (pPCO2), la concentración de bicarbonato (HCO3 -) y la concentración de lactato. Las determinaciones fueron realizadas en sangre capilar en diecinueve jugadores durante la realización de un ejercicio incremental.