796 results on '"Montero L"'
Search Results
2. Publisher Correction: Multidisciplinary approach to the study of large-format oil paintings
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Calderón-Mesén, P., Jaikel-Víquez, D., Barrantes-Madrigal, M. D., Sánchez-Solís, J., Mena-Vega, J. P., Arguedas-Molina, J., Ureña-Alvarado, K., Maynard-Hernández, G., Santamaría-Montero, L., Cob-Delgado, M., Angulo-Pardo, E., Vallejo, Felipe, Sandoval, M. I., Durán-Quesada, A. M., Redondo-Solano, M., and Herrera-Sancho, O. A.
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- 2023
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3. Multidisciplinary approach to the study of large-format oil paintings
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Calderón-Mesén, P., Jaikel-Víquez, D., Barrantes-Madrigal, M. D., Sánchez-Solís, J., Mena-Vega, J. P., Arguedas-Molina, J., Ureña-Alvarado, K., Maynard-Hernández, G., Santamaría-Montero, L., Cob-Delgado, M., Angulo-Pardo, E., Vallejo, Felipe, Sandoval, M. I., Durán-Quesada, A. M., Redondo-Solano, M., and Herrera-Sancho, O. A.
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- 2023
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4. POS1007 THE INVOLVEMENT OF THE C5 AND C5AR1 GENES IN THE PATHOGENESIS OF IgAV
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Batista-Liz, J. C., primary, Calvo-Río, V., additional, Sebastián Mora-Gil, M., additional, Sevilla-Pérez, B., additional, Callejas, J. L., additional, Leonardo, M. T., additional, Peñalba, A., additional, Cabero, M. J., additional, Narváez, J., additional, Martín-Penagos, L., additional, Belmar-Vega, L., additional, Gomez-Fernandez, C., additional, Caminal-Montero, L., additional, Collado, P., additional, Quiroga Colina, P., additional, Vicente-Rabaneda, E., additional, Rubio-Romero, E., additional, León Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Castañeda, S., additional, Blanco, R., additional, Pulito-Cueto, V., additional, and López-Mejías, R., additional
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- 2024
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5. AB1240 NLRP3 AND CASP1 GENES AS DISCRIMINATORY MARKERS BETWEEN IGA VASCULITIS AND IGA NEPHROPATHY?
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Batista-Liz, J. C., primary, Sebastián Mora-Gil, M., additional, Gabrie, L., additional, Gálvez-Sánchez, R., additional, Leonardo, M. T., additional, Peñalba, A., additional, Sevilla-Pérez, B., additional, Callejas, J. L., additional, Caminal-Montero, L., additional, Narváez, J., additional, Martín-Penagos, L., additional, Belmar-Vega, L., additional, Collado, P., additional, Fernández-Nebro, A., additional, Díaz-Cordoves, G., additional, Quiroga Colina, P., additional, Vicente-Rabaneda, E., additional, Cigarrán, S., additional, Calviño, J., additional, Cobelo, C., additional, Rubio-Romero, E., additional, León Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Castañeda, S., additional, Blanco, R., additional, Pulito-Cueto, V., additional, and López-Mejías, R., additional
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- 2024
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6. AB0806 HUMORAL RESPONSES AGAINST HDL ARE LINKED TO UNFAVORABLE LIPOPROTEIN TRAITS AND LIPID SPECIES IN PRIMARY SJÖGREN SYNDROME
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Rodríguez-Carrio, J., primary, Suárez, S., additional, López, P., additional, Pérez-Álvarez, Á. I., additional, Caminal-Montero, L., additional, and Suárez, A., additional
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- 2024
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7. POS0256 THE FIRST METHYLOME PROFILING STUDY OF B-CELLS IN IGA VASCULITIS REVEALED POTENTIAL BIOMARKERS OF DISEASE SUSCEPTIBILITY
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López-Mejías, R., primary, Pulito-Cueto, V., additional, Fernández Rengel, I., additional, Terron Camero, L. C., additional, Batista-Liz, J., additional, Sebastián Mora-Gil, M., additional, Leonardo, M. T., additional, Peñalba, A., additional, Martín-Penagos, L., additional, Belmar-Vega, L., additional, Gomez-Fernandez, C., additional, Gabrie, L., additional, Gálvez-Sánchez, R., additional, Caminal-Montero, L., additional, Turrión, A. I., additional, Quiroga Colina, P., additional, Vicente-Rabaneda, E., additional, Sevilla-Pérez, B., additional, Callejas, J. L., additional, Andrés-León, E., additional, Martin, J., additional, Márquez, A., additional, Castañeda, S., additional, and Blanco, R., additional
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- 2024
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8. Tropical Dominating Sets in Vertex-Coloured Graphs
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d'Auriac, J. -A. Angles, Bujtas, Cs., Maftouhi, A. El, Karpinski, M., Manoussakis, Y., Montero, L., Narayanan, N., Rosaz, L., Thapper, J., and Tuza, Zs.
- Subjects
Computer Science - Discrete Mathematics - Abstract
Given a vertex-coloured graph, a dominating set is said to be tropical if every colour of the graph appears at least once in the set. Here, we study minimum tropical dominating sets from structural and algorithmic points of view. First, we prove that the tropical dominating set problem is NP-complete even when restricted to a simple path. Then, we establish upper bounds related to various parameters of the graph such as minimum degree and number of edges. We also give upper bounds for random graphs. Last, we give approximability and inapproximability results for general and restricted classes of graphs, and establish a FPT algorithm for interval graphs., Comment: 19 pages, 4 figures
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- 2015
9. Peer Learning and Research Culture Within Student Organizations in Engineering: Students' Perceptions.
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Velarde, K. Galantini, Cáceres Montero, L., and Pachas, A.
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PSYCHOLOGY of students ,CAREER development ,CORPORATE culture ,STUDENT organizations ,ENGINEERING students - Abstract
Learning-centered models require using interactive methods, such as peer learning. In this context, student organizations are introduced as groups of students managed as autonomous extracurricular spaces in which they enrich their training process upon practical issues that promote peer learning, while encouraging lifelong learning (LL). Thus, this research explores undergraduate engineering students' perceptions about the influence of student organizations on the promotion of undergraduate research culture through a survey. Results have indicated that 91% of the surveyed students think that research is encouraged within these spaces, and 79% perceive that these organizations have provided them with the necessary support to start a research project. Finally, 87% have begun to consider research as an important factor for their professional development, in accordance with LL. Therefore, it was concluded that the promotion of undergraduate research culture within these organizations strengthens students' intention to develop their final degree project as a research paper. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Pregnancy loss in beef cattle: A meta-analysis
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Reese, S.T., Franco, G.A., Poole, R.K., Hood, R., Fernadez Montero, L., Oliveira Filho, R.V., Cooke, R.F., and Pohler, K.G.
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- 2020
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11. 19. USE OF FERROMAGNETIC SEED SIRIUS PINTUITION® ON THE LOCALIZATION OF NON-PALPABLE TUMORS: PILOT STUDY
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Santana Valenciano, A, primary, Rivas Fidalgo, S, additional, Corral Moreno, S, additional, Gamero Medina, V, additional, Pérez Izquierdo, C B, additional, Nieto Martos, M R, additional, Mena Mateos, A, additional, Cabañas Montero, L J, additional, and Fernández Cebrián, J M, additional
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- 2024
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12. 14. “TEXTBOOK OUTCOMES” IN SURGICAL APPROACH OF DIFFERENTIATED THYROID CANCER
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Santana Valenciano, A, primary, Porrero Guerrero, B, additional, Luengo Pierrard, P, additional, Mena Mateos, A, additional, Nieto Martos, M R, additional, Pérez Izquierdo, C B, additional, Cabañas Montero, L J, additional, and Fernández Cebrián, J M, additional
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- 2024
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13. Shape-dependent antifungal activity of ZnO particles against phytopathogenic fungi
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Pariona, Nicolaza, Paraguay-Delgado, F., Basurto-Cereceda, Sofia, Morales-Mendoza, J. E., Hermida-Montero, L. A., and Mtz-Enriquez, Arturo I.
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- 2020
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14. Fusing mobile phone data with other data sources to generate input OD matrices for transport models
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Montero, L., Ros-Roca, X., Herranz, R., and Barceló, J.
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- 2019
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15. Treatment Strategies and Clinical Outcomes in patients with Localized and Advanced Bladder Cancer: Real-World Data from a Single Spanish Institution.
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Sánchez-Camacho, A., primary, Torres Zurita, A., additional, Vázquez Montero, L., additional, Flores Raposo, J., additional, Nogales Fernández, E., additional, and Virizuela Echaburu, J.A., additional
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- 2023
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16. Analysis of vortex core generation in pipe flows under different Reynolds number conditions
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Salvador, F. J., Carreres, M., Quintero, P., and González-Montero, L. A.
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- 2021
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17. Predictive Factors of the Use of Rituximab and Belimumab in Spanish Lupus Patients
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Capdevila, O., primary, Mitjavila, F., additional, Espinosa, G., additional, Caminal-Montero, L., additional, Marín-Ballvè, A., additional, González León, R., additional, Castro, A., additional, Canora, J., additional, Pinilla, B., additional, Fonseca, E., additional, and Ruiz-Irastorza, G., additional
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- 2023
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18. Analysis and Operational Challenges of Dynamic Ride Sharing Demand Responsive Transportation Models
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Linares, M.P., Barceló, J., Carmona, C., and Montero, L.
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- 2017
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19. Evaluating watershed health in Costa Rican national parks and protected areas
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Jovanelly, T. J., Rodríguez-Montero, L., Sánchez-Gutiérrez, R., Mena-Rivera, L., and Thomas, D.
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- 2020
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20. Pollinator Preferences for Floral Volatiles Emitted by Dimorphic Anthers of a Buzz-Pollinated Herb
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Solís-Montero, L., Cáceres-García, S., Alavez-Rosas, D., García-Crisóstomo, J. F., Vega-Polanco, M., Grajales-Conesa, J., and Cruz-López, L.
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- 2018
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21. AB0173 MUCOSAL IMMUNE DEFENCE POLYMORPHISMS: RELEVANT PLAYERS IN IGA VASCULITIS?
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Pulito-Cueto, V., primary, Remuzgo Martinez, S., additional, Genre Romero, F., additional, Sevilla, B., additional, Ortego, N., additional, Leonardo, M., additional, Peñalba, A., additional, Narváez, J., additional, Martín-Penagos, L., additional, Belmar-Vega, L., additional, Gomez-Fernandez, C., additional, Sebastián Mora-Gil, M., additional, Caminal Montero, L., additional, Collado, P., additional, De Argila, D., additional, Rodriguez-Jimenez, P., additional, Vicente-Rabaneda, E. F., additional, Rubio-Romero, E., additional, Leon Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Martin Ibanez, J., additional, Castañeda, S., additional, González-Gay, M. A., additional, Blanco, R., additional, and López-Mejías, R., additional
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- 2023
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22. AB0166 IGAV AND IGAN: A SINGLE ENTITY REGARDING CD40, BLK AND BANK1 POLYMORPHISMS
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Pulito-Cueto, V., primary, Genre Romero, F., additional, Remuzgo Martinez, S., additional, Sevilla, B., additional, Ortego, N., additional, Leonardo, M., additional, Peñalba, A., additional, Narváez, J., additional, Martín-Penagos, L., additional, Belmar-Vega, L., additional, Gomez-Fernandez, C., additional, Sebastián Mora-Gil, M., additional, Caminal Montero, L., additional, Collado, P., additional, Fernandez-Nebro, A., additional, Diaz-Cordobes, G., additional, Cigarrán, S., additional, Calviño, J., additional, Cobelo, C., additional, De Argila, D., additional, Sanchez Perez, J., additional, Uriarte-Ecenarro, M., additional, Rubio-Romero, E., additional, Leon Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Martin Ibanez, J., additional, Castañeda, S., additional, González-Gay, M. A., additional, Blanco, R., additional, and López-Mejías, R., additional
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- 2023
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23. Predictive Factors of the Use of Rituximab and Belimumab in Spanish Lupus Patients
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Universitat Rovira i Virgili, Capdevila, O; Mitjavila, F; Espinosa, G; Caminal-Montero, L; Marín-Ballvè, A; León, RG; Castro, A; Canora, J; Pinilla, B; Fonseca, E; Ruiz-Irastorza, G; RELES; Autoimmune Dis Study Grp GEAS; Spanish Soc Internal Med, Universitat Rovira i Virgili, and Capdevila, O; Mitjavila, F; Espinosa, G; Caminal-Montero, L; Marín-Ballvè, A; León, RG; Castro, A; Canora, J; Pinilla, B; Fonseca, E; Ruiz-Irastorza, G; RELES; Autoimmune Dis Study Grp GEAS; Spanish Soc Internal Med
- Abstract
Objectives: To analyze the characteristics and the predictive factors of the use of rituximab and belimumab in daily practice in patients from the inception cohort Registro Espanol de Lupus (RELES). Material and methods: The study included 518 patients. We considered patients treated with biologics who received at least one dose of rituximab or belimumab, and possible indications of those manifestations registered at the same time or in the previous 2 months of the start of the therapy. Results: In our cohort, 37 (7%) patients received at least one biological treatment. Rituximab was prescribed in 26 patients and belimumab in 11. Rituximab was mainly prescribed for hemolytic anemia or thrombocytopenia (11 patients, 42%), lupus nephritis and neuropsychiatric lupus (5 patients each, 19%). Belimumab was mostly used for arthritis (8 patients, 73%). In the univariate analysis, the predictive factors at diagnosis for the use of biologic therapy were younger age (p = 0.022), a higher SLEDAI (p = 0.001) and the presence of psychosis (p = 0.011), organic mental syndrome (SOCA) (p = 0.006), hemolytic anemia (p = 0.001), or thrombocytopenia (p = 0.01). In the multivariant model, only younger age, psychosis, and hemolytic anemia were independent predictors of the use of biologics. Conclusions: Rituximab is usually given to patients with hematological, neuropsychiatric and renal involvement and belimumab for arthritis. Psychosis, hemolytic anemia and age at the diagnosis of lupus were independent predictive factors of the use of biological agents. Their global effects are beneficial, with a significant reduction in SLE activity and a low rate of side effects.
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- 2023
24. Downstream valorization and comprehensive two-dimensional liquid chromatography-based chemical characterization of bioactives from black chokeberries (Aronia melanocarpa) pomace
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Brazdauskas, T., Montero, L., Venskutonis, P.R., Ibañez, E., and Herrero, M.
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- 2016
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25. TRATAMIENTO ANTIBIÓTICO SUPRESIVO EN PACIENTES CON ENDOCARDITIS INFECCIOSA
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García Carús, E., primary, Caminal Montero, L., additional, Fernández Suárez, J., additional, Salmerón Menéndez, C., additional, Alaguero, M., additional, Fernández Domínguez, J., additional, Villa Bajo, L., additional, Rodríguez Esteban, A., additional, García, L., additional, and Rodríguez-Guardado, A., additional
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- 2023
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26. Determination of the Stress Intensity Factor of an elliptical breathing crack in a rotating shaft
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Rubio, P., Rubio, L., Muñoz-Abella, B., and Montero, L.
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- 2015
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27. ANCA-associated hypertrophic pachymeningitis, a central nervous system limited type of systemic vasculitis
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Morán-Castaño, C, primary, Suárez-Díaz, S, additional, Álvarez-Marcos, C A, additional, Martínez-Camblor, L, additional, Criado-Antón, Á, additional, Yllera-Gutiérrez, C, additional, and Caminal-Montero, L, additional
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- 2022
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28. Multidisciplinary approach to the study of artworks: environmental conditions, color palette, microbial colonization and nannofossils inLas Musaspainting
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Calderón-Mesén, P., primary, Jaikel-Víquez, D., additional, Barrantes-Madrigal, M.D., additional, Sánchez-Solís, J., additional, Mena-Vega, J., additional, Arguedas-Molina, J., additional, Ureña-Alvarado, K., additional, Maynard-Hernández, G., additional, Santamaría-Montero, L., additional, Cob-Delgado, M., additional, Angulo-Pardo, E., additional, Vallejo, Felipe, additional, Sandoval-Gutiérez, M., additional, Durán-Quesada, A. M., additional, Redondo-Solano, M., additional, and Herrera-Sancho, O.A., additional
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- 2022
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29. Death in hospital following ICU discharge: insights from the LUNG SAFE study
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Madotto, F, Mcnicholas, B, Rezoagli, E, Pham, T, Laffey, J, Bellani, G, Pesenti, A, Brochard, L, Esteban, A, Gattinoni, L, van Haren, F, Ranieri, M, Rubenfeld, G, Thompson, B, Slutsky, A, Rios, F, Faruq, M, Sottiaux, T, Depuydt, P, Lora, F, Azevedo, C, Fan, E, Bugedo, G, Qiu, H, Gonzalez, M, Silesky, J, Cerny, V, Nielsen, J, Jibaja, M, Wrigge, H, Matamis, D, Ranero, J, Gomersall, C, Amin, P, Hashemian, S, Clarkson, K, Kurahashi, K, Koh, Y, Villagomez, A, Zeggwagh, A, Heunks, L, Laake, J, Kashif, W, Synclair, J, Palo, J, do Vale Fernandes, A, Sandesc, D, Arabi, Y, Bumbasierevic, V, Nin, N, Lorente, J, Larsson, A, Piquilloud, L, Patjanasoontorn, B, Abroug, F, Mcauley, D, Mcnamee, L, Hurtado, J, Bajwa, E, Dempaire, G, Francois, G, Rabboni, F, Conti, S, Sula, H, Nunci, L, Cani, A, Zazu, A, Dellera, C, Insaurralde, C, Alejandro, R, Daldin, J, Vinzio, M, Fernandez, R, Cardonnet, L, Bettini, L, Bisso, M, Osman, E, Setten, M, Lovazzano, P, Alvarez, J, Villar, V, Pozo, N, Grubissich, N, Plotnikow, G, Vasquez, D, Ilutovich, S, Tiribelli, N, Chena, A, Pellegrini, C, Saenz, M, Estenssoro, E, Brizuela, M, Gianinetto, H, Gomez, P, Cerrato, V, Bezzi, M, Borello, S, Loiacono, F, Fernandez, A, Knowles, S, Reynolds, C, Inskip, D, Miller, J, Kong, J, Whitehead, C, Bihari, S, Seven, A, Krstevski, A, Rodgers, H, Millar, R, Mckenna, T, Bailey, I, Hanlon, G, Aneman, A, Lynch, J, Azad, R, Neal, J, Woods, P, Roberts, B, Kol, M, Wong, H, Riss, K, Staudinger, T, Wittebole, X, Berghe, C, Bulpa, P, Dive, A, Verstraete, R, Lebbinck, H, Vermassen, J, Meersseman, P, Ceunen, H, Rosa, J, Beraldo, D, Piras, C, Rampinelli, A, Nassar, N, Mataloun, S, Moock, M, Thompson, M, Goncalves, C, Antonio, A, Ascoli, A, Biondi, R, Fontenele, D, Nobrega, D, Sales, V, Shindhe, S, Aiman, D, Ismail, B, Beloncle, F, Davies, K, Cirone, R, Manoharan, V, Ismail, M, Goligher, E, Jassal, M, Ferguson, N, Nishikawa, E, Javeed, A, Curley, G, Rittayamai, N, Parotto, M, Mehta, S, Knoll, J, Pronovost, A, Canestrini, S, Bruhn, A, Garcia, P, Aliaga, F, Farias, P, Yumha, J, Ortiz, C, Salas, J, Saez, A, Vega, L, Labarca, E, Martinez, F, Carreno, N, Lora, P, Liu, H, Liu, L, Tang, R, Luo, X, An, Y, Zhao, H, Gao, Y, Zhai, Z, Ye, Z, Wang, W, Li, W, Li, Q, Zheng, R, Yu, W, Shen, J, Li, X, Yu, T, Lu, W, Wu, Y, Huang, X, He, Z, Lu, Y, Han, H, Zhang, F, Sun, R, Wang, H, Qin, S, Zhu, B, Zhao, J, Liu, J, Li, B, Zhou, F, Zhang, X, Li-Xin, Z, Xin-Hua, Q, Jiang, L, Zhao, X, Li, Y, Wang, C, Yao, Q, Yu, R, Chen, K, Shao, H, Qin, B, Huang, Q, Zhu, W, Hang, A, Hua, M, Xu, Y, Di, Y, Ling, L, Qin, T, Wang, S, Qin, J, Han, Y, Zhou, S, Vargas, M, Jimenez, J, Rojas, M, Solis-Quesada, J, Ramirez-Alfaro, C, Maca, J, Sklienka, P, Gjedsted, J, Christiansen, A, Villamagua, B, Llano, M, Burtin, P, Buzancais, G, Beuret, P, Pelletier, N, Mortaza, S, Mercat, A, Chelly, J, Jochmans, S, Terzi, N, Daubin, C, Carteaux, G, de Prost, N, Chiche, J, Daviaud, F, Fartoukh, M, Barberet, G, Biehler, J, Dellamonica, J, Doyen, D, Arnal, J, Briquet, A, Klasen, F, Papazian, L, Follin, A, Roux, D, Messika, J, Kalaitzis, E, Dangers, L, Combes, A, Au, S, Beduneau, G, Carpentier, D, Zogheib, E, Dupont, H, Ricome, S, Santoli, F, Besset, S, Michel, P, Gelee, B, Danin, P, Goubaux, B, Crova, P, Phan, N, Berkelmans, F, Badie, J, Tapponnier, R, Gally, J, Khebbeb, S, Herbrecht, J, Schneider, F, Declercq, P, Rigaud, J, Duranteau, J, Harrois, A, Chabanne, R, Marin, J, Constantin, J, Thibault, S, Ghazi, M, Boukhazna, M, Zein, S, Richecoeur, J, Combaux, D, Grelon, F, Le Moal, C, Sauvadet, E, Robine, A, Lemiale, V, Reuter, D, Dres, M, Demoule, A, Goldgran-Toledano, D, Baboi, L, Guerin, C, Lohner, R, Krassler, J, Schafer, S, Zacharowski, K, Meybohm, P, Reske, A, Simon, P, Hopf, H, Schuetz, M, Baltus, T, Papanikolaou, M, Papavasilopoulou, T, Zacharas, G, Ourailogloy, V, Mouloudi, E, Massa, E, Nagy, E, Stamou, E, Kiourtzieva, E, Oikonomou, M, Avila, L, Cortez, C, Citalan, J, Jog, S, Sable, S, Shah, B, Gurjar, M, Baronia, A, Memon, M, Muthuchellappan, R, Ramesh, V, Shenoy, A, Unnikrishnan, R, Dixit, S, Rhayakar, R, Ramakrishnan, N, Bhardwaj, V, Mahto, H, Sagar, S, Palaniswamy, V, Ganesan, D, Jamaati, H, Heidari, F, Meaney, E, Nichol, A, Knapman, K, O'Croinin, D, Dunne, E, Breen, D, Jaafar, R, Dwyer, R, Amir, F, Ajetunmobi, O, O'Muircheartaigh, A, Black, C, Treanor, N, Collins, D, Altaf, W, Zani, G, Fusari, M, Spadaro, S, Volta, C, Graziani, R, Brunettini, B, Palmese, S, Formenti, P, Umbrello, M, Lombardo, A, Pecci, E, Botteri, M, Savioli, M, Protti, A, Mattei, A, Schiavoni, L, Tinnirello, A, Todeschini, M, Giaccone, P, Giarratano, A, Cortegiani, A, Sher, S, Rossi, A, Antonelli, M, Montini, L, Casalena, P, Scafetti, S, Panarello, G, Occhipinti, G, Patroniti, N, Pozzi, M, Biscione, R, Poli, M, Raimondi, F, Albiero, D, Crapelli, G, Beck, E, Pota, V, Schiavone, V, Molin, A, Tarantino, F, Monti, G, Frati, E, Mirabella, L, Cinnella, G, Fossali, T, Colombo, R, Pattarino, P, Mojoli, F, Braschi, A, Borotto, E, Cracchiolo, A, Palma, D, 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G., Solis-Quesada J. E., Ramirez-Alfaro C. M., Maca J., Sklienka P., Gjedsted J., Christiansen A., Villamagua B. G., Llano M., Burtin P., Buzancais G., Beuret P., Pelletier N., Mortaza S., Mercat A., Chelly J., Jochmans S., Terzi N., Daubin C., Carteaux G., de Prost N., Chiche J. -D., Daviaud F., Fartoukh M., Barberet G., Biehler J., Dellamonica J., Doyen D., Arnal J. -M., Briquet A., Klasen F., Papazian L., Follin A., Roux D., Messika J., Kalaitzis E., Dangers L., Combes A., Au S. -M., Beduneau G., Carpentier D., Zogheib E. H., Dupont H., Ricome S., Santoli F. L., Besset S. L., Michel P., Gelee B., Danin P. -E., Goubaux B., Crova P. J., Phan N. T., Berkelmans F., Badie J. C., Tapponnier R., Gally J., Khebbeb S., Herbrecht J. -E., Schneider F., Declercq P. -L. M., Rigaud J. -P., Duranteau J., Harrois A., Chabanne R., Marin J., Constantin J. -M., Thibault S., Ghazi M., Boukhazna M., Zein S. O., Richecoeur J. R., Combaux D. M., Grelon F., Le Moal C., Sauvadet E. P., Robine A., Lemiale V., Reuter D., Dres M., Demoule A., Goldgran-Toledano D., Baboi L., Guerin C., Lohner R., Krassler J., Schafer S., Zacharowski K. D., Meybohm P., Reske A. W., Simon P., Hopf H. -B. F., Schuetz M., Baltus T., Papanikolaou M. N., Papavasilopoulou T. G., Zacharas G. A., Ourailogloy V., Mouloudi E. K., Massa E. V., Nagy E. O., Stamou E. E., Kiourtzieva E. V., Oikonomou M. A., Avila L. E., Cortez C. A., Citalan J. E., Jog S. A., Sable S. D., Shah B., Gurjar M., Baronia A. K., Memon M., Muthuchellappan R., Ramesh V. J., Shenoy A., Unnikrishnan R., Dixit S. B., Rhayakar R. V., Ramakrishnan N., Bhardwaj V. K., Mahto H. L., Sagar S. V., Palaniswamy V., Ganesan D., Jamaati H., Heidari F., Meaney E. A., Nichol A., Knapman K. M., O'Croinin D., Dunne E. S., Breen D. M., Clarkson K. P., Jaafar R. F., Dwyer R., Amir F., Ajetunmobi O. O., O'Muircheartaigh A. C., Black C. S., Treanor N., Collins D. V., Altaf W., Zani G., Fusari M., Spadaro S., Volta C. A., Graziani R., Brunettini B., Palmese S., Formenti P., Umbrello M., Lombardo A., Pecci E., Botteri M., Savioli M., Protti A., Mattei A., Schiavoni L., Tinnirello A., Todeschini M., Giaccone P. P., Giarratano A., Cortegiani A., Sher S., Rossi A., Antonelli M. M., Montini L. M., Casalena P., Scafetti S., Panarello G., Occhipinti G., Patroniti N., Pozzi M., Biscione R. R., Poli M. M., Raimondi F., Albiero D., Crapelli G., Beck E., Pota V., Schiavone V., Molin A., Tarantino F., Monti G., Frati E., Mirabella L., Cinnella G., Fossali T., Colombo R., Pattarino P. T. I., Mojoli F., Braschi A., Borotto E. E., Cracchiolo A. N., Palma D. M., Raponi F., Foti G., Vascotto E. R., Coppadoro A., Brazzi L., Floris L., Iotti G. A., Venti A., Yamaguchi O., Takagi S., Maeyama H. N., Watanabe E., Yamaji Y., Shimizu K., Shiozaki K., Futami S., Ryosuke S., Saito K., Kameyama Y., Ueno K., Izawa M., Okuda N., Suzuki H., Harasawa T., Nasu M., Takada T., Ito F., Nunomiya S., Koyama K., Abe T., Andoh K., Kusumoto K., Hirata A., Takaba A., Kimura H., Matsumoto S., Higashijima U., Honda H., Aoki N., Imai H., Ogino Y., Mizuguchi I., Ichikado K., Nitta K., Mochizuki K., Hashida T., Tanaka H., Nakamura T., Niimi D., Ueda T., Kashiwa Y., Uchiyama A., Sabelnikovs O., Oss P., Haddad Y., Liew K. Y., Namendys-Silva S. A., Jarquin-Badiola Y. D., Sanchez-Hurtado L. A., Gomez-Flores S. S., Marin M. C., Villagomez A. J., Lemus J. S., Fierro J. M., Cervantes M. R., Mejia F. J. F., Dector D., Dector D. M., Gonzalez D. R., Estrella C. R., Sanchez-Medina J. R., Ramirez-Gutierrez A., George F. G., Aguirre J. S., Buensuseso J. A., Poblano M., University M. V., Dendane T., Balkhi H., Elkhayari M., Samkaoui N., Ezzouine H., Benslama A., Amor M., Maazouzi W., Cimic N., Beck O., Bruns M. M., Schouten J. A., Rinia M., Raaijmakers M., Van Wezel H. M., Heines S. J., Strauch U., Buise M. P., Simonis F. D., Schultz M. J., Goodson J. C., Browne T. S., Navarra L., Hunt A., Hutchison R. A., Bailey M. B., Newby L., Mcarthur C., Kalkoff M., Mcleod A., Casement J., Hacking D. J., Andersen F. H., Dolva M. S., Barratt-Due A., Noremark K. A. L., Soreide E., Sjobo B. A., Guttormsen A. B., Yoshido H. H. L., Aguilar R. Z., Oscanoa F. A. M., Alisasis A. U., Robles J. B., Pasanting-Lim R. A. B., Tan B. C., Andruszkiewicz P., Jakubowska K., Coxo C. M., Alvarez A. M., Oliveira B. S., Montanha G. M., Barros N. C., Pereira C. S., Messias A. M., Monteiro J. M., Araujo A. M., Catorze N. T., Marum S. M., Bouw M. J., Gomes R. M., Brito V. A., Castro S., Estilita J. M., Barros F. M., Serra I. M., Martinho A. M., Tomescu D. R., Marcu A., Bedreag O. H., Papurica M., Corneci D. E., Negoita S. I., Grigoriev E., Gritsan A. I., Gazenkampf A. A., Almekhlafi G., Albarrak M. M., Mustafa G. M., Maghrabi K. A., Salahuddin N., Aisa T. M., Al Jabbary A. S., Tabhan E., Arabi Y. M., Trinidad O. A., Al Dorzi H. M., Tabhan E. E., Bolon S., Smith O., Mancebo J., Aguirre-Bermeo H., Lopez-Delgado J. C., Esteve F., Rialp G., Forteza C., De Haro C., Artigas A., Albaiceta G. M., De Cima-Iglesias S., Seoane-Quiroga L., Ceniceros-Barros A., Ruiz-Aguilar A. L., Claraco-Vega L. M., Soler J. A., del Carmen Lorente M., Hermosa C., Gordo F., Prieto-Gonzalez M., Lopez-Messa J. B., Perez M. P., Perez C. P., Allue R. M., Roche-Campo F., Ibanez-Santacruz M., Temprano S., Pintado M. C., De Pablo R., Gomez P. R. A., Ruiz S. R., Moles S. I., Jurado M. aT., Arizmendi A., Piacentini E. A., Franco N., Honrubia T., Cheng M. P., Losada E. P., Blanco J., Yuste L. J., Carbayo-Gorriz C., Cazorla-Barranquero F. G., Alonso J. G., Alda R. S., Algaba A., Navarro G., Cereijo E., Diaz-Rodriguez E., Marcos D. P., Montero L. A., Para L. H., Sanchez R. J., Navalpotro M. A. B., Abad R. D., lez R. M. G. A., Toribio D. P., Castro A. G., Artiga M. J. D., Penuelas O., Roser T. P., Olga M. F., Curto E. G., Sanchez R. M., Imma V. P., Elisabet G. M., Claverias L., Magret M., Pellicer A. M., Rodriguez L. L., Sanchez-Ballesteros J., Gonzalez-Salamanca A., Jimenez A. G., Huerta F. P., Diaz J. C. J. S., Lopez E. B., Moya D. D. L., Alfonso A. A. T., Luis P. S. E., Cesar P. S., Rafael S. I., Virgilio C. G., Recio N. N., Adamsson R. O., Rylander C. C., Holzgraefe B., Broman L. M., Wessbergh J., Persson L., Schioler F., Kedelv H., Tibblin A. O., Appelberg H., Hedlund L., Helleberg J., Eriksson K. E., Glietsch R., Larsson N., Nygren I., Nunes S. L., Morin A. -K., Kander T., Adolfsson A., Zender H. O., Leemann-Refondini C., Elatrous S., Bouchoucha S., Chouchene I., Ouanes I., Marsa L., Souissi A. B., Kamoun S., Demirkiran O., Aker M., Erbabacan E., Ceylan I., Girgin N. K., Ozcelik M., Unal N., Meco B. C., Akyol O. O., Derman S. S., Kennedy B., Parhar K., Srinivasa L., McAuley D., Hopkins P., Mellis C., Kakar V., Hadfield D., Vercueil A., Bhowmick K., Humphreys S. K., Ferguson A., Mckee R., Raj A. S., Fawkes D. A., Watt P., Twohey L., Thomas R. R. J. M., Morton A., Kadaba V., Smith M. J., Hormis A. P., Kannan S. G., Namih M., Reschreiter H., Camsooksai J., Kumar A., Rugonfalvi S., Nutt C., Oneill O., Seasman C., Dempsey G., Scott C. J., Ellis H. E., Mckechnie S., Hutton P. J., Di Tomasso N. N., Vitale M. N., Griffin R. O., Dean M. N., Cranshaw J. H., Willett E. L., Ioannou N., Gillis S., Csabi P., Macfadyen R., Dawson H., Preez P. D., Williams A. J., Boyd O., De Gordoa L. O. -R., Bramall J., Symmonds S., Chau S. K., Wenham T., Szakmany T., Toth-Tarsoly P., Mccalman K. H., Alexander P., Stephenson L., Collyer T., Chapman R., Cooper R., Allan R. M., Sim M., Wrathall D. W., Irvine D. A., Zantua K. S., Adams J. C., Burtenshaw A. J., Sellors G. P., Welters I. D., Williams K. E., Hessell R. J., Oldroyd M. G., Battle C. E., Pillai S., Kajtor I., Sivashanmugavel M., Okane S. C., Donnelly A., Frigyik A. D., Careless J. P., May M. M., Stewart R., Trinder T. J., Hagan S. J., Wise M. P., Cole J. M., MacFie C. C., Dowling A. T., Nunez E., Pittini G., Rodriguez R., Imperio M. C., Santos C., Deicas A., Serra C., Uppalapati A., Kamel G., Banner-Goodspeed V. M., Beitler J. R., Mukkera S. R., Kulkarni S., Lee J., Mesar T., Shinn Iii J. O., Gomaa D., Tainter C., Yeatts D. J., Warren J., Lanspa M. J., Miller R. R., Grissom C. K., Brown S. M., Bauer P. R., Gosselin R. J., Kitch B. T., Cohen J. E., Beegle S. H., Gueret R. M., Tulaimat A., Choudry S., Stigler W., Batra H., Huff N. G., Lamb K. D., Oetting T. W., Mohr N. M., Judy C., Saito S., Kheir F. M., Kheir F., Schlichting A. B., Delsing A., Crouch D. R., Elmasri M., Ismail D., Dreyer K. R., Blakeman T. C., Baron R. M., Grijalba C. Q., Hou P. C., Seethala R., Aisiku I., Henderson G., Frendl G., Hou S. -K., Owens R. L., Schomer A., Bumbasirevic V., Jovanovic B., Surbatovic M., and Veljovic M.
- Abstract
Background To determine the frequency of, and factors associated with, death in hospital following ICU discharge to the ward. Methods The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE study was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted across 459 ICUs from 50 countries globally. This study aimed to understand the frequency and factors associated with death in hospital in patients who survived their ICU stay. We examined outcomes in the subpopulation discharged with no limitations of life sustaining treatments ('treatment limitations'), and the subpopulations with treatment limitations. Results 2186 (94%) patients with no treatment limitations discharged from ICU survived, while 142 (6%) died in hospital. 118 (61%) of patients with treatment limitations survived while 77 (39%) patients died in hospital. Patients without treatment limitations that died in hospital after ICU discharge were older, more likely to have COPD, immunocompromise or chronic renal failure, less likely to have trauma as a risk factor for ARDS. Patients that died post ICU discharge were less likely to receive neuromuscular blockade, or to receive any adjunctive measure, and had a higher pre- ICU discharge non-pulmonary SOFA score. A similar pattern was seen in patients with treatment limitations that died in hospital following ICU discharge. Conclusions A significant proportion of patients die in hospital following discharge from ICU, with higher mortality in patients with limitations of life-sustaining treatments in place. Non-survivors had higher systemic illness severity scores at ICU discharge than survivors. Trial Registration: ClinicalTrials.gov .
- Published
- 2021
30. Death in hospital following ICU discharge: insights from the LUNG SAFE study
- Author
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Madotto F., McNicholas B., Rezoagli E., Pham T., Laffey J. G., Bellani G., Pesenti A., Brochard L., Esteban A., Gattinoni L., van Haren F., Ranieri M., Rubenfeld G., Thompson B. T., Slutsky A. S., Rios F., Faruq M. O., Sottiaux T., Depuydt P., Lora F. S., Azevedo C. C., Fan E., Bugedo G., Qiu H., Gonzalez M., Silesky J., Cerny V., Nielsen J., Jibaja M., Wrigge H., Matamis D., Ranero J. L., Gomersall C., Amin P., Hashemian S. M., Clarkson K., Kurahashi K., Koh Y., Villagomez A., Zeggwagh A. A., Heunks L. M., Laake J. H., Kashif W., Synclair J., Palo J. E., do Vale Fernandes A., Sandesc D., Arabi Y., Bumbasierevic V., Nin N., Lorente J. A., Larsson A., Piquilloud L., Patjanasoontorn B., Abroug F., McAuley D. F., McNamee L., Hurtado J., Bajwa E., Dempaire G., Francois G. M., Rabboni F., Conti S., Sula H., Nunci L., Cani A., Zazu A., Dellera C., Insaurralde C. S., Alejandro R. V., Daldin J., Vinzio M., Fernandez R. O., Cardonnet L. P., Bettini L. R., Bisso M. C., Osman E. M., Setten M. G., Lovazzano P., Alvarez J., Villar V., Pozo N. C., Grubissich N., Plotnikow G. A., Vasquez D. N., Ilutovich S., Tiribelli N., Chena A., Pellegrini C. A., Saenz M. G., Estenssoro E., Brizuela M., Gianinetto H., Gomez P. E., Cerrato V. I., Bezzi M. G., Borello S. A., Loiacono F. A., Fernandez A. M., Knowles S., Reynolds C., Inskip D. M., Miller J. J., Kong J., Whitehead C., Bihari S., Seven A., Krstevski A., Rodgers H. J., Millar R. T., Mckenna T. E., Bailey I. M., Hanlon G. C., Aneman A., Lynch J. M., Azad R., Neal J., Woods P. W., Roberts B. L., Kol M. R., Wong H. S., Riss K. C., Staudinger T., Wittebole X., Berghe C., Bulpa P. A., Dive A. M., Verstraete R., Lebbinck H., Vermassen J., Meersseman P., Ceunen H., Rosa J. I., Beraldo D. O., Piras C., Rampinelli A. M., Nassar N. P., Mataloun S., Moock M., Thompson M. M., Goncalves C. H., Antonio A. C. P., Ascoli A., Biondi R. S., Fontenele D. C., Nobrega D., Sales V. M., Shindhe S., Aiman D. M., Ismail B. P. H., Laffey J., Beloncle F., Davies K. G., Cirone R., Manoharan V., Ismail M., Goligher E. C., Jassal M., Ferguson N. D., Nishikawa E., Javeed A., Curley G., Rittayamai N., Parotto M., Mehta S., Knoll J., Pronovost A., Canestrini S., Bruhn A. R., Garcia P. H., Aliaga F. A., Farias P. A., Yumha J. S., Ortiz C. A., Salas J. E., Saez A. A., Vega L. D., Labarca E. F., Martinez F. T., Carreno N. G., Lora P., Liu H., Liu L., Tang R., Luo X., An Y., Zhao H., Gao Y., Zhai Z., Ye Z. L., Wang W., Li W., Li Q., Zheng R., Yu W., Shen J., Li X., Yu T., Lu W., Wu Y. Q., Huang X. B., He Z., Lu Y., Han H., Zhang F., Sun R., Wang H. X., Qin S. H., Zhu B. H., Zhao J., Liu J., Li B., Liu J. L., Zhou F. C., Li Q. J., Zhang X. Y., Li-Xin Z., Xin-Hua Q., Jiang L., Gao Y. N., Zhao X. Y., Li Y. Y., Li X. L., Wang C., Yao Q., Yu R., Chen K., Shao H., Qin B., Huang Q. Q., Zhu W. H., Hang A. Y., Hua M. X., Li Y., Xu Y., Di Y. D., Ling L. L., Qin T. H., Wang S. H., Qin J., Han Y., Zhou S., Vargas M. P., Jimenez J. I. S., Rojas M. A. G., Solis-Quesada J. E., Ramirez-Alfaro C. M., Maca J., Sklienka P., Gjedsted J., Christiansen A., Villamagua B. G., Llano M., Burtin P., Buzancais G., Beuret P., Pelletier N., Mortaza S., Mercat A., Chelly J., Jochmans S., Terzi N., Daubin C., Carteaux G., de Prost N., Chiche J. -D., Daviaud F., Fartoukh M., Barberet G., Biehler J., Dellamonica J., Doyen D., Arnal J. -M., Briquet A., Klasen F., Papazian L., Follin A., Roux D., Messika J., Kalaitzis E., Dangers L., Combes A., Au S. -M., Beduneau G., Carpentier D., Zogheib E. H., Dupont H., Ricome S., Santoli F. L., Besset S. L., Michel P., Gelee B., Danin P. -E., Goubaux B., Crova P. J., Phan N. T., Berkelmans F., Badie J. C., Tapponnier R., Gally J., Khebbeb S., Herbrecht J. -E., Schneider F., Declercq P. -L. M., Rigaud J. -P., Duranteau J., Harrois A., Chabanne R., Marin J., Constantin J. -M., Thibault S., Ghazi M., Boukhazna M., Zein S. O., Richecoeur J. R., Combaux D. M., Grelon F., Le Moal C., Sauvadet E. P., Robine A., Lemiale V., Reuter D., Dres M., Demoule A., Goldgran-Toledano D., Baboi L., Guerin C., Lohner R., Krassler J., Schafer S., Zacharowski K. D., Meybohm P., Reske A. W., Simon P., Hopf H. -B. F., Schuetz M., Baltus T., Papanikolaou M. N., Papavasilopoulou T. G., Zacharas G. A., Ourailogloy V., Mouloudi E. K., Massa E. V., Nagy E. O., Stamou E. E., Kiourtzieva E. V., Oikonomou M. A., Avila L. E., Cortez C. A., Citalan J. E., Jog S. A., Sable S. D., Shah B., Gurjar M., Baronia A. K., Memon M., Muthuchellappan R., Ramesh V. J., Shenoy A., Unnikrishnan R., Dixit S. B., Rhayakar R. V., Ramakrishnan N., Bhardwaj V. K., Mahto H. L., Sagar S. V., Palaniswamy V., Ganesan D., Jamaati H., Heidari F., Meaney E. A., Nichol A., Knapman K. M., O'Croinin D., Dunne E. S., Breen D. M., Clarkson K. P., Jaafar R. F., Dwyer R., Amir F., Ajetunmobi O. O., O'Muircheartaigh A. C., Black C. S., Treanor N., Collins D. V., Altaf W., Zani G., Fusari M., Spadaro S., Volta C. A., Graziani R., Brunettini B., Palmese S., Formenti P., Umbrello M., Lombardo A., Pecci E., Botteri M., Savioli M., Protti A., Mattei A., Schiavoni L., Tinnirello A., Todeschini M., Giaccone P. P., Giarratano A., Cortegiani A., Sher S., Rossi A., Antonelli M. M., Montini L. M., Casalena P., Scafetti S., Panarello G., Occhipinti G., Patroniti N., Pozzi M., Biscione R. R., Poli M. M., Raimondi F., Albiero D., Crapelli G., Beck E., Pota V., Schiavone V., Molin A., Tarantino F., Monti G., Frati E., Mirabella L., Cinnella G., Fossali T., Colombo R., Pattarino P. T. I., Mojoli F., Braschi A., Borotto E. E., Cracchiolo A. N., Palma D. M., Raponi F., Foti G., Vascotto E. R., Coppadoro A., Brazzi L., Floris L., Iotti G. A., Venti A., Yamaguchi O., Takagi S., Maeyama H. N., Watanabe E., Yamaji Y., Shimizu K., Shiozaki K., Futami S., Ryosuke S., Saito K., Kameyama Y., Ueno K., Izawa M., Okuda N., Suzuki H., Harasawa T., Nasu M., Takada T., Ito F., Nunomiya S., Koyama K., Abe T., Andoh K., Kusumoto K., Hirata A., Takaba A., Kimura H., Matsumoto S., Higashijima U., Honda H., Aoki N., Imai H., Ogino Y., Mizuguchi I., Ichikado K., Nitta K., Mochizuki K., Hashida T., Tanaka H., Nakamura T., Niimi D., Ueda T., Kashiwa Y., Uchiyama A., Sabelnikovs O., Oss P., Haddad Y., Liew K. Y., Namendys-Silva S. A., Jarquin-Badiola Y. D., Sanchez-Hurtado L. A., Gomez-Flores S. S., Marin M. C., Villagomez A. J., Lemus J. S., Fierro J. M., Cervantes M. R., Mejia F. J. F., Dector D., Dector D. M., Gonzalez D. R., Estrella C. R., Sanchez-Medina J. R., Ramirez-Gutierrez A., George F. G., Aguirre J. S., Buensuseso J. A., Poblano M., University M. V., Dendane T., Balkhi H., Elkhayari M., Samkaoui N., Ezzouine H., Benslama A., Amor M., Maazouzi W., Cimic N., Beck O., Bruns M. M., Schouten J. A., Rinia M., Raaijmakers M., Van Wezel H. M., Heines S. J., Strauch U., Buise M. P., Simonis F. D., Schultz M. J., Goodson J. C., Browne T. S., Navarra L., Hunt A., Hutchison R. A., Bailey M. B., Newby L., Mcarthur C., Kalkoff M., Mcleod A., Casement J., Hacking D. J., Andersen F. H., Dolva M. S., Barratt-Due A., Noremark K. A. L., Soreide E., Sjobo B. A., Guttormsen A. B., Yoshido H. H. L., Aguilar R. Z., Oscanoa F. A. M., Alisasis A. U., Robles J. B., Pasanting-Lim R. A. B., Tan B. C., Andruszkiewicz P., Jakubowska K., Coxo C. M., Alvarez A. M., Oliveira B. S., Montanha G. M., Barros N. C., Pereira C. S., Messias A. M., Monteiro J. M., Araujo A. M., Catorze N. T., Marum S. M., Bouw M. J., Gomes R. M., Brito V. A., Castro S., Estilita J. M., Barros F. M., Serra I. M., Martinho A. M., Tomescu D. R., Marcu A., Bedreag O. H., Papurica M., Corneci D. E., Negoita S. I., Grigoriev E., Gritsan A. I., Gazenkampf A. A., Almekhlafi G., Albarrak M. M., Mustafa G. M., Maghrabi K. A., Salahuddin N., Aisa T. M., Al Jabbary A. S., Tabhan E., Arabi Y. M., Trinidad O. A., Al Dorzi H. M., Tabhan E. E., Bolon S., Smith O., Mancebo J., Aguirre-Bermeo H., Lopez-Delgado J. C., Esteve F., Rialp G., Forteza C., De Haro C., Artigas A., Albaiceta G. M., De Cima-Iglesias S., Seoane-Quiroga L., Ceniceros-Barros A., Ruiz-Aguilar A. L., Claraco-Vega L. M., Soler J. A., del Carmen Lorente M., Hermosa C., Gordo F., Prieto-Gonzalez M., Lopez-Messa J. B., Perez M. P., Perez C. P., Allue R. M., Roche-Campo F., Ibanez-Santacruz M., Temprano S., Pintado M. C., De Pablo R., Gomez P. R. A., Ruiz S. R., Moles S. I., Jurado M. ªT., Arizmendi A., Piacentini E. A., Franco N., Honrubia T., Cheng M. P., Losada E. P., Blanco J., Yuste L. J., Carbayo-Gorriz C., Cazorla-Barranquero F. G., Alonso J. G., Alda R. S., Algaba A., Navarro G., Cereijo E., Diaz-Rodriguez E., Marcos D. P., Montero L. A., Para L. H., Sanchez R. J., Navalpotro M. A. B., Abad R. D., lez R. M. G. A., Toribio D. P., Castro A. G., Artiga M. J. D., Penuelas O., Roser T. P., Olga M. F., Curto E. G., Sanchez R. M., Imma V. P., Elisabet G. M., Claverias L., Magret M., Pellicer A. M., Rodriguez L. L., Sanchez-Ballesteros J., Gonzalez-Salamanca A., Jimenez A. G., Huerta F. P., Diaz J. C. J. S., Lopez E. B., Moya D. D. L., Alfonso A. A. T., Luis P. S. E., Cesar P. S., Rafael S. I., Virgilio C. G., Recio N. N., Adamsson R. O., Rylander C. C., Holzgraefe B., Broman L. M., Wessbergh J., Persson L., Schioler F., Kedelv H., Tibblin A. O., Appelberg H., Hedlund L., Helleberg J., Eriksson K. E., Glietsch R., Larsson N., Nygren I., Nunes S. L., Morin A. -K., Kander T., Adolfsson A., Zender H. O., Leemann-Refondini C., Elatrous S., Bouchoucha S., Chouchene I., Ouanes I., Marsa L., Souissi A. B., Kamoun S., Demirkiran O., Aker M., Erbabacan E., Ceylan I., Girgin N. K., Ozcelik M., Unal N., Meco B. C., Akyol O. O., Derman S. 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J., Kitch, B. T., Cohen, J. E., Beegle, S. H., Gueret, R. M., Tulaimat, A., Choudry, S., Stigler, W., Batra, H., Huff, N. G., Lamb, K. D., Oetting, T. W., Mohr, N. M., Judy, C., Saito, S., Kheir, F. M., Kheir, F., Schlichting, A. B., Delsing, A., Crouch, D. R., Elmasri, M., Ismail, D., Dreyer, K. R., Blakeman, T. C., Baron, R. M., Grijalba, C. Q., Hou, P. C., Seethala, R., Aisiku, I., Henderson, G., Frendl, G., Hou, S. -K., Owens, R. L., Schomer, A., Bumbasirevic, V., Jovanovic, B., Surbatovic, M., Veljovic, M., UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - (MGD) Services des soins intensifs, UCL - (SLuc) Service de soins intensifs, Investigators, LUNG SAFE, Group, ESICM Trials, Madotto, F, Mcnicholas, B, Rezoagli, E, Pham, T, Laffey, J, Bellani, G, Pesenti, A, Brochard, L, Esteban, A, Gattinoni, L, van Haren, F, Ranieri, M, Rubenfeld, G, Thompson, B, Slutsky, A, Rios, F, Faruq, M, Sottiaux, T, Depuydt, P, Lora, F, Azevedo, C, Fan, E, Bugedo, G, Qiu, H, Gonzalez, M, Silesky, J, Cerny, V, Nielsen, J, Jibaja, M, Wrigge, H, Matamis, D, Ranero, J, Gomersall, C, Amin, P, Hashemian, S, Clarkson, K, Kurahashi, K, Koh, Y, Villagomez, A, Zeggwagh, A, Heunks, L, Laake, J, Kashif, W, Synclair, J, Palo, J, do Vale Fernandes, A, Sandesc, D, Arabi, Y, Bumbasierevic, V, Nin, N, Lorente, J, Larsson, A, Piquilloud, L, Patjanasoontorn, B, Abroug, F, Mcauley, D, Mcnamee, L, Hurtado, J, Bajwa, E, Dempaire, G, Francois, G, 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Vladimir Cerny, Jonas Nielsen, Manuel Jibaja, Tài Pham, Hermann Wrigge, Dimitrios Matamis, Jorge Luis Ranero, Charles Gomersall, Pravin Amin, S M Hashemian, Kevin Clarkson, Giacomo Bellani, Kiyoyasu Kurahashi, Younsuck Koh, Asisclo Villagomez, Amine Ali Zeggwagh, Leo M Heunks, Jon Henrik Laake, Waqar Kashif, Jorge Synclair, Jose Emmanuel Palo, Antero do Vale Fernandes, Dorel Sandesc, Yaasen Arabi, Vesna Bumbasierevic, Nicolas Nin, Jose A Lorente, Anders Larsson, Lise Piquilloud, Boonsong Patjanasoontorn, Fekri Abroug, Daniel F McAuley, Lia McNamee, Javier Hurtado, Ed Bajwa, Gabriel Démpaire, Guy M Francois, Francesca Rabboni, Fabiana Madotto, Sara Conti, Hektor Sula, Lordian Nunci, Alma Cani, Alan Zazu, Christian Dellera, Carolina S Insaurralde, Risso V Alejandro, Julio Daldin, Mauricio Vinzio, Ruben O Fernandez, Luis P Cardonnet, Lisandro R Bettini, Mariano Carboni Bisso, Emilio M Osman, Mariano G Setten, Pablo Lovazzano, Javier Alvarez, Veronica Villar, Norberto C Pozo, Nicolas 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Gonçalves, Ana Carolina P Antônio, Aline Ascoli, Rodrigo S Biondi, Danielle C Fontenele, Danielle Nobrega, Vanessa M Sales, Suresh Shindhe, Dk Maizatul Aiman, BPg Hj Ismail, John Laffey, Francois Beloncle, Kyle G Davies, Rob Cirone, Venika Manoharan, Mehvish Ismail, Ewan C Goligher, Mandeep Jassal, Niall D Ferguson, Erin Nishikawa, Areej Javeed, Gerard Curley, Nuttapol Rittayamai, Matteo Parotto, Sangeeta Mehta, Jenny Knoll, Antoine Pronovost, Sergio Canestrini, Alejandro R Bruhn, Patricio H Garcia, Felipe A Aliaga, Pamela A Farías, Jacob S Yumha, Claudia A Ortiz, Javier E Salas, Alejandro A Saez, Luis D Vega, Eduardo F Labarca, Felipe T Martinez, Nicolás G Carreño, Pilar Lora, Haitao Liu, Haibo Qiu, Ling Liu, Rui Tang, Xiaoming Luo, Youzhong An, Huiying Zhao, Yan Gao, Zhe Zhai, Zheng L Ye, Wei Wang, Wenwen Li, Qingdong Li, Ruiqiang Zheng, Wenkui Yu, Juanhong Shen, Xinyu Li, Tao Yu, Weihua Lu, Ya Q Wu, Xiao B Huang, Zhenyang He, Yuanhua Lu, Hui Han, Fan Zhang, Renhua Sun, Hua X Wang, 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Daniel V Collins, Wahid Altaf, Gianluca Zani, Maurizio Fusari, Savino Spadaro, Carlo A Volta, Romano Graziani, Barbara Brunettini, Salvatore Palmese, Paolo Formenti, Michele Umbrello, Andrea Lombardo, Elisabetta Pecci, Marco Botteri, Monica Savioli, Alessandro Protti, Alessia Mattei, Lorenzo Schiavoni, Andrea Tinnirello, Manuel Todeschini, Antonino Giarratano, Andrea Cortegiani, Sara Sher, Anna Rossi, Massimo M Antonelli, Luca M Montini, Paolo Casalena, Sergio Scafetti, Giovanna Panarello, Giovanna Occhipinti, Nicolò Patroniti, Matteo Pozzi, Roberto R Biscione, Michela M Poli, Ferdinando Raimondi, Daniela Albiero, Giulia Crapelli, Eduardo Beck, Vincenzo Pota, Vincenzo Schiavone, Alexandre Molin, Fabio Tarantino, Giacomo Monti, Elena Frati, Lucia Mirabella, Gilda Cinnella, Tommaso Fossali, Riccardo Colombo, Pierpaolo Terragni Ilaria Pattarino, Francesco Mojoli, Antonio Braschi, Erika E Borotto, Andrea N Cracchiolo, Daniela M Palma, Francesco Raponi, Giuseppe Foti, Ettore R Vascotto, Andrea Coppadoro, Luca Brazzi, Leda Floris, Giorgio A Iotti, Aaron Venti, Osamu Yamaguchi, Shunsuke Takagi, Hiroki N Maeyama, Eizo Watanabe, Yoshihiro Yamaji, Kazuyoshi Shimizu, Kyoko Shiozaki, Satoru Futami, Sekine Ryosuke, Koji Saito, Yoshinobu Kameyama, Keiko Ueno, Masayo Izawa, Nao Okuda, Hiroyuki Suzuki, Tomofumi Harasawa, Michitaka Nasu, Tadaaki Takada, Fumihito Ito, Shin Nunomiya, Kansuke Koyama, Toshikazu Abe, Kohkichi Andoh, Kohei Kusumoto, Akira Hirata, Akihiro Takaba, Hiroyasu Kimura, Shuhei Matsumoto, Ushio Higashijima, Hiroyuki Honda, Nobumasa Aoki, Hiroshi Imai, Yasuaki Ogino, Ichiko Mizuguchi, Kazuya Ichikado, Kenichi Nitta, Katsunori Mochizuki, Tomoaki Hashida, Hiroyuki Tanaka, Tomoyuki Nakamura, Daisuke Niimi, Takeshi Ueda, Yozo Kashiwa, Akinori Uchiyama, Olegs Sabelnikovs, Peteris Oss, Youssef Haddad, Kong Y Liew, Silvio A Ñamendys-Silva, Yves D Jarquin-Badiola, Luis A Sanchez-Hurtado, Saira S Gomez-Flores, Maria C Marin, Asisclo J Villagomez, Jordana S Lemus, Jonathan M Fierro, Mavy Ramirez Cervantes, Francisco Javier Flores Mejia, Dulce Dector, Dulce M Dector, Daniel R Gonzalez, Claudia R Estrella, Jorge R Sanchez-Medina, Alvaro Ramirez-Gutierrez, Fernando G George, Janet S Aguirre, Juan A Buensuseso, Manuel Poblano, Mohammed V University, Tarek Dendane, Amine Ali Zeggwagh, Hicham Balkhi, Mina Elkhayari, Nacer Samkaoui, Hanane Ezzouine, Abdellatif Benslama, Mourad Amor, Wajdi Maazouzi, Nedim Cimic, Oliver Beck, Monique M Bruns, Jeroen A Schouten, Myra Rinia, Monique Raaijmakers, Leo M Heunks, Hellen M Van Wezel, Serge J Heines, Ulrich Strauch, Marc P Buise, Fabienne D Simonis, Marcus J Schultz, Jennifer C Goodson, Troy S Browne, Leanlove Navarra, Anna Hunt, Robyn A Hutchison, Mathew B Bailey, Lynette Newby, Colin Mcarthur, Michael Kalkoff, Alex Mcleod, Jonathan Casement, Danielle J Hacking, Finn H Andersen, Merete S Dolva, Jon H Laake, Andreas Barratt-Due, Kim Andre L Noremark, Eldar Søreide, Brit Å Sjøbø, Anne B Guttormsen, Hector H Leon Yoshido, Ronald Zumaran Aguilar, Fredy A Montes Oscanoa, Alain U Alisasis, Joanne B Robles, Rossini Abbie B Pasanting-Lim, Beatriz C Tan, Pawel Andruszkiewicz, Karina Jakubowska, Cristina M Coxo, António M Alvarez, Bruno S Oliveira, Gustavo M Montanha, Nelson C Barros, Carlos S Pereira, António M Messias, Jorge M Monteiro, Ana M Araujo, Nuno T Catorze, Susan M Marum, Maria J Bouw, Rui M Gomes, Vania A Brito, Silvia Castro, Joana M Estilita, Filipa M Barros, Isabel M Serra, Aurelia M Martinho, Dana R Tomescu, Alexandra Marcu, Ovidiu H Bedreag, Marius Papurica, Dan E Corneci, Silvius Ioan Negoita, Evgeny Grigoriev, Alexey I Gritsan, Andrey A Gazenkampf, Ghaleb Almekhlafi, Mohamad M Albarrak, Ghanem M Mustafa, Khalid A Maghrabi, Nawal Salahuddin, Tharwat M Aisa, Ahmed S Al Jabbary, Edgardo Tabhan, Yaseen M Arabi, Olivia A Trinidad, Hasan M Al Dorzi, Edgardo E Tabhan, Stefan Bolon, Oliver Smith, Jordi Mancebo, Hernan Aguirre-Bermeo, Juan C Lopez-Delgado, Francisco Esteve, Gemma Rialp, Catalina Forteza, Candelaria De Haro, Antonio Artigas, Guillermo M Albaiceta, Sara De Cima-Iglesias, Leticia Seoane-Quiroga, Alexandra Ceniceros-Barros, Antonio L Ruiz-Aguilar, Luis M Claraco-Vega, Juan Alfonso Soler, Maria Del Carmen Lorente, Cecilia Hermosa, Federico Gordo, Miryam Prieto-González, Juan B López-Messa, Manuel P Perez, Cesar P Perez, Raquel Montoiro Allue, Ferran Roche-Campo, Marcos Ibañez-Santacruz, Susana Temprano, Maria C Pintado, Raul De Pablo, Pilar Ricart Aroa Gómez, Silvia Rodriguez Ruiz, Silvia Iglesias Moles, Mª Teresa Jurado, Alfons Arizmendi, Enrique A Piacentini, Nieves Franco, Teresa Honrubia, Meisy Perez Cheng, Elena Perez Losada, Javier Blanco, Luis J Yuste, Cecilia Carbayo-Gorriz, Francisca G Cazorla-Barranquero, Javier G Alonso, Rosa S Alda, Ángela Algaba, Gonzalo Navarro, Enrique Cereijo, Esther Diaz-Rodriguez, Diego Pastor Marcos, Laura Alvarez Montero, Luis Herrera Para, Roberto Jimenez Sanchez, Miguel Angel Blasco Navalpotro, Ricardo Diaz Abad, Raquel Montiel Gonz Á Lez, Dácil Parrilla Toribio, Alejandro G Castro, Maria Jose D Artiga, Oscar Penuelas, Tomas P Roser, Moreno F Olga, Elena Gallego Curto, Rocío Manzano Sánchez, Vallverdu P Imma, Garcia M Elisabet, Laura Claverias, Monica Magret, Ana M Pellicer, Lucia L Rodriguez, Jesús Sánchez-Ballesteros, Ángela González-Salamanca, Antonio G Jimenez, Francisco P Huerta, Juan Carlos J Sotillo Diaz, Esther Bermejo Lopez, David D Llinares Moya, Alec A Tallet Alfonso, Palazon Sanchez Eugenio Luis, Palazon Sanchez Cesar, Sánchez I Rafael, Corcoles G Virgilio, Noelia N Recio, Richard O Adamsson, Christian C Rylander, Bernhard Holzgraefe, Lars M Broman, Joanna Wessbergh, Linnea Persson, Fredrik Schiöler, Hans Kedelv, Anna Oscarsson Tibblin, Henrik Appelberg, Lars Hedlund, Johan Helleberg, Karin E Eriksson, Rita Glietsch, Niklas Larsson, Ingela Nygren, Silvia L Nunes, Anna-Karin Morin, Thomas Kander, Anne Adolfsson, Lise Piquilloud, Hervé O Zender, Corinne Leemann-Refondini, Souheil Elatrous, Slaheddine Bouchoucha, Imed Chouchene, Islem Ouanes, La Marsa, Asma Ben Souissi, Salma Kamoun, Oktay Demirkiran, Mustafa Aker, Emre Erbabacan, Ilkay Ceylan, Nermin Kelebek Girgin, Menekse Ozcelik, Necmettin Ünal, Basak Ceyda Meco, Onat O Akyol, Suleyman S Derman, Barry Kennedy, Ken Parhar, Latha Srinivasa, Lia McNamee, Danny McAuley, Phil Hopkins, Clare Mellis, Vivek Kakar, Dan Hadfield, Andre Vercueil, Kaushik Bhowmick, Sally K Humphreys, Andrew Ferguson, Raymond Mckee, Ashok S Raj, Danielle A Fawkes, Philip Watt, Linda Twohey, Rajeev R JhaMatthew Thomas, Alex Morton, Varsha Kadaba, Mark J Smith, Anil P Hormis, Santhana G Kannan, Miriam Namih, Henrik Reschreiter, Julie Camsooksai, Alek Kumar, Szabolcs Rugonfalvi, Christopher Nutt, Orla Oneill, Colette Seasman, Ged Dempsey, Christopher J Scott, Helen E Ellis, Stuart Mckechnie, Paula J Hutton, Nora N Di Tomasso, Michela N Vitale, Ruth O Griffin, Michael N Dean, Julius H Cranshaw, Emma L Willett, Nicholas Ioannou, Sarah Gillis, Peter Csabi, Rosaleen Macfadyen, Heidi Dawson, Pieter D Preez, Alexandra J Williams, Owen Boyd, Laura Ortiz-Ruiz De Gordoa, Jon Bramall, Sophie Symmonds, Simon K Chau, Tim Wenham, Tamas Szakmany, Piroska Toth-Tarsoly, Katie H Mccalman, Peter Alexander, Lorraine Stephenson, Thomas Collyer, Rhiannon Chapman, Raphael Cooper, Russell M Allan, Malcolm Sim, David W Wrathall, Donald A Irvine, Kim S Zantua, John C Adams, Andrew J Burtenshaw, Gareth P Sellors, Ingeborg D Welters, Karen E Williams, Robert J Hessell, Matthew G Oldroyd, Ceri E Battle, Suresh Pillai, Istvan Kajtor, Mageswaran Sivashanmugavel, Sinead C Okane, Adrian Donnelly, Aniko D Frigyik, Jon P Careless, Martin M May, Richard Stewart, T John Trinder, Samantha J Hagan, Matt P Wise, Jade M Cole, Caroline C MacFie, Anna T Dowling, Javier Hurtado, Nicolás Nin, Javier Hurtado, Edgardo Nuñez, Gustavo Pittini, Ruben Rodriguez, María C Imperio, Cristina Santos, Alberto Deicas, Carolina Serra, Aditya Uppalapati, Ghassan Kamel, Valerie M Banner-Goodspeed, Jeremy R Beitler, Satyanarayana Reddy Mukkera, Shreedhar Kulkarni, Jarone Lee, Tomaz Mesar, John O Shinn Iii, Dina Gomaa, Christopher Tainter, Jarone Lee, Tomaz Mesar, Jarone Lee, Dale J Yeatts, Jessica Warren, Michael J Lanspa, Russel R Miller, Colin K Grissom, Samuel M Brown, Philippe R Bauer, Ryan J Gosselin, Barrett T Kitch, Jason E Cohen, Scott H Beegle, Renaud M Gueret, Aiman Tulaimat, Shazia Choudry, William Stigler, Hitesh Batra, Nidhi G Huff, Keith D Lamb, Trevor W Oetting, Nicholas M Mohr, Claine Judy, Shigeki Saito, Fayez M Kheir, Fayez Kheir, Adam B Schlichting, Angela Delsing, Daniel R Crouch, Mary Elmasri, Daniel R Crouch, Dina Ismail, Kyle R Dreyer, Thomas C Blakeman, Kyle R Dreyer, Dina Gomaa, Rebecca M Baron, Carolina Quintana Grijalba, Peter C Hou, Raghu Seethala, Imo Aisiku, Galen Henderson, Gyorgy Frendl, Sen-Kuang Hou, Robert L Owens, Ashley Schomer, Vesna Bumbasirevic, Bojan Jovanovic, Maja Surbatovic, Milic Veljovic, John G Laffey, Giacomo Bellani, Antonio Pesenti
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Male ,ARDS ,LUNG SAFE ,health care facilities, manpower, and services ,Acute hypoxemic respiratory failure ,Acute respiratory distress syndrome ,Hospital survival ,ICU discharge ,Kaplan-Meier Estimate ,Critical Care and Intensive Care Medicine ,0302 clinical medicine ,Risk Factors ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,COPD ,Medical emergencies. Critical care. Intensive care. First aid ,Middle Aged ,Patient Discharge ,Intensive Care Units ,medicine.anatomical_structure ,Lung safe ,SOFA score ,Female ,Respiratory Insufficiency ,Adult ,medicine.medical_specialty ,NO ,03 medical and health sciences ,Settore MED/41 - ANESTESIOLOGIA ,medicine ,Humans ,ddc:610 ,Risk factor ,Mortality ,Aged ,Lung ,RC86-88.9 ,business.industry ,Research ,030208 emergency & critical care medicine ,medicine.disease ,Logistic Models ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,Respiratory failure ,Emergency medicine ,Observational study ,business - Abstract
Background To determine the frequency of, and factors associated with, death in hospital following ICU discharge to the ward. Methods The Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE study was an international, multicenter, prospective cohort study of patients with severe respiratory failure, conducted across 459 ICUs from 50 countries globally. This study aimed to understand the frequency and factors associated with death in hospital in patients who survived their ICU stay. We examined outcomes in the subpopulation discharged with no limitations of life sustaining treatments (‘treatment limitations’), and the subpopulations with treatment limitations. Results 2186 (94%) patients with no treatment limitations discharged from ICU survived, while 142 (6%) died in hospital. 118 (61%) of patients with treatment limitations survived while 77 (39%) patients died in hospital. Patients without treatment limitations that died in hospital after ICU discharge were older, more likely to have COPD, immunocompromise or chronic renal failure, less likely to have trauma as a risk factor for ARDS. Patients that died post ICU discharge were less likely to receive neuromuscular blockade, or to receive any adjunctive measure, and had a higher pre- ICU discharge non-pulmonary SOFA score. A similar pattern was seen in patients with treatment limitations that died in hospital following ICU discharge. Conclusions A significant proportion of patients die in hospital following discharge from ICU, with higher mortality in patients with limitations of life-sustaining treatments in place. Non-survivors had higher systemic illness severity scores at ICU discharge than survivors. Trial Registration: ClinicalTrials.gov NCT02010073.
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- 2021
31. Antifungal Evaluation of Zn and Zn-Cu Oxychloride Nanoparticles.
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Hermida-Montero, L A, primary, Ruiz-Leyva, IC, additional, Paraguay-Delgado, F, additional, Lardizábal-Gutiérrez, D, additional, Muñoz-Castellanos, LN, additional, and Villalba-Bejarano, CV, additional
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- 2022
- Full Text
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32. Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: Insights from the LUNG SAFE study
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D., Penuelas O., Roser T. P., Olga M. F., Curto E. G., Sanchez R. M., Imma V. P., Elisabet G. M., Claverias L., Magret M., Pellicer A. M., Rodriguez L. L., Sanchez-Ballesteros J., Gonzalez-Salamanca A., Jimenez A. G., Huerta F. P., Sotillo Diaz J. C. J., Lopez E. B., Llinares Moya D. D., Tallet Alfonso A. A., Luis P. S. E., Cesar P. S., Rafael S. I., Virgilio C. G., Recio N. N., Adamsson R. O., Rylander C. C., Holzgraefe B., Broman L. M., Wessbergh J., Persson L., Schioler F., Kedelv H., Tibblin A. O., Appelberg H., Hedlund L., Helleberg J., Eriksson K. E., Glietsch R., Larsson N., Nygren I., Nunes S. L., Morin A. -K., Kander T., Adolfsson A., Zender H. O., Leemann-Refondini C., Elatrous S., Bouchoucha S., Chouchene I., Ouanes I., Souissi A. B., Kamoun S., Demirkiran O., Aker M., Erbabacan E., Ceylan I., Girgin N. K., Ozcelik M., Unal N., Meco B. C., Akyol O. O., Derman S. S., Kennedy B., Parhar K., Srinivasa L., McAuley D., Hopkins P., Mellis C., Kakar V., Hadfield D., Vercueil A., Bhowmick K., Humphreys S. K., Ferguson A., McKee R., Raj A. S., Fawkes D. A., Watt P., Twohey L., Jhamatthew Thomas R. R., Morton A., Kadaba V., Smith M. J., Hormis A. P., Kannan S. G., Namih M., Reschreiter H., Camsooksai J., Kumar A., Rugonfalvi S., Nutt C., O'Neill O., Seasman C., Dempsey G., Scott C. J., Ellis H. E., McKechnie S., Hutton P. J., Di Tomasso N. N., Vitale M. N., Griffin R. O., Dean M. N., Cranshaw J. H., Willett E. L., Ioannou N., Gillis S., Csabi P., MacFadyen R., Dawson H., Preez P. D., Williams A. J., Boyd O., De Gordoa L. O. -R., Bramall J., Symmonds S., Chau S. K., Wenham T., Szakmany T., Toth-Tarsoly P., McCalman K. H., Alexander P., Stephenson L., Collyer T., Chapman R., Cooper R., Allan R. M., Sim M., Wrathall D. W., Irvine D. A., Zantua K. S., Adams J. C., Burtenshaw A. J., Sellors G. P., Welters I. D., Williams K. E., Hessell R. J., Oldroyd M. G., Battle C. E., Pillai S., Kajtor I., Sivashanmugavel M., O'Kane S. C., Donnelly A., Frigyik A. D., Careless J. P., May M. M., Stewart R., Trinder T. J., Hagan S. J., Wise M. P., Cole J. M., MacFie C. C., Dowling A. T., Nunez E., Pittini G., Rodriguez R., Imperio M. C., Santos C., Franca A. G., Ebeid A., Deicas A., Serra C., Uppalapati A., Kamel G., Banner-Goodspeed V. M., Beitler J. R., Mukkera S. R., Kulkarni S., Lee J., Mesar T., Shinn J. O., Gomaa D., Tainter C., Yeatts D. J., Warren J., Lanspa M. J., Miller R. R., Grissom C. K., Brown S. M., Bauer P. R., Gosselin R. J., Kitch B. T., Cohen J. E., Beegle S. H., Gueret R. M., Tulaimat A., Choudry S., Stigler W., Batra H., Huff N. G., Lamb K. D., Oetting T. W., Mohr N. M., Judy C., Saito S., Kheir F. M., Kheir F., Schlichting A. B., Delsing A., Crouch D. R., Elmasri M., Ismail D., Dreyer K. R., Blakeman T. C., Baron R. M., Grijalba C. Q., Hou P. C., Seethala R., Aisiku I., Henderson G., Frendl G., Hou S. -K., Owens R. L., Schomer A., Bumbasirevic V., Jovanovic B., Surbatovic M., and Veljovic M.
- Abstract
Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073
- Published
- 2020
33. First approach to ageing the cuttlefish Sepia bertheloti. Comparison of growth in two fishing areas
- Author
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Guerra Marrero, A., Bartolomé-Baraza, A. (Aurora), Jiménez Alvarado, D., Couce Montero, L., Espino Ruano, A., Catro, J.J., and Perales-Raya, C. (Catalina)
- Subjects
age ,growth ,aging ,cephalopods ,sepia - Published
- 2022
34. Effects of isotropic and anisotropic turbulent structures over spray atomization in the near field
- Author
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Crialesi-Esposito, Marco, Gonzalez-Montero, L. A., Salvador, F. J., Crialesi-Esposito, Marco, Gonzalez-Montero, L. A., and Salvador, F. J.
- Abstract
Sprays and atomization processes are extremely diffused both in nature and in industrial applications. In this paper we analyze the influence of the nozzle turbulence on primary atomization, focusing on the resulting turbulent field and atomization patterns in the Near Field (NF). In order to do so, a Synthetic Boundary Condition (SBC) and a Mapped Boundary Condition (MBC), producing respectively isotropic and anisotropic turbulent fields, have been generated as inflow conditions for the spray Direct Numerical Simulations (DNS). We present a specific methodology to ensure consistency on turbulence intensity and integral lengthscale between the two inflows. The analysis performed on the turbulent field (using one-point statistics and spectrum analysis) reveals a significantly stronger turbulent field generated by the inflow boundary conditions with anisotropic structures. While the increased turbulence field generated in the MBC case results in a higher number of droplets generated, the probability functions of both cases are extremely similar, leading to the non-obvious conclusion that the atomization patterns are only slightly affected by the inflow condition. These considerations are supported by the analysis of droplet size distributions, radial distribution functions, axial and radial distributions, highlighting extremely similar behaviors between the MBC and the SBC cases. Finally, these analyses and their computations are presented in detail, underlining how this type of point-process characterization shows interesting potential in future studies on sprays., QC 20220523
- Published
- 2022
- Full Text
- View/download PDF
35. Age validation of Sepia officinalis in early stages using beaks
- Author
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Guerra Marrero, A., Jimenez Alvarado, D., Lishchenko, F., Couce Montero, L., Espino Ruano, A., Catro, J.J., Perales-Raya, Catalina, Guerra Marrero, A., Jimenez Alvarado, D., Lishchenko, F., Couce Montero, L., Espino Ruano, A., Catro, J.J., and Perales-Raya, Catalina
- Published
- 2022
36. Age validation in early stages of Sepia officinalis and its application to age estimation of Sepia species
- Author
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Guerra-Marrero, A., Couce-Montero, L., Espino-Ruano, A., Jimenez-Alvarado, D., Castro, J.J., Perales-Raya, Catalina, Guerra-Marrero, A., Couce-Montero, L., Espino-Ruano, A., Jimenez-Alvarado, D., Castro, J.J., and Perales-Raya, Catalina
- Published
- 2022
37. Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study
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L., Ioannou, N., Gillis, S., Csabi, P., Macfadyen, R., Dawson, H., Preez, P. D., Williams, A. J., Boyd, O., De Gordoa, L. O. -R., Bramall, J., Symmonds, S., Chau, S. K., Wenham, T., Szakmany, T., Toth-Tarsoly, P., McCalman, K. H., Alexander, P., Stephenson, L., Collyer, T., Chapman, R., Cooper, R., Allan, R. M., Sim, M., Wrathall, D. W., Irvine, D. A., Zantua, K. S., Adams, J. C., Burtenshaw, A. J., Sellors, G. P., Welters, I. D., Williams, K. E., Hessell, R. J., Oldroyd, M. G., Battle, C. E., Pillai, S., Kajtor, I., Sivashanmugavel, M., O’Kane, S. C., Donnelly, A., Frigyik, A. D., Careless, J. P., May, M. M., Stewart, R., Trinder, T. J., Hagan, S. J., Wise, M. P., Cole, J. M., MacFie, C. C., Dowling, A. T., Nuñez, E., Pittini, G., Rodriguez, R., Imperio, M. C., Santos, C., França, A. G., Ebeid, A., Deicas, A., Serra, C., Uppalapati, A., Kamel, G., Banner-Goodspeed, V. M., Beitler, J. R., Mukkera, S. R., Kulkarni, S., Lee, J., Mesar, T., Shinn, J. 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L., Schomer, A., Bumbasirevic, V., Jovanovic, B., Surbatovic, M., Veljovic, M., LUNG SAFE Investigators and the ESICM Trials Group, Madotto, F., Pham, T., Bellani, G., Bos, L.D., Simonis, F.D., Fan, E., Artigas, A., Brochard, L., Schultz, M.J., Laffey, J.G., Pesenti, A., Esteban, A., Gattinoni, L., van Haren, F., Larsson, A., McAuley, D.F., Ranieri, M., Rubenfeld, G., Thompson, B.T., Wrigge, H., Slutsky, A.S., Rios, F., Van Haren, F., Sottiaux, T., Depuydt, P., Lora, F.S., Azevedo, L.C., Bugedo, G., Qiu, H., Gonzalez, M., Silesky, J., Cerny, V., Nielsen, J., Jibaja, M., Matamis, D., Ranero, J.L., Amin, P., Hashemian, S.M., Clarkson, K., Kurahashi, K., Villagomez, A., Zeggwagh, A.A., Heunks, L.M., Laake, J.H., Palo, J.E., do Vale Fernandes, A., Sandesc, D., Arabi, Y., Bumbasierevic, V., Nin, N., Lorente, J.A., Piquilloud, L., Abroug, F., McNamee, L., Hurtado, J., Bajwa, E., Démpaire, G., Sula, H., Nunci, L., Cani, A., Zazu, A., Dellera, C., Alejandro, R.V., Daldin, J., Vinzio, M., 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Schomer, A., Bumbasirevic, V., Jovanovic, B., Surbatovic, M., Veljovic, M., LUNG SAFE Investigators and the ESICM Trials Group, Madotto, F, Pham, T, Bellani, G, Bos, L, Simonis, F, Fan, E, Artigas, A, Brochard, L, Schultz, M, Laffey, J, Pesenti, A, Esteban, A, Gattinoni, L, van Haren, F, Larsson, A, Mcauley, D, Ranieri, M, Rubenfeld, G, Thompson, B, Wrigge, H, Slutsky, A, Rios, F, Sottiaux, T, Depuydt, P, Lora, F, Azevedo, L, Bugedo, G, Qiu, H, Gonzalez, M, Silesky, J, Cerny, V, Nielsen, J, Jibaja, M, Matamis, D, Ranero, J, Amin, P, Hashemian, S, Clarkson, K, Kurahashi, K, Villagomez, A, Zeggwagh, A, Heunks, L, Laake, J, Palo, J, Do Vale Fernandes, A, Sandesc, D, Arabi, Y, Bumbasierevic, V, Nin, N, Lorente, J, Piquilloud, L, Abroug, F, Mcnamee, L, Hurtado, J, Bajwa, E, Démpaire, G, Sula, H, Nunci, L, Cani, A, Zazu, A, Dellera, C, Alejandro, R, Daldin, J, Vinzio, M, Fernandez, R, Cardonnet, L, Bettini, L, Bisso, M, Osman, E, Setten, M, Lovazzano, P, Alvarez, J, Villar, V, Pozo, N, Grubissich, N, Plotnikow, G, Vasquez, D, Ilutovich, S, Tiribelli, N, Chena, A, Pellegrini, C, Saenz, M, Estenssoro, E, Brizuela, M, Gianinetto, H, Gomez, P, Cerrato, V, Bezzi, M, Borello, S, Loiacono, F, Fernandez, A, Knowles, S, Reynolds, C, Inskip, D, Miller, J, Kong, J, Whitehead, C, Bihari, S, Seven, A, Krstevski, A, Rodgers, H, Millar, R, Mckenna, T, Bailey, I, Hanlon, G, Aneman, A, Lynch, J, Azad, R, Neal, J, Woods, P, Roberts, B, Kol, M, Wong, H, Riss, K, Staudinger, T, Wittebole, X, Berghe, C, Bulpa, P, Dive, A, Verstraete, R, Lebbinck, H, Vermassen, J, Meersseman, P, Ceunen, H, Rosa, J, Beraldo, D, Piras, C, Rampinelli, A, Nassar, A, Mataloun, S, Moock, M, Thompson, M, Gonçalves, C, Antônio, A, Ascoli, A, Biondi, R, Fontenele, D, Nobrega, D, Sales, V, Shindhe, S, Ismail, D, Beloncle, F, Davies, K, Cirone, R, Manoharan, V, Ismail, M, Goligher, E, Jassal, M, Nishikawa, E, Javeed, A, Curley, G, Rittayamai, N, Parotto, M, Ferguson, N, Mehta, S, Knoll, J, Pronovost, A, Canestrini, S, Bruhn, A, Garcia, P, Aliaga, F, Farías, P, Yumha, J, Ortiz, C, Salas, J, Saez, A, Vega, L, Labarca, E, Martinez, F, Carreño, N, Lora, P, Liu, H, Liu, L, Tang, R, Luo, X, An, Y, Zhao, H, Gao, Y, Zhai, Z, Ye, Z, Wang, W, Li, W, Li, Q, Zheng, R, Yu, W, Shen, J, Li, X, Yu, T, Lu, W, Wu, Y, Huang, X, He, Z, Lu, Y, Han, H, Zhang, F, Sun, R, Wang, H, Qin, S, Zhu, B, Zhao, J, Liu, J, Li, B, Zhou, F, Zhang, X, Li-Xin, Z, Xin-Hua, Q, Jiang, L, Zhao, X, Li, Y, Wang, C, Yao, Q, Yu, R, Chen, K, Shao, H, Qin, B, Huang, Q, Zhu, W, Hang, A, Hua, M, Xu, Y, Di, Y, Ling, L, Qin, T, Wang, S, Qin, J, Han, Y, Zhou, S, Vargas, M, Jimenez, J, Rojas, M, Solis-Quesada, J, Ramirez-Alfaro, C, Máca, J, Sklienka, P, Gjedsted, J, Christiansen, A, Villamagua, B, Llano, M, Burtin, P, Buzancais, G, Beuret, P, Pelletier, N, Mortaza, S, Mercat, A, Chelly, J, Jochmans, S, Terzi, N, Daubin, C, Carteaux, G, de Prost, N, Chiche, J, Daviaud, F, Fartoukh, M, Barberet, G, Biehler, J, Dellamonica, J, Doyen, D, Arnal, J, Briquet, A, Hraiech, S, Papazian, L, Roux, D, Messika, J, Kalaitzis, E, Dangers, L, Combes, A, Au, S, Béduneau, G, Carpentier, D, Zogheib, E, Dupont, H, Ricome, S, Santoli, F, Besset, S, Michel, P, Gelée, B, Danin, P, Goubaux, B, Crova, P, Phan, N, Berkelmans, F, Badie, J, Tapponnier, R, Gally, J, Khebbeb, S, Herbrecht, J, Schneider, F, Declercq, P, Rigaud, J, Duranteau, J, Harrois, A, Chabanne, R, Marin, J, Bigot, C, Thibault, S, Ghazi, M, Boukhazna, M, Zein, S, Richecoeur, J, Combaux, D, Grelon, F, Le Moal, C, Sauvadet, E, Robine, A, Lemiale, V, Reuter, D, Dres, M, Demoule, A, Goldgran-Toledano, D, Baboi, L, Guérin, C, Lohner, R, Kraßler, J, Schäfer, S, Zacharowski, K, Meybohm, P, Reske, A, Simon, P, Hopf, H, Schuetz, M, Baltus, T, Papanikolaou, M, Papavasilopoulou, T, Zacharas, G, Ourailogloy, V, Mouloudi, E, Massa, E, Nagy, E, Stamou, E, Kiourtzieva, E, Oikonomou, M, Avila, L, Cortez, C, Citalán, J, Jog, S, Sable, S, Shah, B, Gurjar, M, Baronia, A, Memon, M, Muthuchellappan, R, Ramesh, V, Shenoy, A, Unnikrishnan, R, Dixit, S, Rhayakar, R, Ramakrishnan, N, Bhardwaj, V, Mahto, H, Sagar, S, Palaniswamy, V, Ganesan, D, Jamaati, H, Heidari, F, Meaney, E, Nichol, A, Knapman, K, O’Croinin, D, Dunne, E, Breen, D, Jaafar, R, Dwyer, R, Amir, F, Ajetunmobi, O, O’Muircheartaigh, A, Black, C, Treanor, N, Collins, D, Altaf, W, Zani, G, Fusari, M, Spadaro, S, Volta, C, Graziani, R, Brunettini, B, Palmese, S, Formenti, P, Umbrello, M, Lombardo, A, Pecci, E, Botteri, M, Savioli, M, Protti, A, Mattei, A, Schiavoni, L, Tinnirello, A, Todeschini, M, Giarratano, A, Cortegiani, A, Sher, S, Rossi, A, Antonelli, M, Montini, L, Casalena, P, Scafetti, S, Panarello, G, Occhipinti, G, Patroniti, N, Pozzi, M, Biscione, R, Poli, M, Raimondi, F, Albiero, D, Crapelli, G, Beck, E, Pota, V, Schiavone, V, Molin, A, Tarantino, F, Monti, G, Frati, E, Mirabella, L, Cinnella, G, Fossali, T, Colombo, R, Pattarino, P, Mojoli, F, Braschi, A, Borotto, E, Cracchiolo, A, Palma, D, Raponi, F, Foti, G, Vascotto, E, Coppadoro, A, Brazzi, L, Floris, L, Iotti, G, Venti, A, Yamaguchi, O, Takagi, S, Maeyama, H, Watanabe, E, Yamaji, Y, Shimizu, K, Shiozaki, K, Futami, S, Ryosuke, S, Saito, K, Kameyama, Y, Ueno, K, Izawa, M, Okuda, N, Suzuki, H, Harasawa, T, Nasu, M, Takada, T, Ito, F, Nunomiya, S, Koyama, K, Abe, T, Andoh, K, Kusumoto, K, Hirata, A, Takaba, A, Kimura, H, Matsumoto, S, Higashijima, U, Honda, H, Aoki, N, Imai, H, Ogino, Y, Mizuguchi, I, Ichikado, K, Nitta, K, Mochizuki, K, Hashida, T, Tanaka, H, Nakamura, T, Niimi, D, Ueda, T, Kashiwa, Y, Uchiyama, A, Sabelnikovs, O, Oss, P, Haddad, Y, Liew, K, Ñamendys-Silva, S, Jarquin-Badiola, Y, Sanchez-Hurtado, L, Gomez-Flores, S, Marin, M, Lemus, J, Fierro, J, Cervantes, M, Mejia, F, Dector, D, Gonzalez, D, Estrella, C, Sanchez-Medina, J, Ramirez-Gutierrez, A, George, F, Aguirre, J, Buensuseso, J, Poblano, M, Dendane, T, Balkhi, H, Elkhayari, M, Samkaoui, N, Ezzouine, H, Benslama, A, Amor, M, Maazouzi, W, Cimic, N, Beck, O, Bruns, M, Schouten, J, Rinia, M, Raaijmakers, M, van Wezel, H, Heines, S, Strauch, U, Buise, M, Goodson, J, Browne, T, Navarra, L, Hunt, A, Hutchison, R, Bailey, M, Newby, L, Mcarthur, C, Kalkoff, M, Mcleod, A, Casement, J, Hacking, D, Andersen, F, Dolva, M, Barratt-Due, A, Noremark, K, Søreide, E, Sjøbø, B, Guttormsen, A, Yoshido, H, Aguilar, R, Oscanoa, F, Alisasis, A, Robles, J, Pasanting-Lim, R, Tan, B, Andruszkiewicz, P, Jakubowska, K, Coxo, C, Alvarez, A, Oliveira, B, Montanha, G, Barros, N, Pereira, C, Messias, A, Monteiro, J, Araujo, A, Catorze, N, Marum, S, Bouw, M, Gomes, R, Brito, V, Castro, S, Estilita, J, Barros, F, Serra, I, Martinho, A, Tomescu, D, Marcu, A, Bedreag, O, Papurica, M, Corneci, D, Negoita, S, Grigoriev, E, Gritsan, A, Gazenkampf, A, Almekhlafi, G, Albarrak, M, Mustafa, G, Maghrabi, K, Salahuddin, N, Aisa, T, Jabbary, A, Tabhan, E, Trinidad, O, Dorzi, H, Bolon, S, Smith, O, Mancebo, J, Aguirre-Bermeo, H, Lopez-Delgado, J, Esteve, F, Rialp, G, Forteza, C, de Haro, C, Albaiceta, G, de Cima-Iglesias, S, Seoane-Quiroga, L, Ceniceros-Barros, A, Ruiz-Aguilar, A, Claraco-Vega, L, Soler, J, Del Carmen Lorente, M, Hermosa, C, Gordo, F, Prieto-González, M, López-Messa, J, Perez, M, Perez, C, Allue, R, Roche-Campo, F, Ibañez-Santacruz, M, Temprano, S, Pintado, M, de Pablo, R, Gómez, P, Ruiz, S, Moles, S, Jurado, M, Arizmendi, A, Piacentini, E, Franco, N, Honrubia, T, Cheng, M, Losada, E, Blanco, J, Yuste, L, Carbayo-Gorriz, C, Cazorla-Barranquero, F, Alonso, J, Alda, R, Algaba, Á, Navarro, G, Cereijo, E, Diaz-Rodriguez, E, Marcos, D, Montero, L, Para, L, Sanchez, R, Navalpotro, M, Abad, R, González, R, Toribio, D, Castro, A, Artiga, M, Penuelas, O, Roser, T, Olga, M, Curto, E, Sánchez, R, Imma, V, Elisabet, G, Claverias, L, Magret, M, Pellicer, A, Rodriguez, L, Sánchez-Ballesteros, J, González-Salamanca, Á, Jimenez, A, Huerta, F, Diaz, J, Lopez, E, Moya, D, Alfonso, A, Luis, P, Cesar, P, Rafael, S, Virgilio, C, Recio, N, Adamsson, R, Rylander, C, Holzgraefe, B, Broman, L, Wessbergh, J, Persson, L, Schiöler, F, Kedelv, H, Tibblin, A, Appelberg, H, Hedlund, L, Helleberg, J, Eriksson, K, Glietsch, R, Larsson, N, Nygren, I, Nunes, S, Morin, A, Kander, T, Adolfsson, A, Zender, H, Leemann-Refondini, C, Elatrous, S, Bouchoucha, S, Chouchene, I, Ouanes, I, Souissi, A, Kamoun, S, Demirkiran, O, Aker, M, Erbabacan, E, Ceylan, I, Girgin, N, Ozcelik, M, Ünal, N, Meco, B, Akyol, O, Derman, S, Kennedy, B, Parhar, K, Srinivasa, L, Hopkins, P, Mellis, C, Kakar, V, Hadfield, D, Vercueil, A, Bhowmick, K, Humphreys, S, Ferguson, A, Mckee, R, Raj, A, Fawkes, D, Watt, P, Twohey, L, Thomas, R, Morton, A, Kadaba, V, Smith, M, Hormis, A, Kannan, S, Namih, M, Reschreiter, H, Camsooksai, J, Kumar, A, Rugonfalvi, S, Nutt, C, O’Neill, O, Seasman, C, Dempsey, G, Scott, C, Ellis, H, Mckechnie, S, Hutton, P, Di Tomasso, N, Vitale, M, Griffin, R, Dean, M, Cranshaw, J, Willett, E, Ioannou, N, Gillis, S, Csabi, P, Macfadyen, R, Dawson, H, Preez, P, Williams, A, Boyd, O, de Gordoa, L, Bramall, J, Symmonds, S, Chau, S, Wenham, T, Szakmany, T, Toth-Tarsoly, P, Mccalman, K, Alexander, P, Stephenson, L, Collyer, T, Chapman, R, Cooper, R, Allan, R, Sim, M, Wrathall, D, Irvine, D, Zantua, K, Adams, J, Burtenshaw, A, Sellors, G, Welters, I, Williams, K, Hessell, R, Oldroyd, M, Battle, C, Pillai, S, Kajtor, I, Sivashanmugavel, M, O’Kane, S, Donnelly, A, Frigyik, A, Careless, J, May, M, Stewart, R, Trinder, T, Hagan, S, Wise, M, Cole, J, Macfie, C, Dowling, A, Nuñez, E, Pittini, G, Rodriguez, R, Imperio, M, Santos, C, França, A, Ebeid, A, Deicas, A, Serra, C, Uppalapati, A, Kamel, G, Banner-Goodspeed, V, Beitler, J, Mukkera, S, Kulkarni, S, Lee, J, Mesar, T, Shinn, J, Gomaa, D, Tainter, C, Yeatts, D, Warren, J, Lanspa, M, Miller, R, Grissom, C, Brown, S, Bauer, P, Gosselin, R, Kitch, B, Cohen, J, Beegle, S, Gueret, R, Tulaimat, A, Choudry, S, Stigler, W, Batra, H, Huff, N, Lamb, K, Oetting, T, Mohr, N, Judy, C, Saito, S, Kheir, F, Schlichting, A, Delsing, A, Crouch, D, Elmasri, M, Dreyer, K, Blakeman, T, Baron, R, Grijalba, C, Hou, P, Seethala, R, Aisiku, I, Henderson, G, Frendl, G, Hou, S, Owens, R, Schomer, A, Bumbasirevic, V, Jovanovic, B, Surbatovic, M, Veljovic, M, Madotto, Fabiana, Pham, Tài, Bellani, Giacomo, Bos, Lieuwe D., Simonis, Fabienne D., Fan, Eddy, Artigas, Antonio, Brochard, Laurent, Schultz, Marcus J., Laffey, John G., Pesenti, Antonio, Esteban, Andre, Gattinoni, Luciano, van Haren, Frank, Larsson, Ander, McAuley, Daniel F., Ranieri, Marco, Rubenfeld, Gordon, Thompson, B. Taylor, Wrigge, Hermann, Slutsky, Arthur S., Rios, Fernando, Lora, Fredy S., Azevedo, Luciano Cesar, Bugedo, Guillermo, Qiu, Haibo, Gonzalez, Marco, Silesky, Juan, Cerny, Vladimir, Nielsen, Jona, Jibaja, Manuel, Matamis, Dimitrio, Ranero, Jorge Lui, Amin, Pravin, Clarkson, Kevin, Kurahashi, Kiyoyasu, Villagomez, Asisclo, Zeggwagh, Amine Ali, Heunks, Leo M., Laake, Jon Henrik, Palo, Jose Emmanuel, Do Vale Fernandes, Antero, Sandesc, Dorel, Arabi, Yaasen, Bumbasierevic, Vesna, Nin, Nicola, Lorente, Jose A., Piquilloud, Lise, Abroug, Fekri, McNamee, Lia, Hurtado, Javier, Bajwa, Ed, Démpaire, Gabriel, Sula, Hektor, Nunci, Lordian, Cani, Alma, Zazu, Alan, Dellera, Christian, Alejandro, Risso V., Daldin, Julio, Vinzio, Mauricio, Fernandez, Ruben O., Cardonnet, Luis P., Bettini, Lisandro R., Bisso, Mariano Carboni, Osman, Emilio M., Setten, Mariano G., Lovazzano, Pablo, Alvarez, Javier, Villar, Veronica, Pozo, Norberto C., Grubissich, Nicola, Plotnikow, Gustavo A., Vasquez, Daniela N., Ilutovich, Santiago, Tiribelli, Norberto, Chena, Ariel, Pellegrini, Carlos A., Saenz, María G., Estenssoro, Elisa, Brizuela, Matia, Gianinetto, Hernan, Gomez, Pablo E., Cerrato, Valeria I., Bezzi, Marco G., Borello, Silvina A., Loiacono, Flavia A., Fernandez, Adriana M., Knowles, Serena, Reynolds, Claire, Inskip, Deborah M., Miller, Jennene J., Kong, Jing, Whitehead, Christina, Bihari, Shailesh, Seven, Aylin, Krstevski, Amanda, Rodgers, Helen J., Millar, Rebecca T., Mckenna, Toni E., Bailey, Irene M., Hanlon, Gabrielle C., Aneman, Ander, Lynch, Joan M., Azad, Raman, Neal, John, Woods, Paul W., Roberts, Brigit L., Kol, Mark R., Wong, Helen S., Riss, Katharina C., Staudinger, Thoma, Wittebole, Xavier, Berghe, Caroline, Bulpa, Pierre A., Dive, Alain M., Verstraete, Rik, Lebbinck, Herve, Depuydt, Pieter, Vermassen, Jori, Meersseman, Philippe, Ceunen, Helga, Rosa, Jonas I., Beraldo, Daniel O., Piras, Claudio, Rampinelli, Adenilton M., Nassar, Antonio P., Mataloun, Sergio, Moock, Marcelo, Thompson, Marlus M., Gonçalves, Claudio H., Antônio, Ana Carolina P., Ascoli, Aline, Biondi, Rodrigo S., Fontenele, Danielle C., Nobrega, Danielle, Sales, Vanessa M., Shindhe, Suresh, Ismail, Dk Maizatul Aiman B. Pg Hj, Laffey, John, Beloncle, Francoi, Davies, Kyle G., Cirone, Rob, Manoharan, Venika, Ismail, Mehvish, Goligher, Ewan C., Jassal, Mandeep, Nishikawa, Erin, Javeed, Areej, Curley, Gerard, Rittayamai, Nuttapol, Parotto, Matteo, Ferguson, Niall D., Mehta, Sangeeta, Knoll, Jenny, Pronovost, Antoine, Canestrini, Sergio, Bruhn, Alejandro R., Garcia, Patricio H., Aliaga, Felipe A., Farías, Pamela A., Yumha, Jacob S., Ortiz, Claudia A., Salas, Javier E., Saez, Alejandro A., Vega, Luis D., Labarca, Eduardo F., Martinez, Felipe T., Carreño, Nicolás G., Lora, Pilar, Liu, Haitao, Liu, Ling, Tang, Rui, Luo, Xiaoming, An, Youzhong, Zhao, Huiying, Gao, Yan, Zhai, Zhe, Ye, Zheng L., Wang, Wei, Li, Wenwen, Li, Qingdong, Zheng, Ruiqiang, Yu, Wenkui, Shen, Juanhong, Li, Xinyu, Yu, Tao, Lu, Weihua, Wu, Ya, Huang, Xiao B., He, Zhenyang, Lu, Yuanhua, Han, Hui, Zhang, Fan, Sun, Renhua, Wang, Hua X., Qin, Shu H., Zhu, Bao H., Zhao, Jun, Liu, Jian, Li, Bin, Liu, Jing L., Zhou, Fa, Li, Qiong J., Zhang, Xing Y., Li-Xin, Zhou, Xin-Hua, Qiang, Jiang, Liangyan, Gao, Yuan N., Zhao, Xian Y., Li, Yuan Y., Li, Xiao L., Wang, Chunting, Yao, Qingchun, Yu, Rongguo, Chen, Kai, Shao, Huanzhang, Qin, Bingyu, Huang, Qing Q., Zhu, Wei H., Hang, Ai, Hua, Ma, Li, Yimin, Xu, Yonghao, Di, Yu, Ling, Long L., Qin, Tie H., Wang, Shou H., Qin, Junping, Han, Yi, Zhou, Suming, Vargas, Monica P., Jimenez, Juan I. Silesky, Rojas, Manuel A. González, Solis-Quesada, Jaime E., Ramirez-Alfaro, Christian M., Máca, Jan, Sklienka, Peter, Gjedsted, Jakob, Christiansen, Aage, Villamagua, Boris G., Llano, Miguel, Burtin, Philippe, Buzancais, Gautier, Beuret, Pascal, Pelletier, Nicola, Mortaza, Satar, Mercat, Alain, Chelly, Jonathan, Jochmans, Sébastien, Terzi, Nicola, Daubin, Cédric, Carteaux, Guillaume, de Prost, Nicola, Chiche, Jean-Daniel, Daviaud, Fabrice, Pham, Tai, Fartoukh, Muriel, Barberet, Guillaume, Biehler, Jerome, Dellamonica, Jean, Doyen, Deni, Arnal, Jean-Michel, Briquet, Anai, Hraiech, Sami, Papazian, Laurent, Roux, Damien, Messika, Jonathan, Kalaitzis, Evangelo, Dangers, Laurence, Combes, Alain, Au, Siu-Ming, Béduneau, Gaetan, Carpentier, Dorothée, Zogheib, Elie H., Dupont, Herve, Ricome, Sylvie, Santoli, Francesco L., Besset, Sebastien L., Michel, Philippe, Gelée, Bruno, Danin, Pierre-Eric, Goubaux, Bernard, Crova, Philippe J., Phan, Nga T., Berkelmans, Frantz, Badie, Julio C., Tapponnier, Romain, Gally, Josette, 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C., Ferguson, N. D., Bruhn, A. R., Garcia, P. H., Aliaga, F. A., Farias, P. A., Yumha, J. S., Ortiz, C. A., Salas, J. E., Saez, A. A., Vega, L. D., Labarca, E. F., Martinez, F. T., Carreno, N. G., Ye, Z. L., Wu, Y. Q., Huang, X. B., Wang, H. X., Qin, S. H., Zhu, B. H., Liu, J. L., Zhou, F. C., Li, Q. J., Zhang, X. Y., Gao, Y. N., Zhao, X. Y., Li, Y. Y., Li, X. L., Huang, Q. Q., Zhu, W. H., Hang, A. Y., Hua, M. X., Di, Y. D., Ling, L. L., Qin, T. H., Wang, S. H., Vargas, M. P., Jimenez, J. I. S., Rojas, M. A. G., Solis-Quesada, J. E., Ramirez-Alfaro, C. M., Maca, J., Villamagua, B. G., Chiche, J. -D., Arnal, J. -M., Au, S. -M., Beduneau, G., Zogheib, E. H., Santoli, F. L., Besset, S. L., Gelee, B., Danin, P. -E., Crova, P. J., Phan, N. T., Badie, J. C., Herbrecht, J. -E., Declercq, P. -L. M., Rigaud, J. -P., Zein, S. O., Richecoeur, J. R., Combaux, D. M., Lemoal, C., Sauvadet, E. P., Guerin, C., Krassler, J., Schafer, S., Zacharowski, K. D., Reske, A. W., Hopf, H. -B. 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K., Brown, S. M., Bauer, P. R., Gosselin, R. J., Kitch, B. T., Cohen, J. E., Beegle, S. H., Gueret, R. M., Huff, N. G., Lamb, K. D., Oetting, T. W., Mohr, N. M., Kheir, F. M., Schlichting, A. B., Crouch, D. R., Dreyer, K. R., Blakeman, T. C., Baron, R. M., Grijalba, C. Q., Hou, P. C., Hou, S. -K., and Owens, R. L.
- Subjects
Male ,ARDS ,medicine.medical_treatment ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,ARDS reassessment ,ARDS Survival ,Berlin criteria ARDS ,Persisting ARDS ,Critical Care and Intensive Care Medicine ,assisted ventilation ,0302 clinical medicine ,Risk Factors ,030212 general & internal medicine ,risk factor, Adult ,Tidal volume ,comparative study ,education.field_of_study ,Respiratory Distress Syndrome ,Mortality rate ,Remission Induction ,tidal volume ,artificial ventilation ,clinical trial ,immunosuppressive treatment ,adult respiratory distress syndrome ,Middle Aged ,Monte Carlo method ,medicine.anatomical_structure ,classification ,positive end expiratory pressure ,Cardiology ,Disease Progression ,SOFA score ,disease severity ,Female ,Adult ,medicine.medical_specialty ,Population ,disease classification ,Article ,NO ,03 medical and health sciences ,remission ,length of stay ,Anesthesiology ,Internal medicine ,medicine ,pneumonia ,Sequential Organ Failure Assessment Score ,Humans ,human ,education ,Aged ,Mechanical ventilation ,hospital mortality ,Lung ,business.industry ,Risk Factor ,disease association ,Respiratory Distress Syndrome, Adult ,medicine.disease ,major clinical study ,mortality ,Respiration, Artificial ,breathing rate ,030228 respiratory system ,disease exacerbation ,business - Abstract
Purpose: To evaluate patients with resolved versus confirmed ARDS, identify subgroups with substantial mortality risk, and to determine the utility of day 2 ARDS reclassification. Methods: Our primary objective, in this secondary LUNG SAFE analysis, was to compare outcome in patients with resolved versus confirmed ARDS after 24 h. Secondary objectives included identifying factors associated with ARDS persistence and mortality, and the utility of day 2 ARDS reclassification. Results: Of 2377 patients fulfilling the ARDS definition on the first day of ARDS (day 1) and receiving invasive mechanical ventilation, 503 (24%) no longer fulfilled the ARDS definition the next day, 52% of whom initially had moderate or severe ARDS. Higher tidal volume on day 1 of ARDS was associated with confirmed ARDS [OR 1.07 (CI 1.01–1.13), P = 0.035]. Hospital mortality was 38% overall, ranging from 31% in resolved ARDS to 41% in confirmed ARDS, and 57% in confirmed severe ARDS at day 2. In both resolved and confirmed ARDS, age, non-respiratory SOFA score, lower PEEP and P/F ratio, higher peak pressure and respiratory rate were each associated with mortality. In confirmed ARDS, pH and the presence of immunosuppression or neoplasm were also associated with mortality. The increase in area under the receiver operating curve for ARDS reclassification on day 2 was marginal. Conclusions: ARDS, whether resolved or confirmed at day 2, has a high mortality rate. ARDS reclassification at day 2 has limited predictive value for mortality. The substantial mortality risk in severe confirmed ARDS suggests that complex interventions might best be tested in this population. Trial Registration: ClinicalTrials.gov NCT02010073. © 2018, Springer-Verlag GmbH Germany, part of Springer Nature and ESICM.
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- 2018
38. Online learning environments for the promotion of undergraduate research in pandemic times: A case study in an engineering program.
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Montero, L. Cáceres, Velarde, K. Galantini, Arrué, A. Reátegui, and Del Savio, A. A.
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ONLINE education ,CLASSROOM environment ,COVID-19 pandemic ,PANDEMICS ,PHYSIOLOGY education ,UNDERGRADUATES - Abstract
This case study explores the use of online learning environments as an alternative tool for the promotion of undergraduate research culture within an engineering program during the COVID-19 pandemic times. This context entailed the transition from face-to-face to online learning environments, which was taken as an opportunity for the diffusion and socialization of outstanding research projects developed by undergraduate students within the classroom, through the launching of an online event and a virtual permanent exhibition. The results of this case study were measured through quantitative indicators related to the number of research projects submitted by the students for participating in this exhibition, the number of courses participating through these projects, and the number of professors involved. Participation of students and professors increased by 85% and 90%, respectively, comparing the online environment to the previous face-to-face one. Consequently, it was concluded that the use of online learning environments supports the promotion of undergraduate research culture, by increasing the interest of students for the socialization of their research results. [ABSTRACT FROM AUTHOR]
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- 2023
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39. A non-invasive method for an in vivo assessment of corneal epithelium permeability through tetrapolar impedance measurements
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Guimera, A., Gabriel, G., Plata-Cordero, M., Montero, L., Maldonado, M.J., and Villa, R.
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- 2012
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40. AB0145 IgA VASCULITIS AND IgA NEPHROPATHY SHARE A SIMILAR IL33-IL1RL1 ASSOCIATION PATTERN
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Prieto-Peña, D., primary, Remuzgo Martinez, S., additional, Genre, F., additional, Pulito-Cueto, V., additional, Atienza-Mateo, B., additional, Sevilla, B., additional, Llorca, J., additional, Ortego, N., additional, Leonardo, M., additional, Peñalba, A., additional, Martín-Penagos, L., additional, Miranda Fillloy, J. A., additional, Narváez, J., additional, Caminal Montero, L., additional, Collado, P., additional, Fernandez-Nebro, A., additional, Díaz-Cordoves, G., additional, Cigarrán, S., additional, Calviño, J., additional, Cobelo, C., additional, Quiroga Colino, P., additional, Sanchez Perez, J., additional, Rubio-Romero, E., additional, Leon Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Gualillo, O., additional, Martin Ibanez, J., additional, Castañeda, S., additional, Blanco, R., additional, González-Gay, M. A., additional, and López-Mejías, R., additional
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- 2022
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41. AB0146 BAFF, APRIL y BAFFR: DIFFERENTIAL BIOMARKERS BETWEEN IgA VASCULITIS AND IgA NEPHROPATHY?
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Prieto-Peña, D., primary, Genre, F., additional, Remuzgo Martinez, S., additional, Pulito-Cueto, V., additional, Atienza-Mateo, B., additional, Sevilla, B., additional, Llorca, J., additional, Ortego, N., additional, Leonardo, M., additional, Peñalba, A., additional, Martín-Penagos, L., additional, Miranda Fillloy, J. A., additional, Narváez, J., additional, Caminal Montero, L., additional, Collado, P., additional, Fernandez-Nebro, A., additional, Díaz-Cordoves, G., additional, Cigarrán, S., additional, Calviño, J., additional, Cobelo, C., additional, De Argila, D., additional, Vicente-Rabaneda, E. F., additional, Rubio-Romero, E., additional, Leon Luque, M., additional, Blanco-Madrigal, J. M., additional, Galíndez-Agirregoikoa, E., additional, Gualillo, O., additional, Martin Ibanez, J., additional, Castañeda, S., additional, Blanco, R., additional, González-Gay, M. A., additional, and López-Mejías, R., additional
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- 2022
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42. Cost of Traveling to Follow-up Appointments at Kidney Transplant Clinics
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Molina M, Sorolla C, Samsó E, Carcaña M, Martín ML, Jatem E, Pitarch G, Montero L, Lauzurica R, and Segarra A
- Abstract
BACKGROUND: The number of kidney transplant (KT) recipients has increased in recent years, saturating kidney transplant visits at transplant centers (TCs). Furthermore, some patients live far from TCs, which adds displacement costs to their expenses. To solve these problems, joint follow-up of KT recipients has been initiated at TCs and referral hospitals. METHODS: We performed a cross-sectional study in a cohort of 64 KT recipients during joint follow-up in TCs and the Hospital Arnau de Villanova (HAV) using a survey that evaluated the displacement costs as well as the advantages and disadvantages of each. RESULTS: Distance (320 km [IQR, 300-340 km] vs 15 km [IQR, 4-60 km]; P < .001), time (240 minutes [IQR, 210-240 minutes] vs 40 minutes [IQR, 30-68 minutes]; P < .001), total economic cost per visit (€60 [IQR, €50-90] vs €10 [IQR, €2-15]; P < .001), and annual CO(2) emission (32.3 kg vs 1.4 kg; P < .05) were greater when patients traveled to TCs. Nephrologists at both TCs and HAV were rated positively by patients, while the displacement costs associated with travel to the TCs and the smaller size of the HAV were seen as negative aspects. Overall, 93.75% of the KT recipients preferred joint follow-up. CONCLUSIONS: This study suggests that joint follow-up between TCs and referral hospitals is an economic and ecological solution for follow-up in KT recipients living far away and visiting their referral hospital, which is the preferred choice for most patients.
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- 2022
43. Quality of Life in Long-Term Renal Transplant Patients: A Controversial Subject
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Molina M, Sorolla C, Samsó E, Carcaña M, Martín ML, Jatem E, Pitarch G, Montero L, Lauzurica R, and Segarra A
- Abstract
BACKGROUND: Kidney transplant (KT) is the best technique for renal replacement treatment in terms of survival, costs, and quality of life. Several factors have been related to health-related quality of life (HRQOL) at different times after KT. The objectives of the study were to quantify the HRQOL in a prevalent cohort of KT patients and to describe the variables that influenced HRQOL. METHODS: In this cross-sectional study of a cohort of 64 KT patients, we measured HRQOL using the 36-item Short Form Health Survey. Variables measured included the following: physical functioning, role physical (RP), bodily pain (BP), general perception of health, vitality, social functioning (SF), role emotional (RE), and mental health. Demographic and analytical variables were collected. We describe the variables that influenced HRQOL. RESULTS: A large dispersion was observed in the RP, BP, SF, and RE categories. There were no differences in values between men and women who underwent KT. Diabetes, previous dialysis, deceased donor, age, kidney function, anemia, and malnutrition were associated with worse scores. CONCLUSION: This study suggests that HRQOL in KT patients is very heterogeneous and highly polarized. The factors that influence HRQOL are multiple and need to be addressed globally. Further studies are needed to understand the factors that influence HRQOL in the long term.
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- 2022
44. Representaciones sociales de la corrupción y la violencia y su relación con la reflexión socio moral en jóvenes de zonas urbanas y rurales de diversas regiones del Perú
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Carlos Arenas Iparraguirre, María Matalinares C., Victor Montero L., Eli Malvaceda E., Israel Rivera P., and Elsa Sánchez Y.
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reflexión socio-moral ,representaciones sociales ,corrupción ,violencia ,jóvenes ,Psychology ,BF1-990 - Abstract
La investigación identificó las representaciones sociales sobre la corrupción y la violencia y su relación con los niveles de reflexión socio-moral de los jóvenes de procedencia urbana y rural del país. Se evaluó a 268 jóvenes de zonas urbanas y rurales, de ambos sexos, cuyas edades fluctuaban entre 18 y 25 años, se desarrolló grupos focales a fin de identificar las representaciones sociales de la corrupción y la violencia y se aplicó el cuestionario de reflexión socio-moral propuesto Gibbs, Arnold y Morgan y adaptado por Grimaldo (2002). No se halló relación significativa entre la reflexión socio-moral y la representación social de la corrupción y la violencia. Existe un desarrollo moral mayormente ubicado en la concordia interpersonal, aunque un tercio de la población se ubica en una orientación instrumental relativista y el nivel de desarrollo moral alcanzado por los jóvenes corresponde al convencional y preconvencional. Los niveles de reflexión socio-moral en Pucallpa se ubicaría en el Estadio 2 (orientación instrumental relativista) mientras que el resto de regiones evaluadas el Estadio 3 (orientación hacia la concordia interpersonal) sería el predominante. La corrupción sería una práctica social de adaptación que permite la orientación a la concordia interpersonal, en muchos casos se tiene una visión pesimista sobre la posibilidad de eliminarlas. La representación social de la violencia tendría relación directa con los actos de corrupción, en el sentido de dar mayor valor al beneficio individual e inmediato que al bienestar social o colectivo.
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- 2011
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45. Connective Tissue Diseases and Psoriasis
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Cuesta-Montero, L. and Belinchón, I.
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- 2011
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46. Conectivopatías y psoriasis
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Cuesta-Montero, L. and Belinchón, I.
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- 2011
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47. La agenda psicosocial en Perú: autopercepción de logros, representación de eficacia social y responsabilidad social
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Carlos Arenas Iparraguirre and Víctor Montero L.
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agenda psicosocial ,autopercepción ,representación social ,responsabilidad social ,Psychology ,BF1-990 - Abstract
El propósito principal es evidenciar el papel que la psicología social desempeña en respuesta a las demandas sociales, identificar la autopercepción de los logros que los propios psicólogos sociales tienen de su profesión, contrastando ésta con la evidencia que las representaciones sociales de la eficacia que objetivamente se encuentran presentes y enmarcando todo este conjunto de autopercepciones y representaciones sociales en el ámbito de la responsabilidad social. Usando la metodología cualitativa (grupos focales, entrevistas, investigación participativa) se estudian el conjunto de percepciones y representaciones desde la responsabilidad social que le compete a la disciplina psicológica social. El cómo se percibe y representa la eficacia de su quehacer psicológico-social y cuál es la relación con el nivel de representación social que ellos han ido construyendo en el decurso de su formación académico-profesional. Los resultados esperados son demostrar la efectividad de la aplicación de la psicología social en las políticas y programas sociales frente a los problemas sociales prioritarios en el Perú, es decir la agenda y construir indicadores que faciliten el conocimiento de la efectividad de dichos programas en aspectos tales como los formativos, profesionales e investigativos y teóricos desde la propia perspectiva de los actores, los psicólogos sociales, en las diversas regiones del país.
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- 2009
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48. Directional analysis of jamming attack for connected vehicular platoons
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Valiente, R., primary, Montero, L., additional, Ballesteros, C., additional, and Jofre, L., additional
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- 2022
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49. POSB9 Short- and Long-Term Performance of Mechanical Versus Biological Prostheses for Aortic Valve Replacement in Patients with Severe Symptomatic Aortic Stenosis over 65 Years
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Pérez, D, primary, Maroto, L, additional, Cobiella, J, additional, Montero, L, additional, Torres, B, additional, Carnero, M, additional, Marti Sanchez, B, additional, Diaz, A, additional, and Cuervo, J, additional
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- 2022
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50. Photocatalytic properties of Cu-containing ZnO nanoparticles and their antifungal activity against agriculture-pathogenic fungus
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Paraguay-Delgado, F., primary, Hermida-Montero, L. A., additional, Morales-Mendoza, J. E., additional, Durán-Barradas, Z., additional, Mtz-Enriquez, Arturo I., additional, and Pariona, Nicolaza, additional
- Published
- 2022
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- View/download PDF
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