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128 results on '"Monson, J.R.T."'

9. Piezoelectric lithotripsy and soft tissue injury. Safety limits in the experimental and clinical setting

Author

Darzi, A., Reid, I., Kay, Elaine, Monson, J.R.T., Tanner, W.A., and Keane, F.B.V.

Subjects
Gallbladder -- Physiological aspects, Gallstones -- Care and treatment, Shock waves -- Physiological aspects, Ultrasonic lithotripsy -- Physiological aspects, Health
Abstract

Gallstones, concretions of solidified cholesterol that may block the passageway from the gall bladder, are a painful affliction that formerly were only treatable by surgery. In recent years, lithotripsy, a technique that involves the shattering of these stones by shock waves generated outside the body by a machine, has come to be recognized as an alternative treatment. It is claimed that the shock waves produced by these devices (lithotripters) selectively destroy the noncompliant gallstones, while having little effect on the soft tissues surrounding them. To investigate this safety claim, two studies, one using an animal model (anesthetized guinea pigs) and another using human subjects, were performed. The guinea pigs were subjected to one of several doses of shock waves (6000 to 48000 shocks) applied at one of several different frequencies (2.5 to 20 shock waves per second). The amount of tissue damage that occurred was proportional to the number of shock waves administered. Repeated low doses did not produce cumulative damage. Even at the high doses, satisfactory healing of soft tissue damage occurred within one month after treatment. Human subjects were administered either 6000 or 36000 shock waves one day before elective surgery for gall bladder removal. Patients receiving the higher number of shock waves suffered more tissue damage than those receiving the low dose. As in the animal studies, repeated low doses (up to six treatments at weekly intervals) produced no cumulative damaging effect. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1990

29. Evaluation of quality of life after laparoscopic surgery: Evidence-based guidelines of the European Association for Endoscopic Surgery (E.A.E.S).

Author

Korolija, D, Sauerland, S, Wood-Dauphinée, S, Abbou, C.C., Eypasch, E, García Caballero, M, Lumsden, M.A., Millat, B, Monson, J.R.T., Nilsson, Gunilla, Pointner, R, Schwenk, W, Shamiyeh, A, Szold, A, Targarona, E, Ure, B, Neugebauer, E, Korolija, D, Sauerland, S, Wood-Dauphinée, S, Abbou, C.C., Eypasch, E, García Caballero, M, Lumsden, M.A., Millat, B, Monson, J.R.T., Nilsson, Gunilla, Pointner, R, Schwenk, W, Shamiyeh, A, Szold, A, Targarona, E, Ure, B, and Neugebauer, E

Published
2004

38. Colorectal 04

Author

Baker, R.P., primary, Titu, L.V., additional, Hartley, J.E., additional, Lee, P.W.R., additional, Duthie, G.S., additional, and Monson, J.R.T., additional

Published
2002
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