Search

Your search keyword '"Monnier, A.-S."' showing total 20 results
Start Over Author "Monnier, A.-S."
20 results on '"Monnier, A.-S."'

7. XXVth European Colloquium on Heterocyclic Chemistry (ECHC25), PO-31

Author

Haddad F. Rouatbi C. Mhiri S. Boudriga M. Askri K. Ciamala A. Khatyr M. Knorr K. Monnier-Jobé, S., Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213) (UTINAM), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)

Published
2012

17. Comparison of AMPLICOR® and Hybrid Capture II® assays for high risk HPV detection in normal and abnormal liquid-based cytology: Use of INNO-LiPA Genotyping assay to screen the discordant results

Author

Mo, L.Z., Monnier-Benoit, S., Kantelip, B., Petitjean, A., Riethmuller, D., Prétet, J.L., and Mougin, C.

Subjects
*PAPILLOMAVIRUSES, *CYTOLOGY, *CELLS, *ONCOGENIC DNA viruses, *DISEASES in women
Abstract

Abstract: The study was aimed to evaluate the feasibility of detecting human papillomavirus (HPV) in women with normal or abnormal cervical smears using the Roche Amplicor MWP HPV Test. We compared by AMPLICOR® Test and Hybrid Capture II® (HCII®) Test, the prevalence of HR-HPV in 470 cervical samples including 55 samples with WNL cytology, 208 ASC-US, 193 LGSIL and 14 HGSIL. Samples with discordant results were retested with INNO-LiPA Genotyping HPV Test v2. The HR-HPV positivity in WNL cytology samples was similar (21.8%) by AMPLICOR® and HCII®. In ASC-US, the HPV positivity was 42.3% by both tests. In LGSIL, HPV positivity was 66.3% and 66.8% by AMPLICOR® and HCII®, respectively. In HGSIL, 92.8% of samples were positive by AMPLICOR® and 85.7% by HCII®. The agreement of both tests was 96.2% with a Kappa value of 0.92. Eighteen cases were discordant: 9 HCII® positive/AMPLICOR® negative and 9 HCII® negative/AMPLICOR® positive. The INNO-LiPA test revealed HPV positivity in every case. Interestingly, all HCII®+/AMPLICOR®− samples were found to harbour HPV53. As for the HCII®−/AMPLICOR®+ samples, 8 demonstrated a multiple infection with HR 16- and/or 18- and/or 56-phylogenetically related HPV types. Moreover, two of these samples were co-infected with HPV6 and two other with HPV54. By using consensus HR-HPV as our reference HPV positivity, the sensitivity (96.6%) and specificity (100%) of AMPLICOR® was similar to that of HCII® Test. The AMPLICOR® HPV Test is sensitive, specific, feasible and appropriate for routine HPV detection. [Copyright &y& Elsevier]

Published
2008
Full Text
View/download PDF

19. A monocular leader-follower system for small mobile robots

Author

Monnier, Camille S., German, Stan, and Ostapchenko, Andrey

Abstract

Current generation UGV control systems typically require operators to physically control a platform through teleoperation, even for simple tasks such as travelling from one location to another. While vision-based control technologies promise to significantly reduce the burden on UGV operators, most schemes rely on specialized sensing hardware, such as LIDAR or stereo cameras, or require additional operator-worn equipment or markers to differentiate the leader from nearby pedestrians. We present a system for robust leader-follower control of small UGVs using only a single monocular camera, which is ubiquitous on mobile platforms. The system allows a user to control a mobile robot by leading the way and issuing commands through arm/hand gestures, and differentiates between the leader and nearby pedestrians. The software achieves this by integrating efficient algorithms for pedestrian detection, online appearance learning, and kinematic tracking with a lightweight technique for camera-based gesture recognition.

Published
2012
Full Text
View/download PDF

20. A novel gene expression signature in peripheral blood mononuclear cells for early detection of colorectal cancer

Author

Nichita, C., Ciarloni, L., Monnier-Benoit, S., Hosseinian, S., Dorta, G., Rüegg, Curzio, Nichita, C., Ciarloni, L., Monnier-Benoit, S., Hosseinian, S., Dorta, G., and Rüegg, Curzio

Abstract

Background: Early detection and treatment of colorectal adenomatous polyps (AP) and colorectal cancer (CRC) is associated with decreased mortality for CRC. However, accurate, non-invasive and compliant tests to screen for AP and early stages of CRC are not yet available. A blood-based screening test is highly attractive due to limited invasiveness and high acceptance rate among patients.Aim: To demonstrate whether gene expression signatures in the peripheral blood mononuclear cells (PBMC) were able to detect the presence of AP and early stages CRC.Methods: A total of 85 PBMC samples derived from colonoscopy-verified subjects without lesion (controls) (n = 41), with AP (n = 21) or with CRC (n = 23) were used as training sets. A 42-gene panel for CRC and AP discrimination, including genes identified by Digital Gene Expression-tag profiling of PBMC, and genes previously characterised and reported in the literature, was validated on the training set by qPCR. Logistic regression analysis followed by bootstrap validation determined CRC- and AP-specific classifiers, which discriminate patients with CRC and AP from controls.Results: The CRC and AP classifiers were able to detect CRC with a sensitivity of 78% and AP with a sensitivity of 46% respectively. Both classifiers had a specificity of 92% with very low false-positive detection when applied on subjects with inflammatory bowel disease (n = 23) or tumours other than CRC (n = 14).Conclusion: This pilot study demonstrates the potential of developing a minimally invasive, accurate test to screen patients at average risk for colorectal cancer, based on gene expression analysis of peripheral blood mononuclear cells obtained from a simple blood sample.

Catalog

Books, media, physical & digital resources
See catalog results