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193 results on '"Mondal, Debapriya"'

1. Arsenic and other geogenic contaminants in global groundwater

Author

Mukherjee, Abhijit, Coomar, Poulomee, Sarkar, Soumyajit, Johannesson, Karen H., Fryar, Alan E., Schreiber, Madeline E., Ahmed, Kazi Matin, Alam, Mohammad Ayaz, Bhattacharya, Prosun, Bundschuh, Jochen, Burgess, William, Chakraborty, Madhumita, Coyte, Rachel, Farooqi, Abida, Guo, Huaming, Ijumulana, Julian, Jeelani, Gh, Mondal, Debapriya, Nordstrom, D. Kirk, Podgorski, Joel, Polya, David A., Scanlon, Bridget R., Shamsudduha, Mohammad, Tapia, Joseline, and Vengosh, Avner

Published
2024
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7. Perfluoroalkyl Substances, Sex Hormones, and Insulin-like Growth Factor-1 at 6–9 Years of Age: A Cross-Sectional Analysis within the C8 Health Project

Author

Lopez-Espinosa, Maria-Jose, Mondal, Debapriya, Armstrong, Ben G, Eskenazi, Brenda, and Fletcher, Tony

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Pediatric, Alkanesulfonic Acids, Caprylates, Child, Cross-Sectional Studies, Environmental Exposure, Environmental Pollutants, Female, Fluorocarbons, Gonadal Steroid Hormones, Humans, Insulin-Like Growth Factor I, Male, Environmental Sciences, Medical and Health Sciences, Toxicology, Biomedical and clinical sciences, Environmental sciences, Health sciences
Abstract

BackgroundExposure to some perfluoroalkyl substances (PFAS), such as perfluorohexane sulfonate (PFHxS), perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA), may alter levels of sex hormones and insulin-like growth factor-1 (IGF-1) in animals. Human studies on this topic are scarce, and none have been conducted in young children.ObjectivesWe investigated the relationship between levels of PFAS and estradiol, total testosterone, and IGF-1 in 2,292 children (6-9 years of age) from the C8 Health Project who lived near a chemical plant in the Mid-Ohio Valley (USA) with local contamination from PFOA.MethodsSerum samples were collected in 2005-2006 and analyzed for PFAS, sex hormones, and IGF-1. Results from regression models were expressed as the adjusted percentage difference (95% CI) per sex-specific interquartile range (IQR) increment of each PFAS serum concentration. Analyses by PFAS quartiles were also conducted.ResultsMedian concentrations of PFHxS, PFOA, PFOS, and PFNA were 8, 35, 22, and 1.7 ng/mL in boys and 7, 30, 21, and 1.7 ng/mL in girls. In boys, PFOA concentrations were significantly associated with testosterone levels (-4.9%; 95% CI: -8.7, -0.8%); PFOS with estradiol (-4.0%; 95% CI: -7.7, -0.1%), testosterone (-5.8%; 95% CI: -9.4, -2.0%), and IGF-1 (-5.9%; 95% CI: -8.3, -3.3%); and PFNA with IGF-1 (-3.5%; 95% CI: -6.0, -1.0%). In girls, significant associations were found between PFOS and testosterone (-6.6%; 95% CI: -10.1, -2.8%) and IGF-1 (-5.6%; -8.2, -2.9%); and PFNA and IGF-1 (-3.8%; 95% CI: -6.4, -1.2%). In both sexes, the magnitudes of the associations decreased monotonically across quartiles for both testosterone and IGF-1 in relation to PFOS, and for IGF-1 and PFNA in girls.ConclusionsTo our knowledge, this is the first study suggesting that PFAS are associated with lower levels of IGF-1 and sex hormones in young children.CitationLopez-Espinosa MJ, Mondal D, Armstrong BG, Eskenazi B, Fletcher T. 2016. Perfluoroalkyl substances, sex hormones, and insulin-like growth factor-1 at 6-9 years of age: a cross-sectional analysis within the C8 Health Project. Environ Health Perspect 124:1269-1275; http://dx.doi.org/10.1289/ehp.1509869.

Published
2016

10. Breastfeeding: A Potential Excretion Route for Mothers and Implications for Infant Exposure to Perfluoroalkyl Acids

Author

Mondal, Debapriya, Weldon, Rosana H, Armstrong, Ben G, Gibson, Lorna J, Lopez-Espinosa, Maria-Jose, Shin, Hyeong-Moo, and Fletcher, Tony

Subjects
perfluorinated compounds, human-milk, united-states, serum, perfluorooctanoate, lactation, chemicals, plasma, ethers, women
Abstract

Background: The presence of perfluoroalkyl acids (PFAAs) in breast milk has been documented, but their lactational transfer has been rarely studied. Determination of the elimination rates of, these chemicals during breastfeeding is important and critical for assessing exposure in mothers, and infants., O b jectives: We aimed to investigate the association between breastfeeding and maternal serum, concentrations of perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorononanoic, acid (PFNA), and perfluorohexane sulfonate (PFHxS). For a subset of the population, for, whom we also have their infants' measurements, we investigated associations of breastfeeding with, infant serum PFAA concentrations., Methods: The present analysis included 633 women from the C8 Science Panel Study who had, a child < 3.5 years of age and who provided blood samples and reported detailed information on, breastfeeding at the time of survey. PFAA serum concentrations were available for all mothers and, 8% (n=49) of the infants. Maternal and infant serum concentrations were regressed on duration of, breastfeeding. R esults: Each month of breastfeeding was associated with lower maternal serum concentrations, of PFOA (-3%, 95% CI:-5, -2%), PFOS (-3%, 95% CI:-3, -2%), PFNA (-2%, 95% CI, -2, -1%), and PFHxS (-1%, 95% CI:-2, 0%). The infant PFOA and PFOS serum concentrations, were 6% (95% CI: 1, 10%) and 4% (95% CI: 1, 7%) higher per month of breastfeeding., C onclusions: Breast milk is the optimal food for infants, but is also a PFAA excretion route for, lactating mothers and exposure route for nursing infants.

Published
2013

16. Chronic Exposure to Drinking Water Arsenic and Gallbladder Cancer Risk: Preliminary Evidence from Endemic Regions of India

Author

Shridhar, Krithiga, primary, Krishnatreya, Manigreeva, additional, Sarkar, Soumyajit, additional, Kumar, Ranjit, additional, Kondal, Dimple, additional, Kuriakose, Steena, additional, RS, Vinutha, additional, Singh, Amulya K., additional, Kataki, Amal Chandra, additional, Ghosh, Ashok, additional, Mukherjee, Abhijit, additional, Prabhakaran, D., additional, Mondal, Debapriya, additional, Prabhakaran, Poornima, additional, and Dhillon, Preet K., additional

Published
2023
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22. Lifetime Chronic Arsenic Exposure and Gallbladder Cancer Risk: Evidence from Endemic Regions of India

Author

Shridhar, Krithiga, primary, Mondal, Debapriya, additional, Krishnatreya, Manigreeva, additional, Kumar, Ranjit, additional, Kondal, Dimple, additional, Kuriakose, Steena, additional, Ragavaiah Sarma, Vinutha, additional, Sarkar, Soumyajit, additional, Sarma Barthakur, Sumita, additional, Bharali, Gayatri, additional, Kumar Singh, Amulya, additional, Chandra Kataki, Amal, additional, Ghosh, Ashok, additional, Mukherjee, Abhijit, additional, Prabhakaran, Dorairaj, additional, Prabhakaran, Poornima, additional, and Kaur Dhillon, Preet, additional

Published
2022
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41. Arsenic exposure from food exceeds that from drinking water in endemic area of Bihar, India

Author

Mondal, Debapriya, primary, Rahman, Mohammad Mahmudur, additional, Suman, Sidharth, additional, Sharma, Pushpa, additional, Siddique, Abu Bakkar, additional, Rahman, Md. Aminur, additional, Bari, A.S.M. Fazle, additional, Kumar, Ranjit, additional, Bose, Nupur, additional, Singh, Shatrunjay Kumar, additional, Ghosh, Ashok, additional, and Polya, David A., additional

Published
2021
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50. Wheat is an emerging exposure route for arsenic in Bihar, India

Author

Suman, Sidharth, primary, Sharma, Pushpa Kumari, additional, Siddique, Abu Bakkar, additional, Rahman, Md. Aminur, additional, Kumar, Ranjit, additional, Rahman, Mohammad Mahmudur, additional, Bose, Nupur, additional, Singh, Shatrunjay Kumar, additional, Ghosh, Ashok Kumar, additional, Matthews, Helen, additional, and Mondal, Debapriya, additional

Published
2020
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