409 results on '"Molinu, A"'
Search Results
2. Mediterranean Wild Pear Fruits as a Neglected but Valuable Source of Phenolic Compounds
- Author
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Maria Giovanna Molinu, Federico Sanna, Guy D’hallewin, Giovanni Antonio Re, Leonardo Sulas, and Giovanna Piluzza
- Subjects
Pyrus spinosa ,P. pyraster ,peel ,core ,flesh ,bioactive compounds ,Science - Abstract
The genus Pyrus has a long history in Sardinia (Italy), where two wild pear species (P. spinosa Forssk. and P. pyraster (L.) Burgsd.) and Pyrus communis L. cultivars are extensively distributed. Even if neglected, these taxa represent well-adapted key resources for redesigning sustainable farming systems. This report aims at shedding light on the phenolic fingerprint and antioxidant properties of wild pear fruits and comparing their traits with those of the studied pear cultivar germplasm (PCG). Fruits of wild pear species were collected, and flesh, peel, and core subsamples were analyzed. Moreover, available data from previous research on PCG were analyzed. The contents of total phenolics (TotP), total flavonoids (TotF), and condensed tannins (CT), as well as the antioxidant capacity, were similar in the flesh of the two wild species. However, P. spinosa had significantly higher values of TotP (89 g GAE kg−1 DM) and CT (33 g DE kg−1 DM) in the peel. Eleven individual phenolic compounds were identified and quantified in the fruit flesh, 14 in both peel and core. For both wild species, arbutin and chlorogenic acid were the main phenolic compounds, followed by the quercetin glycosides. Comparing the antioxidant capacity and TotF fruit flesh values of wild pears with those of PCG, the latter resulted up to 15-fold lower. The wild types showed unique metabolite profiles. Results support novel insights on the phytochemicals of wild pear fruits.
- Published
- 2024
- Full Text
- View/download PDF
3. Antimicrobial and antibiofilm activities of pomegranate peel phenolic compounds: Varietal screening through a multivariate approach
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Amira Salim, Pierfrancesco Deiana, Francesco Fancello, Maria Giovanna Molinu, Mario Santona, and Severino Zara
- Subjects
Punica granatum ,Agrobiodiversity ,OPLS-DA ,Punicalagin ,Staphyloccocus aureus ,Listeria monocytogenes ,Biochemistry ,QD415-436 - Abstract
Pomegranates are rich in phenolic compounds and known for their antioxidant, anti-inflammatory, and anticancer properties. The highest concentration of these compounds is found in the peel (exocarp and mesocarp), which constitutes about 50% of the whole fresh fruit. These bioactive phytochemicals exhibit a broad spectrum of antimicrobial effects against both Gram-negative and Gram-positive bacteria, as well as fungi. In the present paper, the chemical composition and antimicrobial activity of the peel (exocarp and mesocarp) from seven Punica granatum varieties (Wonderful, Mollar de Elche, Primosole, Sassari 1, Sassari 2, Sassari 3, and Arbara Druci) grown in Sardinia (Italy) were evaluated. Polar phenols, flavonoids, condensed tannins, and anthocyanin contents were evaluated by extraction with water at 20 and 40 °C. Orthogonal projections to latent structures discriminant analysis (OPLS-DA) was used to characterize each variety according to the chemical composition of the pomegranate peel extracts (PPEs). The antimicrobial and antibiofilm activities of each PPE were further tested in vitro against Staphyloccocus aureus, Listeria monocytogenes, Salmonella bongori, Escherichia coli, Lacticaseibacillus casei and Limosilactobacillus reuteri. Gram-positive species were more sensitive than Gram-negative to the extracts tested. Antimicrobial activity was shown against S. aureus and L. monocytogenes strains, whereas less, even no activity was found against S. bongori and E. coli strains. The PPEs from Mollar de Elche, Primosole, and Sassari 3 showed the highest antimicrobial activities at concentrations that varied from 0.19 to 1.50 mg/mL, with biofilm activity being reduced by more than 70%. These activities were positively related to the punicalagin, flavonoid, and chlorogenic acid content of the extracts. Finally, regarding the pro-technological bacterial strains, La. casei and Li. reuteri showed very low, even no sensitivity to the used of the specific PPEs with high concentrations. This study proposes a formulation of pomegranate peel extract that valorizes agro-industrial waste in the context of sustainability and circular economy. Pomegranate extracts should be considered potential sources of natural, plant-derived antimicrobials, providing an alternative to artificial antimicrobial products.
- Published
- 2023
- Full Text
- View/download PDF
4. Athematic infinitives in Old Sardinian
- Author
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Molinu, Lucia, primary
- Published
- 2023
- Full Text
- View/download PDF
5. Antioxidant and Anticancer Activity of Pericarp Water Extracts of Mediterranean Ancient Chestnut Accessions
- Author
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Ylenia Spissu, Maria Giovanna Molinu, Guy D’hallewin, Giulia Sanna, Gavina Rita Serra, Antonella Muroni, and Antonio Barberis
- Subjects
chestnut biodiversity ,pericarp ,water extraction ,antioxidant activity ,cancer cells ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The residue of chestnut processing generates a large amount of waste material, a resource not adequately exploited. The antioxidant and antitumoral properties of cold and hot water extracts from discarded pericarp of four chestnut Sardinian accessions and one marron variety were studied. The antioxidant capacity of the extracts was determined by spectrophotometric and electrochemical tests. The 1,1-diphenyl-2-pic-rylhydrazyl (DPPH) and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) results were highly correlated with each other; likewise, a good correlation was found between Ferric Reducing Antioxidant Power (FRAP) and cyclic voltammetry (CV) values, both based on the direct transfer of electrons. The antiproliferative effect on normal cells (fibroblasts), and on colon (RKO and SW48) and breast (MCF7) cancer cells was evaluated. Additionally, this paper marks the first application of chestnut extracts to investigate their effects on melanoma (B16F10) cells. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test demonstrated that temperature and different extraction times significantly influenced the growth of cells, both normal and tumor. The fibroblast growth was significantly inhibited by moderate doses of cold extracts, while the GI50 values calculated for hot extracts were high, regardless of the accession or cultivar. An even more marked inhibitory action of the cold extracts was observed both on the growth of RKO and SW48 cells and on B16F10 melanoma cells. Otherwise, an extract concentration, both cold and hot, of no less than 243 µg mL−1 is required to achieve a 50% inhibition of MCF7 cell growth.
- Published
- 2024
- Full Text
- View/download PDF
6. Antimicrobial and antibiofilm activities of pomegranate peel phenolic compounds: Varietal screening through a multivariate approach
- Author
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Salim, Amira, Deiana, Pierfrancesco, Fancello, Francesco, Molinu, Maria Giovanna, Santona, Mario, and Zara, Severino
- Published
- 2023
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7. Phonological and Morphological Conditioning
- Author
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Floricic, Franck, primary and Molinu, Lucia, additional
- Published
- 2022
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- View/download PDF
8. Antioxidants in Fruit Fractions of Mediterranean Ancient Pear Cultivars
- Author
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Giovanna Piluzza, Giuseppe Campesi, Guy D’hallewin, Maria Giovanna Molinu, Giovanni Antonio Re, Federico Sanna, and Leonardo Sulas
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rainfed environment ,biodiversity ,scattered fruit trees ,extensive farming ,peel ,peduncle ,Organic chemistry ,QD241-441 - Abstract
Background: The genetic diversity of Sardinian pear germplasm has received limited attention regarding its chemical composition. Understanding this composition can aid in the setting up of resilient, extensive groves that offer multiple products and ecosystem services. This research aimed at investigating the antioxidant properties and phenolic compounds of ancient pear cultivars grown extensively in Sardinia (Italy); Methods: the cultivars Buttiru, Camusina, Spadona, and Coscia (as a reference) were compared. Fruit samples were manually peeled and cut. Their flesh, peel, core, and peduncle were frozen separately, lyophilized, and milled before being analysed; Results: The content of total phenolics (TotP), total flavonoids (TotF), condensed tannins (CT), and antioxidant capacity in each fruit part varied significantly among the cultivars. The TotP content was high in the peduncle (42.2–58.8 g GAE kg−1 DM) and low in flesh (6.4–17.7 g GAE kg−1 DM); Conclusions: the highest values of antioxidant capacity, TotP, NTP, TotF, and CT were found in the flesh of the cultivar Buttiru and in the peel of the cultivar Camusina. Chlorogenic acid was the major individual phenolic compound in peel, flesh and core, whereas arbutin was mostly present in the peduncle. Results can contribute to revise target exploitations of underutilized ancient pear cultivars.
- Published
- 2023
- Full Text
- View/download PDF
9. Mediterranean Wild Pear Fruits as a Neglected but Valuable Source of Phenolic Compounds.
- Author
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Molinu, Maria Giovanna, Sanna, Federico, D'hallewin, Guy, Re, Giovanni Antonio, Sulas, Leonardo, and Piluzza, Giovanna
- Subjects
COMMON pear ,PHENOLS ,SUSTAINABLE agriculture ,FRUIT ,PEARS ,FRUIT extracts - Abstract
The genus Pyrus has a long history in Sardinia (Italy), where two wild pear species (P. spinosa Forssk. and P. pyraster (L.) Burgsd.) and Pyrus communis L. cultivars are extensively distributed. Even if neglected, these taxa represent well-adapted key resources for redesigning sustainable farming systems. This report aims at shedding light on the phenolic fingerprint and antioxidant properties of wild pear fruits and comparing their traits with those of the studied pear cultivar germplasm (PCG). Fruits of wild pear species were collected, and flesh, peel, and core subsamples were analyzed. Moreover, available data from previous research on PCG were analyzed. The contents of total phenolics (TotP), total flavonoids (TotF), and condensed tannins (CT), as well as the antioxidant capacity, were similar in the flesh of the two wild species. However, P. spinosa had significantly higher values of TotP (89 g GAE kg
−1 DM) and CT (33 g DE kg−1 DM) in the peel. Eleven individual phenolic compounds were identified and quantified in the fruit flesh, 14 in both peel and core. For both wild species, arbutin and chlorogenic acid were the main phenolic compounds, followed by the quercetin glycosides. Comparing the antioxidant capacity and TotF fruit flesh values of wild pears with those of PCG, the latter resulted up to 15-fold lower. The wild types showed unique metabolite profiles. Results support novel insights on the phytochemicals of wild pear fruits. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
10. Seasonal variation for leaf bromatological traits and its relationship with phenolic composition in a Mediterranean population of Plantago lanceolata L. under exploitation for multiple uses
- Author
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Piluzza, Giovanna, primary, Sanna, Federico, additional, Campesi, Giuseppe, additional, Molinu, Maria Giovanna, additional, Re, Giovanni Antonio, additional, and Sulas, Leonardo, additional
- Published
- 2023
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- View/download PDF
11. Subterranean Clover and Sulla as Valuable and Complementary Sources of Bioactive Compounds for Rainfed Mediterranean Farming Systems
- Author
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Maria Giovanna Molinu, Leonardo Sulas, Giuseppe Campesi, Giovanni Antonio Re, Federico Sanna, and Giovanna Piluzza
- Subjects
Sulla coronaria ,Trifolium subterraneum ,fodder ,growth stage ,phenolic compounds ,Botany ,QK1-989 - Abstract
Mediterranean pasture and forage legumes are important components of sustainable production systems. Subterranean clover and sulla represent key species having proven high agronomic value and traits for production and multiple services. Our research investigated the potential of the abovementioned species as a source of phenolic compounds and antioxidants for contributing to support their full exploitation in the fodder, animal welfare, and nutraceutical sectors. Antioxidant capacity, as well as the content of total phenolic compounds and individual phenolic compounds, was determined in subterranean clover and sulla shoots at the vegetative, flower bud, flowering, and seed ripening phenological stages. The antioxidant capacity and the phenolic content were affected significantly by harvest time. In subterranean clover, 10 individual phenolic compounds were detected, and isoflavones were the most abundant (3.19–18.27 mg·g−1 DM). Eleven phenolic compounds were identified in sulla shoots, and chlorogenic acid (0.76–3.43 mg·g−1 DM) and diosmin (3.64–4.94 mg·g−1 DM) were the most represented compounds at the vegetative and flower bud stage. On the basis of our findings, a complementary utilization of both legume species is suggested; this might ensure the exploitation of all phenolic compounds in view of the potential benefits for animal production and health.
- Published
- 2023
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12. The chemical composition of Italian virgin olive oils
- Author
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Deiana, Pierfrancesco, primary, Filigheddu, Maria Rosaria, additional, Dettori, Sandro, additional, Culeddu, Nicola, additional, Dore, Antonio, additional, Molinu, Maria Giovanna, additional, and Santona, Mario, additional
- Published
- 2021
- Full Text
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13. List of contributors
- Author
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Abia, Rocio, primary, Abouloifa, H., additional, Adriana, Morales-Martínez, additional, Aggarwal, Diwakar, additional, Aggarwal, Vaishali, additional, Alicia, Sánchez-Mendoza, additional, Andreadou, Ioanna, additional, Angeles-Lo´pez, Quetzalli D., additional, Argüelles, Sandro, additional, Asehraou, A., additional, Audi, Namaa, additional, Ayala, Antonio, additional, Ayoub, Nehad M., additional, Badiu, Diana, additional, Badria, Farid A., additional, Barbouti, Alexandra, additional, Batanero, Eva, additional, Batarseh, Yazan S., additional, Baumann, Leslie S., additional, Ben Salah, R., additional, Bermudez, Beatriz, additional, Blanco, Santos, additional, Borras-Linares, Isabel, additional, Brasca, M., additional, Brenes, Manuel, additional, Perez-Calabuig, Ana M., additional, Cancilla, John C., additional, Cano, Mercedes, additional, Carbone, Fabrizio, additional, Carrera-González, María Pilar, additional, Casas, Rosa, additional, Ceccanti, Mauro, additional, Chaldakov, George N., additional, Covas, María-Isabel, additional, Culeddu, Nicola, additional, Cumaoğlu, Ahmet, additional, Curiel, José Antonio, additional, Damiano, Fabrizio, additional, de Castro, Antonio, additional, de Felipe, Félix López, additional, de la Torre, Rafael, additional, de las Rivas, Blanca, additional, Deiana, Pierfrancesco, additional, Dekanski, Dragana, additional, Dettori, Sandro, additional, Di Stefano, Vita, additional, Domínguez-Vías, German, additional, Dore, Antonio, additional, D’hallewin, G., additional, El Sayed, Khalid A., additional, Elgazar, Abdullah A., additional, Emanuelli, Tatiana, additional, Ferraguti, Giampiero, additional, Filigheddu, Maria Rosaria, additional, Fiore, Marco, additional, Fitó, Montserrat, additional, Francisca, Pérez-Severiano, additional, Fujiwara, Yoko, additional, Galaris, Dimitrios, additional, García, Pedro, additional, Ghabbour, N., additional, Giudetti, Anna Maria, additional, Gnoni, Antonio, additional, Gnoni, Gabriele Vincenzo, additional, Goulas, Vlasios, additional, Greco, Antonio, additional, Guclu, Gamze, additional, Haghbeen, Kamahldin, additional, Handjani, Farhad, additional, Heydari, Mojtaba, additional, Hosseini Mazinani, Mehdi, additional, Ishikawa, Tomoko, additional, Iuliano, Luigi, additional, Joel, Jiménez-Gómez, additional, Joshi, Asavari, additional, Juan, M. Emília, additional, Jugreet, Bibi Sharmeen, additional, Kaddoumi, Amal, additional, Kailis, Stanley George, additional, Kanavaros, Panagiotis, additional, Karboune, S., additional, Kelebek, Hasim, additional, Kitsoulis, Panagiotis, additional, Kouka, Paraskevi, additional, Kouretas, Demetrios, additional, Ktari, N., additional, Kumar, Gaurav, additional, Kumar, Manoj, additional, Landete, José María, additional, Lauretti, Elisabetta, additional, Lemus-Conejo, Ana, additional, Lombardo, Luca, additional, Longo, Serena, additional, Pradana-Lopez, Sandra, additional, Lopez, Sergio, additional, Lopez-Millan, Belen, additional, López-López, Antonio, additional, Lozano-Sánchez, Jesús, additional, Madar, Zecharia, additional, Mahomoodally, Mohamad Fawzi, additional, Mañas, Mariano, additional, Martinez-Victoria, Emilio, additional, Martinez-Burgos, Maria Alba, additional, Martínez-Martos, José Manuel, additional, Masre, Siti Fathiah, additional, Medina, Eduardo, additional, Medina, Rafael, additional, Menendez, Javier A., additional, Millan-Linares, Maria C., additional, Mittal, Sonam, additional, Mohammadnejad, Parvin, additional, Molinu, Maria Giovanna, additional, Montaño, Alfredo, additional, Montserrat-de la Paz, Sergio, additional, Muñoz, Mario, additional, Muñoz, Rosario, additional, Muriana, Francisco J.G., additional, Nenadis, N., additional, Nychas, G.-J.E., additional, Ortega-García, Francisca, additional, Ortega-Gomez, Almudena, additional, Pacheco, Yolanda M., additional, Panagou, E.Z., additional, Papoti, V.T., additional, Pariente, Jose Antonio, additional, Parvizi, Mohammad Mahdi, additional, Pathak, Kaveri, additional, Peinado, M. Ángeles, additional, Peragón, Juan, additional, Petrella, Carla, additional, Čabarkapa-Pirkovic, Andrea, additional, Planas, Joana M., additional, Plastina, Pierluigi, additional, Praticò, Domenico, additional, Prieto, Isabel, additional, Rajendram, Rajkumar, additional, Ralli, Massimo, additional, Ramírez-Expósito, María Jesús, additional, Ramírez-Sánchez, Manuel, additional, Rasouli, Hassan, additional, Al Rihani, Sweilem B., additional, Rodríguez, Héctor, additional, Rodríguez-López, Paloma, additional, Rokni, Y., additional, Romero, Concepción, additional, Rosillo, Maria A., additional, Ruiz-Barba, José Luis, additional, Saalaoui, E., additional, Sacanella, Emilio, additional, Sadeer, Nabeelah Bibi, additional, Sak, Katrin, additional, Saki, Maryam, additional, Salimonti, Amelia, additional, Sánchez, Antonio-Higinio, additional, Santona, Mario, additional, Segarra, Ana Belén, additional, Segura-Carretero, Antonio, additional, Selli, Serkan, additional, Sergio, Montes, additional, Sethi, Gautam, additional, Seyedebrahimi, Seyede Sanaz, additional, Shahbaz, Mana, additional, Sharma, Dhvani, additional, Soares, Mario J, additional, Spremo-Potparević, Biljana, additional, Stark, Aliza Hannah, additional, Suroowan, Shanoo, additional, Suvarna, Vasanti, additional, Tahiri, Iasim, additional, Tarani, Luigi, additional, Tassou, C.C., additional, Topalović, Dijana, additional, Torrecilla, José S., additional, Tseti, Ioulia, additional, Tsimidou, M.Z., additional, Tsoumani, Maria, additional, Tuli, Hardeep Singh, additional, Varela, Lourdes M., additional, Veskoukis, Aristidis S., additional, Villalba, Mayte, additional, Weisberg, Edmund M., additional, Yago, Maria Dolores, additional, Yang, Euitaek, additional, Yerer, Mükerrem Betül, additional, Zanwar, Anand, additional, Zelasco, Samanta, additional, and Živković, Lada, additional
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- 2021
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14. Oxidative stability of plant hydroalcoholic extracts assessed by EPR spin trapping under forced ageing conditions: A myrtle case study
- Author
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Sanna, Daniele, Mulas, Maurizio, Molinu, Maria Giovanna, and Fadda, Angela
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- 2019
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15. Antioxidant and Anticancer Activity of Pericarp Water Extracts of Mediterranean Ancient Chestnut Accessions.
- Author
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Spissu, Ylenia, Molinu, Maria Giovanna, D'hallewin, Guy, Sanna, Giulia, Serra, Gavina Rita, Muroni, Antonella, and Barberis, Antonio
- Subjects
CHESTNUT ,CASTANEA ,PERICARP ,ANTINEOPLASTIC agents ,CHARGE exchange ,BREAST ,GERMPLASM ,PLANT germplasm - Abstract
The residue of chestnut processing generates a large amount of waste material, a resource not adequately exploited. The antioxidant and antitumoral properties of cold and hot water extracts from discarded pericarp of four chestnut Sardinian accessions and one marron variety were studied. The antioxidant capacity of the extracts was determined by spectrophotometric and electrochemical tests. The 1,1-diphenyl-2-pic-rylhydrazyl (DPPH) and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) results were highly correlated with each other; likewise, a good correlation was found between Ferric Reducing Antioxidant Power (FRAP) and cyclic voltammetry (CV) values, both based on the direct transfer of electrons. The antiproliferative effect on normal cells (fibroblasts), and on colon (RKO and SW48) and breast (MCF7) cancer cells was evaluated. Additionally, this paper marks the first application of chestnut extracts to investigate their effects on melanoma (B16F10) cells. The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test demonstrated that temperature and different extraction times significantly influenced the growth of cells, both normal and tumor. The fibroblast growth was significantly inhibited by moderate doses of cold extracts, while the GI
50 values calculated for hot extracts were high, regardless of the accession or cultivar. An even more marked inhibitory action of the cold extracts was observed both on the growth of RKO and SW48 cells and on B16F10 melanoma cells. Otherwise, an extract concentration, both cold and hot, of no less than 243 µg mL−1 is required to achieve a 50% inhibition of MCF7 cell growth. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
16. Il passato remoto irregolare in sardo
- Author
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Molinu, Lucia, primary
- Published
- 2020
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17. Antioxidant Contents in a Mediterranean Population of Plantago lanceolata L. Exploited for Quarry Reclamation Interventions
- Author
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Federico Sanna, Giovanna Piluzza, Giuseppe Campesi, Maria Giovanna Molinu, Giovanni Antonio Re, and Leonardo Sulas
- Subjects
plantain ,multiple uses ,phenolic compounds ,verbascoside ,seasonal variations ,Botany ,QK1-989 - Abstract
Plantago lanceolata L. (plantain) is an interesting multipurpose perennial species whose aerial parts are used in herbal medicine due to its precious phytochemicals and are palatable to animals. Moreover, peculiar traits such as drought tolerance, an extended growth season and a deep root system, make plantain a promising pioneer plant for quarry reclamation based on the use of native species. This study evaluated the effects of different environmental conditions and seasons on the accumulation of the bioactive compounds of its aerial organs. An autochthonous plantain population was grown in three locations in Sardinia (Italy). Leaves, peduncles and inflorescences were collected between October 2020 and July 2021. Phenolic contents and antioxidant capacity were determined. The analysis of the individual phenolic compounds was performed using liquid chromatography. In leaves, the content of total phenolics, antioxidant capacity and total flavonoids were significantly influenced by location and season. Total phenolic content ranged from 65 to 240 g gallic acid equivalent kg−1, whereas total flavonoids were from 16 to about 89 g catechin equivalent kg−1. Neochlorogenic, chlorogenic, cryptochlorogenic acids, verbascoside, diosmin and luteolin were identified in the methanolic extracts of leaves, peduncles and inflorescences. Verbascoside was the main antioxidant isolated from plantain extracts. Results evidenced an increasing accumulation pattern of phenolics from vegetative stage to flowering, followed by a decrement towards the seed ripening as well as site-specific differences with amounts of phenolics even 25% higher for same plantain accession.
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- 2022
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18. Chapter 18. Are Sardinian vocatives perfectly regular?
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Floricic, Franck, primary and Molinu, Lucia, additional
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- 2018
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19. Antioxidants in Fruit Fractions of Mediterranean Ancient Pear Cultivars
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Piluzza, Giovanna, primary, Campesi, Giuseppe, additional, D’hallewin, Guy, additional, Molinu, Maria Giovanna, additional, Re, Giovanni Antonio, additional, Sanna, Federico, additional, and Sulas, Leonardo, additional
- Published
- 2023
- Full Text
- View/download PDF
20. Athematic infinitives in Old Sardinian
- Author
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Lucia Molinu
- Published
- 2023
21. Subterranean Clover and Sulla as Valuable and Complementary Sources of Bioactive Compounds for Rainfed Mediterranean Farming Systems
- Author
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Molinu, Maria Giovanna, primary, Sulas, Leonardo, additional, Campesi, Giuseppe, additional, Re, Giovanni Antonio, additional, Sanna, Federico, additional, and Piluzza, Giovanna, additional
- Published
- 2023
- Full Text
- View/download PDF
22. Effect of short heat treatments with a sodium bicarbonate solution on storability of the yellow germoplasm plum ‘Meloni’
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Molinu, M.G., Dore, A., and D’hallewin, G.
- Published
- 2015
23. Bioactive Compounds from Leaves and Twigs of Guayule Grown in a Mediterranean Environment
- Author
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Giovanna Piluzza, Giuseppe Campesi, Maria Giovanna Molinu, Giovanni Antonio Re, and Leonardo Sulas
- Subjects
Parthenium argentatum ,non-rubber byproduct ,phenolic compounds ,industrial crop ,Botany ,QK1-989 - Abstract
Guayule (Parthenium argentatum) is one of the most promising alternatives to produce natural rubber. As the guayule leaves represent a waste byproduct in the rubber extraction process, their exploitation might contribute to the valorization of the whole plant biomass. The specific aim of our study was to determine the antioxidant capacity and the content of phenolic compounds in leaves and twigs of different guayule lines cultivated in a Mediterranean environment. The antioxidant capacity and the contents of phenolic were affected significantly by guayule accession and harvest time. Overall means in twigs represented about 60% of the corresponding leaf values for antioxidant capacity as DPPH (1,1-diphenyl-2-picrylhydrazyl) and not tannic phenolic and about 55% as ABTS (2,2′-azinobis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt), total phenolic, tannic phenolic and total flavonoid contents. Five individual phenolic compounds were identified in methanolic extracts of leaves. Neochlorogenic acid (62.5–174.8 mg g−1 DW) and chlorogenic acid (28.6–41.1 mg g−1 DW) were the most abundant phenolic acids. In addition to the compounds quantified in leaves, cynarin was identified only in twigs and for the first time in guayule biomass. Our results indicate that guayule leaves and twigs represent a rich source of antioxidants for potential applications in fodder, nutraceutical and pharmacological sectors.
- Published
- 2020
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24. Electron Paramagnetic Resonance Spin Trapping of Sunflower and Olive Oils Subjected to Thermal Treatment: Optimization of Experimental and Fitting Parameters
- Author
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Maria Giovanna Molinu, Pierfrancesco Deiana, Angela Fadda, and Daniele Sanna
- Subjects
Materials science ,Spin trapping ,Chemistry (miscellaneous) ,law ,Organic Chemistry ,Analytical chemistry ,Thermal treatment ,Electron paramagnetic resonance ,Sunflower ,Food Science ,Analytical Chemistry ,law.invention - Published
- 2021
25. 5.2 Fonetica, fonologia, prosodia: sincronia
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Molinu, Lucia, primary
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- 2017
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26. 1.1 Storia delle indagini e classificazioni
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Molinu, Lucia, primary and Floricic, Franck, additional
- Published
- 2017
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27. Evolution of monovarietal virgin olive oils as a function of chemical composition and oxidation status.
- Author
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Deiana, Pierfrancesco, Molinu, Maria Giovanna, Dore, Antonio, Culeddu, Nicola, Dettori, Sandro, and Santona, Mario
- Subjects
OLIVE oil ,ORTHOGRAPHIC projection ,DISCRIMINANT analysis ,OXIDATION ,SECOIRIDOIDS - Abstract
Virgin Olive Oil (VOO) shelf life is determined by the varietal-specific chemical composition and principally by the of phenolic composition. The aim of this study was to investigate the changes in fatty acid profile, phenolic composition, and quality parameters of nine Italian monovarietal VOOs obtained under the same pedoclimatic, agronomic and technological conditions and stored for 12 months at 15 °C in the dark. The varieties with medium-high concentrations of secoiridoids and balanced values between the individual molecules were those with the highest stability. Orthogonal Projections to Latent Structures (OPLS) regression revealed that oleuropein derivatives and phenolic alcohols had the highest antioxidant activity. OPLS discriminant analysis separated well fresh and stored oils. PV, K270, tyrosol, hydroxytyrosol, and oxidated oleacein were the most effective indicators of VOO ageing. Oleacein and oleocanthal decreased after storage, phenolic alcohols, oleacein and ligstroside aglycon increased. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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28. Branching onsets and segment licensing: the lack of debuccalization or deletion of the muta cum liquida clusters in central Sardinian dialects
- Author
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Lucia Molinu
- Subjects
Binding ,Debuccalization ,Government ,Sardinian Dialects ,Language. Linguistic theory. Comparative grammar ,P101-410 ,Oriental languages and literatures ,PJ - Abstract
Some central Sardinian dialects undergo debuccalization of /f/ and /k/. The clusters /fr/ and /kr/, on the other hand, fail to undergo debuccalization or deletion (Wagner 1984 [1941]; Contini 1987; Molinu 1997). The purpose of this article is to attempt to answer the following questions: why does debuccalization of /f/ and /k/ or /f/ deletion systematically affect the fricative in a simple onset but not when /f/ and /k/ are in a branching onset? Which syllabic and segmental requirements determine the different outcomes of /f/ and /k/? I will focus on Rice’s model (Avery and Rice 1989; Rice and Avery 1991; Rice 1992, 1993, 1994a, 1994b) which makes use of the representation of segments to account for their licensing in a syllabic constituent. Indeed Rice assumes two principles (government and binding) which license the consonants in tautosyllabic or heterosyllabic sequences in structural terms, i.e. on the basis of the segment structure. I will account for the absence of debuccalization in the /fr/ and /kr/ clusters showing that the debuccalization process is blocked or repaired when it violates a principle on the structural relationships that hold within segments of branching onsets.
- Published
- 2017
- Full Text
- View/download PDF
29. Sull’abuso dell’opacità in fonologia: prove dai dialetti italiani
- Author
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Del Puente, Patrizia, Guazzelli, Francesca, Molinu, Lucia, Pisano, Simone, Del Puente, P ( Patrizia ), Guazzelli, F ( Francesca ), Molinu, L ( Lucia ), Pisano, S ( Simone ), Loporcaro, Michele, Del Puente, Patrizia, Guazzelli, Francesca, Molinu, Lucia, Pisano, Simone, Del Puente, P ( Patrizia ), Guazzelli, F ( Francesca ), Molinu, L ( Lucia ), Pisano, S ( Simone ), and Loporcaro, Michele
- Published
- 2020
30. AstraZeneca (AZD1222) COVID‐19 vaccine‐associated adverse drug event: A case report
- Author
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Marco Capassoni, Anna A. Molinu, Sheyda Ketabchi, Felice Galluccio, Serena Guiducci, Riccardo Caramelli, and Angelo Cassisa
- Subjects
2019-20 coronavirus outbreak ,Infectious Diseases ,Coronavirus disease 2019 (COVID-19) ,Adverse drug event ,business.industry ,Virology ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,MEDLINE ,Medicine ,Letters to the Editor ,business ,Letter to the Editor - Published
- 2021
31. Antioxidant Contents in a Mediterranean Population of Plantago lanceolata L. Exploited for Quarry Reclamation Interventions
- Author
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Sanna, Federico, primary, Piluzza, Giovanna, additional, Campesi, Giuseppe, additional, Molinu, Maria Giovanna, additional, Re, Giovanni Antonio, additional, and Sulas, Leonardo, additional
- Published
- 2022
- Full Text
- View/download PDF
32. Antimicrobial activities of virgin olive oils in vitro and on lettuce from pathogen-inoculated commercial quick salad bags
- Author
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Fancello, Francesco, primary, Multineddu, Chiara, additional, Santona, Mario, additional, Molinu, Maria Giovanna, additional, Zara, Giacomo, additional, Dettori, Sandro, additional, Deiana, Pierfrancesco, additional, and Zara, Severino, additional
- Published
- 2022
- Full Text
- View/download PDF
33. Evolution of monovarietal virgin olive oils as a function of chemical composition and oxidation status
- Author
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Deiana, Pierfrancesco, primary, Molinu, Maria Giovanna, additional, Dore, Antonio, additional, Culeddu, Nicola, additional, Dettori, Sandro, additional, and Santona, Mario, additional
- Published
- 2022
- Full Text
- View/download PDF
34. Préstamos en asturiano: Estudio morfo-fonológico
- Author
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Lucia Molinu
- Subjects
060201 languages & linguistics ,030507 speech-language pathology & audiology ,03 medical and health sciences ,0602 languages and literature ,06 humanities and the arts ,Sociology ,0305 other medical science ,Humanities ,Epenthesis - Abstract
asturianuNa nuesa contribucion presentaremos un estudiu sobro l’adautacion de les consonantes nos emprestamos n’asturianu. Fadremos por analizar el comportamientu fonoloxicu de les consonantes de los emprestamos dende un puntu de vista silabicu. Naguamos por describir mas precisamente’l so grau d’adautacion en rellacion a les restricciones prosodiques que rixen la cadarma silabica d’esta llingua y facer comparanza de los resultaos con otros idiomes romanicos. El casu del asturianu dexaranos reflexonar tamien sobro los problemes y les cuestiones que se planteguen davezu na lliteratura dedicada a l’adautacion de los emprestamos: ?como se produz l’adautacion d’un emprestamu nuna llingua? ?Hai preferencies universales pa dellos tipos de reparacion sobro otros, por casu la epentesis sobro la supresion? ?Han tratase los emprestamos de mou uniforme dientro’l lexicu o tan suxetos a parametros especiales acordies col so grau d’inxerimientu? EnglishIn our contribution we will present a study on the adaptation of consonants in Asturian loans. We will try to analyze the phonological behavior of consonants in loans from a syllabic point of view. We want more precisely to describe their degree of adaptation in relation to the prosodic restrictions that govern the syllabic structure of this language and to compare the results with other Romance varieties. The case of the Asturian will also allow us to reflect on the problems and questions that frequently arise in the literature dedicated to the adaptation of loans: how does the adaptation of a loan in one language take place? Are there universal preferences for certain types of reparation over others, for example, epenthesis over deletion? Should loans be treated uniformly within the lexicon or are they subject to special parameters depending on their degree of integration?
- Published
- 2020
35. Evolution of monovarietal virgin olive oils as a function of chemical composition and oxidation status
- Author
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Pierfrancesco Deiana, Maria Giovanna Molinu, Antonio Dore, Nicola Culeddu, Sandro Dettori, and Mario Santona
- Subjects
variety ,Organic Chemistry ,OPLS ,shelf life ,Plant Science ,oleuropein aglycon ,oxidation stability ,Olea europaea ,Biochemistry ,oleocanthal ,Analytical Chemistry - Abstract
Virgin Olive Oil (VOO) shelf life is determined by the varietal-specific chemical composition and principally by the of phenolic composition. The aim of this study was to investigate the changes in fatty acid profile, phenolic composition, and quality parameters of nine Italian monovarietal VOOs obtained under the same pedoclimatic, agronomic and technological conditions and stored for 12 months at 15 degrees C in the dark. The varieties with medium-high concentrations of secoiridoids and balanced values between the individual molecules were those with the highest stability. Orthogonal Projections to Latent Structures (OPLS) regression revealed that oleuropein derivatives and phenolic alcohols had the highest antioxidant activity. OPLS discriminant analysis separated well fresh and stored oils. PV, K270, tyrosol, hydroxytyrosol, and oxidated oleacein were the most effective indicators of VOO ageing. Oleacein and oleocanthal decreased after storage, phenolic alcohols, oleacein and ligstroside aglycon increased.
- Published
- 2022
- Full Text
- View/download PDF
36. La place du Sarde dans la Romania et la Revue des langues romanes
- Author
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Molinu, Lucia, Floricic, Franck, BCL, équipe Dialectologie et Linguistique formelle, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), and Gilda Caiti-Russo
- Subjects
[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
37. Les désignations romanes de« scier »
- Author
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Molinu, Lucia, Brun-Trigaud, Guylaine, BCL, équipe Dialectologie et Linguistique formelle, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)
- Subjects
[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
38. Effect of short heat treatments with a sodium bicarbonate solution on storability of the yellow germoplasm plum 'Meloni'
- Author
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Maria Giovanna Molinu, A. Dore, and G. D'hallewin
- Subjects
decay control ,GRAS compounds ,Penicillium expansum ,Biology (General) ,QH301-705.5 ,Botany ,QK1-989 - Abstract
The behavior of a Sardinian plum, cv. Meloni, was investigated with regard to short-heat treatments at 20, 50, 55 or 60°C in water with 0 or 2% NaHCO3 (SBC) for 0, 15, 30, 45 or 60 seconds. Fruits were stored for one month at 5°C and 95% RH followed by a simulated marketing period (SMP) at 20°C and 80% RH for six days. Quality and decay percentage were monitored. In addition, fruits were artificially inoculated with P. expansum and stored for 10 days at 25°C and 95% RH. Compared to the control, all short-heat dip treatments lowered the degree of decay, and the efficacy was positively correlated with temperature and treatment duration. The use of SBC increased the efficacy of decay control and the best results were attained at 55 and 60°C. Heat treatments increased levels of total flavonoids and antioxidant activity after SMP. None of the heat treatments induced rind damage (browning or discoloration), but the overall appearance decreased significantly when fruit was treated at 55 or 60°C for 60 s after SMP. Scanning electron microscopy (SEM) observations showed that treatments at 55 and 60°C with SBC cause damage and loss of cuticular wax on fruit surface.
- Published
- 2015
- Full Text
- View/download PDF
39. IRF2BPL nonsense mutation associated with adult onset myoclonic epilepsy and cerebellar ataxia: A case report
- Author
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Pisano, Stefano, Melis, Marta, Figorilli, Michela, Muroni, Antonella, Polizzi, Lorenzo, Molinu, Claudia, Perretti, Carlo, and Defazio, Giovanni
- Published
- 2021
- Full Text
- View/download PDF
40. Impact of C9ORF72 and TARDBP-43 mutations in a Sardinian cohort of frontotemporal dementia patients
- Author
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Piga, Giuseppe, Floris, Gianluca, Borghero, Giuseppe, Primicerio, Giulia, Molinu, Claudia, Fadda, Laura, and Defazio, Giovanni
- Published
- 2021
- Full Text
- View/download PDF
41. Use of High-Intensity Ultrasound to Increase the Efficiency of Imazalil in Postharvest Storage of Citrus Fruits
- Author
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Dore, Antonio, Molinu, Maria Giovanna, Venditti, Tullio, and D’hallewin, Guy
- Published
- 2013
- Full Text
- View/download PDF
42. Italian Guidelines in patch testing - Adapted from the European Society of Contact Dermatitis (ESCD)
- Author
-
Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., Venturini, M., Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Stingeni, L., Bianchi, L., Hansel, K., Corazza, M., Gallo, R., Guarneri, F., Patruno, C., Rigano, L., Romita, P., Pigattoatt, P. D., Calzavara-Pintoton, P., Agostinelli, S., Albertazzi, D., Angelini, G., Angerosa, F., Arigliano, P. L., Assalve, D., Ayala, F., Bellonifortina, A., Berta, M., Biale, C., Biasini, I., Boccaletti, V., Bonamonte, D., Borghi, A., Brambilla, L., Bressan, M., Bruno, A., Caccavale, S., Calogiuri, G., Cannavò, S. P., Carugno, A., Cataldi, I., Chiarelli, G., Chiesa, A., Cirla, A. M., Cossutta, M., Cova, L. M., Cristaudo, A., Dalcan-Ton, M., Damiani, G., Danese, P., Desalvo, V., Fantini, C., Ferrucci, S. M., Flori, M. L., Fontana, E., Foti, C., Francalanci, S., Frasin, L. A., Gola, M., Gravante, M., Guastaferro, D., Ingordo, V., Lauriola, M. M., Leghissa, P., Lisi, P., Lombardi, P., Lorenzini, M., Magrini, L., Marone, G., Martina, E., Mascagni, P., Matteinichiari, M., Meligeni, L., Melino, M., Milanesi, N., Molinu, A. A., Monfrecola, G., Morelli, P., Motolese, A., Musumeci, M. L., Napolitano, M., Nasca, M. R., Paganini, P., Papini, M., Pasolini, G., Peroni, A., Peserico, A., Piras, V., Pugliese, A., Raponi, F., Raviolo, P. D., Rebora, A., Recchia, G. P., Riva, F., Rossi, M., Ruggieri, M., Saggiorato, F., Sartorelli, P., Schena, D., Schettino, A., Spano, G., Stinchi, C., Taddei, L., Tasin, L., Tramontana, M., Valsecchi, R. H., Vascellaro, A., and Venturini, M.
- Abstract
Patch testing is the standard procedure used to diagnose allergic contact dermatitis. It is an in-vivo test, which reproduces the reaction to a contact allergen. This in-vivo test aims to reproduce the elicitation phase of allergic contact dermatitis and is performed applying allergens under occlusion on the skin under standardized conditions. These guidelines for the best practice in performing patch test have been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Society of Contact Dermatitis (ESCD) and on the basis of the SIDAPA guidelines.
- Published
- 2019
43. Italian Guidelines in Patch Testing - adapted from the European Society of Contact Dermatitis (ESCD)
- Author
-
Stingeni, Luca, Bianchi, Leonardo, Hansel, Katharina, Corazza, Monica, Gallo, Rosella, Guarneri, Fabrizio, Patruno, Cataldo, Rigano, Luigi, Romita, Paolo, Pigatto, Paolo D, Calzavara-Pinton, Piergiacomo, Agostinelli, D, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, Pl, Assalve, D, Ayala, F, Belloni, Fortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, Sp, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, Am, Cossutta, M, Cova, Lm, Cristaudo, A, Dal Canton, M, Damiani, G, Danese, P, De Salvo, V, Fantini, C, Ferrucci, Sm, Flori, Ml, Fontana, E, Foti, C, Francalanci, S, Frasin, La, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, Mm, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteini, Chiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, Aa, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, Ml, Napolitano, M, Nasca, Mr, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, Pd, Rebora, A, Recchia, Gp, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, Rh, Vascellaro, A, Venturini, M, Vincenzi, C, Virgili, A, Zucca, M, Stingeni, L, Bianchi, L, Hansel, K, Corazza, M, Gallo, R, Guarneri, F, Patruno, C, Rigano, L, Romita, P, Pigattoatt, P, Calzavara-Pintoton, P, Agostinelli, S, Albertazzi, D, Angelini, G, Angerosa, F, Arigliano, P, Assalve, D, Ayala, F, Bellonifortina, A, Berta, M, Biale, C, Biasini, I, Boccaletti, V, Bonamonte, D, Borghi, A, Brambilla, L, Bressan, M, Bruno, A, Caccavale, S, Calogiuri, G, Cannavò, S, Carugno, A, Cataldi, I, Chiarelli, G, Chiesa, A, Cirla, A, Cossutta, M, Cova, L, Cristaudo, A, Dalcan-Ton, M, Damiani, G, Danese, P, Desalvo, V, Fantini, C, Ferrucci, S, Flori, M, Fontana, E, Foti, C, Francalanci, S, Frasin, L, Gola, M, Gravante, M, Guastaferro, D, Ingordo, V, Lauriola, M, Leghissa, P, Lisi, P, Lombardi, P, Lorenzini, M, Magrini, L, Marone, G, Martina, E, Mascagni, P, Matteinichiari, M, Meligeni, L, Melino, M, Milanesi, N, Molinu, A, Monfrecola, G, Morelli, P, Motolese, A, Musumeci, M, Napolitano, M, Nasca, M, Paganini, P, Papini, M, Pasolini, G, Peroni, A, Peserico, A, Piras, V, Pugliese, A, Raponi, F, Raviolo, P, Rebora, A, Recchia, G, Riva, F, Rossi, M, Ruggieri, M, Saggiorato, F, Sartorelli, P, Schena, D, Schettino, A, Spano, G, Stinchi, C, Taddei, L, Tasin, L, Tramontana, M, Valsecchi, R, Vascellaro, A, Venturini, M, Pigatto, Pd, Calzavara-Pinton, P, 'Skin Allergy' group of SIDeMaST and 'SIDAPA' (Agostinelli, D, Arigliano, Pl, Belloni Fortina, A, Cannavò, Sp, Cirla, Am, Cova, Lm, Dal Canton, M, De Salvo, V, Ferrucci, Sm, Flori, Ml, Frasin, La, Lauriola, Mm, Matteini Chiari, M, Molinu, Aa, Musumeci, Ml, Nasca, Mr, Raviolo, Pd, Recchia, Gp, Valsecchi, Rh, Vincenzi, C, Virgili, A, and Zucca, M).
- Subjects
Dermatitis, contact, Guideline, Patch tests ,medicine.medical_specialty ,Allergic Contact ,Socio-culturale ,Dermatitis ,Dermatology ,Patch tests ,Guideline ,contact ,Patch test ,Patch testing ,Standard procedure ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,Dermatitis, contact ,Allergens ,Dermatitis, Allergic Contact ,Humans ,Italy ,Patch Tests ,medicine ,Allergic contact dermatitis ,business.industry ,Contact dermatitis ,medicine.disease ,Test (assessment) ,Family medicine ,business - Abstract
Patch testing is the standard procedure used to diagnose allergic contact dermatitis. It is an in-vivo test, which reproduces the reaction to a contact allergen. This in-vivo test aims to reproduce the elicitation phase of allergic contact dermatitis and is performed applying allergens under occlusion on the skin under standardized conditions. These guidelines for the best practice in performing patch test have been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Society of Contact Dermatitis (ESCD) and on the basis of the SIDAPA guidelines.
- Published
- 2019
44. Tra etimologia romanza e dialettologia. Studi in onore di Franco Fanciullo
- Author
-
Molinu, Lucia, Guazzelli, Francesca, Del Puente, Patrizia, PISANO, Simone, BCL, équipe Dialectologie et Linguistique formelle, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Patrizia Del Puente, Francesca Guazzelli, and Lucia Molinu e Simone Pisano
- Subjects
[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2020
45. Contraintes et variation en sarde et ailleurs
- Author
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Molinu, Lucia, BCL, équipe Dialectologie et Linguistique formelle, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Université Côte d’Azur, and Diana Passino
- Subjects
romance languages ,dialectology ,phonology ,Sardinian ,morphologie ,contraintes ,morphology ,langues romanes ,phonologie ,dialectologie ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,constraints ,sarde - Published
- 2021
46. The athematic infinitives in old Sardinian
- Author
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Molinu, Lucia, BCL, équipe Dialectologie et Linguistique formelle, Bases, Corpus, Langage (UMR 7320 - UCA / CNRS) (BCL), Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)
- Subjects
Sardinian ,Distributed Morphology ,[SHS.LANGUE]Humanities and Social Sciences/Linguistics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2021
47. Chromosomal Instability, Aneuploidy, and Gene Mutations in Human Sporadic Colorectal Adenomas
- Author
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Walter Giaretti, Silvia Molinu, Jenny Ceccarelli, and Claudia Prevosto
- Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 ,Cytology ,QH573-671 - Abstract
Whether in vivo specific gene mutations lead to chromosomal instability (CIN) and aneuploidy or viceversa is so far not proven. We hypothesized that aneuploidy among human sporadic colorectal adenomas and KRAS2 and APC mutations were not independent. Additionally, we investigated if 1p34–36 deletions by dual target FISH were associated with aneuploidy. Among 116 adenomas, 29 were DNA aneuploid by flow cytometry (25%) and 29 were KRAS2 mutated (25%). KRAS2 mutations were associated with aneuploidy (P=0.02). However, while G–C and G–T transversions were strongly associated with DNA aneuploidy (P=0.007), G–A transitions were not. Within a second series of 61 adenomas, we found, instead, that APC mutational status and aneuploidy by flow cytometry were not associated. However, a statistically significant association was found with specific APC mutations, i.e., occurring in the mutation cluster region (MCR, codons 1200–1500) or downstream (P=0.016). Finally, the correlation of 1p34–36 deletions with flow cytometric and FISH detected aneuploidy was also significant (P=0.01). Specific KRAS2 and APC mutations and loss of genes in the 1p34–36 region appear associated with aneuploidy suggesting that these events are not independent and may cooperate in inducing human sporadic colorectal adenomas. A cause effect relationship between gene mutations and aneuploidy remains, however, to be demonstrated.
- Published
- 2004
- Full Text
- View/download PDF
48. Hikikomori e anoressia: famiglie e identità fragili a confronto
- Author
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Chiara Molinu
- Subjects
Mechanical Engineering ,Energy Engineering and Power Technology ,Management Science and Operations Research - Published
- 2019
49. Oxidative stability of plant hydroalcoholic extracts assessed by EPR spin trapping under forced ageing conditions: A myrtle case study
- Author
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Maria Giovanna Molinu, Angela Fadda, Maurizio Mulas, and Daniele Sanna
- Subjects
Antioxidant ,Free Radicals ,medicine.medical_treatment ,Radical ,01 natural sciences ,Analytical Chemistry ,law.invention ,Hydroxyl radical scavenging activity ,chemistry.chemical_compound ,0404 agricultural biotechnology ,law ,medicine ,Electron paramagnetic resonance ,Oxidative stability ,Ethanol ,Chromatography ,Myrtle extracts ,Hydroxyl Radical ,Plant Extracts ,010401 analytical chemistry ,Extraction (chemistry) ,Electron Spin Resonance Spectroscopy ,04 agricultural and veterinary sciences ,General Medicine ,Phenolic acid ,040401 food science ,Myrtus ,0104 chemical sciences ,Oxidative Stress ,chemistry ,Nitrogen Oxides ,Spin Labels ,Hydroxyl radical ,EPR ,Spin Trapping ,Food Science ,Ellagic acid - Abstract
The oxidative stability of myrtle hydroalcoholic extracts was measured, over storage time, with the EPR spin trapping method under forced ageing conditions. The extracts were prepared with 150 and 300 g l−1 of berries and extraction media with ethanol ranging from 60 to 90%. Two radicals were detected: the PBN–1-hydroxyethyl adduct and the tert-butyl aminoxyl radical. A dimensionless parameter (Ω) calculated on the basis of the lag time, the rate of formation and concentration of the radical species was used to estimate the extracts’ oxidative stability. Ω was strongly influenced by the extraction medium, being lower in extracts with ethanol 60%, and by the time of storage. An inverse correlation was calculated between Ω and ellagic acid concentration, thus suggesting the role of this phenolic acid in the antioxidant properties of the extracts. The radical scavenging activity of the extracts against the hydroxyl radical was also measured.
- Published
- 2019
50. Chapter 4 - The chemical composition of Italian virgin olive oils
- Author
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Deiana, Pierfrancesco, Filigheddu, Maria Rosaria, Dettori, Sandro, Culeddu, Nicola, Dore, Antonio, Molinu, Maria Giovanna, and Santona, Mario
- Published
- 2021
- Full Text
- View/download PDF
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