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Acute myeloid leukemia (AML) is a highly aggressive cancer form that affects myeloid cells, leading to the excessive growth of immature white blood cells (WBCs) in both bone marrow and peripheral blood. Timely AML detection is crucial for effective treatment and patient well-being. Currently, AML diagnosis relies on the manual recognition of immature WBCs through peripheral blood smear analysis, which is time-consuming, prone to errors, and subject to inter-observers' variation. This study aimed to develop a computer-aided diagnostic framework for AML, called "CAE-ResVGG FusionNet", that precisely identifies and classifies immature WBCs into their respective subtypes. The proposed framework leverages an integrated approach, by combining a convolutional autoencoder (CAE) with finely tuned adaptations of the VGG19 and ResNet50 architectures to extract features from CAE-derived embeddings. The process begins with a binary classification model distinguishing between mature and immature WBCs followed by a multiclassifier further classifying immature cells into four subtypes: myeloblasts, monoblasts, erythroblasts, and promyelocytes. The CAE-ResVGG FusionNet workflow comprises four primary stages, including data preprocessing, feature extraction, classification, and validation. The preprocessing phase involves applying data augmentation methods using geometric transformations and synthetic image generation using the CAE to address imbalance in the WBC distribution. Feature extraction involves image embedding and transfer learning, where CAE-derived image representations are used by a custom integrated model of VGG19 and ResNet50 pretrained models. The classification phase employs a weighted ensemble approach that leverages VGG19 and ResNet50, where the optimal weighting parameters are selected using a grid search. The model performance was assessed during the validation phase using the overall accuracy, precision, and sensitivity, while the area under the receiver characteristic curve (AUC) was used to evaluate the model's discriminatory capability. The proposed framework exhibited notable results, achieving an average accuracy of 99.9%, sensitivity of 91.7%, and precision of 98.8%. The model demonstrated exceptional discriminatory ability, as evidenced by an AUC of 99.6%. Significantly, the proposed system outperformed previous methods, indicating its superior diagnostic ability., Competing Interests: ☒ The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. ☐ The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:, (© 2024 The Authors.)

Anterior cruciate ligament (ACL) tears are a common knee injury that can have serious consequences and require medical intervention. Magnetic resonance imaging (MRI) is the preferred method for ACL tear diagnosis. However, manual segmentation of the ACL in MRI images is prone to human error and can be time-consuming. This study presents a new approach that uses deep learning technique for localizing the ACL tear region in MRI images. The proposed multi-scale guided attention-based context aggregation (MGACA) method applies attention mechanisms at different scales within the DeepLabv3+ architecture to aggregate context information and achieve enhanced localization results. The model was trained and evaluated on a dataset of 917 knee MRI images, resulting in 15265 slices, obtaining state-of-the-art results with accuracy scores of 98.63%, intersection over union (IOU) scores of 95.39%, Dice coefficient scores (DCS) of 97.64%, recall scores of 97.5%, precision scores of 98.21%, and F1 Scores of 97.86% on validation set data. Moreover, our method performed well in terms of loss values, with binary cross entropy combined with Dice loss (BCE_Dice_loss) and Dice_loss values of 0.0564 and 0.0236, respectively, on the validation set. The findings suggest that MGACA provides an accurate and efficient solution for automating the localization of ACL in knee MRI images, surpassing other state-of-the-art models in terms of accuracy and loss values. However, in order to improve robustness of the approach and assess its performance on larger data sets, further research is needed., Competing Interests: The authors declare there are no competing interests., (©2023 Awan et al.)

The current methods of classifying plant disease images are mainly affected by the training phase and the characteristics of the target dataset. Collecting plant samples during different leaf life cycle infection stages is time-consuming. However, these samples may have multiple symptoms that share the same features but with different densities. The manual labelling of such samples demands exhaustive labour work that may contain errors and corrupt the training phase. Furthermore, the labelling and the annotation consider the dominant disease and neglect the minor disease, leading to misclassification. This paper proposes a fully automated leaf disease diagnosis framework that extracts the region of interest based on a modified colour process, according to which syndrome is self-clustered using an extended Gaussian kernel density estimation and the probability of the nearest shared neighbourhood. Each group of symptoms is presented to the classifier independently. The objective is to cluster symptoms using a nonparametric method, decrease the classification error, and reduce the need for a large-scale dataset to train the classifier. To evaluate the efficiency of the proposed framework, coffee leaf datasets were selected to assess the framework performance due to a wide variety of feature demonstrations at different levels of infections. Several kernels with their appropriate bandwidth selector were compared. The best probabilities were achieved by the proposed extended Gaussian kernel, which connects the neighbouring lesions in one symptom cluster, where there is no need for any influencing set that guides toward the correct cluster. Clusters are presented with an equal priority to a ResNet50 classifier, so misclassification is reduced with an accuracy of up to 98%.

Recent advancements in artificial intelligence (AI) have led to numerous medical discoveries. The field of computer vision (CV) for medical diagnosis has received particular attention. Using images of peripheral blood (PB) smears, CV has been utilized in hematology to detect acute leukemia (AL). Significant research has been undertaken in the area of AL diagnosis automation in order to deliver an accurate diagnosis. This study addresses the morphological classification of atypical white blood cells (WBCs), including immature WBCs and atypical lymphocytes, in acute myeloid leukemia (AML), as observed in peripheral blood (PB) smear images. The purpose of this work is to build a classification model for atypical AML WBCs based on their distinctive features. Using a hybrid model based on geometric transformation (GT) and a deep convolutional autoencoder (DCAE), this work provides a novel technique in the field of AI for resolving the issue of imbalanced distribution of WBCs in blood samples, nicknamed the "GT-DCAE WBC augmentation model". In addition, to extract context-free atypical WBC features, this study develops a stable learning paradigm by incorporating WBC segmentation into deep learning. In order to classify atypical WBCs into eight distinct subgroups, a hybrid multiclassification model termed the "two-stage DCAE-CNN atypical WBC classification model" (DCAE-CNN) was developed. The model achieved an average accuracy of 97%, a sensitivity of 97%, and a precision of 98%. Overall and by class, the model's discriminating abilities were exceptional, with an AUC of 99.7% and a class-wise range of 80% to 100%.

COVID-19 was first discovered in December 2019 in Wuhan. There have been reports of thousands of illnesses and hundreds of deaths in almost every region of the world. Medical images, when combined with cutting-edge technology such as artificial intelligence, have the potential to improve the efficiency of the public health system and deliver faster and more reliable findings in the detection of COVID-19. The process of developing the COVID-19 diagnostic system begins with image accusation and proceeds via preprocessing, feature extraction, and classification. According to literature review, several attempts to develop taxonomies for COVID-19 detection using image processing methods have been introduced. However, most of these adhere to a standard category that exclusively considers classification methods. Therefore, in this study a new taxonomy for the early stages of COVID-19 detection is proposed. It attempts to offer a full grasp of image processing in COVID-19 while considering all phases required prior to classification. The survey concludes with a discussion of outstanding concerns and future directions.

Modalities like MRI give information about organs and highlight diseases. Organ information is visualized in intensities. The segmentation method plays an important role in the identification of the region of interest (ROI). The ROI can be segmented from the image using clustering, features, and region extraction. Segmentation can be performed in steps; firstly, the region is extracted from the image. Secondly, feature extraction performed, and better features are selected. They can be shape, texture, or intensity. Thirdly, clustering segments the shape of tumor, tumor has specified shape, and shape is detected by feature. Clustering consists of FCM, K-means, FKM, and their hybrid. To support the segmentation, we conducted three studies (region extraction, feature, and clustering) which are discussed in the first line of this review paper. All these studies are targeting MRI as a modality. MRI visualization proved to be more accurate for the identification of diseases compared with other modalities. Information of the modality is compromised due to low pass image. In MRI Images, the tumor intensities are variable in tumor areas as well as in tumor boundaries., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2022 Khurram Ejaz et al.)

In recent times, knee joint pains have become severe enough to make daily tasks difficult. Knee osteoarthritis is a type of arthritis and a leading cause of disability worldwide. The middle of the knee contains a vital portion, the anterior cruciate ligament (ACL). It is necessary to diagnose the ACL ruptured tears early to avoid surgery. The study aimed to perform a comparative analysis of machine learning models to identify the condition of three ACL tears. In contrast to previous studies, this study also considers imbalanced data distributions as machine learning techniques struggle to deal with this problem. The paper applied and analyzed four machine learning classification models, namely, random forest (RF), categorical boosting (Cat Boost), light gradient boosting machines (LGBM), and highly randomized classifier (ETC) on the balanced, structured dataset of ACL. After oversampling a hyperparameter adjustment, the above four models have achieved an average accuracy of 95.72%, 94.98%, 94.98%, and 98.26%. There are 2070 observations and eight features in the collection of three diagnosis ACL classes after oversampling. The area under curve value was approximately 0.998, respectively. Experiments were performed using twelve machine learning algorithms with imbalanced and balanced datasets. However, the accuracy of the imbalanced dataset has remained under 76% for all twelve models. After oversampling, the proposed model may contribute to the investigation of ACL tears on magnetic resonance imaging and other knee ligaments efficiently and automatically without involving radiologists., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2022 Mazhar Javed Awan et al.)