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6 results on '"Mohammed Markouk"'

1. Characterization of the Phytochemical Composition and Bioactivities of Anacyclus maroccanus Ball. and Anacyclus radiatus Loisel Aerial Parts: Preliminary Evidence for the Possible Development of Moroccan Plants

Author

Saida Sissi, Silvia Di Giacomo, Claudio Ferrante, Paola Angelini, Alberto Macone, Anna Maria Giusti, Chiara Toniolo, Annabella Vitalone, Aghraz Abdellah, Mustapha Larhsini, Luigi Menghini, Mohammed Markouk, Gabriela Mazzanti, and Antonella Di Sotto

Subjects
phenolics, hypoglycemic activity, α-glucosidase, antiglycation activity, chelating activity, advanced glycation end products, Organic chemistry, QD241-441
Abstract

In the present study, the phytochemical composition and bioactivities of A. maroccanus (AM) and A. radiatus (AR), two ecotypes collected in the Demnate road and Essaouira regions, respectively, were studied to highlight a pharmacological interest and to enable possible pharmaceutical development. To this end, methanolic and ethyl acetate extracts were prepared for each ecotype by fractionation; next, their phytochemical composition was evaluated by spectrophotometric and chromatographic analysis. Moreover, in line with the available evidence for Anacyclus spp. and their traditional use, a screening of bioactivities, including antioxidant, hypoglycemic, antiglycative, chelating, and antibacterial activities, was performed. The extracts were characterized by high amounts of polyphenols, tannins, and flavonoids, especially in the methanolic extracts; these samples were also enriched in carotenoids despite a lower chlorophyll content. Chlorogenic acid and rutin were the major identified compounds. The extracts also showed interesting hypoglycemic, antiglycative, and antibacterial properties, although with differences in efficacy and potency. Present results provide more scientific basis to the ethnopharmacological uses of Anacyclus spp. and suggest a further interest in AM and AR ecotypes as natural sources of bioactive compounds and/or phytocomplexes for possible pharmaceutical and nutraceutical developments.

Published
2022
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4. Characterization of the Phytochemical Composition and Bioactivities of

Author

Saida, Sissi, Silvia, Di Giacomo, Claudio, Ferrante, Paola, Angelini, Alberto, Macone, Anna Maria, Giusti, Chiara, Toniolo, Annabella, Vitalone, Aghraz, Abdellah, Mustapha, Larhsini, Luigi, Menghini, Mohammed, Markouk, Gabriela, Mazzanti, and Antonella, Di Sotto

Subjects
Flavonoids, Morocco, Plant Extracts, Phytochemicals, Polyphenols, Microbial Sensitivity Tests, Asteraceae, Plant Components, Aerial, Tannins, Antioxidants, Anti-Bacterial Agents
Abstract

In the present study, the phytochemical composition and bioactivities of

Published
2021

5. List of Contributors

Author

Ashish K. Agrawal, Iqbal Ahmad, Mohd Sajjad Ahmad Khan, Malika Ait-Sidi-Brahim, Saleh Bakheet Al-Ghamdi, Nasser A. Al-Shabib, Mohd Musheer Altaf, Abdullah Safar Althubiani, Firoz Ahmad Ansari, Farrukh Aqil, Jamal M. Arif, Anwesha Banerjee, Rathindranath Baral, Ushasi Bhaumik, Priyanka Bhowmik, Anamika Bose, Angela I. Calderon, Swaranjit Singh Cameotra, Debprasad Chattopadhyay, Puneet Singh Chauhan, Apurba Das, Jyoti Das, Anupam Dhasmana, Deepak Dwivedi, S. Farooq, Govind Gupta, Ramesh Gupta, Debaki Ranjan Howlader, Fohad Mabood Husain, Huma Jafri, Roshan Jahan, Meenu Kalkal, Altaf Khan, Mohammad Shavez Khan, Mohd Shahnawaz Khan, Rais Ahmad Khan, V.K. Khanna, Hemanta Koley, Mustapha Larhsini, Temitope O. Lawal, Mohtashim Lohani, Gail B. Mahady, Ananya Das Mahapatra, Hesham A. Malak, Mohammed Markouk, Zafar Mehmood, Sankalp Misra, Debashis Mitra, Radha Munagala, Arathi Nair, Saba Noor, Durbadal Ojha, A. Pandey, A.B. Pant, Faizan Abul Qais, Sana Raza, Bhaskar Saha, Mohammad Sajid, null Samreen, Sudhanshu Sharma, Vivek Kumar Sharma, Brahma N. Singh, A. Srivastava, P. Srivastava, Anjali Tripathi, Parul Tripathi, Jay Trivedi, and Sheila M. Wicks

Published
2019

6. Chemical Composition, Antioxidant, Antimicrobial and Insecticidal Activities of Essential Oil from a Moroccan Endemic Plant: Bubonium imbricatum

Author

Abdellah, Aghraz, Jürgen, Wanner, Erich, Schmidt, Loubna, Aitdra, Malika, Aitsidibrahim, Nurhayat, Tabanca, Ali, Abbas, Lahcen, Hassani, Mohammed, Markouk, Leopold, Jirovetz, and Mustapha, Larhsini

Subjects
Insecticides, Bacteria, Microbial Sensitivity Tests, Asteraceae, Antioxidants, Morocco, Anti-Infective Agents, Aedes, Larva, Oils, Volatile, Animals, Plant Oils, Biological Assay, Candida
Abstract

The chemical composition, antioxidant, antimicrobial and insecticidal properties of essential oil obtained by hydro-distillation from Bubonium imbricatum Cav. have been investigated. The essential oil of aerial parts was analyzed by GC-FID and GC-MS. A total of 63 compounds were identified representing more than 82% of the oil. The major components were cis-chrysanthenyl acetate (31.2%) and thymol isobutyrate (3.4%). The antioxidant activity was evaluated by the DPPH and reducing power test. The data showed moderate activity compared with the reference compounds. Our results showed strong activity of the investigated oil against all tested microorganisms. The highest antibacterial activity was observed against Bacillus subtilis (inhibition zone= 18 ± 0.21, MIC= 0.18 mg/mL). In general, Gram-positive bacteria were more susceptible than Gram-negative ones. Candida parapsilosis was the most sensitive among the Candida strains tested. LD50 and LD90 values were 33.1 and 53.1 ppm against 1-d-old larvae of Aedes aegypti L.

Published
2018

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