192 results on '"Mohammad, Nur-E-Alam"'
Search Results
2. Optimization of energy management in Malaysian microgrids using fuzzy logic-based EMS scheduling controller
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Mohammad Nur-E-Alam, Tarek Abedin, Nur Aini Samsudin, Jana Petrů, Abdulwasa Bakr Barnawi, Manzoore Elahi M. Soudagar, T. M. Yunus Khan, Muhammad Nasir Bashir, Mohammad Aminul Islam, Boon Kar Yap, and Tiong Sieh Kiong
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Fuzzy logic controller ,Energy management system ,Microgrid ,MATLAB simulink ,Medicine ,Science - Abstract
Abstract The microgrid (MG) faces significant security issues due to the two-way power and information flow. Integrating an Energy Management System (EMS) to balance energy supply and demand in Malaysian microgrids, this study designs a Fuzzy Logic Controller (FLC) that considers intermittent renewable sources and fluctuating demand patterns. FLC offers a flexible solution to energy scheduling effectively assessed by MATLAB/Simulink simulations. The microgrid consists of PV, battery, grid, and load. A Maximum Power Point Tracking (MPPT) controller helps to extract the maximum PV output and manages the power storage by providing or absorbing excess power. System analysis is performed by observing the State of Charge (SoC)of the battery and output power for each source. The grid supplies additional power if the battery and PV fail to meet the load demand. Total Harmonic Distortion (THD) analysis compares the performance of the Proportional-Integral Controller (PIC) and FLC. The results show that the PI controller design reduces the THD in the current signal, while FLC does not reduce the THD of the grid current when used in the EMS. However, FLC offers better control over the battery’s SOC, effectively preventing overcharging and over-discharging. While PI reduces THD, FLC provides superior SOC control in a system comprising PV, battery, grid, and load. The findings demonstrate that the output current is zero when the SOC is higher than 80% or lower than 20%, signifying that no charging or discharging takes place to avoid overcharging and over-discharging. The third goal was accomplished by comparing and confirming that the grid current’s THD for the EMS designed with both the PI Controller and the FLC is maintained below 5%, following the IEEE 519 harmonic standard, using the THD block in MATLAB Simulink. This analysis highlights FLC’s potential to address demand-supply mismatches and renewable energy variability, which is crucial for optimizing microgrid performance.
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- 2025
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3. Au-Decorated Ti3C2 MXene Sensor for Enhanced Detection of Gaseous Toxins (CO, COCl2, H2S, NH3, NO2): A DFT Study
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Muhammad Huzaifa, Muhammad Shafiq, Nida Ali, Caterina Cocchi, Mohammad Nur-e-Alam, and Zaheer Ul-Haq
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Chemistry ,QD1-999 - Published
- 2024
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4. A hybrid cardiovascular arrhythmia disease detection using ConvNeXt-X models on electrocardiogram signals
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Md. Alamin Talukder, Majdi Khalid, Mohsin Kazi, Nusrat Jahan Muna, Mohammad Nur-e-Alam, Sajal Halder, and Nasrin Sultana
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Arrhythmia detection ,ConvNeXt models ,Data balancing techniques ,SMOTE-TomekLink ,Deep learning in healthcare ,Electrocardiogram classification ,Medicine ,Science - Abstract
Abstract Cardiovascular arrhythmia, characterized by irregular heart rhythms, poses significant health risks, including stroke and heart failure, making accurate and early detection critical for effective treatment. Traditional detection methods often struggle with challenges such as imbalanced datasets, limiting their ability to identify rare arrhythmia types. This study proposes a novel hybrid approach that integrates ConvNeXt-X deep learning models with advanced data balancing techniques to improve arrhythmia classification accuracy. Specifically, we evaluated three ConvNeXt variants—ConvNeXtTiny, ConvNeXtBase, and ConvNeXtSmall—combined with Random Oversampling (RO) and SMOTE-TomekLink (STL) on the MIT-BIH Arrhythmia Database. Experimental results demonstrate that the ConvNeXtTiny model paired with STL achieved the highest accuracy of 99.75%, followed by ConvNeXtTiny with RO at 99.72%. The STL technique consistently enhanced minority class detection and overall performance across models, with ConvNeXtBase and ConvNeXtSmall achieving accuracies of 99.69% and 99.72%, respectively. These findings highlight the efficacy of ConvNeXt-X models, when coupled with robust data balancing techniques, in achieving reliable and precise arrhythmia detection. This methodology holds significant potential for improving diagnostic accuracy and supporting clinical decision-making in healthcare.
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- 2024
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5. Electrocatalytic detection of Acetaminophen by sodium ferrite
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Saima Perveen, Jameel Ahmed Baig, Mohammad Nur-e-Alam, Mohsin Kazi, Shahabuddin Memon, Tasneem Gul Kazi, Khalil Akhtar, and Sajjad Hussain
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Electrochemical analysis, sodium ferrite nanoparticles ,Differential pulse voltammetry ,Glassy carbon electrode ,Acetaminophen ,Physics ,QC1-999 - Abstract
Acetaminophen (APN) is a safer alternative to opioids and is recognized for its analgesic and antipyretic properties. Prolonged usage and overdose of APN cause severe health problems for humans. Hence, its monitoring in the human body, pharmaceutical preparations and consumption sources is important. Thus, the current study was designed to synthesize the sodium ferrite nanoparticles (Na2Fe4O7-NPs) based on the Tamarindus indica fruit extract for selective trace electrochemical detection of APN. The Na2Fe4O7-NPs were characterized by advanced analytical techniques such as x-ray diffraction (XRD), fourier transform infrared (FTIR), UV–visible, atomic force microscopy (AFM), zeta potential, zeta sizer, energy dispersive x-ray (EDX) and field emission scanning electron microscopy (FESEM) which displayed that the Na2Fe4O7-NPs possess hexagonal structure, a narrow band gap (1.475 eV), corresponding to their excellent electronic capability, nanosize of particles, rough surface and highly stable nature for electrochemical analysis. Na2Fe4O7-NPs were deposited on a glassy carbon electrode (GCE) to manufacture an electrochemical sensor (Na2Fe4O7-NPs/GCE) and characterized its surface behaviour by cyclic voltammetry. Na2Fe4O7-NPs/GCE voltammetric sensor showed its selective sensing of APN in a wide dynamic range (1.0 × 10-8 to 4.5 × 10-4 M) with a detection limit of 2.72 10-9 M. Further, the developed method showed excellent stability in addition to reproducibility for the sensing of APN (% RSD < 5.0). The developed electrochemical sensor was found to be efficient for selective and sensitive detection of APN in real samples with quantitative recoveries (> 90 %).
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- 2025
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6. Anti-solvent materials enhanced structural and optical properties on ambiently fabricated perovskite thin films
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Mohammad Nur-E-Alam, Mohammad Aminul Islam, Yap Boon Kar, Tiong Sieh Kiong, Halina Misran, Mayeen Uddin Khandaker, Yasser Fouad, Manzoore Elahi M. Soudagar, and Erdem Cuce
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Perovskite ,Anti-solvent materials ,Degradation ,Crystallinity ,Bandgap ,PbI2 ,Medicine ,Science - Abstract
Abstract Perovskite solar cells (PSCs) hold potential for low-cost, high-efficiency solar energy, but their sensitivity to moisture limits practical application. Current fabrication requires controlled environments, limiting mass production. Researchers aim to develop stable PSCs with longer lifetimes under ambient conditions. In this research work, we investigated the stability of perovskite films and solar cells fabricated and annealed in natural air using four different anti-solvents: toluene, ethyl acetate, diethyl ether, and chlorobenzene. Films (about 300 nm thick) were deposited via single-step spin-coating and subjected to ambient air-atmosphere for up to 30 days. We monitored changes in crystallinity, electrical properties, and optics over time. Results showed a gradual degradation in the films’ crystallinity, morphology, and electro-optical properties. Notably, films made with ethyl acetate exhibited superior stability compared to other solvents. These findings contribute to advancing stable and high-performance PSCs manufactured under normal ambient conditions. In addition, we also discuss the possible machine learning (ML) approach to our future work direction to optimize the materials structures, and synthesis process parameters for future high-efficient perovskite solar cells fabrication.
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- 2024
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7. Evaluation of the Mechanical Properties of PLA Material Used For 3D Printing Solar E-Hub Component
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MD Helal Uddin, Mohammad Nur-E-Alam, Abreeza Manap, Boon Kar Yap, and Md Rokonuzzaman
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Additive manufacturing ,Sustainable materials ,Solar e-hub ,Mechanical testing ,Polylactic acid (PLA) ,Engineering machinery, tools, and implements ,TA213-215 ,Mechanics of engineering. Applied mechanics ,TA349-359 ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Chemical engineering ,TP155-156 ,Environmental engineering ,TA170-171 - Abstract
The advent of additive manufacturing (AM) technologies revolutionized design and production processes across various industries. In renewable energy, AM enabled new possibilities for optimizing solar e-hub (solar energy harvesting module) configurations, enhancing efficiency and performance. This study examined critical considerations such as material selection, durability, and cost-effectiveness in solar hub development. This fast-prototyping technique was controlled by computer-aided design (CAD) software like CREO Parametric 7.0 and Creality Slicer 4.8. Experimental results indicated that PLA (Polylactic acid) materials exhibited superior strength, with an impact energy of 4.8 Joules. The deformation study revealed that the maximum load of 22 MPa aligned with the ultimate tensile strength of PLA, and a hardness test result of 83.1 HRF featured its exemplary hardness properties. These findings advanced the understanding of using AM to investigate mechanical behaviours of PLA materials and optimize solar e-hub configurations for portable device applications, promoting sustainable energy solutions and the adoption of renewable energy technologies. In addition, the successful implementation of this approach will enable the renewable energy sectors to minimize the carbon foot-prints towards helping the global net-zero emissions by aligning the circular economy approach.
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- 2024
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8. Hyaluronic acid-solid lipid nano transporter serum preparation for enhancing topical tretinoin delivery: skin safety study and visual assessment of skin
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Yasir Mehmood, Hira Shahid, Syeda Momena Rizvi, Usama Jamshaid, Numera Arshad, Mohammad Nur-e-Alam, Muhammad Delwar Hussain, and Mohsin Kazi
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hyaluronic acid ,filler ,topical ,solvent ,diffusion ,tretinoin ,Therapeutics. Pharmacology ,RM1-950 - Abstract
The use of nanosized particles is becoming more popular for the topical treatment of skin conditions. In this research work, we created and investigated the effects of solid lipid nanoparticles (SLN) containing hyaluronic acid and tretinoin. Solvent emulsification diffusion method was used to prepare the SLN formulation and characterized for their physicochemical properties. Fourier transform infrared spectroscopy was used to confirm that hyaluronic acid and tretinoin were incorporated in the SLN. Furthermore, X-ray diffractogram, thermal analysis including DSC and TGA and in vitro dissolution, permeation tests were also performed along with microbial assessment. Clinical studies in human were performed to evaluate the effect of the SLN on skin wrinkles. The SLN was 750 ± 31.29 nm in size, with a zeta potential of 13.07 ± 0.75 mV and a narrow polydispersity index of 0.24 ± 0.12. The entrapment efficiency of tretinoin was found to be 90.07 ± 4.79%. Clinical studies in healthy human volunteers demonstrated that 90% of the tested individuals had improved skin conditions (reduction in wrinkles), by at least one grade after 4 weeks of treatment. Regarding the development on SLN, it was found that the internal phase concentration did not considerably affect the physicochemical and microbiological properties. Therefore, Hyaluronic acid has potential for the development of SLN applicable to cosmetic formulations, especially for skin. These findings show that the developed SLN have potential for use as cosmetics in the future.
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- 2024
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9. Predicting FFAR4 agonists using structure-based machine learning approach based on molecular fingerprints
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Zaid Anis Sherwani, Syeda Sumayya Tariq, Mamona Mushtaq, Ali Raza Siddiqui, Mohammad Nur-e-Alam, Aftab Ahmed, and Zaheer Ul-Haq
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FFAR4 ,Bayesian network algorithm ,Structure-based machine learning ,Molecular dynamics simulations ,Medicine ,Science - Abstract
Abstract Free Fatty Acid Receptor 4 (FFAR4), a G-protein-coupled receptor, is responsible for triggering intracellular signaling pathways that regulate various physiological processes. FFAR4 agonists are associated with enhancing insulin release and mitigating the atherogenic, obesogenic, pro-carcinogenic, and pro-diabetogenic effects, normally associated with the free fatty acids bound to FFAR4. In this research, molecular structure-based machine-learning techniques were employed to evaluate compounds as potential agonists for FFAR4. Molecular structures were encoded into bit arrays, serving as molecular fingerprints, which were subsequently analyzed using the Bayesian network algorithm to identify patterns for screening the data. The shortlisted hits obtained via machine learning protocols were further validated by Molecular Docking and via ADME and Toxicity predictions. The shortlisted compounds were then subjected to MD Simulations of the membrane-bound FFAR4-ligand complexes for 100 ns each. Molecular analyses, encompassing binding interactions, RMSD, RMSF, RoG, PCA, and FEL, were conducted to scrutinize the protein–ligand complexes at the inter-atomic level. The analyses revealed significant interactions of the shortlisted compounds with the crucial residues of FFAR4 previously documented. FFAR4 as part of the complexes demonstrated consistent RMSDs, ranging from 3.57 to 3.64, with minimal residue fluctuations 5.27 to 6.03 nm, suggesting stable complexes. The gyration values fluctuated between 22.8 to 23.5 nm, indicating structural compactness and orderliness across the studied systems. Additionally, distinct conformational motions were observed in each complex, with energy contours shifting to broader energy basins throughout the simulation, suggesting thermodynamically stable protein–ligand complexes. The two compounds CHEMBL2012662 and CHEMBL64616 are presented as potential FFAR4 agonists, based on these insights and in-depth analyses. Collectively, these findings advance our comprehension of FFAR4’s functions and mechanisms, highlighting these compounds as potential FFAR4 agonists worthy of further exploration as innovative treatments for metabolic and immune-related conditions.
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- 2024
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10. Cellulosic rich biomass production with optimized process parameters by using glycerol pretreatment for biofuels applications
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Muhammad Sulaiman, Hamayoun Mahmood, Haris Mahmood Khan, Tanveer Iqbal, Nehar Ullah Khan, Muhammad Mujtaba Abbas, Mohammad Nur-E-Alam, and Manzoore Elahi M. Soudagar
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Rice husk ,Pretreatment ,Glycerol ,Optimization ,RSM ,Renewable energy sources ,TJ807-830 ,Agriculture (General) ,S1-972 - Abstract
In this work, we conduct acidified aqueous glycerol pre-treatment (AAG) on rice husks (RH) and utilize the response surface methodology (RSM) to assess the impact of pre-treatment parameters. The primary objective of this research is to optimize the parameters to maximize the cellulose content within RH. The parameters under consideration encompassed temperature (ranging from 80 to 110 °C), retention time (spanning 15 to 45 min), and biomass loading (varying from 5 to 10 wt. %). To achieve this optimization, we perform the Box-Behnken Design (BBD) within the framework of RSM. Additionally, we scrutinize the interactive effects of these parameters on cellulose content. Our findings unveiled a remarkable increase in cellulose content, escalating from 40 % in untreated RH to an impressive 75 % in pre-treated RH under the optimized conditions of 110 °C for 45 min with a 5.0 wt. % biomass loading. To further evaluate the effectiveness of the pre-treatment process, we conduct scanning electron microscopy (SEM) and X-ray diffraction (XRD) analyses, shedding light on alterations in surface morphology and crystallinity of RH. This investigation yields valuable insights, presenting novel opportunities for the efficient conversion of readily available rice husks into high-value products, such as biofuels and composites.
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- 2024
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11. Mechanistic insight into the mode of inhibition of dietary flavonoids; targeting macrophage migration inhibitory factor
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Ali Raza Siddiqui, Mamona Mushtaq, Madiha Sardar, Lubna Atta, Mohammad Nur-e-Alam, Aftab Ahmad, and Zaheer Ul-Haq
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macrophage migration inhibitory factor ,dietary flavonoids ,molecular dynamic simulation ,principal component analysis ,ISO-1 ,Biology (General) ,QH301-705.5 - Abstract
Introduction: The Macrophage Migration Inhibitory Factor (MIF), a key pro-inflammatory mediator, is responsible for modulating immune responses. An array of inflammatory and autoimmune diseases has been linked to the dysregulated activity of MIF. The significance in physiological as well as pathophysiological phenomena underscores the potential of MIF as an attractive target with pharmacological relevance. Extensive research in past has uncovered a number of inhibitors, while the ISO-1, or (S, R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester being recognized as a benchmark standard so far. Recent work by Yang and coworkers identified five promising dietary flavonoids, with superior activity compared to the standard ISO-1. Nevertheless, the exact atomic-level inhibitory mechanism is still elusive.Methods: To improve the dynamic research, and rigorously characterize, and compare molecular signatures of MIF complexes with ISO-1 and flavonoids, principal component analysis (PCA) was linked with molecular dynamics (MD) simulations and binding free energy calculations.Results: The results suggest that by blocking the tautomerase site these small molecule inhibitors could modify the MIF activity by disrupting the intrinsic dynamics in particular functional areas. The stability matrices revealed the average deviation values ranging from 0.27–0.32 nm while the residue level fluctuations indicated that binding of the selected flavonoids confer enhanced stability relative to the ISO-1. Furthermore, the gyration values extracted from the simulated trajectories were found in the range of 1.80–1.83 nm.Discussion: Although all the tested flavonoids demonstrated remarkable results, the one obtained for the potent inhibitors, particularly Morin and Amentoflavone exhibited a good correlation with biological activity. The PCA results featured relatively less variance and constricted conformational landscape than others. The stable ensembles and reduced variation in turns might be the possible reasons for their outstanding performance documented previously. The results from the present exploration provide a comprehensive understanding of the molecular complexes formed by flavonoids and MIF, shedding light on their potential roles and impacts. Future studies on MIF inhibitors may benefit from the knowledge gathered from this investigation.
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- 2024
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12. Author Correction: Anti-solvent materials enhanced structural and optical properties on ambiently fabricated perovskite thin films
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Mohammad Nur-E-Alam, Mohammad Aminul Islam, Yap Boon Kar, Tiong Sieh Kiong, Halina Misran, Mayeen Uddin Khandaker, Yasser Fouad, Manzoore Elahi M. Soudagar, and Erdem Cuce
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Medicine ,Science - Published
- 2024
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13. Unravelling the Erythropoietin Heterodimeric Complex: In Silico Analysis of Complex Assembly and Binding Interface
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Atiya Habib, Urooj Qureshi, Mohammad Nur-e-Alam, Aftab Ahmed, and Zaheer Ul-Haq
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Chemistry ,QD1-999 - Abstract
Erythropoietin (Epo), a glycosylated protein categorized as a member of the cytokine family, is responsible for the modulation of erythrogenesis. Besides this, the nonhaematopoietic effects of Epo are associated with tissue-protective activity via an antiapoptotic pathway. This function of Epo is linked with its heterodimeric form, i.e. EpoR/βcR belonging to the cytokine family as well. Both receptors are dissected into three domains: extracellular (also known as ligand-binding domain), transmembrane and cytoplasmic domain. The transmembrane and cytoplasmic domains are assumed to play a paramount role in dimerization and tissue protection. However, the tertiary structure of cytoplasmic domains of both EpoR and βcR was not reported in the literature. Inspired by the potential therapeutic applications, we aimed to investigate the interaction pattern of EpoR/βcR using in silico tools. Cytoplasmic domains of EpoR and βcR were modelled, structural refinement was carried out through Rosetta, and these were then quality verified by well-known quality matrices. The observed results were found to be structurally consistent with the amenable geometry showing stereochemical sustainability. The modelled cytoplasmic domains were then successfully merged with the remaining domains (extracellular and transmembrane domains) of the respective receptors through MOEv2019.01 and Modeller. The complete structures of EpoR and βcR were subjected to geometry optimization and energy minimization via dynamic studies. The refined structures were subjected to protein–protein docking to yield the heterocomplex. Here, we report on the optimized structure coordinates of EpoR/βcR, the plausible electrostatic interactions involving G191, V206, T214, S241, T244, E336, R337, M342, G348, T349, E362 and K373 of EpoR and D336, S337, Y338, K333, R391, M426, H494, Q495, S717, S722, Y750 and G758 of βcR. Subsequently, we performed screening utilizing the StraPep database to identify Epo mimetic agents with the potential to enhance their tissue-protective effects. Following the virtual screening, four hits (4HQX, 4XO8, 1TPO and 3EZM) were obtained based on the binding affinity and protein–ligand interaction fingerprinting (PLIF). The stability exhibited by the four selected peptides in the binding site of the EpoR/βcR heterocomplex became visible during visual inspection. We propose that the presented model can be harnessed for future characterization studies.
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- 2024
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14. Design and Concept of Renewable Energy Driven Auto-Detectable Railway Level Crossing Systems in Bangladesh
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Iftekharuzzaman Iftekharuzzaman, Susmita Ghosh, Mohammad Khairul Basher, Mohammad Aminul Islam, Narottam Das, and Mohammad Nur-E-Alam
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railway crossing ,obstacle detection ,renewable energy ,hybrid system ,sustainable development ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Bangladesh’s railway system mostly uses typical manual railway crossing techniques or boom gates through its 2955.53 km rail route all over the country. Accidents frequently happen at railway crossings due to the lack of quickly operating gate systems, and to fewer safety measures at the railway crossing as well. Currently, there are very few automatic railway crossing systems available (without obstacle detectors). Additionally, all of them are dependent on the national power grid, without a backup plan for any emergency cases. Bangladesh is still running a bit behind in generating enough power for its consumption; hence, it is not possible to have a continuous power supply at all times all over the countryside. We aim to design and develop a smart railway crossing system with an obstacle detector to prevent common types of accidents at railway crossing points. We use two infrared (IR) sensors to operate the railway crossing systems, which are controlled by an Arduino Uno. This newly designed level crossing system is run with the help of sustainable renewable energy, which is cost-effective and eco-friendly, and applied under the national green energy policy towards achieving sustainable development in Bangladesh as a part of the global sustainable goal to face climate change challenges. We have summarized the simulated the results of several renewable energy sources, including a hybrid system, and optimized the Levelized Cost of Energy (LCOE) and the payback periods.
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- 2023
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15. Rooftop PV or Hybrid Systems and Retrofitted Low-E Coated Windows for Energywise and Self-Sustainable School Buildings in Bangladesh
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Mohammad Nur-E-Alam, Mohammad Khairul Basher, Iftekharuzzaman, Kazi Zehad Mostofa, Mohammad Aminul Islam, A. H. M. Ahashanul Haque, and Narottam Das
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HOMER pro software ,low-E coatings ,rooftop PV ,retrofitted glass ,school building ,thin film ,Production of electric energy or power. Powerplants. Central stations ,TK1001-1841 - Abstract
The electricity crisis is a common issue in Bangladesh; however, recently the electricity scenario has been getting worse due to various reasons including power generation and distribution all over the country. Meanwhile, the large number of people requires a huge amount of energy which is not possible to be met by the national grid due to the limited power generation from different plants. Among all renewable energy sources, the solar photovoltaics (PV) system is the best choice as a generation source, either off-grid or with a grid-tied connection, to reduce the pressure on the national grid. In Bangladesh, there are more than 175,000 schools, and it is possible to generate a huge amount of renewable (solar) power to supply all the schools by using rooftop PV systems. We propose a new approach that combines solar energy harvesting and savings to make the schools self-sufficient and energywise. We performed a Hybrid Optimization Model for Multiple Energy Resources (HOMER) pro simulation and find that it was possible to generate approximately 200 megawatts (MW) of power. We conducted a feasibility study on generating power from rooftop PV systems on school buildings and reduced the power consumption using retrofitted thin-film-coated glass by around 16–20% per day depending on the school size, which can help the national power grid system by either making all the schools off-grid or grid-connected to supply power to the national grid. In addition, we perform a HelioScope simulation to investigate the maximum upscaling of PV sizing for the rooftops of school buildings in Bangladesh to realize how to make each school a mini solar power station in the future. The HelioScope simulation performance showed that it was possible to generate approximately 96,993 kWh per year from one school building.
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- 2022
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16. Physical-Vapor-Deposited Metal Oxide Thin Films for pH Sensing Applications: Last Decade of Research Progress
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Mohammad Nur-E-Alam, Devendra Kumar Maurya, Boon Kar Yap, Armin Rajabi, Camellia Doroody, Hassan Bin Mohamed, Mayeen Uddin Khandaker, Mohammad Aminul Islam, and Sieh Kiong Tiong
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thin film ,metal oxide ,pH sensor ,sensitivity ,Chemical technology ,TP1-1185 - Abstract
In the last several decades, metal oxide thin films have attracted significant attention for the development of various existing and emerging technological applications, including pH sensors. The mandate for consistent and precise pH sensing techniques has been increasing across various fields, including environmental monitoring, biotechnology, food and agricultural industries, and medical diagnostics. Metal oxide thin films grown using physical vapor deposition (PVD) with precise control over film thickness, composition, and morphology are beneficial for pH sensing applications such as enhancing pH sensitivity and stability, quicker response, repeatability, and compatibility with miniaturization. Various PVD techniques, including sputtering, evaporation, and ion beam deposition, used to fabricate thin films for tailoring materials’ properties for the advanced design and development of high-performing pH sensors, have been explored worldwide by many research groups. In addition, various thin film materials have also been investigated, including metal oxides, nitrides, and nanostructured films, to make very robust pH sensing electrodes with higher pH sensing performance. The development of novel materials and structures has enabled higher sensitivity, improved selectivity, and enhanced durability in harsh pH environments. The last decade has witnessed significant advancements in PVD thin films for pH sensing applications. The combination of precise film deposition techniques, novel materials, and surface functionalization strategies has led to improved pH sensing performance, making PVD thin films a promising choice for future pH sensing technologies.
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- 2023
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17. A neoclerodane orthoester and other new neoclerodane diterpenoids from Teucrium yemense chemistry and effect on secretion of insulin
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Mohammad Nur-e-Alam, Ifat Parveen, Barrie Wilkinson, Sarfaraz Ahmed, Rahman M. Hafizur, Ahmed Bari, Timothy J. Woodman, Michael D. Threadgill, and Adnan J. Al-Rehaily
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Medicine ,Science - Abstract
Abstract Teucrium yemense, a medicinal plant commonly grown in Saudi Arabia and Yemen, is traditionally used to treat infections, kidney diseases, rheumatism, and diabetes. Extraction of the dried aerial parts of the plant with methanol, followed by further extraction with butanol and chromatography, gave twenty novel neoclerodanes. Their structures, relative configurations and some conformations were determined by MS and 1-D and 2-D NMR techniques. Most were fairly conventional but one contained an unusual stable orthoester, one had its (C-16)–(C-13)–(C-14)–(C-15) (tetrahydro)furan unit present as a succinic anhydride and one had a rearranged carbon skeleton resulting from ring-contraction to give a central octahydroindene bicyclic core, rather than the usual decalin. Mechanisms are proposed for the biosynthetic formation of the orthoester and for the ring-contraction. Four novel neoclerodanes increased the glucose-triggered release of insulin from isolated murine pancreatic islets by more than the standard drug tolbutamide, showing that they are potential leads for the development of new anti-diabetic drugs.
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- 2021
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18. A comprehensive study on antibacterial antioxidant and photocatalytic activity of achyranthes aspera mediated biosynthesized Fe2O3 nanoparticles
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Waseem Ahmad, Vishal Singh, Sarfaraz Ahmed, and Mohammad Nur-e-Alam
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Fe2O3 NPs ,Antibacterial activity ,Photocatalytic activity ,Antioxidant activity ,Achyranthes aspera ,Technology - Abstract
During the last few decades the field of nanotechnology has witnessed tremendous amounts of research on inorganic metal oxide nanoparticles. The magnetic iron oxide nanoparticles have attracted lots of attention due to its unique properties and very wide field of applications. In this regard, present investigation represents a non toxic eco-friendly low cost method for the fabrication of iron oxide nanoparticles. The structural and morphological analyses of fabricated nanoparticles were performed by using some standard analytical procedures like X-Ray diffraction, Scanning electron microscope, UV visible spectroscopy and IR spectroscopy. The X-ray diffraction analysis revealed that the fabricated nanoparticles are crystalline in nature and have 20 nm average particle sizes. The Proposed manuscript highlights the antibacterial antioxidant and photocatalytic activity of the fabricated nanoparticles. The fabricated nanoparticles show significant antibacterial, antioxidant and photocatalytic activity.
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- 2022
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19. Aesthetically Appealing Building Integrated Photovoltaic Systems for Net-Zero Energy Buildings. Current Status, Challenges, and Future Developments—A Review
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Mohammad Khairul Basher, Mohammad Nur-E-Alam, Md Momtazur Rahman, Kamal Alameh, and Steven Hinckley
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semitransparent PV ,colored PV ,BIPV ,net-zero energy building ,sustainable environment ,Building construction ,TH1-9745 - Abstract
With the sharp increase in global energy demand, industrial and residential buildings are responsible for around 40% of the energy consumed with most of this energy portion being generated by non-renewable sources, which significantly contribute to global warming and environmental hazards. The net-zero energy building (NZEB) concept attempts to solve the global warming issue, whereby a building will produce, on-site, its required energy demand throughout the year from renewable energy sources. This can be achieved by integrating photovoltaic (PV) building materials, called building-integrated photovoltaic (BIPV) modules, throughout the building skin, which simultaneously act as construction materials and energy generators. Currently, architects and builders are inclined to design a building using BIPV modules due to the limited colors available, namely, black or blue, which result in a monotonous building appearance. Therefore, there is an increasing demand/need to develop modern, aesthetically pleasing BIPV green energy products for the use of architects and the construction industry. This review article presents the current stage and future goal of advanced building integrated photovoltaic systems, focusing on the aesthetically appealing BIPV systems, and their applications towards overcoming global challenges and stepping forward to achieve a sustainable green energy building environment. Additionally, we present the summary and outlook for the future development of aesthetically appealing building integrated photovoltaic systems.
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- 2023
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20. Compounds Related to Saudin and Three New Series of Diterpenoids from Clutia lanceolata
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Sarfaraz Ahmed, Mohammad Nur-e-Alam, Ifat Parveen, Michael D. Threadgill, James B. Orton, Rahman M. Hafizur, Israr Khan, Mai Al-Oqail, and Adnan J. Al-Rehaily
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Pharmacology ,Complementary and alternative medicine ,Organic Chemistry ,Drug Discovery ,Pharmaceutical Science ,Molecular Medicine ,Analytical Chemistry - Published
- 2023
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21. Insilico structure based drug design approach to find potential hits in ventilator-associated pneumonia caused by Pseudomonas aeruginosa.
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Manoj G. Damale, Rajesh B. Patil, Siddique Akber Ansari, Hamad M. Alkahtani, Sarfaraz Ahmed, Mohammad Nur-e-Alam, Rohidas Arote, and Jaiprakash N. Sangshetti
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- 2022
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22. Structure-Based Discovery of Potent Staphylococcus aureus Thymidylate Kinase Inhibitors by Virtual Screening
- Author
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Zaheer Ul-Haq, Bakhtawer Qureshi, Ruqaiya Khalil, Maria Saeed, Mohammad Nur-e-Alam, and Sarfaraz Ahmed
- Subjects
Drug Discovery - Abstract
Introduction: Multidrug-resistant bacteria are rapidly increasing worldwide, increasing antibiotic resistance. The exploitation, misuse, overuse, and decrease of the therapeutic potential of currently available antibiotics have resulted in the development of resistance against bacteria. As the most common bacterial pathogen in humans, Staphylococcus aureus can cause many adverse health effects. In fighting multidrug-resistant Staphylococcus aureus, scientists have identified an extremely relevant target - SaTMPK. SaTMPK is essential for DNA synthesis, which, in turn, is necessary for the replication and cell division of bacteria. Objective: To perform multi-stage screening using the ZINC database, followed by molecular docking, ADMET profiling, molecular dynamics simulations, and energy calculations. Methods: Based on the similar pharmacophoric characteristics of existing SaTMPK crystal structures, a model of interaction-based pharmacophores was developed. We then performed molecular docking studies on the positive hits obtained from the pharmacophore screening. Compounds that exhibited good molecular interactions within the SaTMPK binding sites were further evaluated using in-silico ADMET profiling. Results: In a multi-stage screening campaign, three compounds were shortlisted that exhibited physicochemical characteristics suitable for human administration. Conclusion: The findings from this study should contribute to in vitro and in vivo studies for clinical applications.
- Published
- 2023
- Full Text
- View/download PDF
23. Virtual Screening, Synthesis and Biological Evaluation of Streptococcus mutans Mediated Biofilm Inhibitors
- Author
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Lubna Atta, Ruqaiya Khalil, Khalid Mohammed Khan, Moatter Zehra, Faiza Saleem, Mohammad Nur-e-Alam, and Zaheer Ul-Haq
- Subjects
dental caries ,biofilm ,glucosyltransferases ,virtual screening ,antibiofilm ,antimicrobial ADMET profiling ,Organic chemistry ,QD241-441 - Abstract
Dental caries, a global oral health concern, is a biofilm-mediated disease. Streptococcus mutans, the most prevalent oral microbiota, produces extracellular enzymes, including glycosyltransferases responsible for sucrose polymerization. In bacterial communities, the biofilm matrix confers resistance to host immune responses and antibiotics. Thus, in cases of chronic dental caries, inhibiting bacterial biofilm assembly should prevent demineralization of tooth enamel, thereby preventing tooth decay. A high throughput screening was performed in the present study to identify small molecule inhibitors of S. mutans glycosyltransferases. Multiple pharmacophore models were developed, validated with multiple datasets, and used for virtual screening against large chemical databases. Over 3000 drug-like hits were obtained that were analyzed to explore their binding mode. Finally, six compounds that showed good binding affinities were further analyzed for ADME (absorption, distribution, metabolism, and excretion) properties. The obtained in silico hits were evaluated for in vitro biofilm formation. The compounds displayed excellent antibiofilm activities with minimum inhibitory concentration (MIC) values of 15.26–250 µg/mL.
- Published
- 2022
- Full Text
- View/download PDF
24. Formation of few-layer graphene flake structures from graphite particles during thin film coating using dry spray deposition method
- Author
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Nasim, Mohammad Nur E Alam Al and Chun, Doo-Man
- Published
- 2017
- Full Text
- View/download PDF
25. Substrate-dependent deposition behavior of graphite particles dry-sprayed at room temperature using a nano-particle deposition system
- Author
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Nasim, Mohammad Nur E Alam Al and Chun, Doo-Man
- Published
- 2017
- Full Text
- View/download PDF
26. Combination of nano-particle deposition system and friction stir spot welding for fabrication of carbon/aluminum metal matrix composite joints of dissimilar aluminum alloys
- Author
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Hong, Sung-Tae, Das, Hrishikesh, Oh, Hyun-Seok, Nasim, Mohammad Nur E Alam Al, and Chun, Doo-Man
- Published
- 2017
- Full Text
- View/download PDF
27. Nano-grating Assisted Light Absorption Enhancement for MSM-PDs Performance Improvement: An Updated Review
- Author
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Narottam Das, Mohammad Nur-E-Alam, Alif Islam, and Ain Zulaikha Maslihan Ain
- Subjects
nano-grating ,metal-semiconductor-metal photodetector ,light absorption enhancement ,absorption coefficient ,opto-electronic devices ,Applied optics. Photonics ,TA1501-1820 - Abstract
The primary focus of this review article mainly emphasizes the light absorption enhancement for various nanostructured gratings assisted metal-semiconductor-metal photodetectors (MSM-PDs) that are so far proposed and developed for the improvement of light capturing performance. The MSM-PDs are considered as one of the key elements in the optical and high-speed communication systems for applications such as faster optical fiber communication systems, sensor networks, high-speed chip-to-chip interconnects, and high-speed sampling. The light absorption enhancement makes the MSM-PDs an ideal candidate due to their excellent performances in detection, especially in satisfying the high-speed or high-performance device requirements. The nano-grating assisted MSM-PDs are preordained to be decorous for many emerging and existing communication device applications. There have been a significant number of research works conducted on the implementation of nano-gratings, and still, more researches are ongoing to raise the performance of MSM-PDs particularly, in terms of enhancing the light absorption potentialities. This review article aims to provide the latest update on the exertion of nano-grating structures suitable for further developments in the light absorption enhancement of the MSM-PDs.
- Published
- 2021
- Full Text
- View/download PDF
28. Deposition behavior and tribological properties of diamond-like carbon coatings on stainless steels via chemical vapor deposition
- Author
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Mustafi, Labani, Rahman, M. M., Al Nasim, Mohammad Nur E. Alam, Chowdhury, Mohammad Asaduzzaman, and Monir, M. H.
- Published
- 2018
- Full Text
- View/download PDF
29. Diversity oriented biosynthesis via accelerated evolution of modular gene clusters
- Author
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Aleksandra Wlodek, Steve G. Kendrew, Nigel J. Coates, Adam Hold, Joanna Pogwizd, Steven Rudder, Lesley S. Sheehan, Sarah J. Higginbotham, Anna E. Stanley-Smith, Tony Warneck, Mohammad Nur-E-Alam, Markus Radzom, Christine J. Martin, Lois Overvoorde, Markiyan Samborskyy, Silke Alt, Daniel Heine, Guy T. Carter, Edmund I. Graziani, Frank E. Koehn, Leonard McDonald, Alexander Alanine, Rosa María Rodríguez Sarmiento, Suzan Keen Chao, Hasane Ratni, Lucinda Steward, Isobel H. Norville, Mitali Sarkar-Tyson, Steven J. Moss, Peter F. Leadlay, Barrie Wilkinson, and Matthew A. Gregory
- Subjects
Science - Abstract
Reengineering polyketide synthase encoding genes to produce analogues of natural products can be slow and low-yielding. Here the authors use accelerated evolution to recombine the gene cluster for rapid production of rapamycin-related products.
- Published
- 2017
- Full Text
- View/download PDF
30. Physical Vapor-Deposited Silver (Ag)-Based Metal-Dielectric Nanocomposites for Thin-Film and Coating Applications
- Author
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Mohammad Nur-E-Alam, Mohammad Khairul Basher, Mikhail Vasiliev, and Narottam Das
- Subjects
nanocomposite ,thin-film materials ,coatings ,spectrally selective coating ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
Metallic thin-film materials and nanoparticles (mainly silver (Ag)-based) are recently being used in many nano-technological applications, including sensors, reflective heat-mirror coatings, and antibacterial coatings. The physical vapor deposition technique has attracted significant attention for Ag-based nanocomposites with tailoring of the structural and optical properties of metallic thin films, thus allowing for further improvements and application possibilities in various existing fields, namely electronics, catalysis, magnetics, and optics, alongside the environment and health and new emergent fields, particularly thin-film coatings. This study highlights the preparation, characterization, properties, and possible future application directions of several types of silver (Ag)-based nanocomposite thin films prepared by using physical vapor deposition techniques. The high-temperature (above 300 °C) heat-treated composite layer shows significant spectral shifts; however, distinguishingly notable sizes of nanoparticles are not observed, which indicates that this newly developed composite material can be useful for various coating applications.
- Published
- 2021
- Full Text
- View/download PDF
31. Design, Development, and Characterization of Low Distortion Advanced Semitransparent Photovoltaic Glass for Buildings Applications
- Author
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Mohammad Khairul Basher, Mohammad Nur-E Alam, and Kamal Alameh
- Subjects
semitransparent PV ,BIPV ,NZEB ,renewable energy ,sustainable energy ,environmental safety ,Technology - Abstract
Aesthetic appearance of building-integrated photovoltaic (BIPV) products, such as semitransparent PV (STPV) glass, is crucial for their widespread adoption and contribution to the net-zero energy building (NZEB) goal. However, the visual distortion significantly limits the aesthetics of STPV glass. In this study, we investigate the distortion effect of transparent periodic-micropattern-based thin-film PV (PMPV) panels available in the market. To minimize the visual distortion of such PMPV glass panel types, we design and develop an aperiodic micropattern-based PV (APMP) glass that significantly reduces visual distortion. The developed APMP glass demonstrates a haze ratio of 3.7% compared to the 10.7% of PMPV glass. Furthermore, the developed AMPV glass shows an average visible transmittance (AVT) of 58.3% which is around 1.3 times higher than that of AMPV glass (43.8%). Finally, the measured CIELAB values (L* = 43.2, a* = −1.55, b* = −2.86.) indicate that our developed AMPV glass possesses excellent color neutrality, which makes them suitable for commercial applications. Based on the characterization results, this study will have a significant impact on the areas of smart window glasses that can play a vital role in developing a sustainable environment and enhancing the aesthetical appearance of net-zero energy buildings (NZEB).
- Published
- 2021
- Full Text
- View/download PDF
32. Sensing of Surface and Bulk Refractive Index Using Magnetophotonic Crystal with Hybrid Magneto-Optical Response.
- Author
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Daria Ignatyeva, Pavel Kapralov, Polina Golovko, Polina Shilina, Anastasiya E. Khramova, Sergey K. Sekatskii, Mohammad Nur-E-Alam, Kamal E. Alameh, Mikhail O. Vasiliev, Andrey Kalish, and Vladimir Belotelov
- Published
- 2021
- Full Text
- View/download PDF
33. Titanium Nitride Thin Film Based Low-Redox-Interference Potentiometric pH Sensing Electrodes.
- Author
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Shimrith Paul Shylendra, Wade Lonsdale, Magdalena Wajrak, Mohammad Nur-E-Alam, and Kamal E. Alameh
- Published
- 2021
- Full Text
- View/download PDF
34. The anti-oxidative, anti-cell proliferative and anti-microbial efficacies of cold-adapted Crepis flexuosa: HPTLC and GC/MS analyses
- Author
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Mohammad K. Parvez, Mohammed S. Al-Dosari, Sarfaraz Ahmed, Omar M. Noman, Adnan J. Al-Rehaily, and Mohammad Nur-e-Alam
- Subjects
General Agricultural and Biological Sciences - Published
- 2022
- Full Text
- View/download PDF
35. Sambucus Canadensis leaf extract mediated synthesis and analysis of antibacterial and photocatalytic degradation property of stannous oxide nanoparticles
- Author
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Waseem Ahmad, Agrima Pandey, Sarfaraz Ahmed, and Mohammad Nur-e-Alam
- Subjects
Environmental Engineering ,Environmental Chemistry ,Bioengineering - Published
- 2023
- Full Text
- View/download PDF
36. Light Reflection Loss Reduction by Nano-Structured Gratings for Highly Efficient Next-Generation GaAs Solar Cells
- Author
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Narottam Das, Devanandh Chandrasekar, Mohammad Nur-E-Alam, and M. Masud K. Khan
- Subjects
aspect ratio ,conversion efficiency ,FDTD simulation ,GaAs substrate ,light absorption ,nano-grating structures ,Technology - Abstract
This paper mainly focuses on increasing the conversion efficiency of GaAs solar cells by reducing the light reflection losses. The design of nano-structured gratings and their light trapping performance are modelled and optimised by using the finite-difference time-domain (FDTD) method. The sunlight directly impinges on the solar panel or cells, then a portion of the incident sunlight reflects back to the air from the surface of the panel, thus leading to a reduction in the light absorption capacity of the solar cells. In order to proliferate the light absorption capacity of solar cells nano-grating structures are employed, as they are highly capable of capturing the incident sunlight compared to a conventional (or flat type) solar cell, which results in generating more electrical energy. In this study, we design three different types of nano-grating structures, optimise their parameters and their performance in light capturing capacity. From the simulation results, we confirm that that it is possible to reduce light reflection losses up to 27%, by using the nano-grating structures, compared to conventional type solar cells. This reduction of reflection losses helps to improve the conversion efficiency of next-generation GaAs solar cells significantly for a sustainable green Earth.
- Published
- 2020
- Full Text
- View/download PDF
37. Development of zinc-oxide nanorods on chemically etched zinc plates suitable for high-efficiency photovoltaics solar cells
- Author
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Mohammad Khairul Basher, S. M. Shah Riyadh, M. Khalid Hossain, Mahmudul Hassan, Md. Abdur Rafiq Akand, S. M. Amir-Al Zumahi, Md. Abdul Matin, Narottam Das, and Mohammad Nur-E-Alam
- Subjects
Electrical and Electronic Engineering ,Atomic and Molecular Physics, and Optics ,Electronic, Optical and Magnetic Materials - Published
- 2023
- Full Text
- View/download PDF
38. Understanding the Degradation Factors, Mechanism and Initiatives for Highly Efficient Perovskite Solar Cells
- Author
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Md. Helal Miah, Md. Bulu Rahman, Mohammad Nur‐E‐Alam, Narottam Das, Norhayati Binti Soin, Sharifah Fatmadiana Wan Muhammad Hatta, and Mohammad Aminul Islam
- Subjects
Biomaterials ,Renewable Energy, Sustainability and the Environment ,Materials Chemistry ,Energy Engineering and Power Technology - Published
- 2023
- Full Text
- View/download PDF
39. Structural basis for the mutation-induced dysfunction of the human IL-15/IL-15α receptor complex
- Author
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Zahida Batool, Urooj Qureshi, Mamona Mushtaq, Sarfaraz Ahmed, Mohammad Nur-e-Alam, and Zaheer Ul-Haq
- Subjects
General Physics and Astronomy ,Physical and Theoretical Chemistry - Abstract
In silico strategies offer a reliable, fast, and inexpensive, way compared to the clumsy in vitro approaches to boost understanding of the effect of amino acid substitution on the structure and consequently the associated function of proteins.
- Published
- 2023
40. Bi-substituted Ferrite Garnet Type Magneto-Optic Materials Studied at ESRI Nano-Fabrication Laboratories, ECU, Australia
- Author
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Mohammad Nur-E-Alam, Mikhail Vasiliev, and Kamal Alameh
- Subjects
surfaces,_coatings_films ,Materials Chemistry ,Surfaces and Interfaces ,Surfaces, Coatings and Films - Abstract
Since 2007, at the Electron Science Research Institute (ESRI) nano-fabrication laboratories, Edith Cowan University, Australia, we have devoted research efforts to the synthesis and characterization of bismuth-containing ferrite-garnet-type thin-film magneto-optic (MO) materials of different compositions. We report on the growth and characteristics of radio frequency (RF) magnetron sputtered bismuth-substituted iron-garnet thin films. We study the process parameters associated with the RF magnetron sputter deposition technique and investigate the results of optimizing process parameters. To achieve the best MO properties, we employ a few unique techniques, such as co-sputtered nanocomposite films and all-garnet multilayer structures, as well as the application of oxygen plasma treatment to amorphous garnet layers immediately following the deposition process. We demonstrated a remarkable enhancement in the MO properties of Bi-containing ferrite-type garnet thin-film materials, including record-high MO figures of merit and improved conventional and unconventional hysteresis loops of Faraday rotation. Previously unpublished research results on the forward-looking applications of magnetic garnet coatings applied to microparticles of advanced luminescent materials are reported. In the context of developing the next-generation ultra-fast optoelectronic devices, such as light intensity switches and modulators, high-speed flat panel displays, and high-sensitivity sensors, it is important to consider the desirable optical, magnetic, and magneto-optic properties that are found in highly bismuth-substituted iron garnet thin-film materials of various composition types.
- Published
- 2022
- Full Text
- View/download PDF
41. Simulation and Optimization of Nano-structured Gratings Alternative of Thin-film Anti-Reflectors for GaAs Solar Cells Conversion Efficiency Improvement
- Author
-
Narottam Das, Ashish Sharma, Mohammad Khairul Basher, and Mohammad Nur-E-Alam
- Published
- 2022
- Full Text
- View/download PDF
42. Initial Field Testing Results from Building-Integrated Solar Energy Harvesting Windows Installation in Perth, Australia
- Author
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Mikhail Vasiliev, Mohammad Nur-E-Alam, and Kamal Alameh
- Subjects
renewables ,energy saving and generation ,built environments ,solar windows ,advanced glazings ,photovoltaics ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
We report on the field testing datasets and performance evaluation results obtained from a commercial property-based visually-clear solar window installation site in Perth-Australia. This installation was fitted into a refurbished shopping center entrance porch and showcases the potential of glass curtain wall-based solar energy harvesting in built environments. In particular, we focus on photovoltaic (PV) performance characteristics such as the electric power output, specific yield, day-to-day consistency of peak output power, and the amounts of energy generated and stored daily. The dependencies of the generated electric power and stored energy on multiple environmental and geometric parameters are also studied. An overview of the current and future application potential of high-transparency, visually-clear solar window-based curtain wall installations suitable for practical building integration is provided.
- Published
- 2019
- Full Text
- View/download PDF
43. Analysis, Optimization, and Characterization of Magnetic Photonic Crystal Structures and Thin-Film Material Layers
- Author
-
Mikhail Vasiliev, Kamal Alameh, and Mohammad Nur-E-Alam
- Subjects
1D magnetic photonic crystals ,multilayer film modeling ,modeling of Faraday rotation spectra ,MPC optimization ,exhaustive computation ,materials characterization ,Technology - Abstract
The development of magnetic photonic crystals (MPC) has been a rapidly evolving research area since the late 1990s. Magneto-optic (MO) materials and the techniques for their characterization have also continually undergone functional and property-related improvements. MPC optimization is a feature-rich Windows software application designed to enable researchers to analyze the optical and magneto-optical spectral properties of multilayers containing gyrotropic constituents. We report on a set of computational algorithms which aim to optimize the design and the optical or magneto-optical spectral analysis of 1D MPC, together with a Windows software implementation. Relevant material property datasets (e.g., the spectral dispersion data for the refractive index, absorption, and gyration) of several important optical and MO materials are included, enabling easy reproduction of the previously published results from the field of MPC-based Faraday rotator development, and an effective demonstration-quality introduction of future users to the multiple features of this package. We also report on the methods and algorithms used to obtain the absorption coefficient spectral dispersion datasets for new materials, where the film thickness, transmission spectrum, and refractive index dispersion function are known.
- Published
- 2019
- Full Text
- View/download PDF
44. Recent Developments in Solar Energy-Harvesting Technologies for Building Integration and Distributed Energy Generation
- Author
-
Mikhail Vasiliev, Mohammad Nur-E-Alam, and Kamal Alameh
- Subjects
renewables ,energy saving and generation ,built environments ,transparent concentrators ,luminescent concentrators ,solar windows ,advanced glazings ,photovoltaics ,Technology - Abstract
We present a review of the current state of the field for a rapidly evolving group of technologies related to solar energy harvesting in built environments. In particular, we focus on recent achievements in enabling the widespread distributed generation of electric energy assisted by energy capture in semi-transparent or even optically clear glazing systems and building wall areas. Whilst concentrating on recent cutting-edge results achieved in the integration of traditional photovoltaic device types into novel concentrator-type windows and glazings, we compare the main performance characteristics reported with these using more conventional (opaque or semi-transparent) solar cell technologies. A critical overview of the current status and future application potential of multiple existing and emergent energy harvesting technologies for building integration is provided.
- Published
- 2019
- Full Text
- View/download PDF
45. Mechanistic insights into the inhibitory activity of FDA approved ivermectin against SARS-CoV-2: old drug with new implications
- Author
-
Urooj Qureshi, Sarfaraz Ahmed, Sehrish Naz, Zaheer Ul-Haq, Mohammad Nur-e-Alam, and Sonia Mir
- Subjects
IVM/IMP-α1 complexes ,Drug ,binding-free energy calculation ,media_common.quotation_subject ,Nuclear Localization Signals ,030303 biophysics ,Molecular Dynamics Simulation ,Pharmacology ,Biology ,Approved drug ,Viral Proteins ,03 medical and health sciences ,Structural Biology ,Humans ,NLS ,Binding site ,Molecular Biology ,media_common ,0303 health sciences ,Ivermectin ,SARS-CoV-2 ,urogenital system ,MD simulation ,General Medicine ,COVID-19 Drug Treatment ,Molecular Docking Simulation ,Docking (molecular) ,embryonic structures ,Nuclear transport ,Viral load ,Nuclear localization sequence ,Research Article - Abstract
The novel corona virus (Covid-19) has become a great challenge worldwide since 2019, as no drug has been reported yet. Different clinical trials are still under way. Among them is Ivermectin (IVM), an FDA approved drug which was recently reported as a successful candidate to reduce SARS-CoV-2 viral load by inhibiting Importin-α1 (IMP-α1) protein which subsequently affects nuclear transport of viral proteins but its basic binding mode and inhibitory mechanism is unknown. Therefore, we aimed to explore the inhibitory mechanism and binding mode of IVM with IMP-α1 via different computational methods. Initially, comparative docking of IVM was performed against two different binding sites (Nuclear Localization Signal (NLS) major and minor sites) of IMP-α1 to predict the probable binding mode of IVM. Then, classical MD simulation was performed (IVM/NLS-Major site and IVM/NLS-Minor site), to predict its comparative stability dynamics and probable inhibitory mechanism. The stability dynamics and biophysical analysis of both sites highlighted the stable binding of IVM within NLS-Minor site by establishing and maintaining more hydrophobic contacts with crucial residues, required for IMP-α1 inhibition which were not observed in NLS-major site. Altogether, these results recommended the worth of IVM as a possible drug to limit the SARS-CoV-2 viral load and consequently reduces its progression. Communicated by Ramaswamy H. Sarma
- Published
- 2021
- Full Text
- View/download PDF
46. Nanophotonic structures with optical surface modes for tunable spin current generation
- Author
-
Daria O. Ignatyeva, A. K. Zvezdin, Sergey K. Sekatskii, P. V. Shilina, Kamal Alameh, Seyedeh Mehri Hamidi, Yongchao Song, Venu Gopal Achanta, P. O. Kapralov, Vladimir I. Belotelov, Mikhail Vasiliev, and Mohammad Nur-E-Alam
- Subjects
Coupling ,Materials science ,Nanostructure ,Spintronics ,business.industry ,Nanophotonics ,Physics::Optics ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Ray ,Wavelength ,Ferromagnetism ,0103 physical sciences ,Optoelectronics ,General Materials Science ,010306 general physics ,0210 nano-technology ,business ,Spin-½ - Abstract
We propose a novel type of photonic-crystal (PC)-based nanostructures for efficient and tunable optically-induced spin current generation via the spin Seebeck and inverse spin Hall effects. It has been experimentally demonstrated that optical surface modes localized at the PC surface covered by ferromagnetic layer and materials with giant spin-orbit coupling (SOC) notably increase the efficiency of the optically-induced spin current generation, and provides its tunability by modifying the light wavelength or angle of incidence. Up to 100% of the incident light power can be transferred to heat within the SOC layer and, therefore, to the spin current. Importantly, the high efficiency becomes accessible even for ultra-thin SOC layers. Moreover, the surface patterning of the PC-based spintronic nanostructure allows for the local generation of spin currents at the pattern scales rather than the diameter of the laser beam.
- Published
- 2021
- Full Text
- View/download PDF
47. Semi-Transparent Energy-Harvesting Solar Concentrator Windows Employing Infrared Transmission-Enhanced Glass and Large-Area Microstructured Diffractive Elements
- Author
-
Mikhail Vasiliev, Kamal Alameh, Mohsin Ali Badshah, Seok-Min Kim, and Mohammad Nur-E-Alam
- Subjects
solar windows ,advanced glazings ,diffractive elements ,light trapping ,photovoltaics ,Applied optics. Photonics ,TA1501-1820 - Abstract
We report on the study of energy-harvesting performance in medium-size (400 cm2) glass-based semitransparent solar concentrators employing edge-mounted photovoltaic modules. Systems using several different types of glazing system architecture and containing embedded diffractive structures are prepared and characterized. The technological approaches to the rapid manufacture of large-area diffractive elements suitable for use in solar window-type concentrators are described. These elements enable the internal deflection and partial trapping of light inside glass-based concentrator windows. We focus on uncovering the potential of pattern-transfer polymer-based soft lithography for enabling both the improved photon collection probability at solar cell surfaces, and the up-scaling of semitransparent solar window dimensions. Results of photovoltaic characterization of several solar concentrators employing different internal glazing-system structure and diffractive elements produced using different technologies are reported and discussed.
- Published
- 2018
- Full Text
- View/download PDF
48. Spectrally-Selective Energy-Harvesting Solar Windows for Public Infrastructure Applications
- Author
-
Mikhail Vasiliev, Kamal Alameh, and Mohammad Nur-E-Alam
- Subjects
solar windows ,advanced glazing ,low-emissivity spectrally-selective coatings ,photovoltaics ,Technology ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Biology (General) ,QH301-705.5 ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
A study of photovoltaic solar window technologies is reported and it focuses on their structural features, functional materials, system development, and suitability for use in practical field applications including public infrastructures and agricultural installations. Energy generation performance characteristics are summarized and compared to theory-limit predictions. Working examples of pilot-trial solar window-based installations are described. We also report on achieving electric power outputs of about 25 Wp/m2 from clear and transparent large-area glass-based solar windows.
- Published
- 2018
- Full Text
- View/download PDF
49. Properties of Ferrite Garnet (Bi, Lu, Y)3(Fe, Ga)5O12 Thin Film Materials Prepared by RF Magnetron Sputtering
- Author
-
Mohammad Nur-E-Alam, Mikhail Vasiliev, Vladimir Belotelov, and Kamal Alameh
- Subjects
magneto-optics ,magnetic thin films ,optical constants ,Chemistry ,QD1-999 - Abstract
This work is devoted to physical vapor deposition synthesis, and characterisation of bismuth and lutetium-substituted ferrite-garnet thin-film materials for magneto-optic (MO) applications. The properties of garnet thin films sputtered using a target of nominal composition type Bi0.9Lu1.85Y0.25Fe4.0Ga1O12 are studied. By measuring the optical transmission spectra at room temperature, the optical constants and the accurate film thicknesses can be evaluated using Swanepoel’s envelope method. The refractive index data are found to be matching very closely to these derived from Cauchy’s dispersion formula for the entire spectral range between 300 and 2500 nm. The optical absorption coefficient and the extinction coefficient data are studied for both the as-deposited and annealed garnet thin-film samples. A new approach is applied to accurately derive the optical constants data simultaneously with the physical layer thickness, using a combination approach employing custom-built spectrum-fitting software in conjunction with Swanepoel’s envelope method. MO properties, such as specific Faraday rotation, MO figure of merit and MO swing factor are also investigated for several annealed garnet-phase films.
- Published
- 2018
- Full Text
- View/download PDF
50. Visualization of Renewable Energy Powered Automatic Railway Crossing Systems in Bangladesh
- Author
-
Iftekharuzzaman Rifat, Susmita Ghosh, Mohammad Khairul Basher, Mohammad Aminul Islam, Narottam Das, and and Mohammad Nur-E-Alam
- Subjects
energy_fuel_technology - Abstract
Bangladesh's railway system mostly uses typical manual railway crossing technique or boom gates through its 2,955.53 km rail route all over the country. The accidents are frequently happening in the railway crossings due to not having obstacle detectable and quickly operating gate systems, and also for fewer safety measures in the railway crossing. Currently, there are very few automatic railway crossing systems (without obstacle detectors) available, however, all of them are dependent on the national power grid without a backup plan for any emergency cases. Bangladesh is still running a bit behind in the power generation of its consumption, hence it is not possible to have a continuous power supply at all times all over the countryside. We aim to design and develop a smart railway crossing system with an obstacle detector to prevent common types of accidents in the railway crossing points. We design to use two infrared (IR) sensors to operate the railway crossing systems which will be controlled by the Arduino Uno. This newly designed level crossing system will be run with the help of sustainable renewable energy which is cost-effective, eco-friendly, and apply under the national green energy policy towards achieving sustainable development in Bangladesh as a part of the global sustainable goal to face climate change challenges. We have summarized the simulated results of several renewable energy sources including a hybrid system and optimized the Levelized Cost of Energy (LCOE), and the payback periods.
- Published
- 2022
- Full Text
- View/download PDF
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