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16 results on '"Moerloose, Barbara de"'

1. GENOTYPE/PHENOTYPE ASSOCIATIONS IN 174 INDIVIDUALS WITH GERMLINE GATA2 MUTATIONS

Author

Kotmayer, Lili, primary, Kozyra, Emilia, additional, Kaiser, Maximilian, additional, Dworzak, Michael, additional, Moerloose, Barbara De, additional, Starý, Jan, additional, Hasle, Henrik, additional, Jahnukainen, Kirsi, additional, Polychronopoulou, Sophia, additional, Kállay, Krisztián, additional, Smith, Owen, additional, Barzilai, Shlomit, additional, Masetti, Riccardo, additional, Buechner, Jochen, additional, Ussowicz, Marek, additional, Kjollerstrom, Paula, additional, Boďová, Ivana, additional, Kavcic, Marko, additional, Catala, Albert, additional, Turkiewicz, Dominik, additional, Schmugge, Markus, additional, Haas, Valérie De, additional, Voss, Rebecca, additional, Bigas, Anna, additional, Romero, Damia, additional, Bödör, Csaba, additional, Erlacher, Miriam, additional, Giorgetti, Alessandra, additional, Niemeyer, Charlotte, additional, and Wlodarski, Marcin, additional

Published
2023
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2. PB1725: INTERNATIONAL LEUKEMIA TARGET BOARD - A PLATFORM TO DISCUSS AND PRIORITIZE TARGETED TREATMENT OPTIONS FOR PATIENTS WITH RELAPSED/REFRACTORY PEDIATRIC HEMATOLOGICAL MALIGNANCIES (ILTB) – ITCC 107

Author

Ilan, Uri, primary, Boer, Judith M., additional, Burkhardt, Birgit, additional, Delft, Frederik van, additional, Izraeli, Shai, additional, Klusmann, Jan-Henning, additional, Moerloose, Barbara De, additional, Velasco, Pablo, additional, Irving, Julie, additional, Fuster, José Luis, additional, Erdélyi, Dániel, additional, Kulozik, Andreas E, additional, Reinhardt, Dirk, additional, Zwaan, Michel, additional, and den Boer, Monique L., additional

Published
2023
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4. P6 - NPM1 MUTATIONS IN CHILDREN WITH MYELODYSPLASTIC SYNDROME WITH EXCESS BLASTS

Author

Yoshimi, Ayami, Erlacher, Miriam, Noellke, Peter, Ramamoorthy, Senthilkumar, Göhring, Gudrun, Birenboim, Shlomit Barzilai –, Bodova, Ivana, Buechner, Jochen, Catala, Albert, Haas, Valérie De, Moerloose, Barbara De, Dworzak, Michael, Hasle, Henrik, Jahnukainen, Kirsi, Kallay, Krisztian, Kavcic, Marko, Kjollerstrom, Paula, Locatelli, Franco, Masetti, Riccardo, Polychronopoulou, Sophia, Schmugge, Markus, Smith, Owen, Stary, Jan, Turkiewicz, Dominik, Ussowicz, Marek, Rotari, Natalia, Wlodarski, Marcin, Strahm, Brigitte, and Niemeyer, Charlotte

Published
2023
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5. OC 20 - GENOTYPE/PHENOTYPE ASSOCIATIONS IN 174 INDIVIDUALS WITH GERMLINE GATA2 MUTATIONS

Author

Kotmayer, Lili, Kozyra, Emilia, Kaiser, Maximilian, Dworzak, Michael, Moerloose, Barbara De, Starý, Jan, Hasle, Henrik, Jahnukainen, Kirsi, Polychronopoulou, Sophia, Kállay, Krisztián, Smith, Owen, Barzilai, Shlomit, Masetti, Riccardo, Buechner, Jochen, Ussowicz, Marek, Kjollerstrom, Paula, Boďová, Ivana, Kavcic, Marko, Catala, Albert, Turkiewicz, Dominik, Schmugge, Markus, Haas, Valérie De, Voss, Rebecca, Bigas, Anna, Romero, Damia, Bödör, Csaba, Erlacher, Miriam, Giorgetti, Alessandra, Niemeyer, Charlotte, and Wlodarski, Marcin

Published
2023
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6. Deciphering the Non-Coding RNA Landscape of Pediatric Acute Myeloid Leukemia

Author

Vanhooren, Jolien, primary, Camp, Laurens Van, additional, Depreter, Barbara, additional, de Jong, Martijn de, additional, Uyttebroeck, Anne, additional, Van Damme, An Van, additional, Dedeken, Laurence, additional, Dresse, Marie-Françoise, additional, van der Werff ten Bosch, Jutte van der Werff ten, additional, Hofmans, Mattias, additional, Philippé, Jan, additional, De Moerloose, Barbara De, additional, and Lammens, Tim, additional

Published
2022
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7. Publisher Correction : Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes (Nature Medicine, (2021), 27, 10, (1806-1817), )

Author

Sahoo, Sushree S., Pastor, Victor B., Goodings, Charnise, Voss, Rebecca K., Kozyra, Emilia J., Szvetnik, Amina, Noellke, Peter, Dworzak, Michael, Starý, Jan, Locatelli, Franco, Masetti, Riccardo, Schmugge, Markus, De Moerloose, Barbara, Catala, Albert, Kállay, Krisztián, Turkiewicz, Dominik, Hasle, Henrik, Buechner, Jochen, Jahnukainen, Kirsi, Ussowicz, Marek, Polychronopoulou, Sophia, Smith, Owen P., Fabri, Oksana, Barzilai, Shlomit, de Haas, Valerie, Baumann, Irith, Schwarz-Furlan, Stephan, Moerloose, Barbara De, Kallay, Krisztián, Smith, Owen, Haas, Valérie De, Gohring, Gudrun, Niemeyer, Charlotte, Nebral, Karin, Simonitsch-Kluppp, Ingrid, Paepe, Pascale De, Van Roy, Nadine, Campr, Vit, Zemanova, Zuzana, Clasen-Linde, Erik, Plesner, Tine, Schlegelberger, Brigitte, Rudelius, Martina, Manola, Kalliopi, Stefanaki, Kalliopi, Csomor, Judit, Andrikovics, Hajnalka, Betts, David, O’Sullivan, Maureen, Zohar, Yaniv, Jeison, Marta, Vito, Rita De, Pasquali, Francesco, Maldyk, Jadwiga, Haus, Olga, Alaiz, Helena, Kjollerstrom, Paula, Lemos, Luis Mascarenhas de, Bodova, Ivana, Čermák, Martin, Plank, Lukas, Gazic, Barbara, Kavcic, Marko, Podgornik, Helena, Ros, Margarita Llavador, Cervera, Jose, Gengler, Carole, Tchinda, Joelle, Beverloo, Berna, Leguit, Roos, Niewisch, Marena R., Sauer, Martin G., Burkhardt, Birgit, Lang, Peter, Bader, Peter, Beier, Rita, Müller, Ingo, Albert, Michael H., Meisel, Roland, Schulz, Ansgar, Cario, Gunnar, Panda, Pritam K., Wehrle, Julius, Hirabayashi, Shinsuke, Derecka, Marta, Durruthy-Durruthy, Robert, Göhring, Gudrun, Yoshimi-Noellke, Ayami, Ku, Manching, Lebrecht, Dirk, Erlacher, Miriam, Flotho, Christian, Strahm, Brigitte, Niemeyer, Charlotte M., and Wlodarski, Marcin W.

Subjects
Medizin
Abstract

Korrektur zu 10.1038/s41591-021-01511-6

Published
2021

8. Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome

Author

EWOG-MDS, Bortnick, Rachel, Wlodarski, Marcin W., Haas, Valerie de, Moerloose, Barbara de, Dworzak, Michael, Hasle, Henrik, Masetti, Riccardo, Starý, Jan, Turkiewicz, Dominik, Ussowicz, Marek, Kozyra, Emilia J., Albert, Michael, Bader, Peter, Bordon, Victoria, Cario, Gunnar, Beier, Rita, Schulte, Johannes Hubertus, Bresters, Dorine, Müller, Ingo, Pichler, Herbert, Sedlacek, Petr, Sauer, Martin Günther, Zecca, Marco, Göhring, Gudrun, Yoshimi, Ayami, Nöllke, Peter, Erlacher, Miriam, Locatelli, Franco, Niemeyer, Charlotte, Strahm, Brigitte, EWOG-MDS, Bortnick, Rachel, Wlodarski, Marcin W., Haas, Valerie de, Moerloose, Barbara de, Dworzak, Michael, Hasle, Henrik, Masetti, Riccardo, Starý, Jan, Turkiewicz, Dominik, Ussowicz, Marek, Kozyra, Emilia J., Albert, Michael, Bader, Peter, Bordon, Victoria, Cario, Gunnar, Beier, Rita, Schulte, Johannes Hubertus, Bresters, Dorine, Müller, Ingo, Pichler, Herbert, Sedlacek, Petr, Sauer, Martin Günther, Zecca, Marco, Göhring, Gudrun, Yoshimi, Ayami, Nöllke, Peter, Erlacher, Miriam, Locatelli, Franco, Niemeyer, Charlotte, and Strahm, Brigitte

Abstract

GATA2 deficiency is a heterogeneous multi-system disorder characterized by a high risk of developing myelodysplastic syndrome (MDS) and myeloid leukemia. We analyzed the outcome of 65 patients reported to the registry of the European Working Group (EWOG) of MDS in childhood carrying a germline GATA2 mutation (GATA2mut) who had undergone hematopoietic stem cell transplantation (HSCT). At 5 years the probability of overall survival and disease-free survival (DFS) was 75% and 70%, respectively. Non-relapse mortality and relapse equally contributed to treatment failure. There was no evidence of increased incidence of graft-versus-host-disease or excessive rates of infections or organ toxicities. Advanced disease and monosomy 7 (−7) were associated with worse outcome. Patients with refractory cytopenia of childhood (RCC) and normal karyotype showed an excellent outcome (DFS 90%) compared to RCC and −7 (DFS 67%). Comparing outcome of GATA2mut with GATA2wt patients, there was no difference in DFS in patients with RCC and normal karyotype. The same was true for patients with −7 across morphological subtypes. We demonstrate that HSCT outcome is independent of GATA2 germline mutations in pediatric MDS suggesting the application of standard MDS algorithms and protocols. Our data support considering HSCT early in the course of GATA2 deficiency in young individuals.

Published
2021

9. Additional file 1 of The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing

Author

Zubovic, Lorena, Piazza, Silvano, Tebaldi, Toma, Cozzuto, Luca, Palazzo, Giuliana, Sidarovich, Viktoryia, Sanctis, Veronica De, Bertorelli, Roberto, Lammens, Tim, Hofmans, Mattias, Moerloose, Barbara De, Ponomarenko, Julia, Pigazzi, Martina, Masetti, Riccardo, Mecucci, Cristina, Basso, Giuseppe, and Macchi, Paolo

Abstract

Additional file 1. The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing.

Published
2020
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10. Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01

Author

Moerloose, Barbara De, Reedijk, A.M., Bock, Geertruida H. de, Lammens, Tim, Haas, Valerie de, Denys, Barbara, Loo, M. te, Kaspers, Gertjan J.L., Bont, E.S.J.M. de, Moerloose, Barbara De, Reedijk, A.M., Bock, Geertruida H. de, Lammens, Tim, Haas, Valerie de, Denys, Barbara, Loo, M. te, Kaspers, Gertjan J.L., and Bont, E.S.J.M. de

Abstract

Item does not contain fulltext

Published
2019

11. Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

Author

Ghazavi, Farzaneh, primary, Moerloose, Barbara De, additional, Loocke, Wouter Van, additional, Wallaert, Annelynn, additional, Helsmoortel, Hetty H., additional, Ferster, Alina, additional, Bakkus, Marleen, additional, Plat, Geneviève, additional, Delabesse, Eric, additional, Uyttebroeck, Anne, additional, Nieuwerburgh, Filip Van, additional, Deforce, Dieter, additional, Roy, Nadine Van, additional, Speleman, Frank, additional, Benoit, Yves, additional, Lammens, Tim, additional, and Vlierberghe, Pieter Van, additional

Published
2016
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12. Abstract B21: Genetic characterization and therapeutic targeting of MYC translocated pediatric T-cell acute lymphoblastic leukemia

Author

Milani, Gloria, primary, Durinck, Kaat, additional, Matthijssens, Filip, additional, Peirs, Sofie, additional, Pieters, Tim, additional, Reunes, Lindy, additional, Lintermans, Beatrice, additional, Vandamme, Niels, additional, Lammens, Tim, additional, Li, Yunlei, additional, Schwab, Claire, additional, Raimondi, Susana, additional, Moerloose, Barbara De, additional, Benoit, Yves, additional, Berx, Geert, additional, Harrison, Christine, additional, Basso, Giuseppe, additional, Cavé, Helene, additional, Sutton, Rosemary, additional, Asnafi, Vahid, additional, Mullighan, Charles, additional, Meijerink, Jules, additional, Loh, Mignon, additional, and Vlierberghe, Pieter Van, additional

Published
2016
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13. Clinical Impact of Additional Cytogenetic Aberrations, cKIT- and RAS Mutations and Other Factors in Pediatric t(8;21)-AML

Author

Klein, Kim, primary, Kaspers, Gertjan, additional, Harrison, Christine J., additional, Beverloo, Berna, additional, Reedijk, Ardine, additional, Bongers, Mathilda, additional, Cloos, Jacqueline, additional, Pession, Andrea, additional, Reinhardt, Dirk, additional, Zimmermann, Martin, additional, Creutzig, Ursula, additional, Dworzak, Michael, additional, Alonzo, Todd A., additional, Johnston, Donna, additional, Zapotocky, Michal, additional, Moerloose, Barbara De, additional, Fynn, Alcira, additional, Lee, Vincent, additional, Taga, Takashi, additional, Tawa, Akio, additional, Auvrignon, Anne, additional, Zeller, Bernward, additional, Salgado, Carmen, additional, Balwierz, Walentyna, additional, Popa, Alexander, additional, Rubnitz, Jeffrey E, additional, and Gibson, Brenda, additional

Published
2014
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15. Refractory Cytopenia In Childhood (RCC) with Normal Karyotype Is Unlikely to Progress to Advanced MDS Under a Watch and Wait Strategy

Author

Hirabayashi, Shinsuke, primary, Strahm, Brigitte, additional, Schwarz, Stephan, additional, Zecca, Marco, additional, Schmugge, Markus, additional, Dworzak, Michael, additional, van den Heuvel-Eibrink, Marry, additional, Hasle, Henrik, additional, Moerloose, Barbara De, additional, Stary, Jan, additional, Wojcik, Dorota, additional, Furlan, Ingrid, additional, Locatelli, Franco, additional, Baumann, Irith, additional, and Niemeyer, Charlotte M, additional

Published
2010
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