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Your search keyword '"Moerke NJ"' showing total 13 results

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1. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

2. Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases.

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3. Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10.

4. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.

5. Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.

6. Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes.

7. Development of in-cell Western assays using far-red fluorophores.

8. Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation.

9. A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique.

10. Fluorescence Polarization (FP) Assays for Monitoring Peptide-Protein or Nucleic Acid-Protein Binding.

11. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G.

12. Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E.

13. The magnitude of the allosteric conformational transition of aspartate transcarbamylase is altered by mutations.