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Heavy rainfall under the conditions of the changing climate has recently garnered considerable attention. The statistics on heavy daily rainfall offer vital information for assessing present and future extreme events and for clarifying the impacts of global climate variability and change, working to form a favorable background. By analyzing a set of large-ensemble simulations using a global atmospheric model, this study demonstrated that two different physical processes in global climate variability control the interannual fluctuations in the 99th- and 90th-percentile values of summertime daily rainfall (i.e., the potential amounts) on Kyushu Island in western Japan. The 90th-percentile values were closely related to large-scale horizontal moisture transport anomalies due to changes in the subtropical high in the northwestern Pacific, which was usually accompanied by basin-scale warming in the Indian Ocean subsequent to the wintertime El Niño events. The contributions of the sea surface temperatures over the northern Indian Ocean and the eastern tropical Pacific Ocean showed low-frequency modulations, mainly due to the influences of the global warming tendency and the interdecadal variability in the climate system, respectively. In contrast, tropical cyclone activity played a major role in changing the 99th-percentile value. The potentials of both the tropical cyclone intensity and the existence density fluctuated, largely owing to the summertime sea surface temperature over the tropical Pacific, which can be modulated by the El Niño diversity on interdecadal timescales. [ABSTRACT FROM AUTHOR]

We validate the multiyear potential predictability of wintertime heavy precipitation potential in East Asia by combining initialized decadal hindcasts of the global climate model and large ensemble simulations from a high‐resolution global atmospheric model. By analyzing a set of initialized hindcasts, the major predictive components of sea surface temperature (SST) variability beyond interannual timescales are identified as high‐latitudes multidecadal variability and the so‐called trans‐basin variability (TBV). A set of 100 ensemble simulations using a high‐resolution atmospheric model showed a significantly large signal‐to‐noise ratio for the wintertime heavy precipitation potential in East Asia, which is closely related to the TBV. When the SST around the maritime continent is higher, the anomalously low pressure in the northwestern Pacific enhances low‐level cold air transport due to the winter monsoon. Consequently, the resultant weaker baroclinicity in the lower atmosphere reduces storm activity and wintertime heavy precipitation potential in East Asia. Plain Language Summary: Statistical changes in extreme weather and climate events have attracted much attention as potential sources of natural disasters. Numerical experiments to obtain huge ensembles of multiyear predictions with initialization using a high‐resolution model represent a direct approach but a difficult solution for the computational resources available currently. Here, we validated the multiyear potential predictability of wintertime heavy precipitation potential in East Asia, by combining initialized decadal hindcasts of the global climate model and large ensemble simulations from a high‐resolution global atmospheric model. By analyzing a set of initialized hindcasts, we identified one of the major predictive components of sea surface temperature (SST) variability beyond interannual timescales as the so‐called trans‐basin variability (TBV). A set of 100 ensemble simulations using a high‐resolution atmospheric model show a significantly large signal‐to‐noise ratio for the wintertime heavy precipitation potential in East Asia, which is closely related to the TBV. When the SST around the maritime continent is higher, the anomalously low pressure in the northwestern Pacific enhances low‐level cold air transport due to the winter monsoon. Consequently, the resultant weaker baroclinicity in the lower atmosphere reduces storm activity and wintertime heavy precipitation potential in East Asia. Key Points: Multiyear potential predictability is validated for the storm activity and wintertime heavy precipitation potential in East AsiaWe combine initialized decadal hindcasts of global climate model with large ensembles of high‐resolution atmospheric simulationTrans‐basin variability as a predictive climate mode controls the precipitation potential through sea surface temperature changes around the maritime continent [ABSTRACT FROM AUTHOR]

Tropical Pacific sea surface temperature anomalies influence the atmospheric circulation, impacting climate far beyond the tropics. The predictability of the corresponding atmospheric signals is typically limited to less than 1 year lead time. Here we present observational and modelling evidence for multi-year predictability of coherent trans-basin climate variations that are characterized by a zonal seesaw in tropical sea surface temperature and sea-level pressure between the Pacific and the other two ocean basins. State-of-the-art climate model forecasts initialized from a realistic ocean state show that the low-frequency trans-basin climate variability, which explains part of the El Niño Southern Oscillation flavours, can be predicted up to 3 years ahead, thus exceeding the predictive skill of current tropical climate forecasts for natural variability. This low-frequency variability emerges from the synchronization of ocean anomalies in all basins via global reorganizations of the atmospheric Walker Circulation.

Fusarium species (spp.) is frequently found in soil and plant residues and on plant bodies in all climatic zones worldwide. Although there have been few reports of onychomycosis caused by Fusarium spp., it is characterized by drug sensitivity and other characteristics. Here, we report what may be the first case of onychomycosis caused by Fusarium lactis. We analyzed the mycology and characterized previously reported cases of onychomycosis caused by Fusarium spp. A 73‐year‐old otherwise healthy woman presented with discoloration and thickening of her right thumbnail with paronychia. Direct microscopy revealed unevenly swollen hyphae, and a Grocott‐stained nail specimen showed septate hyphae. Based on the morphological features and gene analysis of fungus isolated from the nail, we diagnosed onychomycosis caused by F. lactis belonging to Fusarium fujikuroi species complex. Partial nail removal and topical application of 1% luliconazole solution resolved the condition in 6 months. Minimum inhibitory concentrations for isolated F. lactis showed high sensitivity to luliconazole but not itraconazole or terbinafine. The isolated F. lactis was temperature‐sensitive. A search of the literature revealed 57 cases of onychomycosis caused by Fusarium spp. with delineated clinical characteristics. Since those cases were investigated using morphological and/or molecular methods, we analyzed them by species complex as well as species. Onychomycosis caused by Fusarium spp. is predominantly found on the big toe, with Fusarium solani species complex and Fusarium oxysporum species complex accounting for over 70% of cases. Infection of only one digit with paronychia is a characteristic clinical manifestation of onychomycosis caused by Fusarium spp. Since there has been an increase in instances of molecular determination of Fusarium spp., it is deemed necessary to clarify its clinical and fungal nature. Due to its characteristic drug sensitivity and temperature‐sensitive nature, new treatments are expected to be developed. [ABSTRACT FROM AUTHOR]

Exophiala species cause chromoblastomycosis, mycetoma, and phaeohyphomycosis, which are occasionally fatally in immunocompromised patients. Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) provides rapid and accurate examination of isolated bacteria and some fungal isolates, but the preparation method for filamentous fungi is complicated. In this study, 31 clinical isolates of Exophiala spp. in Japan were identified by MALDI‐TOF MS with a library enriched by adding data. To simplify the sample preparation method, two modified methods were compared with the standard method for filamentous fungi. The agar cultivation sample preparation method reduced the time required for liquid culture and was considered suitable for clinical use. In 30 of 31 clinical isolates of Exophiala spp., the species identified by MALDI‐TOF MS with the highest score matched the species identified by sequencing the internal transcribed spacer region. Exophiala dermatitidis, E. lecanii‐corni, and E. oligosperma were identified above the genus level, while E. jeanselmei and E. xenobiotica were often not identified at the species level. The identification scores tended to be lower for less‐registered strains in the in‐house library. It is suggested that library enrichment and the modified preparation method may facilitate early diagnosis of rare fungal infections by Exophiala spp. in clinical laboratories using MALDI‐TOF MS. [ABSTRACT FROM AUTHOR]