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3 results on '"Mmasa, N."'

1. T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.

Author

Iwase, S.C., Edlefsen, P.T., Bhebhe, L., Motsumi, K., Moyo, S., Happel, A.U., Shao, D., Mmasa, N., Schenkel, S., Gasper, M.A., Dubois, M., Files, M.A., Seshadri, C., Duffy, F., Aitchison, J., Netea, M.G., Jao, J., Cameron, D.W., Gray, C.M., Jaspan, H.B., Powis, K.M., Iwase, S.C., Edlefsen, P.T., Bhebhe, L., Motsumi, K., Moyo, S., Happel, A.U., Shao, D., Mmasa, N., Schenkel, S., Gasper, M.A., Dubois, M., Files, M.A., Seshadri, C., Duffy, F., Aitchison, J., Netea, M.G., Jao, J., Cameron, D.W., Gray, C.M., Jaspan, H.B., and Powis, K.M.

Abstract

Item does not contain fulltext, Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status.

Published
2023

2. Infectious Morbidity and All-cause Mortality of Infants HIV-exposed Uninfected Compared to Infants HIV-unexposed Uninfected in Botswana.

Author

Dubois MM, Jao J, Sun S, Legbedze J, Schenkel S, Mmasa N, Kgole SW, Masasa G, Happel AU, Iwase SC, Haghighat R, Moyo S, Sharma TS, Edlefsen PT, Shao D, Jaspan H, and Powis KM

Subjects
Humans, Botswana epidemiology, Infant, Retrospective Studies, Female, Male, Infant, Newborn, Pregnancy, Hospitalization statistics & numerical data, Prevalence, Infectious Disease Transmission, Vertical statistics & numerical data, Morbidity, Pregnancy Complications, Infectious epidemiology, Pregnancy Complications, Infectious virology, Pregnancy Complications, Infectious mortality, HIV Infections mortality, HIV Infections epidemiology
Abstract

Some studies have reported increased infectious morbidity and all-cause mortality risk among infants HIV-exposed uninfected compared with infants HIV-unexposed uninfected. In a retrospective analysis of infants enrolled in the Botswana-based Tshilo Dikotla study, we found no difference in the prevalence of infectious hospitalizations or deaths from any cause in the first year of life by perinatal HIV exposure., Competing Interests: The authors have no conflicts of interest to disclose., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Published
2025
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3. T-SPOT.TB Reactivity in Southern African Children With and Without in Utero Human Immunodeficiency Virus Exposure.

Author

Iwase SC, Edlefsen PT, Bhebhe L, Motsumi K, Moyo S, Happel AU, Shao D, Mmasa N, Schenkel S, Gasper MA, Dubois M, Files MA, Seshadri C, Duffy F, Aitchison J, Netea MG, Jao J, Cameron DW, Gray CM, Jaspan HB, and Powis KM

Subjects
Infant, Humans, Child, HIV, Prevalence, HIV Infections epidemiology, Tuberculosis prevention & control, Latent Tuberculosis
Abstract

Infants who are human immunodeficiency virus (HIV)-exposed uninfected (iHEU) experience higher risk of infectious morbidity than infants HIV-unexposed uninfected (iHUU). We compared tuberculosis (TB) infection prevalence in 418 Bacillus Calmette-Guérin vaccinated sub-Saharan African iHEU and iHUU aged 9-18 months using T-SPOT.TB. Prevalence of TB infection was low and did not differ by HIV exposure status., Competing Interests: Potential conflicts of interest. All authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed., (© The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America.)

Published
2023
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