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619 results on '"Mizuta Y"'

2. Observation of topological $Z_2$ vortex fluctuations in the frustrated Heisenberg magnet NaCrO$_2$

Author

Tomiyasu, K., Mizuta, Y. P., Matsuura, M., Aoyama, K., and Kawamura, H.

Subjects
Condensed Matter - Strongly Correlated Electrons
Abstract

Spin fluctuations in the triangular-lattice Heisenberg antiferromagnet NaCrO$_2$ are investigated by means of quasi-elastic neutron scattering with high energy resolution and wide energy band. Two components with the following features are captured separately. They are pronounced at intermediate temperatures of 20-50 K. One with quite an extended lifetime corresponding to $\sim$$0.001E_{\rm ex}$ ($E_{\rm ex}$ the exchange energy) nearly disappears at low temperature 10 K, and the other with an extended lifetime $\sim$$0.01E_{\rm ex}$ survives there, identified as free $Z_2$ vortex and $Z_2$-vortex pair, respectively, in harmony with the $Z_2$ vortex theory., Comment: Contents and discussion are expanded, including new figures in Appendix. To appear in Phys. Rev. B

Published
2021
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10. Nonlinear Propagation Theory for Few-to-Mono Optical-Cycle Pulses beyond the Slowly-Varying-Envelope Approximation (SVEA)

Author

Karasawa, N., Mizuta, Y., Fang, X., Lotsch, H. K. V., Rhodes, William T., editor, Asakura, Toshimitsu, editor, Brenner, Karl-Heinz, editor, Hänsch, Theodor W., editor, Kamiya, Takeshi, editor, Krausz, Ferenc, editor, Monemar, Bo, editor, Venghaus, Herbert, editor, Weber, Horst, editor, Weinfurter, Harald, editor, Yamashita, Mikio, editor, Shigekawa, Hidemi, editor, and Morita, Ryuji, editor

Published
2005
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21. Control of dislocation morphology and lattice distortion in Na-flux GaN crystals.

Author

Takeuchi, S., Mizuta, Y., Imanishi, M., Imade, M., Mori, Y., Sumitani, K., Imai, Y., Kimura, S., and Sakai, A.

Subjects
*GALLIUM nitride, *GALLIUM compounds, *LATTICE theory, *SHEAR waves, *TRANSMISSION electron microscopy
Abstract

The dislocation morphology and lattice distortion, including the tilting and twisting of lattice planes, at the Na-flux GaN/seed-GaN interface were investigated using transmission electron microscopy (TEM) and position-dependent nanobeam X-ray diffraction (nanoXRD). The results revealed that the dislocation morphology and lattice distortion in Na-flux GaN at the initial growth stage are strongly influenced by the seed-GaN surface morphology and the growth mode of Na-flux GaN. From the TEM results, one can observe that the formation of dislocation-related etch pits (DREPs) on the seed-GaN surface and the three-dimensional (3D) growth mode for Na-flux GaN give rise to the bending and lateral propagation of dislocations penetrating from the seed-GaN to the Na-flux GaN. This simultaneously results in homogenization of the GaN crystal domain structure as confirmed by nanoXRD. The mechanism responsible for the bending and lateral propagation of dislocations by the formation of DREPs and the 3D growth mode for the Na-flux GaN and the correlation between the dislocation morphology and the lattice distortion are discussed on the basis of TEM and nanoXRD results. [ABSTRACT FROM AUTHOR]

Published
2017
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42. Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions

Author

Minayoshi, Y., Maeda, H., Yanagisawa, H., Hamasaki, K., Mizuta, Y., Nishida, K., Kinoshita, R., Enoki, Y., Imafuku, T., Chuang, Victor, Koga, T., Fujiwara, Y., Takeya, M., Sonoda, K., Wakayama, T., Taguchi, K., Ishima, Y., Ishida, T., Iwakiri, Y., Tanaka, M., Sasaki, Y., Watanabe, H., Otagiri, M., Maruyama, T., Minayoshi, Y., Maeda, H., Yanagisawa, H., Hamasaki, K., Mizuta, Y., Nishida, K., Kinoshita, R., Enoki, Y., Imafuku, T., Chuang, Victor, Koga, T., Fujiwara, Y., Takeya, M., Sonoda, K., Wakayama, T., Taguchi, K., Ishima, Y., Ishida, T., Iwakiri, Y., Tanaka, M., Sasaki, Y., Watanabe, H., Otagiri, M., and Maruyama, T.

Abstract

Because of its multifaceted anti-inflammatory and immunomodulatory effects, delivering type-I interferon to Kupffer cells has the potential to function as a novel type of therapy for the treatment of various types of hepatitis. We report herein on the preparation of a Kupffer cell targeting type-I interferon, an albumin-IFNa2b fusion protein that contains highly mannosylated N-linked oligosaccharide chains, Man-HSA(D494N)-IFNa2b, attached by combining albumin fusion technology and site-directed mutagenesis. The presence of this unique oligosaccharide permits the protein to be efficiently, rapidly and preferentially distributed to Kupffer cells. Likewise IFNa2b, Man-HSA(D494N)-IFNa2b caused a significant induction in the mRNA levels of IL-10, IL-1Ra, PD-L1 in RAW264.7 cells and mouse isolated Kupffer cells, and these inductions were largely inhibited by blocking the interferon receptor. These data indicate that Man-HSA(D494N)-IFNa2b retained the biological activities of type-I interferon. Man-HSA(D494N)-IFNa2b significantly inhibited liver injury in Concanavalin A (Con-A)-induced hepatitis model mice, and consequently improved their survival rate. Moreover, the post-administration of Man-HSA(D494N)-IFNa2b at 2?h after the Con-A challenge also exerted hepato-protective effects. In conclusion, this proof-of-concept study demonstrates the therapeutic effectiveness and utility of Kupffer cell targeting type-I interferon against hepatitis via its anti-inflammatory and immunomodulatory actions.

Published
2018

49. Development of Compact LD Module for 10J at 10Hz Cryocooled Yb:YAG Ceramics Active Mirror Laser Amplifier

Author

Morita, T., primary, Sekine, T., additional, Takeuchi, Y., additional, Hatano, Y., additional, Kurita, T., additional, Tamaoki, Y., additional, Mizuta, Y., additional, Kabeya, Y., additional, Kurata, M., additional, Kawai, K., additional, Muramatsu, Y., additional, Iguchi, T., additional, Iyama, K., additional, Zheng, Y., additional, and Kato, Y., additional

Published
2017
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50. 64J Output Energy in 10ns Pulse from Cryogenic Yb:YAG Ceramics Laser

Author

Sekine, T., primary, Takeuchi, Y., additional, Hatano, Y., additional, Muramatsu, Y., additional, Kurita, T., additional, Morita, T., additional, Mizuta, Y., additional, Kabeya, Y., additional, Kurata, M., additional, Kawai, K., additional, Iguchi, T., additional, Tamaoki, Y., additional, Iyama, K., additional, Zheng, Y., additional, and Kato, Y., additional

Published
2017
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