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9. Effects of BNT162b2 mRNA Covid-19 vaccine on vascular function

Author

Yamaji, Takayuki, primary, Harada, Takahiro, additional, Hashimoto, Yu, additional, Nakano, Yukiko, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Goto, Chikara, additional, Han, Yiming, additional, Mizobuchi, Aya, additional, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2024
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14. Association of Cumulative Low-density Lipoprotein Cholesterol Exposure with Vascular Function

Author

Yamaji, Takayuki, primary, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Nakano, Yukiko, additional, Goto, Chikara, additional, Harada, Takahiro, additional, Mizobuchi, Aya, additional, Tanigawa, Shunsuke, additional, Maruhashi, Tatsuya, additional, and Higashi, Yukihito, additional

Published
2023
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15. Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation

Author

Maruhashi, Tatsuya, primary, Kajikawa, Masato, additional, Kishimoto, Shinji, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Mizobuchi, Aya, additional, Tanigawa, Shunsuke, additional, Yusoff, Farina Mohamad, additional, Nakano, Yukiko, additional, Chayama, Kazuaki, additional, Nakashima, Ayumu, additional, Goto, Chikara, additional, and Higashi, Yukihito, additional

Published
2023
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16. Percentage of mean arterial pressure as a marker of atherosclerosis for detecting patients with coronary artery disease

Author

Maruhashi, Tatsuya, primary, Kajikawa, Masato, additional, Kishimoto, Shinji, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Mizobuchi, Aya, additional, Tanigawa, Shunsuke, additional, Yusoff, Farina Mohamad, additional, Nakano, Yukiko, additional, Chayama, Kazuaki, additional, Nakashima, Ayumu, additional, Goto, Chikara, additional, and Higashi, Yukihito, additional

Published
2023
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17. Trentepohlia brevicellulis comb. et stat. nov. (Trentepohliaceae, Ulvophyceae) found in Japan.

Author

Handa, Shinji, Nakahara‐Tsubota, Miho, Shoda, Izumi, Mizobuchi, Aya, Nakano, Taketo, and Tsubota, Hiromi

Subjects
CYTOPLASMIC filaments, TRANSMISSION electron microscopy, PLASMODESMATA
Abstract

SUMMARY: The family Trentepohliaceae contains many common aerial algae, most widely distributed, particularly in tropical and subtropical regions. Eight species of the genus Trentepohlia have been reported in Japan. We report another taxon, Trentepohlia brevicellulis (Cribb) S. Handa and H. Tsubota comb. et stat. nov., growing on bark in western Honshu, Japan. This alga was previously described as Trentepohlia bosseae var. brevicellulis Cribb. However, the relationship between the bosseae and brevicellulis varieties of T. bosseae could not be ascertained owing to the lack of genetic information for brevicellulis. Therefore, we aimed to examine the detailed morphological characteristics of brevicellulis in wild samples and cultured strains and to review the taxonomy, including systematic information obtained by genetic analysis. Its phylogenetic position was resolved based on 18S rDNA sequence data. It differs from T. bosseae and its variety samoensis in exhibiting a warty zoosporangium surface, an unthickened septum with no central pit field, and a non‐rusty‐brown cell wall. The four key characteristics of T. brevicellulis include a warty layer on the inner surface of the non‐bent side of the suffultory cell wall, an ostiole located near the base of the zoosporangium, curved tapering filaments with thickened cell walls, and globular vegetative spores in the basal portion of the filament. Transmission electron microscopy revealed a pit field wherein simple plasmodesmata were present in the septum. Phylogenetic analysis suggested that this alga and T. bosseae form distinct clades and that T. brevicellulis is separate from T. bosseae. Thus, our study helped redefine the accurate taxonomic position of the species under study as Trentepohlia brevicellulis (Cribb) S. Handa and H. Tsubota comb. et stat. nov., a clade distinct from T. bosseae and reported for the first time in Japan. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy

Author

Hashimoto, Yu, primary, Yamaji, Takayuki, additional, Kitagawa, Toshiro, additional, Nakano, Yukiko, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Tanigawa, Syunsuke, additional, Mizobuchi, Aya, additional, Harada, Takahiro, additional, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Fujita, Asuka, additional, Uchiki, Toshio, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2023
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19. Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors

Author

Kishimoto, Shinji, primary, Oda, Nozomu, additional, Maruhashi, Tatsuya, additional, Tanigawa, Shunsuke, additional, Mizobuchi, Aya, additional, Yusoff, Farina Mohamad, additional, Fujita, Asuka, additional, Uchiki, Toshio, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Nakano, Yukiko, additional, Hirota, Seiko, additional, Yoshinaga, Shinji, additional, Goto, Chikara, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2023
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20. PS-BPC08-9: A COMPARISON OF THE EFFECTS OF ADRENALECTOMY AND TREATMENT WITH EPLERENONE ON VASCULAR FUNCTION IN PATIENTS WITH ALDOSTERONE-PRODUCING ADENOMA

Author

Kishimoto, Shinji, primary, Oki, Kenji, additional, Maruhashi, Tatsuya, additional, Kajikawa, Masato, additional, Mizobuchi, Aya, additional, Harada, Takahiro, additional, Han, Yiming, additional, Hashimoto, Yu, additional, Yusoff, Farina Mohamad, additional, Nakashima, Ayumu, additional, Nakano, Yukiko, additional, and Higashi, Yukihito, additional

Published
2023
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22. Sleep-Disordered Breathing in Commercial Motor Vehicle Drivers

Author

Maruhashi, Tatsuya, primary, Ogawa, Masahiko, additional, Fukunaga, Yasuo, additional, Kitaura, Daisaku, additional, Kajikawa, Masato, additional, Kishimoto, Shinji, additional, Takaeko, Yuji, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Han, Yiming, additional, Mizobuchi, Aya, additional, Mohamad Yusoff, Farina, additional, Chayama, Kazuaki, additional, Nakashima, Ayumu, additional, Goto, Chikara, additional, Yoshimura, Kenichi, additional, Nakano, Yukiko, additional, and Higashi, Yukihito, additional

Published
2022
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23. The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index

Author

Maruhashi, Tatsuya, primary, Kajikawa, Masato, additional, Kishimoto, Shinji, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Mizobuchi, Aya, additional, Tanigawa, Shunsuke, additional, Yusoff, Farina Mohamad, additional, Nakano, Yukiko, additional, Chayama, Kazuaki, additional, Nakashima, Ayumu, additional, Goto, Chikara, additional, Yoshimura, Kenichi, additional, and Higashi, Yukihito, additional

Published
2022
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24. Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension

Author

Yamaji, Takayuki, primary, Harada, Takahiro, additional, Hashimoto, Yu, additional, Nakano, Yukiko, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Goto, Chikara, additional, Mizobuchi, Aya, additional, Tanigawa, Shunsuke, additional, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2022
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25. Vascular Dysfunction Predicts Future Deterioration of Left Ventricular Ejection Fraction in Patients with Heart Failure with Mildly Reduced Ejection Fraction

Author

Kishimoto, Shinji, primary, Maruhashi, Tatsuya, additional, Kajikawa, Masato, additional, Harada, Takahiro, additional, Yamaji, Takayuki, additional, Han, Yiming, additional, Mizobuchi, Aya, additional, Hashimoto, Yu, additional, Yoshimura, Kenichi, additional, Nakano, Yukiko, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Yusoff, Farina Mohamad, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2021
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26. Short stature is associated with low flow-mediated vasodilation in Japanese men

Author

Harada, Takahiro, primary, Kajikawa, Masato, additional, Maruhashi, Tatsuya, additional, Kishimoto, Shinji, additional, Yamaji, Takayuki, additional, Han, Yiming, additional, Mizobuchi, Aya, additional, Hashimoto, Yu, additional, Yoshimura, Kenichi, additional, Nakano, Yukiko, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Yusoff, Farina Mohamad, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2021
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27. Relationship between Hemoglobin A1c Level and Flow‐mediated Vasodilation in Patients with Type 2 Diabetes Mellitus Receiving Antidiabetic Drugs

Author

Yamaji, Takayuki, primary, Harada, Takahiro, additional, Hashimoto, Yu, additional, Nakano, Yukiko, additional, Kajikawa, Masato, additional, Yoshimura, Kenichi, additional, Aoki, Gaku, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Mizobuchi, Aya, additional, Han, Yiming, additional, Yusoff, Farina Mohamad, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2021
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28. A body shape index is associated with endothelial dysfunction in both men and women

Author

Kajikawa, Masato, primary, Maruhashi, Tatsuya, additional, Kishimoto, Shinji, additional, Yamaji, Takayuki, additional, Harada, Takahiro, additional, Hashimoto, Yu, additional, Han, Yiming, additional, Mizobuchi, Aya, additional, Aoki, Gaku, additional, Yoshimura, Kenichi, additional, Chayama, Kazuaki, additional, Goto, Chikara, additional, Yusoff, Farina Mohamad, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2021
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29. Low-intensity pulsed ultrasound decreases major amputation in patients with critical limb ischemia: 5-year follow-up study

Author

Mohamad Yusoff, Farina, primary, Kajikawa, Masato, additional, Yamaji, Takayuki, additional, Takaeko, Yuji, additional, Hashimoto, Yu, additional, Mizobuchi, Aya, additional, Han, Yiming, additional, Kishimoto, Shinji, additional, Maruhashi, Tatsuya, additional, Nakashima, Ayumu, additional, and Higashi, Yukihito, additional

Published
2021
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30. Relationship between hemoglobin A1c level and flow‐mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs.

Author

Yamaji, Takayuki, Harada, Takahiro, Hashimoto, Yu, Nakano, Yukiko, Kajikawa, Masato, Yoshimura, Kenichi, Aoki, Gaku, Chayama, Kazuaki, Goto, Chikara, Mizobuchi, Aya, Han, Yiming, Yusoff, Farina Mohamad, Kishimoto, Shinji, Maruhashi, Tatsuya, Nakashima, Ayumu, and Higashi, Yukihito

Subjects
TYPE 2 diabetes, VASCULAR smooth muscle, VASODILATION, HYPOGLYCEMIC agents, HEMOGLOBINS
Abstract

Aims/Introduction: Diabetes mellitus is associated with endothelial dysfunction. However, it is still controversial as to whether antidiabetic drug treatment affects endothelial function. The purpose of this study was to evaluate the relationships of the hemoglobin A1c (HbA1c) level with flow‐mediated vasodilation (FMD) and nitroglycerine‐induced vasodilation (NID) in patients with type 2 diabetes mellitus who are receiving antidiabetic drugs. Materials and Methods: The FMD was measured in 866 patients with type 2 diabetes mellitus who were receiving antidiabetic drugs (625 men and 241 women; mean age: 62 ± 10 years). The patients were divided into four groups according to HbA1c levels: <6.5, 6.5–6.9, 7.0–7.9, and ≥8.0%. Results: There was an inverted U‐shaped pattern of association of the HbA1c level with the FMD at an HbA1c level of about 7% of the peak of FMD in patients with type 2 diabetes mellitus who were receiving antidiabetic drugs. The FMD was significantly smaller in the HbA1c <6.5% group than in the HbA1c 6.5–6.9% group and the HbA1c 7.0–7.9% group (P < 0.001 and P < 0.001, respectively). The FMD values were similar in the HbA1c <6.5% group and HbA1c ≥8.0% group (P = 0.10). There were no significant differences in NID among the four groups (P = 0.98). Conclusions: These findings suggest that a low HbA1c <6.5% as well as a high HbA1c ≥8.0% is associated with endothelial dysfunction in patients with type 2 diabetes mellitus who are receiving antidiabetic drugs and that vascular smooth muscle function is similar in such patients regardless of the HbA1c level. [ABSTRACT FROM AUTHOR]

Published
2022
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31. A Body Shape Index as a Simple Anthropometric Marker of Abdominal Obesity and Risk of Cardiovascular Events.

Author

Kajikawa M, Maruhashi T, Kishimoto S, Yamaji T, Harada T, Saito Y, Mizobuchi A, Tanigawa S, Nakano Y, Chayama K, Goto C, Yusoff FM, Nakashima A, and Higashi Y

Abstract

Background: A Body Shape Index (ABSI) has been reported to have associations with cardiovascular risk factors. However, there is no information on the association between ABSI and incidence of cardiovascular events., Methods: We investigated the associations between ABSI and first major cardiovascular events (death from cardiovascular disease, nonfatal acute coronary syndrome, and nonfatal stroke) in 1857 subjects from the database of Flow-Mediated Dilation Japan registry and from Hiroshima University Vascular Function registry., Results: The areas under the curves of ABSI to predict the first major cardiovascular events were superior to BMI (men: P=0.032, women: P=0.015) and waist circumference in women (men: P=0.078, women: P=0.002). The subjects were divided into two groups based on the cutoff value of ABSI for predicting first major cardiovascular events: a low ABSI group (<0.0822 in men and <0.0814 in women) and a high ABSI group (≥0.0822 in men and ≥0.0814 in women). During a median follow-up period of 41.6 months, 56 subjects died (23 from cardiovascular causes), 16 had nonfatal acute coronary syndrome, and 14 had nonfatal stroke. The Kaplan-Meier curves for first major cardiovascular events were significantly different between the two groups (men, P<0.001; women, P<0.001). Multivariate analysis revealed that high ABSI remained an independent predictor of first major cardiovascular events (men: hazard ratio, 2.33; 95% CI, 1.07 to 5.06; P=0.033; women: hazard ratio, 8.33; 95% CI, 1.06 to 65.49; P=0.044)., Conclusions: High ABSI is independently associated with incidence of cardiovascular events. ABSI calculation should be performed for evaluation of risk of cardiovascular events., (© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)

Published
2024
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