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152 results on '"Mizobe, Toshiki"'

6. The RACHS-1 risk category can be a predictor of perioperative recovery in Asian pediatric cardiac surgery patients

Author

Nakayama, Yoshinobu, Shibasaki, Masayuki, Shime, Nobuaki, Nakajima, Yasufumi, Mizobe, Toshiki, and Sawa, Teiji

Subjects
Heart -- Surgery, Treatment outcome -- Research -- Health aspects, Cardiac patients -- Prognosis -- Patient outcomes -- Health aspects, Health
Abstract

Purpose The Risk Adjustment for Congenital Heart Surgery (RACHS-1) classification was originally designed to facilitate the prediction of in-hospital mortality for pediatric cardiac surgery patients. However, there have been few reports on clinical outcomes predicted by the RACHS-1 category, especially in an Asian population. The aim of this study was to determine whether RACHS-1 classification can predict patient outcomes. Methods A total of 580 pediatric cardiac surgery procedures performed from January 2005 to December 2009 were retrospectively classified into the six RACHS-1 categories. The association between RACHS-1 category and clinical outcomes, including length of catecholamine requirement, mechanical ventilation time, intensive care unit stay, and in-hospital mortality, were examined. Results The frequencies of RACHS-1 categories in the study population were: category 1, 10.7%; category 2, 36.7%; category 3, 42.8%; category 4, 6.6%; category 5, 0.0%; category 6, 3.3%. There was a significant linear correlation between RACHS-1 category and in-hospital mortality (r = 0.96, p < 0.001). Kaplan-Meier analysis demonstrated that length of catecholamine infusion, mechanical ventilation time, and ICU stay were significantly different (p < 0.05) in the different RACHS-1 categories, except for those between category 4 and 6 (p = 0.09). Conclusions Based on the results of our analysis, we conclude that the RACHS-1 stratification system can predict in-hospital mortality and patient outcomes in patients undergoing pediatric cardiac surgery. Keywords RACHS-1 * In-hospital mortality * ICU stay * Mechanical ventilation time * Catecholamine requirement, Introduction Establishing a tool that can effectively predicting mortality and morbidity for pediatric congenital cardiac surgery patients is clinically practical. The Risk Adjustment for Congenital Heart Surgery (RACHS-1) classification system [...]

Published
2013
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19. Flow-dynamics assessment of mitral-valve surgery by intraoperative vector flow mapping

Author

Akiyama, Koichi, primary, Nakamura, Naotoshi, additional, Itatani, Keiichi, additional, Naito, Yoshifumi, additional, Kinoshita, Mao, additional, Shimizu, Masaru, additional, Hamaoka, Saeko, additional, Kato, Hideya, additional, Yasumoto, Hiroaki, additional, Nakajima, Yasufumi, additional, Mizobe, Toshiki, additional, Numata, Satoshi, additional, Yaku, Hitoshi, additional, and Sawa, Teiji, additional

Published
2017
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21. Baroreflex modulation of peripheral vasoconstriction during progressive hypothermia in anesthetized humans

Author

NAKAJIMA, YASUFUMI, MIZOBE, TOSHIKI, TAKAMATA, AKIRA, and TANAKA, YOSHIFUMI

Subjects
Vasoconstriction -- Physiological aspects, Hypothermia -- Physiological aspects, Cardiovascular system -- Physiological aspects, Blood flow -- Physiological aspects, Body temperature -- Regulation, Biological sciences
Abstract

Nakajima, Yasufumi, Toshiki Mizobe, Akira Takamata, and Yoshifumi Tanaka. Baroreflex modulation of peripheral vasoconstriction during progressive hypothermia in anesthetized humans. Am J Physiol Regulatory Integrative Comp Physiol 279: R1430-R1436, 2000.--Mild hypothermia is a major concomitant of surgery under general anesthesia. We examined the hypothesis that baroreceptor loading/unloading modifies thermoregulatory peripheral vasoconstriction and, consequently, body core temperature in subjects undergoing lower abdominal surgery with general anesthesia. Thirty-six patients were divided into four groups: control group (C), applied positive end-expiratory pressure (PEEP; 10 cm[H.sub.2]O) group (P), applied leg-up position group (L), and a group of leg-up position patients with PEEP starting 90 min after induction of anesthesia (L + P). The esophageal temperature ([T.sub.es]) and the forearm-fingertip temperature gradient, as an index of peripheral vasoconstriction, were monitored for 3 h after induction of anesthesia. Mean arterial pressure and pulse pressure did not change during the study in any group. The change in right atrial transmural pressure from the baseline value was 0.3 [+ or -] 0.1 mmHg in C, -3.0 [+ or -] 0.5 mmHg in P, and 2.3 [+ or -] 0.4 mmHg in L (P [is less than] 0.01). The change in [T.sub.es] at the end of the study was -1.7 [+ or -] 0.1 (35.1 [+ or -] 0.1) [degrees] C in C, -1.1 [+ or -] 0.1 (35.7 [+ or -] 0.1) [degrees] C in P, and -2.7 [+ or -] 0.1 (34.1 [+ or -] 0.1) [degrees] C in L, showing significant differences (P [is less than] 0.01). The [T.sub.es] threshold for thermal peripheral vasoconstriction was 35.6 [+ or -] 0.1 [degrees] C in C, 36.2 [+ or -] 0.2 [degrees] C in P, and 34.8 [+ or -] 0.2 [degrees] C in L (P [is less than] 0.01). Excessive [T.sub.es] decrease in the leg-up-position operation was attenuated by applying PEEP (L + P group; P [is less than] 0.05). Our data indicate that baroreceptor loading augments and unloading prevents perioperative hypothermia in anesthetized and paralyzed subjects by reducing and increasing the body temperature threshold for peripheral vasoconstriction, respectively. cardiovascular regulation; thermoregnlation; peripheral blood flow; core temperature threshold

Published
2000

22. MITRAL VALVE REPLACEMENT IMPAIRS LEFT VENTRICULAR BLOOD FLOW

Author

Akiyama, Koichi, primary, Itatani, Keiichi, additional, Kinoshita, Mao, additional, Shimizu, Masaru, additional, Hamaoka, Saeko, additional, Kato, Hideya, additional, Naito, Yoshifumi, additional, Nakajima, Yasufumi, additional, Numata, Satoshi, additional, Mizobe, Toshiki, additional, Yaku, Hitoshi, additional, and Sawa, Teiji, additional

Published
2016
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39. Upright Posture Reduces Thermogenesis and Augments Core Hypothermia

Author

Nakajima, Yasufumi, primary, Takamata, Akira, additional, Ito, Tomoyuki, additional, Sessler, Daniel I., additional, Kitamura, Yoshihiro, additional, Shimosato, Goshun, additional, Taniguchi, Satoshi, additional, Matsuyama, Hiroki, additional, Tanaka, Yoshifumi, additional, and Mizobe, Toshiki, additional

Published
2002
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