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229 results on '"Miyo, Masaaki"'

1. ctDNA-based molecular residual disease and survival in resectable colorectal cancer

Author

Nakamura, Yoshiaki, Watanabe, Jun, Akazawa, Naoya, Hirata, Keiji, Kataoka, Kozo, Yokota, Mitsuru, Kato, Kentaro, Kotaka, Masahito, Kagawa, Yoshinori, Yeh, Kun-Huei, Mishima, Saori, Yukami, Hiroki, Ando, Koji, Miyo, Masaaki, Misumi, Toshihiro, Yamazaki, Kentaro, Ebi, Hiromichi, Okita, Kenji, Hamabe, Atsushi, Sokuoka, Hiroki, Kobayashi, Satoshi, Laliotis, George, Aushev, Vasily N., Sharma, Shruti, Jurdi, Adham, Liu, Minetta C., Aleshin, Alexey, Rabinowitz, Matthew, Bando, Hideaki, Taniguchi, Hiroya, Takemasa, Ichiro, Kato, Takeshi, Kotani, Daisuke, Mori, Masaki, Yoshino, Takayuki, and Oki, Eiji

Published
2024
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2. Predicting Generalization of AI Colonoscopy Models to Unseen Data

Author

Shor, Joel, McNeil, Carson, Intrator, Yotam, Ledsam, Joseph R, Yamano, Hiro-o, Tsurumaru, Daisuke, Kayama, Hiroki, Hamabe, Atsushi, Ando, Koji, Ota, Mitsuhiko, Ogino, Haruei, Nakase, Hiroshi, Kobayashi, Kaho, Miyo, Masaaki, Oki, Eiji, Takemasa, Ichiro, Rivlin, Ehud, and Goldenberg, Roman

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Artificial Intelligence, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Computers and Society
Abstract

$\textbf{Background}$: Generalizability of AI colonoscopy algorithms is important for wider adoption in clinical practice. However, current techniques for evaluating performance on unseen data require expensive and time-intensive labels. $\textbf{Methods}$: We use a "Masked Siamese Network" (MSN) to identify novel phenomena in unseen data and predict polyp detector performance. MSN is trained to predict masked out regions of polyp images, without any labels. We test MSN's ability to be trained on data only from Israel and detect unseen techniques, narrow-band imaging (NBI) and chromendoscoy (CE), on colonoscopes from Japan (354 videos, 128 hours). We also test MSN's ability to predict performance of Computer Aided Detection (CADe) of polyps on colonoscopies from both countries, even though MSN is not trained on data from Japan. $\textbf{Results}$: MSN correctly identifies NBI and CE as less similar to Israel whitelight than Japan whitelight (bootstrapped z-test, |z| > 496, p < 10^-8 for both) using the label-free Frechet distance. MSN detects NBI with 99% accuracy, predicts CE better than our heuristic (90% vs 79% accuracy) despite being trained only on whitelight, and is the only method that is robust to noisy labels. MSN predicts CADe polyp detector performance on in-domain Israel and out-of-domain Japan colonoscopies (r=0.79, 0.37 respectively). With few examples of Japan detector performance to train on, MSN prediction of Japan performance improves (r=0.56). $\textbf{Conclusion}$: Our technique can identify distribution shifts in clinical data and can predict CADe detector performance on unseen data, without labels. Our self-supervised approach can aid in detecting when data in practice is different from training, such as between hospitals or data has meaningfully shifted from training. MSN has potential for application to medical image domains beyond colonoscopy.

Published
2024

6. Influence of the rotation of the diverting loop ileostomy in rectal cancer surgery on small-bowel obstruction: A multicenter prospective study conducted by the Clinical Study Group of Osaka University, Colorectal Group

Author

Miyo, Masaaki, Uemura, Mamoru, Ozato, Yuki, Nishimura, Junichi, Nakata, Ken, Suzuki, Yozo, Kagawa, Yoshinori, Hata, Taishi, Munakata, Koji, Tei, Mitsuyoshi, Sawada, Genta, Yoshioka, Shinichi, Takahashi, Yusuke, Oba, Koji, Hata, Tsuyoshi, Ogino, Takayuki, Miyoshi, Norikatsu, Yamamoto, Hirofumi, Murata, Kohei, Doki, Yuichiro, and Eguchi, Hidetoshi

Published
2025
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7. Circulating tumor DNA for predicting radiographic and pathologic response to total neoadjuvant therapy in locally advanced rectal cancer: ENSEMBLE-1.

Author

Kagawa, Yoshinori, Watanabe, Jun, Uemura, Mamoru, Ando, Koji, Inoue, Akira, Nishizawa, Yujiro, Suwa, Yusuke, Chida, Keigo, Hata, Tsuyoshi, Sekido, Yuki, Nakanishi, Ryota, Okuya, Koichi, Miyo, Masaaki, Oba, Koji, Laliotis, George, Nakamura, Yoshiaki, Bando, Hideaki, Yoshino, Takayuki, Takemasa, Ichiro, and Oki, Eiji

Published
2024
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12. Long-term survival differences between sevoflurane and propofol use in general anesthesia for gynecologic cancer surgery

Author

Takeyama, Eriko, Miyo, Masaaki, Matsumoto, Hisanori, Tatsumi, Kenji, Amano, Eizo, Hirao, Motohiro, and Shibuya, Hiromi

Subjects
Medical research -- Analysis -- Usage, Medicine, Experimental -- Analysis -- Usage, Cancer patients -- Prognosis, Diseases -- Relapse, Phenols -- Usage, Anesthetics -- Usage, Cancer -- Prognosis, Anesthesia -- Analysis -- Usage, Ovarian cancer -- Prognosis, Surgery -- Usage -- Analysis, Health
Abstract

Background This study aimed to evaluate the influence of anesthetic management with propofol or sevoflurane on the prognosis of patients undergoing gynecologic cancer surgery. Methods This retrospective cohort study included patients who underwent gynecologic cancer (cervical, endometrial, and ovarian cancer) surgery between 2006 and 2018 at the National Hospital Organization Osaka National Hospital. Patients were grouped according to anesthesia type for maintenance of anesthesia: propofol or sevoflurane. After propensity score matching, Kaplan-Meier survival curves were constructed for overall survival, cancer-specific survival, and recurrence-free survival. Univariate and multivariate cox regression models were used to compare hazard ratios for recurrence-free survival. Results A total of 193 patients with propofol and 94 with sevoflurane anesthesia were eligible for analysis. After propensity score matching, 94 patients remained in each group. The sevoflurane group showed significantly lower survival rates than the propofol group with respect to 10-year overall survival (89.3% vs. 71.6%; p = 0.007), 10-year cancer-specific survival (91.0% vs 80.2%; p = 0.039), and 10-year recurrence-free survival (85.6% vs. 67.7%; p = 0.008). Sevoflurane anesthesia was identified as an independent risk factor for recurrence-free survival. Furthermore, distant recurrence was significantly more frequent in the sevoflurane group than in the propofol group (p < 0.001). Conclusion In patients undergoing gynecologic cancer surgery, sevoflurane anesthesia was associated with worse overall, cancer-specific, and recurrence-free survival than propofol anesthesia., Author(s): Eriko Takeyama [sup.1], Masaaki Miyo [sup.2], Hisanori Matsumoto [sup.3], Kenji Tatsumi [sup.3], Eizo Amano [sup.1], Motohiro Hirao [sup.2], Hiromi Shibuya [sup.1] Author Affiliations: (1) grid.416803.8, 0000 0004 0377 7966, [...]

Published
2021
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13. Association of circulating tumor DNA (ctDNA) molecular disease (MRD) detection with lymph node metastasis after local excision of pathological T1 colorectal cancer: First results from DENEB, a CIRCULATE-Japan GALAXY substudy.

Author

Miyo, Masaaki, primary, Kato, Takeshi, additional, Nakamura, Yoshiaki, additional, Mishima, Saori, additional, Bando, Hideaki, additional, Yukami, Hiroki, additional, Ando, Koji, additional, Watanabe, Jun, additional, Akazawa, Naoya, additional, Yokota, Mitsuru, additional, Kagawa, Yoshinori, additional, Jurdi, Adham A, additional, Liu, Minetta C., additional, Oba, Koji, additional, Taniguchi, Hiroya, additional, Kotani, Daisuke, additional, Oki, Eiji, additional, Takemasa, Ichiro, additional, Mori, Masaki, additional, and Yoshino, Takayuki, additional

Published
2024
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14. Cylindrical abdominoperineal resection for rectal cancer using the Hugo RAS system: The first ever case report for rectal cancer.

Author

Toyota, Maho, Miyo, Masaaki, Okuya, Koichi, Ito, Tatsuya, Akizuki, Emi, Noda, Ai, Ogawa, Tadashi, Ishii, Masayuki, Miura, Ryo, Ichihara, Momoko, Kimura, Akina, and Takemasa, Ichiro

Subjects
*ABDOMINOPERINEAL resection, *ONCOLOGIC surgery, *PELVIS, *RECTAL surgery, *RECTAL cancer, *ANAL cancer, *NAVEL
Abstract

In May 2023, the Hugo RAS system obtained pharmaceutical approval for use in gastroenterological surgery in Japan. It is expected to be particularly effective in rectal cancer surgery, which require the manipulation of the deep pelvic cavity and communication with surgeons operating from the intraperitoneal and anal approaches. A 68‐year‐old woman presented to our hospital with bloody stools and was diagnosed with cStage I (cT2N0M0) rectal cancer and underwent abdominoperineal resection employing the Hugo RAS system. Two arm carts were placed on the left and right lateral sides with an interleg space, and trocars were placed in a straight line between the right superior iliac spine and umbilicus. Herein, we report the first abdominoperineal resection for rectal cancer using the Hugo RAS system. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Tele‐proctoring for minimally invasive surgery across Japan: An initial step toward a new approach to improving the disparity of surgical care and supporting surgical education

Author

Takemasa, Ichiro, primary, Okuya, Koichi, additional, Okita, Kenji, additional, Akizuki, Emi, additional, Miyo, Masaaki, additional, Ishii, Masayuki, additional, Miura, Ryo, additional, Ichihara, Momoko, additional, Takahiro, Korai, additional, Oki, Eiji, additional, Takatsuki, Mitsuhisa, additional, Eguchi, Susumu, additional, Ichikawa, Daisuke, additional, Kitagawa, Yuko, additional, Sakai, Yoshiharu, additional, and Mori, Masaki, additional

Published
2023
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16. O4-5 Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: GALAXY study in the CIRCULATE-Japan

Author

Mishima, Saori, primary, Kotani, Daisuke, additional, Nakamura, Yoshiaki, additional, Bando, Hideaki, additional, Miyo, Masaaki, additional, Hamabe, Atsushi, additional, Watanabe, Jun, additional, Hirata, Keiji, additional, Akazawa, Naoya, additional, Kataoka, Kozo, additional, Yeh, Kun-Huei, additional, Laliotis, George, additional, Jurdi, Adham, additional, Liu, Minetta, additional, Taniguchi, Hiroya, additional, Takemasa, Ichiro, additional, Kato, Takeshi, additional, Yoshino, Takayuki, additional, and Oki, Eiji, additional

Published
2023
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17. Postoperative circulating tumor DNA-based molecular residual disease in patients with BRAF V600E and MSI-H colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan.

Author

Watanabe, Jun, primary, Oki, Eiji, additional, Kotani, Daisuke, additional, Nakamura, Yoshiaki, additional, Mishima, Saori, additional, Bando, Hideaki, additional, Yukami, Hiroki, additional, Ando, Koji, additional, Miyo, Masaaki, additional, Hirata, Keiji, additional, Akazawa, Naoya, additional, Yeh, Kun-Huei, additional, Laliotis, George, additional, Jurdi, Adham A, additional, Liu, Minetta, additional, Taniguchi, Hiroya, additional, Takemasa, Ichiro, additional, Kato, Takeshi, additional, Mori, Masaki, additional, and Yoshino, Takayuki, additional

Published
2023
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18. Protocol of the QUATTRO-II study: a multicenter randomized phase II study comparing CAPOXIRI plus bevacizumab with FOLFOXIRI plus bevacizumab as a first-line treatment in patients with metastatic colorectal cancer

Author

Miyo, Masaaki, Kato, Takeshi, Yoshino, Takayuki, Yamanaka, Takeharu, Bando, Hideaki, Satake, Hironaga, Yamazaki, Kentaro, Taniguchi, Hiroya, Oki, Eiji, Kotaka, Masahito, Oba, Koji, Miyata, Yoshinori, Muro, Kei, Komatsu, Yoshito, Baba, Hideo, and Tsuji, Akihito

Published
2020
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19. Tele‐proctoring for minimally invasive surgery across Japan: An initial step toward a new approach to improving the disparity of surgical care and supporting surgical education.

Author

Takemasa, Ichiro, Okuya, Koichi, Okita, Kenji, Akizuki, Emi, Miyo, Masaaki, Ishii, Masayuki, Miura, Ryo, Ichihara, Momoko, Takahiro, Korai, Oki, Eiji, Takatsuki, Mitsuhisa, Eguchi, Susumu, Ichikawa, Daisuke, Kitagawa, Yuko, Sakai, Yoshiharu, and Mori, Masaki

Subjects
MINIMALLY invasive procedures, SURGICAL education, MEDICAL personnel, HEALTH equity, TELECOMMUNICATION systems, TELERADIOLOGY, NURSES' aides, RURAL health services
Abstract

Aim: The aim of this study was to verify the clinical feasibility of tele‐proctoring using our ultra‐low latency communication system with shared internet access. Methods: Connections between two multiple remote locations at various distances were established through the TELEPRO® tele‐proctoring system. The server records the latency between the two locations for tele‐proctoring using the annotations. Questionnaires were administered to the surgeons, assistants, and medical staff. Respondents rated the quickness and quality of communication in terms of latency and disturbances in the audio, video, and usefulness of the live telestrations with annotation. Results: Seven hospitals tele‐proctored with Sapporo Medical University between January 2021 and September 2022. The median latency of annotation between the two locations ranged from 24.5 to 48.5 ms. No major technological problems occurred, such as streaming interruption, loss of video or audio, poor resolution. The video encoding time was 10 ms, and its decoding time was 0.8 ms. The total latency positively correlated with the distance between two locations (R = 0.55, p < 0.01). The quality of communication regarding latency, disturbance, and surgical education with intraoperative annotative instructions showed similar trends, with perfectly fine being the most common response. No significant differences in surgical quality, educational effect, or social impact were observed between the latency ≥30 and <30 ms groups for whether the size of latency affects surgical education. Conclusion: The feasibility of the tele‐proctoring system is expected to be a sustainable approach to help education for young surgeons and surgical supports in rural areas, thereby reducing disparities in health care. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Right hemicolectomy for ascending colon cancer using the hinotori surgical robot system: The first ever case report for colon cancer

Author

Miyo, Masaaki, primary, Okita, Kenji, additional, Okuya, Koichi, additional, Ito, Tatsuya, additional, Akizuki, Emi, additional, Ogawa, Tadashi, additional, Ishii, Masayuki, additional, Miura, Ryo, additional, Ichihara, Momoko, additional, Korai, Takahiro, additional, Kimura, Akina, additional, and Takemasa, Ichiro, additional

Published
2023
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21. Supplemental Figures S1-S13 and Tables S1-S3 from Targeting MUC1-C Inhibits TWIST1 Signaling in Triple-Negative Breast Cancer

Author

Hata, Tsuyoshi, primary, Rajabi, Hasan, primary, Yamamoto, Masaaki, primary, Jin, Caining, primary, Ahmad, Rehan, primary, Zhang, Yan, primary, Kui, Ling, primary, Li, Wei, primary, Yasumizu, Yota, primary, Hong, Deli, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Maeda, Takahiro, primary, Suzuki, Yozo, primary, Takahashi, Hidekazu, primary, Samur, Mehmet, primary, and Kufe, Donald, primary

Published
2023
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22. Data from Targeting MUC1-C Inhibits TWIST1 Signaling in Triple-Negative Breast Cancer

Author

Hata, Tsuyoshi, primary, Rajabi, Hasan, primary, Yamamoto, Masaaki, primary, Jin, Caining, primary, Ahmad, Rehan, primary, Zhang, Yan, primary, Kui, Ling, primary, Li, Wei, primary, Yasumizu, Yota, primary, Hong, Deli, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Maeda, Takahiro, primary, Suzuki, Yozo, primary, Takahashi, Hidekazu, primary, Samur, Mehmet, primary, and Kufe, Donald, primary

Published
2023
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24. Data from MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells

Author

Yamamoto, Masaaki, primary, Jin, Caining, primary, Hata, Tsuyoshi, primary, Yasumizu, Yota, primary, Zhang, Yan, primary, Hong, Deli, primary, Maeda, Takahiro, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Suzuki, Yozo, primary, Hinohara, Kunihiko, primary, Rajabi, Hasan, primary, and Kufe, Donald, primary

Published
2023
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26. The proteasome activities of LPACs and non-LPACs. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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28. The list of universally elevated genes in LPACｓ of all cell lines using microarray analysis. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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29. Data from MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells

Author

Hata, Tsuyoshi, primary, Rajabi, Hasan, primary, Takahashi, Hidekazu, primary, Yasumizu, Yota, primary, Li, Wei, primary, Jin, Caining, primary, Long, Mark D., primary, Hu, Qiang, primary, Liu, Song, primary, Fushimi, Atsushi, primary, Yamashita, Nami, primary, Kui, Ling, primary, Hong, Deli, primary, Yamamoto, Masaaki, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Maeda, Takahiro, primary, Suzuki, Yozo, primary, Samur, Mehmet K., primary, and Kufe, Donald, primary

Published
2023
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30. Analysis of LPACs and non-LPACs based on various stem cell markers. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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31. Supplementary Material from MUC1-C Activates the NuRD Complex to Drive Dedifferentiation of Triple-Negative Breast Cancer Cells

Author

Hata, Tsuyoshi, primary, Rajabi, Hasan, primary, Takahashi, Hidekazu, primary, Yasumizu, Yota, primary, Li, Wei, primary, Jin, Caining, primary, Long, Mark D., primary, Hu, Qiang, primary, Liu, Song, primary, Fushimi, Atsushi, primary, Yamashita, Nami, primary, Kui, Ling, primary, Hong, Deli, primary, Yamamoto, Masaaki, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Maeda, Takahiro, primary, Suzuki, Yozo, primary, Samur, Mehmet K., primary, and Kufe, Donald, primary

Published
2023
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32. The confirmation of stable ZsGreen expression in CRC cell lines. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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33. The validation of over-expression of EID3 and down- regulation of EID3. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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34. Supplementary Figures from MUC1-C Integrates Chromatin Remodeling and PARP1 Activity in the DNA Damage Response of Triple-Negative Breast Cancer Cells

Author

Yamamoto, Masaaki, primary, Jin, Caining, primary, Hata, Tsuyoshi, primary, Yasumizu, Yota, primary, Zhang, Yan, primary, Hong, Deli, primary, Maeda, Takahiro, primary, Miyo, Masaaki, primary, Hiraki, Masayuki, primary, Suzuki, Yozo, primary, Hinohara, Kunihiko, primary, Rajabi, Hasan, primary, and Kufe, Donald, primary

Published
2023
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35. Relationship between EID3 expression and clinicopathological factors in patients with colorectal cancer from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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36. LPACs were not detected transitioning from non-LPACs. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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37. Validation of EID3 expression in LPACs. from Cancer Stem-like Properties in Colorectal Cancer Cells with Low Proteasome Activity

Author

Munakata, Koji, primary, Uemura, Mamoru, primary, Tanaka, Shinji, primary, Kawai, Kenji, primary, Kitahara, Tomohiro, primary, Miyo, Masaaki, primary, Kano, Yoshihiro, primary, Nishikawa, Shinpei, primary, Fukusumi, Takahito, primary, Takahashi, Yusuke, primary, Hata, Taishi, primary, Nishimura, Junichi, primary, Takemasa, Ichiro, primary, Mizushima, Tsunekazu, primary, Ikenaga, Masakazu, primary, Kato, Takeshi, primary, Murata, Kohei, primary, Carethers, John M., primary, Yamamoto, Hirofumi, primary, Doki, Yuichiro, primary, and Mori, Masaki, primary

Published
2023
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39. Clinical development and evaluation of plasma angiogenesis factors from phase II study of FOLFIRI plus ramucirumab with recurrent colorectal cancer refractory to adjuvant chemotherapy with oxaliplatin/fluoropyrimidine (RAINCLOUD): RAINCLOUD-TR.

Author

Hata, Tsuyoshi, primary, Sugimoto, Naotoshi, additional, Ohara, Nobuyoshi, additional, Miyo, Masaaki, additional, Yoshioka, Shinichi, additional, Kagawa, Yoshinori, additional, Naito, Atsushi, additional, Tei, Mitsuyoshi, additional, Tamagawa, Hiroshi, additional, Konishi, Ken, additional, Sawada, Genta, additional, Danno, Katsuki, additional, Shimokawa, Toshio, additional, Satoh, Taroh, additional, Miyoshi, Norikatsu, additional, Takahashi, Hidekazu, additional, Uemura, Mamoru, additional, Murata, Kohei, additional, Doki, Yuichiro, additional, and Eguchi, Hidetoshi, additional

Published
2023
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44. The Author Replies

Author

Miyo, Masaaki, Takemasa, Ichiro, Ishihara, Hiroyuki, Hata, Taishi, Mizushima, Tsunekazu, Ohno, Yuko, Doki, Yuichiro, and Mori, Masaki

Published
2017
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45. Clinical outcomes of neoadjuvant chemotherapy for resectable colorectal liver metastasis with intermediate risk of postoperative recurrence: A multi‐institutional retrospective study.

Author

Noda, Takehiro, Takahashi, Hidekazu, Tei, Mitsuyoshi, Nishida, Naohiro, Hata, Taishi, Takeda, Yutaka, Ohue, Masayuki, Wada, Hiroshi, Mizushima, Tsunekazu, Asaoka, Tadafumi, Uemura, Mamoru, Kobayashi, Shogo, Murata, Kohei, Satoh, Taroh, Doki, Yuichiro, Eguchi, Hidetoshi, Miyo, Masaaki, Sakai, Kenji, Tujie, Masanori, and Ide, Yoshihito

Abstract

Aims: Risk‐scoring systems for colorectal liver metastasis (CRLM) after hepatectomy allow prognoses to be predicted preoperatively. We investigated the clinical outcomes of neoadjuvant chemotherapy for resectable CRLM according to patient risk status, aiming to determine the subgroup of patients who could benefit from neoadjuvant chemotherapy. Methods: In this multi‐institutional retrospective analysis, the preoperative risk score was calculated from six previously reported factors: synchronous metastases, primary lymph node positivity, tumor number, largest tumor diameter, extrahepatic metastasis, and the preoperative carbohydrate antigen 19–9 level. Patients were divided into three groups according to their risk scores: low risk (score = 0), intermediate risk (score 1–10), and high risk (score ≥11). Overall and recurrence‐free survival curves were calculated using the Kaplan–Meier method. After propensity‐score matching in the intermediate‐risk group, we compared clinicopathological features and outcomes. Results: There were 318 cases, from 20 institutions. The preoperative risk score could be calculated in 277 cases. There were 34, 192, and 51 patients in the low‐, intermediate‐, and high‐risk groups, respectively. Intermediate‐risk group patients who received neoadjuvant chemotherapy had significantly better recurrence‐free survival than that of patients without neoadjuvant chemotherapy (P =.0453). After propensity‐score matching in the intermediate‐risk group, the recurrence‐free survival rate was better in patients who received neoadjuvant chemotherapy (P =.0261). But the overall survival rate was not improved after the matching. Conclusion: Neoadjuvant chemotherapy for resectable CRLM might prolong the recurrence‐free survival period for intermediate‐risk patients with preoperative risk scores in the range of 1–10, but the overall survival was not improved by neoadjuvant chemotherapy. [ABSTRACT FROM AUTHOR]

Published
2023
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47. A Case of Mixed Neuroendocrine and Non-Neuroendocrine Neoplasms of the Esophagus with Rapid Progression of Postoperative Metastatic Recurrence Accompanying Trousseau’s Syndrome

Author

Sakano, Yu, primary, Nishikawa, Kazuhiro, additional, Hamakawa, Takuya, additional, Toshiyama, Reishi, additional, Miyo, Masaaki, additional, Takahashi, Yusuke, additional, Miyake, Masakazu, additional, Miyamoto, Atsushi, additional, Kato, Takeshi, additional, Mori, Kiyoshi, additional, and Hirao, Motohiro, additional

Published
2022
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48. DENEB: Development of new criteria for curability after local excision of pathological T1 colorectal cancer using liquid biopsy

Author

Miyo, Masaaki, primary, Kato, Takeshi, additional, Nakamura, Yoshiaki, additional, Taniguchi, Hiroya, additional, Takahashi, Yusuke, additional, Ishii, Masayuki, additional, Okita, Kenji, additional, Ando, Koji, additional, Yukami, Hiroki, additional, Mishima, Saori, additional, Yamazaki, Kentaro, additional, Kotaka, Masahito, additional, Watanabe, Jun, additional, Oba, Koji, additional, Aleshin, Alexey, additional, Billings, Paul R., additional, Rabinowitz, Matthew, additional, Kotani, Daisuke, additional, Oki, Eiji, additional, Takemasa, Ichiro, additional, Mori, Masaki, additional, and Yoshino, Takayuki, additional

Published
2022
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49. Essential updates 2020/2021: Advancing precision medicine for comprehensive rectal cancer treatment.

Author

Takemasa, Ichiro, Hamabe, Atsushi, Miyo, Masaaki, Akizuki, Emi, and Okuya, Koichi

Abstract

In the paradigm shift related to rectal cancer treatment, we have to understand a variety of new emerging topics to provide appropriate treatment for individual patients as precision medicine. However, information on surgery, genomic medicine, and pharmacotherapy is highly specialized and subdivided, creating a barrier to achieving thorough knowledge. In this review, we summarize the perspective for rectal cancer treatment and management from the current standard‐of‐care to the latest findings to help optimize treatment strategy. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Colorectal Surgery in the COVID-19 Pandemic Era

Author

Miyo, Masaaki, primary, Hata, Tsuyoshi, additional, Sekido, Yuki, additional, Ogino, Takayuki, additional, Miyoshi, Norikatsu, additional, Takahashi, Hidekazu, additional, Uemura, Mamoru, additional, Nishimura, Junichi, additional, Ikenaga, Masakazu, additional, Eguchi, Hidetoshi, additional, Doki, Yuichiro, additional, and Mizushima, Tsunekazu, additional

Published
2022
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