Search

Your search keyword '"Miyata, Akiko"' showing total 37 results
Start Over Author "Miyata, Akiko"
37 results on '"Miyata, Akiko"'

1. A Multi-Institutional Study of Older Hearing Aids Beginners—A Prospective Single-Arm Observation on Executive Function and Social Interaction

Author

Uchida, Yasue, Mise, Kazuyo, Suzuki, Daiji, Fukunaga, Yoko, Hakuba, Nobuhiro, Oishi, Naoki, Ogawa, Takaki, Takahashi, Mariko, Takumi, Yutaka, Fujimoto, Shohei, Maeda, Yukihide, Nishizaki, Kazunori, Noda, Teppei, Komune, Noritaka, Matsumoto, Nozomu, Nakagawa, Takashi, Nishita, Yukiko, Otsuka, Rei, Maegawa, Azusa, Kimizuka, Tomomi, Miyata, Akiko, Gonda, Ayako, Ishikawa, Kazuha, Higashino, Yoshie, and Murakami, Shingo

Published
2021
Full Text
View/download PDF

2. Research Letters

Author

Bandi, Ramya, Lathiya, Rini, Lingappa, Lokesh, Konanki, Ramesh, Kimiya, Takahisa, Shinjoh, Masayoshi, Miyata, Akiko, Takahashi, Takao, Shah, Sachin, Kaul, Amita, Shah, Rima, and Maddipoti, Sankeerth

Published
2021
Full Text
View/download PDF

6. A comparative study of the incidence of aseptic meningitis in symptomatic natural mumps patients and monovalent mumps vaccine recipients in Japan

Author

Nagai, Takao, Okafuji, Teruo, Miyazaki, Chiaki, Ito, Yuhei, Kamada, Makoto, Kumagai, Takuji, Yuri, Kenji, Sakiyama, Hiroshi, Miyata, Akiko, Ihara, Toshiaki, Ochiai, Hitoshi, Shimomura, Kunihisa, Suzuki, Eitaro, Torigoe, Sadayoshi, Igarashi, Masahiro, Kase, Tetsuo, Okuno, Yoshinobu, and Nakayama, Tetsuo

Published
2007
Full Text
View/download PDF

7. Effectiveness of four doses of pertussis vaccine during infancy diminished in elementary school age: A test-negative case-control study in Japan

Author

Ohfuji, Satoko, primary, Okada, Kenji, additional, Mouri, Yoko, additional, Mihara, Yuka, additional, Ishii, Shigeki, additional, Miyata, Akiko, additional, Fujino, Motoko, additional, Motomura, Chikako, additional, Ito, Hiroaki, additional, Ohta, Mitsuhiro, additional, Kasahara, Yoshihito, additional, Nakamura, Hideo, additional, Hasui, Masaki, additional, Yoshikawa, Tetsushi, additional, Tanaka, Takaaki, additional, Nakano, Takashi, additional, Koshida, Rie, additional, Araki, Kaoru, additional, Hara, Megumi, additional, and Hirota, Yoshio, additional

Published
2021
Full Text
View/download PDF

8. Efficacy of inactivated trivalent influenza vaccine in alleviating the febrile illness of culture-confirmed influenza in children in the 2000–2001 influenza season

Author

Kamada, Makoto, Nagai, Takao, Kumagai, Takuji, Igarashi, Masahiro, Ihara, Toshiaki, Okafuji, Teruo, Ochiai, Hitoshi, Sakiyama, Hiroshi, Shimomura, Kunihisa, Suzuki, Eitaro, Torigoe, Sadayoshi, Miyazaki, Chiaki, Miyata, Akiko, Yuri, Kenji, Ito, Yuhei, Nakayama, Tetsuo, Kase, Tetsuo, and Okuno, Yoshinobu

Published
2006
Full Text
View/download PDF

9. Research Letters

Author

Bandi, Ramya, primary, Lathiya, Rini, additional, Lingappa, Lokesh, additional, Konanki, Ramesh, additional, Kimiya, Takahisa, additional, Shinjoh, Masayoshi, additional, Miyata, Akiko, additional, Takahashi, Takao, additional, Shah, Sachin, additional, Kaul, Amita, additional, Shah, Rima, additional, and Maddipoti, Sankeerth, additional

Published
2020
Full Text
View/download PDF

13. Novel mutations in SLC30A2 involved in the pathogenesis of transient neonatal zinc deficiency

Author

Itsumura, Naoya, Kibihara, Yoshie, Fukue, Kazuhisa, Miyata, Akiko, Fukushima, Kenji, Tamagawa-Mineoka, Risa, Katoh, Norito, Nishito, Yukina, Ishida, Riko, Narita, Hiroshi, Kodama, Hiroko, and Kambe, Taiho

Abstract

BACKGROUND: Infants are vulnerable to zinc deficiency. Thus, abnormally low breast milk zinc levels cause transient neonatal zinc deficiency (TNZD) in breast-fed infants. TNZD has been considered to be rare because of a paucity of citations in the published literature. However, recent studies of affected mothers identified four missense mutations in the solute carrier family 30 member 2 gene (SLC30A2), which encodes the zinc transporter, ZnT2. METHODS: Genetic analyses of SLC30A2/ZnT2 in three Japanese mothers secreting low-zinc milk (whose infants developed TNZD) were performed. The effects of identified mutations were examined in a cell-based assay. Furthermore, 31 single-nucleotide polymorphisms (SNPs) in SLC30A2/ZnT2 were evaluated for their potential involvement in low-zinc levels in milk. RESULTS: Each mother had a different novel heterozygous mutation in SLC30A2/ZnT2. One mutation reduced splicing efficiency of the SLC30A2/ZnT2 transcript, and all ZnT2 mutants were defective in zinc transport and were unstable in cells. Moreover, four SNPs caused a significant loss of zinc-transport activity, similar to that in disease-causing ZnT2 mutants. CONCLUSION: Our results indicate that many SLC30A2/ZnT2 mutations cause or potentially cause TNZD. Genetic information concerning TNZD pathogenesis is limited, and our results suggest that the TNZD frequency may be higher than previously thought.

Published
2016

14. Subject of teaching practice for school health

Author

Kawasaki, Hiromi, Fujimoto, Hitomi, Yasuda, Rie, Miyata, Akiko, Goto, Miyuki, Ochiai, Sayuri, Aizawa, Mitsue, Morisada, Tomoko, Uotani, Kaori, Aratani, Mitsuko, Yuba, Naoko, Yabe, Yuko, and Yanagida, Yuko

Published
2007

16. Novel mutations in SLC30A2 involved in the pathogenesis of transient neonatal zinc deficiency

Author

20867709, 90303875, Itsumura, Naoya, Kibihara, Yoshie, Fukue, Kazuhisa, Miyata, Akiko, Fukushima, Kenji, Tamagawa-Mineoka, Risa, Katoh, Norito, Nishito, Yukina, Ishida, Riko, Narita, Hiroshi, Kodama, Hiroko, Kambe, Taiho, 20867709, 90303875, Itsumura, Naoya, Kibihara, Yoshie, Fukue, Kazuhisa, Miyata, Akiko, Fukushima, Kenji, Tamagawa-Mineoka, Risa, Katoh, Norito, Nishito, Yukina, Ishida, Riko, Narita, Hiroshi, Kodama, Hiroko, and Kambe, Taiho

Abstract

BACKGROUND: Infants are vulnerable to zinc deficiency. Thus, abnormally low breast milk zinc levels cause transient neonatal zinc deficiency (TNZD) in breast-fed infants. TNZD has been considered to be rare because of a paucity of citations in the published literature. However, recent studies of affected mothers identified four missense mutations in the solute carrier family 30 member 2 gene (SLC30A2), which encodes the zinc transporter, ZnT2. METHODS: Genetic analyses of SLC30A2/ZnT2 in three Japanese mothers secreting low-zinc milk (whose infants developed TNZD) were performed. The effects of identified mutations were examined in a cell-based assay. Furthermore, 31 single-nucleotide polymorphisms (SNPs) in SLC30A2/ZnT2 were evaluated for their potential involvement in low-zinc levels in milk. RESULTS: Each mother had a different novel heterozygous mutation in SLC30A2/ZnT2. One mutation reduced splicing efficiency of the SLC30A2/ZnT2 transcript, and all ZnT2 mutants were defective in zinc transport and were unstable in cells. Moreover, four SNPs caused a significant loss of zinc-transport activity, similar to that in disease-causing ZnT2 mutants. CONCLUSION: Our results indicate that many SLC30A2/ZnT2 mutations cause or potentially cause TNZD. Genetic information concerning TNZD pathogenesis is limited, and our results suggest that the TNZD frequency may be higher than previously thought.

Published
2016

23. Humoral Immune Response to Influenza A(H1N1)pdm2009 in Patients with Natural Infection and in Vaccine Recipients in the 2009 Pandemic

Author

Kumagai, Takuji, primary, Nakayama, Tetsuo, additional, Okuno, Yoshinobu, additional, Kase, Tetsuo, additional, Nishimura, Naoko, additional, Ozaki, Takao, additional, Miyata, Akiko, additional, Suzuki, Eitaro, additional, Okafuji, Teruo, additional, Okafuji, Takao, additional, Ochiai, Hitoshi, additional, Nagata, Nobuo, additional, Tsutsumi, Hiroyuki, additional, Okamatsu, Masatoshi, additional, Sakoda, Yoshihiro, additional, Kida, Hiroshi, additional, and Ihara, Toshiaki, additional

Published
2014
Full Text
View/download PDF

24. Production of inflammatory cytokines in response to diphtheria-pertussis-tetanus (DPT),haemophilus influenzaetype b (Hib), and 7-valent pneumococcal (PCV7) vaccines

Author

Kashiwagi, Yasuyo, primary, Miyata, Akiko, additional, Kumagai, Takuji, additional, Maehara, Kouji, additional, Suzuki, Eitarou, additional, Nagai, Takao, additional, Ozaki, Takao, additional, Nishimura, Naoko, additional, Okada, Kenji, additional, Kawashima, Hisashi, additional, and Nakayama, Tetsuo, additional

Published
2013
Full Text
View/download PDF

29. Molecular epidemiology of mumps virus in Japan and proposal of two new genotypes

Author

Inou, Yoko, primary, Nakayama, Tetsuo, additional, Yoshida, Naoko, additional, Uejima, Hajime, additional, Yuri, Kenji, additional, Kamada, Makoto, additional, Kumagai, Takuji, additional, Sakiyama, Hiroshi, additional, Miyata, Akiko, additional, Ochiai, Hitoshi, additional, Ihara, Toshiaki, additional, Okafuji, Teruo, additional, Okafuji, Takao, additional, Nagai, Takao, additional, Suzuki, Eitaro, additional, Shimomura, Kunihisa, additional, Ito, Yuhei, additional, and Miyazaki, Chiaki, additional

Published
2004
Full Text
View/download PDF

35. Production of inflammatory cytokines in response to diphtheria-pertussis-tetanus (DPT), haemophilus influenzaetype b (Hib), and 7-valent pneumococcal (PCV7) vaccines

Author

Kashiwagi, Yasuyo, Miyata, Akiko, Kumagai, Takuji, Maehara, Kouji, Suzuki, Eitarou, Nagai, Takao, Ozaki, Takao, Nishimura, Naoko, Okada, Kenji, Kawashima, Hisashi, and Nakayama, Tetsuo

Abstract

Haemophilus influenzaetype b (Hib) and 7-valent pneumococcal (PCV7) vaccines both became recommended in Japan in 2010. In this study, cytokine production was investigated in peripheral blood mononuclear cells (PBMCs) cultures stimulated with diphtheria and tetanus toxoids combined with acellular pertussis vaccine (DPT), Hib, and PCV7 separately or concurrent different combinations, all as final off-the-shelf vaccines without the individual vaccine components as controls. Higher IL-1β levels were produced when cultures were stimulated with PCV than with DPT or Hib, and the concurrent stimulation including PCV7 enhanced the production of IL-1β. Although Hib induced higher levels of IL-6, no significant difference was observed in IL-6 production with the concurrent stimulation. The concurrent stimulation with Hib/PCV7 and DPT/Hib/PCV7 produced higher levels of TNF-α and human G-CSF. Cytokine profiles were examined in serum samples obtained from 61 vaccine recipients with febrile reactions and 18 recipients without febrile illness within 24 h of vaccination. No significant difference was observed in cytokine levels of IL-1β, IL-4, IL-6, IL-10, IL-12, IFN-γ, MIP-1, TNF-α, and prostaglandin E2 (PGE2) in sera between the two groups. However, significantly higher levels of human G-CSF were observed in recipients with febrile illness than in those without febrile reactions. Further investigations of the significance of elevated serum G-CSF levels are required in vaccine recipients with febrile illness.

Published
2014
Full Text
View/download PDF

36. Pertussis Epidemic in Lower-Grade Schoolchildren Without Preschool Vaccination Boosters.

Author

Kimiya T, Shinjoh M, Miyata A, and Takahashi T

Subjects
Child, Child, Preschool, Humans, Immunization, Secondary, Pertussis Vaccine, Schools, Vaccination, Epidemics, Whooping Cough epidemiology, Whooping Cough prevention & control
Abstract

We investigated the characteristics of patients with pertussis who did not receive preschool vaccination boosters. Fifteen patients with laboratory-confirmed pertussis and 29 pertussis-negative patients were compared. All pertussis-positive patients, but only 17% of pertussis-negative patients, were elementary school age and older. There is a need to study the utility of routine preschool pertussis vaccine booster in Japan.

Published
2021

37. Staphylococcal enterotoxin B enhances a flare-up reaction of murine contact hypersensitivity through up-regulation of interferon-gamma.

Author

Miyata A, Natsuaki M, and Yamanishi K

Subjects
Animals, Cell Division immunology, Chronic Disease, Dermatitis, Contact metabolism, Dinitrofluorobenzene toxicity, Disease Models, Animal, Ear, External, Edema immunology, Edema metabolism, Edema microbiology, Female, Interleukin-5 metabolism, Lymph Nodes cytology, Mice, Mice, Inbred BALB C, Staphylococcal Skin Infections metabolism, Up-Regulation immunology, Dermatitis, Contact immunology, Dermatitis, Contact microbiology, Enterotoxins toxicity, Interferon-gamma metabolism, Staphylococcal Skin Infections immunology
Abstract

Background: We often see aggravation of eczematous skin lesions associated with bacterial infection, but the mechanism of this phenomenon is unclear. Staphylococcus aureus is known to colonize on the eczematous lesion and produce some exotoxins, which act as bacterial superantigens., Objectives: To investigate the potential role of superantigens in chronic dermatitis, we investigated the effect of staphylococcal enterotoxin B (SEB) on the skin reaction, the proliferative response and the cytokine production of local lymph node cells in the mouse model of contact hypersensitivity reaction., Methods: Sensitized BALB/c mice were repeatedly challenged with dinitrofluorobenzene (DNFB), and intravenously injected with SEB and dinitrobenzne sulfonic acid sodium salt (DNBS). The ear swelling response was measured after DNBS injection. Cervical lymph node cells of those mice were cultured with DNBS in vitro. Their proliferative responses and the production of cytokines were assessed., Results: SEB markedly enhanced the flare-up reaction of ear swelling induced by DNBS, the proliferative response of lymph node cells and the production of IFN-gamma. In contrast, the production of IL-5 was decreased., Conclusions: The present study may provide some clues for elucidating the mechanism involved in the exacerbation of dermatitis associated with staphylococcal infection.

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results