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163 results on '"Miyasaka, Yuhei"'

18. Carbon‐ion radiotherapy for oligometastatic liver disease: A national multicentric study by the Japan Carbon‐Ion Radiation Oncology Study Group (J‐CROS)

Author

Shiba, Shintaro, primary, Wakatsuki, Masaru, additional, Toyama, Shingo, additional, Terashima, Kazuki, additional, Uchida, Hirofumi, additional, Katoh, Hiroyuki, additional, Shibuya, Kei, additional, Okazaki, Shohei, additional, Miyasaka, Yuhei, additional, Ohno, Tatsuya, additional, and Tsuji, Hiroshi, additional

Published
2023
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21. Comprehensive analysis of Japanese nationwide cohort data of particle beam therapy for pulmonary, liver and lymph node oligometastases: particle beam therapy versus high-precision X-ray radiotherapy

Author

Aibe, Norihiro, primary, Ogino, Hiroyuki, additional, Wakatsuki, Masaru, additional, Fujikawa, Kei, additional, Teramukai, Satoshi, additional, Fukumitsu, Nobuyoshi, additional, Shiba, Shintaro, additional, Yamamoto, Naoyoshi, additional, Nomoto, Akihiro, additional, Ono, Takashi, additional, Oguri, Masanosuke, additional, Yamaguchi, Hisashi, additional, Numajiri, Haruko, additional, Shibuya, Kei, additional, Okazaki, Shohei, additional, Miyasaka, Yuhei, additional, Okonogi, Noriyuki, additional, Murata, Kazutoshi, additional, Tatebe, Hitoshi, additional, Motegi, Atsushi, additional, Okimoto, Tomoaki, additional, Yoshino, Takayuki, additional, Mandai, Masaki, additional, Katoh, Norio, additional, Tsuji, Hiroshi, additional, and Sakurai, Hideyuki, additional

Published
2023
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25. Pelvic insufficiency fractures following carbon-ion radiotherapy for uterine carcinomas

Author

Miyasaka, Yuhei, Okonogi, Noriyuki, Fukahori, Mai, Furuichi, Wataru, Wakatsuki, Masaru, Kato, Shingo, Ohno, Tatsuya, Nakano, Takashi, Tsuji, Hiroshi, Yuhei, Miyasaka, Noriyuki, Okonogi, Mai, Fukahori, Wataru, Furuichi, Masaru, Wakatsuki, Shingo, Kato, Tatsuya, Ohno, Takashi, Nakano, and Hiroshi, Tsuji

Abstract

Background and purpose: There is growing evidence on the role of carbon-ion radiotherapy (C-ion RT) for gynaecological tumours. Pelvic insufficiency fracture (PIF) decreases the quality of life after photon beam radiotherapy (RT). However, there is little information on PIF after C-ion RT. This study retrospectively assessed incidence of PIF after C-ion RT for uterine carcinomas (UCs) and the associations of clinical and dosimetric parameters with PIF incidence. Material and methods: We performed a pooled analysis of 102 patients with UCs who underwent definitive C-ion RT alone and were followed up for >6 months without any additional RT in the pelvic region. PIF occurrence was surveyed using magnetic resonance imaging and/or computed tomography. Associations of clinical and dosimetric parameters with PIF incidence were analysed. Results: The 2- and 5-year actuarial incidences of ≥grade 1 PIF in all pelvic regions were 22.3% and 42.4%, respectively. The most frequent site of involvement was the sacrum. Log-rank tests showed that higher volumes receiving >10 Gy (relative biological effectiveness) (V10), V20, V30, and V40, body mass index (BMI) under 18.5, and current smoking were associated with increased incidence of ≥grade 1 PIF in the sacrum. Conclusions: We clarified the actuarial incidence of PIF after C-ion RT for UCs. Higher V10, V20, V30, V40, D50%, Dmean, current smoking, BMI

Published
2020

26. Comparative study of RARP and carbon ion radiotherapy sexual functional changes for prostate cancer using the propensity score matching method.

Author

Miyazawa, Yoshiyuki, primary, Oka, Daisuke, additional, Koike, Hidekazu, additional, Kawamura, Hidemasa, additional, Miyasaka, Yuhei, additional, Syuto, Takahiro, additional, Arai, Seiji, additional, Sekine, Yoshitaka, additional, Matsui, Hiroshi, additional, Ohno, Tatsuya, additional, and Suzuki, Kazuhiro, additional

Published
2022
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30. A Phase 1/2 Study of Carbon Ion Radiotherapy with Concurrent Chemotherapy for Locally Advanced Uterine Cervical Squamous Cell Carcinoma (Protocol 1302)

Author

Okonogi, Noriyuki, Wakatsuki, Masaru, Kato, Shingo, Karasawa, Kumiko, Miyasaka, Yuhei, Murata, Hiroto, Nakano, Takashi, Kamada, Tadashi, and Shozu, Makio

Subjects
stomatognathic diseases
Abstract

This study evaluated the safety and efficacy of carbon-ion radiotherapy (C-ion RT) with concurrent chemotherapy (chemo-C-ion RT) for locally advanced uterine cervical squamous cell carcinoma in a phase 1/2 clinical trial.

Published
2019

32. Efficacy and Safety of Carbon-Ion Radiotherapy for Stage I Non-Small Cell Lung Cancer with Coexisting Interstitial Lung Disease

Author

Okano, Naoko, primary, Kubo, Nobuteru, additional, Yamaguchi, Koichi, additional, Kouno, Shunichi, additional, Miyasaka, Yuhei, additional, Mizukami, Tatsuji, additional, Shirai, Katsuyuki, additional, Saitoh, Jun-ichi, additional, Ebara, Takeshi, additional, Kawamura, Hidemasa, additional, Maeno, Toshitaka, additional, and Ohno, Tatsuya, additional

Published
2021
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35. Kinetics of Prostate-Specific Antigen after Carbon Ion Radiotherapy for Prostate Cancer

Author

Dewi Maulany Darwis , Narisa, Oike, Takahiro, Kawamura, Hidemasa, Kawahara, Masahiro, Kubo, Nobuteru, Sato, Hiro, Miyasaka, Yuhei, Katoh, Hiroyuki, Ishikawa, Hitoshi, Matsui, Hiroshi, Miyazawa, Yoshiyuki, Ito, Kazuto, Suzuki, Kazuhiro, Gondhowiardjo, Soehartati, Nakano, Takashi, and Ohno, Tatsuya

Subjects
urologic and male genital diseases
Abstract

This study aimed to first elucidate prostate-specific antigen (PSA) kinetics in prostate cancer patients treated with carbon ion radiotherapy (CIRT). From 2010 to 2015, 131 patients with prostate adenocarcinoma treated with CIRT (57.6 Gy relative biological effectiveness (RBE) in 16 fractions) alone were recruited. PSA was measured at 1, 2, 3, 6, 9, 12, 15, 18, 21, 24, 30, 36, 42, 48, 54, and 60 months post-CIRT. PSA bounce was defined as PSA increase over a cutoff followed by spontaneous decrease to or below the pre-bounce nadir. PSA failure was determined using the Phoenix criteria (nadir + 2.0 ng/mL). As a result, non-failure-associated temporary increase in PSA exhibited two distinct patterns, namely a classical bounce and a surge at one month. PSA bounce of ≥0.2 ng/mL was observed in 55.7% of the patients. Bounce amplitude was

Published
2020

36. Rectal dose-sparing effect with bioabsorbable spacer placement in carbon ion radiotherapy for sacral chordoma: dosimetric comparison of a simulation study

Author

Shiba, Shintaro, primary, Okamoto, Masahiko, additional, Tashiro, Mutsumi, additional, Ogawa, Hiroomi, additional, Osone, Katsuya, additional, Yanagawa, Takashi, additional, Kohama, Isaku, additional, Okazaki, Shohei, additional, Miyasaka, Yuhei, additional, Osu, Naoto, additional, Chikuda, Hirotaka, additional, Saeki, Hiroshi, additional, and Ohno, Tatsuya, additional

Published
2021
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39. Comparison of Oncologic Outcomes between Carbon Ion Radiotherapy and Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer

Author

Miyasaka, Yuhei, primary, Komatsu, Shuichiro, additional, Abe, Takanori, additional, Kubo, Nobuteru, additional, Okano, Naoko, additional, Shibuya, Kei, additional, Shirai, Katsuyuki, additional, Kawamura, Hidemasa, additional, Saitoh, Jun-ichi, additional, Ebara, Takeshi, additional, and Ohno, Tatsuya, additional

Published
2021
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42. Evaluation of Carbon Ion Radiation-Induced Trismus in Head and Neck Tumors Using Dose-Volume Histograms

Author

Musha, Atsushi, primary, Shimada, Hirofumi, additional, Kubo, Nobuteru, additional, Kawamura, Hidemasa, additional, Okano, Naoko, additional, Miyasaka, Yuhei, additional, Sato, Hiro, additional, Shirai, Katsuyuki, additional, Saitoh, Jun-ichi, additional, Yokoo, Satoshi, additional, Chikamatsu, Kazuaki, additional, and Ohno, Tatsuya, additional

Published
2020
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43. Carbon ion radiotherapy for prostate cancer with bladder invasion

Author

Miyasaka, Yuhei, primary, Kawamura, Hidemasa, additional, Sato, Hiro, additional, Kubo, Nobuteru, additional, Mizukami, Tatsuji, additional, Matsui, Hiroshi, additional, Miyazawa, Yoshiyuki, additional, Ito, Kazuto, additional, Nakano, Takashi, additional, Suzuki, Kazuhiro, additional, and Ohno, Tatsuya, additional

Published
2020
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44. Skin Dose Reduction by Layer-Stacking Irradiation in Carbon Ion Radiotherapy for Parotid Tumors

Author

Kubo, Nobuteru, primary, Kubota, Yoshiki, additional, Oike, Takahiro, additional, Kawamura, Hidemasa, additional, Sakai, Makoto, additional, Imamura, Ayaka, additional, Komatsu, Shuichiro, additional, Miyasaka, Yuhei, additional, Sato, Hiro, additional, Musha, Atsushi, additional, Okano, Naoko, additional, Shirai, Katsuyuki, additional, Saitoh, Jun-ichi, additional, Chikamatsu, Kazuaki, additional, and Ohno, Tatsuya, additional

Published
2020
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45. Impact of Inter-fractional Anatomical Changes on Dose Distributions in Passive Carbon-Ion Radiotherapy for Prostate Cancer: Comparison of Vertical and Horizontal Fields

Author

Yokoyama, Ayaka, primary, Kubota, Yoshiki, additional, Kawamura, Hidemasa, additional, Miyasaka, Yuhei, additional, Kubo, Nobuteru, additional, Sato, Hiro, additional, Abe, Satoshi, additional, Tsuda, Kazuhisa, additional, Sutou, Takayuki, additional, Ohno, Tatsuya, additional, and Nakano, Takashi, additional

Published
2020
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47. Kinetics of Prostate-Specific Antigen after Carbon Ion Radiotherapy for Prostate Cancer

Author

Darwis, Narisa Dewi Maulany, primary, Oike, Takahiro, additional, Kawamura, Hidemasa, additional, Kawahara, Masahiro, additional, Kubo, Nobuteru, additional, Sato, Hiro, additional, Miyasaka, Yuhei, additional, Katoh, Hiroyuki, additional, Ishikawa, Hitoshi, additional, Matsui, Hiroshi, additional, Miyazawa, Yoshiyuki, additional, Ito, Kazuto, additional, Suzuki, Kazuhiro, additional, Gondhowiardjo, Soehartati, additional, Nakano, Takashi, additional, and Ohno, Tatsuya, additional

Published
2020
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48. Treatment outcomes of patients with adenocarcinoma of the uterine cervix after definitive radiotherapy and the prognostic impact of tumor-infiltrating CD8+ lymphocytes in pre-treatment biopsy specimens: a multi-institutional retrospective study

Author

Miyasaka, Yuhei, primary, Yoshimoto, Yuya, primary, Murata, Kazutoshi, primary, Noda, Shin-ei, primary, Ando, Ken, primary, Ebara, Takeshi, primary, Okonogi, Noriyuki, primary, Kaminuma, Takuya, primary, Yamada, Seiji, primary, Ikota, Hayato, primary, Yokoo, Hideaki, primary, Ohno, Tatsuya, primary, and Nakano, Takashi, primary

Published
2020
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49. Cost‐effectiveness of carbon‐ion radiotherapy versus stereotactic body radiotherapy for non‐small‐cell lung cancer.

Author

Okazaki, Shohei, Shibuya, Kei, Takura, Tomoyuki, Miyasaka, Yuhei, Kawamura, Hidemasa, and Ohno, Tatsuya

Abstract

Carbon‐ion radiotherapy (CIRT) for clinical stage I non‐small‐cell lung cancer (NSCLC) is used as an advanced medical treatment regimen in Japan. Carbon‐ion radiotherapy reportedly aids in achieving excellent treatment outcomes, despite its high medical cost. We aimed to compare CIRT with stereotactic body radiotherapy (SBRT) in terms of cost‐effectiveness for treating clinical stage I NSCLC. Data of patients with clinical stage I NSCLC treated with CIRT or SBRT at Gunma University between 2010 and 2015 were analyzed. The CIRT and SBRT groups included 62 and 27 patients, respectively. After propensity‐score matching, both groups comprised 15 patients. Life year (LY) was used as an indicator of outcome. The CIRT technical fee was 3 140 000 JPY. There was no technical fee for the second CIRT carried out on the same organ within 2 years. The incremental cost‐effectiveness ratio (ICER) was calculated by dividing the incremental cost by the incremental LY for 5 years after treatment. Sensitivity analysis was applied to evaluate the impact of LY or costs of each group on ICER. The ICERs were 7 491 017 JPY/LY and 3 708 330 JPY/LY for all patients and matched patients, respectively. Hospitalization and examination costs were significantly higher in the CIRT group, and the impact of the CIRT technical costs was smaller than other costs and LY. Carbon‐ion radiotherapy is a cost‐effective treatment approach. However, our findings suggest that reducing excessive costs by considering the validity and necessity of examinations and hospitalizations would make CIRT a more cost‐effective approach. [ABSTRACT FROM AUTHOR]

Published
2022
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50. Additional file 8: of Dose constraints in the rectum and bladder following carbon-ion radiotherapy for uterus carcinoma: a retrospective pooled analysis

Author

Okonogi, Noriyuki, Fukahori, Mai, Wakatsuki, Masaru, Ohkubo, Yu, Kato, Shingo, Miyasaka, Yuhei, Tsuji, Hiroshi, Nakano, Takashi, and Kamada, Tadashi

Abstract

Table S3. Correlation between dose-volume histogram parameters and late morbidities of the rectum in the 24 fractions group. This table summarizes the doseâ volume histogram parameters from V10 to V60, D5cc, D2cc, and Dmax according to the grading of rectal morbidity in the 24 fractions group. (DOCX 16 kb)

Published
2018
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