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20 results on '"Miyakawa, Teppei"'

3. Radiological Cutoff Values for Diagnosis of Lymph Node Metastasis in Colorectal Cancer With Multilevel Analysis

Author

TODATE, YUKITOSHI, primary, TAKADA, TOSHIHIKO, additional, HONDA, MICHITAKA, additional, MIYAKAWA, TEPPEI, additional, YAMAMOTO, RYUYA, additional, TOSHIYAMA, SATOSHI, additional, NAKAO, EIICHI, additional, MASHIKO, RYUTARO, additional, KAKINUMA, HIROHITO, additional, KAWAMURA, HIDETAKA, additional, YAMAGUCHI, HISASHI, additional, TAKAGAWA, YOSHIAKI, additional, and KONO, KOJI, additional

Published
2024
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11. Impact of histological subtype on prognosis in stage IV colorectal cancer: A population-based cohort study

Author

Miyakawa, Teppei, primary, Kawamura, Hidetaka, additional, Honda, Michitaka, additional, Takano, Yoshinao, additional, Kinuta, Shunji, additional, Kamiga, Takahiro, additional, Yamazaki, Shigeru, additional, Muto, Atsushi, additional, Shiraso, Satoru, additional, Yamashita, Naoyuki, additional, Iwao, Toshiyasu, additional, Kono, Koji, additional, and Konno, Shinichi, additional

Published
2022
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19. [Neoadjuvant Chemoradiotherapy for Locally Advanced Carcinoma Associated with Anal Fistula].

Author

Miyakawa T, Iida S, Igaki T, Shiobara H, Matsumoto R, Mitachi K, Ohata Y, Saito K, Miura T, Irie T, and Yamazaki S

Subjects
Anus Neoplasms complications, Anus Neoplasms pathology, Humans, Male, Middle Aged, Rectal Fistula surgery, Recurrence, Adenocarcinoma therapy, Anus Neoplasms therapy, Chemoradiotherapy, Neoadjuvant Therapy, Rectal Fistula etiology
Abstract

The patient was a 59-year-old man. He was admitted to our hospital because of increasing anal pain with induration of the perianal region. There were large secondary orifices with mucous discharge on the left side of the perineal resion and buttock. We diagnosed adenocarcinoma on analysis of a biopsy specimen from induration of the perianal region. Pelvic CT and MRI showed that the tumor spreaded within the pelvis, with invasion of the prostate and sacrum. We performed neoadjuvant chemoradiotherapy preoperatively. After chemoradiotherapy, the tumor reduced in size greatly. We performed abdominoperineal resection and massive resection of skin of the perianal region. The defect of the pelvic floor and perianal skin was repaired using skin flap. The surgical margin was tumor free. Neoadjuvant chemoradiotherapy was considered effective for locally advanced carcinoma associated with anal fistula.

Published
2017

20. [Malignant Pleural Mesothelioma with Excessive Inflammation and High Level of Interleukin 6 - A Case Report].

Author

Miura T, Iida S, Igaki T, Shiobara H, Matsumoto R, Mitachi K, Miyakawa T, Ohata Y, Saitou K, Irie T, and Yamazaki S

Subjects
Antineoplastic Combined Chemotherapy Protocols therapeutic use, Cisplatin administration & dosage, Combined Modality Therapy, Fatal Outcome, Female, Humans, Mesothelioma, Malignant, Pemetrexed administration & dosage, Pleural Neoplasms chemistry, Pleural Neoplasms drug therapy, Pleural Neoplasms surgery, Young Adult, Interleukin-6 blood, Lung Neoplasms chemistry, Lung Neoplasms complications, Lung Neoplasms drug therapy, Lung Neoplasms surgery, Mesothelioma chemistry, Mesothelioma complications, Mesothelioma drug therapy, Mesothelioma surgery, Pleural Neoplasms pathology, Pleurisy etiology
Abstract

Malignant mesothelioma is a rare aggressive solid tumor that is invariably incurable. A 23-year-old female patient with ascites, anemia, and high levels of ferritin and CRP was diagnosed with pleural mesothelioma by exploratory laparotomy. She remained asymptomatic, but 7 years later, she developed intractable diarrhea and fever. Systematic chemotherapy with both cisplatin and pemetrexed was administered. However, the treatment was discontinued due to side effects, after which time the diarrhea, ascites, and fever became progressively more severe. Hepatomegaly and hepatic siderosis also developed. At the same time, the patient's serum interleukin 6(IL-6)levels were abnormally high. Although there was a temporary symptomatic improvement after intraperitoneal injection of cisplatin, the intractable mesothelioma-associated symptoms returned a few days later. The patient died of liver failure 1 week later. The poor prognosis in this case was due to symptoms associated with the high IL-6 level. There are limited medically proven treatments, and it is important to develop new treatments. Therefore, "anti-IL-6 therapy" may have to be tested as a potential treatment for symptoms associated with high IL-6 levels.

Published
2016

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