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3. Low-density lipoprotein particle profiles compared with standard lipids measurements in the association with asymptomatic intracranial artery stenosis

Author

Vu, Thien, Yano, Yuichiro, Pham, Huy Kien Tai, Mondal, Rajib, Ohashi, Mizuki, Kitaoka, Kaori, Moniruzzaman, Mohammad, Torii, Sayuki, Shiino, Akihiko, Tsuji, Atsushi, Hisamatsu, Takashi, Okamura, Tomonori, Kondo, Keiko, Kadota, Aya, Watanabe, Yoshiyuki, Nozaki, Kazuhiko, Ueshima, Hirotsugu, and Miura, Katsuyuki

Published
2024
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5. Including measures of chronic kidney disease to improve cardiovascular risk prediction by SCORE2 and SCORE2-OP.

Author

Matsushita, Kunihiro, Kaptoge, Stephen, Hageman, Steven, Sang, Yingying, Ballew, Shoshana, Grams, Morgan, Surapaneni, Aditya, Sun, Luanluan, Arnlov, Johan, Bozic, Milica, Brenner, Hermann, Brunskill, Nigel, Chang, Alex, Chinnadurai, Rajkumar, Cirillo, Massimo, Correa, Adolfo, Ebert, Natalie, Eckardt, Kai-Uwe, Gansevoort, Ron, Gutierrez, Orlando, Hadaegh, Farzad, He, Jiang, Hwang, Shih-Jen, Jafar, Tazeen, Jassal, Simerjot, Kayama, Takamasa, Kovesdy, Csaba, Landman, Gijs, Levey, Andrew, Lloyd-Jones, Donald, Major, Rupert, Miura, Katsuyuki, Muntner, Paul, Nadkarni, Girish, Nowak, Christoph, Ohkubo, Takayoshi, Pena, Michelle, Polkinghorne, Kevan, Sairenchi, Toshimi, Schaeffner, Elke, Schneider, Markus, Shalev, Varda, Shlipak, Michael, Solbu, Marit, Stempniewicz, Nikita, Tollitt, James, Valdivielso, José, van der Leeuw, Joep, Wang, Angela, Wen, Chi-Pang, Woodward, Mark, Yamagishi, Kazumasa, Yatsuya, Hiroshi, Zhang, Luxia, Dorresteijn, Jannick, Di Angelantonio, Emanuele, Visseren, Frank, Pennells, Lisa, and Coresh, Josef

Subjects
Cardiovascular disease, Chronic kidney disease, Meta-analysis, Risk prediction, Humans, Aged, Aged, 80 and over, Cardiovascular Diseases, Risk Factors, Creatinine, Renal Insufficiency, Chronic, Albuminuria, Glomerular Filtration Rate, Heart Disease Risk Factors
Abstract

AIMS: The 2021 European Society of Cardiology (ESC) guideline on cardiovascular disease (CVD) prevention categorizes moderate and severe chronic kidney disease (CKD) as high and very-high CVD risk status regardless of other factors like age and does not include estimated glomerular filtration rate (eGFR) and albuminuria in its algorithms, systemic coronary risk estimation 2 (SCORE2) and systemic coronary risk estimation 2 in older persons (SCORE2-OP), to predict CVD risk. We developed and validated an Add-on to incorporate CKD measures into these algorithms, using a validated approach. METHODS: In 3,054 840 participants from 34 datasets, we developed three Add-ons [eGFR only, eGFR + urinary albumin-to-creatinine ratio (ACR) (the primary Add-on), and eGFR + dipstick proteinuria] for SCORE2 and SCORE2-OP. We validated C-statistics and net reclassification improvement (NRI), accounting for competing risk of non-CVD death, in 5,997 719 participants from 34 different datasets. RESULTS: In the target population of SCORE2 and SCORE2-OP without diabetes, the CKD Add-on (eGFR only) and CKD Add-on (eGFR + ACR) improved C-statistic by 0.006 (95%CI 0.004-0.008) and 0.016 (0.010-0.023), respectively, for SCORE2 and 0.012 (0.009-0.015) and 0.024 (0.014-0.035), respectively, for SCORE2-OP. Similar results were seen when we included individuals with diabetes and tested the CKD Add-on (eGFR + dipstick). In 57 485 European participants with CKD, SCORE2 or SCORE2-OP with a CKD Add-on showed a significant NRI [e.g. 0.100 (0.062-0.138) for SCORE2] compared to the qualitative approach in the ESC guideline. CONCLUSION: Our Add-ons with CKD measures improved CVD risk prediction beyond SCORE2 and SCORE2-OP. This approach will help clinicians and patients with CKD refine risk prediction and further personalize preventive therapies for CVD.

Published
2023

6. Prologue: Special Spotlight Issue on Japan

Author

Yano, Yuichiro, Nishiyama, Akira, Ishimitsu, Toshihiko, Kashihara, Naoki, Rakugi, Hiromi, Tamura, Kouichi, Itoh, Hiroshi, Tsuchihashi, Takuya, Sakima, Atsushi, Arima, Hisatomi, Matayoshi, Tetsutaro, Imai, Yutaka, Miura, Katsuyuki, Hisamatsu, Takashi, Asayama, Kei, Ohkubo, Takayoshi, Node, Kouihci, and Kario, Kazuomi

Published
2024
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8. Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Author

Sakashita, Takuya, Nakamura, Yasuyuki, Sutoh, Yoichi, Shimizu, Atsushi, Hachiya, Tsuyoshi, Otsuka-Yamasaki, Yayoi, Takashima, Naoyuki, Kadota, Aya, Miura, Katsuyuki, Kita, Yoshikuni, Ikezaki, Hiroaki, Otonari, Jun, Tanaka, Keitaro, Shimanoe, Chisato, Koyama, Teruhide, Watanabe, Isao, Suzuki, Sadao, Nakagawa-Senda, Hiroko, Hishida, Asahi, Tamura, Takashi, Kato, Yasufumi, Okada, Rieko, Kuriki, Kiyonori, Katsuura-Kamano, Sakurako, Watanabe, Takeshi, Tanoue, Shiroh, Koriyama, Chihaya, Oze, Isao, Koyanagi, Yuriko N., Nakamura, Yohko, Kusakabe, Miho, Nakatochi, Masahiro, Momozawa, Yukihide, Wakai, Kenji, and Matsuo, Keitaro

Published
2023
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13. Coronary Artery Calcium Assessed Years Before Was Positively Associated With Subtle White Matter Injury of the Brain in Asymptomatic Middle-Aged Men: The Framingham Heart Study

Author

Suzuki, Harumitsu, Davis-Plourde, Kendra, Beiser, Alexa, Kunimura, Ayako, Miura, Katsuyuki, DeCarli, Charles, Maillard, Pauline, Mitchell, Gary F, Vasan, Ramachandran S, Seshadri, Sudha, and Fujiyoshi, Akira

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Cardiovascular, Neurosciences, Prevention, Heart Disease - Coronary Heart Disease, Brain Disorders, Aging, Biomedical Imaging, Clinical Research, Heart Disease, Neurological, Adult, Age Factors, Asymptomatic Diseases, Coronary Angiography, Coronary Artery Disease, Diffusion Tensor Imaging, Female, Humans, Leukoencephalopathies, Male, Middle Aged, Multidetector Computed Tomography, Predictive Value of Tests, Prognosis, Risk Assessment, Risk Factors, Sex Factors, Time Factors, Vascular Calcification, atherosclerosis, coronary artery calcium, diffusion tensor imaging, pulse wave velocity, white matter, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

BackgroundUsing magnetic resonance diffusion tensor imaging, we previously showed a cross-sectional association between carotid-femoral pulse wave velocity, a measure of aortic stiffness, and subtle white matter injury in clinically asymptomatic middle-age adults. While coronary artery calcium (CAC) is a robust measure of atherosclerosis, and a predictor of stroke and dementia, whether it predicts diffusion tensor imaging-based subtle white matter injury in the brain remains unknown.MethodsIn FHS (Framingham Heart Study), an observational study, third-generation participants were assessed for CAC (2002-2005) and brain magnetic resonance imaging (2009-2014). Outcomes were diffusion tensor imaging-based measures; free water, fractional anisotropy, and peak width of mean diffusivity. After excluding the participants with neurological conditions and missing covariates, we categorized participants into 3 groups according to CAC score (0, 0 < to 100, and >100) and calculated a linear trend across the CAC groups. In secondary analyses treating CAC score as continuous, we computed slope of the outcomes per 20 to 80th percentiles higher log-transformed CAC score using linear regression.ResultsIn a total of 1052 individuals analyzed (mean age 45.4 years, 45.4% women), 71.6%, 22.4%, and 6.0% had CAC score of 0, 0 < to 100, and >100, respectively. We observed a significant linear trend of fractional anisotropy, but not other measures, across the CAC groups after multivariable adjustment. In the secondary analyses, CAC was associated with lower fractional anisotropy in men but not in women.ConclusionsCAC may be a promising tool to predict prevalent subtle white matter injury of the brain in asymptomatic middle-aged men.

Published
2021

16. Circulating plasma phospholipid fatty acid levels as a biomarker of habitual dietary fat intake: The INTERMAP/INTERLIPID Study

Author

Miyagawa, Naoko, Sekikawa, Akira, Miura, Katsuyuki, Evans, Rhobert W., Okuda, Nagako, Fujiyoshi, Akira, Yoshita, Katsushi, Chan, Queenie, Okami, Yukiko, Kadota, Aya, Willcox, Bradley, Masaki, Kamal, Rodriguez, Beatriz, Sakata, Kiyomi, Nakagawa, Hideaki, Saitoh, Shigeyuki, Okayama, Akira, Kuller, Lewis H., Elliott, Paul, Stamler, Jeremiah, and Ueshima, Hirotsugu

Published
2023
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17. A genome-wide association study on adherence to low-carbohydrate diets in Japanese

Author

Nakamura, Yasuyuki, Tamura, Takashi, Narita, Akira, Shimizu, Atsushi, Sutoh, Yoichi, Takashima, Naoyuki, Matsui, Kenji, Miyagawa, Naoko, Kadota, Aya, Miura, Katsuyuki, Otonari, Jun, Ikezaki, Hiroaki, Hishida, Asahi, Nagayoshi, Mako, Okada, Rieko, Kubo, Yoko, Tanaka, Keitaro, Shimanoe, Chisato, Ibusuki, Rie, Nishimoto, Daisaku, Oze, Isao, Ito, Hidemi, Ozaki, Etsuko, Matsui, Daisuke, Mikami, Haruo, Kusakabe, Miho, Suzuki, Sadao, Watanabe, Miki, Arisawa, Kokichi, Katsuura-Kamano, Sakurako, Kuriki, Kiyonori, Nakatochi, Masahiro, Momozawa, Yukihide, Kubo, Michiaki, Takeuchi, Kenji, and Wakai, Kenji

Published
2022
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20. The association of reproductive history with hypertension and obesity according to menopausal status: the J-MICC Study

Author

Ohashi, Mizuki, Miura, Katsuyuki, Takashima, Naoyuki, Kadota, Aya, Saito, Yoshino, Tsuji, Shunichiro, Murakami, Takashi, Kadomatsu, Yuka, Nagayoshi, Mako, Hara, Megumi, Tanaka, Keitaro, Tamura, Takashi, Hishida, Asahi, Takezaki, Toshiro, Shimoshikiryo, Ippei, Ozaki, Etsuko, Watanabe, Isao, Suzuki, Sadao, Watanabe, Miki, Kuriki, Kiyonori, Arisawa, Kokichi, Katsuura-Kamano, Sakurako, Yamasaki, Sho, Ikezaki, Hiroaki, Oze, Isao, Koyanagi, Yuriko N., Mikami, Haruo, Nakamura, Yohko, Takeuchi, Kenji, Kita, Yoshikuni, and Wakai, Kenji

Published
2022
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21. Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium

Author

Inker, Lesley A, Grams, Morgan E, Levey, Andrew S, Coresh, Josef, Cirillo, Massimo, Collins, John F, Gansevoort, Ron T, Gutierrez, Orlando M, Hamano, Takayuki, Heine, Gunnar H, Ishikawa, Shizukiyo, Jee, Sun Ha, Kronenberg, Florian, Landray, Martin J, Miura, Katsuyuki, Nadkarni, Girish N, Peralta, Carmen A, Rothenbacher, Dietrich, Schaeffner, Elke, Sedaghat, Sanaz, Shlipak, Michael G, Zhang, Luxia, van Zuilen, Arjan D, Hallan, Stein I, Kovesdy, Csaba P, Woodward, Mark, Levin, Adeera, Astor, Brad, Appel, Larry, Greene, Tom, Chen, Teresa, Chalmers, John, Arima, Hisatomi, Perkovic, Vlado, Yatsuya, Hiroshi, Tamakoshi, Koji, Li, Yuanying, Hirakawa, Yoshihisa, Matsushita, Kunihiro, Grams, Morgan, Sang, Yingying, Polkinghorne, Kevan, Chadban, Steven, Atkins, Robert, Djurdjev, Ognjenka, Liu, Lisheng, Zhao, Minghui, Wang, Fang, Wang, Jinwei, Ebert, Natalie, Martus, Peter, Tang, Mila, Heine, Gunnar, Emrich, Insa, Seiler, Sarah, Zawada, Adam, Nally, Joseph, Navaneethan, Sankar, Schold, Jesse, Shlipak, Michael, Sarnak, Mark, Katz, Ronit, Hiramoto, Jade, Iso, Hiroyasu, Yamagishi, Kazumasa, Umesawa, Mitsumasa, Muraki, Isao, Fukagawa, Masafumi, Maruyama, Shoichi, Hasegawa, Takeshi, Fujii, Naohiko, Wheeler, David, Emberson, John, Townend, John, Landray, Martin, Brenner, Hermann, Schöttker, Ben, Saum, Kai-Uwe, Fox, Caroline, Hwang, Shih-Jen, Köttgen, Anna, Schneider, Markus P, Eckardt, Kai-Uwe, Green, Jamie, Kirchner, H Lester, and Chang, Alex R

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Women's Health, Clinical Research, Kidney Disease, Renal and urogenital, Good Health and Well Being, Aged, Albuminuria, Blood Chemical Analysis, Creatinine, Cross-Sectional Studies, Disease Progression, Female, Global Health, Glomerular Filtration Rate, Humans, Hypertension, Renal, Internationality, Kidney Function Tests, Male, Middle Aged, Predictive Value of Tests, Renal Insufficiency, Chronic, Retrospective Studies, Sensitivity and Specificity, Severity of Illness Index, Urinalysis, CKD Prognosis Consortium, CKD stage, Chronic kidney disease, albuminuria, anemia, diabetes, glomerular filtration rate, hematocrit, hemoglobin, hyperparathyroidism, hypertension, individual-level meta-analysis, kidney function, laboratory abnormality, laboratory tests, meta-analysis, serum bicarbonate, serum calcium, serum intact parathyroid hormone, serum phosphorus, serum potassium, staging system, Public Health and Health Services, Urology & Nephrology, Clinical sciences
Abstract

Rationale & objectiveChronic kidney disease (CKD) is complicated by abnormalities that reflect disruption in filtration, tubular, and endocrine functions of the kidney. Our aim was to explore the relationship of specific laboratory result abnormalities and hypertension with the estimated glomerular filtration rate (eGFR) and albuminuria CKD staging framework.Study designCross-sectional individual participant-level analyses in a global consortium.Setting & study populations17 CKD and 38 general population and high-risk cohorts.Selection criteria for studiesCohorts in the CKD Prognosis Consortium with data for eGFR and albuminuria, as well as a measurement of hemoglobin, bicarbonate, phosphorus, parathyroid hormone, potassium, or calcium, or hypertension.Data extractionData were obtained and analyzed between July 2015 and January 2018.Analytical approachWe modeled the association of eGFR and albuminuria with hemoglobin, bicarbonate, phosphorus, parathyroid hormone, potassium, and calcium values using linear regression and with hypertension and categorical definitions of each abnormality using logistic regression. Results were pooled using random-effects meta-analyses.ResultsThe CKD cohorts (n=254,666 participants) were 27% women and 10% black, with a mean age of 69 (SD, 12) years. The general population/high-risk cohorts (n=1,758,334) were 50% women and 2% black, with a mean age of 50 (16) years. There was a strong graded association between lower eGFR and all laboratory result abnormalities (ORs ranging from 3.27 [95% CI, 2.68-3.97] to 8.91 [95% CI, 7.22-10.99] comparing eGFRs of 15 to 29 with eGFRs of 45 to 59mL/min/1.73m2), whereas albuminuria had equivocal or weak associations with abnormalities (ORs ranging from 0.77 [95% CI, 0.60-0.99] to 1.92 [95% CI, 1.65-2.24] comparing urinary albumin-creatinine ratio > 300 vs < 30mg/g).LimitationsVariations in study era, health care delivery system, typical diet, and laboratory assays.ConclusionsLower eGFR was strongly associated with higher odds of multiple laboratory result abnormalities. Knowledge of risk associations might help guide management in the heterogeneous group of patients with CKD.

Published
2019

22. Coronary Artery Calcium Progression Among the US and Japanese Men

Author

Hisamatsu, Takashi, Liu, Kiang, Chan, Cheeling, Krefman, Amy E, Fujiyoshi, Akira, Budoff, Matthew J, Miura, Katsuyuki, Lloyd-Jones, Donald M, and Ueshima, Hirotsugu

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Behavioral and Social Science, Clinical Research, Heart Disease - Coronary Heart Disease, Heart Disease, Atherosclerosis, Prevention, Cardiovascular, Black or African American, Aged, Asian, Computed Tomography Angiography, Coronary Angiography, Coronary Artery Disease, Disease Progression, Health Status Disparities, Hispanic or Latino, Humans, Incidence, Japan, Longitudinal Studies, Male, Middle Aged, Prognosis, Prospective Studies, Racial Groups, Risk Assessment, Risk Factors, Severity of Illness Index, United States, Vascular Calcification, White People, coronary disease, ethnic groups, humans, risk factors, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

Background The risk of coronary heart disease remains low in Japan, although distributions of several coronary risk factors have become comparable with those in the United States. We prospectively compared coronary atherosclerosis burden, measured with coronary artery calcium (CAC) progression, between men in the 2 countries. Methods In 2 population-based samples of 1712 US White, Black, Hispanic, Chinese men (baseline, 2000-2002) and 697 Japanese men in Japan (2006-2008) aged 45-74 years without clinical cardiovascular disease, we quantified CAC progression by serial computed tomography with medians of 3.4 and 5.2 years between scans, respectively. Results Among White, Black, Hispanic, Chinese, and Japanese men free of baseline CAC, CAC incidence was observed in 35.2%, 26.9%, 29.2%, 18.9%, and 29.2%, respectively. After adjustment for times between scans, demographics, behaviors, coronary risk factors, and their changes between scans, White men had significantly higher CAC incidence than Japanese men (relative risk, 1.68; 95% CI, 1.13-2.50). Among those with detectable baseline CAC, after similar adjustments, all the US race/ethnic groups had significantly greater annual changes in CAC score (mean [95% CI]: 39.4 [35.2-43.6] for White, 26.9 [21.4-32.4] for Black, 30.6 [24.7-36.5] for Hispanic, and 30.2 [22.6-37.8] for Chinese men) than Japanese men (15.9 [10.1-21.8]). Conclusions We found a higher CAC incidence among US White men and greater increases in existing CAC among all the US race/ethnic groups than among Japanese men in Japan. These differences persisted despite adjustment for differences in coronary risk factors.

Published
2019

23. Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium

Author

Chang, Alex R, Grams, Morgan E, Ballew, Shoshana H, Bilo, Henk, Correa, Adolfo, Evans, Marie, Gutierrez, Orlando M, Hosseinpanah, Farhad, Iseki, Kunitoshi, Kenealy, Timothy, Klein, Barbara, Kronenberg, Florian, Lee, Brian J, Li, Yuanying, Miura, Katsuyuki, Navaneethan, Sankar D, Roderick, Paul J, Valdivielso, Jose M, Visseren, Frank LJ, Zhang, Luxia, Gansevoort, Ron T, Hallan, Stein I, Levey, Andrew S, Matsushita, Kunihiro, Shalev, Varda, Woodward, Mark, Astor, Brad, Appel, Larry, Greene, Tom, Chen, Teresa, Chalmers, John, Arima, Hisatomi, Perkovic, Vlado, Yatsuya, Hiroshi, Tamakoshi, Koji, Hirakawa, Yoshihisa, Coresh, Josef, Sang, Yingying, Polkinghorne, Kevan, Chadban, Steven, Atkins, Robert, Levin, Adeera, Djurdjev, Ognjenka, Klein, Ron, Lee, Kristine, Liu, Lisheng, Zhao, Minghui, Wang, Fang, Wang, Jinwei, Tang, Mila, Heine, Gunnar, Emrich, Insa, Zawada, Adam, Bauer, Lucie, Nally, Joseph, Schold, Jesse, Shlipak, Michael, Sarnak, Mark, Katz, Ronit, Hiramoto, Jade, Iso, Hiroyasu, Yamagishi, Kazumasa, Umesawa, Mitsumasa, Muraki, Isao, Fukagawa, Masafumi, Maruyama, Shoichi, Hamano, Takayuki, Hasegawa, Takeshi, Fujii, Naohiko, Jafar, Tazeen, Hatcher, Juanita, Poulter, Neil, Chaturvedi, Nish, Wheeler, David, Emberson, John, Townend, John, Landray, Martin, Brenner, Hermann, Schöttker, Ben, Saum, Kai-Uwe, Rothenbacher, Dietrich, Fox, Caroline, Hwang, Shih-Jen, Köttgen, Anna, Schneider, Markus P, Eckardt, Kai-Uwe, Green, Jamie, Kirchner, H Lester, Ito, Sadayoshi, Miyazaki, Mariko, Nakayama, Masaaki, Yamada, Cirillo, Massimo, Romundstad, Solfrid, Øvrehus, Marius, Langlo, Knut Asbjørn, Irie, Fujiko, Sairenchi, Toshimi, Rebholz, Casey M, and Young, Bessie

Subjects
Epidemiology, Health Sciences, Obesity, Kidney Disease, Cardiovascular, Aging, Prevention, Nutrition, Clinical Research, Good Health and Well Being, Adiposity, Adult, Aged, Aged, 80 and over, Body Height, Body Mass Index, Cohort Studies, Female, Glomerular Filtration Rate, Humans, Kidney Failure, Chronic, Male, Middle Aged, Mortality, Risk Factors, Waist Circumference, CKD Prognosis Consortium, Clinical Sciences, Public Health and Health Services, General & Internal Medicine, Biomedical and clinical sciences, Health sciences, Psychology
Abstract

ObjectiveTo evaluate the associations between adiposity measures (body mass index, waist circumference, and waist-to-height ratio) with decline in glomerular filtration rate (GFR) and with all cause mortality.DesignIndividual participant data meta-analysis.SettingCohorts from 40 countries with data collected between 1970 and 2017.ParticipantsAdults in 39 general population cohorts (n=5 459 014), of which 21 (n=594 496) had data on waist circumference; six cohorts with high cardiovascular risk (n=84 417); and 18 cohorts with chronic kidney disease (n=91 607).Main outcome measuresGFR decline (estimated GFR decline ≥40%, initiation of kidney replacement therapy or estimated GFR

Published
2019

24. Metabolic changes induced by dapagliflozin, an SGLT2 inhibitor, in Japanese patients with type 2 diabetes treated by oral anti-diabetic agents: A randomized, clinical trial

Author

Horibe, Kayo, Morino, Katsutaro, Miyazawa, Itsuko, Tanaka-Mizuno, Sachiko, Kondo, Keiko, Sato, Daisuke, Ohashi, Natsuko, Ida, Shogo, Yanagimachi, Tsuyoshi, Yoshimura, Masahiro, Itoh, Ryuta, Murata, Kiyoshi, Miura, Katsuyuki, Arima, Hisatomi, Fujita, Yukihiro, Ugi, Satoshi, and Maegawa, Hiroshi

Published
2022
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29. Association of Pro-Inflammatory Diet with Long-Term Risk of All-Cause and Cardiovascular Disease Mortality: NIPPON DATA80

Author

Ganbaatar, Gantsetseg, primary, Okami, Yukiko, additional, Kadota, Aya, additional, Ganbaatar, Namuun, additional, Yano, Yuichiro, additional, Kondo, Keiko, additional, Harada, Akiko, additional, Okuda, Nagako, additional, Yoshita, Katsushi, additional, Okamura, Tomonori, additional, Okayama, Akira, additional, Ueshima, Hirotsugu, additional, and Miura, Katsuyuki, additional

Published
2024
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30. Association of Anthropometric and CT-Based Obesity Indices with Subclinical Atherosclerosis

Author

Higo, Yosuke, primary, Hisamatsu, Takashi, additional, Nakagawa, Yoshihisa, additional, Sawayama, Yuichi, additional, Yano, Yuichiro, additional, Kadota, Aya, additional, Fujiyoshi, Akira, additional, Kadowaki, Sayaka, additional, Torii, Sayuki, additional, Kondo, Keiko, additional, Watanabe, Yoshiyuki, additional, Ueshima, Hirotsugu, additional, and Miura, Katsuyuki, additional

Published
2024
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31. A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern

Author

Suzuki, Harumitsu, Nakamura, Yasuyuki, Matsuo, Keitaro, Imaeda, Nahomi, Goto, Chiho, Narita, Akira, Shimizu, Atsushi, Takashima, Naoyuki, Matsui, Kenji, Miura, Katsuyuki, Nakatochi, Masahiro, Hishida, Asahi, Shimanoe, Chisato, Nishimoto, Daisaku, Takezaki, Toshiro, Oze, Isao, and Ito, Hidemi

Subjects
Genetic research, Genetic variation -- Research, Genome-wide association studies, Food habits -- Genetic aspects, Food/cooking/nutrition, Health
Abstract

Background/Objectives Individual eating habits may be influenced by genetic factors, in addition to environmental factors. Previous studies suggested that adherence to Japanese food patterns was associated with a decreased risk of all-cause and cardiovascular disease mortality. We conducted a genome-wide association study (GWAS) in a Japanese population to find genetic variations that affect adherence to a Japanese food pattern. Subjects/Methods We analyzed GWAS data using 14,079 participants from the Japan Multi-Institutional Collaborative Cohort study. We made a Japanese food score based on six food groups. Association of the imputed variants with the Japanese food score was performed by linear regression analysis with adjustments for age, sex, total energy intake, alcohol intake (g/day), and principal components 1-10 omitting variants in the major histocompatibility region. Results We found one SNP in the 14q11.2 locus that was significantly associated with the Japanese food score with P values Conclusion We found a new SNP that was associated with the Japanese food score in a Japanese population. This SNP is inversely associated with genes link to olfaction and obesity., Author(s): Harumitsu Suzuki [sup.1] [sup.2] , Yasuyuki Nakamura [sup.3] [sup.4] , Keitaro Matsuo [sup.5] [sup.6] , Nahomi Imaeda [sup.7] [sup.8] , Chiho Goto [sup.8] [sup.9] , Akira Narita [sup.10] , [...]

Published
2021
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32. Alcohol drinking and brain morphometry in apparently healthy community-dwelling Japanese men

Author

Horie, Minoru, Nakagawa, Yoshihisa, Yamamoto, Takashi, Nakano, Yasutaka, Ogawa, Emiko, Maegawa, Hiroshi, Morino, Katsutaro, Miyazawa, Itsuko, Watanabe, Yoshiyuki, Nozaki, Kazuhiko, Tooyama, Ikuo, Shiino, Akihiko, Andoh, Akira, Tsuru, Teruhiko, Ogita, Hisakazu, Miyamatsu, Naomi, Nakamura, Yasuyuki, Kadota, Aya, Kondo, Keiko, Torii, Sayuki, Kadowaki, Takashi, Kadowaki, Sayaka, Suzuki, Sentaro, Ito, Takahiro, Kunimura, Ayako, Segawa, Hiroyoshi, Fujiyoshi, Akira, Higashiyama, Aya, Okamura, Tomonori, Azuma, Koichiro, Sawamura, Tatsuya, Igase, Michiya, Tabara, Yasuharu, Sekikawa, Akira, Barinas-Mitchell, Emma J.M., Edmundowicz, Daniel, Ohkubo, Takayoshi, Hozawa, Atsushi, Murakami, Yoshitaka, Okuda, Nagako, Arima, Hisatomi, Satoh, Atsushi, Kita, Yoshikuni, Hisamatsu, Takashi, Yanagita, Masahiko, Abbott, Robert D., Ohno, Seiko, Takashima, Naoyuki, Miyagawa, Naoko, Zaid, Maryam, Saito, Yoshino, Syaifullah, Ali Haidar, Moniruzzaman, Mohammad, Waki, Takashi, Ueshima, Hirotsugu, and Miura, Katsuyuki

Published
2021
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34. Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets

Author

Matsushita, Kunihiro, Jassal, Simerjot K, Sang, Yingying, Ballew, Shoshana H, Grams, Morgan E, Surapaneni, Aditya, Arnlov, Johan, Bansal, Nisha, Bozic, Milica, Brenner, Hermann, Brunskill, Nigel J, Chang, Alex R, Chinnadurai, Rajkumar, Cirillo, Massimo, Correa, Adolfo, Ebert, Natalie, Eckardt, Kai-Uwe, Gansevoort, Ron T, Gutierrez, Orlando, Hadaegh, Farzad, He, Jiang, Hwang, Shih-Jen, Jafar, Tazeen H, Kayama, Takamasa, Kovesdy, Csaba P, Landman, Gijs W, Levey, Andrew S, Lloyd-Jones, Donald M, Major, Rupert W., Miura, Katsuyuki, Muntner, Paul, Nadkarni, Girish N, Naimark, David MJ, Nowak, Christoph, Ohkubo, Takayoshi, Pena, Michelle J, Polkinghorne, Kevan R, Sabanayagam, Charumathi, Sairenchi, Toshimi, Schneider, Markus P, Shalev, Varda, Shlipak, Michael, Solbu, Marit D, Stempniewicz, Nikita, Tollitt, James, Valdivielso, José M, van der Leeuw, Joep, Wang, Angela Yee-Moon, Wen, Chi-Pang, Woodward, Mark, Yamagishi, Kazumasa, Yatsuya, Hiroshi, Zhang, Luxia, Schaeffner, Elke, and Coresh, Josef

Published
2020
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41. Association between Dietary Patterns and Serum Low Density Lipoprotein Cholesterol in Japanese Women and Men: The Japan Multi-Institutional Collaborative Cohort (J-MICC) Study

Author

Kitaoka, Kaori, primary, Miura, Katsuyuki, additional, Takashima, Naoyuki, additional, Kadota, Aya, additional, Harada, Akiko, additional, Nakamura, Yasuyuki, additional, Kita, Yoshikuni, additional, Yano, Yuichiro, additional, Tamura, Takashi, additional, Nagayoshi, Mako, additional, Okada, Rieko, additional, Kubo, Yoko, additional, Suzuki, Sadao, additional, Nishiyama, Takeshi, additional, Tanoue, Shiroh, additional, Koriyama, Chihaya, additional, Kuriki, Kiyonori, additional, Arisawa, Kokichi, additional, Katsuura-Kamano, Sakurako, additional, Nishida, Yuichiro, additional, Shimanoe, Chisato, additional, Ozaki, Etsuko, additional, Matsui, Daisuke, additional, Ikezaki, Hiroaki, additional, Otonari, Jun, additional, Oze, Isao, additional, Koyanagi, Yuriko N., additional, Nakamura, Yohko, additional, Kusakabe, Miho, additional, Wakai, Kenji, additional, and Matsuo, Keitaro, additional

Published
2023
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45. Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80

Author

Miyazawa, Itsuko, Miura, Katsuyuki, Miyagawa, Naoko, Kondo, Keiko, Kadota, Aya, Okuda, Nagako, and Fujiyoshi, Akira

Subjects
Fiber in human nutrition -- Health aspects, Carbohydrates -- Health aspects, Cardiovascular diseases -- Risk factors, Food/cooking/nutrition, Health
Abstract

Background/Objectives The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population. Subjects/Methods We prospectively followed 8925 participants (3916 men and 5009 women) aged 30-79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Cox proportional hazards models were used to estimate multivariable-adjusted hazard ratios (HRs) and their 95% confidence intervals (CIs) for CVD mortality by quartiles of exposure variables. Results During 24 years of follow-up, 823 CVD deaths were observed. In men, the multivariable-adjusted HR for CVD mortality was lower in the highest quartile of DF intake (HR: 0.64; 95% CI: 0.47-0.87; P.sub.trend = 0.007) compared with the lowest quartile. This association was not significant in women. Multivariable-adjusted HR for total stroke mortality was lower in the highest quartile of DF intake (HR: 0.61; 95% CI: 0.38-0.98; P.sub.trend = 0.046) compared with the lowest quartile in women. Carbohydrate, available carbohydrate, and starch intake were not associated with CVD mortality. Conclusions Higher intake of DF was associated significantly with a lower risk of CVD mortality in men and lower risk of stroke mortality in women. Intake of carbohydrate, available carbohydrate, and starch were not associated with the risk of CVD mortality in men or women., Author(s): Itsuko Miyazawa [sup.1] , Katsuyuki Miura [sup.2] [sup.3] , Naoko Miyagawa [sup.2] [sup.4] , Keiko Kondo [sup.2] , Aya Kadota [sup.2] [sup.3] , Nagako Okuda [sup.5] , Akira Fujiyoshi [...]

Published
2020
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47. Statement of the Asian Hypertension Society Network: the Okinawa Declaration on the unity of hypertension societies in Asian countries and regions to overcome hypertension and hypertension-related diseases

Author

Ohya, Yusuke, Kario, Kazuomi, Itoh, Hiroshi, Nishiyama, Akira, Ishimitsu, Toshihiko, Ichihara, Atsuhiro, Kai, Hisashi, Kashihara, Naoki, Katsuya, Tomohiro, Miura, Katsuyuki, Mukoyama, Masashi, Nakamura, Satoko, Node, Koichi, Ohishi, Mitsuru, Saito, Shigeyuki, Shibata, Hirotaka, Shimosawa, Tatsuo, Tamura, Kouichi, Toyoda, Kazunori, Ali, Mohd Arifin Mohd, Chia, Yook-Chin, Constantine, Godwin, Erwinanto, Erwinanto, Ihm, Sang Hyun, Kao, Hsien-Li, Van Minh, Huynh, Narasingan, S. N., Ona, Deborah Ignacia D., Siddique, Saulat, Sukonthasarn, Apichard, Teo, Boon Wee, Unurjargal, Tsolmon, Wang, Ji-Guang, Wang, Tzung-Dau, and Raukgi, Hiromi

Published
2022
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