335 results on '"Mittermaier, Anthony"'
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2. Modulating the selectivity of inhibitors for prolyl oligopeptidase inhibitors and fibroblast activation protein-α for different indications
3. Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors
4. Binding interactions in a kinase active site modulate background ATP hydrolysis
5. An allosteric switch regulates Mycobacterium tuberculosis ClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR
6. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors
7. A naturally occurring G11S mutation in the 3C‐like protease from the SARS‐CoV‐2 virus dramatically weakens the dimer interface
8. New Tools Provide New Insights in NMR Studies of Protein Dynamics
9. Integration of Computational and Experimental Techniques for the Discovery of SARS-CoV-2 PLpro Covalent Inhibitors
10. G-quadruplex dynamics
11. Covalent inhibitors design and discovery
12. Determination of pKa Values in Intrinsically Disordered Proteins
13. A sensitive and scalable fluorescence anisotropy single stranded RNA targeting approach for monitoring riboswitch conformational states.
14. i-Motif folding intermediates with zero-nucleotide loops are trapped by 2'-fluoroarabinocytidine via F···H and O···H hydrogen bonds
15. A naturally occurring G11S mutation in the 3C‐like protease from the SARS‐CoV‐2 virus dramatically weakens the dimer interface.
16. Minimizing Product Inhibition in DNA Self‐Replication: Insights for Prebiotic Replication from the Role of the Enzyme in Lesion‐Induced DNA Amplification
17. Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization
18. Global ITC fitting methods in studies of protein allostery
19. Computational and Biophysical Methods for the Discovery and Optimization of Covalent Drugs
20. Minimizing Product Inhibition in DNA Self-Replication: Insights for Prebiotic Replication from the Role of the Enzyme in Lesion-Induced DNA Amplification
21. Structural Polymorphism of Guanine Quadruplex-Containing Regions in Human Promoters
22. Electrostatic Interactions in the Binding Pathway of a Transient Protein Complex Studied by NMR and Isothermal Titration Calorimetry
23. Rapid measurement of inhibitor binding kinetics by isothermal titration calorimetry
24. Concerted millisecond timescale dynamics in the intrinsically disordered carboxyl terminus of γ‐tubulin induced by mutation of a conserved tyrosine residue
25. Relaxation dispersion NMR spectroscopy for the study of protein allostery
26. Van ‘t Hoff global analyses of variable temperature isothermal titration calorimetry data
27. Concerted Dynamics Link Allosteric Sites in the PBX Homeodomain
28. Using transient equilibria (TREQ) to measure the thermodynamics of slowly assembling supramolecular systems
29. Conformational plasticity surrounding the active site of NADH oxidase from Thermus thermophilus
30. Observing biological dynamics at atomic resolution using NMR
31. ZZ-Exchange
32. Tuning DNA Supramolecular Polymers by the Addition of Small, Functionalized Nucleobase Mimics
33. Using transient equilibria (TREQ) to measure the thermodynamics of slowly assembling supramolecular systems
34. EDTA-Gradient Loading of Doxorubicin into Ferrocene-Containing Liposomes: Effect of Lipid Composition and Visualization of Triggered Release by Cryo-TEM
35. Design, Synthesis and Biological Evaluation of Novel SARS-CoV-2 3CLpro Covalent Inhibitors
36. Characterizing Bi-substrate Enzyme Kinetics at High Resolution by 2D-ITC
37. Binding interactions in a kinase active site modulate background ATP hydrolysis
38. Active site dynamics in NADH oxidase from Thermus thermophilus studied by NMR spin relaxation
39. Protein alignment using cellulose nanocrystals: practical considerations and range of application
40. Computer-aided design, synthesis, and biological evaluation of [4.3.0] bicyclic prolyl oligopeptidase and fibroblast activation protein-α dual inhibitors
41. Transient equilibrium mapping: A new tool for measuring the thermodynamics of slowly assembling supramolecular systems
42. Cross-correlated spin relaxation effects in methyl 1H CPMG-based relaxation dispersion experiments: Complications and a simple solution
43. Applications of isothermal titration calorimetry in pure and applied research from 2016 to 2020
44. COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
45. Frustrated folding of guanine quadruplexes in telomeric DNA
46. Analyzing Protein–Ligand Interactions by Dynamic NMR Spectroscopy
47. Side-chain interactions in the folding pathway of a Fyn SH3 domain mutant studied by relaxation dispersion NMR spectroscopy
48. NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain
49. Effect of deuteration on some structural parameters of methyl groups in proteins as evaluated by residual dipolar couplings
50. Parallel reaction pathways accelerate folding of a guanine quadruplex
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