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7. ISMPO Guidelines for Diagnosis and Management of Early Breast Cancer.

Author

Singh, Randeep, Sarin, Aditya, Kulkarni, Padmaj, Verma, Amit, Rathi, Arun, Smruti, B. Koppikar, Gupta, Deepika, Govind Babu, Kanakasetty, Malhotra, Hemant, Bajpai, Jyoti, Chandra, Madhavi, Parikh, Purvish, Sharma, Shambhavi, Badwal, Sonia, Mittal, Shivani, Sud, Seema, Gupta, Sudeep, Nag, Shona, Radhakrishnan, Venkat, and Aggarwal, Shyam

Subjects
PEDIATRIC oncology, BREAST cancer, MEDICAL societies, EXPERT evidence, CANCER treatment
Abstract

The management of breast cancer has become increasingly complex and multidisciplinary in the recent past. Further, there are unique constraints and opportunities for cancer care delivery in India, including socioeconomic, geographic, and other disparities. Therefore, the Indian Society of Medical and Paediatric Oncology convened a panel of experts to create evidence and context-based guidelines for the management of early breast cancer. [ABSTRACT FROM AUTHOR]

Published
2025
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14. Contributors

Author

Abd Elhaliem, Eman R., Abd-Elbaset, Mohamed, Aggarwal, Shyam, Ahmed, Noha A., Ahmed, Osama M., Bansal, Seema, Bansal, Sudha, Batra, Gitika, Bhardwaj, Puneet, Bhatia, Anmol, Bisht, Ramila, Bose, Sudeep, Chopra, Mani, Choudhary, Gajendra, Dhir, Neha, Ghosh, Asit Ranjan, Gill, Rajwant K., Gill, Sikander S., Gosipatala, Sunil Babu, Jain, Ashish, Jain, Shweta, Joshi, Rupa, Kadian, Monika, Kaur, Gurjeet, Kaur, Hardeep, Khalko, Raj Kumar, Kuhad, Anurag, Kumar, Anil, Kumar, Subodh, Kumari, Sneha, Kundu, Satyabrata, Majhi, Anjoy, Malik, Deepti, Masih, Gladson David, Medhi, Bikash, Mehra, Sweety, Menon, Shaveta, Mishra, Madhusmita, Mittal, Shivani Arora, Pandeya, Abhishek, Paul, Sandip, Prabha, Praisy K., Prajapat, Manisha, Prakash, Ajay, Prasad, Peeyush, Saini, Neetu, Sardar, Pinki Saha, Sharma, Amit Raj, Sharma, Anuradha, Sharma, Indu, Sharma, Madhu, Sharma, Saurabh, Sharma, Siddharth, Singh, Ashutosh, Singh, Rahul Soloman, Singh, Shamsher, Sinha, Shweta, Sobti, R.C., Srivastava, Shriyansh, Suroy, Benjamin, Taimoor, Nida, Tushir, Shiva, Tyagi, Bulbul, Ulkarsha, and Yadav, Monu

Published
2024
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17. A novel Plasmodium falciparum rhoptry associated adhesin mediates erythrocyte invasion through the sialic-acid dependent pathway

Author

Anand, Gaurav, primary, Reddy, K. Sony, additional, Pandey, Alok Kumar, additional, Mian, Syed Yusuf, additional, Singh, Hina, additional, Mittal, Shivani Arora, additional, Amlabu, Emmanuel, additional, Bassat, Quique, additional, Mayor, Alfredo, additional, Chauhan, Virander Singh, additional, and Gaur, Deepak, additional

Published
2016
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18. ISMPO Guidelines for Diagnosis and Management of Early Breast Cancer

Author

Singh, Randeep, Sarin, Aditya, Kulkarni, Padmaj, Verma, Amit, Rathi, Arun, Smruti, B. Koppikar, Gupta, Deepika, Govind Babu, Kanakasetty, Malhotra, Hemant, Bajpai, Jyoti, Chandra, Madhavi, Parikh, Purvish, Sharma, Shambhavi, Badwal, Sonia, Mittal, Shivani, Sud, Seema, Gupta, Sudeep, Nag, Shona, Radhakrishnan, Venkat, and Aggarwal, Shyam

Published
2024
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19. Regulation Of Human Cathepsin L Expression By AAAT Repeats

Author

Sharma, Lokesh Kumar, Mittal, Shivani, Singh, Ratnakar, Chauhan, Shyam Singh, Sharma, Lokesh Kumar, Mittal, Shivani, Singh, Ratnakar, and Chauhan, Shyam Singh

Abstract

Over expression and secretion of human cathepsin L, a lysosomal cysteine protease, is one of the major determinants for the gain in metastatic ability of cancer cells. However, in humans, this protease is regulated at multiple levels. In this study, we have explored the significance of a repeat region present in its alternate promoter. Sequencing this region in seven different cancer cell lines revealed the presence of either eight or ten repeats. Cell lines with ten repeats displayed higher cathepsin L mRNA and protein expression. Further, recombinant reporter constructs containing either eight or ten repeats upstream to luciferase were transfected in cell lines to analyze their transcription regulation abilities. We observed that the construct with ten repeats resulted in higher transcription, albeit in a tissue specific manner. This is the first report demonstrating the involvement of a tandem repeat element in regulating cathepsin L expression.

Published
2015

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