1. Clinical application of 2.16% hypertonic saline solution to correct the blood sodium concentration in diarrheic calves with hyponatremia
- Author
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Yoshiki Murakami, Marina Otsuka, Kazuyuki Suzuki, Mitsuhide Nakagawa, Hiroetsu Suzuki, and Kenji Tsukano
- Subjects
Diarrhea ,medicine.medical_specialty ,hyponatremia ,040301 veterinary sciences ,Blood sodium ,Cattle Diseases ,Body weight ,Gastroenterology ,0403 veterinary science ,03 medical and health sciences ,Internal medicine ,Internal Medicine ,medicine ,Animals ,030304 developmental biology ,Saline Solution, Hypertonic ,calf ,0303 health sciences ,General Veterinary ,Hypertonic Saline Solution ,business.industry ,Sodium ,04 agricultural and veterinary sciences ,Note ,medicine.disease ,2.16% hypertonic saline solution ,Cattle ,Female ,medicine.symptom ,Hyponatremia ,business - Abstract
The aim of this study was to examine whether 2.16% hypertonic saline solution (HSS) is useful for the treatment of diarrheic calves with hyponatremia. Eleven of 13 female Holstein calves exhibiting moderate diarrhea and hyponatremia received 1,250 ml of 2.16% HSS over 15 min regardless of body weight. The remaining two calves that were unable to stand and had severe hyponatremia received 2,500 ml of 2.16% HSS intravenously over 30 min. As a result, hyponatremia in all diarrheic calves was significantly improved by the administration of 2.16% HSS from 122.2 ± 7.0 mEq/l at pre to 134.8 ± 3.7 mEq/l at post, which was above the threshold of 132 mEq/l for hyponatremia. Therefore, 2.16% HSS may be useful for hyponatremia in calves with diarrhea.
- Published
- 2020