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1. Improving GENCODE reference gene annotation using a high-stringency proteogenomics workflow

Author

James C. Wright, Jonathan Mudge, Hendrik Weisser, Mitra P. Barzine, Jose M. Gonzalez, Alvis Brazma, Jyoti S. Choudhary, and Jennifer Harrow

Subjects
Science
Abstract

Identifying and annotating functional elements in the human genome remains a challenging but important task. Here the authors propose a priority annotation score to rank identifications and suggest how proteogenomics evidence can be interpreted and what additional information substantiates protein-coding potential for annotation.

Published
2016
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