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642 results on '"Mishra DR"'

1. Anaphylactic reactions due to pantoprazole: case report of two cases

Author

Gupta PP, Bhandari R, Mishra DR, Agrawal KK, Jirel S, and Malla G

Subjects
anaphylactic reactions, pantoprazole, proton pump inhibitors, Medicine (General), R5-920
Abstract

Pramendra Prasad Gupta,1 Rabin Bhandari,1 Deebya Raj Mishra,2 Krishna Kumar Agrawal,3 Rupak Bhandari,1 Sunil Jirel,1 Gyanendra Malla1 1Department of General Practice and Emergency Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal; 2Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal; 3Department of Internal Medicine, Nepal Medical College and Teaching Hospital, Kathmandu, Nepal Background: Drug-induced hypersensitivity reaction is of great clinical significance in therapeutics. The objective of this reporting of two cases is to show that anaphylaxis reaction can occur with pantoprazole. Case summaries: A 38-year-old female reported to the emergency ward in a critical condition, with a history of periorbital edema, edema of the skin, pruritus, nausea, vomiting, and difficulty breathing 20 minutes after ingestion of a pantoprazole 40 mg tablet. A 32-year-old female reported to the emergency ward in a critical condition, with complaints of rashes all over the body, itching on the whole body, and swollen lips and eyes after ingestion of a pantoprazole 40 mg tablet. Conclusion: It is necessary for all health care providers to know that pantoprazole can cause anaphylaxis, which is a life-threatening reaction, and to be cautious while prescribing it. Keywords: anaphylactic reactions, pantoprazole, proton pump inhibitors

Published
2018

2. Speech Diarization and ASR with GMM

Author

Sharma, Aayush Kumar, Bhavikatti, Vineet, Nidawani, Amogh, Siddappaji, P, Sanath, and Mishra, Dr Geetishree

Subjects
Electrical Engineering and Systems Science - Audio and Speech Processing, Computer Science - Machine Learning, Computer Science - Sound
Abstract

In this research paper, we delve into the topics of Speech Diarization and Automatic Speech Recognition (ASR). Speech diarization involves the separation of individual speakers within an audio stream. By employing the ASR transcript, the diarization process aims to segregate each speaker's utterances, grouping them based on their unique audio characteristics. On the other hand, Automatic Speech Recognition refers to the capability of a machine or program to identify and convert spoken words and phrases into a machine-readable format. In our speech diarization approach, we utilize the Gaussian Mixer Model (GMM) to represent speech segments. The inter-cluster distance is computed based on the GMM parameters, and the distance threshold serves as the stopping criterion. ASR entails the conversion of an unknown speech waveform into a corresponding written transcription. The speech signal is analyzed using synchronized algorithms, taking into account the pitch frequency. Our primary objective typically revolves around developing a model that minimizes the Word Error Rate (WER) metric during speech transcription.

Published
2023

3. BIOMARKERS

Author

S. Mishra, Dr. Suchitra, primary and N. Mahajan, Dr. Ujwala, additional

Published
2024
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8. Impact of acute kidney injury in patients with acute decompensated heart failure: Cardiorenal syndrome

Author

Sagar Tandel, Dr., Ashish Mishra, Dr., Sharad Jain, Dr., Vishal Sharma, Dr., Kewal Kanabar, Dr., Pooja Vyas, Dr., Krutika Patel, Ms., Nisarg Desai, Dr., and Aman Kedia, Dr.

Subjects
Cardiorenal syndrome, Acute decompensated heart failure, Acute kidney injury, Worsening renal function, Mortality, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Cardiorenal syndrome (CRS) is a complex interdependent relationship between the heart and kidneys, prevalent in hospitalized patients with acute decompensated heart failure (ADHF). The main aim of this study is to evaluation of cardiac and renal function, treatment factors, and outcomes in view of mortality and persistent renal dysfunction in acute decompensated heart failure (cardio renal syndrome type 1) patients. We studied 100 patients hospitalised with ADHF and acute kidney injury (AKI). Patients were evaluated clinically, biochemically, ultrasonographically, and echocardiographically to assess demographics, etiologic and risk factors, cardiac and renal function, and outcomes in view of mortality and persistent renal dysfunction. The study monitored the patients until discharge and follow up with three months to one year. Record information about functional improvement, worsening symptoms, and mortality. The majority of the patients were males (72%), with dyspnea being the most common symptom (92%) followed by decreased urinary output (82%). The mean age of the patients was 62.60 years. Low level of Mean arterial pressure (MAP) 18.97 (95% CI 4.59 to 78.37, P 0.0001), estimated glomerular filtration rate (eGFR) 0.92(95% CI 0.87 to 0.99; P 0.02), maximum creatinine 3.08 (95% CI 1.67 to 5.67, P 0.0001), maximum level of urea 1.02(95% CI, P 0.001), lower Left ventricular ejection fraction (LVEF) 1.05 (95% CI 0.15 to 0.84, P 0.04) were independently predictors of in-hospital mortality. CRS-1 is associated with increased risk of mortality (25%), residual renal dysfunction (16%) at one year follow up. Persistent renal dysfunction, renal replacement therapy possibly improves for the treating persistent renal dysfunction, and recurrent HHF (more than 2 admissions) post hospitalisation index within twelve months were predictors of mortality (25%) at one-year.

Published
2024
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37. Solving a Birkhoff Interpolation Problem for (0, 1, 5) Data

Author

Dr. Rama Nand Mishra, Mishra, Dr. Akhilesh Kumar, Dr. Kulbhushan Singh, Dr. Arunesh Kumar Mishra, Dr. Rama Nand Mishra, Mishra, Dr. Akhilesh Kumar, Dr. Kulbhushan Singh, and Dr. Arunesh Kumar Mishra

Abstract

The following research work deals with a special type of Birkhoff’s interpolation problem in which we have 3 sets of data prescribed in the unit interval I = [0, 1]. Data values are the function value, first derivatives and fifth derivatives prescribed at nodes of the unit interval. We obtained a unique spline interpolating the given data along with the convergence problem.

Published
2024

49. Indian flour mill is perfect explanation of black hole theory

Author

Sharma, Vaidhshiromani Dheeraj, primary, Mishra, Dr. Rajesh Kumar, additional, Dhanraj, Dr. CB, additional, Yadav, Dr. MK, additional, Marde, Dr. Ramakant, additional, Joshi, Dr. SC, additional, Verma, Dr. Anil, additional, Karunakar, Dr. GB, additional, Goswami, Dr. Ashish, additional, Pandey, Dr. Arun, additional, Singh, Dr. Rajeev, additional, Pandey, Dr. Preeti, additional, and Arya, Dr. Neha, additional

Published
2024
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