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131 results on '"Mire-Sluis, Anthony"'

19. Recommendations on risk-based strategies for detection and characterization of antibodies against biotechnology products

Author

Koren, Eugen, primary, Smith, Holly W., additional, Shores, Elizabeth, additional, Shankar, Gopi, additional, Finco-Kent, Deborah, additional, Rup, Bonita, additional, Barrett, Yu-Chen, additional, Devanarayan, Viswanath, additional, Gorovits, Boris, additional, Gupta, Shalini, additional, Parish, Thomas, additional, Quarmby, Valerie, additional, Moxness, Michael, additional, Swanson, Steven J., additional, Taniguchi, Gary, additional, Zuckerman, Linda A., additional, Stebbins, Christopher C., additional, and Mire-Sluis, Anthony, additional

Published
2008
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21. Recommendations for the design, optimization, and qualification of cell-based assays used for the detection of neutralizing antibody responses elicited to biological therapeutics

Author

Gupta, Shalini, primary, Indelicato, Stephen R., additional, Jethwa, Vijay, additional, Kawabata, Thomas, additional, Kelley, Marian, additional, Mire-Sluis, Anthony R., additional, Richards, Susan M., additional, Rup, Bonita, additional, Shores, Elizabeth, additional, Swanson, Steven J., additional, and Wakshull, Eric, additional

Published
2007
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23. Recommendations for the design and optimization of immunoassays used in the detection of host antibodies against biotechnology products

Author

Mire-Sluis, Anthony R, primary, Barrett, Yu Chen, additional, Devanarayan, Viswanath, additional, Koren, Eugen, additional, Liu, Hank, additional, Maia, Mauricio, additional, Parish, Thomas, additional, Scott, George, additional, Shankar, Gopi, additional, Shores, Elizabeth, additional, Swanson, Steven J, additional, Taniguchi, Gary, additional, Wierda, Daniel, additional, and Zuckerman, Linda A, additional

Published
2004
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24. Implications for the assay and biological properties of interleukin-3. Results of a WHO international collaborative study

Author

Mire-Sluis, Anthony R., Das, Rose Gaines, Thorpe, Robin, Thomas, Sandra, Maher, Darryl, Valent, Peter, Payer, Elisabeth, De Groote, Groote, Hayglass, Kent, Ziltener, H., Poulsen, Lars K., Miossec, Pierre, Chomarat, P., Grassi, Jacques, Pawelec, G., Fritzsche, U., Reisbach, G., Sidiropoulos, John, Ben-Sasson, S. Z., Even-Chen, Zeev, Pegoraro, Luigi, Barboni, Francesco, Sugimoto, Kenkichi, Tsuji, K., Matsumoto, Tomoaki, Arai, Kenrichi, Olobo, J., Wagemaker, G., Van Der Pouw-Kraan, T., Sheth, Kirrikant V., Gutierrez, C., Rivas, D., Lyeke, Nils, Schön, Karin, Bews, John P.A., Tullberg, K., Klotzbücher, R., Page, L., Bird, C., McGuckin, Colin P., Gordon, John, Katira, Anita, Openshaw, Peter, Georgiou, Andrew, Testa, Nydia G., Callard, Robin, Paik, K., McKearn, John, Rock, Marie, Harper, Kathleen, Swanson, Steven J., Siegel, Jay P., Spiegelberg, H. L., Geigert, John, Carter, Kerri, Paul, William E., Watson, Cynthia, Tsang, Monica, Zhou, Li, Westreich, Louis, Chao, Chun C., Riss, Terry L., Moravec, Rich, Mire-Sluis, Anthony R., Das, Rose Gaines, Thorpe, Robin, Thomas, Sandra, Maher, Darryl, Valent, Peter, Payer, Elisabeth, De Groote, Groote, Hayglass, Kent, Ziltener, H., Poulsen, Lars K., Miossec, Pierre, Chomarat, P., Grassi, Jacques, Pawelec, G., Fritzsche, U., Reisbach, G., Sidiropoulos, John, Ben-Sasson, S. Z., Even-Chen, Zeev, Pegoraro, Luigi, Barboni, Francesco, Sugimoto, Kenkichi, Tsuji, K., Matsumoto, Tomoaki, Arai, Kenrichi, Olobo, J., Wagemaker, G., Van Der Pouw-Kraan, T., Sheth, Kirrikant V., Gutierrez, C., Rivas, D., Lyeke, Nils, Schön, Karin, Bews, John P.A., Tullberg, K., Klotzbücher, R., Page, L., Bird, C., McGuckin, Colin P., Gordon, John, Katira, Anita, Openshaw, Peter, Georgiou, Andrew, Testa, Nydia G., Callard, Robin, Paik, K., McKearn, John, Rock, Marie, Harper, Kathleen, Swanson, Steven J., Siegel, Jay P., Spiegelberg, H. L., Geigert, John, Carter, Kerri, Paul, William E., Watson, Cynthia, Tsang, Monica, Zhou, Li, Westreich, Louis, Chao, Chun C., Riss, Terry L., and Moravec, Rich

Abstract

Five preparations of interleukin-3 (IL-3) have been evaluated by 28 laboratories in 12 countries for their suitability to serve as an international standard for this material in a joint international collaborative study for IL-3 and interleukin-4 (IL-4). The preparations were assayed in a wide range of in vitro bioassays and immunoassays. It is clear from the biological assays contributed to this study that different recombinant preparations of IL-3 can have very different biological specific activities, including those from the same source (i.e., E. coli). Biological assays of IL-3 were significantly more consistent in their estimates of levels of IL-3 than the immunoassays, suggesting an unusual pattern of epitome recognition amongst the antibodies in the immunoassays. This study also illustrates the point that the level of cytokine measured by immunoassays does not necessarily reflect the biological potency of the cytokine. On the basis of results reported here, with the agreement of the participants of the study and with the authorization of the Expert Committee on Biological Standardization (ECBS) of the World Health Organization (WHO) the preparation of IL-3 (91/510) was established as the international standard for interleukin-3 with an assigned unitage of 1700 IU/ampoule.

Published
1996

25. Implications for the assay and biological activity of interleukin-4. Results of a WHO international collaborative study

Author

Mire-Sluis, Anthony R., Das, Rose Gaines, Thorpe, Robin, Thomas, Sandra, Maher, Darryl, Valent, Peter, Payer, Elisabeth, De Groote, Groote, Hayglass, Kent, Ziltener, H., Poulsen, Lars K., Miossec, Pierre, Chomarat, P., Grassi, Jacques, Pawelec, G., Fritzsche, U., Reisbach, G., Sidiropoulos, John, Ben-Sasson, S. Z., Even-Chen, Zeev, Pegoraro, Luigi, Barboni, Francesco, Sugimoto, Kenkichi, Tsuji, K., Matsumoto, Tomoaki, Arai, Kenrichi, Yokota, Takashi, Olobo, J., Wagemaker, G., Van Der Pouw-Kraan, T., Sheth, Kirrikant V., Gutierrez, C., Rivas, D., Lyeke, Nils, Schön, Karin, Bews, John P.A., Tullberg, K., Klotzbücher, R., Page, L., Bird, C., McGuckin, Colin P., Gordon, John, Katira, Anita, Openshaw, Peter, Georgiou, Andrew, Testa, Nydia G., Callard, Robin, Paik, K., McKearn, John, Rock, Marie, Harper, Kathleen, Swanson, Steven J., Siegel, Jay P., Spiegelberg, H. L., Geigert, John, Carter, Kerri, Paul, William E., Watson, Cynthia, Tsang, Monica, Zhou, Li, Westreich, Louis, Chao, Chun C., Riss, Terry L., Moravec, Rich, Mire-Sluis, Anthony R., Das, Rose Gaines, Thorpe, Robin, Thomas, Sandra, Maher, Darryl, Valent, Peter, Payer, Elisabeth, De Groote, Groote, Hayglass, Kent, Ziltener, H., Poulsen, Lars K., Miossec, Pierre, Chomarat, P., Grassi, Jacques, Pawelec, G., Fritzsche, U., Reisbach, G., Sidiropoulos, John, Ben-Sasson, S. Z., Even-Chen, Zeev, Pegoraro, Luigi, Barboni, Francesco, Sugimoto, Kenkichi, Tsuji, K., Matsumoto, Tomoaki, Arai, Kenrichi, Yokota, Takashi, Olobo, J., Wagemaker, G., Van Der Pouw-Kraan, T., Sheth, Kirrikant V., Gutierrez, C., Rivas, D., Lyeke, Nils, Schön, Karin, Bews, John P.A., Tullberg, K., Klotzbücher, R., Page, L., Bird, C., McGuckin, Colin P., Gordon, John, Katira, Anita, Openshaw, Peter, Georgiou, Andrew, Testa, Nydia G., Callard, Robin, Paik, K., McKearn, John, Rock, Marie, Harper, Kathleen, Swanson, Steven J., Siegel, Jay P., Spiegelberg, H. L., Geigert, John, Carter, Kerri, Paul, William E., Watson, Cynthia, Tsang, Monica, Zhou, Li, Westreich, Louis, Chao, Chun C., Riss, Terry L., and Moravec, Rich

Abstract

Five ampouled preparations of interleukin-4 (IL-4) have been evaluated by 36 laboratories in 14 countries for their suitability to serve as an international standard for this material in a joint international collaborative study for interleukin-3 (IL-3) and IL-4. The preparations were assayed in a wide range of in vitro bioassays and immunoassays. It is clear from the study that different recombinant preparations of IL-4 can have very different biological specific activities, including those from the same source (i.e., E. coli). In addition, immunoassay estimates of IL-4 levels did not correlate with those of bioassays, illustrating the fact that immunoassays do not necessarily measure active cytokine. It is of interest that the estimates provided by the different bioassays were less variable than those produced by the immunoassays, suggesting that bioassays can be as accurate, if not more so, than immunoassays. The large reduction in the variability of estimates with the inclusion of a single reference preparation clearly illustrates the need for a single standard to assay IL-4. On the basis of the results reported here, with the agreement of the participants of the study with the authorization of the Expert Committee on Biological Standardization (ECBS) on the World Health Organization (WHO) the preparation of IL-4 (88/656) was established as the international standard for interleukin-4 with an assigned unitage of 1000 IU/ampoule.

Published
1996

32. Recombinant Human Albumin as a Stabilizer for Biological Materials and for the Preparation of International Reference Reagents

Author

Tarelli, Edward, primary, Mire-Sluis, Anthony, additional, Tivnann, Helen A., additional, Bolgiano, Barbara, additional, Crane, Dennis T., additional, Gee, Christopher, additional, Lemercinier, Xavier, additional, Athayde, Margareth L., additional, Sutcliffe, Nicholas, additional, Corran, Patrick H., additional, and Rafferty, Brian, additional

Published
1998
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