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3. What Has Been Done to Improve Learning for Intellectual Disability? An Umbrella Review of Published Meta-Analyses and Systematic Reviews

Author

Alvarenga, Kevin Augusto Farias, Alcântara, Wagner Lima, and Miranda, Débora Marques

Abstract

Background: Intellectual disability (ID) affects 1%-3% of the paediatric population. Currently, there is no consensus as to the most effective strategies for improving the learning skills of children and adolescents with ID. This review aims to systematically gather information regarding interventions to promote and improve learning skills in children/adolescents with ID from previously published systematic reviews and meta-analyses. Methods: Systematic search strategies, including appropriate descriptors, were employed on Medline, Cochrane, Scopus, Web of Science, Lilacs, SciELO, ERIC, and PsycINFO databases. Quality assessment was conducted via the AMSTAR-2. Results: Fifty-nine studies were selected, subdivided by outcome domains and by the type of intervention. Interventions were related to caregiving, education, pharmaco-dietary, physical, and technology approaches. The overall low quality of the studies limited our recommendations.

Published
2023
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4. Safety and efficacy of repetitive stimulation of the left dorsolateral prefrontal cortex using transcranial focused ultrasound in treatment-resistant depressed patients: A non-inferiority randomized controlled trial protocol

Author

dos Santos Alves Maria, Gustavo, Dias, Natália Silva, Nicolato, Rodrigo, de Paula, Jonas Jardim, Bicalho, Maria Aparecida Camargos, Cunha, Renan Souza, Silva, Luciana Costa, de Miranda, Débora Marques, de Mattos Viana, Bernardo, and Romano-Silva, Marco Aurélio

Published
2024
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7. Association between emotional stability and suicidality in a Brazilian sample of the general population during the COVID-19 pandemic and the moderation role of financial hardship

Author

Diaz, Alexandre Paim, Joaquim, Rui Mateus, Costa, Danielle de Souza, Pinto, André Luíz de Carvalho Braule, Serpa, Alexandre Luiz de Oliveira, Teles, Ana Luiza Silva, Guatimosim, Rafaela F., de Miranda, Débora Marques, da Silva, Antônio Geraldo, and Malloy-Diniz, Leandro Fernandes

Published
2024
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9. Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings

Author

de Paula, Jonas Jardim, Paiva, Rachel E. R. P., Souza-Silva, Nathália Gualberto, Rosa, Daniela Valadão, Duran, Fabio Luis de Souza, Coimbra, Roney Santos, Costa, Danielle de Souza, Dutenhefner, Pedro Robles, Oliveira, Henrique Soares Dutra, Camargos, Sarah Teixeira, Vasconcelos, Herika Martins Mendes, de Oliveira Carvalho, Nara, da Silva, Juliana Batista, Silveira, Marina Bicalho, Malamut, Carlos, Oliveira, Derick Matheus, Molinari, Luiz Carlos, de Oliveira, Danilo Bretas, Januário, José Nélio, Silva, Luciana Costa, De Marco, Luiz Armando, Queiroz, Dulciene Maria de Magalhaes, Meira, Wagner, Busatto, Geraldo, Miranda, Débora Marques, and Romano-Silva, Marco Aurélio

Published
2023
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13. Prevalence of congenital cytomegalovirus infection in preterm, small for gestational age and low birth weight newborns: characteristics and cytokines profile

Author

Lino, Janaina Fortes, Diniz, Lilian Martins Oliveira, de Miranda, Débora Marques, Rosa, Daniela Valadão Freitas, Silva, Nathália Gualberto Souza e, de Souza Nicolau, Eduardo, Rezende, Larissa Gonçalves, Carvalho, Lais Silva, de Paula Lopes, Marianna Fischer, Correa, Luísa Petri, de Oliveira, Gabriela Mafra, da Silva Alves, Flávia Miranda, Pascoal, Lorena Batista, da Costa, Érika Lima Dolabella Teixeira, Anchieta, Lêni Márcia, and de Castro Romanelli, Roberta Maia

Published
2022
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14. Are COMT Val158Met (rs4680), DRD2 TaqIA (rs1800497), and BDNF Val66Met (rs6265) polymorphisms associated with executive functions performance at rest and during physical exercise?

Author

Frois, Thais, Faria, Larissa Oliveira, Souza, Renan Pedra de, da Silva Cunha, Andressa Eliza, de Holanda Marinho Nogueira, Nathálya Gardênia, Tavares Lim, Vinicius, de Sousa Fortes, Leonardo, de Miranda, Débora Marques, Bertollo, Maurizio, and Albuquerque, Maicon Rodrigues

Published
2022
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15. Parental experiences of homeschooling during the COVID-19 pandemic: differences between seven European countries and between children with and without mental health conditions

Author

Thorell, Lisa B., Skoglund, Charlotte, de la Peña, Almudena Giménez, Baeyens, Dieter, Fuermaier, Anselm B. M., Groom, Madeleine J., Mammarella, Irene C., van der Oord, Saskia, van den Hoofdakker, Barbara J., Luman, Marjolein, de Miranda, Débora Marques, Siu, Angela F. Y., Steinmayr, Ricarda, Idrees, Iman, Soares, Lorrayne Stephane, Sörlin, Matilda, Luque, Juan Luis, Moscardino, Ughetta M., Roch, Maja, Crisci, Giulia, and Christiansen, Hanna

Published
2022
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16. Attention deficit and hyperactivity disorder and nocturnal enuresis co-occurrence in the pediatric population: a systematic review and meta-analysis

Author

de Sena Oliveira, Ana Cecília, Athanasio, Bruno da Silva, Mrad, Flávia Cristina de Carvalho, Vasconcelos, Monica Maria de Almeida, Albuquerque, Maicon Rodrigues, Miranda, Débora Marques, and Simões e Silva, Ana Cristina

Subjects
Enuresis -- Diagnosis -- Care and treatment -- Distribution, Attention-deficit hyperactivity disorder -- Diagnosis -- Care and treatment -- Distribution, Pediatric research, Company distribution practices, Health
Abstract

Background Attention deficit and hyperactivity/impulsivity disorder (ADHD) and enuresis are common behavioral disorders in childhood, impacting adolescence and adult life. Enuresis (NE) is an incontinence disorder frequently observed in children with ADHD. The relationship between ADHD and NE has been a matter of debate. Objectives We aimed to verify the relationship between ADHD and enuresis and how these conditions can modify each other during development. Using PRISMA guidelines, under the PROSPERO registration number CRD42020208299, we systematically searched the literature and conducted a meta-analysis to answer the following question: how frequent is ADHD and enuresis comorbidity? Twenty-five studies were fully read, and data from seven less heterogeneous case-control studies were pooled to estimate enuresis prevalence comparing ADHD and control samples, whereas six studies were combined to evaluate ADHD frequencies in children with and without enuresis. Results We found the ADHD rates in children with enuresis are similar to the enuresis rates in the group of children with ADHD. The presence of ADHD and enuresis comorbidity does not seem to play a role in gender distribution and the presence of other comorbidities in comparison to controls. However, enuresis seems to persist for more time in children with ADHD. Limitations The selected papers differed in study type, research question, samples, and controls utilized. Conclusions Our systematic review with meta-analysis supports the reciprocal association between enuresis and ADHD. Further studies are necessary to build more robust evidence., Author(s): Ana Cecília de Sena Oliveira [sup.1] , Bruno da Silva Athanasio [sup.1] , Flávia Cristina de Carvalho Mrad [sup.2] , Monica Maria de Almeida Vasconcelos [sup.2] , Maicon Rodrigues [...]

Published
2021
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17. Psychiatric disorders in individuals born very preterm / very low-birth weight: An individual participant data (IPD) meta-analysis

Author

Anderson, Peter J, de Miranda, Debora Marques, Albuquerque, Maicon Rodrigues, Indredavik, Marit Sæbø, Evensen, Kari Anne I., Van Lieshout, Ryan, Saigal, Saroj, Taylor, H. Gerry, Raikkonen, Katri, Kajantie, Eero, Marlow, Neil, Johnson, Samantha, Woodward, Lianne J., Austin, Nicola, Nosarti, Chiara, Jaekel, Julia, Wolke, Dieter, Cheong, Jeanie LY, Burnett, Alice, Treyvaud, Karli, Lee, Katherine J, and Doyle, Lex W

Published
2021
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23. Scales and quotient ADHD system properties: a correlation study

Author

Araújo, Maria Isabel Chaves, primary, Bragança, Bruna, additional, Moraes, Paulo Henrique Paiva de, additional, Paula, Jonas Jardim de, additional, Silva, Matheus Sewastjanow da, additional, Miranda, Débora Marques de, additional, and Malloy-Diniz, Leandro Fernandes, additional

Published
2023
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28. Decision-making styles during stressful scenarios: The role of anxiety in COVID-19 pandemic

Author

Marques da Rocha, Mariana Castro, primary, Malloy-Diniz, Leandro Fernandes, additional, Romano-Silva, Marco Aurélio, additional, Joaquim, Rui Mateus, additional, Serpa, Alexandre Luiz de Oliveira, additional, Paim Diaz, Alexandre, additional, de Paula, Jonas Jardim, additional, Costa, Danielle Souza, additional, Silva, Antônio Geraldo da, additional, Pinto, André Luiz de Carvalho Braule, additional, and de Miranda, Débora Marques, additional

Published
2023
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37. Longitudinal Profile of Post traumatic symptoms in HealthCare Workers during COVID-19 pandemic: A latent transition model

Author

Pinto, André Luiz Braule, primary, Serpa, Alexandre Luiz de Oliveira, additional, Guatimosim, Rafaela Ferreira, additional, de Souza Costa, Danielle, additional, de Paula, Jonas Jardim, additional, Silva, Antônio Geraldo, additional, Diaz, Alexandre Paim, additional, de Miranda, Débora Marques, additional, and Malloy-Diniz, Leandro, additional

Published
2022
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38. Aplicabilidade da versão brasileira da Multidimensional Scale for Invasive Developmental Disorder (MSPA-BR): explorando a sobreposição de TEA e TDAH

Author

Fernandes, Juliana Nassau, primary, Paula, Jonas Jardim, additional, Géo, Lucas Araújo Lima, additional, Costa Filho, Admilson Lemos, additional, Albuquerque, Maicon Rodrigues, additional, Funabiki, Yasuko, additional, Miranda, Débora Marques, additional, and Malloy-Diniz, Leandro Fernandes, additional

Published
2022
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43. Longitudinal invariance and validity of the Impact of Event Scale–Revised under COVID-19 pandemic in a Brazilian sample.

Author

Braule Pinto, André Luiz de Carvalho, primary, Guatimosim, Rafaela Ferreira, additional, Loureiro, Fabiano Franca, additional, Serpa, Alexandre Luiz de Oliveira, additional, Costa, Danielle Souza, additional, Diaz, Alexandre Paim, additional, Joaquim, Rui Mateus, additional, Baldaçara, Leonardo Rodrigo, additional, Alves Maria, Gustavo dos Santos, additional, da Silva, Antônio Geraldo, additional, de Miranda, Débora Marques, additional, and Malloy-Diniz, Leandro Fernandes, additional

Published
2022
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45. What has been done to improve learning for intellectual disability? An umbrella review of published meta‐analyses and systematic reviews.

Author

de Alvarenga, Kevin Augusto Farias, de Alcântara, Wagner Lima, and de Miranda, Débora Marques

Subjects
MEDICAL databases, PSYCHOLOGY information storage & retrieval systems, SYSTEMATIC reviews, LEARNING, ABILITY, TRAINING, AUTONOMY (Psychology), QUALITY of life, HEALTH care teams, RESEARCH funding, MEDLINE, SOCIODEMOGRAPHIC factors, INTELLECTUAL disabilities, MOTOR ability, SOCIAL integration
Abstract

Background: Intellectual disability (ID) affects 1%–3% of the paediatric population. Currently, there is no consensus as to the most effective strategies for improving the learning skills of children and adolescents with ID. This review aims to systematically gather information regarding interventions to promote and improve learning skills in children/adolescents with ID from previously published systematic reviews and meta‐analyses. Methods: Systematic search strategies, including appropriate descriptors, were employed on Medline, Cochrane, Scopus, Web of Science, Lilacs, SciELO, ERIC, and PsycINFO databases. Quality assessment was conducted via the AMSTAR‐2. Results: Fifty‐nine studies were selected, subdivided by outcome domains and by the type of intervention. Interventions were related to caregiving, education, pharmaco‐dietary, physical, and technology approaches. The overall low quality of the studies limited our recommendations. [ABSTRACT FROM AUTHOR]

Published
2023
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47. The Autism Spectrum Quotient in a sample of Brazilian adults: analyses of normative data and performance

Author

Alves, Ana Luíza Costa, Paula, Jonas Jardim de, Miranda, Débora Marques de, and Romano-Silva, Marco Aurélio

Subjects
Cross-Cultural Comparison, Transtorno do Espectro Autista, Autism Spectrum Disorder, Síndrome de Asperger, Comparação Transcultural, Asperger Syndrome
Abstract

Autism spectrum disorder (ASD) is characterized by difficulties in social interaction and inflexible behaviors/interests. To quantify ASD traits in adults with preserved intelligence, the Autism Spectrum Quotient (AQ) was developed, which is a self-report instrument and one of the most used and recommended tools. Objectives: We aimed to present a descriptive analysis of the AQ in a sample of Brazilian adults with neurotypical development (n=385) and investigate how the scale performs in a clinical subsample (n=33). Methods: We recruited 1,024 participants. They answered the Self-Reporting Questionnaire-20 (SRQ-20), AQ, and about their psychiatric record. Then, we selected 385 participants without any psychiatric diagnosis to describe the distribution of the ASD traits. To investigate the AQ performance, we evaluated 33 adults with ASD and 19 adults with neurotypical development from the total sample (n=1,024). Results: ASD traits were normally distributed in the population, with high internal consistency. Of a total of 91 men, volunteers with 32 points (clinical cutoff point) or more scored higher than 93% of the control sample. Of a total of 294 women, those who got a clinical score on the scale scored higher than 97%. In the clinical subsample (n=33), the positive predictive value (PPV) of the AQ was 0.84, and the negative predictive value (NPV) was 0.7. Conclusions: The study population has a different profile compared to the original study regarding the AQ scale. ASD traits were normally distributed in the neurotypical sample, and the scale seems to have a satisfactory performance to predict ASD. Future studies are required to adequate the use of the scale in the Brazilian population. RESUMO. O transtorno do espectro do autismo (TEA) é caracterizado por dificuldades na interação social e comportamentos/interesses inflexíveis. Com o intuito de quantificar os traços de TEA em adultos com inteligência preservada, foi desenvolvido o quociente do espectro do autismo (QA), um instrumento de autorrelato muito utilizado e recomendado. Objetivos: Nosso objetivo foi apresentar uma análise descritiva do QA em uma amostra de adultos brasileiros com desenvolvimento neurotípico (n=385) e investigar o desempenho da escala em uma subamostra clínica (n=33). Métodos: Foram recrutados 1.024 participantes, que responderam ao Self-Reporting Questionnaire-20 (SRQ-20), ao QA e a questões sobre o seu histórico psiquiátrico. Em seguida, selecionamos 385 participantes sem qualquer diagnóstico psiquiátrico para descrever a distribuição dos traços de TEA. Para investigar o desempenho do QA, avaliamos 33 adultos com TEA e 19 adultos com desenvolvimento neurotípico da amostra total (n=1024). Resultados: As características do TEA apresentaram distribuição normal na amostra, com alta consistência interna. Do total de 91 homens, os voluntários com 32 pontos (ponto de corte clínico) ou mais pontuaram acima de 93% da amostra de controle. De 294 mulheres, aquelas que obtiveram pontuação clínica na escala pontuaram acima de 97%. Na subamostra clínica (n=33), o valor preditivo positivo do QA foi de 0,84 e o valor preditivo negativo foi de 0,7. Conclusões: A população estudada apresenta um perfil diferente comparada à população do estudo original, no que se refere à escala QA. Os traços de TEA foram normalmente distribuídos na amostra neurotípica, e a escala parece ter um desempenho satisfatório para predizer autismo. Estudos futuros são necessários para adequar o uso da escala na população brasileira.

Published
2022

48. Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings

Author

de Paula, Jonas Jardim, primary, Paiva, Rachel E. R. P., additional, Souza-Silva, Nathália Gualberto, additional, Rosa, Daniela Valadão, additional, Duran, Fabio Luis de Souza, additional, Coimbra, Roney Santos, additional, Costa, Danielle de Souza, additional, Dutenhefner, Pedro Robles, additional, Oliveira, Henrique Soares Dutra, additional, Camargos, Sarah Teixeira, additional, Vasconcelos, Herika Martins Mendes, additional, de Oliveira Carvalho, Nara, additional, da Silva, Juliana Batista, additional, Silveira, Marina Bicalho, additional, Malamut, Carlos, additional, Oliveira, Derick Matheus, additional, Molinari, Luiz Carlos, additional, de Oliveira, Danilo Bretas, additional, Januário, José Nélio, additional, Silva, Luciana Costa, additional, De Marco, Luiz Armando, additional, Queiroz, Dulciene Maria de Magalhaes, additional, Meira, Wagner, additional, Busatto, Geraldo, additional, Miranda, Débora Marques, additional, and Romano-Silva, Marco Aurélio, additional

Published
2022
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50. O QUOCIENTE DO ESPECTRO DO AUTISMO EM UMA AMOSTRA DE ADULTOS BRASILEIROS: ANÁLISES DE DADOS NORMATIVOS E DE DESEMPENHO

Author

Alves, Ana Luíza Costa, Paula, Jonas Jardim de, Miranda, Débora Marques de, and Romano-Silva, Marco Aurélio

Subjects
Cross-Cultural Comparison, Autism Spectrum Disorder, Transtorno do Espectro Autista, Síndrome de Asperger, Asperger Syndrome, Comparação Transcultural
Abstract

Autism spectrum disorder (ASD) is characterized by difficulties in social interaction and inflexible behaviors/interests. To quantify ASD traits in adults with preserved intelligence, the Autism Spectrum Quotient (AQ) was developed, which is a self-report instrument and one of the most used and recommended tools. Objectives: We aimed to present a descriptive analysis of the AQ in a sample of Brazilian adults with neurotypical development (n=385) and investigate how the scale performs in a clinical subsample (n=33). Methods: We recruited 1,024 participants. They answered the Self-Reporting Questionnaire-20 (SRQ-20), AQ, and about their psychiatric record. Then, we selected 385 participants without any psychiatric diagnosis to describe the distribution of the ASD traits. To investigate the AQ performance, we evaluated 33 adults with ASD and 19 adults with neurotypical development from the total sample (n=1,024). Results: ASD traits were normally distributed in the population, with high internal consistency. Of a total of 91 men, volunteers with 32 points (clinical cutoff point) or more scored higher than 93% of the control sample. Of a total of 294 women, those who got a clinical score on the scale scored higher than 97%. In the clinical subsample (n=33), the positive predictive value (PPV) of the AQ was 0.84, and the negative predictive value (NPV) was 0.7. Conclusions: The study population has a different profile compared to the original study regarding the AQ scale. ASD traits were normally distributed in the neurotypical sample, and the scale seems to have a satisfactory performance to predict ASD. Future studies are required to adequate the use of the scale in the Brazilian population. RESUMO. O transtorno do espectro do autismo (TEA) é caracterizado por dificuldades na interação social e comportamentos/interesses inflexíveis. Com o intuito de quantificar os traços de TEA em adultos com inteligência preservada, foi desenvolvido o quociente do espectro do autismo (QA), um instrumento de autorrelato muito utilizado e recomendado. Objetivos: Nosso objetivo foi apresentar uma análise descritiva do QA em uma amostra de adultos brasileiros com desenvolvimento neurotípico (n=385) e investigar o desempenho da escala em uma subamostra clínica (n=33). Métodos: Foram recrutados 1.024 participantes, que responderam ao Self-Reporting Questionnaire-20 (SRQ-20), ao QA e a questões sobre o seu histórico psiquiátrico. Em seguida, selecionamos 385 participantes sem qualquer diagnóstico psiquiátrico para descrever a distribuição dos traços de TEA. Para investigar o desempenho do QA, avaliamos 33 adultos com TEA e 19 adultos com desenvolvimento neurotípico da amostra total (n=1024). Resultados: As características do TEA apresentaram distribuição normal na amostra, com alta consistência interna. Do total de 91 homens, os voluntários com 32 pontos (ponto de corte clínico) ou mais pontuaram acima de 93% da amostra de controle. De 294 mulheres, aquelas que obtiveram pontuação clínica na escala pontuaram acima de 97%. Na subamostra clínica (n=33), o valor preditivo positivo do QA foi de 0,84 e o valor preditivo negativo foi de 0,7. Conclusões: A população estudada apresenta um perfil diferente comparada à população do estudo original, no que se refere à escala QA. Os traços de TEA foram normalmente distribuídos na amostra neurotípica, e a escala parece ter um desempenho satisfatório para predizer autismo. Estudos futuros são necessários para adequar o uso da escala na população brasileira.

Published
2022

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