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Your search keyword '"Minicuci, Giacomo"' showing total 16 results
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16 results on '"Minicuci, Giacomo"'

4. Unclassified clinical presentations of chronic inflammatory demyelinating polyradiculoneuropathy

Author

Doneddu, Pietro Emiliano, primary, Akyil, Houseyin, additional, Manganelli, Fiore, additional, Briani, Chiara, additional, Cocito, Dario, additional, Benedetti, Luana, additional, Mazzeo, Anna, additional, Fazio, Raffaella, additional, Filosto, Massimiliano, additional, Cosentino, Giuseppe, additional, Di Stefano, Vincenzo, additional, Antonini, Giovanni, additional, Marfia, Girolama Alessandra, additional, Inghilleri, Maurizio, additional, Siciliano, Gabriele, additional, Clerici, Angelo Maurizio, additional, Carpo, Marinella, additional, Schenone, Angelo, additional, Luigetti, Marco, additional, Lauria, Giuseppe, additional, Matà, Sabrina, additional, Rosso, Tiziana, additional, Minicuci, Giacomo Maria, additional, Lucchetta, Marta, additional, Cavaletti, Guido, additional, Liberatore, Giuseppe, additional, Spina, Emanuele, additional, Campagnolo, Marta, additional, Peci, Erdita, additional, Germano, Francesco, additional, Gentile, Luca, additional, Strano, Camilla, additional, Cotti Piccinelli, Stefano, additional, Vegezzi, Elisa, additional, Leonardi, Luca, additional, Mataluni, Giorgia, additional, Ceccanti, Marco, additional, Schirinzi, Erika, additional, Romozzi, Marina, additional, and Nobile-Orazio, Eduardo, additional

Published
2023
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5. Italian version of the Rasch-Built Overall Amyotrophic Lateral Sclerosis Disability Scale (ROADS): validation and longitudinal performance

Author

Fortuna, Andrea, primary, Sabbatini, Daniele, additional, Frigo, Annachiara, additional, Bello, Luca, additional, Calvi, Francesca, additional, Blasi, Lorenzo, additional, Gianferrari, Giulia, additional, Martinelli, Ilaria, additional, Minicuci, Giacomo, additional, Pegoraro, Elena, additional, Mandrioli, Jessica, additional, and Sorarù, Gianni, additional

Published
2022
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12. Response to therapy in myasthenia gravis with anti-MuSK antibody

Author

Evoli Stampanoni-B, Amelia, Bianchi, M, Riso, R, Minicuci, Giacomo Maria, Batocchi, Anna Paola, Servidei, Serenella, Scuderi, Flavia, Bartoccioni, Emanuela, Evoli, Amelia (ORCID:0000-0003-0282-8787), Servidei, Serenella (ORCID:0000-0001-8478-2799), Bartoccioni, Emanuela (ORCID:0000-0002-4434-8661), Evoli Stampanoni-B, Amelia, Bianchi, M, Riso, R, Minicuci, Giacomo Maria, Batocchi, Anna Paola, Servidei, Serenella, Scuderi, Flavia, Bartoccioni, Emanuela, Evoli, Amelia (ORCID:0000-0003-0282-8787), Servidei, Serenella (ORCID:0000-0001-8478-2799), and Bartoccioni, Emanuela (ORCID:0000-0002-4434-8661)

Abstract

Myasthenia gravis (MG) with antibodies against the muscle-specific tyrosine kinase (MuSK abs) is often a severe disease requiring aggressive treatment. Various immunosuppressive (IS) regimens have been employed; the efficacy of plasma exchange is unanimously recognized, while the indication for thymectomy is controversial. We evaluated the response to therapy in 57 MuSK-positive patients (12 M/45 F) comparing our experience with other authors' results. Disease severity and response to treatment were graded according to MG Foundation of America; follow-up ranged from 0.5-29 years. Owing to both MG severity and the unsatisfactory response to cholinesterase inhibitors, most patients (54/57) needed IS treatment, and 35 received one or more courses of plasma exchange and intravenous immunoglobulin. At the end of follow-up, the rate of complete remission was 8.8%, and IS treatment had been withdrawn in only 10/54 patients. The extent of therapeutic response varied considerably. With conventional IS therapy (prednisone alone or in combination with azathioprine or cyclosporine), most patients achieved good control of their disease, but 30% of them were left with permanent facial and bulbar weakness. In patients with refractory disease, the use of mycophenolate mofetil and rituximab proved very effective, as also reported by other authors. In our and others' experience, MuSK-positive MG markedly improves with IS therapy, although, in comparison with the AChR-positive disease, it is characterized by a lower remission rate, as a higher proportion of patients remain dependent on treatment. Thymectomy is mostly considered scarcely effective; however, at present, no firm conclusions can be drawn on its role in the treatment of this form of MG.

Published
2008

13. Anti-MuSK antibodies: Correlation with myasthenia gravis severity

Author

Bartoccioni, Emanuela, Scuderi, Flavia, Minicuci, Giacomo Maria, Marino, Mariapaola, Ciaraffa, F., Evoli Stampanoni-B, Amelia, Bartoccioni E. (ORCID:0000-0002-4434-8661), Scuderi F., Minicuci G. M., Marino M. (ORCID:0000-0001-9155-6378), Evoli A. (ORCID:0000-0003-0282-8787), Bartoccioni, Emanuela, Scuderi, Flavia, Minicuci, Giacomo Maria, Marino, Mariapaola, Ciaraffa, F., Evoli Stampanoni-B, Amelia, Bartoccioni E. (ORCID:0000-0002-4434-8661), Scuderi F., Minicuci G. M., Marino M. (ORCID:0000-0001-9155-6378), and Evoli A. (ORCID:0000-0003-0282-8787)

Abstract

The authors measured anti–muscle-specific tyrosine kinase (anti- MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.

Published
2006

14. P065 Modulating cortical excitability in acute stroke: a repetitive TMS study

Author

Dileone, Michele, primary, Pilato, Fabio, additional, Profice, Paolo, additional, Capone, Fioravante, additional, Ranieri, Federico, additional, Musumeci, Gabriella, additional, Cianfoni, Alessandro, additional, Pasqualetti, Patrizio, additional, Florio, Lucia, additional, Tagliente, Daniela, additional, Minicuci, Giacomo, additional, Iorio, Riccardo Di, additional, Tonali, Pietro Attilio, additional, and Lazzaro, Vincenzo Di, additional

Published
2008
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15. P232 Functional evaluation of cerebral cortex in dementia with Lewy bodies

Author

Ranieri, Federico, primary, Pilato, Fabio, additional, Dileone, Michele, additional, Saturno, Eleonora, additional, Profice, Paolo, additional, Marra, Camillo, additional, Daniele, Antonio, additional, Quaranta, Davide, additional, Capone, Fioravante, additional, Florio, Lucia, additional, Tagliente, Daniela, additional, Iorio, Riccardo Di, additional, MInicuci, Giacomo, additional, Musumeci, Gabriella, additional, Gainotti, Guido, additional, Tonali, Pietro Attilio, additional, and Lazzaro, Vincenzo Di, additional

Published
2008
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