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3,992 results on '"Mingrone, A"'

1. Radiative neutron capture cross section of $^{242}$Pu measured at n_TOF-EAR1 in the unresolved resonance region up to 600 keV

Author

Lerendegui-Marco, J., Guerrero, C., Mendoza, E., Quesada, J. M., Eberhardt, K., Junghans, A. R., Alcayne, V., Babiano, V., Aberle, O., Andrzejewski, J., Audouin, L., Becares, V., Bacak, M., Balibrea-Correa, J., Barbagallo, M., Barros, S., Becvar, F., Beinrucker, C., Berthoumieux, E., Billowes, J., Bosnar, D., Brugger, M., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Castelluccio, D. M., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Damone, L. A., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A., Ferreira, P., Finocchiaro, P., Furman, V., Göbel, K., García, A. R., Gawlik, A., Glodariu, T., Goncalves, I. F., González-Romero, E., Goverdovski, A., Griesmayer, E., Gunsing, F., Harada, H., Heftrich, T., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Katabuchi, T., Kavrigin, P., Ketlerov, V., Khryachkov, V., Kimura, A., Kivel, N., Kokkoris, M., Krticka, M., Leal-Cidoncha, E., Lederer-Woods, C., Leeb, H., Meo, S. Lo, Lonsdale, S. J., Losito, R., Macina, D., Marganiec, J., Martínez, T., Massimi, C., Mastinu, P., Mastromarco, M., Matteucci, F., Maugeri, E. A., Mengoni, A., Milazzo, P. M., Mingrone, F., Mirea, M., Montesano, S., Musumarra, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Porras, J. I., Praena, J., Rajeev, K., Rauscher, T., Reifarth, R., Riego-Perez, A., Rout, P. C., Rubbia, C., Ryan, J. A., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schmidt, S., Schumann, D., Sedyshev, P., Smith, A. G., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Tsinganis, A., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weigand, M., Weiss, C., Wolf, C., Woods, P. J., Wright, T., Zugec, P., and Collaboration, the n_TOF

Subjects
Nuclear Experiment
Abstract

The design of fast reactors burning MOX fuels requires accurate capture and fission cross sections. For the particular case of neutron capture on 242Pu, the NEA recommends that an accuracy of 8-12% should be achieved in the fast energy region (2 keV-500 keV) compared to their estimation of 35% for the current uncertainty. Integral irradiation experiments suggest that the evaluated cross section of the JEFF-3.1 library overestimates the 242Pu(n,{\gamma}) cross section by 14% in the range between 1 keV and 1 MeV. In addition, the last measurement at LANSCE reported a systematic reduction of 20-30% in the 1-40 keV range relative to the evaluated libraries and previous data sets. In the present work this cross section has been determined up to 600 keV in order to solve the mentioned discrepancies. A 242Pu target of 95(4) mg enriched to 99.959% was irradiated at the n TOF-EAR1 facility at CERN. The capture cross section of 242Pu has been obtained between 1 and 600 keV with a systematic uncertainty (dominated by background subtraction) between 8 and 12%, reducing the current uncertainties of 35% and achieving the accuracy requested by the NEA in a large energy range. The shape of the cross section has been analyzed in terms of average resonance parameters using the FITACS code as implemented in SAMMY, yielding results compatible with our recent analysis of the resolved resonance region.The results are in good agreement with the data of Wisshak and K\"appeler and on average 10-14% below JEFF-3.2 from 1 to 250 keV, which helps to achieve consistency between integral experiments and cross section data. At higher energies our results show a reasonable agreement within uncertainties with both ENDF/B-VII.1 and JEFF-3.2. Our results indicate that the last experiment from DANCE underestimates the capture cross section of 242Pu by as much as 40% above a few keV., Comment: 20 pages, 19 figures, submitted to Phys. Rev. C

Published
2024

2. Measurement and analysis of the $^{246}$Cm and $^{248}$Cm neutron capture cross-sections at the EAR2 of the n TOF facility

Author

Alcayne, V., Kimura, A., Mendoza, E., Cano-Ott, D., Aberle, O., Álvarez-Velarde, F., Amaducci, S., Andrzejewski, J., Audouin, L., Bécares, V., Babiano-Suarez, V., Bacak, M., Barbagallo, M., Bečvář, F., Bellia, G., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Busso, M., Caamaño, M., Caballero-Ontanaya, L., Calviño, F., Calviani, M., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fernández-Domınguez, B., Ferrari, A., Finocchiaro, P., Furman, V., Göbel, K., Garg, R., Gawlik-Ramiega, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kivel, N., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Ladarescu, I., Lederer-Woods, C., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Macina, D., Manna, A., Martınez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Matteucci, F., Maugeri, E. A., Mazzone, A., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., de Rada, A. Pérez, Perkowski, J., Persanti, L., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Ramos-Doval, D., Rauscher, T., Reifarth, R., Rochman, D., Romanets, Y., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Talip, T., Tarifeño-Saldivia, A., Tassan-Got, L., Torres-Sánchez, P., Tsinganis, A., Ulrich, J., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Nuclear Experiment
Abstract

The $^{246}$Cm(n,$\gamma$) and $^{248}$Cm(n,$\gamma$) cross-sections have been measured at the Experimental Area 2 (EAR2) of the n_TOF facility at CERN with three C$_6$D$_6$ detectors. This measurement is part of a collective effort to improve the capture cross-section data for Minor Actinides (MAs), which are required to estimate the production and transmutation rates of these isotopes in light water reactors and innovative reactor systems. In particular, the neutron capture in $^{246}$Cm and $^{248}$Cm open the path for the formation of other Cm isotopes and heavier elements such as Bk and Cf and the knowledge of (n,$\gamma$) cross-sections of these Cm isotopes plays an important role in the transport, transmutation and storage of the spent nuclear fuel. The reactions $^{246}$Cm(n,$\gamma$) and $^{248}$Cm(n,$\gamma$) have been the two first capture measurements analyzed at n_TOF EAR2. Until this experiment and two recent measurements performed at J-PARC, there was only one set of data of the capture cross-sections of $^{246}$Cm and $^{248}$Cm, that was obtained in 1969 in an underground nuclear explosion experiment. In the measurement at n_TOF a total of 13 resonances of $^{246}$Cm between 4 and 400 eV and 5 of $^{248}$Cm between 7 and 100 eV have been identified and fitted. The radiative kernels obtained for $^{246}$Cm are compatible with JENDL-5, but some of them are not with JENDL-4, which has been adopted by JEFF-3.3 and ENDF/B-VIII.0. The radiative kernels obtained for the first three $^{248}$Cm resonances are compatible with JENDL-5, however, the other two are not compatible with any other evaluation and are 20% and 60% larger than JENDL-5.

Published
2024
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5. Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study

Author

Saux, Patrick, Bauvin, Pierre, Raverdy, Violeta, Teigny, Julien, Verkindt, Hélène, Soumphonphakdy, Tomy, Debert, Maxence, Jacobs, Anne, Jacobs, Daan, Monpellier, Valerie, Lee, Phong Ching, Lim, Chin Hong, Andersson-Assarsson, Johanna C, Carlsson, Lena, Svensson, Per-Arne, Galtier, Florence, Dezfoulian, Guelareh, Moldovanu, Mihaela, Andrieux, Severine, Couster, Julien, Lepage, Marie, Lembo, Erminia, Verrastro, Ornella, Robert, Maud, Salminen, Paulina, Mingrone, Geltrude, Peterli, Ralph, Cohen, Ricardo V, Zerrweck, Carlos, Nocca, David, Roux, Carel W Le, Caiazzo, Robert, Preux, Philippe, and Pattou, François

Subjects
Computer Science - Machine Learning, Statistics - Applications
Abstract

Background Weight loss trajectories after bariatric surgery vary widely between individuals, and predicting weight loss before the operation remains challenging. We aimed to develop a model using machine learning to provide individual preoperative prediction of 5-year weight loss trajectories after surgery. Methods In this multinational retrospective observational study we enrolled adult participants (aged $\ge$18 years) from ten prospective cohorts (including ABOS [NCT01129297], BAREVAL [NCT02310178], the Swedish Obese Subjects study, and a large cohort from the Dutch Obesity Clinic [Nederlandse Obesitas Kliniek]) and two randomised trials (SleevePass [NCT00793143] and SM-BOSS [NCT00356213]) in Europe, the Americas, and Asia, with a 5 year followup after Roux-en-Y gastric bypass, sleeve gastrectomy, or gastric band. Patients with a previous history of bariatric surgery or large delays between scheduled and actual visits were excluded. The training cohort comprised patients from two centres in France (ABOS and BAREVAL). The primary outcome was BMI at 5 years. A model was developed using least absolute shrinkage and selection operator to select variables and the classification and regression trees algorithm to build interpretable regression trees. The performances of the model were assessed through the median absolute deviation (MAD) and root mean squared error (RMSE) of BMI. Findings10 231 patients from 12 centres in ten countries were included in the analysis, corresponding to 30 602 patient-years. Among participants in all 12 cohorts, 7701 (75$\bullet$3%) were female, 2530 (24$\bullet$7%) were male. Among 434 baseline attributes available in the training cohort, seven variables were selected: height, weight, intervention type, age, diabetes status, diabetes duration, and smoking status. At 5 years, across external testing cohorts the overall mean MAD BMI was 2$\bullet$8 kg/m${}^2$ (95% CI 2$\bullet$6-3$\bullet$0) and mean RMSE BMI was 4$\bullet$7 kg/m${}^2$ (4$\bullet$4-5$\bullet$0), and the mean difference between predicted and observed BMI was-0$\bullet$3 kg/m${}^2$ (SD 4$\bullet$7). This model is incorporated in an easy to use and interpretable web-based prediction tool to help inform clinical decision before surgery. InterpretationWe developed a machine learning-based model, which is internationally validated, for predicting individual 5-year weight loss trajectories after three common bariatric interventions., Comment: The Lancet Digital Health, 2023

Published
2023
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6. First Indicator of Relapse in Testicular Cancer and Implications for Follow-up: Analysis of the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS)

Author

Stefanie Fischer, Silke Gillessen, Odile Stalder, Angelika Terbuch, Richard Cathomas, Florian A. Schmid, Deborah Zihler, Beat Müller, Christian D. Fankhauser, Anita Hirschi-Blickenstorfer, Luis Alex Kluth, Bettina Seifert, Arnoud J. Templeton, Walter Mingrone, Mark-Peter Ufe, Natalie Fischer, Jörg Beyer, Regina Woelky, Aurelius Omlin, Ursula Vogl, Katharina Hoppe, Jörn Kamradt, Sacha I. Rothschild, and Christian Rothermundt

Subjects
Testicular cancer, Follow-up, Germ cell tumours, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background and objective: Follow-up for patients with testicular cancer should ensure early detection of relapses. Optimal schedules and minimum requirements for cross-sectional imaging are not clearly defined, and guideline recommendations differ. Our aim was to analyse the clinical impact of different imaging modalities for detection of relapse in a large prospective cohort (Swiss Austrian German Testicular Cancer Cohort Study, SAG TCCS). Methods: Patients with seminoma or nonseminoma were prospectively enrolled between January 2014 and February 2023 after initial treatment (n = 1175). Follow-up according to the study schedule was individualised for histology and disease stage. Only patients who had received primary treatment were considered. We analysed the total number of imaging modalities and scans identifying relapse and the timing of relapse. Key findings and limitations: We analysed data for 1006 patients (64% seminoma, 36% nonseminoma); 76% had stage I disease. Active surveillance was the most frequent management strategy (65%). Recurrence occurred in 82 patients, corresponding to a 5-yr relapse-free survival rate of 90.1% (95% confidence interval 87.7–92.1%). Median follow-up for patients without relapse was 38.4 mo (interquartile range 21.6–61.0). Cross-sectional imaging of the abdomen was the most important indicator of relapse 57%, abdominal CT accounting for 46% and MRI for 11%. Marker elevation indicated relapse in 24% of cases. Chest X-ray was the least useful modality, indicating relapse in just 2% of cases. Conclusions and clinical implications: On the basis of findings from our prospective register, we have adapted follow-up schedules with an emphasis on abdominal imaging and a reduction in chest X-rays. These schedules might provide additional guidance for clinicians and will be prospectively evaluated as SAG TCCS continues to enrol patients. Patient summary: We analysed the value of different types of imaging scans for detection of relapse of testicular cancer. We used our findings to propose an optimum follow-up schedule for patients with testicular cancer.

Published
2024
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8. New insights on fission of 235U induced by high energy neutrons from a new measurement at n_TOF

Author

A. Manna, E. Pirovano, P. Console Camprini, L. Cosentino, M. Dietz, Q. Ducasse, P. Finocchiaro, C. Le Naour, D. Mancusi, C. Massimi, A. Mengoni, R. Nolte, D. Radeck, L. Tassan-Got, N. Terranova, G. Vannini, A. Ventura, O. Aberle, V. Alcayne, S. Amaducci, J. Andrzejewski, L. Audouin, V. Babiano-Suarez, M. Bacak, M. Barbagallo, S. Bennett, E. Berthoumieux, J. Billowes, D. Bosnar, A. Brown, M. Busso, M. Caamaño, L. Caballero-Ontanaya, F. Calviño, M. Calviani, D. Cano-Ott, A. Casanovas, D.M. Castelluccio, F. Cerutti, E. Chiaveri, N. Colonna, G. Cortés, M.A. Cortés-Giraldo, S. Cristallo, L.A. Damone, P.J. Davies, M. Diakaki, C. Domingo-Pardo, R. Dressler, E. Dupont, I. Durán, Z. Eleme, B. Fernández-Domínguez, A. Ferrari, V. Furman, K. Göbel, R. Garg, A. Gawlik-Ramięga, S. Gilardoni, I.F. Gonçalves, E. González-Romero, C. Guerrero, F. Gunsing, H. Harada, S. Heinitz, J. Heyse, D.G. Jenkins, A. Junghans, F. Käppeler, Y. Kadi, A. Kimura, I. Knapová, M. Kokkoris, Y. Kopatch, M. Krtička, D. Kurtulgil, I. Ladarescu, C. Lederer-Woods, H. Leeb, J. Lerendegui-Marco, S.J. Lonsdale, D. Macina, T. Martínez, A. Masi, P. Mastinu, M. Mastromarco, E.A. Maugeri, A. Mazzone, E. Mendoza, V. Michalopoulou, P.M. Milazzo, F. Mingrone, J. Moreno-Soto, A. Musumarra, A. Negret, F. Ogállar, A. Oprea, N. Patronis, A. Pavlik, J. Perkowski, C. Petrone, L. Piersanti, I. Porras, J. Praena, J.M. Quesada, D. Ramos-Doval, T. Rauscher, R. Reifarth, D. Rochman, C. Rubbia, M. Sabaté-Gilarte, A. Saxena, P. Schillebeeckx, D. Schumann, A. Sekhar, A.G. Smith, N.V. Sosnin, P. Sprung, A. Stamatopoulos, G. Tagliente, J.L. Tain, A. Tarifeño-Saldivia, Th. Thomas, P. Torres-Sánchez, A. Tsinganis, J. Ulrich, S. Urlass, S. Valenta, V. Variale, P. Vaz, D. Vescovi, V. Vlachoudis, R. Vlastou, A. Wallner, P.J. Woods, T. Wright, and P. Žugec

Subjects
Nuclear reaction, Neutron-induced reaction, n_TOF, High energy, Fission process, Cross section measurement, Physics, QC1-999
Abstract

The 235U(n, f) reaction cross section was measured relative to neutron-proton elastic scattering for the first time in the energy region from 10 MeV to 440 MeV at the CERN n_TOF facility, extending the upper limit of the only previous measurement in the literature by more than 200 MeV. For neutron energies below 200 MeV, our results agree within one standard deviation with data in literature. Above 200 MeV, the comparison of model calculations to our data indicates the need to introduce a transient time in neutron-induced fission to allow the simultaneous description of (n, f) and (p, f) reactions.

Published
2025
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9. Measurement of the $^{14}$N(n,p)$^{14}$C cross section at the CERN n_TOF facility from sub-thermal energy to 800 keV

Author

Torres-Sánchez, P., Praena, J., Porras, I., Sabaté-Gilarte, M., Lederer-Woods, C., Aberle, O., Alcayne, V., Amaducci, S., Andrzejewski, J., Audouin, L., Bécares, V., Babiano-Suarez, V., Bacak, M., Barbagallo, M., Bečvář, F., Bellia, G., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Busso, M., Caamaño, M., Caballero, L., Calviño, F., Calviani, M., Cano-Ott, D., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fernández-Domínguez, B., Ferrari, A., Ferrer, F. J., Finocchiaro, P., Furman, V., Göbel, K., Garg, R., Gawlik-Ramięga, A., Geslot, B., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kimura, A., Kivel, N., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Ladarescu, I., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Macina, D., Manna, A., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Matteucci, F., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Piersanti, L., Quesada, J. M., Radeck, D., Ramos-Doval, D., Rauscher, T., Reifarth, R., Rochman, D., Rubbia, C., Saxena, A., Schillebeeckx, P., Schumann, D., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Talip, T., Tarifeño-Saldivia, A., Tassan-Got, L., Tsinganis, A., Ulrich, J., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Nuclear Experiment
Abstract

Background: The $^{14}$N(n,p)$^{14}$C reaction is of interest in neutron capture therapy, where nitrogen-related dose is the main component due to low-energy neutrons, and in astrophysics, where 14N acts as a neutron poison in the s-process. Several discrepancies remain between the existing data obtained in partial energy ranges: thermal energy, keV region and resonance region. Purpose: Measuring the 14N(n,p)14C cross section from thermal to the resonance region in a single measurement for the first time, including characterization of the first resonances, and providing calculations of Maxwellian averaged cross sections (MACS). Method: Time-of-flight technique. Experimental Area 2 (EAR-2) of the neutron time-of-flight (n_TOF) facility at CERN. $^{10}$B(n,${\alpha}$)$^7$Li and $^{235}$U(n,f) reactions as references. Two detection systems running simultaneously, one on-beam and another off-beam. Description of the resonances with the R-matrix code sammy. Results: The cross section has been measured from sub-thermal energy to 800 keV resolving the two first resonances (at 492.7 and 644 keV). A thermal cross-section (1.809$\pm$0.045 b) lower than the two most recent measurements by slightly more than one standard deviation, but in line with the ENDF/B-VIII.0 and JEFF-3.3 evaluations has been obtained. A 1/v energy dependence of the cross section has been confirmed up to tens of keV neutron energy. The low energy tail of the first resonance at 492.7 keV is lower than suggested by evaluated values, while the overall resonance strength agrees with evaluations. Conclusions: Our measurement has allowed to determine the $^{14}$N(n,p) cross-section over a wide energy range for the first time. We have obtained cross-sections with high accuracy (2.5 %) from sub-thermal energy to 800 keV and used these data to calculate the MACS for kT = 5 to kT = 100 keV., Comment: 18 pages, 15 figures, 4 tables

Published
2022
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10. Recoil Proton Telescopes and Parallel Plate Avalanche Counters for the $^{235}$U(n,f) cross section measurement relative to H(n,n)H between 10 and 450 MeV neutron energy

Author

Manna, A., Pirovano, E., Aberle, O., Amaducci, S., Barbagallo, M., Castelluccio, D. M., Colonna, N., Camprini, P. Console, Cosentino, L., Dietz, M., Ducasse, Q., Finocchiaro, P., Naour, C. Le, Meo, S. Lo, Mastromarco, M., Massimi, C., Mengoni, A., Milazzo, P. M., Mingrone, F., Nolte, R., Piscopo, M., Radeck, D., Spelta, M., Tassan-Got, L., Terranova, N., and Vannini, G.

Subjects
Nuclear Experiment, Physics - Instrumentation and Detectors
Abstract

With the aim of measuring the $^{235}$U(n,f) cross section at the n\_TOF facility at CERN over a wide neutron energy range, a detection system consisting of two fission detectors and three detectors for neutron flux determination was realized. The neutron flux detectors are Recoil Proton Telescopes (RPT), based on scintillators and solid state detectors, conceived to detect recoil protons from the neutron-proton elastic scattering reaction. This system, along with a fission chamber and an array of parallel plate avalanche counters for fission event detection, was installed for the measurement at the n\_TOF facility in 2018, at CERN. An overview of the performances of two RPTs - especially developed for this measurement - and of the parallel plate avalanche counters are described in this article. In particular, the characterization in terms of detection efficiency by Monte Carlo simulations and response to neutron beam, the study of the background, dead time correction and characterization of the samples, are reported. The results of the present investigation show that the performances of these detectors are suitable for accurate measurements of fission reaction cross sections in the range from 10 to 450~MeV.

Published
2022
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11. Omission of Radiotherapy in Primary Mediastinal B-Cell Lymphoma: IELSG37 Trial Results

Author

Martelli, Maurizio, Ceriani, Luca, Ciccone, Giovannino, Ricardi, Umberto, Kriachok, Iryna, Botto, Barbara, Balzarotti, Monica, Tucci, Alessandra, Usai, Sara Veronica, Zilioli, Vittorio Ruggero, Pennese, Elsa, Arcaini, Luca, Dabrowska-Iwanicka, Anna, Ferreri, Andrés J.M., Merli, Francesco, Zhao, Weili, Rigacci, Luigi, Cellini, Claudia, Hodgson, David, Ionescu, Codruta, Minoia, Carla, Lucchini, Elisa, Spina, Michele, Fosså, Alexander, Janikova, Andrea, Cwynarski, Kate, Mikhaeel, George, Jerkeman, Mats, Di Rocco, Alice, Stepanishyna, Yana, Vitolo, Umberto, Santoro, Armando, Re, Alessandro, Puccini, Benedetta, Olivieri, Jacopo, Petrucci, Luigi, Barrington, Sally F., Malkowski, Bogdan, Metser, Ur, Versari, Annibale, Chauvie, Stephane, Walewski, Jan, Trneny, Marek, Cavalli, Franco, Gospodarowicz, Mary, Johnson, Peter W.M., Davies, Andrew, Zucca, Emanuele, Gospodarowicz, Mary, Hodgson, David, Kuruvilla, John, Wang, Li, Zhao, Weili, Balada, David, Huettmann, Andreas, Angrilli, Francesco, Annibali, Ombretta, Arcaini, Luca, Bagni, Oreste, Balzarotti, Monica, Battistini, Roberta, Botto, Barbara, Cabras, Maria Giuseppina, Calimeri, Teresa, Catello, Califano, Cavallo, Federica, Cellini, Claudia, Ciammella, Patrizia, Consoli, Ugo, De Sanctis, Vitaliana, Di Renzo, Nicola, Di Rocco, Alice, Fabbri, Alberto, Ferrari, Angela, Ferreri, Andrés J.M., Flenghi, Leonardo, Gaidano, Gianluca, Gini, Guido, Gotti, Manuel, Guarini, Attilio, Liberati, Anna Marina, Lucchini, Elisa, Mannina, Donato, Martelli, Maurizio, Matrone, Fabio, Merli, Francesco, Minoia, Carla, Molinari, Anna Lia, Musuraca, Gerardo, Nassi, Luca, Olivieri, Jacopo, Passamonti, Francesco, Pastore, Domenico, Patti, Caterina, Pelliccia, Sabrina, Pennese, Elsa, Petrucci, Luigi, Piazza, Francesco, Pisani, Francesco, Pizzuti, Michele, Pozzi, Samantha, Puccini, Benedetta, Ravano, Emanuele, Re, Alessandro, Re, Francesca, Rigacci, Luigi, Santoro, Armando, Sassone, Marianna, Spina, Michele, Stefoni, Vittorio, Stelitano, Caterina, Tarantini, Giuseppe, Tarella, Corrado, Tucci, Alessandra, Usai, Sara Veronica, Vallisa, Daniele, Vitolo, Umberto, Zaja, Francesco, Zanni, Manuela, Zilioli, Vittorio Ruggero, Fagerli, Un Merete, Fosså, Alexander, Dabrowska-Iwanicka, Anna, Walewski, Jan, DaSilva, Maria Gomes, Jerkeman, Mats, Azinwi, Ngwa Che, Cavalli, Franco, Deantonio, Letizia, Hitz, Felicitas, Ionescu, Codruta, Mingrone, Walter, Moccia, Alden, Novak, Urban, Pirosa, Maria Cristina, Stathis, Anastasios, Zucca, Emanuele, Kriachok, Iryna, Stepanishyna, Yana, Cozens, Kelly, Cwynarski, Kate, Davies, Andrew, Fox, Christopher P., Illidge, Timothy, Johnson, Rod, McKay, Pam, Mikhaeel, George, Milne, Alison, Nimish, Shah, Osborne, Wendy, Paneesha, Shankara, Pettitt, Andrew, Stevens, Don Ambrose, Barrington, Sally F., Stephane Chauvie Bogdan Malkowski, Luca Ceriani, Metser, Ur, Versari, Annibale, Bonomini, Luisella, and Ielmini, Nicoletta

Published
2024
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12. Gut Microbiota and Obesity

Author

Angelini, Giulia, Russo, Sara, Mingrone, Geltrude, Lenzi, Andrea, Series Editor, Jannini, Emmanuele A., Series Editor, Federici, Massimo, editor, and Menghini, Rossella, editor

Published
2024
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14. PERICARDIOPATIAS

Author

Mingrone, Cláudia, primary, Pereira Lemos Barbosa, Fernanda, additional, Amorim Sampaio, Gabrielli, additional, Victor Nunes, João, additional, Tereza De Oliveira Souza, Maria, additional, Fernando Avezum Do Prado, Luiz, additional, Maria Oliveira Ferreira, Ingridy, additional, Belle Moraes Gonçalves, Aline, additional, and Fernando Avezum do Prado, Luiz, additional

Published
2024
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17. Machine learning based event classification for the energy-differential measurement of the $^\text{nat}$C(n,p) and $^\text{nat}$C(n,d) reactions

Author

Žugec, P., Barbagallo, M., Andrzejewski, J., Perkowski, J., Colonna, N., Bosnar, D., Gawlik, A., Sabate-Gilarte, M., Bacak, M., Mingrone, F., and Chiaveri, E.

Subjects
Physics - Data Analysis, Statistics and Probability, Computer Science - Computer Vision and Pattern Recognition, Nuclear Experiment
Abstract

The paper explores the feasibility of using machine learning techniques, in particular neural networks, for classification of the experimental data from the joint $^\text{nat}$C(n,p) and $^\text{nat}$C(n,d) reaction cross section measurement from the neutron time of flight facility n_TOF at CERN. Each relevant $\Delta E$-$E$ pair of strips from two segmented silicon telescopes is treated separately and afforded its own dedicated neural network. An important part of the procedure is a careful preparation of training datasets, based on the raw data from Geant4 simulations. Instead of using these raw data for the training of neural networks, we divide a relevant 3-parameter space into discrete voxels, classify each voxel according to a particle/reaction type and submit these voxels to a training procedure. The classification capabilities of the structurally optimized and trained neural networks are found to be superior to those of the manually selected cuts., Comment: 11 pages, 5 figures, 2 tables

Published
2022
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18. High accuracy, high resolution 235U(n,f) cross section from n_TOF (CERN) in the thermal to 10 keV energy range

Author

collaboration, n_TOF, Mastromarco, M., Amaducci, S., Colonna, N., Finocchiaro, P., Cosentino, L., Aberle, O., Andrzejewski, J., Audouin, L., Bacak, M., Balibrea, J., Barbagallo, M., Bečvář, F., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Cortés, G., Cortés-Giraldo, M. A., Damone, L. A., Diakaki, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A., Ferreira, P., Furman, V., Göbel, K., García, A. R., Gawlik, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kalamara, A., Kavrigin, P., Kimura, A., Kivel, N., Knapova, I., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Lederer, C., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Macina, D., Manna, A., Marganiec, J., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rauscher, T., Reifarth, R., Rubbia, C., Ryan, J. A., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sedyshev, P., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weiss, C., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Nuclear Experiment
Abstract

The 235U(n,f) cross section was measured in a wide energy range (25 meV - 170 keV) at the n_TOF facility at CERN, relative to 6Li(n,t) and 10B(n,alpha) standard reactions, with high resolution and accuracy, with a setup based on a stack of six samples and six silicon detectors placed in the neutron beam. In this paper we report on the results in the region between thermal and 10 keV neutron energy. A resonance analysis has been performed up to 200 eV, with the code SAMMY. The resulting fission kernels are compared with the ones extracted on the basis of the resonance parameters of the most recent major evaluated data libraries. A comparison of the n_TOF data with the evaluated cross sections is also performed from thermal to 10 keV neutron energy for the energy-averaged cross section in energy groups of suitably chosen width. A good agreement is found in average between the new results and the latest evaluated data files ENDF-B/VIII and JEFF-3.3, as well as with respect to the IAEA reference files. However, some discrepancies are still present in some specific energy regions. The new dataset here presented, characterized by unprecedented resolution and accuracy, can help improving the evaluations in the Resolved Resonance Region and up to 10 keV, and reduce the uncertainties that affect this region.

Published
2022

20. Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial

Author

Abe, Mitsunori, Abhaichand, Rajpal K, Abhayaratna, Walter P, Abhyankar, Atul, Abidin, Imran B Zainal, Abou Assi, Hiba, Accini Mendoza, Jose L, Adas, Mine, Agaiby, John M, Agarwal, Devendra K, Agha, Maher, Ahmed, Azazuddin, Ahtiainen, Petteri, Aigner, Elmar, Ajay, Naik, Ali, Norsiah, Al-Karadsheh, Amer, Allison, Roy, Allison, Dale C, Alpenidze, Diana, Altuntas, Yuksel, Al-Zoebi, Ayham, Ambuj, Roy, Amerena, John, Anderson, Robert J, Ando, Toshiaki, Andrews, Robert, Antonova, Elizaveta, Appel, Karl-Friedrich, Arantes, Flávia B, Araz, Mustafa, Arbel, Yaron, Arenas León, José L, Argyrakopoulou, Georgia, Ariani, Mehrdad, Arias Mendoza, Maria A, Arif, Ahmed A, Arneja, Jaspal, Aroda, Vanita R, Aronne, Louis J, Arstall, Margaret, Asamoah, Njaimeh, Asanin, Milika, Audish, Hanid, Avram, Rodica, Badat, Aysha, Badiu, Corin V, Bakdash, Wa'el, Bakiner, Okan S, Bandezi, Vuyokazi N, Bang, Liew H, Bansal, Sandeep, Baranyai, Marietta, Barbarash, Olga, Barber, Mark, Barnum, Otis, Barone Rochette, Gilles, Bashkin, Amir, Baum, Seth, Bays, Harold E, Bazzoni Ruiz, Alberto E, Beckowski, Maciej, Beerachee, Yaswin, Bellary, Srikanth, Belousova, Lidia, Berk, Martin, Bernstein, Marc, Berra, Cesare, Beshay, Isaac, Bhagwat, Ajit, Bhan, Arti, Biggs, William C, Billings, Liana, Bitar, Fahed, Block, Bradley, Bo, Simona, Bogdanski, Pawel, Bolshakova, Olga O, Boshchenko, Alla A, Bosworth, Hayden, Botero Lopez, Rodrigo, Bôttcher, Morten, Bourgeois, Ronald, Brautigam, Donald, Breton, Cristian F, Broadley, Andrew, Brockmyre, Andrew P, Brodie, Steven K, Bucci, Marco, Budincevic, Hrvoje, Budoff, Matthew J, Buffman, Barry, Buljubasic, Nediljka, Buranapin, Supawan, Burgess, Lesley, Burguera, Bartolomé, Buriakovska, Olena, Buscemi, Silvio, Busch, Robert, Buse, John B, Buynak, Robert, Byrne, Maria, Caceaune, Elena, Cadena Bonfanti, Alberto J, Calinescu, Cornell V, Call, Robert S, Canecki Varzic, Silvija, Cannon, Kevin, Capehorn, Matt, Cariou, Bertrand, Carr, Jeffrey, Carrillo-Jimenez, Rodolfo, Casas, Marcelo, Castro, Almudena, Celik, Ahmet, Cercato, Cintia, Cermak, Ondrej, Cha, James Y, Chacon, Carolina, Chaicha-Brom, Tira, Chandra, Sandeep, Chettibi, Mohamed, Chevts, Julia, Christopher, Johann, Chrustowski, Witold, Cif, Adriana, Clark, Rebecca, Clark, Wayne, Clifford, Piers, Coetzee, Kathleen, Cogni, Giulia, Colao, Anna Maria, Colquhoun, David M, Concha, Mauricio, Condit, Jonathan, Constance, Christian, Constantin, Ciprian, Constantinescu, Silviana, Corbett, Clive, Cornett, George M, Correia, Marcelo, Cortinovis, Fiorenzo, Cosma, Dana, Creely, Steven, Cross, David, Curtis, Brian, Czochra, Wojciech, Daboul, Nizar Y, Dagdelen, Selcuk, D'agostino, Ronald, Dang, Cuong, Datta, Sudip, Davuluri, Ashwini K, Dawood, Saleem Y, De Jong, Douwe M, De La Cuesta, Carmen, De Los Rios Ibarra, Manuel O, De Pablo, Carmen, De Pauw, Michel, Dela Llana, Alexander, Delibasic, Maja, Delic-Brkljacic, Diana, Demicheli, Thibaud, Denger, Ralf J, Desai, Devang, Desai, Piyush, Desouza, Cyrus V, Dicker, Dror, Djenic, Nemanja, Dobson, Simon, Doi, Masayuki, Doran, Jesse A, Dorman, Reinhart, Dotta, Francesco, Dukes, Carl E, Duronto, Ernesto, Durst, Ronen, Dvoryashina, Irina V, Ebrahim, Iftikhar O, Eggebrecht, Holger, Egstrup, Kenneth, Ekinci, Elif I, Eliasson, Björn, Eliasson, Ken, Enache, Georgiana, Enculescu, Dan, English, Patrick, Ermakova, Polina, Ershova, Olga, Ezaki, Hirotaka, Ezhov, Marat, Farias, Eduardo, Farias, Javier M, Farsky, Pedro S, Ferreira, Daniel, Filteau, Pierre, Finneran, Matthew P, Folkens, Eric M, Fonseca, Alberto G, Fonseca, Luisa, Fordan, Steven, Fourie, Nyda, França, Sara, Franco, Denise R, Franek, Edward, Friedman, Keith, Frittitta, Lucia, Froer, Michael, Fuckar, Krunoslav, Fujii, Kenshi, Fujita, Ryoko, Fukushima, Yasushi, Fulat, Mohamed, Fulwani, Mahesh, Gajos, Grzegorz, Galyavich, Albert, Gambill, Michael L, Gandotra, Dheeraj, Winston, Gandy, Jr., Garcia Hernandez, Pedro A, García Reza, Raymundo, Garg, Naveen, Garg, Sandeep, Garvey, William T, Garza, Juan C, Gatta-Cherifi, Blandine, Gelev, Valeri, Geller, Steven A, Geohas, Jeffrey G, Georgiev, Borislav, Ghazi, Adline, Gilbert, Matthew P, Gilinskaya, Olga, Gislason, Gunnar, Gogas Yavuz, Dilek, González Albarrán, Olga, Gordeev, Ivan G, Gorton, Sidney C, Goudev, Assen, Gretland Valderhaug, Tone, Groenemeijer, Bjorn, Gul, Ibrahim, Gullestad, Lars, Gurieva, Irina, Guseva, Galina N, Hagenow, Andreas, Haluzik, Martin, Halvorsen, Sigrun, Hammoudi, Naima, Hanaoka, Keiichi, Hancu, Nicolae, Hanusch, Ursula, Harris, Kathleen, Harris, Barry, Hartleib, Michael, Hartman, Aaron N, Hata, Yoshiki, Heimer, Brian, Herman, Lee, Herzog, William, Hewitt, Eric, Heymer, Peter, Hiremath, Shirish, Hjelmesaeth, Joeran, Høgalmen, Rasmus Geir, Høivik, Hans Olav, Holmer, Helene, Horoshko, Olha, Houser, Patricia M, Hove, Jens D, Hsieh, I-Chang, Hulot, Jean-Sébastien, Hussein, Zanariah, Ilashchuk, Tetiana, Ilveskoski, Erkki, Ipatko, Irina, Iranmanesh, Ali, Isawa, Tsuyoshi, Issa, Moises, Iteld, Bruce, Iwasawa, Takamasa, Jabbar, Danish, Jackson, Richard A, Jackson-Voyzey, Ewart, Jacob, Stephan, Jaffrani, Naseem A, Jardula, Michael F, Jastreboff, Ania, Jensen, Svend E, Jerkins, Terri, Jimenez-Ramos, Silvia A, Jitendra Pal Singh, Sawhney, Johnson, Wallace, Joyce, John M, Jozefowska, Malgorzata, Jugnundan, Prakash, Jungmair, Wolfgang, Jurowiecki, Jaroslaw, Kadokami, Toshiaki, Kahali, Dhiman, Kahrmann, Gerd, Kaiser, Sergio E, Kalmucki, Piotr, Kanadasi, Mehmet, Kandath, David, Kania, Grzegorz, Kannan, J, Kapp, Cornelia, Karczmarczyk, Agnieszka, Kartalis, Athanasios, Kaser, Susanne, Kasim, Sazzli Shahlan, Kastelic, Richard, Kato, Toshiaki, Katova, Tzvetana, Kaul, Upendra, Kautzky-Willer, Alexandra, Kawanishi, Masahiro, Kayikcioglu, Meral, Kazakova, Elena E, Keeling, Philip, Kempe, Hans-Peter, Kereiakes, Dean J, Kerneis, Mathieu, Keski-Opas, Tiina, Khadra, Suhail, Khaisheva, Larisa, Kharakhulakh, Marina, Khlevchuk, Tatiana, Khoo, Jeffrey, Kiatchoosakun, Songsak, Kinoshita, Noriyuki, Kinoshita, Masaharu, Kitamura, Ryoji, Kiyosue, Arihiro, Klavina, Irina, Klein, Eric J, Klimsa, Zdenek, Klonoff, David, Klug, Eric, Kobalava, Zhanna, Kodera, Satoshi, Koga, Tokushi, Kokkinos, Alexander, Koleckar, Pavel, Könyves, László, Koren, Michael J, Kormann, Adrian P, Kostner, Karam, Kreutzmann, Kristin, Krishinan, Saravanan, Krishnasamy, Sathya S, Krivosheeva, Inga, Kruljac, Ivan, Kubicki, Ted, Kuchar, Ladislav, Kujawiak, Monika, Kunishige, Hideyuki, Kurtinecz, Melinda, Kurtz Lisboa, Hugo R, Kushnir, Mykola, Kyyak, Yulian, Lace, Arija, Lakka, Timo, Lalic, Nebojsa, Lalic, Katarina, Lambadiari, Vaia, Lanaras, Leonidas, Lang, Chim, Langlois, Marie-France, Lash, Joseph, Latkovskis, Gustavs, Lau, David, Lazcano Soto, José Roberto, Le Roux, Carel, Ledesma, Gilbert N, Lee, Li Yuan, Lee, Thung-Lip, Lee, Kelvin, Lehrke, Michael, Leite, Silmara O, Leksycka, Agata, Lenzmeier, Thomas, Leonetti, Frida, Leonidova, Viktoriia, Lepor, Norman, Leung, Melissa, Levchenko, Olena, Levins, Peter, Levy, Louis J, Lewis, Matthew, Liberopoulos, Evangelos, Liberty, Idit, Lindholm, Carl-Johan, Lingvay, Ildiko, Linhart, Ales, Liu, Ming-En, Liu, Jenny, Lofton, Holly, Logemann, Timothy, Lombaard, Johannes J, Lombard, Landman, Lorraine, Richard, Lovell, Charles F, Ludvik, Bernhard, Lukaszewicz, Monika, Lupkovics, Géza, Lupovitch, Steven, Lupu, Sirona, Lynch, Mary, Lysak, Zoreslava, Lysenko, Tatyana A, Maeda, Hajime, Maeda, Itaru, Mæng, Michael, Mahajan, Ajay U, Maher, Vincent, Maia, Lilia N, Makotoko, Ellen M, Malavazos, Alexis, Malecha, Jan, Malicherova, Emilia, Manita, Mamoru, Mannucci, Edoardo, Mareev, Viacheslav, Marin, Liliana, Markova, Tatiana, Marso, Steven P, Martens, F.M.A.C., Martinez, Cuper, Martinez Cano, Carlos A, Martins, Cristina, Masmiquel Comas, Luis, Matsumoto, Takashi, Mcdonald, Kenneth, Mcgowan, Barbara, Mcgrew, Frank, Mclean, Barry K, Mcpherson, David D, Merino Torres, Juan Francisco, Meyers, Peter, Meyhöfer, Sebastian, Mezquita Raya, Pedro, Milanova, Maria, Milicic, Davor, Miller, Gary, Mills, Richard E, Mîndrescu, Nicoleta M, Mingrone, Geltrude, Minkova, Dotska A, Mirani, Marco, Miras, Alexander, Mistodie, Cristina V, Mitomo, Satoru, Mittal, Sanjay, Miyake, Taiji, Miyamoto, Naomasa, Molony, David, Monteiro, Pedro, Mooe, Thomas, Moosa, Naeem, Morales Portillo, Cristobal, Morales Villegas, Enrique C, Morawski, Emily J, Morbey, Claire, Morin, Robert P, Morisaki, Kuniaki, Morosanu, Magdalena, Mosenzon, Ofri, Mostovoy, Yuriy, Munir, Iqbal, Muratori, Fabrizio, Murray, Ryan, Murthy, Avinash, Myint, Min, Myshanych, Galyna, Nafornita, Valerica, Nagano, Takuya, Nair, Sunil, Nakhle, Samer N, Natsuaki, Masahiro, Nayak, Bindu M, Nibouche, Djamel Eddine, Nicholls, Stephen, Nicolau, José C, Nicolescu, Georgiana, Nierop, Peter, Niskanen, Leo, Ntaios, George, Nygård, Ottar Kjell, Oaks, Joshua B, Obrezan, Andrey, O'donnell, Philip, Oguri, Mitsutoshi, Oguzhan, Abdurrahman, Oh, Fumiki, Ohsugi, Mitsuru, Okada, Yoshio, Okayama, Hideki, Onaca, Adriana, Onaka, Haruhiko, Oneil, Patrick, Ong, Tiong Kiam, Ong, Stephen, Ono, Yasuhiro, Opsahl, Paul J, Ostrowska, Lucyna, Oviedo, Alejandra, Ozdogan, Oner, Ozpelit, Ebru, Pagkalos, Emmanouil, Pagotto, Uberto, Páll, Dénes, Pandey, Amritanshu- Shekhar, Parkhomenko, Oleksandr, Parvathareddy, Krishna Malakondareddy, Patel, Minesh B, Patsilinakos, Sotirios, Paul, Neil, Pedersen, Sue, Pereira, Isabel, Pereira, Edward Scott, Perez Terns, Paula, Perez-Vargas, Elba A, Pergaeva, Yulia, Perkelvald, Alexander, Peskov, Andrey B, Peter, Jonathan, Peters, Karina, Petit, Catherine, Petrov, Ivo, Philis-Tsimikas, Athena, Pietilä, Mikko, Pinto, Fausto, Piros, Annamária, Piyayotai, Dilok, Platonov, Dmitriy, Poirier, Paul, Pop, Lavinia, Popa, Bogdan, Pop-Busui, Rodica, Poremba, John, Porto, Alejandro, Postadzhiyan, Arman, Pothineni, Ramesh B, Potu, Ranganatha P, Powell, Talessa, Prafulla, Kerkar G, Prager, Rudolf, Prakova-Teneva, Zhulieta R, Pratley, Richard E, Price, Hermione, Pulka, Grazyna, Pullman, John, Punt, Zelda E, Purighalla, Raman S, Purnell, Peter, Qureshi, Mansoor, Rabasa-Lhoret, Remi, Raikhel, Marina A, Rancane, Gita, Randeva, Harpal, Rasouli, Neda, Reurean Pintilei, Delia V, Reyes, Ciro R, Rezgale, Inga, Rice, Eva, Riley, Thaddeus H, Risser, Joseph A, Ristic, Arsen, Rivas Fernández, Margarita, Robbins, David, Robitaille, Yves, Rodbard, Helena W, Rodriguez Plazas, Jaime A, Römer, T.J., Rosen, Glenn, Rosman, Dr Azhari, Rossi, Paulo, Rudenko, Leonid, Ruffin, Omari, Ruhani, Anwar Irawan, Runev, Nikolay, Ruyatkin, Dmitriy, Ruzic, Alen, Ryabov, Vyacheslav V, Rydén, Lars, Saggar, Suraj, Sakamoto, Tomohiro, Salter, Tim, Samal, Aditya K, Samoilova, Yulia, Sanabria, Hugo D, Sancak, Seda, Sangrigoli, Renee, Sansanayudh, Nakarin, Santini, Ferruccio, Saraiva, José F, Sardinov, Ruslan, Sargeant, William, Sari, Ramazan, Sathananthan, Airani, Sathyapalan, Thozhukat, Sato, Atsushi, Sauter, Joachim, Sbraccia, Paolo, Schaap, J., Schaum, Thomas, Schiele, François, Scott, John, Segal Lieberman, Gabriella, Segner, Alexander, Senior, Roxy, Sergeeva-Kondrachenko, Marina Y, Serota, Harvey, Serusclat, Pierre, Sethi, Rishi, Shah, Manoj K, Shah, Neerav, Shalaev, Sergey, Sharma, Raj, Sharma, Sumeet, Shaydyuk, Oksana, Shea, Heidi C, Shechter, Michael, Shehadeh, Naim, Shirazi, Mitra, Shlesinger, Yshay, Shneker, Ayham, Shutemova, Elena, Siasos, Gerasimos, Siddiqui, Imran A, Sidey, Jennifer, Sigal, Felix, Sime, Iveta, Singh, Narendra, Siraj, Elias, Sivalingam, Kanagaratnam, Skoczylas, Grzegorz, Smith, Stephen K, Smolenskaya, Olga, Snyder, Brian, Sofer, Yael, Sofley, C.W., Solano, Royce, Sonmez, Yusuf A, Sorokin, Maxim, Soto González, Alfonso, Sotolongo, Carlos, Soufer, Joseph, Soyluk Selcukbiricik, Ozlem, Spaic, Tamara, Spriggs, Douglas, Sreenan, Seamus, Stahl, Hans-Detlev, Stamatelopoulos, Kimon, Stanislavchuk, Mykola, Stankovic, Goran, Stasek, Josef, Steg, Gabriel, Steindorf, Joerg, Stephan, Dominique, Stewart, John, Still, Christopher, St-Maurice, Francois, Stogowska-Nikiciuk, Barbara, Stoker, Jeff, Stokic, Edita, Strzelecka, Anna, Sturm, Kerstin, Sueyoshi, Atsushi, Sugiura, Toshiyuki, Sultan, Senan, Suplotova, Lyudmila A, Suwanagool, Arisara, Suwanwalaikorn, Sompongse, Sveklina, Tatiana, Swanson, Neil, Swart, Henk, Swenson, Bradley P, Szyprowska, Ewa, Tait, Graeme, Takács, Róbert, Takeuchi, Yuzo, Tamirisa, Aparna, Tanaka, Hideki, Tatovic, Danijela, Tellier, Guy, Teragawa, Hiroki, Teterovska, Dace, Thomas, Nihal, Thuan, Jean-Francois, Tinahones, Francisco, Tisheva-Gospodinova, Snezhanka, Toarba, Cristina, Todoriuk, Liudmyla, Tokmakova, Mariya, Tonstad, Serena, Toplak, Hermann, Tran, Henry, Tripathy, Devjit, Trusau, Aliaksandr, Tsabedze, Nqoba, Tsougos, Elias, Tsoukas, George M, Tuccinardi, Dario, Tuna, Mazhar M, Turatti, Luiz A, Tziomalos, Konstantinos, Udommongkol, Chesda, Ueda, Osamu, Ukkola, Olavi, Unubol, Mustafa, Urbach, Dorothea, Urina Triana, Miguel A, Usdan, Lisa, Vaidya, Bijay, Vale, Noah, Vallieres, Gerald, Van Beek, Andre P, Van De Borne, Philippe, Van Der Walt, Eugene, Van Der Zwaan, C., Van Nieuwenhuizen, Elane, Van Zyl, Louis, Vanduynhoven, Philippe, Varghese, Kiron, Vasileva, Svetla P, Vassilev, Dobrin, Vathesatogkit, Prin, Velychko, Valentyna, Vercammen, Chris, Verges, Bruno, Verma, Subodh, Verwerft, Jan, Vesela, Alica, Veselovskaya, Nadezhda G, Vettor, Roberto, Veze, Irina, Vijan, Vinod, Vijayaraghavan, Ram, Villarino, Adriana, Vincent, Royce, Vinogradova, Oksana, Vishlitzky, Victor, Vlad, Adrian, Vladu, Ionela Mihaela, Vo, Anthony, Von Engelhardt, Charlotte, Von Münchhausen, Candy, Vorobyeva, Olga, Vossenberg, T., Vrolix, Mathias, Vukicevic, Marjana, Vyshnyvetskyy, Ivan, Wadvalla, Shahid, Wagner, Jan, Wakeling, John, Wallace, James, Wan Mohamed, Wan Mohd Izani, Wander, Gurpreet S, Ward, Kathleen, Warren, Mark L, Watanabe, Atsuyuki, Weber, Bruce, Weintraub, Howard, Weisnagel, John, Welker, James, Wendisch, Ulrich, Wenocur, Howard S, Wierum, Craig, Wilding, John, William, Maged, Wilson, Pete, Wilson, Jonathan P, Wong, Yuk-Ki, Wongcharoen, Wanwarang, Wozniak, Iwona, Wu, Chau-Chung, Wyatt, Nell, Wynne, Alan, Yamaguchi, Hiroshi, Yamasaki, Masahiro, Yazici, Dilek, Yeh, Hung-I, Yotov, Yoto, Yuan, Qingyang, Zacher, Jeffrey, Zagrebelnaya, Olga, Zaidman, Cesar J, Zalevskaya, Alsu, Zarich, Stuart, Zatelli, Maria Chiara, Zeller, Helga, Zhdanova, Elena A, Zornitzki, Taiba, Zrazhevskiy, Konstantin, Zykov, Mikhail, Lincoff, A Michael, Ryan, Donna H, Colhoun, Helen M, Deanfield, John E, Emerson, Scott S, Kahn, Steven E, Kushner, Robert F, Plutzky, Jorge, Brown-Frandsen, Kirstine, Hovingh, G Kees, Hardt-Lindberg, Soren, Tornøe, Christoffer W, Deanfield, John, Scirica, Benjamin M, Ryan, Donna, Kosiborod, Mikhail N, Hardt-Lindberg, Søren, Frenkel, Ofir, Weeke, Peter E, Rasmussen, Søren, Lang, Chim C, and Urina-Triana, Miguel

Published
2024
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22. Measurement of the prompt fission γ235-rays from slow neutron-induced fission of γ235U with STEFF

Author

Wright, T., Smith, A. G., Sosnin, N. V., Bennett, S. A., Davies, P. J., Popescu, A. V., Ryan, J. A., Sekhar, A., Warren, S., Aberle, O., Amaducci, S., Andrzejewski, J., Audouin, L., Bacak, M., Balibrea, J., Barbagallo, M., Bečvář, F., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Damone, L. A., Diakaki, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A., Ferreira, P., Finocchiaro, P., Furman, V., Göbel, K., García, A. R., Gawlik-Ramięga, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kalamara, A., Kavrigin, P., Kimura, A., Kivel, N., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Lederer-Woods, C., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Macina, D., Manna, A., Marganiec, J., Martínez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rauscher, T., Reifarth, R., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sedyshev, P., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Weiss, C., Woods, P. J., and Žugec, P.

Published
2024
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23. Decreased circulating IPA levels identify subjects with metabolic comorbidities: A multi-omics study

Author

Marta Ballanti, Lorenzo Antonetti, Maria Mavilio, Viviana Casagrande, Alessandro Moscatelli, Daniele Pietrucci, Adelaide Teofani, Chiara Internò, Marina Cardellini, Omero Paoluzi, Giovanni Monteleone, Philippe Lefebvre, Bart Staels, Geltrude Mingrone, Rossella Menghini, and Massimo Federici

Subjects
IPA, Gut, Cross-omics, Untargeted metabolomics, Genomics, Diagnostic, Therapeutics. Pharmacology, RM1-950
Abstract

In recent years several experimental observations demonstrated that the gut microbiome plays a role in regulating positively or negatively metabolic homeostasis. Indole-3-propionic acid (IPA), a Tryptophan catabolic product mainly produced by C. Sporogenes, has been recently shown to exert either favorable or unfavorable effects in the context of metabolic and cardiovascular diseases. We performed a study to delineate clinical and multiomics characteristics of human subjects characterized by low and high IPA levels. Subjects with low IPA blood levels showed insulin resistance, overweight, low-grade inflammation, and features of metabolic syndrome compared to those with high IPA. Metabolomics analysis revealed that IPA was negatively correlated with leucine, isoleucine, and valine metabolism. Transcriptomics analysis in colon tissue revealed the enrichment of several signaling, regulatory, and metabolic processes. Metagenomics revealed several OTU of ruminococcus, alistipes, blautia, butyrivibrio and akkermansia were significantly enriched in highIPA group while in lowIPA group Escherichia-Shigella, megasphera, and Desulfovibrio genus were more abundant.Next, we tested the hypothesis that treatment with IPA in a mouse model may recapitulate the observations of human subjects, at least in part. We found that a short treatment with IPA (4 days at 20/mg/kg) improved glucose tolerance and Akt phosphorylation in the skeletal muscle level, while regulating blood BCAA levels and gene expression in colon tissue, all consistent with results observed in human subjects stratified for IPA levels. Our results suggest that treatment with IPA may be considered a potential strategy to improve insulin resistance in subjects with dysbiosis.

Published
2024
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24. Dicarboxylic acids counteract the metabolic effects of a Western diet by boosting energy expenditure

Author

Castagneto-Gissey, Lidia, Bornstein, Stefan R., and Mingrone, Geltrude

Subjects
Health care industry
Abstract

Obesity has reached pandemic proportion not only in the West but also in other countries around the world; it is now one of the leading causes of death worldwide. A Western diet is rich in saturated fats and provides more calories than necessary, contributing to the rise of the obesity rate. It also promotes the development of liver steatosis, insulin resistance, hyperglycemia, and hyperlipidemia. In this issue of theJCI, Goetzman and colleagues describe the effects of consuming dicarboxylic acids (DAs) as an alternative source of dietary fat. The 12-carbon dicarboxylic acid (DC12) was administered to mice at 20% of their daily caloric intake for nine weeks in place of triglycerides. Notably, the change in diet increased the metabolic rate, reduced body fat, reduced liver fat, and improved glucose tolerance. These findings highlight DAs as useful energy nutrients for combatting obesity and treating various metabolic disorders., Dicarboxylic acids as the missing fourth nutrient Medium- and long-chain dicarboxylic acids (DAs) are present in higher plants and animals, deriving from the ro-oxidation of fatty acids (1). In higher [...]

Published
2024
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29. High-resolution cross section measurements for neutron interactions on 89Y with incident neutron energies up to 95 keV

Author

Tagliente, G., Milazzo, P. M., Paradela, C., Kopecky, S., Vescovi, D., Alaerts, G., Damone, L. A., Heyse, J., Krtička, M., Schillebeeckx, P., Mengoni, A., Wynants, R., Valenta, S., Aberle, O., Alcayne, V., Amaducci, S., Andrzejewski, J., Audouin, L., Babiano-Suarez, V., Bacak, M., Barbagallo, M., Bécares, V., Bečvář, F., Bellia, G., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A. S., Busso, M., Caamaño, M., Caballero, L., Calviani, M., Calviño, F., Cano-Ott, D., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Colonna, N., Cortés, G. P., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Eleme, Z., Fernández-Domíngez, B., Ferrari, A., Ferro-Gonçalves, I., Finocchiaro, P., Furman, V., Garg, R., Gawlik, A., Gilardoni, S., Glodariu, T., Göbel, K., González-Romero, E., Guerrero, C., Gunsing, F., Heinitz, S., Jenkins, D. G., Jericha, E., Kadi, Y., Käppeler, F., Kimura, A., Kivel, N., Kokkoris, M., Kopatch, Y., Kurtulgil, D., Ladarescu, I., Larsen, A. C., Lederer-Woods, C., Lerendegui-Marco, J., Lo Meo, S., Lonsdale, S. J., Lugaro, M., Macina, D., Manna, A., Martínez, T., Masi, A., Massimi, C., Mastinu, P. F., Mastromarco, M., Matteucci, F., Maugeri, E., Mazzone, A., Mendoza, E., Michalopoulou, V., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Piersanti, L., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Ramos Doval, D., Reifarth, R., Rochman, D., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schumann, D., Smith, A. G., Spelta, M., Sosnin, N., Stamatopoulos, A., Tain, J. L., Talip, Z., Tarifeño-Saldivia, A. E., Tassan-Got, L., Torres-Sánchez, P., Tsinganis, A., Ulrich, J., Urlass, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T. J., and Žugec, P.

Published
2024
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30. Imaging neutron capture cross sections: i-TED proof-of-concept and future prospects based on Machine-Learning techniques

Author

Babiano-Suárez, V., Lerendegui-Marco, J., Balibrea-Correa, J., Caballero, L., Calvo, D., Ladarescu, I., Domingo-Pardo, C., Calviño, F., Casanovas, A., Tarifeño-Saldivia, A., Alcayne, V., Guerrero, C., Millán-Callado, M. A., González, M. T. Rodríguez, Barbagallo, M., Aberle, O., Amaducci, S., Andrzejewski, J., Audouin, L., Bacak, M., Bennett, S., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Busso, M., Caamaño, M., Calviani, M., Cano-Ott, D., Cerutti, F., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Davies, P. J., Diakaki, M., Dietz, M., Dressler, R., Ducasse, Q., Dupont, E., Durán, I., Eleme, Z., Fern\', B., ez-Domínguez, Ferrari, A., Finocchiaro, P., Furman, V., Göbel, K., Garg, R., Gawlik, A., Gilardoni, S., Gonçalves, I. F., González-Romero, E., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Junghans, A., Käppeler, F., Kadi, Y., Kimura, A., Knapova, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Lederer-Woods, C., Leeb, H., Lonsdale, S. J., Macina, D., Manna, A., Martinez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Moreno-Soto, J., Musumarra, A., Negret, A., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Persanti, L., Petrone, C., Pirovano, E., Porras, I., Praena, J., Quesada, J. M., Ramos-Doval, D., Rauscher, T., Reifarth, R., Rochman, D., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A. G., Sosnin, N. V., Sprung, P., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tassan-Got, L., Thomas, Th., Torres-Sánchez, P., Tsinganis, A., Ulrich, J., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Physics - Instrumentation and Detectors, Astrophysics - Instrumentation and Methods for Astrophysics, Nuclear Experiment
Abstract

i-TED is an innovative detection system which exploits Compton imaging techniques to achieve a superior signal-to-background ratio in ($n,\gamma$) cross-section measurements using time-of-flight technique. This work presents the first experimental validation of the i-TED apparatus for high-resolution time-of-flight experiments and demonstrates for the first time the concept proposed for background rejection. To this aim both $^{197}$Au($n,\gamma$) and $^{56}$Fe($n, \gamma$) reactions were measured at CERN n\_TOF using an i-TED demonstrator based on only three position-sensitive detectors. Two \cds detectors were also used to benchmark the performance of i-TED. The i-TED prototype built for this study shows a factor of $\sim$3 higher detection sensitivity than state-of-the-art \cds detectors in the $\sim$10~keV neutron energy range of astrophysical interest. This paper explores also the perspectives of further enhancement in performance attainable with the final i-TED array consisting of twenty position-sensitive detectors and new analysis methodologies based on Machine-Learning techniques., Comment: 16 pages, 16 figures

Published
2020
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31. A synchronization method for the multi-channel silicon telescope

Author

Žugec, P., Barbagallo, M., Andrzejewski, J., Perkowski, J., Colonna, N., Bosnar, D., Sabaté, A. Gawlik M., Mingrone, -Gilarte M. Bacak F., and Chiaveri, E.

Subjects
Physics - Instrumentation and Detectors
Abstract

A simple method is presented for the simultaneous off-line synchronization of the digitally recorded data-streams from a multi-channel silicon telescope. The method is based both on the synchronization between the separate pairs of silicon strips and on the synchronization relative to an external timing device. Though only a reduced subset of these constraints is necessary in ideal circumstances, it is shown that this minimal set of conditions may not be sufficient for adequate synchronization in all cases. All available sources of information are therefore considered, in order to constrain the final synchronization as well as possible., Comment: 8 pages, 7 figures

Published
2020
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32. Study of a data analysis method for the angle resolving silicon telescope

Author

Žugec, P., Barbagallo, M., Andrzejewski, J., Perkowski, J., Colonna, N., Bosnar, D., Gawlik, A., Sabate-Gilarte, M., Bacak, M., Mingrone, F., Chiaveri, E., and Šako, M.

Subjects
Physics - Data Analysis, Statistics and Probability, Nuclear Experiment
Abstract

A new data analysis method is developed for the angle resolving silicon telescope introduced at the neutron time of flight facility n_TOF at CERN. The telescope has already been used in measurements of several neutron induced reactions with charged particles in the exit channel. The development of a highly detailed method is necessitated by the latest joint measurement of the $^{12}$C($n,p$) and $^{12}$C($n,d$) reactions from n_TOF. The reliable analysis of these data must account for the challenging nature of the involved reactions, as they are affected by the multiple excited states in the daughter nuclei and characterized by the anisotropic angular distributions of the reaction products. The unabridged analysis procedure aims at the separate reconstruction of all relevant reaction parameters - the absolute cross section, the branching ratios and the angular distributions - from the integral number of the coincidental counts detected by the separate pairs of silicon strips. This procedure is tested under the specific conditions relevant for the $^{12}$C($n,p$) and $^{12}$C($n,d$) measurements from n_TOF, in order to assess its direct applicability to these experimental data. Based on the reached conclusions, the original method is adapted to a particular level of uncertainties in the input data., Comment: 23 pages, 7 figures

Published
2020
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36. Liver biopsy-based validation, confirmation and comparison of the diagnostic performance of established and novel non-invasive steatotic liver disease indexes: Results from a large multi-center study

Author

Kouvari, Matina, Valenzuela-Vallejo, Laura, Guatibonza-Garcia, Valentina, Polyzos, Stergios A., Deng, Yixiang, Kokkorakis, Michail, Agraz, Melih, Mylonakis, Sophia C., Katsarou, Angeliki, Verrastro, Ornella, Markakis, Georgios, Eslam, Mohammed, Papatheodoridis, Georgios, George, Jacob, Mingrone, Geltrude, and Mantzoros, Christos S.

Published
2023
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37. Mechanisms and clinical relevance of the bidirectional relationship of viral infections with metabolic diseases

Author

Perakakis, Nikolaos, Harb, Hani, Hale, Benjamin G, Varga, Zsuzsanna, Steenblock, Charlotte, Kanczkowski, Waldemar, Alexaki, Vasileia Ismini, Ludwig, Barbara, Mirtschink, Peter, Solimena, Michele, Toepfner, Nicole, Zeissig, Sebastian, Gado, Manuel, Abela, Irene Alma, Beuschlein, Felix, Spinas, Giatgen A, Cavelti-Weder, Claudia, Gerber, Philipp A, Huber, Michael, Trkola, Alexandra, Puhan, Milo A, Wong, Wendy Wei-Lynn, Linkermann, Andreas, Mohan, Viswanathan, Lehnert, Hendrik, Nawroth, Peter, Chavakis, Triantafyllos, Mingrone, Geltrude, Wolfrum, Christian, Zinkernagel, Annelies S, and Bornstein, Stefan R

Published
2023
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39. Review and new concepts for neutron-capture measurements of astrophysical interest

Author

Domingo-Pardo, C., Babiano-Suarez, V., Balibrea-Correa, J., Caballero, L., Ladarescu, I., Lerendegui-Marco, J., Tain, J. L., Calviño, F., Casanovas, A., Segarra, A., Tarifeño-Saldivia, A. E., Guerrero, C., Millán-Callado, M. A., Quesada, J. M., Rodríguez-González, M. T., Aberle, O., Alcayne, V., Amaducci, S., Andrzejewski, J., Audouin, L., Bacak, M., Barbagallo, M., Bennett, S., Berthoumieux, E., Bosnar, D., Brown, A. S., Busso, M., Caamaño, M., Calviani, M., Cano-Ott, D., Cerutti, F., Chiaveri, E., Colonna, N., Cortés, G. P., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Davies, P. J., Diakaki, M., Dietz, M., Dressler, R., Ducasse, Q., Dupont, E., Durán, I., Eleme, Z., Fernández-Domíngez, B., Ferrari, A., Ferro-Goncalves, I., Finocchiaro, P., Furman, V., Garg, R., Gawlik, A., Gilardoni, S., Göbel, K., González-Romero, E., Gunsing, F., Heyse, J., Jenkins, D. G., Jericha, E., Jiri, U., Junghans, A., Kadi, Y., Käppeler, F., Kimura, A., Knapová, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Lederer-Woods, C., Lonsdale, S. -J., Macina, D., Manna, A., Martínez, T., Masi, A., Massimi, C., Mastinu, P. F., Mastromarco, M., Maugeri, E., Mazzone, A., Mendoza, E., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Moreno-Soto, J., Musumarra, A., Negret, A., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Petrone, C., Piersanti, L., Pirovano, E., Porras, I., Praena, J., Doval, D. Ramos, Reifarth, R., Rochman, D., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A. G., Sosnin, N., Sprung, P., Stamatopoulos, A., Tagliente, G., Tassan-Got, L., Thomas, B., Torres-Sánchez, P., Tsinganis, A., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T. J., Zugec, P. v, and Collaboration, The n_TOF

Subjects
Physics - Instrumentation and Detectors
Abstract

The idea of slow-neutron capture nucleosynthesis formulated in 1957 triggered a tremendous experimental effort in different laboratories worldwide to measure the relevant nuclear physics input quantities, namely ($n,\gamma$) cross sections over the stellar temperature range (from few eV up to several hundred keV) for most of the isotopes involved from Fe up to Bi. A brief historical review focused on total energy detectors will be presented to illustrate how, advances in instrumentation have led, over the years, to the assessment and discovery of many new aspects of $s$-process nucleosynthesis and to the progressive refinement of theoretical models of stellar evolution. A summary will be presented on current efforts to develop new detection concepts, such as the Total-Energy Detector with $\gamma$-ray imaging capability (i-TED). The latter is based on the simultaneous combination of Compton imaging with neutron time-of-flight (TOF) techniques, in order to achieve a superior level of sensitivity and selectivity in the measurement of stellar neutron capture rates., Comment: Nuclear Physics in Astrophysics IX - Conference Proceedings

Published
2019
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40. Development of a neutron imaging station at the n\_TOF facility of CERN and applications to beam intercepting devices

Author

Mingrone, Federica, Calviani, Marco, Martin, Claudio Torregrosa, Aberle, Oliver, Bacak, Michael, Chiaveri, Enrico, Fornasiere, Elvis, Perillo-Marcone, Antonio, and Vlachoudis, Vasilis

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment, Nuclear Experiment
Abstract

A neutron radiography testing station has been developed exploiting the neutron beam of CERN's n\_TOF Experimental Area 2, located at the shortest distance to the neutron producing-target. The characteristics of the n\_TOF neutron beam for the imaging setup are presented in this paper, together with the obtained experimental results. The possible developments of neutron imaging capabilities of the n\_TOF facility in terms of detection-systems and beam-line upgrades are as well outlined., Comment: 13 figures, 12 pages

Published
2019
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41. Measurement of the 235U(n,f) cross section relative to the 6Li(n,t) and 10B(n,alpha) standards from thermal to 170 keV neutron energy range at n_TOF

Author

Amaducci, S., Cosentino, L., Barbagallo, M., Colonna, N., Mengoni, A., Massimi, C., Meo, S. Lo, Finocchiaro, P., Aberle, O., Andrzejewski, J., Audouin, L., Bacak, M., Balibrea, J., Bečvář, F., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Cerutti, F., Chen, Y. H., Chiaveri, E., Cortés, G., Cortés-Giraldo, M. A., Damone, L. A., Diakaki, M., Domingo-Pardo, C., Dressler, R., Dupont, E., Durán, I., Fernández-Domínguez, B., Ferrari, A., Ferreira, P., Furman, V., Göbel, K., García, A. R., Gawlik, A., Gilardoni, S., Glodariu, T., Gonçalves, I. F., González-Romero, E., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Jericha, E., Käppeler, F., Kadi, Y., Kalamara, A., Kavrigin, P., Kimura, A., Kivel, N., Knapova, I., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Lederer, C., Leeb, H., Lerendegui-Marco, J., Lonsdale, S. J., Macina, D., Manna, A., Marganiec, J., Martínez, T., Masi, A., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Milazzo, P. M., Mingrone, F., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rauscher, T., Reifarth, R., Rubbia, C., Ryan, J. A., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sedyshev, P., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weiss, C., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Nuclear Experiment, High Energy Physics - Experiment
Abstract

The 235U(n,f) cross section was measured in a wide energy range at n_TOF relative to 6Li(n,t) and 10B(n,alpha), with high resolution and in a wide energy range, with a setup based on a stack of six samples and six silicon detectors placed in the neutron beam. This allowed us to make a direct comparison of the reaction yields under the same experimental conditions, and taking into account the forward/backward emission asymmetry. A hint of an anomaly in the 10{\div}30 keV neutron energy range had been previously observed in other experiments, indicating a cross section systematically lower by several percent relative to major evaluations. The present results indicate that the evaluated cross section in the 9{\div}18 keV neutron energy range is indeed overestimated, both in the recent updates of ENDF/B-VIII.0 and of the IAEA reference data. Furthermore, these new high-resolution data confirm the existence of resonance-like structures in the keV neutron energy region. The new, high accuracy results here reported may lead to a reduction of the uncertainty in the 1{\div}100 keV neutron energy region. Finally, the present data provide additional confidence on the recently re-evaluated cross section integral between 7.8 and 11 eV., Comment: 22 pages, 20 figures, submitted to PRC

Published
2019
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42. The Value of Tumour Markers in the Detection of Relapse—Lessons Learned from the Swiss Austrian German Testicular Cancer Cohort Study

Author

Stefanie Fischer, Christian Rothermundt, Odile Stalder, Angelika Terbuch, Thomas Hermanns, Deborah Zihler, Beat Müller, Christian D. Fankhauser, Anita Hirschi-Blickenstorfer, Bettina Seifert, Luis Alex Kluth, Mark-Peter Ufe, Walter Mingrone, Arnoud J. Templeton, Natalie Fischer, Sacha Rothschild, Regina Woelky, Silke Gillessen, and Richard Cathomas

Subjects
Testicular cancer follow-up, Tumour markers, Beta human chorionic gonadotropin, Alpha-fetoprotein, Lactate dehydrogenase, Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

The tumour markers alpha-fetoprotein (AFP), beta human chorionic gonadotropin (βHCG), and lactate dehydrogenase (LDH) have established roles in the management and follow-up of testicular cancer. While a tumour marker rise can serve as an indicator of relapse, the frequency of false-positive marker events has not been studied systematically in larger cohorts. We assessed the validity of serum tumour markers for the detection of relapse in the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS). This registry was set up to answer questions on the diagnostic performance and impact of imaging and laboratory tests in the management of testicular cancer, and has included 948 patients between January 2014 and July 2021.A total of 793 patients with a median follow-up of 29.0 mo were included. In total, 71 patients (8.9%) had a proven relapse, which was marker positive in 31 patients (43.6%). Of all patients, 124 (15.6%) had an event of a false-positive marker elevation. The positive predictive value (PPV) of the markers was limited, highest for βHCG (33.8%) and lowest for LDH (9.4%). PPV tended to increase with higher levels of elevation. These findings underline the limited accuracy of the conventional tumour markers to indicate or rule out a relapse. Especially, LDH as part of routine follow-up should be questioned. Patient summary: With the diagnosis of testicular cancer, the three tumour markers alpha-fetoprotein, beta human chorionic gonadotropin, and lactate dehydrogenase are routinely measured during follow-up to monitor for relapse. We demonstrate that these markers are often falsely elevated, and, by contrast, many patients do not have marker elevations despite a relapse. The results of this study can lead to improved use of these tumour markers during follow-up of testis cancer patients.

Published
2023
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43. Bariatric–metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial

Author

Verrastro, Ornella, Panunzi, Simona, Castagneto-Gissey, Lidia, De Gaetano, Andrea, Lembo, Erminia, Capristo, Esmeralda, Guidone, Caterina, Angelini, Giulia, Pennestrì, Francesco, Sessa, Luca, Vecchio, Fabio Maria, Riccardi, Laura, Zocco, Maria Assunta, Boskoski, Ivo, Casella-Mariolo, James R, Marini, Pierluigi, Pompili, Maurizio, Casella, Giovanni, Fiori, Enrico, Rubino, Francesco, Bornstein, Stefan R, Raffaelli, Marco, and Mingrone, Geltrude

Published
2023
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45. Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis

Author

Giulia Angelini, Lidia Castagneto-Gissey, Serenella Salinari, Alessandro Bertuzzi, Danila Anello, Meenakshi Pradhan, Marlen Zschätzsch, Paul Ritter, Carel W. Le Roux, Francesco Rubino, Nicola Basso, Giovanni Casella, Stefan R. Bornstein, Valentina Tremaroli, and Geltrude Mingrone

Subjects
Science
Abstract

High-fat diet (HFD) increases the risk of insulin resistance and non-alcoholic steatohepatitis (NASH). Here the authors report that the heat shock proteins HSP70 and GRP78 are increased in the jejunum of rats on HFD, and their continuous infusion leads insulin resistance and NASH, while in rats on a high-fat diet infused with monoclonal antibodies against HSP70 and GRP78 these phenotypes are reversed.

Published
2022
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46. Exploring the cost-effectiveness of high versus low perioperative fraction of inspired oxygen in the prevention of surgical site infections among abdominal surgery patients in three low- and middle-income countries

Author

Mwayi Kachapila, Mark Monahan, Adesoji O. Ademuyiwa, Yakubu Momohsani Adinoyi, Bruce M. Biccard, Christina George, Dhruva N. Ghosh, James Glasbey, Dion G. Morton, Osaheni Osayomwanbo, Rupert Pearse, Tracy E. Roberts, Atul Suroy, Saidu Yusuf Yakubu, Raymond Oppong, Aneel Bhangu, Maria Lorena Aguilera, Philip Alexander, Sara W. Al-Saqqa, Giuliano Borda-Luque, Ainhoa Costas-Chavarri, Thomas M. Drake, Faustin Ntirenganya, J. Edward Fitzgerald, Stuart J. Fergusson, J.C. Allen Ingabire, Lawani Ismaïl, Hosni Khairy Salem, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard Lilford, Andre L. Mihaljevic, Dion Morton, Alphonse Zeta Mutabazi, Dmitri Nepogodiev, Adewale O. Adisa, Riinu Ots, Francesco Pata, Thomas Pinkney, Tomas Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah Rayne, Catherine A. Shaw, Sebastian Shu, Richard Spence, Neil Smart, Stephen Tabiri, Ewen M. Harrison, Azmina Verjee, Emmy Runigamugabo, Chetan Khatri, Midhun Mohan, Zahra Jaffry, Afnan Altamini, Andrew Kirby, Kjetil Søreide, Gustavo Recinos, Jen Cornick, Maria Marta Modolo, Dushyant Iyer, Sebastian King, Tom Arthur, Sayeda Nazmum Nahar, Ade Waterman, Michael Walsh, Arnav Agarwal, Augusto Zani, Mohammed Firdouse, Tyler Rouse, Qinyang Liu, Juan Camilo Correa, Peep Talving, Mengistu Worku, Alexis Arnaud, Vassilis Kalles, Basant Kumar, Sunil Kumar, Radhian Amandito, Roy Quek, Luca Ansaloni, Ahmed Altibi, Donatas Venskutonis, Justas Zilinskas, Tomas Poskus, John Whitaker, Vanessa Msosa, Yong Yong Tew, Alexia Farrugia, Elaine Borg, Zineb Bentounsi, Tanzeela Gala, Ibrahim Al-Slaibi, Haya Tahboub, Osaid H. Alser, Diego Romani, Sebestian Shu, Piotr Major, Aurel Mironescu, Matei Bratu, Amar Kourdouli, Aliyu Ndajiwo, Abdulaziz Altwijri, Mohammed Ubaid Alsaggaf, Ahmad Gudal, Al Faifi Jubran, Sam Seisay, Bettina Lieske, Irene Ortega, Jenifa Jeyakumar, Kithsiri J. Senanayake, Omar Abdulbagi, Yucel Cengiz, Dmitri Raptis, Yuksel Altinel, Chia Kong, Ella Teasdale, Gareth Irwin, Michael Stoddart, Rakan Kabariti, Sukrit Suresh, Katherine Gash, Ragavan Narayanan, Mayaba Maimbo, Besmir Grizhja, Shpetim Ymeri, Gezim Galiqi, Roberto Klappenbach, Diego Antezana, Alvaro Enrique Mendoza Beleño, Cecilia Costa, Belen Sanchez, Susan Aviles, Claudio Gabriel Fermani, Rubén Balmaceda, Santiago Villalobos, Juan Manuel Carmona, Daniel Hamill, Peter Deutschmann, Simone Sandler, Daniel Cox, Ram Nataraja, Claire Sharpin, Damir Ljuhar, Demi Gray, Morgan Haines, Dush Iyer, Nithya Niranjan, Scott D'Amours, Morvarid Ashtari, Helena Franco, Ashrarur Rahman Mitul, Sabbir Karim, Nowrin F. Aman, Mahnuma Mahfuz Estee, Umme Salma, Joyeta Razzaque, Tasnia Hamid Kanta, Sayeeda Aktar Tori, Shadid Alamin, Swapnil Roy, Shadid Al Amin, Rezaul Karim, Muhtarima Haque, Amreen Faruq, Farhana Iftekhar, Margaret O'Shea, Greg Padmore, Ramesh Jonnalagadda, Andrey Litvin, Aliaksandr Filatau, Dzmitry Paulouski, Maryna Shubianok, Tatsiana Shachykava, Dzianis Khokha, Vladimir Khokha, Fernande Djivoh, Francis Dossou, Djifid Morel Seto, Dansou Gaspard Gbessi, Bruno Noukpozounkou, Yacoubou Imorou Souaibou, Kpèmahouton René Keke, Fred Hodonou, Ernest Yemalin Stephane Ahounou, Thierry Alihonou, Max Dénakpo, Germain Ahlonsou, Alemayehu Ginbo Bedada, Carlos Nsengiyumva, Sandrine Kwizera, Venerand Barendegere, Philip Choi, Simon Stock, Luai Jamal, Georges Azzie, Sameer Kushwaha, Tzu-Ling Chen, Chingwan Yip, Irene Montes, Felipe Zapata, Sebastian Sierra, Maria Isabel Villegas Lanau, Maria Clara Mendoza Arango, Ivan Mendoza Restrepo, Ruben Santiago Restrepo Giraldo, Edgar Domini, Robert Karlo, Jakov Mihanovic, Mohamed Youssef, Hossam Elfeki, Waleed Thabet, Aly Sanad, Gehad Tawfik, Ahmed Zaki, Noran Abdel-Hameed, Mohamed Mostafa, Muhammad Fathi Waleed Omar, Ahmed Ghanem, Emad Abdallah, Adel Denewar, Eman Emara, Eman Rashad, Ahmad Sakr, Rehab Elashry, Sameh Emile, Toqa Khafagy, Sara Elhamouly, Arwa Elfarargy, Amna Mamdouh Mohamed, Ghada Saied Nagy, Abeer Esam, Eman Elwy, Aya Hammad, Salwa Khallaf, Eman Ibrahim, Ahmed Saidbadr, Ahmed Moustafa, Amany Eldosouky Mohammed, Mohammed Elgheriany, Eman Abdelmageed, Eman Abd Al Raouf, Esraa Samir Elbanby, Maha Elmasry, Mahitab Morsy Farahat, Eman Yahya Mansor, Eman Magdy Hegazy, Esraa Gamal, Heba Gamal, Hend Kandil, Doaa Maher Abdelrouf, Mohamed Moaty, Dina Gamal, Nada El-Sagheer, Mohamed Salah, Salma Magdy, Asmaa Salah, Ahmed Essam, Ahmed Ali, Mahmoud Badawy, Sara Ahmed, Mazed Mohamed, Abdelrahman Assal, Mohamed Sleem, Mai Ebidy, Aly Abd Elrazek, Diaaaldin Zahran, Nourhan Adam, Mohamed Nazir, Adel B. Hassanein, Ahmed Ismail, Amira Elsawy, Rana Mamdouh, Mohamed Mabrouk, Lopna Ahmed Mohamed Ahmed, Mohamed Hassab Alnaby, Eman Magdy, Manar Abd-Elmawla, Marwan Fahim, Bassant Mowafy, Moustafa Ibrahim Mahmoud, Meran Allam, Muhammad Alkelani, Noran Halim El Gendy, Mariam Saad Aboul-Naga, Reham Alaa El-Din, Alyaa Halim Elgendy, Mohamed Ismail, Mahmoud Shalaby, Aya Adel Elsharkawy, Mahmoud Elsayed Moghazy, Khaled Hesham Elbisomy, Hend Adel Gawad Shakshouk, Mohamed Fouad Hamed, Mai Mohamed Ebidy, Mostafa Abdelkader, Mohamed Karkeet, Hayam Ahmed, Israa Adel, Mohammad Elsayed Omar, Mohamed Ibrahim, Omar Ghoneim, Omar Hesham, Shimaa Gamal, Karim Hilal, Omar Arafa, Sawsan Adel Awad, Menatalla Salem, Fawzia Abdellatif Elsherif, Nourhan Elsabbagh, Moustafa R. Aboelsoud, Ahmed Hossam Eldin Fouad Rida, Amr Hossameldin, Ethar Hany, Yomna Hosny Asar, Nourhan Anwar, Mohamed Gadelkarim, Samar Abdelhady, Eman Mohamed Morshedy, Reham Saad, Nourhan Soliman, Mahmoud Salama, Eslam Ezzat, Arwa Mohamed, Arwa Ibrahim, Alaa Fergany, Sara Mohammed, Aya Reda, Yomna Allam, Hanan Adel Saad, Afnan Abdelfatah, Aya Mohamed Fathy, Ahmed El-Sehily, Esraa Abdalmageed Kasem, Ahmed Tarek Abdelbaset Hassan, Ahmed Rabeih Mohammed, Abdalla Gamal Saad, Yasmin Elfouly, Nesma Elfouly, Arij Ibrahim, Amr Hassaan, Mohammed Mustafa Mohammed, Ghada Elhoseny, Mohamed Magdy, Esraa Abd Elkhalek, Yehia Zakaria, Tarek Ezzat, Ali Abo El Dahab, Mohamed Kelany, Sara Arafa, Osama Mokhtar Mohamed Hassan, Nermin Mohamed Badwi, Ahmad Saber Sleem, Hussien Ahmed, Kholoud Abdelbadeai, Mohamed Abozed Abdullah, Muhammad Amsyar Auni Lokman, Suraya Bahar, Anan Rady Abdelazeam, Abdelrahman Adelshone, Muhammad Bin Hasnan, Athirah Zulkifli, Siti Nur Alia Kamarulzamil, Abdelaziz Elhendawy, Aliang Latif, Ahmad Bin Adnan, Shahadatul Shaharuddin, Aminah Hanum Haji Abdul Majid, Mahmoud Amreia, Dina Al-Marakby, Mahmoud Salma, Mohamad Jeffrey Bin Ismail, Elissa Rifhan Mohd Basir, Citra Dewi, Mohd Ali, Aya Yehia Ata, Maha Nasr, Asmaa Rezq, Ahmed Sheta, Sherif Tariq, Abd Elkhalek Sallam, Abdelrhman K.Z. Darwish, Sohaila Elmihy, Shady Elhadry, Ahmed Farag, Haidar Hajeh, Abdelaziz Abdelaal, Amro Aglan, Ahmed Zohair, Mahitab Essam, Omar Moussa, Esraa El-Gizawy, Mostafa Samy, Safia Ali, Esraa Elhalawany, Ahmed Ata, Mohamed El Halawany, Mohamed Nashat, Samar Soliman, Alaa Elazab, Mostada Samy, Mohamed A. Abdelaziz, Khaled Ibrahim, Ahmed mohamed Ibrahim, Ammar Gado, Usama Hantour, Esraa Alm Eldeen, Mohamed Reda loaloa, Arwa Abouzaid, Mostafa Ahmed Bahaa Eldin, Eman Hashad, Fathy Sroor, Doaa Gamil, Eman Mahmoud Abdulhakeem, Mahmoud Zakaria, Fawzy Mohamed, Marwan Abubakr, Elsayed Ali, Hesham Magdy, Menna Tallah Ramadan, Mohamed Abdelaty Mohamed, Salma Mansour, Hager Abdul Aziz Amin, Ahmed Rabie Mohamed, Mahmoud Saami, Nada Ahmed Reda Elsayed, Adham Tarek, Sabry Mohy Eldeen Mahmoud, Islam Magdy El Sayed, Amira Reda, Martina Yusuf Shawky, Mohammed Mousa Salem, Shahinaz Alaa El-Din, Noha Abdullah Soliman, Muhammed Talaat, Shahinaz Alaael-Dein, Ahmed Abd Elmoen Elhusseiny, Noha Abdullah, Mohammed Elshaar, Aya AbdelFatah Ibraheem, Hager Abdulaziz, Mohammed Kamal Ismail, Mona Hamdy Madkor, Mohamed Abdelaty, Sara Mahmoud Abdel-Kader, Osama Mohamed Salah, Mahmoud Eldafrawy, Ahmed Zaki Eldeeb, Mostafa Mahmoud Eid, Attia Attia, Khalid Salah El-Dien, Ayman Shwky, Mohamed Adel Badenjki, Abdelrahman Soliman, Samaa Mahmoud Al Attar, Farrag Sayed, Fahd Abdel Sabour, Mohammed G. Azizeldine, Muhammad Shawqi, Abdullah Hashim, Ahmed Aamer, Ahmed Mahmoud Abdelraouf, Mahmoud Abdelshakour, Amal Ibrahim, Basma Mahmoud, Mohamed Ali Mahmoud, Mostafa Qenawy, Ahmed M. Rashed, Ahmed Dahy, Marwa Sayed, Ahmed W. Shamsedine, Bakeer Mohamed, Ahmad Hasan, Mahmoud M. Saad, Khalil Abdul Bassit, Nadia Khalid Abd El-Latif, Nada Elzahed, Ahmed El Kashash, Nada Mohamed Bekhet, Sarah Hafez, Ahmed Gad, Mahmoud Elkhadragy Maher, Ahmed Abd Elsameea, Mohamed Hafez, Ahmad Sabe, Ataa Ahmed, Ahmed Shahine, Khaled Dawood, Shireen Gaafar, Reem Husseiny, Omnia Aboelmagd, Ahmed Soliman, Nourhan Mesbah, Hossam Emadeldin, Amgad Al Meligy, Amira Hassan Bekhet, Doaa Hasan, Khaled Alhady, Ahmad Khaled Sabe, Mahmoud A. Elnajjar, Majed Aboelella, Ward Hamsho, Ihab Hassan, Hala Saad, Galaleldin Abdelazim, Hend Mahmoud, Noha Wael, Ahmedali M. Kandil, Ahmed Magdy, Shimaa Said Elkholy, Badr Eldin Adel, Kareem Dabbour, Saged Elsherbiney, Omar Mattar, Abdulshafi Khaled Abdrabou, Mohammed Yahia Mohamed Aly, Abdelrahman Geuoshy, Ahmedglal Elnagar, Saraibrahim Ahmed, Ibrahem Abdelmotaleb, Amr Ahmed Saleh, Manar Saeed, Shady Mahmoud, Badreldin Adel Tawfik, Samar Adel Ismail, Esraay Zakaria, Mariam O. Gad, Mohamed Salah Elhelbawy, Monica Bassem, Noha Maraie, Nourhan Medhat Elhadary, Nourhan Semeda, Shaza Rabie Mohamed, Hesham Mohammed Bakry, A.A. Essam, Dina Tarek, Khlood Ashour, Alaa Elhadad, Abdulrahman Abdel-Aty, Ibrahim Rakha, Sara Mamdouh Matter, Rasha Abdelhamed, Omar Abdelkader, Ayat Hassaan, Yasmin Soliman, Amna Mohamed, Sara Ghanem, Sara Amr Mohamed Farouk, Eman Mohamed Ibrahim, Esraa El-Taher, Merna Mostafa, Mohamed Fawzy Mahrous Badr, Rofida Elsemelawy, Aya El-Sawy, Ahmad Bakr, Ahmad Abdel Razaq Al Rafati, Sten Saar, Arvo Reinsoo, Nebyou Seyoum, Tewodros Worku, Agazi Fitsum, Matti Tolonen, Ari Leppäniemi, Ville Sallinen, Benoît Parmentier, Matthieu Peycelon, Sabine Irtan, Sabrina Dardenne, Elsa Robert, Betty Maillot, Etienne Courboin, Alexis Pierre Arnaud, Juliette Hascoet, Olivier Abbo, Amir Ait Kaci, Thomas Prudhomme, Quentin Ballouhey, Céline Grosos, Laurent Fourcade, Tolg Cecilia, Colombani Jean-Francois, Francois-Coridon Helene, Xavier Delforge, Elodie Haraux, Bertrand Dousset, Roberto Schiavone, Sebastien Gaujoux, Jean-Baptiste Marret, Aurore Haffreingue, Julien Rod, Mariette Renaux-Petel, Jean-François Lecompte, Jean Bréaud, Pauline Gastaldi, Chouikh Taieb, Raquillet Claire, Echaieb Anis, Nasir Bustangi, Manuel Lopezv, Aurelien Scalabre, Maria Giovanna Grella, Aurora Mariani, Guillaume Podevin, Françoise Schmitt, Erik Hervieux, Aline Broch, Cecile Muller, Dickson Bandoh, Francis Abantanga, Martin Kyereh, Hamza Asumah, Eric Kofi Appiah, Paul Wondoh, Adam Gyedu, Charles Dally, Kwabena Agbedinu, Michael Amoah, Abiboye Yifieyeh, Frank Owusu, Mabel Amoako-Boateng, Makafui Dayie, Richmond Hagan, Sam Debrah, Micheal Ohene-Yeboah, Joe-Nat Clegg-Lampety, Victor Etwire, Jonathan Dakubo, Samuel Essoun, William Bonney, Hope Glover-Addy, Samuel Osei-Nketiah, Joachim Amoako, Niiarmah Adu-Aryee, William Appeadu-Mensah, Antoinette Bediako-Bowan, Florence Dedey, Mattew Ekow, Emmanuel Akatibo, Musah Yakubu, Hope Edem Kofi Kordorwu, Kwasi Asare-Bediako, Enoch Tackie, Kenneth Aaniana, Emmanuel Acquah, Richard Opoku-Agyeman, Anthony Avoka, Kwasi Kusi, Kwame Maison, Frank Enoch Gyamfi, Gandau Naa Barnabas, Saiba Abdul-Latif, Philip Taah Amoako, Anthony Davor, Victor Dassah, Enoch Dagoe, Prince Kwakyeafriyie, Elliot Akoto, Eric Ackom, Ekow Mensah, Ebenezer Takyi Atkins, Christian Lari Coompson, Nikolaos Ivros, Christoforos Ferousis, Vasileios Kalles, Christos Agalianos, Ioannis Kyriazanos, Christos Barkolias, Angelos Tselos, Georgios Tzikos, Evangelos Voulgaris, Dimitrios Lytras, Athanasia Bamicha, Kyriakos Psarianos, Anastasios Stefanopoulos, Ioannis Patoulias, Dimitrios Sfougaris, Ioannis Valioulis, Dimitrios Balalis, Dimitrios Korkolis, Dimitrios K. Manatakis, Georgios Kyrou, Georgios Karabelias, Iason-Antonios Papaskarlatos, Kolonia Konstantina, Nikolaos Zampitis, Stylianos Germanos, Aspasia Papailia, Theodosios Theodosopoulos, Georgios Gkiokas, Magdalini Mitroudi, Christina Panteli, Thomas Feidantsis, Konstantinos Farmakis, Dimitrios Kyziridis, Orestis Ioannidis, Styliani Parpoudi, Georgios Gemenetzis, Stavros Parasyris, Christos Anthoulakis, Nikolaos Nikoloudis, Michail Margaritis, Maria-Lorena Aguilera-Arevalo, Otto Coyoy-Gaitan, Javier Rosales, Luis Tale, Rafael Soley, Emmanuel Barrios, Servio Tulio Torres Rodriguez, Carlos Paz Galvez, Danilo Herrera Cruz, Guillermo Sanchez Rosenberg, Alejandro Matheu, David Monterroso Cohen, Marie Paul, Angeline Charles, Justin Chak Yiu Lam, Man Hon Andrew Yeung, Chi Ying Jacquelyn Fok, Ka Hin Gabriel Li, Anthony Chuk-Him Lai, Yuk Hong Eric Cheung, Hong Yee Wong, Ka Wai Leung, Tien Seng Bryan Lee, Wai Him Lam, Weihei Dao, Stephanie Hiu-wai Kwok, Tsz-Yan Katie Chan, Yung Kok Ng, T.W.C. Mak, Chi Chung Foo, James Yang, Ankur Bhatnagar, Vijaid Upadhyaya, Uday Muddebihal, Wasim Dar, K.C. Janardha, Neerav Aruldas, Fidelis Jacklyn Adella, Anthonius Santoso Rulie, Ferdy Iskandar, Jonny Setiawan, Cicilia Viany Evajelista, Hani Natalie, Arlindawati Suyadi, Rudy Gunawan, Herlin Karismaningtyas, Lusi Padma Sulistianingsih Mata, Ferry Fitriya Ayu Andika, Afifatun Hasanah, T. Ariani Widiastini, Nurlaila Ayu Purwaningsih, Annisa Dewi Fitriana Mukin, Dina Faizatur Rahmah, Hazmi Dwinanda Nurqistan, Hasbi Maulana Arsyad, Novia Adhitama, Wifanto Saditya Jeo, Nathania Sutandi, Audrey Clarissa, Phebe Anggita Gultom, Matthew Billy, Andreass Haloho, Nadya Johanna, Felix Lee, Radin Mohd Nurrahman Radin Dorani, Martha Glynn, Mohammad Alherz, Wennweoi Goh, Haaris A. Shiwani, Lorraine Sproule, Kevin C. Conlon, Miklosh Bala, Asaf Kedar, Luca Turati, Federica Bianco, Francesca Steccanella, Gaetano Gallo, Mario Trompetto, Giuseppe Clerico, Matteo Papandrea, Giuseppe Sammarco, Rosario Sacco, Angelo Benevento, Luisa Giavarini, Mariano Cesare Giglio, Luigi Bucci, Gianluca Pagano, Viviana Sollazzo, Roberto Peltrini, Gaetano Luglio, Arianna Birindelli, Salomone Di Saverio, Gregorio Tugnoli, Miguel Angel Paludi, Pietro Mingrone, Domenica Pata, Francesco Selvaggi, Lucio Selvaggi, Gianluca Pellino, Natale Di Martino, Gianluca Curletti, Paolo Aonzo, Raffaele Galleano, Stefano Berti, Elisa Francone, Silvia Boni, Laura Lorenzon, Annalisa lo Conte, Genoveffa Balducci, Gianmaria Confalonieri, Giovanni Pesenti, Laura Gavagna, Giorgio Vasquez, Simone Targa, Savino Occhionorelli, Dario Andreotti, Giacomo Pata, Andrea Armellini, Deborah Chiesa, Fabrizio Aquilino, Nicola Chetta, Arcangelo Picciariello, Mohamed Abdelkhalek, Andrea Belli, Silvia De Franciscis, Annamaria Bigaran, Alessandro Favero, Stefano M.M. Basso, Paola Salusso, Martina Perino, Sylvie Mochet, Diego Sasia, Francesco Riente, Marco Migliore, David Merlini, Silvia Basilicò, Carlo Corbellini, Veronica Lazzari, Yuri Macchitella, Luigi Bonavina, Daniele Angelieri, Diego Coletta, Federica Falaschi, Marco Catani, Claudia Reali, Mariastella Malavenda, Celeste Del Basso, Sergio Ribaldi, Massimo Coletti, Andrea Natili, Norma Depalma, Immacolata Iannone, Angelo Antoniozzi, Davide Rossi, Daniele Gui, Gerardo Perrotta, Matteo Ripa, Francesco Ruben Giardino, Maurizio Foco, Erika Vicario, Federico Coccolini, Gabriela Elisa Nita, Nicoletta Leone, Andrea Bondurri, Anna Maffioli, Andrea Simioni, Davide De Boni, Sandro Pasquali, Elena Goldin, Elena Vendramin, Eleonora Ciccioli, Umberto Tedeschi, Luca Bortolasi, Paola Violi, Tommaso Campagnaro, Simone Conci, Giovanni Lazzari, Calogero Iacono, Alfredo Gulielmi, Serena Manfreda, Anna Rinaldi, Maria Novella Ringressi, Beatrice Brunoni, Giuseppe Salamone, Mirko Mangiapane, Paolino De Marco, Antonella La Brocca, Roberta Tutino, Vania Silvestri, Leo Licari, Tommaso Fontana, Nicolò Falco, Gianfranco Cocorullo, Mostafa Shalaby, Pierpaolo Sileri, Claudio Arcudi, Isam Bsisu, Khaled Aljboor, Lana Abusalem, Aseel Alnusairat, Ahmad Qaissieh, Emad Al-Dakka, Ali Ababneh, Oday Halhouli, Taha Yusufali, Hussein Mohammed, Justus Lando, Robert Parker, Wairimu Ndegwa, Mantas Jokubauskas, Jolanta Gribauskaite, Justas Kuliavas, Audrius Dulskas, Narimantas E. Samalavicius, Kristijonas Jasaitis, Audrius Parseliunas, Viktorija Nevieraite, Margarita Montrimaite, Evelina Slapelyte, Edvinas Dainius, Romualdas Riauka, Zilvinas Dambrauskas, Andrejus Subocius, Linas Venclauskas, Antanas Gulbinas, Saulius Bradulskis, Simona Kasputyte, Deimante Mikuckyte, Mindaugas Kiudelis, Tomas Jankus, Steponas Petrikenas, Matas Pažuskis, Zigmantas Urniežius, Mantas Vilčinskas, Vincas Jonas Banaitis, Vytautas Gaižauskas, Edvard Grisin, Povilas Mazrimas, Rokas Rackauskas, Mantas Drungilas, Karolis Lagunavicius, Vytautas Lipnickas, Dovilè Majauskyté, Valdemaras Jotautas, Tomas Abaliksta, Laimonas Uščinas, Gintaras Simutis, Adomas Ladukas, Donatas Danys, Erikas Laugzemys, Saulius Mikalauskas, Elena Zdanyte Sruogiene, Petras Višinskas, Reda Žilinskienė, Deividas Dragatas, Andrius Burmistrovas, Zygimantas Tverskis, Arturas Vaicius, Ruta Mazelyte, Antanas Zadoroznas, Nerijus Kaselis, Greta Žiubrytė, Finaritra Casimir Fleur Prudence Rahantasoa, Luc Hervé Samison, Fanjandrainy Rasoaherinomenjanahary, Todisoa Emmanuella Christina Tolotra, Cornelius Mukuzunga, Chimwemwe Kwatiwani, Nelson Msiska, Feng Yih Chai, Siti Mohd Desa Asilah, Khuzaimah Zahid Syibrah, Pui Xin Chin, Afizah Salleh, Nur Zulaika Riswan, April Camilla Roslani, Hoong-Yin Chong, Nora Abdul Aziz, Keat-Seong Poh, Chu-Ann Chai, Sandip Kumar, Mustafa Mohammed Taher, Nik Ritza Kosai, Dayang Nita Abdul Aziz, Reynu Rajan, Rokayah Julaihi, Durvesh Lacthman Jethwani, Muhammad Taqiyuddin Yahaya, Nik Azim Nik Abdullah, Susan Wndy Mathew, Kuet Jun Chung, Milaksh Kumar Nirumal, R. Goh Ern Tze, Syed Abdul Wahhab Eusoffee Wan Ali, Yiing Yee Gan, Jesse Ron Swire Ting, Samuel S.Y. Sii, Kean Leong Koay, Yi Koon Tan, Alvin Ee Zhiun Cheah, Chui Yee Wong, Tuan Nur'Azmah Tuan Mat, Crystal Yern Nee Chow, Prisca A.L. Har, Yishan Der, Fitjerald Henry, Xinwei Low, Ya Theng Neo, Hian Ee Heng, Shu Ning Kong, Cheewei Gan, Yi Ting Mok, Yee Wen Tan, Kandasami Palayan, Mahadevan Deva Tata, Yih Jeng Cheong, Kuhaendran Gunaseelan, Wan Nurul 'Ain Wan Mohd Nasir, Pigeneswaren Yoganathan, Eu Xian Lee, Jian Er Saw, Li Jing Yeang, Pei Ying Koh, Shyang Yee Lim, Shuang Yi Teo, Nicole Grech, Daniela Magri, Kristina Cassar, Christine Mizzi, Malcolm Falzon, Nihaal Shaikh, Ruth Scicluna, Stefan Zammit, Sean Mizzi, Svetlana Doris Brincat, Thelma Tembo, Vu Thanh Hien Le, Tara Grima, Keith Sammut, Kurt Carabott, Ciskje Zarb, Andre Navarro, Thea Dimech, Georgette Marie Camilleri, Isaac Bertuello, Jeffrey Dalli, Karl Bonavia, Samantha Corro-Diaz, Marisol Manriquez-Reyes, Amina Abdelhamid, Abdelmalek Hrora, Sarah Benammi, Houda Bachri, Meryem Abbouch, Khaoula Boukhal, Redouane Mammar Bennai, Abdelkader Belkouchi, Mohamed Sobhi Jabal, Chaymae Benyaiche, Maarten Vermaas, Lucia Duinhouwer, Javier Pastora, Greta Wood, Maria Soledad Merlo, Akinlabi Ajao, Omobolaji Ayandipo, Taiwo Lawal, Abdussemiu Abdurrazzaaq, Muslimat Alada, Abdulrasheed Nasir, James Adeniran, Olufemi Habeeb, Ademola Popoola, Ademola Adeyeye, Ademola Adebanjo, Opeoluwa Adesanya, Adewale Adeniyi, Henry Mendel, Bashir Bello, Umar Muktar, Adedapo Osinowo, Thomas Olagboyega Olajide, Oyindamola Oshati, George Ihediwa, Babajide Adenekan, Victor Nwinee, Felix Alakaloko, Adesoji Ademuyiwa, Olumide Elebute, Abdulrazzaq Lawal, Chris Bode, Mojolaoluwa Olugbemi, Alaba Adesina, Olubukola Faturoti, Oluwatomi Odutola, Oluwaseyi Adebola, Clement Onuoha, Ogechukwu Taiwo, Omolara Williams, Fatai Balogun, Olalekan Ajai, Mobolaji Oludara, Iloba Njokanma, Roland Osuoji, Stephen Kache, Jonathan Ajah, Jerry Makama, Ahmed Adamu, Suleiman Baba, Mohammad Aliyu, Shamsudeen Aliyu, Yahaya Ukwenya, Halima Aliyu, Tunde Sholadoye, Muhammad Daniyan, Oluseyi Ogunsua, Lofty-John Anyanwu, Abdurrahaman Sheshe, Aminu Mohammad, Samson Olori, Philip Mshelbwala, Babatunde Odeyemi, Garba Samson, Oyediran Kehinde Timothy, Sani Ali Samuel, Anthony Ajiboye, Isaac Amole, Olajide Abiola, Akin Olaolorun, Torhild Veen, Arezo Kanani, Kristian Styles, Ragnar Herikstad, Johannes Wiik Larsen, Jon Arne Søreide, Elisabeth Jensen, Mads Gran, Eirik Kjus Aahlin, Tina Gaarder, Peter Wiel Monrad-Hansen, Pål Aksel Næss, Giedrius Lauzikas, Joachim Wiborg, Silje Holte, Knut Magne Augestad, Gurpreet Singh Banipal, Michela Monteleone, Thomas Tetens Moe, Johannes Kurt Schultz, Taher Al-Taher, Ayah Hamdan, Ayman Salman, Rana Saadeh, Aseel Musleh, Dana Jaradat, Soha Abushamleh, Sakhaa Hanoun, Amjad Abu Qumbos, Aseel Hamarshi, Ayman, Taher, Israa Qawasmi, Khalid Qurie, Marwa Altarayra, Mohammad Ghannam, Alaa Shaheen, Azher Herebat, Aram Abdelhaq, Ahmad Shalabi, Maram Abu-Toyour, Fatema Asi, Ala Shamasneh, Anwar Atiyeh, Mousa Mustafa, Rula Zaa'treh, Majd Dabboor, Enas Alaloul, Heba Baraka, Jehad Meqbil, Alaa Al-Buhaisi, Mohamedraed Elshami, Samah Afana, Sahar Jaber, Said Alyacoubi, Yousef Abuowda, Tasneem Idress, Eman Abuqwaider, Sara Al-Saqqa, Alaa Bowabsak, Alaa El Jamassi, Doaa Hasanain, Hadeel Al-Farram, Maram Salah, Aya Firwana, Marwa Hamdan, Israa Awad, Ahmad Ashour, Fayez Elian Al Barrawi, Ahmed Al-Khatib, Maha Al-Faqawi, Mohamed Fares, Amjad Elmashala, Mohammad Adawi, Ihdaa Adawi, Reem Khreishi, Rose Khreishi, Ahed Ghaben, Najwa Nadeem, Muhammad Saqlain, Jibran Abbasy, Abdul Rehman Alvi, Noman Shahzad, Kamran Faisal Bhopal, Zainab Iftikhar, Muhammad Talha Butt, Syed Asaat Ul Razi, Asdaq Ahmed, Ali Khan Niazi, Ibrahim Raza, Fatima Baluch, Ahmed Raza, Ahmad Bani-Sadar, Muhammad Adil, Awais Raza, Mahnoor Javaid, Muhammad Waqar, Maryam Ali Khan, Mohammad Mohsin Arshad, Mohammadasim Amjad, Gustavo Miguel Machain Vega, Jorge Torres Cardozo, Marcelo O´Higgins Roche, Gustavo Rodolfo Pertersen Servin, Helmut Alfredo Segovia Lohse, Larissa Ines Páez Lopez, Ramón Augusto Melo Cardozo, Fernando Espinoza, Angel David Pérez Rojas, Diana Sanchez, Camila Sanchez Samaniego, Shalon Guevara Torres, Alexander Canta Calua, Cesar Razuri, Nadia Ortiz, Xianelle Rodriguez, Nahilia Carrasco, Fridiz Saravia, Hector Shibao Miyasato, María Valcarcel-Saldaña, Ysabel Esthefany Alejos Bermúdez, Juan Carpio, Walter Ruiz Panez, Pedro Angel Toribio Orbegozo, Carolina Guzmán Dueñas, Kevin Turpo Espinoza, Ana Maria Sandoval Barrantes, Jorge Armando Chungui Bravo, Lorena Fuentes-Rivera, Carmen Fernández, Bárbara Málaga, Joselyn Ye, Ricardo Velasquez, Jannin Salcedo, Ana Lucia Contreras-Vergara, Angelica Genoveva Vergara Mejia, Maria Soledad Gonzales Montejo, Marilia Del Carmen Escalante Salas, Willy Alcca Ticona, Marvin Vargas, George Christian Manrique Sila, Robinson Mas, Arazzelly del Pilar Paucar, Armando José Román Velásquez, Alina Robledo-Rabanal, Ludwing Alexander Zeta Solis, Kenny Turpo Espinoza, José Luis Hamasaki Hamaguchi, Erick Samuel Florez Farfan, Linda Alvi Madrid Barrientos, Juan Jaime Herrera Matta, John Jemuel V. Mora, Menold Archee P. Redota, Manuel Francisco Roxas, Maria Jesusa B. Maño, Marie Dione Parreno-Sacdalan, Christel Leanne Almanon, Maciej Walędziak, Rafał Roszkowski, Michał Janik, Anna Lasek, Dorota Radkowiak, Mateusz Rubinkiewicz, Cristina Fernandes, Jose Costa-Maia, Renato Melo, Liviu Muntean, Aurel Sandu Mironescu, Lucian Corneliu Vida, Mariuca Popa, Hogea Mircea, Mihaela Vartic, Bogdan Diaconescu, Matei Razvan Bratu, Ionut Negoi, Mircea Beuran, Cezar Ciubotaru, Norbert Uzabumwana, Dieudonne Duhoranenayo, Elio Jovine, Nicola Zanini, Giovanni Landolfo, Murad Aljiffry, Faisal Idris, Mohammed Saleh A. Alghamdi, Ashraf Maghrabi, Abdulmalik Altaf, Aroub Alkaaki, Ahmad Khoja, Abrar Nawawi, Sondos Turkustani, Eyad Khalifah, Adel Albiety, Sarah Sahel, Reham Alshareef, Mohammed Najjar, Ahmed Alzahrani, Ahmed Alghamdi, Wedyan Alhazmi, Ghiath Al Saied, Mohammed Alamoudi, Muhammed Masood Riaz, Mazen Hassanain, Basmah Alhassan, Abdullah Altamimi, Reem Alyahya, Norah Al Subaie, Fatema Al Bastawis, Afnan Altamimi, Thamer Nouh, Roaa Khan, Milan Radojkovic, Ljiljana Jeremic, Milica Nestorovic, Jia Hao Law, Keith Say Kwang Tan, Ryan Choon Kiat Tan, Joel Kin Tan, Lau Wen Liang Joel, Xue Wei Chan, Faith Qi Hui Leong, Choon Seng Chong, Sharon Koh, Kai Yin Lee, Kuok Chung Lee, Kent Pluke, Britta Dedekind, Puyearashid Nashidengo, Mark Ian Hampton, Johanna Joosten, Sanju Sobnach, Liana Roodt, Anthony Sander, James Pape, Niveshni Maistry, Phumudzo Ndwambi, Kamau Kinandu, Myint Tun, Frederick Du Toit, Quinn Ellison, D.C. Grobler, Sule Burger, Lawrence Bongani Khulu, Rachel Moore, Vicky Jennings, Astrid Leusink, Nazmie Kariem, Juan Gouws, Kathryn Chu, Heather Bougard, Fazlin Noor, Angela Dell, Stephanie Van Straten, Arvin Khamajeet, Serge Kapenda Tshisola, Kalangu Kabongo, Victor Kong, Yoshan Moodley, Frank Anderson, Thandinkosi Madiba, Flip du Plooy, Leila Hartford, Gareth Chilton, Parveen Karjiker, Matlou Ernest Mabitsela, Sibongile Ruth Ndlovu, Maria Badicel, Robert Jaich, Jaime Ruiz-Tovar, Luis Garcia-Florez, Jorge L. Otero-Díez, Virginia Ramos Pérez, Nuria Aguado Suárez, Javier Minguez García, Sara Corral Moreno, Maria Vicenta Collado, Virginia Jiménez Carneros, Javier García Septiem, Mariana Gonzalez, Antonio Picardo, Enrique Esteban, Esther Ferrero, Eloy Espin-Basany, Ruth Blanco-Colino, Valeria Andriola, Lorena Solar García, Elisa Contreras, Carmen García Bernardo, Janet Pagnozzi, Sandra Sanz, Alberto Miyar de León, Asnel Dorismé, Joseluis Rodicio, Aida Suarez, Jessica Stuva, Tamara Diaz Vico, Laura Fernandez-Vega, Carla Soldevila-Verdeguer, Fatima Sena-Ruiz, Natalia Pujol-Cano, Paula Diaz-Jover, José Maria Garcia-Perez, Juan Jose Segura-Sampedro, Cristina Pineño-Flores, David Ambrona-Zafra, Andrea Craus-Miguel, Patricia Jimenez-Morillas, Angela Mazzella, A.B. Jayathilake, S.P.B. Thalgaspitiya, L.S. Wijayarathna, P.M.S.N. Wimalge, Hakeem Ayomi Sanni, Ogheneochuko Okenabirhie, Anmar Homeida, Abobaker Younis, Omer Abdelbagi Omer, Mustafa Abdulaziz, Ali Mussad, Ali Adam, Ida Björklund, Sandra Ahlqvist, Anders Thorell, Fredrik Wogensen, Arestis Sokratous, Michaela Breistrand, Hildur Thorarinsdottir, Johanna Sigurdadottir, Maziar Nikberg, Abbas Chabok, Maria Hjertberg, Peter Elbe, Deborah Saraste, Wiktor Rutkowski, Louise Forlin, Karoliina Niska, Malin Sund, Dennis Oswald, Georgios Peros, Rafael Bluelle, Katharina Reinisch, Daniel Frey, Adrian Palma, Dimitri Aristotle Raptis, Lucius Zumbühl, Markus Zuber, Roger Schmid, Gabriela Werder, Antonio Nocito, Alexandra Gerosa, Silke Mahanty, Lukas Werner Widmer, Julia Müller, Alissa Gübeli, Grzegorz Zuk, Osman Bilgin Gulcicek, Talar Vartanoglu, Emin Kose, Servet Rustu Karahan, Mehmet Can Aydin, Nuri Alper Sahbaz, Ilkay Halicioglu, Halil Alis, Ipek Sapci, Can Adıyaman, Ahmet Murat Pektaş, Turgut Bora Cengiz, Ilkan Tansoker, Vedatcan Işler, Muazzez Cevik, Deniz Mutlu, Volkan Ozben, Berk Baris Ozmen, Sefa Bayram, Sinem Yolcu, Berna Buse Kobal, Ömer Faruk Toto, Haluk Cem Çakaloğlu, Kagan Karabulut, Vahit Mutlu, Bahar Busra Ozkan, Saban Celik, Anil Semiz, Selim Bodur, Enisburak Gül, Busra Murutoglu, Reyyan Yildirim, Bahadir Emre Baki, Ekin Arslan, Mehmet Ulusahin, Ali Guner, Nathan Walker, Nikhita Shrimanker, Simon Cole, Ryan Breslin, Ravi Srinivasan, Mohamed Elshaer, Kristina Hunter, Ahmed Al-Bahrani, Ignatius Liew, Nora Grace Mairs, Alistair Rocke, Lachlan Dick, Mobeen Qureshi, Debkumar Chowdhury, Naomi Wright, Clare Skerritt, Dorothy Kufeji, Adrienne Ho, Tharindra Dissanayake, Athula Tennakoon, Wadah Ali, Shujing Jane Lim, Charlene Tan, Stephen O'Neill, Catrin Jones, Stephen Knight, Dima Nassif, Abhishek Sharma, Oliver Warren, Rebecca White, Aia Mehdi, Nathan Post, Eliana Kalakouti, Enkhbat Dashnyam, Frederick Stourton, Ioannis Mykoniatis, Chelise Currow, Francisca Wong, Ashish Gupta, Veeranna Shatkar, Joshua Luck, Suraj Kadiwar, Alexander Smedley, Rebecca Wakefield, Philip Herrod, James Blackwell, Jonathan Lund, Fraser Cohen, Ashwath Bandi, Stefano Giuliani, Giles Bond-Smith, Theodore Pezas, Neda Farhangmehr, Tomas Urbonas, Miklos Perenyei, Philip Ireland, Natalie Blencowe, Kirk Bowling, David Bunting, Lydia Longstaff, Kenneth Keogh, Hyunjin Jeon, Muhammad Rafaih Iqbal, Shivun Khosla, Anna Jeffery, James Perera, Ahmad Aboelkassem Ibrahem, Tariq Alhammali, Yahya Salama, Shaun Oram, Thomas Kidd, Fraser Cullen, Christopher Owen, Michael Wilson, Seehui Chiu, Hannah Sarafilovic, Jennifer Ploski, Elizabeth Evans, Athar Abbas, Sylvia Kamya, Norzawani Ishak, Carly Bisset, Cedar Andress, Ye Ru Chin, Priya Patel, David Evans, Aidan Haslegrave, Adam Boggon, Kirsten Laurie, Katie Connor, Thomas Mann, Anahita Mansuri, Rachel Davies, Ewen Griffiths, Aized Raza Shahbaz, Calvin Eng, Farhat Din, Ariadne L'Heveder, Esther H.G. Park, Ramanish Ravishankar, Kirsten McIntosh, Jih Dar Yau, Luke Chan, Susan McGarvie, Lingshan Tang, Hui Lim, Suhhuey Yap, Jay Park, Zhan Herr Ng, Shahrukh Mirza, Yun Lin Ang, Luke Walls, Chloe Roy, Simon Paterson-Brown, Julian Camilleri-Brennan, Kenneth Mclean, Michelle S. D'Souza, Savva Pronin, David Ewart Henshall, Eunice Zuling Ter, Dina Fouad, Ashish Minocha, William English, Catrin Morgan, Dominic Townsend, Laura Maciejec, Shareef Mahdi, Onyinye Akpenyi, Elisabeth Hall, Hanaan Caydiid, Zakaria Rob, Tom Abbott, Hew D. Torrance, Robin Johnston, Mohammed Akil Gani, Gianpiero Gravante, Shivanchan Rajmohan, Kiran Majid, Shiva Dindyal, Christopher Smith, Madanmohan Palliyil, Sanjay Patel, Luke Nicholson, Neil Harvey, Katie Baillie, Sam Shillito, Suzanne Kershaw, Rebecca Bamford, Peter Orton, Elke Reunis, Robert Tyler, Wai Cheong Soon, Guled M. Jama, Dharminder Dhillon, Khyati Patel, Shayanthan Nanthakumaran, Rachel Heard, Kar Yan Chen, Behrad Barmayehvar, Uttaran Datta, Sivesh K. Kamarajah, Sharad Karandikar, Sobhana Iftekhar Tani, Eimear Monaghan, Philippa Donnelly, Michael Walker, Jehangirshaw Parakh, Sarah Blacker, Anil Kaul, Arjun Paramasivan, Sameh Farag, Ashrafun Nessa, Salwa Awadallah, Jieqi Lim, James Chean Khun Ng, Ravi P. Kiran, Alice Murray, Eric Etchill, Mohini Dasari, Juan Puyana, Nadeem Haddad, Martin Zielinski, Asad Choudhry, Celeste Caliman, Mieshia Beamon, Therese Duane, Mamta Swaroop, Jonathan Myers, Rebecca Deal, Erik Schadde, Mark Hemmila, Lena Napolitano, Kathleen To, Alex Makupe, Joseph Musowoya, Niels Van Der Naald, Dayson Kumwenda, Alex Reece-Smith, Kars Otten, Anna Verbeek, Marloes Prins, Alibeth Andres Baquero Suarez, Ruben Balmaceda, Chelsea Deane, Emilio Dijan, Mahmoud Elfiky, Laura Koskenvuo, Aurore Thollot, Bernard Limoges, Carmen Capito, Challine Alexandre, Henri Kotobi, Julien Leroux, Kalitha Pinnagoda, Nicolas Henric, Olivier Azzis, Olivier Rosello, Poddevin Francois, Sara Etienne, Philippe Buisson, Sophian Hmila, Joe-Nat Clegg-Lamptey, Osman Imoro, Owusu Emmanuel Abem, Dimitrios Papageorgiou, Vasiliki Soulou, Sabrina Asturias, Lenin Peña, Donal B. O’Connor, Alberto Realis Luc, Alfio Alessandro Russo, Andrea Ruzzenente, Antonio Taddei, Camilla Cona, Corrado Bottini, Giovanni Pascale, Giuseppe Rotunno, Leonardo Solaini, Marco Maria Pascale, Margherita Notarnicola, Mario Corbellino, Michele Sacco, Paolo Ubiali, Roberto Cautiero, Tommaso Bocchetti, Elena Muzio, Vania Guglielmo, Eugenio Morandi, Patrizio Mao, Emilia De Luca, Farah Mahmoud Ali, Justas Žilinskas, Kestutis Strupas, Paulius Kondrotas, Robertas Baltrunas, Juozas Kutkevicius, Povilas Ignatavicius, Choy Ling Tan, Jia Yng Siaw, Sir Young Yam, Ling Wilson, Mohamed Rezal Abdul Aziz, John Bondin, Carmina Diaz Zorrilla, Anass Majbar, Danjuma Sale, Lawal Abdullahi, Olabisi Osagie, Omolara Faboya, Adedeji Fatuga, Agboola Taiwo, Emeka Nwabuoku, Marte Bliksøen, Zain Ali Khan, Jazmin Coronel, Cesar Miranda, Idelso Vasquez, Luis M. Helguero-Santin, Jennifer Rickard, Adesina Adedeji, Saleh Alqahtani, Max Rath, Michael Van Niekerk, Modise Zacharia Koto, Roel Matos-Puig, Leif Israelsson, Tobias Schuetz, Mahmut Arif Yuksek, Meric Mericliler, Mehmet Uluşahin, Bernhard Wolf, Cameron Fairfield, Guo Liang Yong, Katharine Whitehurst, Natalie Redgrave, Caroluce K. Musyoka, James Olivier, Kathryn Lee, Michael Cox, Muhamed M.H. Farhan-Alanie, Rory Callan, Chali Chibuye, Tebian Hassanein Ahmed Ali, Syrine Rekhis, Muna Rommaneh, Zi Hao Sam, Thays Brunelli Pugliesi, Gabriel Pardo, and Ruth Blanco

Subjects
abdominal surgery, cost-effectiveness analysis, global surgery, high fraction of inspired oxygen, low-and middle-income countries, surgical site infection, Anesthesiology, RD78.3-87.3
Abstract

Background: This study assessed the potential cost-effectiveness of high (80–100%) vs low (21–35%) fraction of inspired oxygen (FiO2) at preventing surgical site infections (SSIs) after abdominal surgery in Nigeria, India, and South Africa. Methods: Decision-analytic models were constructed using best available evidence sourced from unbundled data of an ongoing pilot trial assessing the effectiveness of high FiO2, published literature, and a cost survey in Nigeria, India, and South Africa. Effectiveness was measured as percentage of SSIs at 30 days after surgery, a healthcare perspective was adopted, and costs were reported in US dollars ($). Results: High FiO2 may be cost-effective (cheaper and effective). In Nigeria, the average cost for high FiO2 was $216 compared with $222 for low FiO2 leading to a −$6 (95% confidence interval [CI]: −$13 to −$1) difference in costs. In India, the average cost for high FiO2 was $184 compared with $195 for low FiO2 leading to a −$11 (95% CI: −$15 to −$6) difference in costs. In South Africa, the average cost for high FiO2 was $1164 compared with $1257 for low FiO2 leading to a −$93 (95% CI: −$132 to −$65) difference in costs. The high FiO2 arm had few SSIs, 7.33% compared with 8.38% for low FiO2, leading to a −1.05 (95% CI: −1.14 to −0.90) percentage point reduction in SSIs. Conclusion: High FiO2 could be cost-effective at preventing SSIs in the three countries but further data from large clinical trials are required to confirm this.

Published
2023
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47. Accuracy of yellow fever case definition of epidemiologic surveillance, São Paulo, 2018

Author

Ana Freitas Ribeiro, Roberta Figueiredo Cavalin, Aparecida Mei Mingrone Klimas, Ricardo Manfredo, and Luciana Marques Sansão Borges

Subjects
Yellow Fever, Accuracy, Case Definition, Epidemiologic Surveillance, Public aspects of medicine, RA1-1270
Abstract

ABSTRACT OBJECTIVE To evaluate the accuracy of yellow fever (YF) suspected case definitions from the Brazilian Ministry of Health (BMH) and World Health Organization (WHO), as well as propose and evaluate new definitions of suspected cases, considering confirmed and discarded cases. METHODS The retrospective study was conducted at the Instituto de Infectologia Emílio Ribas (IIER), using the Epidemiologic Surveillance Form of YF cases. From the confirmed and discarded cases of YF, a logistic regression model was developed. The independent variables were used in a proposed definition of a suspected case of YF and its accuracy was evaluated. RESULTS In total, 113 YF suspect cases were reported, with 78 confirmed (69.0%). The definitions by BMH and WHO presented low sensitivity, 59% and 53.8%, and reduced accuracy, 53.1% and 47.8%, respectively. Predictive factors for YF were thrombocytopenia, leukopenia, and elevation of transaminases greater than twice normal. The definition including individual with acute onset of fever, followed by elevation of ALT or AST greater than twice the reference value AND leukopenia OR thrombocytopenia presented high sensitivity (88.3%), specificity (62.9%), and the best accuracy (80.4%), as proposed in the model. CONCLUSION The YF suspected case definitions of the BMH and the WHO have low sensitivity. The inclusion of nonspecific laboratory tests increases the accuracy of YF definition.

Published
2023
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48. Bariatric/Metabolic Surgery

Author

Castagneto-Gissey, Lidia, Casella-Mariolo, James, Mingrone, Geltrude, Barrett, James E., Editor-in-Chief, Flockerzi, Veit, Editorial Board Member, Frohman, Michael A., Editorial Board Member, Geppetti, Pierangelo, Editorial Board Member, Hofmann, Franz B., Editorial Board Member, Kuner, Rohini, Editorial Board Member, Michel, Martin C., Editorial Board Member, Page, Clive P., Editorial Board Member, Wang, KeWei, Editorial Board Member, Eckel, Juergen, editor, and Clément, Karine, editor

Published
2022
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50. The $^{7}$Be($\boldsymbol{n,p}$)$^{7}$Li reaction and the Cosmological Lithium Problem: measurement of the cross section in a wide energy range at n_TOF (CERN)

Author

Damone, L., Barbagallo, M., Mastromarco, M., Mengoni, A., Cosentino, L., Maugeri, E., Heinitz, S., Schumann, D., Dressler, R., Käppeler, F., Colonna, N., Finocchiaro, P., Andrzejewski, J., Perkowski, J., Gawlik, A., Aberle, O., Altstadt, S., Ayranov, M., Audouin, L., Bacak, M., Balibrea-Correa, J., Ballof, J., Bécares, V., Bečvář, F., Beinrucker, C., Bellia, G., Bernardes, A. P., Berthoumieux, E., Billowes, J., Borge, M. J. G., Bosnar, D., Brown, A., Brugger, M., Busso, M., Caamaño, M., Calviño, F., Calviani, M., Cano-Ott, D., Cardella, R., Casanovas, A., Castelluccio, D. M., Catherall, R., Cerutti, F., Chen, Y. H., Chiaveri, E., Cortés, G., Cortés-Giraldo, M. A., Cristallo, S., Diakaki, M., Dietz, M., Domingo-Pardo, C., Dorsival, A., Dupont, E., Duran, I., Fernandez-Dominguez, B., Ferrari, A., Ferreira, P., Furman, W., Ganesan, S., García-Rio, A., Gilardoni, S., Glodariu, T., Göbel, K., Gonçalves, I. F., González-Romero, E., Goodacre, T. D., Griesmayer, E., Guerrero, C., Gunsing, F., Harada, H., Heftrich, T., Heyse, J., Jenkins, D. G., Jericha, E., Johnston, K., Kadi, Y., Kalamara, A., Katabuchi, T., Kavrigin, P., Kimura, A., Kivel, N., Kohester, U., Kokkoris, M., Krtička, M., Kurtulgil, D., Leal-Cidoncha, E., Lederer-Woods, C., Leeb, H., Lerendegui-Marco, J., Meo, S. Lo, Lonsdale, S. J., Losito, R., Macina, D., Marganiec, J., Marsh, B., Martíne, T., Correia, J. G. Martins, Masi, A., Massimi, C., Mastinu, P., Matteucci, F., Mazzone, A., Mendoza, E., Milazzo, P. M., Mingrone, F., Mirea, M., Musumarra, A., Negret, A., Nolte, R., Oprea, A., Patronis, N., Pavlik, A., Piersanti, L., Piscopo, M., Plompen, A., Porras, I., Praena, J., Quesada, J. M., Radeck, D., Rajeev, K., Rauscher, T., Reifarth, R., Riego-Perez, A., Rothe, S., Rout, P., Rubbia, C., Ryan, J., Sabaté-Gilarte, M., Saxena, A., Schell, J., Schillebeeckx, P., Schmidt, S., Sedyshev, P., Seiffert, C., Smith, A. G., Sosnin, N. V., Stamatopoulos, A., Stora, T., Tagliente, G., Tain, J. L., Tarifeño-Saldivia, A., Tassan-Got, L., Tsinganis, A., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vlachoudis, V., Vlastou, R., Wallner, A., Warren, S., Weigand, M., Weiß, C., Wolf, C., Woods, P. J., Wright, T., and Žugec, P.

Subjects
Nuclear Experiment
Abstract

We report on the measurement of the $^{7}$Be($n, p$)$^{7}$Li cross section from thermal to approximately 325 keV neutron energy, performed in the high-flux experimental area (EAR2) of the n\_TOF facility at CERN. This reaction plays a key role in the lithium yield of the Big Bang Nucleosynthesis (BBN) for standard cosmology. The only two previous time-of-flight measurements performed on this reaction did not cover the energy window of interest for BBN, and showed a large discrepancy between each other. The measurement was performed with a Si-telescope, and a high-purity sample produced by implantation of a $^{7}$Be ion beam at the ISOLDE facility at CERN. While a significantly higher cross section is found at low-energy, relative to current evaluations, in the region of BBN interest the present results are consistent with the values inferred from the time-reversal $^{7}$Li($p, n$)$^{7}$Be reaction, thus yielding only a relatively minor improvement on the so-called Cosmological Lithium Problem (CLiP). The relevance of these results on the near-threshold neutron production in the p+$^{7}$Li reaction is also discussed.

Published
2018
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