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An enhanced adaptive neural network control scheme, based on the adaptive linear element (Adaline), is proposed and tested by applying it to a multimachine power system. Simulation results have shown that it is effective for different types of disturbances and over a wide range of operating conditions. Keywords: adaptive control, neural networks, power system stabilizer, Widrow-Hoff delta learning rule

Epilepsy is a chronic brain disorder which manifests as recurrent seizures. Electroencephalogram (EEG) signals are generally analyzed to study the characteristics of epileptic seizures. In this work, we propose a method for the automated classification of EEG signals into normal, interictal and ictal classes using Continuous Wavelet Transform (CWT), Higher Order Spectra (HOS) and textures. First the CWT plot was obtained for the EEG signals and then the HOS and texture features were extracted from these plots. Then the statistically significant features were fed to four classifiers namely Decision Tree (DT), K-Nearest Neighbor (KNN), Probabilistic Neural Network {PNN) and Support Vector Machine {SVM) to select the best classifier. We observed that the SVM classifier with Radial Basis Function (RBF) kernel function yielded the best results with aji average accuracy of 96%, average sensitivity of 96.9% and average specificity of 97% for 23.6 s duration of EEG data. Our proposed technique can be used as an automatic seizure monitoring software. It can also assist the doctors to cross check the efficacy of their prescribed drugs. [ABSTRACT FROM AUTHOR]

The human eye is one of the most sophisticated organs, with perfectly interrelated retina, pupil, iris cornea, lens, and optic nerve. Automatic retinal image analysis is emerging as an important screening tool for early detection of eye diseases. Uncontrolled diabetic retinopathy (DR) and glaucoma may lead to blindness. The identification of retinal anatomical regions is a prerequisite for the computer-aided diagnosis of several retinal diseases. The manual examination of optic disk (OD) is a standard procedure used for detecting different stages of DR and glaucoma. In this article, a novel automated, reliable, and efficient OD localization and segmentation method using digital fundus images is proposed. General-purpose edge detection algorithms often fail to segment the OD due to fuzzy boundaries, inconsistent image contrast, or missing edge features. This article proposes a novel and probably the first method using the Attanassov intuitionistic fuzzy histon (A-IFSH)–based segmentation to detect OD in retinal fundus images. OD pixel intensity and column-wise neighborhood operation are employed to locate and isolate the OD. The method has been evaluated on 100 images comprising 30 normal, 39 glaucomatous, and 31 DR images. Our proposed method has yielded precision of 0.93, recall of 0.91, F-score of 0.92, and mean segmentation accuracy of 93.4%. We have also compared the performance of our proposed method with the Otsu and gradient vector flow (GVF) snake methods. Overall, our result shows the superiority of proposed fuzzy segmentation technique over other two segmentation methods. [ABSTRACT FROM AUTHOR]

Electroencephalogram (EEG) signals are widely used to study the activity of the brain, such as to determine sleep stages. These EEG signals are nonlinear and non-stationary in nature. It is difficult to perform sleep staging by visual interpretation and linear techniques. Thus, we use a nonlinear technique, higher order spectra (HOS), to extract hidden information in the sleep EEG signal. In this study, unique bispectrum and bicoherence plots for various sleep stages were proposed. These can be used as visual aid for various diagnostics application. A number of HOS based features were extracted from these plots during the various sleep stages (Wakefulness, Rapid Eye Movement (REM), Stage 1-4 Non-REM) and they were found to be statistically significant with p-value lower than 0.001 using ANOVA test. These features were fed to a Gaussian mixture model (GMM) classifier for automatic identification. Our results indicate that the proposed system is able to identify sleep stages with an accuracy of 88.7%. [ABSTRACT FROM AUTHOR]

The analysis of electroencephalograms continues to be a problem due to our limited understanding of the signal origin. This limited understanding leads to ill-defined models, which in turn make it hard to design effective evaluation methods. Despite these shortcomings, electroencephalogram analysis is a valuable tool in the evaluation of neurological disorders and the evaluation of overall cerebral activity. We compared different model based power spectral density estimation methods and different classification methods. Specifically, we used the autoregressive moving average as well as from Yule-Walker and Burg's methods, to extract the power density spectrum from representative signal samples. Local maxima and minima were detected from these spectra. In this paper, the locations of these extrema are used as input to different classifiers. The three classifiers we used were: Gaussian mixture model, artificial neural network, and support vector machine. The classification results are documented with confusion matrices and compared with receiver operating characteristic curves. We found that Burg's method for spectrum estimation together with a support vector machine classifier yields the best classification results. This combination reaches a classification rate of 93.33%, the sensitivity is 98.33% and the specificy is 96.67%. [ABSTRACT FROM AUTHOR]

The eyes are complex sensory organs, they are designed to capture images under varying light conditions. Eye disorders, such as cataract, among the elderly are a major health problem. Cataract is a painless clouding of the eye lens which develops over a long period of time. During this time, the eyesight gradually worsens. It can eventually lead to blindness and, is common in older people. In fact, about a third of people over 65 have cataracts in one or both eyes. In this paper, we made use of two types of classifiers for identification of normal, cataract (early and developed stage), and post-cataract eyes using features extracted from optical images. These classifiers are artificial neural network and support vector machine. A database of 174 subjects, using the cross-validation strategy, is used to test the effectiveness of both classifiers. We demonstrate a sensitivity of more than 90% for both of these classifiers. Furthermore, they have a specificity of 100% and, as such, the results obtained are very promising. The proposed feature extraction and classification systems are ready clinically to run on a large amount of data sets. [ABSTRACT FROM AUTHOR]

Summary: The purpose of this study was to examine the pressure distribution under the feet in obese and non-obese subjects. The subjects were classified into four categories, each containing 20 study participants, as underweight, normal, overweight and obese subjects according to their body mass index (BMI) values. Footscans were obtained using the F-scan (Tekscan USA) in-shoe pressure measurement system. Various pedobarographic parameters such as the total plantar force, total contact area, peak pressures and power ratio (PR, the ratio of high-frequency power to the total power in an image) were evaluated. These parameters were subjected to analysis of variance (ANOVA) test with more than 95% confidence interval giving excellent P-values in all the categories. [Copyright &y& Elsevier]

Abstract: Oral cancer (OC) is the sixth most common cancer in the world. In India it is the most common malignant neoplasm. Histopathological images have widely been used in the differential diagnosis of normal, oral precancerous (oral sub-mucous fibrosis (OSF)) and cancer lesions. However, this technique is limited by subjective interpretations and less accurate diagnosis. The objective of this work is to improve the classification accuracy based on textural features in the development of a computer assisted screening of OSF. The approach introduced here is to grade the histopathological tissue sections into normal, OSF without Dysplasia (OSFWD) and OSF with Dysplasia (OSFD), which would help the oral onco-pathologists to screen the subjects rapidly. The biopsy sections are stained with H&E. The optical density of the pixels in the light microscopic images is recorded and represented as matrix quantized as integers from 0 to 255 for each fundamental color (Red, Green, Blue), resulting in a M × N ×3 matrix of integers. Depending on either normal or OSF condition, the image has various granular structures which are self similar patterns at different scales termed “texture”. We have extracted these textural changes using Higher Order Spectra (HOS), Local Binary Pattern (LBP), and Laws Texture Energy (LTE) from the histopathological images (normal, OSFWD and OSFD). These feature vectors were fed to five different classifiers: Decision Tree (DT), Sugeno Fuzzy, Gaussian Mixture Model (GMM), K-Nearest Neighbor (K-NN), Radial Basis Probabilistic Neural Network (RBPNN) to select the best classifier. Our results show that combination of texture and HOS features coupled with Fuzzy classifier resulted in 95.7% accuracy, sensitivity and specificity of 94.5% and 98.8% respectively. Finally, we have proposed a novel integrated index called Oral Malignancy Index (OMI) using the HOS, LBP, LTE features, to diagnose benign or malignant tissues using just one number. We hope that this OMI can help the clinicians in making a faster and more objective detection of benign/malignant oral lesions. [Copyright &y& Elsevier]

Abstract: The electrocardiogram (ECG) is a representative signal containing useful information about the condition of the heart. The shape and size of the P–QRS–T wave, the r–r interval, etc., may help to identify the nature of disease afflicting the heart. However, human observer cannot directly monitor these subtle details and it is difficult to evaluate the cardiac health using ECG alone. Hence, the fusion of ECG, blood pressure, saturated oxygen content and respiratory data for achieving improved clinical diagnosis of patients in cardiac care units. In this study, a computer based analysis and display of the heterogeneous signals for the detection of life threatening states is demonstrated using fuzzy logic based data fusion. And to evaluate the severity of the disease a new parameter, deterioration index is proposed and results are tabulated for various cases. [Copyright &y& Elsevier]

The American Cancer Society (ACS) recommends women aged 40 and above to have a mammogram every year and calls it a gold standard for breast cancer detection. Early detection of breast cancer can improve survival rates to a great extent. Inter-observer and intra-observer errors occur frequently in analysis of medical images, given the high variability between interpretations of different radiologists. Also, the sensitivity of mammographic screening varies with image quality and expertise of the radiologist. So, there is no golden standard for the screening process. To offset this variability and to standardize the diagnostic procedures, efforts are being made to develop automated techniques for diagnosis and grading of breast cancer images. A few papers have documented the general trend of computer-aided diagnosis of breast cancer, making a broad study of the several techniques involved. But, there is no definitive documentation focusing on the mathematical techniques used in breast cancer detection. This review aims at providing an overview about recent advances and developments in the field of Computer-Aided Diagnosis (CAD) of breast cancer using mammograms, specifically focusing on the mathematical aspects of the same, aiming to act as a mathematical primer for intermediates and experts in the field.

The electrocardiogram (ECG) is being commonly used as a diagnostic tool to distinguish different types of atrial tachyarrhythmias. The inherent complexity and mechanistic and clinical inter-relationships often brings about diagnostic difficulties to treating physicians and primary health care professionals creating frequent misdiagnoses and cross classifications using visual criteria. The current paper presents a methodology for ECG based pattern analysis for detection of atrial flutter, atrial fibrillation and normal sinus rhythm beats. ECG is an inherently non-linear and non-stationary signal; its variation may contain indicators of current disease, or warnings about impending cardiac diseases. Routinely used time domain and frequency domain methods will not be able to capture the hidden information present in the ECG beats. In the present study, we have used non-linear features of higher order spectra (HOS) to differentiate the normal, atrial fibrillation and atrial flutter ECG beats. The bispectrum features were subjected to independent component analysis (ICA) for data reduction. The ICA coefficients were subsequently subjected to K-nearest-neighbor (KNN), classification and regression tree (CART) and neural network (NN) classifiers to evaluate the best automated classifier. We have obtained an average accuracy of 97.65%, sensitivity and specificity of 98.75% and 99.53% respectively using ten-fold cross validation. Overall, the results show that application of higher order spectra statistics is useful for the classification of atrial tachyarrhythmias with reasonably high accuracies. Further validation of the proposed technique will yield acceptable results for clinical implementation.

In this paper, autoregressive modeling technique and neural network based modeling techniques are used to model and simulate electroencephalogram (EEG) signals. EEG signal modeling is used as a tool to identify pathophysiological EEG changes potentially useful in clinical diagnosis. The normal, background and epileptic EEG signals are modeled and the dynamical properties of the actual and modeled signals are compared. Chaotic invariants like correlation dimension (D(2)), largest Lyapunov exponent (lambda(1), Hurst exponent (H) and Kolmogorov entropy (K) are used to characterize the dynamical properties of the actual and modeled signals. Our study showed that the dynamical properties of the EEG signal modeled using neural network (NN) techniques are very similar to that of the signal.