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195 results on '"Milesi, G"'

5. Heat flow, thermal anomalies, tectonic regimes and high-temperature geothermal systems in fault zones

Author

Guillou-Frottier, Laurent, Milesi, Gaétan, Roche, Vincent, Duwiquet, Hugo, and Taillefer, Audrey

Subjects
Geothermal energy, Heat flow, Permeability, Fault zones, Fault geometry, Geophysics. Cosmic physics, QC801-809, Chemistry, QD1-999, Geology, QE1-996.5
Abstract

The potential of high-temperature $({>}150~\text{°}\mathrm{C})$ geothermal systems in crustal fault zones (fault cores and hundreds of meters wide networks of interconnected fractures in the damage zone) is underestimated. Based on numerical models, we show that topography-driven, poroelasticity-driven as well as buoyancy-driven forces play a significant role in the establishment of shallow (1–4 km) thermal anomalies in fault zones. We investigate the role of permeability, topography, fault dip, tectonic regime and fault geometry on the amplitude of thermal anomalies. Favorable conditions include: (i) a damage zone thickness $>$ 100 m, (ii) a minimum cumulative displacement of 100–150 m and (iii) fault zone lengths of at least one kilometer. Based on these parameters, we propose new potential targets for the geothermal exploration of fault zones in Western Europe.

Published
2023
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6. $\protect \mbox {}^{40}$Ar/$\protect \mbox {}^{39}$Ar geochronology of crustal deformation

Author

Monié, Patrick, Münch, Philippe, Milesi, Gaétan, Bonno, Michael, and Iemmolo, Arthur

Subjects
Geochronology, Argon, Fault, In situ dating, In vacuo encapsulation, Clays, Geophysics. Cosmic physics, QC801-809, Chemistry, QD1-999, Geology, QE1-996.5
Abstract

Crustal deformation is characterized by brittle and ductile faults that accommodate at different scales the strain imposed by plate tectonics. The aim of this contribution is to show with the help of different examples how the in situ $\mbox {}^{40}$Ar/$\mbox {}^{39}$Ar dating of synkinematic neocrystallized minerals in ductile shear zones and the step-heating $\mbox {}^{40}$Ar/$\mbox {}^{39}$Ar dating of synkinematic authigenic clays in fault gouges can bring information on the timing of fault activity. However, due to their complex evolution, interpretation of the argon signature in fault zones requires consideration of several effects among which re- or neocrystallization, inheritance and fluid interaction processes are dominant.

Published
2023
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7. MUTATIONAL SPECTRUM OF BRAF, NRAS AND KRAS IN MULTIPLE MYELOMA

Author

Lionetti M, Barbieri M, Todoerti K, Agnelli L, Marzorati S, Fabris S, Ciceri G, Galletti S, Milesi G, Manzoni M, Mazzoni M, Greco A, Tonon G, Musto P, Baldini L, Neri A, Lionetti, M, Barbieri, M, Todoerti, K, Agnelli, L, Marzorati, S, Fabris, S, Ciceri, G, Galletti, S, Milesi, G, Manzoni, M, Mazzoni, M, Greco, A, Tonon, G, Musto, P, Baldini, L, and Neri, A

Published
2015

9. Shock cardiogeno al’esordio di sclerosi multipla in maschio di 13 anni

Author

MOLINARO, ANNA, Zonno G, Milesi G, Cordioli C, Micheli R, Fazzi E., SINPIA Società Italiana di Neuropsichiatria dell'Infanzia e dell'Adolescenza, Molinaro, Anna, Zonno, G, Milesi, G, Cordioli, C, Micheli, R, and Fazzi, E.

Subjects
età pediatrica, insufficienza cardiaca acuta, sclerosi multipla
Published
2011

12. High-resolutionMR (7 Tesla) microscopy of the human hippocampus

Author

Coras, R, Garbelli, R, Milesi, G, Frassoni, C, Zucca, I, Mastropietro, A, Mühlebner, A, Hess, A, Aronica, E, Blümcke, I, and Spreafico, R

Subjects
ddc: 610, 610 Medical sciences, Medicine, nervous system diseases
Abstract

Questions: The human hippocampal formation is morphologically affected in many neurological disorders such as Alzheimer's disease or mesial temporal lobe epilepsy (mTLE). Its internal structure remains, however, difficult to recognize at 1.5T or 3T magnetic resonance imaging (MRI). We aimed to [for full text, please go to the a.m. URL], 57th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)

Published
2012
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13. Gli n-3 PUFA oggi

Author

Nodari, Savina, Manerba, Alessandra, Triggiani, M, Milesi, G, Lupi, L, Rocco, E, Villa, C, Berlinghieri, N, Mianadi, C, Ciccarese, C, Armato, A, and DEI CAS, Livio

Published
2012

17. Влияние n-3 полиненасыщенных жирных кислот на функцию левого желудочка и функциональную способность у больных дилатационной кардиомиопатией

Author

Nodari, S., Triggiani, M., Campia, U., Manerba, A., Milesi, G., Cesana, B., Gheorghiade, M., and Dei, Cas

Subjects
КАРДИОМИОПАТИЯ,ФУНКЦИОНАЛЬНЫЙ РЕЗЕРВ,СЕРДЕЧНАЯ НЕДОСТАТОЧНОСТЬ,НЕИШЕМИЧЕСКАЯ ДИЛАТАЦИОННАЯ КАРДИОМИОПАТИЯ,N-3 ПОЛИНЕНАСЫЩЕННЫЕ ЖИРНЫЕ КИСЛОТЫ,ФУНКЦИОНАЛЬНЫЙ КЛАСС СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ
Abstract

Цель. Оценить влияния n-3 полиненасыщенных жирных кислот (ПНЖК) на систолическую функцию левого желудочка (ЛЖ) у больных хронической сердечной недостаточностью (СН), обусловленной неишемической дилатационной кардиомиопатией (ДКМП). Материал и методы. В проспективное исследование были включены 133 больных хронической СН, обусловленной неишемической ДКМП с минимально выраженными симптомами на фоне стандартной терапии. Больные были рандомизированы в группы лечения плацебо или n-3 ПНЖК в дозе 2 г/сут. До начала лечения и через 12 мес после рандомизации у больных была проведена оценка функции ЛЖ и функционального резерва по данным эхокардиографии и кардиопульмонального нагрузочного теста, а также определяли функциональный класс NYHA (New York Heart Association). Результаты. Через 12 мес после рандомизации в группы лечения были выявлены значимые различия (р

Published
2011

27. Temporal lobe epilepsy: a combined study with high field (7T) Magnetic Resonance Imaging and optical and ultrastructural histopathology

Author

GARBELLI, RITA, Milesi, G, MILESI, GLORIA, GARBELLI, RITA, Milesi, G, and MILESI, GLORIA

Abstract

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy with 60-75% of cases reported in surgical series. The hippocampus is involved in the genesis of the seizures and hippocampal sclerosis (HS) is the most frequent neuropathological finding observed in surgical samples. However extra-hippocampal neocortical structures may also be involved and the focal cortical dysplasia (FCD) is the most common second alteration frequently associated with HS. Aim of this project was to clarify, both at radiological and neuropathological level, the abnormalities frequently observed in the temporal pole of many TLE patients as the focal cortical dysplasia, the hippocampal sclerosis and the radiological alteration of grey/white matter boundary called “blurring”. The study was performed on surgical specimens of human temporal cortices and hippocampi from TLE patients and autoptic hippocampi at different stage of development submitted first to high resolution (7T) MRI and then processed for histological analysis. Comparison between 7T MRI data with corresponding histological and immunohistochemical features was done. The first part of this study demonstrates that thanks to differences in MRI signal intensities, depending on different density and distribution of cells and myelin fibres, high-resolution ex-vivo MRI enables to visualize the intracortical organization in normal and pathological areas and can detect the subtle architectural alterations in samples presenting dysplastic cortex. The temporo-polar blurring has demonstrated to be due to a great degeneration of fibre bundles in the white matter and, since the age at epilepsy onset is earlier in patients with blurring in comparison to those without blurring, these data suggest that it consists in a slowly evolving chronic degeneration process with the redistribution of the remaining fibres. The comparative imaging-histology investigation on healthy hippocampal specimens shows that 7T MRI can identify the main anato

Published
2014

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