11 results on '"Milani MS"'
Search Results
2. Lichenified plaque in chin after chronic irritation
- Author
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Doniya Milani, MS, Alejandro Rabionet, MD, Paul Rodriguez-Waitkus, MD, PhD, Ann Lin, DO, and Wei-Shen Chen, MD, PhD
- Subjects
follicular keratosis of the chin ,maskne ,traumatic anserine folliculosis ,Dermatology ,RL1-803 - Published
- 2023
- Full Text
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3. Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery
- Author
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Chapman, Sj, Clerc, D, Blanco‐colino, R, Otto, A, Nepogodiev, D, Pagano, G, Schaeff, V, Soares, A, Zaffaroni, G, Žebrák, R, Hodson, J, Glasbey, Jc, Pata, P, Pellino, G, Sgrò, A, Elst, T, Van Straten, S, Knowles, Ch, Borakati, A, Bath, Mf, Yasin, Ih, Mclean, K, Arthur, T, Kovacevic, M, Delibegovic, S, Karamanliev, M, Swamad, M, Paramasivam, R, Martensen, A, Larsen, Hm, Rädeker, L, Frey, Pe, Kechagias, A, Venara, A, Duchalais, E, Ioannidis, A, Pata, F, Pasquali, S, Simioni, A, Farina, V, Podda, M, Lorenzon, L, Jakubauskas, M, Elst, Tr, Chu, M, Fagan, Pvb, Wells, Ci, Alagoa João, A, Juloski, J, Ciubotaru, C, Popescu, S, Yanishev, A, Lee, S, Ozkan, Bb, Yagız Sen, A, Aktas, Mk, Baki, Be, Yüksek, B, Kamarajah, S, Khaw, Ra, Mills, E, Goodson, R, Thakral, N, Ablett, Ad, Adra, M, Kwek, I, Khan, Sm, Quinn, P, Manley, Lr, Badran, A, Ramjeeawon, A, Campbell, A, Tan, Hl, Rye, Ds, Rajaraman, N, Norman, Jg, Vutipongsatorn, K, Solomou, G, Akhbari, M, Ali, A, Murray, V, Baker, Dm, Brandao, Bd, Stainer, B, Thavayogan, R, Jones, D, Onafowokan, Oo, Gharooni, A, Dabab, N, Carlton‐carew, S, Kungwengwe, G, Gabriel, M, Sewart, E, Shortland, Tc, Lawday, S, Pockney, P, Dawson, A, Brumfitt, Cd, Stewart, P, Ng, B, Luong, Jk, Ivanov, V, Borisova, A, Neykov, V, Kunčarová, K, Kološová, B, Antonova, T, Farkašová, M, Harbjerg, Jl, Brandsborg, S, Brinck, S, Kjaer, Md, Mark‐christensen, A, Unbehaun, Kp, Dalsgaard, P, Lycke, Kd, Lenaoures, P, Brigand, C, Dumange, E, Gout, M, Moehwald, C, Prem, M, Alhalabi, O, Sliwinski, S, Krupp, J, Gablenz, E, Schmitzer, L, Kopp, A, Steinle, J, Gsenger, J, Pohl, Lj, Riccardi, M, Christodoulou, Im, Konstantinidis, M, Machairas, N, Zoikas, A, Balalis, D, Manatakis, Dk, Aguilera, Ml, Marano, L, Fleres, F, Lovisetto, F, Sasia, D, Segalini, E, Pata, G, Lucchi, A, Sagnotta, A, Campagnaro, T, Petrelli, F, Gallo, G, Papandrea, M, Testa, V, Sinibaldi, G, Di Candido, F, Colombo, F, Perrone, G, Aresu, S, Biancafarina, A, Canonico, G, Pagnanelli, M, Curletti, G, Bini, R, Manzoni Garberini, A, Impellizzeri, H, Cillara, N, Tutino, R, Picciariello, A, Coletta, D, Savino, G, Ferrara, F, Tamini, N, Talamo, G, Parini, D, Giamundo, P, lo Conte, A, Ripetti, V, Pesce, A, Menduni, N, Giudicissi, R, Goldin, E, Rega, D, Belli, A, Andriola, V, Gordini, L, Foppa, C, Piccolo, G, Birindelli, A, Ferrari, C, Ballarini, Z, Tirelli, F, Milone, M, De Rosa, M, Pipitone Federico, Ns, Molteni, B, Tilocca, Pl, Sancini, G, Piozzi, Gn, Lauretta, A, Poillucci, G, Mulas, S, Simcikas, D, Portelli, L, Wijnbergen, Jwm, Dinger, Tl, Doesschate, Sfh, Dalen, Ashm, Bos, Dd, Hansmann, M, Medina Feliz, J, Kuiper, Sz, Abdulrahman, Z, Pruijssers, Sr, Farik, S, Elliott, Bm, Geneta, Vp, Wilton, S, Kandelaki, H, Peng, Sl, Campbell, S, Lim, Yk, Yassaie, Ss, Murray, M, Haran, C, Tan, J, Castro, J, Laranjeira, A, Catarino, S, Neves‐marques, C, Correia, Jg, Vieira, Bn, Quintela, Ac, Serra, Ml, Maciel, J, Cunha, M, Aparício, Dj, Neves, J, Azevedo, J, Romano, M, Eiró, F, Romano, J, Monteiro, C, Claro, M, Almeida, Mr, Peyroteo, M, Machado, Nd, Capote, H, Ferreira, M, Sousa, X, Devesa, H, Cavadas, D, Guerreiro, I, Costa, M, Salman, M, English, C, Mohammed, N, Litvin, A, Ćuk, Vv, Mészárosová, K, Jaich, R, De Lima, H, Brooks, S, Marx, M, Nshalati Salvation, M, Blaser, B, Piazza, G, Gagliardi, B, Serin, H, Yurdaor, Ss, Arslan, E, Kopac, O, Uyanik, A, Ozmen, Bb, Tiftik, E, Aksoy, B, Yalcinkaya, A, Ozoglu, F, Kocer, Md, Bilicen, G, Cinar, En, Uslu, Ö, Kaya, Y, Wong, J, Farhan‐alanie, Mmh, Suresh, G, Asif, A, Finch, Bj, Bhahirathan, Y, Herron, J, Yi Tew, Z, Obukofe, R, Russell, C, Suchett‐kay, I, Netke, T, Williams, L, Kisiel, A, Liu, Fy, Claireaux, H, James, P, Mondal, A, Kalderon, R, Nadama, Hh, Al‐saraff, Z, Tam, Jph, Powell‐chandler, A, Wood, F, Gorgievska, Rebecca, Ragavoodoo, A, Thakrar, C, Rojoa, D, Palmer, C, Davidson, K, Giacci, L, Hale, J, Gan, Fw, Makin‐taylor, R, Hey, Cy, Toh, C, Findlay, Jm, Griffiths, N, Ganesananthan, S, Jasionowska, S, Poustie, M, Wong, C, Turner, T, Pyc, W, Sloper, W, Warner, C, Coey, J, Mason, D, Sait, S, Kowal, M, Owen, M, Saiyed, A, Ashworth, I, Akbari, K, Curran, M, Martin, P, Parker, D, Kwok, K, Lye, C, Ghaly, M, Sammour, T, Lewis, D, Mundasad, R, Wilkes, A, Ctercteko, G, Maslyankov, S, Dimov, R, Iliev, S, Dimitrov, D, Marek, F, Örhalmi, J, Skalický, P, Skalický, T, Chrz, K, Christensen, P, Worsøe, J, Kristensen, Es, Emmertsen, Kj, Loeve, Us, Mihaljevic, Al, Herrle, F, Konstantinidis, Km, Korkolis, D, Karanikas, I, Vincenti, L, Anania, G, Borghi, F, Agresta, F, Maretto, I, Parisi, A, Bucci, L, De Palma, G, Guglielmi, A, Cucinotta, E, La Torre, F, Cianchi, F, Guerrieri, M, Trompetto, M, Persiani, R, Micheletto, G, Cantafio, S, Ronconi, M, Bisagni, Pag, De Prizio, M, Franceschi, A, Galleano, R, Cavallini, M, Brescia, A, D'Ambra, L, Benevento, A, Niolu, P, Calgaro, M, Colangelo, E, Grottola, T, Altomare, Df, Puleo, S, Salamone, G, Pietrabissa, A, Poggioli, G, Erdas, E, Ottonello, R, Tonini, V, Selvaggi, F, Sammarco, G, Ceccarelli, G., De Nisco, C, Surgo, D, Taglietti, L., Ozolins, A, Sivinš, A, Poskus, T, Psaila, J, Bemelman, Wa, Graat, Lj, Langenhoff, B, Wijnhoven, Bpl, Ven, Ahw, Poelman, M, Stassen, Lps, Slooter, G, Acherman, Yiz, Hoff, C, Gerhards, Mf, Stommel, Mwj, Hazebroek, Ej, Geloven, Aaw, Schasfoort, Ra, Leeuwen, Bl, Tuynman, Jb, Tilburg, Mwa, Boerma, Eg, Sharma, P, Jenkins, B, Bissett, Ip, Herd, A, Gordon, A, Vernon, D, Omundsen, M, Ly, J, Reddy, A, Bonnet, G, Harmston, C, Morales, M, Francisco, V, Costa, S, Manso, A, Amorim, E, Pereira, J, Cardoso, J, Ourô, S, Caratão, M, Nascimento, C, Ribeiro da Silva, B, Taranu, V, Dias, R, Mendes, J, Allen, M, Silva, A, Carlos, S, Barbosa, E, Carneiro, C, Ramos, L, Lencastre, L, Martins, R, Silva‐vaz, P, Ridgway, Pf, Mcnamara, Da, Cahill, R, Hogan, A, Larkin, J, O'Connell, Pr, Negoi, I, Abelevich, A, Ćuk, Vm, Vician, M, Ede, C, Sardiwalla, I, Mulira, S, Montwedi, D, Oyomno, M, Hübner, M, Petermann, D, Sauvain, Mo, Ozben, V, Geçim, Ie, Disçi, E, Rencuzogullari, A, Kurt, A, Bisgin, T, Pehlivan, M, Isik, A, Onur, E, Leventoglu, S, Haksal, Mc, Erturk, Ms, Keskin, M, Guner, A, Tutcu Sahin, S, Ozbalci, Gs, Pergel, A, Albayrak, D, Bruce, D, Fearnhead, N, Arthur, J, Harron, M, Beattie, G, Titu, L, Saunders, M, Phillips, J, Dindyal, S, Cresswell, B, Gercek, Y, Lee, J, Linn, T, Faulkner, G, Lockwood, S, Rees, J, Charalabopoulos, A, Campbell, B, Kontovounisios, C, Amarnath, T, Johnson, M, Epanomeritakis, E, Vigs, S, Nastro, P, Gilliam, A, Smolarek, S, Wilson, T, Orbell, J, Mcintyre, R, Agarwal, T, Hainsworth, P, Patel, P, Vijay, J, Liu, B, Dhruva Rao, P, Roxburgh, C, Vipond, M, Youssef, H, Thorn, C, Schizas, A, Denley, S, Bowley, D, Das, K, Cuming, T, Saha, A, Chung, L, Pitt, J, Davis, P, Jones, O, Taylor, M, Bhargava, A, Haji, A, Watson, N, Bloom, I, Singh, B, Norwood, M, Gurjar, S, Stylianides, N, Mirza, S, Evans, M, Williams, G, Patil, P, Hernon, J, Finch, G, Green, S, Chapple, K, Fafemi, O, Warusavitarne, J, Samee, A, Carden, C, Ong, L, Verma, K, Joseph, A, Rawat, N, Pinkney, T, Oke, O, Glen, P, Maxwell‐armstrong, C, Oliphant, R, Garner, J, Moug, Sj, Middleton, S, Lund, Jn, Smart, Nj, Osborn, G, Moore, T, Raymond, T, Hany, Ts, Clarke, R, Khera, G, Brady, R, Sellahewa, C, Mason, C, Torrance, A, Lasithiotakis, K, Knight, J, Pullybank, A, Ainsworth, P, Reid, F, Ramwell, A, Maslekar, S, George, R, Skull, A, Holtham, S, Muhammad, K, Lal, R, Varcada, M, Smith, Fm, Howlader, M, Defriend, D, Kirk, S, Richards, T, Evans, C, Borg, C, Telford, K, Sarfraz, N, Busby, K, Hollingshead, J, Speake, D, Pawa, N, West, D, Chadwick, M, Komolafe, O, Richardson, S, Thornton, M, Goede, A, Osborne, C, Bandyopadhyay, D, Foong, J, Lee, Yj, Liebenberg, P, Mijalkov, D, Wells, A, Bull, N, Ajmera, A, Warburton, T, Morgan, S, Mahmoud, A, Schachtel, M, Mikhail, B, Fomin, I, Mekaeil, B, Taylor, N, Stevenson, C, Drane, A, Pahalawatta, U, Lai, Lt, Debiasio, A, Jun, Hjs, Hengpoonthana, R, Mendis, Dm, Robb, Pm, Lee, Hj, Wyche, Aab, Davis, Lt, Chrimes, A, Agarwal, A, Zhao, J, Williams, S, Jayalath, Jmsn, Khor, S, Muddasani, T, Childs, S, Ridgway, S, Blefari, Nda, Tam, H, Puchalski, N, Ngai, C, Mackenzie, J, Johnson, N, Holmes, M, Zuzek, R, Saluja, T, Gould, T, Goh, Yk, Selvaraj, T, Beh, Yz, Dudi‐venkata, Nn, Horne, D, Borrow, Jl, Campbell, C, Cousins, G, Jackson, L, Maheepala, K, Zhao, S, Holden, E, Tutt, L, Thompson, B, Collins, H, Louie, F, Buckland, B, Smith, D, Chong, C, Chua, Th, Nayak, C, Redmond, J, Tan, Rr, Gramlick, M, Teh, Js, Sy, Ng, Britten‐jones, P, Mohd Rosli, R, Pham, Hdv, Jegathees, T, Coulter‐nile, Smcj, Gosselink, Mp, Wang, Yl, Maciaszek, M, Chrapko, Ps, Nair, A, Thirugnanasundralingam, V, Muir, K, Salibasic, M, Pavlov, V, Paycheva, T, Lyulenina, E, Kolev, N, Nguen, D, Mitkov, Y, Mitkov, E, Vladova, P, Dimitrov, V, Hussain, M, Gabarski, A, Ivanov, T, Yotsov, T, Ilieva, I, Akisheva, A, Shoshkova, M, Nawaz, E, Feradova, H, Mladenov, T, Jozaf, V, Klail, T, Pös, M, Adel, A, Sotona, O, Bartoš, M, Amjad, T, Malý, O, Berec, S, Hanušová, M, Hurný, M, Riško, J, Ludvik, M, Stercz, M, Treskoň, R, Pospíšil, M, Hlaváčová, L, Tomanová, D, Chodora, S, Houdek, O, Novický, R, Sobotková, K, Cha, S, šuta Kimle, K, Jirankova, K, Bujda, M, Paclík, A, Trap, A, Jürgens‐lahnstein, J, Storm, M, Damgaard, I, Olawi, F, Ehlem, F, Raos, M, Kristensen, Fp, Bønnerup, K, Amiri, S, Enevoldsen, M, Højgaard Pedersen, J, Jepsen, Bn, Hillgaard, Tk, Erichsen, Sb, Nielsen, Cv, Madsen, Cp, Bjerke, J, Skejø, Cd, Aabling, Rr, Sørensen, Js, Turunen, A, Katunin, J, Niskakangas, M, Vignaud, T, Frey, S, Ricolleau, C, Chanut, F, Magnin, J, Seiboldt, T, Beck, L, Zamzow, K, Betge, F, Poncelet, A, Truant, M, Hauschild, H, Neugebauer, N, Schöning, L, Simon, S CS, Galata, C, Karampinis, I, Thäwel, T, Seckler, Am, Kerem, C, Durdevic, S, Antonakopoulos, F, Mathioulaki, A, Chrysoheris, P, Athanasopoulos, Pg, Kalles, V, Spyrou, I, Barkolias, C, Paspala, A, Papaconstantinou, D, Spartalis, E, Arkadopoulos, N, Prodromidou, A, Garoufalia, Z, Mendez, D, Rosales, J, Flores, M, Garcia, M, Garcia, A, Noriega, Z, Torselli, D, Rodriguez, J, Lafranceschina, S, Artioli, E, Giaccari, S, Nevoso, V, Schimera, A, Marino, S, Geretto, P, Pellegrino, L, Borghi, B, Marano, A, Corino, C, Cannata, G, Giuffrida, Mc, Landra, F, Ongaro, D, Baronio, G, Raimondo, S, Casiraghi, S, Salvadori, R, Finotti, E, Ciccioli, E, Galgano, A, Zuin, M, Bettella, A, Barina, A, Vendramin, E, Palano, G, Schiavone, D, Di Cintio, A, Gemini, A, Trastulli, S, De Luca, M, Desiderio, J, Gubbiotti, F, Cigognini, M, Maffioli, A, Colombo, S, Bondurri, A, Sampietro, G, Foschi, D, Manigrasso, M, Danzi, M, Amato, R, Anastasio, L, Mastella, F, Basile, R, Peltrini, R, Marra, E, Luglio, G, Giglio, M, Anoldo, P, Vertaldi, S, Grimaldi, L, Tammaro, N, Pedrazzani, C, Turri, G, Lazzarini, E, Conti, C, Vulcano, I, Bertilone, E, Pintabona, G, Viscosi, F, Cerasari, S, Galiffa, G, Lapolla, P, Del Basso, C, Cirillo, B, De Toma, G, Fazzi, K, Bini, S, Coratti, F, Montanelli, P, Grandi, S, Nelli, T, Ben Khaled, N, Cammelli, F, Ferrini, E, Billo, Me, Marrosu, Ag, Scognamillo, F, Pala, C, Attene, F, Carboni, L, Ruggiu, Mw, Gabbas, G, Marziali, I, Mazzocato, S, Vergari, R, Piazzai, F, Kubolli, I, Aggiusti, A, Paolucci, A, Ortenzi, M, Olivieri, M, Belluco, C, Antona, Ad, Basso, S, Morino, M, Mistrangelo, M, Clerico, G, De Santi, G, Bitonti, Mf, Frattalone, M, Fico, V, Santullo, F, Belia, F, Spinelli, A, Marco, M, Bevilacqua, M, Tringali, D, Bevilacqua, E, Panizzo, V, La Manna, V, Migliore, G, Aversano, A, Fares Bucci, A, Marino, F, Carbone, F, Incollingo, P, Romano, Fm, Zalla, T, Baraghini, M, Romoli, L, Calussi, M, Vellei, S, Genzano, C, Feroci, F, Vita, M, Barberis, A, Serra, D, Grassia, M, Romelli, M, Ruggiero, S, Percassi, A, Magri Piccinini, A, Monti, M, Magnoli, M, Romano, S, Gaetano, P, Pilotta, F, Baldassarre, L, Bonati, E, Saba, A, Moretto, G, Bacchion, M, Casaril, A, Inama, M, Creciun, M, Stella, M, Gobatti, D, Angelini, M, Andolfi, E, Miranda, E, Scricciolo, M, Provenza, G, Cavallina, G, Frezza, B, Fontani, A, Malatesti, R, Pellicanò, Ga, Anania, M, Pulighe, F, Cruccu, A, Murru, Ml, Massaiu, C, Balestra, F, Pazzona, M, Giannella, A, Santangelo, M, Frangella, F, Magagnano, D, Liberatore, P, Brenna, R, Giani, A, Tirotta, F, Famularo, S, Angrisani, M, Ceresoli, M, Rondelli, F, Ceccarelli, G, Angelucci, Gp, Scaramuzzo, R, Larcinese, A, Fioriti, C, Picone, E, Nardi, M, Castagnoli, G, Bartoli, A, Bellochi, R, Spaziani, A, Conti, D, Poponesi, V, Trippetti, M, Amicucci, S, Tazza, G, Procacci, P, Giovannini, F, Basile, E, Caristo, G, De Nardi, P, Rosati, R, Marcocci, G, Vignali, A, Malerba, M, Percivale, A, Ghazouani, O, Reggiani, L, Spirito, C, Moschetta, G, Cosmi, F, Romeo, G, Gasparrini, M, Sucameli, F, Gennai, A, Moggia, E, Bianchi, C, Bonfante, P, Macina, S, Feleppa, C, Imperatore, M, Tenconi, Sm, Rausei, S, Maioli, D, Marchionini, V, Sparta, C, Mura, Fa, Barmina, M, Lorettu, A, Rettaroli, C, Mastino, G, Ruggiu, Gv, Mura, Ga, Perrone, Ba, De Angelis, M, Mereu, A, Adamo, V, Bianco, C, Ricciardiello, M, Campanaro, C, Panaccio, P, Esposito, Lm, D'Ascanio, F, Pietroletti, R, Chetta, N, Aquilino, F, Di Marco, F, Amico, A, Schembari, E, Puglisi, S, Licari, L, Campanella, S, Profita, G, Falco, N, Rotolo, G, Venturelli, P, De Marco, P, Marcianò, M, Argenti, F, Milani, Ms, Malabarba, S, Giambartolomei, G, Vella, I, Gronchi, F, Ruggieri, A, Roggiani, A, Balsamo, F, Gori, A, Cuicchi, D, D'Alessio, R, Benvenuto, D, Podda, F, Cappellacci, F, Salaris, C, Sanna, S, Marcialis, J, Mosino, L, Peddis, M, Melis, S, De Donno, G, Aru, Ac, Falsetti, E, Lanari, J, D'Errico, U, Bianchini, S, Figà, F, Caiazzo, A, Selvaggi, L, Capozzolo, A, Cerra, C, Pirillo, M, Cravano, S, Libri, I, Laquatra, N, Isabello, A, Truškovs, A, Bartnick, A, Malcevs, E, Machatschek, Mj, Alm, J, Lapsa, S, Delorme, M, Zeynalov, F, Larnovskis, J, Sauka, J, Bodrov, D, Gailumsis, R, Wiemann, Am, Müller, Nl, Jelovskis, I, Deksnis, D, Bauermeister Potts, O, Slimbajevs, T, Samalavicius, Ne, Nutautiene, V, Zeromskas, P, Jurgaitis, J, Aliosin, O, Slepavicius, A, Eismontas, V, Kybransiene, M, Dulskas, A, Kuliavas, J, Kavaliauskas, P, Kavaliauskaite, R, Poškus, E, Danys, D, Kryžauskas, M, Mikalauskas, S, Rackauskas, R, Drungilas, M, Poškus, T, Jotautas, V, Strupas, K, Cachia, C, Cefai, C, Youssef, Y, Degaetano, D, Debono, S, Sammut, M, Cassar, J, Sammut, K, Looyen, R, Becker, Maj, Comert, D, Molder, L, Tromp, J, Matthee, E, Tissen, Ym, Brinkhuis, E, Vries, Hs, 't Hart, E, Beckers, K, Bekker, Y, Kakar, S, Smaalen, Tc, Veen, Oc, Dingemans, Sa, Brink, Lc, Vijgen, Ghej, Voort, Emf, Pool, A, Rest, Klc, Haak, T, Sluijpers, Nrf, Molenaar, Cjl, Gordinou de Gouberville, Mc, Saleh, S, Mens, Ma, Hoeks, Em, Nieuwenhuizen, S, Praag, Em, Westerduin, E, Smit, Mpcm, Lely, Sj, Nasimi, B, Gerdsen, M, Stijns, Rch, Leow, Tys, Penningnieuwland, G, Ruiter, A, Ribbers, T, Aarts, Cam, Tulek, Ms, Jonge, J, Kocak, S, Alqethami, Hj, Constansia, R, Elst, Pc, Tissink, Mw, Grüter, A, Vroom, Y, Voeten, Dm, 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Staden N., McDuling C.R., Claassen L., Kruger C., Weyers J., Lecler J., Mignon G., Vanoni A., Henkens A., Jarrar G., Odovic M., Willemin M., Milliet O., Hahnloser D., Demartines N., Teixeira H., Pittet O., Haller M.L., Huot A., Kefleyesus A., Bugmann A., Piotet L.M., Meijers L., Kurtoglu G.K., Sel E.K., Isler V.C., Yilmaz B.S., Adiyaman C., Kara M., Demirkaya H.C., Korkmaz H.K., Pektas A.M., Guner B., Islek E.C., Tombul H.B., Boztug C.Y., Tinaz A., Yilmaz M., Karaman Y., Akin F.A., Dansuk S., Bascavus M., Kaya M., Kutlu B., Seker M.C., Erten V., Memis U., Kocak Z.B., Karapinar Y.E., Fakirullahoglu M., Koseoglu E., Yeni M., Aykun N., Agca M.H., Bilen C., Kilinc I., Atar C., Kilic V., Aktuna C., Aba M., Alim Y.E., Binbuga M., Kurklu O., Ceylan C., Yilmaz S., Calar S.N., Yildirim N., Yavuz G., Can B., Cesmeli E., Kus D., Kavar R.C., Cevlik A.D., Cengiz U., Turk E.G., Yilmaz I., Erdonmez H., Gursoy F., Kara H., Onsal U., Ozbek M., Kasar P.A., Ipor A., Ozen D., Olmez M., Altintas E., Toklu 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S., Alshakhs A., Ahmeidat A., Goergen N., Ali Z., Mullarkey L., Walshe R., Lewis E., Berry B., Moneim J., Mookerjee S., Christy S., Ojofeitimi O., Carroll L., Hylands A., Delaugere L.P., Reveendran D., Coulter C., Ralston C., Laverty L., Gallagher P., Ahmed A., Yeo Y.Q., Elliott D., Bennett J., Mcnamara M., Sivarajah S., Dunmore C., Aitken G., Nair M., Aly M.H., Buari M., Ahmed K., Sheikh Z., Monks M., Lehmann J., Rotimi O., Bell T., Limnatitou D., Gormley S., Taleongpong P., Patel V., Macgregor L., Amini S., Turner C., Dwyer-Hemmings L., Busuttil A., Powell J., Hensher C., Vivian F., Wcislo K., Millar Z., Hirosue S., Ogunmwonyi I., Nakakande D., Gaze H., Nirmalanantha A., Bin Amran A.M., Foulkes A., Jones N., Pillai S., Khoury G., Powell T., Maleyko I., Sangheli A., Ransome M., Isse M., Aromolaran O., Bholah H., Anbarasan J., Rehman S., Hu E., Timms S., Reynolds W., Hotchkies A., Misra V., Theocharidou L., Malik T., Janmohamed I., Carhart B., Khan A., Hullait R., Rylance A., Butt S., Leathes J., Philip Rajathasan T., Jeddy H., Kyaw H.A., Wong N., Karelia S., Clements J.M., Rainey M., Joshi N., Rahman A., Gallagher M., Rebuffa N., Abdelgalil R., Siaw Yen Lai R., Laurence N., Thomas S., Green C., Frostick R., Khera R., Povey M., Wong H.L., McCusker C., Hlukha L., Pike G., Kamel F., Thakkar R., Donaldson C., Sequeira Campos M., Armitage M.N., Hussain A.S., Hardy B., Hassan Serry M.Y., Bradbury M., Osunronbi T., Tam L.Y.C., Khanan Kaabneh A., Lawther J., Fisher P., Tribedi T., Moosa A., Ramdin A., Goble M., Downs E., Wheldon L., Baggus E., Mandal A., Nayeem A., Ahmed S., Fradley W., Wilson C., Gallagher S., Criswell T., Ward J., Mukkavilli A., Stubbs B., Fordyce W., Suchdev N., Wei Lim S., Sookramanien S.R., Chan A., Bointas G., Paul M., Ward K.L., Bagnall M., Pherwani S.A., Wang K., Mitchell L., Heyworth J., Ayyar S., Polson R., Mackenzie E., Doyle N., Habib Z., Zardab M., Sartaj F., Farooq H., Tabibi M., Drury D.J., James S.J., Barnett R., Teasdale A.B., Richardson E.T.J., Thomas D.A., Williams R.L., Najabat-Lattif H.F., Cahya E., Lou G., Coyle M., Homyer K., Zhu L.Y., Woods M., Chang J., O'Callaghan H., Suchett-Kaye I., Mihailidis T.H., Alawattegama H., Seite E., Barrett A., Riordan E., Lam W., Dowdeswell M., Mulvenna C., Awokoya O., Gurowich L., Dhera K., Hayat S., Tincknell L., Spazzapan M., Teeling F., Sysum K., Latter J., Latter M., Khan S., Guruswamy M., Beedham W., Brazier E., Elghobashy M., Bajaj M., Mann H., Etel E., Woodmass M., Hayden H., Ali Y., Husain S., Arnold A., Pedersen A.C., Cunha P., Ahmed M., Al Zawawi S., Kudva V., Theodoropoulou K., Miscampbell M., Robinson A.V., Johnston J., Dharni A., Lamb S., Westerman T., Evans E., Campbell L., Gillespie M., Cheong C.M., Kulathevanayagam K., Varghese A., Ike S.I., Chu T.S.M., Baljer B., Mogg J.A.W., Rai P., Claireaux H.A., Williams M., Smillie R., Goetz J., Appleby E., Fadipe T., Vaughan-Burleigh S., Puri G., Hussain P., Flather R., Cutler A., Pathak S., Sheldon J., Collicott T., al-Ausi M., Jovaisaite A., Shah S.M., Khalid N., Gutmann D., Davison S., Alame Y.J., Syed L., Owen W.J., Ahsan S.D., Anthony-Uzoeto U., Macleod Hall C., Zheng S., Wynter K., James C., Sapre D., Ghosh R., Baird J., Cockburn L., Blackwood O., Simpson W., Jeong S., Bishop S., Bate R., Hobson C., Adam A.H., Redclift C., Do J., Adeleye O., Poli F., Batterham A., Brown S., Parekh J.N., Clay W., Pieri K., Jackson A., Saxena A., Gurung B., Oyebola T., O'Brien F., Djeugam B., Gardezi S., Ul-Hasan S., Martin-Hernandez M.P., Sisley M., Modi S., Antakia R., Elbayouk A., Soh Y.J., Mather J., Yusuf Z., Al-Sarraf Z., Naja M., Rassool S.B., Convill J., Nikookam Y., Warsame A., Pace C., Kiandee M., Ridwan R., Carey C., Hirri F., McMillan M.J.A., Ling J.J., Pendelbury L., Kerimzade K., Tang A., Howard E.O., Humayun S., Wadsworth O.J., Tan K., Abdelhameed F., Haglund C., Radnaeva I., Hu N., Rambhatla S., Waldron D., Madahar P., Malik S., Meney L.C., Ibrahim I., Kang C.K., Chiu J.Z.J., Livie V., Ibrahim 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Gadhvi A., Grant R., Lewsey J., Morris A., Martin H., McClarty C., Sanyal S., Alsaif A., Palkhi A., Bhopal S., Vishnu K S., Papanikolaou A., Mitra A., Nur A., Ali F., Burford C., Huq T., Irwin E., Matthews L., Ngu W.S., Hosfield T., Muneeb F., Page O., Zeb E., Al-Azzawi A., McIntosh J., Vucicevic A., Hughes M., Brooks L., Fanibi B., Dixon M., Njoku P., Morris D., Jobson J., Chowdhury H., Alawode D.O.T., Wynell-Mayow W., Udayachandran V., Alsoof D., Ekert J., Joseph N., Zulkefley N., Hunt G., Christodoulou T., Wright O., Soman S., Jamal M., Beqiri S., Borgas P., Christie S., Pereira F., Browne S., Yiu J., Dworkin A., Brayley J., Palmer A., Charalambos M., Jones C.J., Toner S., Cowden R., Lee L., Nicol P., Holman O., Imtiaz M., Albert V., Leung S.P., Erotocritou M., Stroud R., Wilkin R., Thomson W., Mackee L., G N., Bei Y., Mckenna Favier S., Ibrahim A., Kler A., Reynolds L., Mohamed S.H., Majeed Y., Fakim B., Jones A., Liversedge G., Carrington Z., Windebank J., Izzarina A., Akbani U., Craven J., Aldarragi A., Harding S., Millward A., Bedford M., Gopalan V., Midgen A., Khadka P., Cheng O., Taneja S., Manobharath N., Kok J.Y., Lim D.W.E., Buick T., Boland M., Piya S., Devlin R., Fairfield C.J., George R.J., Rahi M., Zaman S., Hajiev S., Ross T., Crisp E., Thompson C., Charalambous A., Hollywood J.L., Hammond R.F.L., Matthews J., Mendonca V., Spinty J., Khan K., Cheng J., Glynn N., Muhammad U., Khan M., Anderson L., Mccormack K., Mak J., Patrawala S., Milinkovic N., Schofield R., Chauhan M., Hartley L., Hind J., Nelson L., Ratnasingham D., Whitehead T., Dimitriadis S., Marshall K., Flint E.J., Horner C., Heybourne A., Morgan H., Wickstone C., Panagiotou D., O'Connell E., Dean K., Iqbal R., Walsh L., Yu N., Rana N., Massie E., Ng J., Jung M., Lee Y.D., Harris M., White S., Boev B., Tonchev P., Prochazka V., Skalicky A., Ravn S., Ojakaar A., Dorr-Harim C., Koutserimpas C., Giraudo G., Armellini A., Ruzzenente A., Mazzeo C., De Padua C., Realis Luc A., Maroli A., Giani I., Cufari M.E., Vitali M., Gusai G.P., Quattromani R., Virgilio E., Berti S., Di Mola F.F., Papagni V., Tuminello F., Vittori L., Longheu A., Loche G.A., Braccio B., De Luca E., Resta G., Ancans G., Tamosiunas A., Petrulionis M., Andrejevic P., Stellingwerf M.E., Abdulrahman N., van de Pas K.G.H., Thomas G., Brandsma A.M., Davids J., Rottier S.J., de Roy van Zuidewijn D., Hawkins R., Ong H.I., Li Y., Desmond B., Winstanley J., Martins M., Americano M., Frade S., Senhorinho R., Peixoto R., Alves-Vale C., Lamas M., O'Connor D.B., Hoo M., Gopaul A., Scanlon K., O'Dwyer N., Jovanovic M., Panyko A., Van Vuuren S., Curchod P., Gaspar S., Imadalou L., Mutlu D., Akyol C., Uygur F.A., Eray I.C., Biyiklioglu O., Cetin M.F., Isik A.E., Karip B., Dogan H., Sarigul L., Tunc E., Aydin T., Bodur S., Karabulut K., Francis A.A., Al-hadithi A., To N., Lau I.S.F., Smith E., Mahapatra S., McAuliffe O., Imam L., Akram B., Hossaini S., Davies R., Ko M., Collins J., Pandya A., Reilly S., Archer J., Auty C., Roche C.D., Livie J., Chaudhry F.A., Ntakomyti E., Diallo R., Bylinski T., Wright J., Masiha E., Tung J., Shirazi B., Neilson A., Epton S., Patel N., Trussell S., Couldrey A., Donnelly C., Eftychiou S., Chapman, S. 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Geçim, Ie, Disçi, E, Haksal, Mc, Agarwal, T, Maxwell‐armstrong, C, Moug, Sj, Lund, Jn, Smart, Nj, Smith, Fm, Lee, Yj, Lai, Lt, Jun, Hj, Mendis, Dm, Robb, Pm, Lee, Hj, Wyche, Aab, Davis, Lt, Jayalath, Jmsn, Blefari, Nda, Goh, Yk, Beh, Yz, Dudi‐venkata, Nn, Borrow, Jl, Chua, Th, Tan, Rr, Ng, Sy, Britten‐jones, P, Pham, Hdv, Coulter‐nile, Smcj, Gosselink, Mp, Wang, Yl, Pös, M, Bartoš, M, Malý, O, Hanušová, M, Hurný, M, Riško, J, Treskoň, R, Pospíšil, M, Hlaváčová, L, Tomanová, D, Novický, R, Sobotková, K, šuta Kimle, K, Paclík, A, Jürgens‐lahnstein, J, Kristensen, Fp, Bønnerup, K, Højgaard Pedersen, J, Jepsen, Bn, Hillgaard, Tk, Erichsen, Sb, Nielsen, Cv, Madsen, Cp, Skejø, Cd, Aabling, Rr, Sørensen, J, Schöning, L, Simon, S CS, Thäwel, T, Seckler, Am, Athanasopoulos, Pg, Giuffrida, Mc, Billo, Me, Marrosu, Ag, Ruggiu, Mw, Antona, Ad, Bitonti, Mf, Romano, Fm, Pellicanò, Ga, Murru, Ml, Angelucci, Gp, Tenconi, Sm, Mura, Fa, Ruggiu, Gv, Mura, Ga, Perrone, Ba, Esposito, Lm, Marcianò, M, Aru, Ac, Figà, F, Truškovs, A, Machatschek, Mj, Wiemann, Am, Müller, Nl, Samalavicius, Ne, Poškus, E, Kryžauskas, M, Poškus, T, Looyen, R, Becker, Maj, Molder, L, Tissen, Ym, Vries, H, Smaalen, Tc, Veen, Oc, Dingemans, Sa, Brink, Lc, Vijgen, Ghej, Voort, Emf, Pool, A, Rest, Klc, Sluijpers, Nrf, Molenaar, Cjl, Gordinou de Gouberville, Mc, Mens, Ma, Hoeks, Em, Praag, Em, Smit, Mpcm, Lely, Sj, Stijns, Rch, Leow, Ty, Ruiter, A, Aarts, Cam, Jonge, J, Alqethami, Hj, Elst, Pc, Tissink, Mw, Grüter, A, Voeten, Dm, Boon, Cl, Franssen, Rjm, Jense, Mtf, Lau, Wk, Adams, Sib, Chen, Sy, Kim, Dh, Mclaughlin, Sjp, Chapman, Da, Mcintosh, Nd, Tewhaiti‐smith, J, Yam, St, Tomé, M, Santos, Tc, Lages, Rr, Sá, Tc, Bernardes, Fm, Cunha, Mf, Veiga, Dn, Loureiro, Ar, Torre, Ap, Paixão, I, Rocha, Af, Jervis, Mj, Paixão, V, Silva, Ag, Galvão, D, Mónica, I, Guimarães, N, Martins, Sf, Rocha‐melo, M, Patrício, J, Cinza, Am, Simões, J, Gonçalves, Jp, Guimarães, J, Martins, Ar, Lérias, R, Bártolo, J, Correia, Am, Martins, Pc, Jardim, Jam, Domingos, Sp, Baião, Jm, Lopes, Nmro, Jordão, Dm, Ângelo, Md, Caroço, T, Gomes, Jr, Monteiro, Rg, Colon, Lf, Dockry, É, Aly, Ak, Kang, Sj, Pentony, Ar, Piong, Cl, Eow, Sy, Kamath, Pj, Soh, Tbw, Dyer, Ah, Chee, Sy, Tan, Ixh, Jones, Mr, Al‐salihi, A, Ciubotaru, Ci, Radulović, R, Miloševic, K, Bojičić, J, Genčić, M, Janković, U, Sucháň, Pk, Dubovský, M, Sautter, Sc, Mcduling, Cr, Haller, Ml, Piotet, Lm, Kurtoglu, Gk, Sel, Ek, Isler, Vc, Demirkaya, Hc, Korkmaz, Hk, Pektas, Am, Güner, B, İşlek, Ec, Tombul, Hb, Boztuğ, Cy, Tınaz, A, Yılmaz, M, Akın, Fa, Başçavuş, M, Seker, Mc, Koçak, Zb, Karapinar, Ye, Köseoglu, E, Agca, Mh, Alim, Ye, Kürklü, Ö, Çalar, Sn, Kavar, Rc, Cevlik, Ad, Turk, Eg, Erdönmez, H, Gürsoy, F, Önsal, U, Özbek, M, Kasar, Pa, Özen, D, Ölmez, M, Sariçiçek, T, Tipi, Ou, Benli, Ge, Bilgili, Ac, Kiraz, In, Aksoy, Ab, Karagöz, E, Tümer, S, Abdulrahman, Smf, Kuyumcu, Of, Afsar, Hb, Guler, Se, Gul, Eb, Dossa, Saa, Mizan, Sr, Sahin, Az, Kilinç, A, Yumurtaci, Ö, Girit, Çagri, Yildirak, Mk, Güldag, A, Söyleyici, B, Aytin, Ye, Akay, Fe, Iskan, Ng, Sunay, Ao, Tie‐gill, T, Delaugere, Lp, Yeo, Yq, Aly, Mh, Dwyer‐hemmings, L, Bin Amran, Am, Kyaw, Ha, Clements, Jm, Wong, Hl, Armitage, Mn, Hassan Serry, My, Tam, Lyc, Sookramanien, Sr, Ward, Kl, Pherwani, Sa, Drury, Dj, James, Sj, Teasdale, Ab, Richardson, Etj, Thomas, Da, Williams, Rl, Najabat‐lattif, Hf, Zhu, Ly, Suchett‐kaye, I, Mihailidis, Th, Pedersen, Ac, Robinson, Av, Cheong, Cm, Ike, Si, Chu, Tsm, Mogg, Jaw, Claireaux, Ha, Vaughan‐burleigh, S, Al‐ausi, M, Shah, Sm, Alame, Yj, Owen, Wj, Ahsan, Sd, Anthony‐uzoeto, U, Adam, Ah, Parekh, Jn, Ul‐hasan, S, Martin‐hernandez, Mp, Soh, Yj, Al‐sarraf, Z, Rassool, Sb, Mcmillan, Mja, Ling, Jj, Howard, Eo, Wadsworth, Oj, Meney, Lc, Kang, Ck, Chiu, Jzj, Tan, Qj, Cross, Gwv, Shah, Dr, Ng, Mpe, Wong, Rtw, Rojoa, Dm, Ruddy, Cm, Hall, Jd, Hassane, Asi, Azhar, Aw, Tan, Tk, Kwak, Sy, Ong, Eh, Goolam‐mahomed, Z, Kirnon‐jackman, O, Lim, Qx, Yong, Sq, Chen, Jy, Sam, Zh, Goh, Yn, Muthukumar, Mg, Johnson, Ta, Williams, Ri, Honeyman, Si, Malcolm, Fl, Wilkerson, Ht, Chatterjee‐woolman, S, Ahmed, Wur, Kwan, Kwl, Sanders‐crook, L, Boh, Zy, English, Wj, Novotny, Sa, Chong, Jt, Lee, De, Embury‐young, Y, Clavé Llavall, A, Pang, Yl, Dellen, J, Al‐azzawi, A, Alawode, Dot, Wynell‐mayow, W, Christodoulou, T, Jones, Cj, Leung, Sp, Mohamed, Sh, Kok, Jy, Lim, Dwe, Fairfield, Cj, George, Rj, Hollywood, Jl, Hammond, Rfl, Flint, Ej, Lee, Yd, Skalický, A, Ojakäär, A, Dörr‐harim, C, Cufari, Me, Gusai, Gp, Di Mola, Ff, Loche, Ga, Stellingwerf, Me, Pas, Kgh, Brandsma, Am, Rottier, Sj, Roy van Zuidewijn, D, Ong, Hi, Alves‐vale, C, O'Connor, Db, Jovanović, M, Uygur, Fa, Eray, Ic, Çetin, Mf, Isik, Ae, Sarıgül, L, Francis, Aa, Al‐hadithi, A, Lau, Isf, Roche, Cd, and Chaudhry, Fa
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Male ,renal failure ,Time Factors ,medicine.medical_treatment ,Adult ,Aged ,Anti-Inflammatory Agents, Non-Steroidal ,Elective Surgical Procedures ,Female ,Humans ,Ileus ,Kaplan-Meier Estimate ,Middle Aged ,Patient Safety ,Postoperative Care ,Postoperative Complications ,Proportional Hazards Models ,Prospective Studies ,Recovery of Function ,Treatment Outcome ,Colectomy ,Proctectomy ,Anti-Inflammatory Agents ,colorectal surgery ,ileus ,non-steroidal anti-inflammatory drugs ,NSAIDS ,030230 surgery ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Prospective cohort study ,Colorectal ,RISK ,Hazard ratio ,Acute kidney injury ,Colorectal surgery ,NSAID ,030220 oncology & carcinogenesis ,Non-Steroidal ,Cohort study ,colorectal Surgery, ileus, non-steroidal anti-inflammatory drugs ,medicine.medical_specialty ,Non‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery ,ACUTE KIDNEY INJURY ,anti-inflammatory agents ,03 medical and health sciences ,Internal medicine ,medicine ,Adverse effect ,non-steroidal anti-inflammatory drugs - ileus - colorectal surgery ,business.industry ,medicine.disease ,Settore MED/18 - Chirurgia Generale ,colorectal cancer ,Surgery ,business - Abstract
Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a centre-specific survey of compliance to enhanced recovery principles. Secondary safety outcomes included anastomotic leak rate and acute kidney injury.A total of 4164 patients were included, with a median age of 68 (i.q.r. 57-75) years (54·9 per cent men). Some 1153 (27·7 per cent) received NSAIDs on postoperative days 1-3, of whom 1061 (92·0 per cent) received non-selective cyclo-oxygenase inhibitors. After adjustment for baseline differences, the mean time to gastrointestinal recovery did not differ significantly between patients who received NSAIDs and those who did not (4·6 versus 4·8 days; hazard ratio 1·04, 95 per cent c.i. 0·96 to 1·12; P = 0·360). There were no significant differences in anastomotic leak rate (5·4 versus 4·6 per cent; P = 0·349) or acute kidney injury (14·3 versus 13·8 per cent; P = 0·666) between the groups. Significantly fewer patients receiving NSAIDs required strong opioid analgesia (35·3 versus 56·7 per cent; P 0·001).NSAIDs did not reduce the time for gastrointestinal recovery after colorectal surgery, but they were safe and associated with reduced postoperative opioid requirement.El ileo es frecuente tras cirugía colorrectal electiva y se asocia con un incremento de los eventos adversos y de la duración de la estancia hospitalaria. El objetivo fue evaluar el papel de los fármacos antiinflamatorios no esteroideos (non-steroidal anti-inflammatory drugs, NSAIDs) para reducir el ileo tras la cirugía. MÉTODOS: Estudio de cohortes prospectivo y multicéntrico efecuado por un grupo colaborativo dirigido por estudiantes y cirujanos en formación. Se incluyeron pacientes adultos sometidos a cirugía colorectal electiva entre enero y abril 2018. El resultado primario fue el tiempo hasta la recuperaciòn gastrointestinal, medido por una variable compuesta de función intestinal y tolerancia a la alimentación oral. El impacto de los NSAIDs se exploró utilizando un análisis de regresión de Cox, que incluía los resultados de una encuesta específica dirigida a los centros sobre la adherencia a los principios de la recuperación intensificada. Los resultados secundarios de seguridad incluyeron la dehiscencia anastomótica y la insuficiencia renal aguda.Se incluyeron 4.164 pacientes con una mediana de edad de 68 años (rango intercuartílico: 57-75; 54,9% varones). Un total de 1.153 (27,7%) pacientes fueron tratados con NSAIDs en los días postoperarorios 1-3, de los cuales 1.061 (92,0%) recibieron inhibidores no selectivos de la ciclooxigenasa. Tras los ajustes por las diferencias basales, el tiempo medio hasta la recuperación gastrointestinal no difería significativamente entre pacientes que recibieron o no recibieron NSAIDs (4,6 versus 4,8 días; cociente de riesgos instantáneos, hazard ratio, HR 1,04, i.c. del 95%: 0,96-1,12, P = 0,360). No hubo diferencias significativas en la tasa de dehiscencias anastomóticas (5,4% versus 4,6%; P = 0,349) o insuficiencia renal aguda (14,3% versus 13,8%; P = 0,666) entre los grupos. Sin embargo, significativamente menos pacientes de los que recibieron NSAIDs precisaron una analgesia intensa con opioides (35,3% versus 56,7%; P 0,001). CONCLUSIÓN: La administración de NSAIDs no redujo el tiempo hasta la recuperación gastrointestinal tras cirugía colorrectal, pero fueron seguros y se asociaron con una reducción en la necesidad de opioides postoperarorios.
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- 2019
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4. Adherence to Guidelines for Diagnosis, Staging, and Treatment for Gastric Cancer in Italy According to the View of Surgeons and Patients.
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Fabbi M, Milani MS, Giacopuzzi S, De Werra C, Roviello F, Santangelo C, Galli F, Benevento A, and Rausei S
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Background : Despite the strong declining trends in incidence and mortality over the last decades, gastric cancer (GC) is still burdened with high mortality, even in high-income countries. To improve GC prognosis, several guidelines have been increasingly published with indications about the most appropriate GC management. The Italian Society of Digestive System Pathology (SIPAD) and Gastric Cancer Italian Research Group (GIRCG) designed a survey for both surgeons and patients with the purpose of evaluating the degree of application and adherence to guidelines in GC management in Italy. Materials and Methods : Between January and May 2022, a questionnaire has been administered to a sample of Italian surgeons and, in a simplified version, to members of the Patient Association "Vivere Senza Stomaco" (patients surgically treated for GC between 2008 and 2021) to investigate the diagnosis, staging, and treatment issues. Results : The survey has been completed by 125 surgeons and 125 patients. Abdominal CT with gastric hydro-distension before treatment was not widespread in both groups (47% and 42%, respectively). The rate of surgeons stating that they do not usually perform minimally invasive gastrectomy was 15%, but the rate of patients who underwent a minimally invasive approach was 22% (between 2011 and 2022). The percentage of surgeons declaring to perform extended lymphadenectomy (>D2) was 97%, although a limited lymph node dissection rate was observed in about 35% of patients. Conclusions : This survey shows several important discrepancies from surgical attitudes declared by surgeons and real data derived from the reports available to the patients, suggesting heterogeneous management in clinical practice and, thus, a not rigorous adherence to the guidelines.
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- 2024
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5. The weekend effect on the provision of Emergency Surgery before and during the COVID-19 pandemic: case-control analysis of a retrospective multicentre database.
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Tebala GD, Milani MS, Cirocchi R, Bignell M, Bond-Smith G, Lewis C, Agnoletti V, Catarci M, Di Saverio S, Luridiana G, Catena F, Scatizzi M, and Marini P
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- Case-Control Studies, Hospital Mortality, Humans, Retrospective Studies, COVID-19 epidemiology, Pandemics
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Introduction: The concept of "weekend effect", that is, substandard healthcare during weekends, has never been fully demonstrated, and the different outcomes of emergency surgical patients admitted during weekends may be due to different conditions at admission and/or different therapeutic approaches. Aim of this international audit was to identify any change of pattern of emergency surgical admissions and treatments during weekends. Furthermore, we aimed at investigating the impact of the COVID-19 pandemic on the alleged "weekend effect"., Methods: The database of the CovidICE-International Study was interrogated, and 6263 patients were selected for analysis. Non-trauma, 18+ yo patients admitted to 45 emergency surgery units in Europe in the months of March-April 2019 and March-April 2020 were included. Demographic and clinical data were anonymised by the referring centre and centrally collected and analysed with a statistical package. This study was endorsed by the Association of Italian Hospital Surgeons (ACOI) and the World Society of Emergency Surgery (WSES)., Results: Three-quarters of patients have been admitted during workdays and only 25.7% during weekends. There was no difference in the distribution of gender, age, ASA class and diagnosis during weekends with respect to workdays. The first wave of the COVID pandemic caused a one-third reduction of emergency surgical admission both during workdays and weekends but did not change the relation between workdays and weekends. The treatment was more often surgical for patients admitted during weekends, with no difference between 2019 and 2020, and procedures were more often performed by open surgery. However, patients admitted during weekends had a threefold increased risk of laparoscopy-to-laparotomy conversion (1% vs. 3.4%). Hospital stay was longer in patients admitted during weekends, but those patients had a lower risk of readmission. There was no difference of the rate of rescue surgery between weekends and workdays. Subgroup analysis revealed that interventional procedures for hot gallbladder were less frequently performed on patients admitted during weekends., Conclusions: Our analysis revealed that demographic and clinical profiles of patients admitted during weekends do not differ significantly from workdays, but the therapeutic strategy may be different probably due to lack of availability of services and skillsets during weekends. The first wave of the COVID-19 pandemic did not impact on this difference., (© 2022. The Author(s).)
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- 2022
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6. Emergency surgery admissions and the COVID-19 pandemic: did the first wave really change our practice? Results of an ACOI/WSES international retrospective cohort audit on 6263 patients.
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Tebala GD, Milani MS, Bignell M, Bond-Smith G, Lewis C, Cirocchi R, Di Saverio S, Catena F, Scatizzi M, and Marini P
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- Hospitalization, Humans, Retrospective Studies, SARS-CoV-2, COVID-19, Pandemics
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Introduction: The COVID-19 pandemic is having a deep impact on emergency surgical services, with a significant reduction of patients admitted into emergency surgical units world widely. Reliable figures of this reduction have not been produced yet. Our international audit aimed at giving a precise snapshot of the absolute and relative changes of emergency surgical admissions at the outbreak of the pandemic., Materials and Methods: Datasets of patients admitted as general surgical emergencies into 45 internationally distributed emergency surgical units during the months of March and April 2020 (Covid-19 pandemic outbreak) were collected and compared with those of patients admitted into the same units during the months of March and April 2019 (pre-Covid-19). Primary endpoint was to evaluate the relative variation of the presentation symptoms and discharge diagnoses between the two study periods. Secondary endpoint was to identify the possible change of therapeutic strategy during the same two periods., Results: Forty-five centres participated sent their anonymised data to the study hub, for a total of 6263 patients. Of these, 3810 were admitted in the pre-Covid period and 2453 in the Covid period, for a 35.6% absolute reduction. The most common presentation was abdominal pain, whose incidence did not change between the two periods, but in the Covid period patients presented less frequently with anal pain, hernias, anaemia and weight loss. ASA 1 and low frailty patients were admitted less frequently, while ASA>1 and frail patients showed a relative increase. The type of surgical access did not change significantly, but lap-to-open conversion rate halved between the two study periods. Discharge diagnoses of appendicitis and diverticulitis reduced significantly, while bowel ischaemia and perianal ailments had a significant relative increase., Conclusions: Our audit demonstrates a significant overall reduction of emergency surgery admissions at the outbreak of the Covid-19 pandemic with a minimal change of the proportions of single presentations, diagnoses and treatments. These findings may open the door to new ways of managing surgical emergencies without engulfing the already busy hospitals., (© 2022. The Author(s).)
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- 2022
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7. Importance of the Duodenal Window and Fredet's Fascia in Laparoscopic Right Hemicolectomy: Technical Note.
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Tebala GD, Di Saverio S, Gallo G, Cirocchi R, Milani MS, and Bond-Smith G
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- Colectomy, Fascia, Humans, Lymph Node Excision, Colonic Neoplasms surgery, Laparoscopy, Mesocolon surgery
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Background: Laparoscopic right hemicolectomy requires a precise anatomical dissection to mobilise the right and proximal transverse mesocolon, following the avascular fusion planes of Toldt and Fredet. Fredet's plane is crucial to the preparation of the origin of vessels. Easy access to Fredet's and Toldt's fasciae can be obtained through the "duodenal window", a flimsy area of the root of the proximal transverse mesocolon, the margins of which are the right border of the superior mesenteric pedicle, the ileocolic pedicle, the right colic pedicle and the marginal artery., Method: We propose that dissection of the duodenal window should be the first step in laparoscopic right hemicolectomy, to obtain easy access to the duodenopancreatic plane and prepare the fascia., Results: This "duodenal window-first" technique has been applied in 45 laparoscopic right hemicolectomies and 14 laparoscopic extended right hemicolectomies, with only two conversions to open surgery. The duodenal window was easily identified in all but 3 cases with significant visceral obesity. No significant intra- or postoperative morbidity was recorded in these cases and the median postoperative length of stay was 4 days. All resections were R0 and an adequate number of retrieved lymph nodes were obtained in almost all cases., Conclusion: The duodenal window-first approach is a feasible and safe technique to standardise the first steps of radical laparoscopic right hemicolectomy, allowing prompt and complete anatomical identification and dissection.
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- 2021
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8. Production optimization of passion fruit peel flour and its incorporation into dietary food.
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Garcia MV, Milani MS, and Ries EF
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- Chemical Phenomena, Dietary Fiber analysis, Dietary Proteins analysis, Food Microbiology, Food Packaging, Food Storage, Nutritive Value, Taste, Triticum chemistry, Flour analysis, Food Handling, Passiflora chemistry
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This study aimed to obtain passion fruit peel flour and incorporate it as an ingredient in the development of dietary cookies. Drying proceeded by an experimental design with variable temperature and time and storage trial of the obtained flour was conducted in plastic packaging under optimized conditions (90 ℃/11 h) for 90 days. The passion fruit peel flour was incorporated into cookies at three levels (10, 20, and 30%) to replace wheat flour. Chemical composition, microbiological quality, and acceptance of sensory attributes of the cookies were determined. The formulations tested had significantly higher mean contents of ash and crude fiber (p < 0.05) and showed adjusted microbiological standards. Acceptance of the appearance, aroma, and flavor attributes were similar (p > 0.05) in all formulations. The results show the viability of optimized production of alternative flour (30% of passion fruit peel flour) from agro-industrial waste and the potential of the flour as an ingredient for the nutritional enrichment of dietary foods.
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- 2020
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9. [Primary failure of eruption: diagnostics, treatment, casus and review of literature].
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Milani MS and Kuijpers MA
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- Child, Child, Preschool, Humans, Open Bite rehabilitation, Tooth, Impacted diagnosis, Tooth, Impacted therapy, Molar physiology, Tooth Eruption physiology, Tooth, Unerupted diagnosis, Tooth, Unerupted therapy
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Primary failure of eruption is a rare eruption disorder of above all, the permanent second and sometimes the first molars. It is characterized by infra occlusion of the molars resulting in a severe lateral open bite. Primary failure of eruption is a disorders which affects all molars distal to the most mesial involved tooth. Diagnosis is possible both clinically and with radiographs. A panoramic radiograph combined with clinical findings of impaction or infra occlusion can confirm the suspicion of primary failure of eruption. Primary failure of eruption cannot be treated as other eruption disturbances are. The teeth do not respond to orthodontic force. Exposure of the molar and orthodontic traction of a molar affected by primary failure of eruption is discouraged. Observation and extraction, in case the primary failure of eruption poses a risk to the healthy dentition, are the only two treatment options for young patients. Additional treatment of this eruption disorder should be carried out at an adult age and consists of prosthetic closure of the open bite.
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- 2014
10. Genetic variability of Paecilomyces fumosoroseus isolates revealed by molecular markers.
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Tigano-Milani MS, Honeycutt RJ, Lacey LA, Assis R, McClelland M, and Sobral BW
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- Animals, Base Sequence, DNA, Fungal genetics, Genetic Markers, Molecular Sequence Data, Paecilomyces classification, Phylogeny, Polymerase Chain Reaction, RNA, Fungal genetics, RNA, Transfer, Genetic Variation, Paecilomyces genetics
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Paecilomyces fumosoroseus (Deuteromycotina:Hyphomycetes) is a fungus that is potentially useful for the bio-control of economically important agricultural pests, such as whitefly (Bemisia tabaci). Arbitrarily primed PCR and PCR with tRNA consensus primers were used to analyze genetic variability among 27 P. fumosoroseus isolates, 15 of which came from the same host, B. tabaci, one P. lilacinus isolate, used as an outgroup, 9 previously unidentified Paecilomyces isolates. Fifteen 10-mer oligonucleotide primers of arbitrary sequence revealed 322 scorable binary characters. Principal coordinates and cluster analysis of characters showed that most of the P. fumosoroseus and Paecilomyces sp. isolates were in three phenetic groups with > 65% internal similarity. Two of the three arbitrary phenetic groups were closely related (76% similarity) with the third group quite different (only 14% similarity) from the first two. The phenetic groups did not correlate with geographical origin or host species. Genetic variability of isolates infecting whitefly in Florida was detected. Isolates from B. tabaci were represented in two of the three groups, and different genotypes were identified even when they were isolated from an epizootic population in India and Pakistan. There was no evidence of host-specific selection of genotypes, as has been shown in other entomopathogenic fungi. Three isolates morphologically classified as P. fumosoroseus were clustered in a phenetic group which displayed only 14% similarity to the other isolates of this species. Seven isolated that presented problems for morphological classification were found to be similar or, in three cases, identical to other P. fumosoroseus isolates that dit not present problems for morphological classification.(ABSTRACT TRUNCATED AT 250 WORDS)
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- 1995
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11. DNA markers for differentiating isolates of Paecilomyces lilacinus.
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Tigano-Milani MS, Samson RA, Martins I, and Sobral BW
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- Base Sequence, Consensus Sequence, DNA Primers, Molecular Sequence Data, Paecilomyces isolation & purification, Polymerase Chain Reaction, RNA, Fungal genetics, RNA, Transfer genetics, DNA, Fungal analysis, Genome, Fungal, Paecilomyces classification, Paecilomyces genetics, Phylogeny
- Abstract
Paecilomyces lilacinus is an agent for the potential biological control of soil nematodes. Arbitrarily primed PCR was used to fingerprint the genomes of 28 isolates of this fungus. Most (72%) of the isolates originated from soil of different regions of Brazil. Fourteen 10-mer oligonucleotide primers of arbitrary sequence revealed 293 scorable binary characters. Distinct genotypes were obtained for each isolate. Cluster analysis showed a high level of variability among these genotypes. The similarity among pairwise comparisons of the isolates varied from 84.3% to 7.6%, with a mean of 63.5%. No clearly defined phenetic groups were identified by cluster or multivariate analyses. No correlation with geographical origin or host was detected. In addition, PCR with four pairs of consensus tRNA gene primers was performed on a subsample of 12 P. lilacinus isolates, three P. farinosus isolates, two P. fumosoroseus isolates, and one isolate of P. amoenoroseus. An inferred phylogeny based on 112 binary characters obtained by tRNA-PCR showed a monophyletic group which contained most of the P. lilacinus isolates. In contrast, three isolates of P. farinosus were not in a monophyletic group under the inferred phylogeny. These results suggest that tRNA fingerprinting could provide a valuable tool which could be used to develop the molecular taxonomy of Paecilomyces, as morphological characteristics of asexual structures cannot entirely resolve species.
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- 1995
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