1. Cataract in the chronically exposed residents of the Techa riverside villages.
- Author
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Mikryukova LD and Akleyev AV
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Cataract etiology, Child, Child, Preschool, Cohort Studies, Dose-Response Relationship, Radiation, Female, Humans, Infant, Male, Middle Aged, Radiation Injuries etiology, Russia, Time Factors, Young Adult, Cataract epidemiology, Radiation Exposure adverse effects, Radiation Injuries epidemiology, Rivers
- Abstract
The present study is based on a retrospective analysis of archive data of the Clinical Department of the Urals Research Center for Radiation Medicine that has been established to examine and treat accidentally exposed residents of the Urals Region. All individuals included in this study were examined by an ophthalmologist. The study of cataract incidence has been conducted retrospectively for the period from 1951 till 2000 among chronically exposed residents of the Techa riverside villages (6343 persons). Individual accumulated absorbed doses to soft tissues (analogue of eye dose) reached 1.18 Gy (mean 0.12 Gy) while for 88.9% of the study group the dose did not exceed 0.1 Gy. There was no evidence of the influence of low-dose and low-dose rate on cataract incidence. Excess relative risk of cataract formation per 1 Gy was 0.40 (95% CI -0.43; 1.47). It is noted that 15% of all excess cases were registered in persons with soft tissue dose above 0.3 Gy, though their fraction among all examined persons was only 4.1%. Risk of cataract development significantly increased in exposed individuals with retinal angiosclerosis, diabetes and arterial hypertension.
- Published
- 2017
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