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193 results on '"Miholic J"'

20. Die chirurgische Therapie des Kardiakarzinoms

Author

Miholic J

Subjects
Surgical therapy, medicine.medical_specialty, Text mining, business.industry, medicine.medical_treatment, medicine, Carcinoma, Adenocarcinoma, Gastrectomy, General Medicine, business, medicine.disease, Surgery
Published
2008
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21. LAPAROSCOPIC ANTIREFLUX SURGERY VS ESOMEPRAZOLE TREATMENT FOR CHRONIC GERD – THE LOTUS RANDOMIZED CLINICAL TRIAL

Author

Miholic J, Hubmann R, Danis J, Tack J, Lerut T, Piessevaux H, Devière J, Buset M, Chioccioli C, De Looze D, Demoulin JC, Louis E, Ghilain JM, Maisin JM, Funch Jensen P, Nielsen J, Christensen L, Antonsen H, Lauritsen K, Jess P, Wallin L, Naver L, Galmiche JP, Letessier E, Zerbib F, Bonaz B, Bost R, Delchier JC, Fein M, Maroske J, Ell C, Hölscher A, Zornig C, Schneider JH, Hüttl T, Büchler M, Wehrmann U, Kemen M, Layer P, Fuchs KH, Kemen S, Hüppe D, Oddsdóttir M, Thjodleifsson B, Bonavina L, Ancona E, Morino M, Pignata G, Giurissa A, Rossi M, Cestari R, Gooszen H, Hatlebakk J, Tefera S, Johnsen G, Jahnsen J, Sandstad O, Stallemo A, Florholmen J, Tollåli G, Engström C, Liedman B, Lundell L, Babbs C, Attwood S., ROSATI , RICCARDO, Miholic, J, Hubmann, R, Danis, J, Tack, J, Lerut, T, Piessevaux, H, Devière, J, Buset, M, Chioccioli, C, De Looze, D, Demoulin, Jc, Louis, E, Ghilain, Jm, Maisin, Jm, Funch Jensen, P, Nielsen, J, Christensen, L, Antonsen, H, Lauritsen, K, Jess, P, Wallin, L, Naver, L, Galmiche, Jp, Letessier, E, Zerbib, F, Bonaz, B, Bost, R, Delchier, Jc, Fein, M, Maroske, J, Ell, C, Hölscher, A, Zornig, C, Schneider, Jh, Hüttl, T, Büchler, M, Wehrmann, U, Kemen, M, Layer, P, Fuchs, Kh, Kemen, S, Hüppe, D, Oddsdóttir, M, Thjodleifsson, B, Bonavina, L, Ancona, E, Morino, M, Pignata, G, Giurissa, A, Rossi, M, Rosati, Riccardo, Cestari, R, Gooszen, H, Hatlebakk, J, Tefera, S, Johnsen, G, Jahnsen, J, Sandstad, O, Stallemo, A, Florholmen, J, Tollåli, G, Engström, C, Liedman, B, Lundell, L, Babbs, C, and Attwood, S.

Published
2011

31. Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication

Author

Miholic, J, Hoffmann, M, Holst, Jens Juul, Lenglinger, J, Mittlböck, M, Bergmann, H, Stacher, G, Miholic, J, Hoffmann, M, Holst, Jens Juul, Lenglinger, J, Mittlböck, M, Bergmann, H, and Stacher, G

Abstract

BACKGROUND: This study was designed to assess the relationship between gastric emptying of glucose solution and the ensuing plasma concentrations of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and glucose-dependent insulinotropic polypeptide (GIP) in patients having undergone fundoplication for gastroesophageal reflux (GERD).SUBJECTS AND METHODS: In 10 male patients the emptying of 50% glucose solution was determined scintigraphically and its relationship with plasma glucose, GLP-1, PYY, and GIP concentrations was studied before and 3 months after fundoplication.RESULTS: In the first 30 min after glucose ingestion, emptying was significantly (p = 0.048) faster after fundoplication than before. Emptying and GLP-1 and GIP correlated: the faster the emptying during the first 30 min the greater the concentrations integrated over that period (p = 0.04; p = 0.01; p = 0.02). Emptying and PYY concentrations were unrelated. In the 120-180 min. period, blood glucose concentrations were lower the faster the emptying in the initial 30 min (p = 0.06) and the entire 50-min recording period (p = 0.03) had been. The GLP-1 concentrations integrated over the first 30 min correlated inversely with the integrated plasma glucose during the third hour after ingestion (p = 0.004).CONCLUSIONS: After fundoplication, gastric emptying may, if accelerated in its initial phases, give rise to greater and earlier increases in plasma glucose, GLP-1, and GIP concentrations and thus to reactive hypoglycemia.

Published
2007

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