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1. Enhancing Performance of Cloud-based Software Applications with GraalVM and Quarkus

Author

Sipek, M., Muharemagic, D., Mihaljevic, B., and Radovan, A.

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

Increased complexity of network-based software solutions and the ever-rising number of concurrent users forced a shift of the IT industry to cloud computing. Conventional network software systems commonly based on monolithic application stack running on costly physical single-purpose servers are affected by significant problems of resource management, computing power distribution, and scalability.Such implementation is restricting applications to be reduced to smaller, independent services that can be more easily deployed, managed, and scaled dynamically; therefore, embellishing environmental uniformity across development, testing, and production. Current cloud-based infrastructure frequently runs on containers placed in Kubernetes or Docker-based cluster, and the system configuration is considerably different compared to the environment prevailed with common virtualizations. This paper discusses the usage of GraalVM, a polyglot high-performance virtual machine for JVM-based and other languages, combined with new Kubernetes native Java tailored stacked framework named Quarkus, formed from enhanced Java libraries. Moreover, our research explores GraalVMs creation of native images using Ahead-Of-Time (AOT) compilation and Quarkus deployment to Kubernetes. Furthermore, we examined the architectures of given systems, various performance variables, and differing memory usage cases within our academic testing environment and presented the comparison results of selected performance measures with other traditional and contemporary solutions, Comment: 6 pages, 5 figures, 1 table

Published
2021
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2. Exploring Aspects of Polyglot High-Performance Virtual Machine GraalVM

Author

Šipek, M., Mihaljević, B., and Radovan, A.

Subjects
Computer Science - Programming Languages
Abstract

Contemporary software often becomes vastly complex, and we are required to use a variety of technologies and different programming languages for its development. As interoperability between programming languages could cause high overhead resulting in a performance loss, it is important to examine how a current polyglot virtual machine with a compiler written in a high-level object-oriented language deals with it. OpenJDK's Project Metropolis presented the GraalVM, an open-source, high-performance polyglot virtual machine, mostly written in Java. This paper presents GraalVM's architecture and its features; furthermore, examining how it resolves common interoperability and performance problems. GraalVM makes software ecosystem productive when combining various programming languages, for example, Java, JavaScript, C/C++, Python, Ruby, R, and others. The vital part of GraalVM is the Graal compiler written in Java, which allows developers to maintain and optimize code faster, simpler, and more efficient, in comparison to traditional compilers in C/C++ languages. Graal can be used as a just-in-time (JIT) or as static, ahead-of-time (AOT) compiler. Graal is an aggressively optimizing compiler implementing common compiler optimizations, with emphasis on outstanding inlining and escape analysis algorithms. This paper compares Graal with some of the best-specialized competitors, and presents our results tested within an academic environment., Comment: 6 pages, 4 figures, 3 tables

Published
2021
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3. Distributed Applications in Gamification of the Learning Process

Author

Zagar, M., Sipek, M., Draskovic, N., and Mihaljevic, B.

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

Driven by the fact that many of us experienced softer or not-so-soft lockdown, the intention of a couple of instructors at our university was to develop a collaborative tool that could help in online delivery and gamification on two courses that are delivered in the Business and IT curriculums we are offering to our students. That tool could be described as a decentralized web application that simulates Internet marketing principles and helps in gamification of the learning process for our students. We planned our web application for Internet marketing simulation as the gamification of the learning process, which is one of the basics for active learning for Internet Marketing course for International Business students, to gain new class activities by online simulation competing in the field of Internet marketing principles; and for IT students in developing the Web application and also on adopting Blockchain technologies for the distributed reports which need to have a consensus of all teams included in the simulation. The proposed solution includes the design of business logic simulation and using four main digital marketing tools social networking, content creating and sharing, search engine marketing, and display advertising in use of such application for hands-on online class exercises., Comment: 5 pages, 3 figures, 1 table

Published
2021
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4. Next-generation Web Applications with WebAssembly and TruffleWasm

Author

Sipek, M., Muharemagic, D., Mihaljevic, B., and Radovan, A.

Subjects
Computer Science - Software Engineering
Abstract

In modern software development, the JavaScript ecosystem of various frameworks and libraries used to develop contemporary web applications presents many advantages. JavaScript is a widely known interpreted programming language, simple to learn and start development, and with numerous third-party libraries and extensions. However, with the rise of highly user-interactive websites and browser-based games, in some cases, JavaScripts executable engine could lack in performance. Therefore, developers could combine several other programming languages to create a polyglot user-interactive interoperable system to develop efficient modern web applications. The interoperability modules offer significant advantages but also present challenges in the execution due to high complexity and longer compilation times. This paper explores WebAssembly, a binary format compilation target with a low-level assembly-like language used for targeting from other programming languages. The binary format allows near-native performance level due to its compactness, as it prioritizes usage of low-level languages. Moreover, as a continuation of our previous research of the GraalVM ecosystem, we analyzed a guest language implementation of a WebAssembly based system, TruffleWasm, hosted on GraalVM and Truffle Java framework. This paper presents the architecture and review of the TruffleWasm within the GraalVM-based ecosystem as well as from performance test results within our academic environment., Comment: 6 pages, 3 figures

Published
2021
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5. Blockchain as an IoT intermediary

Author

Sipek, M., Zagar, M., and Mihaljevic, B.

Subjects
Computer Science - Cryptography and Security, Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

Blockchain technology provides a private, secure, transparent decentralized exchange of data. Also, blockchain is not limited to a particular area, but it has a wide range of applications and can be integrated into a variety of Internet interactive systems. For example, the Internet of Things (IoT), supply chain tracking, Electronic Health Records (EHR), digital forensics, identity management, trustless payments, and other key business elements will all benefit from its implementation. Next layer solutions such as Ethereum 2.0, Polkadot, Cardano, and other Web 3.0 technologies provide developers versatility. Moreover, these platforms utilize smart contracts which are similar to standard, traditionalized software during development but offer key utilities to end-users such as online wallets, secure data with transparent rules. Blockchain is receiving a lot of attention in educational technology (EduTech) as it aims to achieve a more transparent and multipurpose educational system. In addition to smart contract technology which defines how data should be registered, gathered and processed, blockchain can be used as an IoT intermediary for mobile usage. Therefore, we implemented an educational learning platform powered by blockchain technology to examine feasibility in industry and academic environment. In essence, this is a web application which is adapted to mobile platform and connected to blockchain for crucial data exchanges. In this paper we want to emphasize the potential of blockchain technology in multiple sectors as well as the need to really understand the underlying principles which are allowing disruptability of traditional centralized software solutions., Comment: 8 pages, 3 figures

Published
2021
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6. Application of Blockchain Technology for Educational Platform

Author

Sipek, M., Zagar, M., Mihaljevic, B., and Draskovic, N.

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

Nowadays, huge amounts of data are generated every second, and a quantity of that data can be defined as sensitive. Blockchain technology has private, secure, transparent and decentralized exchange of data as native. It is adaptable and can be used in a wide range of Internet-based interactive systems in academic and industrial settings. The essential part of programmable distributed ledgers such as Ethereum, Polkadot, Cardano and other Web 3.0 technologies are smart contracts. Smart contracts are programs executed on the global blockchain, the code is public as well as all of the data managed within the transactions, thus creating a system that is reliable and cannot be cheated if designed properly. In this paper, in order to make the educational system more transparent and versatile we will describe an educational learning platform designed as a distributed system., Comment: 6 pages, 1 figure

Published
2021

11. Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL

Author

Antic, D., Milic, N., Chatzikonstantinou, T., Scarfo, L., Otasevic, V., Rajovic, N., Allsup, D., Alonso Cabrero, A., Andres, M., Baile Gonzales, M., Capasso, A., Collado, R., Cordoba, R., Cuellar-Garcia, C., Correa, J. G., De Paoli, L., De Paolis, M. R., Del Poeta, G., Dimou, M., Doubek, M., Efstathopoulou, M., El-Ashwah, S., Enrico, A., Espinet, B., Farina, L., Ferrari, A., Foglietta, M., Lopez-Garcia, A., Garcia-Marco, J. A., Garcia-Serra, R., Gentile, Marino, Gimeno, E., da Silva, M. G., Gutwein, O., Hakobyan, Y. K., Herishanu, Y., Hernandez-Rivas, J. A., Herold, T., Itchaki, G., Jaksic, O., Janssens, A., Kalashnikova, O. B., Kalicinska, E., Kater, A. P., Kersting, S., Koren-Michowitz, M., Labrador, J., Lad, D., Laurenti, Luca, Fresa, Alberto, Levin, M. -D., Mayor Bastida, C., Malerba, L., Marasca, R., Marchetti, M., Marquet, J., Mihaljevic, B., Milosevic, I., Miras, F., Morawska, M., Motta, M., Munir, T., Murru, R., Nunes, R., Olivieri, J., Pavlovsky, M. A., Piskunova, I., Popov, V. M., Quaglia, F. M., Quaresmini, G., Reda, G., Rigolin, G. M., Shrestha, A., Simkovic, M., Smirnova, S., Spacek, M., Sportoletti, P., Stanca, O., Stavroyianni, N., Te Raa, D., Tomic, K., Tonino, S., Trentin, L., Van Der Spek, E., van Gelder, M., Varettoni, M., Visentin, A., Vitale, C., Vukovic, Vladimir, Wasik-Szczepanek, E., Wrobel, T., Segundo, L. Y. S., Yassin, M., Coscia, M., Rambaldi, A., Montserrat, E., Foa, Robin, Cuneo, A., Carrier, M., Ghia, P., Stamatopoulos, K., Gentile M., Laurenti L. (ORCID:0000-0002-8327-1396), Fresa A., Vukovic V. (ORCID:0000-0002-9561-7825), Foa R., Antic, D., Milic, N., Chatzikonstantinou, T., Scarfo, L., Otasevic, V., Rajovic, N., Allsup, D., Alonso Cabrero, A., Andres, M., Baile Gonzales, M., Capasso, A., Collado, R., Cordoba, R., Cuellar-Garcia, C., Correa, J. G., De Paoli, L., De Paolis, M. R., Del Poeta, G., Dimou, M., Doubek, M., Efstathopoulou, M., El-Ashwah, S., Enrico, A., Espinet, B., Farina, L., Ferrari, A., Foglietta, M., Lopez-Garcia, A., Garcia-Marco, J. A., Garcia-Serra, R., Gentile, Marino, Gimeno, E., da Silva, M. G., Gutwein, O., Hakobyan, Y. K., Herishanu, Y., Hernandez-Rivas, J. A., Herold, T., Itchaki, G., Jaksic, O., Janssens, A., Kalashnikova, O. B., Kalicinska, E., Kater, A. P., Kersting, S., Koren-Michowitz, M., Labrador, J., Lad, D., Laurenti, Luca, Fresa, Alberto, Levin, M. -D., Mayor Bastida, C., Malerba, L., Marasca, R., Marchetti, M., Marquet, J., Mihaljevic, B., Milosevic, I., Miras, F., Morawska, M., Motta, M., Munir, T., Murru, R., Nunes, R., Olivieri, J., Pavlovsky, M. A., Piskunova, I., Popov, V. M., Quaglia, F. M., Quaresmini, G., Reda, G., Rigolin, G. M., Shrestha, A., Simkovic, M., Smirnova, S., Spacek, M., Sportoletti, P., Stanca, O., Stavroyianni, N., Te Raa, D., Tomic, K., Tonino, S., Trentin, L., Van Der Spek, E., van Gelder, M., Varettoni, M., Visentin, A., Vitale, C., Vukovic, Vladimir, Wasik-Szczepanek, E., Wrobel, T., Segundo, L. Y. S., Yassin, M., Coscia, M., Rambaldi, A., Montserrat, E., Foa, Robin, Cuneo, A., Carrier, M., Ghia, P., Stamatopoulos, K., Gentile M., Laurenti L. (ORCID:0000-0002-8327-1396), Fresa A., Vukovic V. (ORCID:0000-0002-9561-7825), and Foa R.

Abstract

Background: Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to COVID-19 related poor outcomes, including thrombosis and death, due to the advanced age, the presence of comorbidities, and the disease and treatment-related immune deficiency. The aim of this study was to assess the risk of thrombosis and bleeding in patients with CLL affected by severe COVID-19. Methods: This is a retrospective multicenter study conducted by ERIC, the European Research Initiative on CLL, including patients from 79 centers across 22 countries. Data collection was conducted between April and May 2021. The COVID-19 diagnosis was confirmed by the real-time polymerase chain reaction (RT-PCR) assay for SARS-CoV-2 on nasal or pharyngeal swabs. Severe cases of COVID-19 were defined by hospitalization and the need of oxygen or admission into ICU. Development and type of thrombotic events, presence and severity of bleeding complications were reported during treatment for COVID-19. Bleeding events were classified using ISTH definition. STROBE recommendations were used in order to enhance reporting. Results: A total of 793 patients from 79 centers were included in the study with 593 being hospitalized (74.8%). Among these, 511 were defined as having severe COVID: 162 were admitted to the ICU while 349 received oxygen supplementation outside the ICU. Most patients (90.5%) were receiving thromboprophylaxis. During COVID-19 treatment, 11.1% developed a thromboembolic event, while 5.0% experienced bleeding. Thrombosis developed in 21.6% of patients who were not receiving thromboprophylaxis, in contrast to 10.6% of patients who were on thromboprophylaxis. Bleeding episodes were more frequent in patients receiving intermediate/therapeutic versus prophylactic doses of low-molecular-weight heparin (LWMH) (8.1% vs. 3.8%, respectively) and in elderly. In multivariate analysis, peak D-dimer level and C-reactive protein to albumin ratio were poor prognostic factors for thrombosis occu

Published
2022

15. Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL

Author

Antic D, Milic N, Chatzikonstantinou T, Scarfò L, Otasevic V, Rajovic N, Allsup D, Alonso Cabrero A, Andres M, Baile Gonzales M, Capasso A, Collado R, Cordoba R, Cuéllar-García C, Correa JG, De Paoli L, De Paolis MR, Del Poeta G, Dimou M, Doubek M, Efstathopoulou M, El-Ashwah S, Enrico A, Espinet B, Farina L, Ferrari A, Foglietta M, Lopez-Garcia A, García-Marco JA, García-Serra R, Gentile M, Gimeno E, da Silva MG, Gutwein O, Hakobyan YK, Herishanu Y, Hernández-Rivas JÁ, Herold T, Itchaki G, Jaksic O, Janssens A, Kalashnikova OB, Kalicińska E, Kater AP, Kersting S, Koren- Michowitz M, Labrador J, Lad D, Laurenti L, Fresa A, Levin MD, Mayor Bastida C, Malerba L, Marasca R, Marchetti M, Marquet J, Mihaljevic B, Milosevic I, Mirás F, Morawska M, Motta M, Munir T, Murru R, Nunes R, Olivieri J, Pavlovsky MA, Piskunova I, Popov VM, Quaglia FM, Quaresmini G, Reda G, Rigolin GM, Shrestha A, Šimkovič M, Smirnova S, Špaček M, Sportoletti P, Stanca O, Stavroyianni N, Te Raa D, Tomic K, Tonino S, Trentin L, Van Der Spek E, van Gelder M, Varettoni M, Visentin A, Vitale C, Vukovic V, Wasik-Szczepanek E, Wróbel T, Segundo LYS, Yassin M, Coscia M, Rambaldi A, Montserrat E, Foà R, Cuneo A, Carrier M, Ghia P, Stamatopoulos K.

Subjects
Age, Anticoagulation therapy, Bleeding, CLL, COVID-19, D-dimer, LMWH, Thromboprophylaxis, Thrombosis
Abstract

Background: Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to COVID-19 related poor outcomes, including thrombosis and death, due to the advanced age, the presence of comorbidities, and the disease and treatment- related immune deficiency. The aim of this study was to assess the risk of thrombosis and bleeding in patients with CLL affected by severe COVID-19. Methods: This is a retrospective multicenter study conducted by ERIC, the European Research Initiative on CLL, including patients from 79 centers across 22 countries. Data collection was conducted between April and May 2021. The COVID-19 diagnosis was confirmed by the real-time polymerase chain reaction (RT-PCR) assay for SARS- CoV-2 on nasal or pharyngeal swabs. Severe cases of COVID-19 were defined by hospitalization and the need of oxygen or admission into ICU. Development and type of thrombotic events, presence and severity of bleeding complications were reported during treatment for COVID-19. Bleeding events were classified using ISTH definition. STROBE recommendations were used in order to enhance reporting. Results: A total of 793 patients from 79 centers were included in the study with 593 being hospitalized (74.8%). Among these, 511 were defined as having severe COVID: 162 were admitted to the ICU while 349 received oxygen supplementation outside the ICU. Most patients (90.5%) were receiving thromboprophylaxis. During COVID-19 treatment, 11.1% developed a thromboembolic event, while 5.0% experienced bleeding. Thrombosis developed in 21.6% of patients who were not receiving thromboprophylaxis, in contrast to 10.6% of patients who were on thromboprophylaxis. Bleeding episodes were more frequent in patients receiving intermediate/therapeutic versus prophylactic doses of low-molecular-weight heparin (LWMH) (8.1% vs. 3.8%, respectively) and in elderly. In multivariate analysis, peak D-dimer level and C- reactive protein to albumin ratio were poor prognostic factors for thrombosis occurrence (OR = 1.022, 95%CI 1.007‒1.038 and OR = 1.025, 95%CI 1.001‒1.051, respectively), while thromboprophylaxis use was protective (OR = 0.199, 95%CI 0.061‒0.645). Age and LMWH intermediate/therapeutic dose administration were prognostic factors in multivariate model for bleeding (OR = 1.062, 95%CI 1.017-1.109 and OR = 2.438, 95%CI 1.023-5.813, respectively). Conclusions: Patients with CLL affected by severe COVID-19 are at a high risk of thrombosis if thromboprophylaxis is not used, but also at increased risk of bleeding under the LMWH intermediate/therapeutic dose administration.

Published
2022

34. PB1908 THE SIGNIFICANCE OF THE INTERNATIONAL PROGNOSTIC INDEX FOR CHRONIC LYMPHOCYTIC LEUKEMIA (CLL-IPI) IN SERBIAN CLL PATIENTS

Author

Vukovic, V., primary, Antic, D., additional, Bukumiric, Z., additional, Karan-Djurasevic, T., additional, Dencic-Fekete, M., additional, Djurasinovic, V., additional, Tomic, K., additional, Otasevic, V., additional, Kraguljac-Kurtovic, N., additional, Tosic, N., additional, Pavlovic, S., additional, and Mihaljevic, B., additional

Published
2019
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39. Primary Intestinal Hodgkin Lymphoma Mimicking Intraabdominal Abscess in a Renal Transplant Recipient: A Case Report

Author

Mihaljevic B, Antic D, Kerkez M, Djordjevic, Lezaic, Perunicic Jovanovic M, Vukovic, and Zaric N

Subjects
Male, Cancer Research, medicine.medical_specialty, Pathology, Abdominal Abscess, Population, 030230 surgery, Plasma cell, Intraabdominal abscess, Gastroenterology, Post-transplant lymphoproliferative disorder, Diagnosis, Differential, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal medicine, Intestinal Neoplasms, Medicine, Humans, Abscess, education, Kidney transplantation, education.field_of_study, business.industry, Hematology, Middle Aged, medicine.disease, Hodgkin Disease, Kidney Transplantation, surgical procedures, operative, medicine.anatomical_structure, Treatment Outcome, Oncology, Renal transplant, 030220 oncology & carcinogenesis, Hodgkin lymphoma, business
Abstract

Introduction: Post-transplant lymphoproliferative disease (PTLD) comprises a variety of lymphoid and plasma cell disorders arising in patients with a solid organ transplant. Monomorphic lymphomas represent the most significant part of this wide spectrum, with the overall risk rising with the aggressiveness of lymphoid proliferation in comparison to the general population. The development of Hodgkin lymphoma is very rare in transplant recipients, comprising less than 6% of all monomorphic PTLD, while cases of primary intestinal Hodgkin lymphoma in these circumstances are anecdotal. Case Report: We describe an exceptional case of intestinal Hodgkin lymphoma mimicking an intra-abdominal abscess that developed in a transplant recipient 19 years after kidney transplantation. By presenting this case, we wish to emphasize the importance of suitable diagnostic pathways in transplant recipients experiencing prolonged fever episodes or masses of unknown origin, thus raising the awareness of possible PTLD development in such patients. Conclusion: The lack of information about transplant recipients with Hodgkin PTLD regarding the site of involvement and type of treatment suggests the necessity of conducting larger international studies aimed at providing further insight into this particular group of patients.

Published
2016

40. The Typhoid Toxin Promotes Host Survival and the Establishment of a Persistent Asymptomatic Infection

Author

Del Bel Belluz, L. Guidi, R. Pateras, I.S. Levi, L. Mihaljevic, B. Rouf, S.F. Wrande, M. Candela, M. Turroni, S. Nastasi, C. Consolandi, C. Peano, C. Tebaldi, T. Viero, G. Gorgoulis, V.G. Krejsgaard, T. Rhen, M. Frisan, T.

Abstract

Bacterial genotoxins, produced by several Gram-negative bacteria, induce DNA damage in the target cells. While the responses induced in the host cells have been extensively studied in vitro, the role of these effectors during the course of infection remains poorly characterized. To address this issue, we assessed the effects of the Salmonella enterica genotoxin, known as typhoid toxin, in in vivo models of murine infection. Immunocompetent mice were infected with isogenic S. enterica, serovar Typhimurium (S. Typhimurium) strains, encoding either a functional or an inactive typhoid toxin. The presence of the genotoxic subunit was detected 10 days post-infection in the liver of infected mice. Unexpectedly, its expression promoted the survival of the host, and was associated with a significant reduction of severe enteritis in the early phases of infection. Immunohistochemical and transcriptomic analysis confirmed the toxin-mediated suppression of the intestinal inflammatory response. The presence of a functional typhoid toxin further induced an increased frequency of asymptomatic carriers. Our data indicate that the typhoid toxin DNA damaging activity increases host survival and favours long-term colonization, highlighting a complex cross-talk between infection, DNA damage response and host immune response. These findings may contribute to understand why such effectors have been evolutionary conserved and horizontally transferred among Gram-negative bacteria. © 2016 Del Bel Belluz et al.

Published
2016

43. Achievement of complete remission after autologous stem cell transplantation is strongly corelated with improved survival of patients with Hodgkin lymphoma

Author

Todorovic Balint, M., primary, Jelicic, J., additional, Balint, B., additional, Bila, J., additional, Antic, D., additional, Vujic, D., additional, Kraguljac Kurtovic, N., additional, Sefer, D., additional, Andjelic, B., additional, Smiljanic, M., additional, Djurasinovic, V., additional, Sretenovic, A., additional, Vukovic, V., additional, and Mihaljevic, B., additional

Published
2017
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46. P-051: Thrombosis lymphoma score performance in female population

Author

Antic, D., primary, Milic, N., additional, Nikolovski, S., additional, Todorovic, M., additional, Bila, J., additional, Djurdjevic, P., additional, Andjelic, B., additional, Djurasinovic, V., additional, Sretenovic, A., additional, Vukovic, V., additional, Jelicic, J., additional, and Mihaljevic, B., additional

Published
2017
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49. ABO BLOOD GROUP TYPE AND RISK OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH LYMPHOMA.

Author

Antic, D., Otasevic, V., Ivanovic, J., Vukovic, V., Sarac, S., and Mihaljevic, B.

Subjects
ABO blood group system, THROMBOEMBOLISM, LYMPHOMAS, BLOOD groups
Abstract

A blood type was the most common in our group of patients (41.6%), followed by O blood type (33.3%), B blood type (15.8%) and AB blood type (9.3%), respectively. Non-O blood type lymphoma patients with VTE had significantly more often developed VTE prior to the treatment initiation in comparison with O blood type lymphoma patients with VTE (2.5% vs. 1%, I p i = 0.04), whereas VTE in O blood type lymphoma patients was significantly more often after the initiation of hematological treatment in comparison with VTE in non-O blood type patients (3.8% vs. 3%, I p i = 0.04). VTE was diagnosed before the specific hematological treatment initiation in 46.8% of lymphoma patients, whilst 53.2% of lymphoma patients have been diagnosed with VTE after the hematological treatment commencement. [Extracted from the article]

Published
2023
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50. Enhanced International Prognostic Index (NCCN-IPI), Charlson Comorbidity Index and absolute lymphocyte count as predictors for survival of elderly patients with diffuse large B cell lymphoma treated by immunochemotherapy

Author

JELICIC, J., primary, TODOROVIC BALINT, M., additional, ANTIC, D., additional, SRETENOVIC, A., additional, BALINT, B., additional, PERUNICIC JOVANOVIC, M., additional, ANDJELIC, B., additional, VUKOVIC, V., additional, DJURASINOVIC, V., additional, BILA, J., additional, PAVLOVIC, M., additional, SMILJANIC, M., additional, and MIHALJEVIC, B., additional

Published
2015
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