418 results on '"Midrio, P."'
Search Results
2. Congenital lung malformations: a nationwide survey on management aspects by the Italian Society of Pediatric Surgery
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Pio, Luca, Gentilino, Valerio, Macchini, Francesco, Scarpa, Alberto Attilio, Lo Piccolo, Roberto, Conforti, Andrea, Ratta, Alberto, Guanà, Riccardo, Molinaro, Francesco, Costanzo, Sara, Riccipetitoni, Giovanna, Lisi, Gabriele, Midrio, Paola, Tocchioni, Francesca, Cobellis, Giovannii, Volpe, Andrea, Zolpi, Elisa, Morandi, Anna, Ciardini, Enrico, Vella, Claudio, Grella, Maria Giovanna, Sergio, Maria, Guida, Edoardo, Nanni, Lorenzo, Ceccanti, Silvia, Di Benedetto, Vincenzo, Cheli, Maurizio, Garzi, Alfredo, Nobili, Maria, Gabriele, Valeria, Boroni, Giovanni, Incerti, Filippo, Zampieri, Nicola, Cacciaguerra, Sebastiano, Ceccarelli, Pier Luca, Escolino, Maria, Briganti, Vito, Gori, Davide, Esposito, Ciro, Gamba, Piergiorgio, Gennari, Fabrizio, Inserra, Alessandro, Dall’Igna, Patrizia, Romeo, Carmelo, Bagolan, Pietro, Bleve, Cosimo, Chiarenza, Fabio, Morini, Francesco, Pelizzo, Gloria, and Torre, Michele
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- 2024
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3. Incidental finding of thyroglossal duct cyst in a neonate during endotracheal intubation: a case report
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Emanuele Trovalusci, Carlo Pizzolon, Silvia Tesser, Stefano Doratiotto, Dalia Gobbi, and Paola Midrio
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Thyroglossal duct cyst ,Sistrunk ,Neonate ,Midline neck mass ,Pediatrics ,RJ1-570 - Abstract
Abstract Background Thyroglossal Duct Cyst (TDC) is a common lesion of the midline neck, originating from an incomplete involution of the thyroglossal duct. It is typically observed in pre-scholar patients and surgery is the treatment of choice to prevent infections. Here reported a case of incidental diagnosis in a newborn patient. Case presentation a 3-week-old male baby was admitted to our hospital for weight loss and projectile vomits after breastfeeding. After a diagnosis of hypertrophic pyloric stenosis, the baby underwent pyloromyotomy. During the endotracheal tube placement, the anesthetist noticed the presence of a midline neck mass. The suspect of TDC was confirmed by an intraoperative ultrasound, so, despite the age of the patient, we proceeded with the excision of the lesion according to Sistrunk’s procedure to avoid future complications and anesthesia. Conclusions even if TDC is a common lesion of pediatric patients, anecdotical neonatal cases were described in the literature, all of them symptomatic. An accurate physical examination and ultrasound are essential diagnostic tools to distinguish TDC from other middle neck lesions, particularly ectopic thyroidal tissue. Sistrunk’s procedure is the most effective surgical approach. When diagnosis is made in a newborn, we suggest postponing surgery, unless the baby requires general anesthesia for other surgical procedures, such as in our case.
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- 2024
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4. Influence of Diet on Bowel Function and Abdominal Symptoms in Children and Adolescents with Hirschsprung Disease—A Multinational Patient-Reported Outcome Survey
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Judith Lindert, Hannah Day, Marta de Andres Crespo, Eva Amerstorfer, Sabine Alexander, Manouk Backes, Carlotta de Filippo, Andrzej Golebiewski, Paola Midrio, Mazeena Mohideen, Anna Modrzyk, Anette Lemli, Roxana Rassouli-Kirchmeier, Marijke Pfaff-Jongman, Karolina Staszkiewicz, Lovisa Telborn, Pernilla Stenström, Karolin Holström, Martina Kohl, Joe Curry, Stavros Loukogeorgakis, and Joseph R Davidson
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Hirschsprung disease ,nutrition ,food items ,probiotic use ,patient-reported outcome of Hirschsprung disease ,bowel functions related to Hirschsprung ,Pediatrics ,RJ1-570 - Abstract
Introduction: This study aimed to understand the influence of diet and nutrition items on gastrointestinal symptoms in patients with Hirschsprung Disease (HD). Method: An online questionnaire was created to obtain patient-reported outcomes using the multinational Holistic Care in Hirschsprung Disease Network. This was distributed in Dutch, English, German, Italian, Polish, and Swedish via patient associations. Information on demographics, the extension of disease, current diet, and the influence of food ingredients on bowel function were obtained. Results: In total, 563 questionnaires were answered by parents or patients themselves. The length of the aganglionic segment was short in 33%, long in 45%, total colonic aganglionosis (TCA) in 11%, and involved the small intestine in 10%. Overall, 90% reported following a mixed diet, and 31% reported taking probiotics, with twice as many patients taking probiotics in the TCA group compared to standard HD. Mealtimes and behaviours around eating were affected by 61%, while 77% had established food items that worsened symptoms, and of these, 80% stated that they had worked these items out themselves. A high-fibre diet was followed by 24% and 18% a low-fibre diet. Symptoms were reported, particularly from dairy in 30%, fruits in 39%, pulses in 54%, and sugar in 48%. Conclusions: This first multinational survey on diet and bowel function in HD reports an association between certain dietary items with gastrointestinal symptoms. This study can support an improved understanding of the interaction between food items and bowel function in children with HD. We suggest a multidisciplinary approach to balance dietary exclusions and support adequate growth, preventing nutrition deficiencies and enhancing quality of life.
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- 2024
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5. Congenital Pulmonary Airway Malformation in Preterm Infants: A Case Report and Review of the Literature
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Alessia Bertolino, Silvia Bertolo, Paola Lago, and Paola Midrio
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congenital lung malformation ,CPAM ,CCAM ,prematurity ,very low birth weight ,Science - Abstract
Congenital pulmonary airway malformations (CPAMs) represent a well-known cluster of rare lung malformations affecting 1 in 2500 live births. The natural history of many CPAMs is to increase their size in the second trimester, reach a plateau, and, in about 50% of cases, regress and to become barely detectable during the third trimester. Little is known about cases of affected neonates born prematurely: only six cases are described in the literature, recording different conduct and outcomes. Herein, we report the case of a very low birth weight infant born at GW 28 without antenatal findings and presenting at birth with severe respiratory distress, requiring ventilation. Chest X-rays and a CT scan showed the presence of a solid mass in the left lung. An initial conservative approach was adopted as the baby gained respiratory stability within the first days of life. Routine ultrasound (US) showed a progressive reduction of the lesion, mimicking the process of involution that CPAM can exhibit during late gestation. The rarity of the condition does not allow the formulation of any suggestions regarding one type of management over the other. An initial conservative approach seems to be appropriate with regards to the outcome and possible intra- and post-operative complications.
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- 2024
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6. Rectal atresia and rectal stenosis: the ARM-Net Consortium experience
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de Beaufort, Cunera M. C., Gorter, Ramon R., Iacobelli, Barbara D., Midrio, Paola, Sloots, Cornelius E. J., Samuk, Inbal, van Rooij, Iris A. L. M., and Lisi, Gabriele
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- 2023
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7. Optical Pre-Emphasis by Cascaded Graphene Electro Absorption Modulators
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Sorianello, V., Contestabile, G., Midrio, M., Pantouvaki, M., Asselbergs, I., Van Campenhout, J., Huyghebaerts, C., and Romagnoli, M.
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Physics - Applied Physics ,Electrical Engineering and Systems Science - Signal Processing - Abstract
A simple optical circuit made by a cascade of two graphene-on-silicon electro absorption modulators (EAMs) of different length is used for the optical pre-emphasis of 10 Gb/s non-return-to-zero (NRZ) signals by delay-inverse-weight compensation. Transmission up to 100 km on single mode fiber (SMF) without dispersion compensation is reported, showing also the large performance advantage (6 dB in back-to back and around 5 dB in transmission) in respect of the conventional single EAM transmitter configuration.
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- 2020
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8. Developing the next generation of renewable energy technologies: an overview of low-TRL EU-funded research projects [version 2; peer review: 1 approved, 3 approved with reservations]
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Davide Mencarelli, Philip Schulz, Michele Midrio, Luca Pierantoni, Ignacio Gurruchaga, William Leithead, Jasper Vermaut, Robert Haberl, Michael Kauffeld, Laura María Pérez Caballero, Axel Gottschalk, Fernanda Neira D'Angelo, Daniel Carbonell, Ahmed M. Salem, Arnaud Bruch, Mihaela Dudita-Kauffeld, Luca Pasquini, Eleonora Alamaro, Anastasia Grozdanova, Paola Ceroni, Roman Tschentscher, Bart Vermang, and Stefania Privitera
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renewable energy ,innovative technologies ,research and development ,net-zero greenhouse gas emissions ,eng ,Science ,Social Sciences - Abstract
A cluster of eleven research and innovation projects, funded under the same call of the EU’s H2020 programme, are developing breakthrough and game-changing renewable energy technologies that will form the backbone of the energy system by 2030 and 2050 are, at present, at an early stage of development. These projects have joined forces at a collaborative workshop, entitled ‘Low-TRL Renewable Energy Technologies’, at the 10th Sustainable Places Conference (SP2022), to share their insights, present their projects’ progress and achievements to date, and expose their approach for exploitation and market uptake of their solutions.
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- 2023
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9. First trimester lower abdominal cysts as early predictor of anorectal malformations
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Erculiani, Marta, Trovalusci, Emanuele, Zanatta, Cinzia, De Lorenzis, Maria Sonia, Filippi, Elisa, Bracalente, Gabriella, and Midrio, Paola
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- 2022
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10. Talking about sexuality with your own child. The perspective of the parents of children born with arm
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Eleuteri, S., Aminoff, D., Midrio, P., Leva, E., Morandi, A., Spinoni, M., and Grano, C.
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- 2022
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11. Diagnosis and Management of Congenital H-Type Tracheoesophageal Fistula: Results of a National Survey
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Cecilia Morchio, Alba Ganarin, Andrea Conforti, Ernesto Leva, Giovanni Gaglione, Gaia Brenco, Elisa Zambaiti, Salvatore Fabio Chiarenza, Tamara Caldaro, Maurizio Cheli, Giovanni Boroni, Elena Sofia Marcandella, Giovanna Riccipetitoni, Sebastiano Cacciaguerra, Vincenzo Di Benedetto, Valerio Gentilino, Gabriele Lisi, Francesco Morini, and Paola Midrio
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congenital tracheoesophageal fistula ,h-type esophageal atresia ,type E esophageal atresia ,Pediatrics ,RJ1-570 - Abstract
Background: Congenital h-type tracheoesophageal fistula (H-TEF) without esophageal atresia (EA) represents about 4% of congenital esophageal anomalies. The diagnosis is challenging, and surgery is considered curative. The aim was to report a national survey on the diagnosis, management, and outcome of patients with congenital H-TEF. Methods: Following approval of the Italian Society of Pediatric Surgery, a survey was sent to all Pediatric Surgery Units to retrospectively collect H-TEF treated in the period 2010–2022. Descriptive analysis was performed, and results are given as prevalence, mean ± standard deviation (SD), or median and interquartile range (IQR). Results: The survey was sent to 65 units. Seventeen responded with one or more cases; 78 patients were diagnosed with H-TEF during the study period. Associated malformations were present in 43%, mostly cardiac (31%). The most frequent symptoms were cough (36%), bronchopneumonia (24%), and dysphagia (19%). H-TEF was detected by tracheobronchoscopy (90%), and/or upper GI (58%), and/or esophagoscopy (32%). The median age at diagnosis was 23 days (1 day–18 years). The most common approach was cervicotomy (76%), followed by thoracoscopy (14%) and thoracotomy (9%). The fistula underwent ligation and section of the fistula in 90% of the patients and clip closure and section in 9%. In one patient, the fistula was cauterized endoscopically. H-TEF preoperative cannulation was performed in 68% of cases, and a drain was placed in 26%. One month after surgery, 13% of the patients had mild persisting symptoms, mainly hypophonia. Recurrence occurred in 5%, and a second recurrence occurred in 1%. Conclusions: H-TEF prevalence was six cases/year, consistent with the expected rate of five cases/year in our country. The diagnosis was challenging, sometimes delayed, and, in most patients, required multiple examinations. Fistula ligation and section through cervicotomy were the most frequent treatment. Long-term outcomes are good, and recurrence is a rare event.
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- 2024
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12. Sub-Gigahertz Path Loss Measurement Campaign in Marine Environment: A Case Study
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Marco De Piante, Michele Midrio, Roberto Rinaldo, Ivan Scagnetto, Ruben Specogna, and Francesco Trevisan
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data communication ,marine environment ,path loss ,sub-gigahertz bands ,Chemical technology ,TP1-1185 - Abstract
This paper focuses on the characterization of radio propagation, and data communication in a marine environment. More specifically, we consider signal propagation when three different sub-gigahertz industrial, scientific, and medical (ISM) bands, i.e., 169 MHz, 434 MHz, and 868 MHz, are used. The main focus of the paper is to evaluate the path loss (PL), i.e., the power loss that a propagation radio wave would experience when communication occurs between a sail boat and a buoy. We describe the measurement results obtained performing three different radio power measurement campaigns, at the three different aforementioned ISM sub-gigahertz bands. We also want to correlate the radio propagation quality with the weather conditions present in the measurement areas. The obtained results show that higher distances are achieved by transmitting at lower frequencies, i.e., 169 MHz, and, on average, the propagation is directly dependent from the dew point index.
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- 2024
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13. Graphene-Based Integrated Photonics For Next-Generation Datacom And Telecom
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Romagnoli, M., Sorianello, V., Midrio, M., Koppens, F. H. L., Huyghebaert, C., Neumaier, D., Galli, P., Templ, W., D'Errico, A., and Ferrari, A. C.
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Physics - Applied Physics - Abstract
Graphene is an ideal material for optoelectronic applications. Its photonic properties give several advantages and complementarities over Si photonics. For example, graphene enables both electro-absorption and electro-refraction modulation with an electro-optical index change exceeding 10$^{-3}$. It can be used for optical add-drop multiplexing with voltage control, eliminating the current dissipation used for the thermal detuning of microresonators, and for thermoelectric-based ultrafast optical detectors that generate a voltage without transimpedance amplifiers. Here, we present our vision for grapheme-based integrated photonics. We review graphene-based transceivers and compare them with existing technologies. Strategies for improving power consumption, manufacturability and wafer-scale integration are addressed. We outline a roadmap of the technological requirements to meet the demands of the datacom and telecom markets. We show that graphene based integrated photonics could enable ultrahigh spatial bandwidth density , low power consumption for board connectivity and connectivity between data centres, access networks and metropolitan, core, regional and long-haul optical communications.
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- 2019
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14. Waveguide-integrated, plasmonic enhanced graphene photodetectors
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Muench, J. E., Ruocco, A., Giambra, M. A., Miseikis, V., Zhang, D., Wang, J., Watson, H. F. Y., Park, G. C., Akhavan, S., Sorianello, V., Midrio, M., Tomadin, A., Coletti, C., Romagnoli, M., Ferrari, A. C., and Goykhman, I.
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Physics - Applied Physics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
We present a micrometer scale, on-chip integrated, plasmonic enhanced graphene photodetector (GPD) for telecom wavelengths operating at zero dark current. The GPD is designed and optimized to directly generate a photovoltage and has an external responsivity~12.2V/W with a 3dB bandwidth~42GHz. We utilize Au split-gates with a$\sim$100nm gap to electrostatically create a p-n-junction and simultaneously guide a surface plasmon polariton gap-mode. This increases light-graphene interaction and optical absorption and results in an increased electronic temperature and steeper temperature gradient across the GPD channel. This paves the way to compact, on-chip integrated, power-efficient graphene based photodetectors for receivers in tele and datacom modules
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- 2019
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15. Resolution of Fetal hydrops-not a favorable outcome in congenital pulmonary malformation type 1: A case report with review of literature
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Dalia Gobbi, Elisa Filippi, Gabriella Bracalente, Francesca Baciorri, and Paola Midrio
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congenital cystic adenomatoid malformation of lung ,counseling ,fetal hydrops ,prenatal diagnosis ,Pediatrics ,RJ1-570 - Abstract
Background: Congenital pulmonary airway malformations (CPAMs) comprise a spectrum of anatomical anomalies of the lungs and respiratory tree. The natural history of prenatally diagnosed CPAM varies from in utero resolution to progression to hydrops and intrauterine death. The majority of fetuses (90%) have a good outcome. However, in a minority (10%), the mass may grow so large that it is associated with complications and becomes life-threatening to the fetus. Clinical Description: Prenatal diagnosis of giant left CPAM type 1 was made at 24 weeks of gestation in a 29-year-old primigravida woman. The lesion consisted of multiple large cysts with a CPAM volume ratio of 4.7. Since the diagnosis, the mass was associated with nonimmune fetal hydrops and polyhydramnios which got worse throughout the following 4 weeks of gestation. Doppler studies remained normal until term. Management: The family received prenatal counseling. Parents refused termination of pregnancy and any other invasive or pharmacological therapy in light of the bad prognosis. The pregnancy was strictly monitored using standard fetal lung parameters. By 31 weeks' gestation, hydrops spontaneously improved to resolution but without any change in the size of the cysts. A baby girl was delivered at term, with birth asphyxia, who, despite all efforts by a multidisciplinary team, could not be revived. Autopsy and histopathological findings were compatible with type 1 CPAM. Conclusion: Hydrops is a well-known complication in fetuses with congenital cystic adenomatoid malformation. The present case reminds the possibility of its spontaneous resolution during pregnancy, even though the cyst size remains unaltered. The eventual neonatal survival depends not on the presence of hydrops but on the cyst volume and underlying lung hypoplasia.
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- 2023
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16. The use of biological membranes for correction of congenital malformations
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Marchetto, C, Sgrò, A, Gamba, P, Trojan, D, Pagliara, C, and Midrio, P
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- 2022
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17. Graphene Phase Modulator
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Sorianello, V., Midrio, M., Contestabile, G., Asselberg, I., Van Campenhout, J., Huyghebaerts, C., Goykhman, I., Ott, A. K., Ferrari, A. C., and Romagnoli, M.
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Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
We demonstrate a 10Gb/s Graphene Phase Modulator (GPM) integrated in a Mach-Zehnder interferometer configuration. This is a compact device, with a phase-shifter length of only 300$\mu$m, and 35dB extinction ratio. The GPM has modulation efficiency of 0.28Vcm, one order of magnitude higher compared to state-of-the-art depletion p-n junction Si phase modulators. Our GPM operates with 2V peak-to-peak driving voltage in a push-pull configuration, and it has been tested in a binary transmission of a non-return-to-zero data stream over 50km single mode fibre. This device is the key building block for graphene-based integrated photonics, enabling compact and energy efficient hybrid Si-graphene modulators for telecom, datacom and other applications
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- 2017
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18. Developing the next generation of renewable energy technologies: an overview of low-TRL EU-funded research projects [version 1; peer review: 1 approved, 3 approved with reservations]
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Davide Mencarelli, Philip Schulz, Michele Midrio, Luca Pierantoni, Ignacio Gurruchaga, William Leithead, Jasper Vermaut, Robert Haberl, Michael Kauffeld, Laura María Pérez Caballero, Axel Gottschalk, Fernanda Neira D'Angelo, Daniel Carbonell, Ahmed M. Salem, Arnaud Bruch, Mihaela Dudita-Kauffeld, Luca Pasquini, Eleonora Alamaro, Anastasia Grozdanova, Paola Ceroni, Roman Tschentscher, Bart Vermang, and Stefania Privitera
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renewable energy ,innovative technologies ,research and development ,net-zero greenhouse gas emissions ,eng ,Science ,Social Sciences - Abstract
A cluster of eleven research and innovation projects, funded under the same call of the EU’s H2020 programme, are developing breakthrough and game-changing renewable energy technologies that will form the backbone of the energy system by 2030 and 2050 are, at present, at an early stage of development. These projects have joined forces at a collaborative workshop, entitled ‘Low-TRL Renewable Energy Technologies’, at the 10th Sustainable Places Conference (SP2022), to share their insights, present their projects’ progress and achievements to date, and expose their approach for exploitation and market uptake of their solutions.
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- 2023
- Full Text
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19. Audio quality level vs. signal-to-interference ratio in isofrequency FM broadcasting
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De Piante, Marco, Boscolo, Stefano, Turco, Emanuele, Gardonio, Paolo, and Midrio, Michele
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- 2021
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20. The Alexis® system for laparoscopic splenectomy in pediatric patients
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Trovalusci, Emanuele, Gasparella, Marco, Pizzato, Cristina, and Midrio, Paola
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- 2021
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21. Gynecological and psycho-sexual aspects of women with history of anorectal malformations
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Bicelli, Noemi, Trovalusci, Emanuele, Zannol, Monica, Gamba, Piergiorgio, Bogana, Gianna, Zanatta, Cinzia, and Midrio, Paola
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- 2021
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22. Fetal Lung Interstitial Tumor (FLIT): Review of The Literature
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Silvia Perin, Ivana Cataldo, Francesca Baciorri, Luisa Santoro, Angelo Paolo Dei Tos, Maria Guido, and Paola Midrio
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FLIT ,lung tumors ,congenital pulmonary malformations ,respiratory distress ,Pediatrics ,RJ1-570 - Abstract
Fetal lung interstitial tumor (FLIT) is an extremely rare pediatric lung tumor that shares radiological features with congenital pulmonary malformations (cPAM) and other lung neoplasms. A review of the literature, together with the first European case, are herein reported. A systematic and manual search of the literature using the keyword “fetal lung interstitial tumor” was conducted on PUBMED, Scopus, and SCIE (Web of Science). Following the PRISMA guidelines, 12 articles were retrieved which describe a total of 21 cases of FLIT, and a new European case is presented. A prenatal diagnosis was reported in only 3 out of 22 (13%) cases. The mean age at surgery was 31 days of life (1–150); a lobectomy was performed in most of the cases. No complications or recurrence of disease were reported at a mean follow-up of 49 months. FLIT is rarely diagnosed during pregnancy, may present at birth with different levels of respiratory distress, and requires prompt surgical resection. Histology and immunohistochemistry allow for the differentiation of FLIT from cPAM and other lung tumors with poor prognosis, such as pleuropulmonary blastoma, congenital peri-bronchial myofibroblastic tumor, inflammatory myofibroblastic tumor, and congenital or infantile fibrosarcoma.
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- 2023
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23. The European Anorectal Malformation Network (ARM-Net) patient registry: 10-year review of clinical and surgical characteristics
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Hageman, I.C., Midrio, P., Steeg, H.J.J. van der, Jenetzky, E., Iacobelli, B.D., Morandi, A., Sloots, C. E. J., Schmiedeke, E., Broens, P.M., Leon, F. Fascetti, Çavuşoğlu, Y.H., Gorter, R.R., Trajanovska, M., King, S.K., Aminoff, D., Schwarzer, N., Marcelis, C.L.M., Verhaak, C.M., Haanen, M., Blaauw, I. de, Rooij, I.A.L.M. van, Hageman, I.C., Midrio, P., Steeg, H.J.J. van der, Jenetzky, E., Iacobelli, B.D., Morandi, A., Sloots, C. E. J., Schmiedeke, E., Broens, P.M., Leon, F. Fascetti, Çavuşoğlu, Y.H., Gorter, R.R., Trajanovska, M., King, S.K., Aminoff, D., Schwarzer, N., Marcelis, C.L.M., Verhaak, C.M., Haanen, M., Blaauw, I. de, and Rooij, I.A.L.M. van
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Contains fulltext : 305111.pdf (Publisher’s version ) (Open Access)
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- 2024
24. Congenital pouch colon: Case series and review of evidences for resection
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Miriam Duci, Francesco Fascetti-Leon, Enrico La Pergola, Paola Midrio, and Piergiorgio Gamba
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anorectal malformation ,augmentation bladder capacity ,congenital pouch colon ,vaginal reconstruction ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
Background: Congenital pouch colon (CPC) is a rare variant of anorectal malformations (ARM) with its highest reported incidence in India. We aimed to describe five patients affected by CPC, in which the tissue from the terminal dilated colon has been successfully used and to discuss our results on the light of an extended revision of the literature. Materials and Methods: The clinical details of five cases treated for CPC in two Italian Centers were retrospectively reviewed assessing the fate of the terminal dilated colon. Results: In all cases, the tissue from dilated colon has been used. The double vascular system of the dilated pouch allowed increasing bladder capacity (case 4), reconstruction of the vagina (case 3, 5), and lengthening of the colon (case 1, 2, 5). In our series, 3/5 have a good bowel control with daily bowel management after ARM correction. In literature, there are not differences in terms of dependence from bowel management in patients with pouch resected and in patients with pouch saved (P = 0.16). Conclusions: We acknowledge that the analysis of the available literature is limited by the absence of studies with high level of evidence and the removal or the preservation of the abnormal colon tissue seems to follow the surgeon preferences.
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- 2021
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25. Bedside surgery in the newborn infants: survey of the Italian society of pediatric surgery
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Gloria Pelizzo, Pietro Bagolan, Francesco Morini, Mariagrazia Aceti, Daniele Alberti, Mario Andermarcher, Luigi Avolio, Fabio Bartoli, Vito Briganti, Sebastiano Cacciaguerra, Francesco S. Camoglio, Pierluca Ceccarelli, Maurizio Cheli, Fabio Chiarenza, Enrico Ciardini, Marcello Cimador, Ennio Clemente, Denis A. Cozzi, Luigi Dall’ Oglio, Ugo De Luca, Carmine Del Rossi, Ciro Esposito, Diego Falchetti, Silvana Federici, Piergiorgio Gamba, Valerio Gentilino, Girolamo Mattioli, Ascanio Martino, Mario Messina, Bruno Noccioli, Alessandro Inserra, Pierluigi Lelli Chiesa, Ernesto Leva, Francesco Licciardi, Paola Midrio, Maria Nobili, Alfonso Papparella, Guglielmo Paradies, Giuseppe Piazza, Alessio Pini Prato, Fabio Rossi, Giovanna Riccipetitoni, Carmelo Romeo, Domenico Salerno, Alessandro Settimi, Jurgen Schleef, Mario Milazzo, Valeria Calcaterra, and Mario Lima
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Neonatal intensive care unit ,Bedside surgery ,Operative room ,Intrahospital transport ,Critically ill neonates ,Pediatrics ,RJ1-570 - Abstract
Abstract Introduction This is the report of the first official survey from the Italian Society of Pediatric Surgery (ISPS) to appraise the distribution and organization of bedside surgery in the neonatal intensive care units (NICU) in Italy. Methods A questionnaire requesting general data, staff data and workload data of the centers was developed and sent by means of an online cloud-based software instrument to all Italian pediatric surgery Units. Results The survey was answered by 34 (65%) out of 52 centers. NICU bedside surgery is reported in 81.8% of the pediatric surgery centers. A lower prevalence of bedside surgical practice in the NICU was reported for Southern Italy and the islands than for Northern Italy and Central Italy (Southern
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- 2020
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26. Polarization Independent Unidirectional Scattering With Turnstile Nanoantennas
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Davide Rocco, Michele Midrio, and Costantino De Angelis
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Optical resonator ,metamaterials ,Applied optics. Photonics ,TA1501-1820 ,Optics. Light ,QC350-467 - Abstract
We study the scattering behavior of a dielectric cross-dipole nanoantenna in the near-infrared spectral range when it is excited by a circular polarized plane wave. We theoretically demonstrate, for optimized geometrical parameters of the proposed turnstile structure, the possibility to simultaneously obtain a unidirectional scattering and a specific circular polarization of the scattered field. Our results open new functionalities for metamaterials and optical nanoantennas.
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- 2020
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27. Iatrogenic Neonatal Esophageal Perforation: A European Multicentre Review on Management and Outcomes
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Eva Sorensen, Connie Yu, Shu-Ling Chuang, Paola Midrio, Leopoldo Martinez, Mathew Nash, Ingo Jester, and Amulya K. Saxena
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esophageal perforation ,neonates ,nasogastric tube ,management ,outcomes ,Pediatrics ,RJ1-570 - Abstract
Background: The aim of this multicenter retrospective study and literature review was to review management and outcomes of neonatal esophageal perforation (NEP). Methods: Protocol data were collected from four European Centers on gestational age, factors surrounding feeding tube insertion, management and outcomes. Results: The 5-year study period (2014–2018) identified eight neonates with median gestational age of 26 + 4 weeks (23 + 4–39) and median birth weight 636 g (511–3500). All patients had NEP from enterogastric tube insertions, with the perforation occurring at median 1st day of life (range 0–25). Seven/eight patients were ventilated (two/seven-high frequency oscillation). NEP became apparent on first tube placement (n = 1), first change (n = 5), and after multiple changes (n = 2). Site of perforation was known in six (distal n = 3, proximal n = 2 and middle n = 1). Diagnosis was established by respiratory distress (n = 4), respiratory distress and sepsis (n = 2) and post-insertion chest X-ray (n = 2). Management in all patients included antibiotics and parenteral nutrition with two/eight receiving steroids and ranitidine, one/eight steroids only and one/eight ranitidine only. One neonate had a gastrostomy inserted, while in another an enterogastric tube was orally successfully re-inserted. Two neonates developed pleural effusion and/or mediastinal abscess requiring chest tube. Three neonates had significant morbidities (related to prematurity) and there was one death 10 days post-perforation (related to prematurity complications). Conclusions: NEP during NGT insertion is rare even in premature infants after evaluating data from four tertiary centers and reviewing the literature. In this small cohort, conservative management seems to be safe. A larger sample size will be necessary to answer questions on efficacy of antibiotics, antacids and NGT re-insertion time frame in NEP.
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- 2023
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28. Graphene Based Optical Phase Modulation
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Midrio, Michele, Galli, Paola, Romagnoli, Marco, Kimerling, Lionel C., and Michel, Jurgen
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Physics - Optics - Abstract
In this paper we report phase modulation obtained by inducing a capacitive charge on graphene layers embedded in the core of a waveguide. There is a biasing regime in which graphene absorption is negligible but large index variations can be achieved with a voltage-length product as small as $V_\pi\,L_\pi \simeq 0.04 $\,V\,cm . Examples of phase induced changes are computed for straight waveguides and for microring resonators showing the possibility to implement several optoelectronic functionalities as modulators, tunable filters, and switches., Comment: Review needed due to an error in an expression
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- 2013
29. Transanal irrigation (TAI) in the paediatric population: Literature review and consensus of an Italian multicentre working group
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Enrica Caponcelli, Milena Meroni, Giulia Brisighelli, Claudia Rendeli, Emanuele Ausili, Piergiorgio Gamba, Antonio Marte, Barbara Daniela Iacobelli, Laura Lombardi, Ernesto Leva, and Paola Midrio
- Subjects
Transanal irrigation ,constipation ,incontinence ,bowel management ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
Constipation and fecal incontinence in pediatric patients are conditions due to either functional or organic bowel dysfunction and may represent a challenging situation both for parents, pediatricians, and pediatric surgeons. Different treatments have been proposed throughout the past decades with partial and alternant results and, among all proposed techniques, in the adult population the Transanal Irrigation (TAI) has become popular. However, little is known about its efficacy in children. Therefore, a group of Italian pediatric surgeons from different centers, all experts in bowel management, performed a literature review and discussed the best-practice for the use of TAI in the pediatric population. This article suggests some tips, such as the careful patients’ selection, a structured training with expert in pediatric colorectal diseases, and a continuous follow-up, that are considered crucial for the full success of treatment.
- Published
- 2021
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30. Full three dimensional inverse design of dielectric slab based scattering optical elements devices
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Hakansson, Andreas, Boscolo, Stefano, and Midrio, Michele
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Condensed Matter - Other Condensed Matter - Abstract
Inverse design through optimization of dielectric photonic devices is a very powerful tool. However so far the direct solver used in the design process is almost always restricted to solve Maxwell's equation in two dimensions (2D). Here we will show that by using a specific three dimensional (3D) electromagnetic field-solver we can implement a full 3D inverse design tool for Silicon On Insulator (SOI) slab based photonic structures which can be run on a normal desktop computer., Comment: 9 pages, 3 figtures (2 in color)
- Published
- 2008
31. Clinical Differentiation between a Normal Anus, Anterior Anus, Congenital Anal Stenosis, and Perineal Fistula: Definitions and Consequences—The ARM-Net Consortium Consensus
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Eva E. Amerstorfer, Eberhard Schmiedeke, Inbal Samuk, Cornelius E. J. Sloots, Iris A. L. M. van Rooij, Ekkehart Jenetzky, Paola Midrio, and ARM-Net Consortium
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anorectal malformation ,anterior anus ,anal position index ,perineal fistula ,anal stenosis ,ARM-Net Consortium ,Pediatrics ,RJ1-570 - Abstract
In the past, an anteriorly located anus was often misdiagnosed and treated as an anorectal malformation (ARM) with a perineal fistula (PF). The paper aims to define the criteria for a normal anus, an anterior anus (AA) as an anatomic variant, and milder types of ARM such as congenital anal stenosis (CAS) and PF. An extensive literature search was performed by a working group of the ARM-Net Consortium concerning the subject “Normal Anus, AA, and mild ARM”. A consensus on definitions, clinical characteristics, diagnostic management, and treatment modalities was established, and a diagnostic algorithm was proposed. The algorithm enables pediatricians, midwives, gynecologists, and surgeons to make a timely correct diagnosis of any abnormally looking anus and initiate further management if needed. Thus, the routine physical inspection of a newborn should include the inspection of the anus and define its position, relation to the external sphincter, and caliber. A correct diagnosis and use of the presented terminology will avoid misclassifications and allow the initiation of correct management. This will provide a reliable comparison of different therapeutic management and outcomes of these patient cohorts in the future.
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- 2022
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32. Podcast. Incidental Finding of Thyroglossal Duct Cyst in a Neonate During Endotracheal Intubation: A Case Report.
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Trovalusci, Emanuele, Pizzolon, Carlo, Tesser, Silvia, Doratiotto, Stefano, Gobbi, Dalia, and Midrio, Paola
- Published
- 2024
33. Application of a non-pharmacological technique in addition to the pharmacological protocol for the management of children’s preoperative anxiety: A 10 years’ experience
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Francesca Scarano, Alessandra Dalla Corte, Roberto Michielon, Alessandro Gava, and Paola Midrio
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Preoperative anxiety ,non-pharmacological techniques ,day-surgery ,coping strategies ,children ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
The aim of the study was to investigate how Non- Pharmacological Techniques (NPT), in addition to standard pharmacological techniques, can help to manage and reduce the preoperative anxiety of children waiting for Day Surgery procedures (DS). Isola Serena activity started in 2008 to manage the preoperative time of children waiting for surgery in the playing room. The latter is run by a pedagogist. NPT includes use of games and toys, readings and drawings. A descriptive and comparative study was conducted on 50 children, aged 4 to 12 years, randomly assigned to Isola Serena group ISG and control group CG. All children received standard pharmacological techniques, while those of the ISG also received the NPT. The evaluation of the preoperative anxiety level (modified Yale Preoperative Anxiety Scale) and parent’s coping style (Coping Inventory for Stressful Situation) compared the two groups. The ISG showed a significantly lower level of preoperative anxiety than the CG. Parents’ coping style was not related to the preoperative anxiety. The activity performed in the Isola Serena Project resulted to be effective for the reduction of preoperative anxiety in children undergoing DS procedures.
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- 2021
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34. Ulcerative Colitis of the Neovagina in a Toddler with Cloaca and Chronic Kidney Disease
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Marta Erculiani, Cinzia Zanatta, Enrico Vidal, Stefano Martelossi, and Paola Midrio
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cloaca ,neovagina ,anorectal malformation ,diagnosis ,ulcerative ,colitis ,Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
The case of a toddler with long-channel cloaca, mild chronic kidney disease (CKD) due to renal dysplasia, and early onset of ulcerative colitis (UC) is herein reported. The patient underwent definitive repair of cloaca, that included vaginal elongation with colon, at 5 months of age and was admitted for episodes of vaginal bleeding at 22 months of age. A vaginoscopy revealed a severe inflammation of the colonic neovagina. As rectal bleeding was also noticed, she underwent a colonscopy that showed the same macroscopic inflammatory picture. Neovaginal and colonic biopsies confirmed UC. The mother turned out to be affected by UC since adolescence. The patient is now on oral therapy with mesalazine and topical steroid and mesalazine in the neovagina. The association between cloaca and inflammatory bowel disease (IBD) is anecdotal, but the family history of IBD should be considered when planning the surgical reconstruction of patients with cloaca. In this patient, the occurrence of UC may require a new neovagina in the future and the concomitance of CKD may complicate the overall management due to the potential nephrotoxicity of drugs used for UC therapy.
- Published
- 2021
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35. Short versus mid-long-term outcome of transanal irrigation in children with spina bifida and anorectal malformations
- Author
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Ausili, Emanuele, Marte, A., Brisighelli, G., Midrio, P., Mosiello, G., La Pergola, E., Lombardi, L., Iacobelli, B. D., Caponcelli, E., Meroni, M., Leva, E., and Rendeli, C.
- Published
- 2018
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36. Inter- and Intraobserver Variation in the Assessment of Preoperative Colostograms in Male Anorectal Malformations: An ARM-Net Consortium Survey
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Paola Midrio, Iris A. L. M. van Rooij, Giulia Brisighelli, Aracelli Garcia, Maria Fanjul, Paul Broens, Barbara D. Iacobelli, Carlos Giné, Gabriele Lisi, Cornelius E. J. Sloots, Francesco Fascetti Leon, Anna Morandi, Herjan van der Steeg, Stefan Giuliani, Sabine Grasshoff-Derr, Martin Lacher, Ivo de Blaauw, and Ekkehart Jenetzky
- Subjects
anorectal malformation ,urinary fistula ,colostogram ,surgery ,ARM-net ,multirater agreement ,Pediatrics ,RJ1-570 - Abstract
Aim: Male patients with anorectal malformations (ARM) are classified according to presence and level of the recto-urinary fistula. This is traditionally established by a preoperative high-pressure distal colostogram that may be variably interpreted by different surgeons. The aim of this study was to evaluate the inter- and intraobserver variation in the assessment by pediatric surgeons of preoperative colostograms with respect to the level of the recto-urinary fistula.Materials and Methods: Sixteen pediatric surgeons from 14 European centers belonging to the ARM-Net Consortium twice scored 130 images of distal colostograms taken in sagittal projection at a median age of 66 days of life (range: 4–1,106 days). Surgeons were asked to classify the fistula in bulbar, prostatic, bladder-neck, no fistula, and “unclear anatomy” example. Their assessments were compared with the intraoperative findings (kappa) for two scoring rounds with an interval of 6 months (intraobserver variation). Agreement among the surgeons' scores (interobserver variation) was also calculated using Krippendorff's alpha. A kappa over 0.75 is considered excellent, between 0.40 and 0.75 fair to good, and below 0.40 poor. Surgeons were asked to score the images in “poor” and “good” quality and to provide their years of experience in ARM treatment.Results: Agreement between the image-based rating of surgeons and the intraoperative findings ranges from 0.06 to 0.45 (mean 0.31). Interobserver variation is higher (Krippendorff's alpha between 0.40 and 0.45). Years of experience in ARM treatment does not seem to influence the scoring. The mean intraobserver variation between the two rounds is 0.64. Overall, the quality of the images is considered poor. Images categorized as having a good quality result in a statistically significant higher kappa (mean: 0.36 and 0.37 in the first and second round, respectively) than in the group of bad-quality images (mean: 0.25 and 0.23, respectively).Conclusions: There is poor agreement among experienced pediatric colorectal surgeons on preoperative colostograms. Techniques and analyses of images need to be improved in order to generate a homogeneous series of patients and make comparison of outcomes reliable.
- Published
- 2020
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37. VY anoplasty for ectropion of anal mucosa in an adult with anorectal malformation
- Author
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Enrico La Pergola, Francesco Fascetti Leon, Franco Bassetto, Paola Midrio, and Piergiorgio Gamba
- Subjects
Pediatrics ,RJ1-570 ,Surgery ,RD1-811 - Abstract
Ectropion of anal mucosa (AME) is a possible complication following anorectal surgery and it is often cause of symptoms such as soiling, pain and bleeding affecting the patients' quality of life. Two-flaps anoplasty has been previously described for the correction of AME. We herein report a case of an adult patient who underwent a successful double V/Y-flaps for mucosal ectropion as consequence of repair of anorectal malformation (ARM).A 25 year-old woman with history of ARM presented with an extensive AME causing bleeding, pain, soiling, and dyspareunia. This condition prevented her from an effective rectal nursing and a satisfactory social life.The patient underwent the resection of ectopic mucosa and the creation of two V-shaped skin flaps to cover the skin gap. A minor dehiscence of one of the flaps was treated conservatively. At two years follow up the patient is symptoms free, has a good quality of life and can perform an effective bowel management.AME is a possible complication after anorectal surgery for ARM and the multiple V-Y plasty is a viable procedure for its treatment. A multidisciplinary approach in these cases is recommended.Level of Evidence V. Keywords: Anorectal malformation, Anoplasty, V-Y flaps, Mucosal ectropion
- Published
- 2019
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38. Comprehensive Analysis of Graphene Geometric Diodes: Role of Geometrical Asymmetry and Electrostatic Effects
- Author
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Truccolo, D., Palestri, P., Esseni, D., Boscolo, S., and Midrio, M.
- Abstract
A self-consistent Monte Carlo/3-D Poisson simulator has been developed to analyze the current asymmetry in graphene geometric diodes. The model couples ballistic transport in the graphene layer with 3-D electrostatics in the graphene and oxide substrate. Results are given in terms of transmission coefficients and currents at the two terminals of the diode. We prove that while the current asymmetry is mainly induced by ballistic transport in the asymmetric structure, the electrostatics plays a relevant role that tends to substantially counterbalance the geometrical effect.
- Published
- 2024
- Full Text
- View/download PDF
39. Lossless Tapers, Gaussian Beams, Free-Space Modes: Standing Waves Versus Through-Flowing Waves
- Author
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Capobianco, A. D., Midrio, M., Someda, C. G., and Curtarolo, S.
- Subjects
Physics - Optics ,Condensed Matter - Materials Science - Abstract
It was noticed in the past that, to avoid physical inconsistencies, in Marcatili's lossless tapers through-flowing waves must be drastically different from standing waves. First, we reconfirm this by means of numerical results based on an extended BPM algorithm. Next, we show that this apparently surprising behavior is a straightforward fallout of Maxwell's equations. Very similar remarks apply to Gaussian beams in a homogeneous medium. As a consequence, Gaussian beams are shown to carry reactive powers, and their active power distributions depart slightly from their standard pictures. Similar conclusions hold for free-space modes expressed in terms of Bessel functions., Comment: 19 pages and 6 figures
- Published
- 1998
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40. Bedside surgery in the newborn infants: survey of the Italian society of pediatric surgery
- Author
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Pelizzo, Gloria, Bagolan, Pietro, Morini, Francesco, Aceti, Mariagrazia, Alberti, Daniele, Andermarcher, Mario, Avolio, Luigi, Bartoli, Fabio, Briganti, Vito, Cacciaguerra, Sebastiano, Camoglio, Francesco S., Ceccarelli, Pierluca, Cheli, Maurizio, Chiarenza, Fabio, Ciardini, Enrico, Cimador, Marcello, Clemente, Ennio, Cozzi, Denis A., Dall’ Oglio, Luigi, De Luca, Ugo, Del Rossi, Carmine, Esposito, Ciro, Falchetti, Diego, Federici, Silvana, Gamba, Piergiorgio, Gentilino, Valerio, Mattioli, Girolamo, Martino, Ascanio, Messina, Mario, Noccioli, Bruno, Inserra, Alessandro, Lelli Chiesa, Pierluigi, Leva, Ernesto, Licciardi, Francesco, Midrio, Paola, Nobili, Maria, Papparella, Alfonso, Paradies, Guglielmo, Piazza, Giuseppe, Pini Prato, Alessio, Rossi, Fabio, Riccipetitoni, Giovanna, Romeo, Carmelo, Salerno, Domenico, Settimi, Alessandro, Schleef, Jurgen, Milazzo, Mario, Calcaterra, Valeria, and Lima, Mario
- Published
- 2020
- Full Text
- View/download PDF
41. Elimination of scan blindness in phased array antennas using a grounded-dielectric EBG material
- Author
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Donzelli, G, Capolino, F, Boscolo, S, and Midrio, M
- Subjects
arrays ,band gap ,dielectric resonators ,electromagnetic bandgap (EBG) materials ,phased arrays ,scan blindness ,Networking & Telecommunications ,Electrical and Electronic Engineering ,Communications Technologies - Abstract
In printed phased arrays, scan blindness occurs when the propagation constant of a Floquet mode coincides with that of a mode supported by the homogeneous substrate, resulting in large input mismatch and in a propagating mode with complex propagation constant. In our study we analyze the possibility to replace a standard homogeneous dielectric substrate with a grounded dielectric EBG substrate to eliminate scan blindness. We present here the main idea for the design, the dispersion diagrams of a dielectric EBG material with metallic patches to show that there are no surface modes (waves guided by the structure with real propagation constant), and the active reflection coefficient and input impedance for various frequencies. Furthermore, at a chosen operating frequency the active reflection coefficient for the phased case indicates that there is no scan blindness effect. © 2007 IEEE.
- Published
- 2007
42. Tethered cord in patients affected by anorectal malformations: a survey from the ARM-Net Consortium
- Author
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Fanjul, María, Samuk, I., Bagolan, P., Leva, E., Sloots, C., Giné, C., Aminoff, D., Midrio, P., Aminoff, Dalia, Bagolan, Piero, De Blaauw, Ivo, Deluggi, Stefan, Fanjul, María, Fascetti Leon, Francesco, García, Araceli, Giné, Carles, Giuliani, Stefano, Grano, Caterina, Grasshoff-Derr, Sabine, Haanen, Michel, Holland-Cunz, Stephan, Jenetzky, Ekkehart, Lacher, Martin, Leva, Ernesto, Lisi, Grabiele, Makedonsky, Igor, Marcelis, Carlos, Midrio, Paola, Miserez, Marc, Ozen, Onur, Percin, Ferda, Reutter, Heiko, Rohleder, Stephan, Samuk, Inbal, Schmiedeke, Eberhard, Schwarzer, Nicole, Sloots, Pim, Stenström, Pernilla, Till, Holger, Van der Steeg, Lideke, Van Rooij, Iris, Volk, Patrick, Wester, Tomas, Zwink, Nadine, and On behalf of the ARM-Net Consortium
- Published
- 2017
- Full Text
- View/download PDF
43. Graphene-based integrated photonics for next-generation datacom and telecom
- Author
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Romagnoli, Marco, Sorianello, Vito, Midrio, Michele, Koppens, Frank H. L., Huyghebaert, Cedric, Neumaier, Daniel, Galli, Paola, Templ, Wolfgang, D’Errico, Antonio, and Ferrari, Andrea C.
- Published
- 2018
- Full Text
- View/download PDF
44. The Pediatric Colorectal and Pelvic Learning Consortium (PCPLC): rationale, infrastructure, and initial steps
- Author
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Reeder, Ron W., Wood, Richard J., Avansino, Jeffrey R., Levitt, Marc A., Durham, Megan M., Sutcliffe, Jonathan, Midrio, Paola, Calkins, Casey M., de Blaauw, Ivo, Dickie, Belinda Hsi, Rollins, Michael D., and For the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC)
- Published
- 2018
- Full Text
- View/download PDF
45. Graphene–silicon phase modulators with gigahertz bandwidth
- Author
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Sorianello, V., Midrio, M., Contestabile, G., Asselberghs, I., Van Campenhout, J., Huyghebaert, C., Goykhman, I., Ott, A. K., Ferrari, A. C., and Romagnoli, M.
- Published
- 2018
- Full Text
- View/download PDF
46. Propranolol and infantile hemangiomas: Outcome from a tricentric study
- Author
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Benetton, C., primary, Pace, MR. Di, additional, De Corti, F., additional, Cimador, M., additional, Gamba, P., additional, and Midrio, P., additional
- Published
- 2023
- Full Text
- View/download PDF
47. Prenatal diagnosis of hypospadias: postnatal outcome and implications for prenatal counselling
- Author
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Nappo, S. Gerocarni, primary, Gobbi, D., additional, Cerchia, E., additional, Pagliara, C., additional, Sciarrone, A., additional, Catti, M., additional, Brancalente, G., additional, and Midrio, P., additional
- Published
- 2022
- Full Text
- View/download PDF
48. First trimester lower abdominal cysts as early predictor of anorectal malformations.
- Author
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Erculiani, Marta, Trovalusci, Emanuele, Zanatta, Cinzia, De Lorenzis, Maria Sonia, Filippi, Elisa, Bracalente, Gabriella, and Midrio, Paola
- Abstract
Introduction: Prenatal ultrasound diagnosis of anorectal malformations (ARMs) is challenging and often missed as direct visualization of the anal sphincter is not routinely performed, plus the technique is operator-dependent and inaccurate, also in expert hands. Other indirect signs, such as rectosigmoid overdistension or intraluminal calcifications, are occasionally present in late pregnancy. The detection of a cyst of the lower abdomen in the first trimester may be an early sign of ARM. Here we reported our experience and a review of the literature of such cases. Material and methods: Isolated cases of lower abdomen cysts encountered in the first trimester at the Prenatal Diagnosis Unit during the last 5 years were retrieved and compared with those found in literature. Post-natal clinical data were analyzed to check the presence and type of malformations. Results: A total of three cases of lower abdomen cysts were found in our center and 13 in literature. In our case series all the cysts spontaneously regressed and were no longer visible since the second trimester of pregnancy, while in literature this was reported in only 4 out of 13 cases. ARM was confirmed in all patients at birth or post-mortem. Conclusions: The finding of a lower abdomen cyst during the first trimester of pregnancy could be an early predictive sign of ARM, even if it disappears during pregnancy. In these cases, we suggest mentioning to the parents the possibility of an ARM during the counseling and to refer the couple to a Colorectal Center. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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49. Urological Impact of Epididymo-orchitis in Patients with Anorectal Malformation: An ARM-Net Consortium Study
- Author
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Morandi, A., Fanjul, M., Iacobelli, B.D., Samuk, I., Aminoff, D., Midrio, P., Blaauw, I. de, Schmiedeke, E., Prato, A., Feitz, W.F.J., Steeg, H.J.J. van der, Minoli, D.G., Sloots, C. E. J., Fascetti-Leon, F., Makedonsky, I., Garcia, A., Stenström, P., Morandi, A., Fanjul, M., Iacobelli, B.D., Samuk, I., Aminoff, D., Midrio, P., Blaauw, I. de, Schmiedeke, E., Prato, A., Feitz, W.F.J., Steeg, H.J.J. van der, Minoli, D.G., Sloots, C. E. J., Fascetti-Leon, F., Makedonsky, I., Garcia, A., and Stenström, P.
- Abstract
Item does not contain fulltext, INTRODUCTION: To investigate the current experience of the ARM-Net Consortium in the management of epididymo-orchitis (EO) in patients with anorectal malformations (ARMs), and to identify specific risk factors and the need for urological care involvement. MATERIALS AND METHODS: We retrospectively collected data of EO in patients with ARM between 2015 and 2019. Data on urological aspects, ARM type, surgical approach, associated anomalies, diagnosis, and treatment of EO were collected and analyzed. RESULTS: Twenty-nine patients were reported by 12 centers. Twenty-six patients with EO (90%) had ARM with a rectourinary fistula. Median age at first EO was 2 years (range: 15 days-27 years). Twenty patients (69%) experienced multiple EO, and 60% of recurrences were ipsilateral. Associated urological anomalies included vesicoureteral reflux (48%), urethral anomalies (41%), neurogenic bladder (41%), and ectopic vas (10%). A positive urine culture during EO was present in 69%. EO was treated with antibiotics (90%), limiting surgical exploration to 14%. Prevention of recurrences included surgery (bulking agents 15%, vasectomy 15%, and orchiectomy 5%) and antibiotic prophylaxis (20%). CONCLUSION: Urologists may encounter patients with EO in ARM patients, frequently with positive urine culture. An appropriate urologic work-up for most ARM patients is necessary to identify and treat underlying risk factors. A practical scheme for the work-up is suggested for a close collaboration between pediatric surgeons and urologists.
- Published
- 2022
50. Renal transplantation in children weighing <15 kg: does concomitant lower urinary tract dysfunction influence the outcome?
- Author
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Ghirardo, Giulia, Midrio, Paola, Zucchetta, Pietro, Gamba, PierGiorgio, Zanon, GiovanniFranco, Murer, Luisa, and Castagnetti, Marco
- Published
- 2015
- Full Text
- View/download PDF
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