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A globalização trouxe diversas vantagens ao mundo empresarial, uma delas é a criação de novas empresas, principalmente as pequenas e micro empresas tiveram um crescimento considerável, mas o cenário econômico passou por diversas transformações políticas, sociais e econômicas, fazendo com que muitas empresas não conseguissem mais sobreviver ao novo mercado. A recuperação judicial trata-se de reorganizar a saúde geral da empresa, economicamente, administrativamente e financeiramente em suas atividades. A recuperação judicial (RJ) tem por objetivo recuperar a empresa, a fim de evitar sua falência. Dessa forma, a empresa terá a possibilidade de apresentar aos seus credores em juízo, formas para quitação dos débitos. Também continuará a oferecer seus serviços, gerar empregos e pagar impostos, tão necessários para manutenção das receitas públicas. O objetivo do presente trabalho é analisar a Lei 11.101/2005 que prevê a possibilidade de reestruturação das empresas economicamente viáveis que passem por dificuldades momentâneas, mantendo os empregos e os pagamentos aos credores, dessa forma foi necessário compreender a Lei 11.101/05 para entender sua importância na reestruturação das empresas. Foi realizado um estudo sobre a Lei 11.101/05, para descrever o processo da recuperação judicial de empresas, relatando sobre as fases da recuperação judicial.

The Cretaceous is generally conceived as one of the warmest geological periods in Earth history. The link between climate and plant distribution is here highlighted on the basis of palynological analyses. An upper Aptian well section from the Sergipe Basin in northeastern Brazil documents four cycles of dry–wet oscillations, based on palynological evidence. The cycles show a general trend of acceleration of the hydrological cycle. Dry periods are recorded mainly at the base of the section, with changes to more humid periods upwards. The dry periods are characterized by high to very high abundance of Classopollis classoides pollen grains. Already in the wet periods a conspicuous change in vegetation is recorded, with an increase in fern spores and upland flora, in particular Araucariacites australis pollen grains. The replacement of Classopollis by Araucariacites and ferns reflects a change from dry to wet conditions. The first dry–wet cycle (DWC-1) is recorded in the dominantly non-marine phase. At the base of this first cycle, intensive growth of anhydrite nodules is recorded. However, in beds overlying the evaporites, there is a conspicuous increase in flora associated with humid conditions (ferns and upland flora). DWC-2 starts with a pronounced peak of dinoflagellate cysts, which decrease abruptly accompanied by an increase in xerophytic flora (e.g., Classopollis classoides, Equisetosporites spp.). The abundance of xerophytic flora decreases upwards to give room for high abundances of fern spores, upland flora (e.g., Araucariacites australis, Cicatricosisporites spp.) and, in particular, dinoflagellate cysts. DWC-3 starts with a short interval containing a moderate abundance of xerophytes and a conspicuous wet flora and marine elements. With rising humidity, fern spore diversity also increased, suggesting that humidity was an important factor for the increase in diversity of this group. DWC-4 records minor peaks of xerophytic flora and a dominance of fern spores and upland flora. The progressive change in flora may be the result of displacement of the Intertropical Convergence Zone (ITCZ) and a relative sea-level rise.

Submerged macrophytes, zooplankton and phytoplankton surround reservoirs are still need knowledge about ecology and influence in water quality in reservoirs of America Latina. The control of the biomass formation, low nutrient loadings, algal growth and diversity are key points to acquire water quality. We investigated evidences of submerged macrophytes enhance water quality and planktonic assemblages in two bays surround reservoir. Samples for water transparency, nutrients (phosphorus and nitrogen mg/L -1 ), phytoplankton, and zooplankton were collected between littoral with macrophytes and limnetic areas. Analyses with Standard Protocols were applied to make comparisons of these parameters. Our data show both bays are Eutrophized, the Secchi disk value was high (3.8 and 3.9 m), low concentration of phosphorus (means= 0.03 and 0.05 mg/L -1 ) and nitrogen (0.4 and 0.9 mg/L -1 ). Chlorophyll- a exhibited high biomass formation during the dry period (49 and 61 μg/ L -1 ). Egeria densa cover a wide range in littoral areas (66% and 40%). Phytoplankton was represented by 13 species, including Cyanophyta (5,292 to 717 cell /mL -1 ) in high densities. Zooplankton comprised 77 species of Rotifera, 18 of Cladocera and three Copepoda, and densities varied between 3,711 and 2,232 org.m -3 in the littoral areas. The Re-oligotrophication and restoration of these bays can be used combining biological methods knowledge and technical experimentation. New approaches to adapted management measures to advance research and to improve water quality is a next step in a near future of reservoirs from Northeast Brazil. RESUMO O conhecimento sobre a ecologia e influencia da macrofitas submersas, zooplâncton e fitoplâncton na qualidade da agua ainda e insipiente em reservatorios da America Latina. O controle da formacao de biomassa, crescimento algal, baixa carga de nutrientes, e a diversidade sao pontos-chave. Investigamos evidencias do papel das macrofitas submersas na qualidade da agua e assembleias planctonicas em duas baias formadas de um reservatorio. Amostragem para analises da transparencia da agua, nutrientes (fosforo e nitrogenio mg / L -1 ), fitoplâncton e zooplâncton (riqueza e densidades) foram coletadas entre areas litorâneas com macrofitas e na limnetica. Analises foram realizadas com protocolos padrao para comparacoes desses parâmetros entre as baias. A transparencia foi alta (medias de 3.8 e 3.9 m), baixa concentracao do fosforo (medias = 0.03 e 0.05 mg / L -1 ) e nitrogenio (0.4 e 0.9 mg / L - 1 ), ambas as baias estao eutrofizadas. A Chlorofila- a teve alta biomassa (49 e 61 μg/ L -1 ). Egeria densa cobre amplas areas no litoral (66% e 40%), a riqueza do fitoplâncton incluiu 13 especies, das quais Cyanophyta (5,292 a 717 celulas / mL -1 ) em altas densidades. O zooplâncton incluiu especies Rotifera, Cladocera e Copepoda (77; 18; 03). As densidades do zooplâncton foram altas (3,711 e 2,232 org.m -3 ) no litoral. A oligotrofia e restauracao das baias podem ser adquiridas combinando conhecimento sobre metodos biologicos e experimentacao tecnica. Novas abordagens e medidas de manejo para avancar nas pesquisas da agua em reservatorios sao o futuro e consiste no proximo passo no Nordeste do Brasil. Palavras-chave: Qualidade da agua, interacoes troficas, Brasil, Semi-arido, Rio Sao Francisco.

O objetivo do presente estudo consiste em conhecer como tem se efetivado o trabalho da rede de prote??o ? crian?a e o adolescente v?tima de viol?ncia na regi?o Centro, Ilhas, Humait? de Porto Alegre, na perspectiva da intersetorialidade, a fim de identificar alternativas para a qualifica??o das pol?ticas de prote??o integral deste segmento social. Pesquisou-se como o fen?meno da viol?ncia com crian?as e adolescentes se manifesta na rede de prote??o; quais os servi?os, programas e pol?ticas s?o acionados; como s?o realizados os atendimentos, encaminhamentos e acompanhamentos; como s?o desenvolvidas as a??es intersetoriais na rede de prote??o da crian?a e do adolescente v?tima de viol?ncia; quais estrat?gias s?o utilizadas pelos profissionais para enfrentar os desafios desta rede; e quais as sugest?es s?o elencadas pelos profissionais para qualificar o trabalho na perspectiva da intersetorialidade. Trata-se de um estudo qualitativo, baseado no m?todo dial?tico-cr?tico, desenvolvido atrav?s de pesquisa documental, que analisou legisla??es que norteiam a constitui??o dos direitos das crian?as e dos adolescentes, e da pesquisa emp?rica, que utilizou a observa??o participante e sistem?tica de treze (13) reuni?es realizadas na rede Centro, Ilhas e Humait?, na cidade de Porto Alegre, duas (2) entrevistas individuais e semi-estruturadas com os conselheiros tutelares da regi?o e um (1) grupo focal com os profissionais que atuam na rede de prote??o da crian?a e adolescente, atingindo um total de oitenta e tr?s (83) sujeitos. As informa??es coletadas foram analisadas atrav?s da t?cnica de an?lise de conte?do de Bardin (2009) e do software QSR NVivo pro vers?o 11. Atrav?s deste estudo aponta-se que as crian?as e os adolescentes foram e permanecem sendo destinat?rios de viol?ncias que se acirram com as desigualdades sociais geradas pelo modo de produ??o capitalista, destacando-se a pobreza, o abandono, a repress?o, a neglig?ncia, o abuso sexual, a viol?ncia verbal, psicol?gica, f?sica, institucional e estrutural. Como decorr?ncia de lutas hist?ricas pela garantia dos direitos humanos de crian?as e adolescentes, e tendo em vista a participa??o do pa?s em pactos internacionais voltados estes direitos, observaram-se avan?os civilizat?rios na cria??o de aparatos legais e normativas que se prop?em a enfrentar a viol?ncia contra esta popula??o. O mapeamento da rede de prote??o da crian?a e do adolescente v?tima de viol?ncia na cidade de Porto Alegre permitiu identificar que as principais pol?ticas p?blicas e sociais que a comp?em s?o as pol?ticas de sa?de, assist?ncia social, educa??o, seguran?a p?blica, direitos humanos e justi?a atrav?s das quais se articulam v?rios ?rg?os de prote??o da crian?a e do adolescente. Quanto ? materializa??o da intersetorialidade na rede, a pesquisa evidenciou experi?ncias concretas do trabalho articulado a fim de contemplar as m?ltiplas demandas que perpassam as vidas dos usu?rios relacionadas ? viol?ncia na inf?ncia e na adolesc?ncia. As informa??es coletadas apontam para o car?ter contradit?rio acerca da intersetorialidade, que tanto permite maior efetividade nas estrat?gias de enfrentamento ? viol?ncia contra crian?as e adolescentes, quanto atua como mecanismo que oculta as fragilidades da rede de prote??o. Evidenciou-se, tamb?m, que quest?es relacionadas ? precariza??o das condi??es e rela??es de trabalho da rede de prote??o da crian?a e do adolescente impactam nos trabalhadores sociais e tamb?m nos usu?rios dos servi?os. Quanto ?s pot?ncias e possibilidades da rede, foi poss?vel observar que os trabalhadores sociais que nela atuam, compartilham um direcionamento ?tico-pol?tico voltado a um projeto societ?rio transformador, orientado por ideais como a defesa dos direitos humanos das crian?as e dos adolescentes, de melhores condi??es de vida e de trabalho e de outras lutas absorvidas da realidade que fortalecem a sua articula??o enquanto sujeito coletivo part?cipe de movimentos de resist?ncia ?s mais diversas formas de viol?ncias. The objective of the present study is to know how the work of the child and adolescent victim of violence protection network in the Central, Islands and Humait? region of Porto Alegre has been carried out in the perspective of the intersectoriality in order to identify alternatives for the qualification of the integral protection policies of this social segment. It was investigated how the phenomenon of violence with children and adolescents manifests itself in the protection network; what services, programs and policies are triggered; how the care, referrals and follow-ups are performed; how intersectoral actions are developed in the network for the protection of children and adolescent victims of violence; what strategies are used by professionals to face the challenges of this network; and which suggestions are listed by professionals to qualify the work from the perspective of intersectoriality. It is a qualitative study, based on the dialectical-critical method, developed through documentary research, which analyzed laws that guide the constitution of the rights of children and adolescents, and empirical research, which used the participant and systematic observation of thirteen (13) meetings held at the Centro, Ilhas and Humait? protection network in the city of Porto Alegre, two (2) individual and semi-structured interviews with the region's guardian counselors and one (1) focus group with professionals working in the protection of children and adolescents, reaching a total of eighty-three (83) subjects. The information collected was analyzed through the content analysis technique of Bardin (2009) and the software QSR NVivo pro version 11. Through this study it is pointed out that children and adolescents were and remain the target of violence that worsens with the social inequalities generated by the capitalist mode of production, such as poverty, neglect, repression, neglect, sexual abuse, verbal, psychological, physical, institutional and structural violence. As a result of historical struggles to guarantee the human rights of children and adolescents, and in view of the country's participation in international pacts aimed to this rights, civilizational advances have been noted in the creation of legal and normative apparatuses that aim to face the violence against this population. The mapping of the protection network of the child and adolescent victim of violence in the city of Porto Alegre allowed identifying that the main public and social policies that comprise it are health, welfare, education, public security, human rights, justice policies, through of which several organs of protection of the child and the adolescent are articulated. As for the materialization of the intersectoriality in the network, the research evidenced concrete experiences of articulated work in order to contemplate the multiple demands that permeate the lives of users related to violence in childhood and adolescence. The information gathered points to the contradictory nature of the intersectoral approach, which allows for greater effectiveness in coping with violence against children and adolescents, and acts as a mechanism that hides the fragilities of the protection network. It was also evidenced that issues related to the precariousness of the working conditions and relationships of the protection network of child and adolescent has impact on social workers and also on users of services. Regarding the powers and possibilities of the network, it was possible to observe that the social workers who act in it share an ethical-political orientation directed towards a transformative societal project, guided by ideals such as the protection of the human rights of children and adolescents, better conditions life and work and other struggles absorbed from reality that strengthen their articulation as a collective subject participant in movements of resistance to the most diverse forms of violence. Conselho Nacional de Pesquisa e Desenvolvimento Cient?fico e Tecnol?gico - CNPq

In this study, we compared the results of potency determination of recombinant human erythropoietin (rhEPO) obtained between 2010 and 2012 by the National Institute of Quality Control in Health (INCQS/Fiocruz), i.e., the National Control Laboratory (NCL), and by a manufacturer of rhEPO. In total, 47 different batches of commercially prepared rhEPO (alpha isoform) were analyzed. All results, including those of the control and warning limits, remained within the limits recommended by European Pharmacopoeia (Ph. Eur.). All relative error (RE) values were less than ± 30%, wh ereas most were approximately ± 20%. Applying the Bland-Altman plot, only two of 47 values remained outside the limits of agreement (LA). In addition, agreement of potency determination between INCQS and the manufacturer coefficient of variation of reproducibility (% CVR) was considered satisfactory. Taken together, our results demonstrate (i.) the potency assay of rhEPO performed at INCQS, is standardized and controlled, (ii.) the comparison of our results with those of the manufacturer, revealed an adequate inter-laboratory variation, and (iii.) the critical appraisal proposed here appears to be a feasible tool to assess the reproducibility of biological activity, providing additional information regarding monitoring and production consistency to manufacturers and NCLs.

Introduction Radiation therapy skin reactions are one of the most common side effects and can cause patient distress. In some cases, a severe radiation-induced skin reaction may limit delivered dose and potentially compromise treatment outcomes. There are some established best practices, but approaches and patient advice appear to have changed little over the years and are often based on tradition, not evidence. Canadian radiation therapy departments use different skin care products and approaches, and there has been little previous work to examine national practice patterns. Materials and Methods This study used a 42-item electronic survey based on a questionnaire designed by the UK Society and College of Radiographers. Practice data were collected related to assessment and prophylactics, interventions for prevention and management, and use of tools and guidelines. The final survey version was distributed to an identified radiation therapist-registered nurse dyad at each radiation therapy department in Canada (n = 44). Results Thirty-three departments responded (75% response rate). Results suggest a variation in national management. A number of departments continue to advise patients not to wash or use deodorant/antiperspirant despite having evidence to the contrary. There are also unnecessary restrictions on the use and timing of application of lotions as well as conflicting postradiotherapy skin care instructions regarding sun exposure. Conclusion The study demonstrated variation in practice across Canadian radiation therapy departments. National interprofessional guidelines could improve uptake of best practices. Where there is little evidence, a stress-reduction approach with more collaborative decision-making should be used to minimize patient disruption.

INTRODUCTION-It is growing the understanding that work accidents, besides involving individual aspects, imply social and organizational factors, evidencing the social character of the production of the work accident, which occurs in a particular mode of production and context of workers' social relations . Therefore, the research addressed here assumes this premise and investigates the living conditions at work and the ways of working life of workers in the oil and gas industry in Brazil.AIM: To investigate the social experiences of the subjects in the context of their social relations, focusing on the conditions of life at work and ways of life at work, highlighting the social dimension of exposure to risk and forms of protection at work.METHODS :Critical Dialectic - which supports categories such as historicity, totality, contradiction and mediation that illuminate the analyzes

Made available in DSpace on 2014-12-03T13:11:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-08-01Bitstream added on 2014-12-03T13:22:43Z : No. of bitstreams: 1 WOS000339127300059.pdf: 271496 bytes, checksum: aa65f6309ff0bf043616faabb3029d65 (MD5) The present study aimed to investigate the efficiency of exfoliative cytology by correlating the clinical lesions of oral squamous cell carcinoma (OSCC) with exfoliative cytology and histopathological findings. Cases of OSCC diagnosed between 1984 and 2010 were analyzed. The inclusion criteria for the present study were the availability of detailed clinical findings and a diagnosis of the disease through exfoliative cytology and histopathology. The cases were assessed and assigned scores, which were then submitted to modal expression analysis, which considers the higher frequency scores, thus relating the variables. The cytological findings demonstrated that the majority of the cases had malignant potential. Exfoliative cytology should be used as a supplementary tool for the diagnosis of OSCC, as it enables the early detection of these lesions. However, cytology should not be used as a substitute for histopathological examination. Univ Estadual Paulista, UNESP, Inst Sci & Technol, Dept Biosci & Oral Diag, BR-12245000 Sao Paulo, Brazil Univ Estadual Paulista, UNESP, Inst Sci & Technol, Dept Biosci & Oral Diag, BR-12245000 Sao Paulo, Brazil

Introduction:This research starts from the assumption that work accidents, in addition to fortuitous or individual phenomena, imply social and organizational factors, and highlights the social character of the production of the accident at work. For this reason, this study investigates the living conditions and the ways of workers in the oil and gas industry in Brazil.Aim:To analyze the human factors in the relationship with work accidents on oil platforms from the social dimensions.Methods:It is qualitative research and it has as instruments of collection the focal group and individual interviews with workers and managers of the platforms, participant observation, and documentary analysis.Results:The research is still being carried out, but some reflections are possible so far: accidents at work depend on the direct or indirect relationship of workers with the work process itself, the modalities of production of work, and management of work. Possible causes underlying the accident are the quality of life and the conceptions of health and safety. Associated with it are social constructs and the multifactorial causes of occupational accidents including the relations between acts and unsafe conditions.Discussion:The increase in outsourcing and the decrease in training quality, as well as the prioritization of production, targets the detriment of meeting safety criteria. There is a need to reassess labor management, safety policies, and outsourcing processes. Lack of awareness of the proper use of safety equipment and the organization of the work environment are major causes of work-related accidents. The human factor focuses on the individual, group, organizational, and social dimensions in complex interactions. The identification of social processes between working groups in empirical reality, the influence of elements of culture, organizational management, and their impacts on relations and on safe work performance allows an understanding of social risks.

A eritropoietina (EPO) é um hormônio glicoproteico que regula a eritropoiese, atuando sobre as células progenitoras eritroides na medula óssea. É produzido nos adultos principalmente no córtex renal. O Ministério da Saúde, em 2005, passou a fornecer produtos biológicos, dentre eles a rhEPO. A produção desses medicamentos proporcionou uma economia de 40 milhões por ano ao país. A rhEPO é produzida em células de ovário de hamster chinês – CHO. É uma glicoproteína composta de 165 aminoácidos. A massa molecular da estrutura glicosilada, que contém cerca de 40% de carboidratos, é de 30–34 kDa. A rhEPO é um medicamento que faz parte do Componente Especializado de Assistência Farmacêutica do Ministério da Saúde, como parte da Política Nacional de Assistência Farmacêutica. O INCQS recebeu, de 2007 a 2012, um total de 779 lotes de rhEPO para análise, 88% desse total corresponde à apresentação de 4000 UI/mL.

CAPES Macrófitas submersas promovem atributos das comunidades zooplanctônicas mediante estrutura física, transparência da água, habitat, e abrigo de predadores. Enquanto competem por luz e nutrientes, afetando negativamente o crescimento do fitoplâncton atuando nas interações de controle base-topo e promovendo efeito de controle topo-base do zooplâncton. Pouco foi investigado sobre o papel da vegetação submersa nas interações do zooplâncton e fitoplâncton em áreas sobre influência de reservatório no semiárido brasileiro. Nesse sentido, de maneira a identificar principais lacunas e perspectivas para estudos futuros sobre as macrófitas e interações tróficas enfatizando buscas por estudos realizados na América do Sul, realizamos uma análise cienciométrica, e acreditamos que o número de artigos na área exibirá uma tendência crescente ao longo dos anos, onde a América do Sul apresentará participação significativa tanto no número de publicações quanto na cooperação internacional. Além disso, com a finalidade de investigar se nas áreas com pressões pelos usos em reservatório e solo, plantas submersas são afetadas positivamente, e estruturam riqueza e abundância para o zooplâncton, e suas interações afetam negativamente o fitoplâncton durante quatro períodos, coletamos evidências de efeitos de controle base-topo e topo-base de macrófitas sobre o plâncton. Para tanto, comparamos atributos de comunidades e nutrientes dissolvidos em bancos de plantas na zona litorânea e centros correspondendo à pelágica. Para análise Cienciométrica, acessamos publicações usando base de dados internacional entre 1980 a 2015. A coleta do material no campo mediante navegação pelas áreas em distâncias superiores de 3.5km, com coletas simultâneas da cobertura vegetal, comunidades planctônicas e nutrientes nitrogenados e fósforo total dissolvido. Áreas de cobertura das plantas submersas foram estimadas por medição da proporção de presença e ausência de espécies em 24 pontos em transectos paralelos às margens em área superior a 3.5 km. Coletamos 24 amostras do fitoplâncton e de nutrientes. Para o zooplâncton, realizamos amostragem composta da coluna d’água na vertical e horizontal através de arrastos totalizando 48 amostras. A Cienciometria mostrou que o número de pesquisas sobre essas interações tróficas cresceram nos últimos anos na América do Sul, com contribuições do Brasil, Argentina e Uruguai. O conhecimento sobre as interações tróficas em tem norteado abordagens técnicas e pesquisas científicas em países temperados para melhorar a qualidade da água e restaurar lagos e reservatórios eutrofizados, mas a América do Sul avançou pouco. Constamos que o maior volume de artigos indexados tratou sobre a dinâmica e estrutura das assembléias aquáticas, teias e interações tróficas, para as quaias reservatórios e áreas alagadas receberam pouca atenção. Grande número de estudoscontemplam toda comunidade aquática e interações entre macrófitas, fitoplâncton zooplâncton e peixes. Com relação à pesquisa de campo, a macrófitas ocorreram em alta densidade e cobertura vegetal em 12 pontos por baía (60%; 70%) a diferentes profundidades (2m a 6m). Nas baías, fósforo (médias= 0.03 e 0.05 mg/L) e nitrogênio (0.4 e 0.9 mg/L) apresentaram baixas concentrações. A transparência de Secchi foi alta nas duas baías (>3.8). O fitoplâncton teve riqueza de 17 táxons, dos quais Cyanophyta e Bacillariophyta foram mais representativos. Baixas densidades registradas refletiram nos baixos valores clorofilaa (médias= 9 e 12 µg/l). O zooplâncton apresentou alta dissimilaridade na riqueza (97 spp.) dos Rotifera, Cladocera e Copepoda e abundância relativa, com densidades variando significativamente na zona pelágica (24 a 2013 ind./m³) e litorânea (28 a 1260 ind./m³) de ambas as baías. Nesse contexto, confrontando esses resultados com os dados encontrados da vegetação, juntamente com as baixas concentrações de nutrientes dissolvidos, clorofila-a e alta transparência da água (Secchi), há forte indício da ocorrência de interações com controles base-topo e topo-base sobre o fitoplâncton. Nossos dados suportam a hipótese de prováveis efeitos dessas interações estejam contribuindo para a manutenção das condições de transparência da água nas baías, favorecendo baixa riqueza e biomassa algal. Uma vez que o conhecimento sobre as interações tróficas, particularmente as que ocorrem em cascata tem sido desenvolvido com sucesso em na reestruturação e restauração da qualidade da água em diversos países. Esta pesquisa contribui para o conhecimento das interações mediadas pelas macrófitas, sobre o zooplâncton e fitoplâncton em áreas de influência de reservatórios. Contudo, estudos na área das interações tróficas mediadas pelas macrófitas poderão ser direcionados de maneira a atenuar assimetrias internacionais, encorajando o aumento da produtividade científica na América do Sul. Esforços para restaurar as baías no entorno do reservatório no Brasil poderão ser despendidos usando técnicas combinadas para aumentar a qualidade da água e incrementar atributos das comunidades aquáticas. Submerged macrophytes promote attributes of planktonic communities by physical structure, water transparency, habitat, and shelter from predators. As they compete for light and nutrients, affecting negatively the phytoplankton growing, mediated bottom-up and topdown control interactions of zooplankton. Little has been investigated on the role of submerged vegetation in the interactions of zooplankton and phytoplankton in areas of reservoir influence in the Brazilian semiarid region. In order to identify major gaps and perspectives for future studies of macrophytes and trophic interactions, emphasizing searches for studies in South America, we conducted a scientometric analysis. We believe that the number of articles in the area show an increasing tendency to over the years, where South America will present significant participation in both the number of publications and in international cooperation. In order to investigate the impact of land use areas surrounding reservoir in submerged plants on planktonic communities, during four periods, we collect evidence of bottom-up and top-down controls of macrophyte on plankton. Our hypothesis is that the macrophytes are affected positively in that areas, and at the same time, can provide structure for richness and abundance to zooplankton and their interactions affect phytoplankton negatively. In the field we compare attributes of communities and dissolved nutrients in plant beds in the littoral and pelagic zones. For scientometrical analysis, we access publications using international database from 1980 to 2015. In the field, the samples were collected by boat, where greater distances with simultaneous sampling of vegetation, plankton communities and nitrogenous nutrients and total phosphorus dissolved. The submerged plant coverage areas were estimated by reducing the proportion of presence and absence of species in 24 points in parallel transects an area greater than 3.5 km. We collected 24 samples of phytoplankton and nutrients. For zooplankton, carry out sample composed of the water column vertically and horizontally, through hauls totaling 48 samples. The scientometrical analysis results showed that the number of trophic interactions researches grown in recent years in South America, with contributions from Brazil, Argentina and Uruguay. We found that the highest volume of indexed articles deals with the dynamics and structure of aquatic assemblages, webs and trophic interactions. Reservoirs and wetlands have received little attention. The large number of studies includes all aquatic community and interactions between macrophytes, phytoplankton, zooplankton and fish. Macrophytes occurred in high density and vegetation cover at 12 points per bay (60%; 70%) at different depths (2m to 6m). In the bays, phosphorus (mean = 0.03 and 0.05 mg / L) and nitrogen (0.4 and 0.9 mg / L) had lower concentrations. We found high Secchi transparency (>3.8) for both bays. The phytoplankton richness was 17 taxa, of which Cyanophyta Bacillariophyta were most representative. Low densities recorded reflected in lower values Chlorophyll-a (mean = 9.12 µg/l). Zooplankton showed high dissimilarity in the richness (97 spp.) of rotifers, Cladocera and Copepoda, with relative abundance. Densities varying significantly in the pelagic (24-2013 ind./m³) and littoral zones (28-1260 ind./m³) of both the bays. In this context, comparing these results with data from the vegetation, along with low concentrations of dissolved nutrients, chlorophyll-a and high water transparency, there is strong evidence of the occurrence of macrophytes and zooplankton interactions with bottomup and top-down controls on phytoplankton. Our data support the hypothesis that probably, effects of these interactions are contributing to the maintenance of conditions of water transparency, favoring low richness and algal biomass. The knowledge of trophic interactions, particularly which occur in cascades, has been successfully developed in the restructuring and restoration of water quality in several countries. This research brings to contributes to the knowledge of macrophytes, zooplankton and phytoplankton interactions in areas influenced by reservoirs. However, studies in the area of trophic interactions mediated by macrophytes may be directed in order to mitigate international asymmetries by encouraging increased scientific productivity in South America. Efforts to restore the bays around the reservoir in Brazil may be spent using combined techniques to increase the quality water and increase attributes of aquatic communities.

A eritropoietina (EPO) e um hormonio glicoproteico que regula a eritropoiese, atuando sobre as celulas progenitoras eritroides na medula ossea. E produzido nos adultos principalmente no cortex renal. O Ministerio da Saude, em 2005, passou a fornecer produtos biologicos, dentre eles a rhEPO. A producao desses medicamentos proporcionou uma economia de 40 milhoes por ano ao pais. A rhEPO e produzida em celulas de ovario de hamster chines – CHO. E uma glicoproteina composta de 165 aminoacidos. A massa molecular da estrutura glicosilada, que contem cerca de 40% de carboidratos, e de 30–34 kDa. A rhEPO e um medicamento que faz parte do Componente Especializado de Assistencia Farmaceutica do Ministerio da Saude, como parte da Politica Nacional de Assistencia Farmaceutica. O INCQS recebeu, de 2007 a 2012, um total de 779 lotes de rhEPO para analise, 88% desse total corresponde a apresentacao de 4000 UI/mL.

O objetivo do estudo foi verificar a percepção ambiental de universitários de uma universidade federal destacando aspectos relativos à gestão integrada de resíduos sólidos, práticas pró-ambiental e principais problemas associados à sua falta em ambientes urbanos. Utilizou-se metodologia survey onde 135 acadêmicos de três cursos ligados às áreas de educação e ciências da saúde e ambiental participaram através de questionários semi-estruturados auto aplicados. Constatou-se que existem diferentes percepções dos acadêmicos sobra à gestão de resíduos sólidos no ambiente urbano. Por meio dos percentuais obtidos para os aspectos relativos à gestão os acadêmicos responderam ocorrer forma de coleta comum com 80%; 37% afirmou que não sabe o destino final dos resíduos, porém 75,5% responsabilizou o indivíduo pela geração dos mesmos. Observou-se que todos os estudantes praticam pelo menos uma das sete boas práticas pró-ambiental destacando o uso de papeis para rascunho e evitar uso de descartáveis com 60% e 66% respectivamente. O consumo não foi apontado como um problema, mas a educação foi apontada como capaz de influenciar as pessoas na mudança comportamental. A percepção dos reais problemas associados à falta de gestão integrada dos resíduos sólidos e suas consequências ambientais observadas, foram incontestáveis. The aim of the study was to assess the environmental perception of students of a Federal University emphasizing aspects of the Integrated Management of Solid Waste, pro-environmental practices and major problems associated with the lack of the management in urban environments. 135 students from three courses related to areas of education, health sciences and environmental participated through self applied semi-structured questionnaires. The results showed that students have different perceptions on solid waste management in urban environment. Through the responses obtained about the aspects of management, the academics responded that regular garbage collection (80%) is the most common where they live, 37% said affirmed that they do not know the final destination of the garbage, and 75.5% blamed the individuals for the problems caused by the excessive generation of waste. It was observed that all students practice at least one of the seven practice pro-environmental with emphasis on the use of scratch paper and control the use of disposable with 60% and 66%, respectively. Consumption was not mentioned as a environmental problem, but education was identified as the tool to influence people in changing attitudes. The perception of the real problems associated with the lack of integrated management of solid waste and its environmental consequences observed were indisputable.

FUNDAMENTO: O escore de risco TIMI (thrombolysis in myocardial infarction) é derivado de ensaio clínico envolvendo pacientes elegíveis para fibrinólise. Como o perfil de risco desses casos difere do encontrado em populações não selecionadas, é importante que se analise a aplicabilidade do escore em condições clínicas habituais. OBJETIVO: Avaliar o manejo e a evolução hospitalar de pacientes internados com infarto agudo do miocárdio conforme estratificação de risco pelo escore TIMI. MÉTODOS: Foram avaliados, retrospectivamente, 103 casos de infarto agudo do miocárdio com supradesnivelamento do segmento ST, admitidos no Hospital Nossa Senhora da Conceição, em Tubarão, nos anos de 2004 e 2005. Os casos foram analisados em três grupos de risco de acordo com o escore TIMI. RESULTADOS: A mortalidade hospitalar pós-infarto foi de 17,5%. No grupo de baixo risco não houve óbito. A mortalidade foi de 8,1% no grupo de médio risco e de 55,6% no de alto risco. O risco de morte para casos de alto risco foi 14,1 vezes maior em relação aos casos de médio e baixo risco (IC95% = 4,4 a 44,1 e p

The TIMI (Thrombolysis in Myocardial Infarction) risk score is derived from clinical trial involving patients who are eligible for fibrinolysis. As the risk profiles of these cases differ from those found in non-selected populations, it is important to review the applicability of the score in usual clinical conditions.To evaluate the management and clinical evolution of hospital inpatients with acute myocardial infarction, according to risk stratification by the TIMI score.We evaluated, retrospectively, 103 cases of acute myocardial infarction with ST-segment elevation admitted to the Hospital Nossa Senhora da Conceição - Tubarão, in 2004 and 2005. The cases were analyzed in three risk groups according to the TIMI score.The hospital mortality after infarction was 17.5%. In the low-risk group there was no death. The mortality was 8.1% in the medium risk group and 55.6% in the high-risk group. The risk of death in cases of high risk was 14.1 times higher than in the cases of medium and low risk (95% CI = 4.4 to 44.1 and p0.001). The chance of receiving fibrinolytic was 50% lower in the high-risk group in relation to the low risk group (95% CI = 0.27 to 0.85, p = 0.004).There was a progressive increase in mortality and incidence of in-hospital complications according to the stratification by the TIMI score. High risk patients received thrombolytic less frequently than the patients at low risk.

O fitoplâncton e o principal produtor primario dos ambientes costeiros, juntamente com o perifiton que pode chegar a 46% da producao autotrofica nos ambientes aquaticos, sendo responsavel pelo inicio do fluxo de materia e energia da rede trofica destes ambientes. Deste modo as modificacoes na abundância e composicao das comunidades fitoplanctonicas e epifitas marinhas podem ser otimas indicadoras da qualidade da agua, respondendo com boa fidelidade a avaliacao de muitas agressoes ambientais, devido a sua resposta rapida as mudancas na qualidade da agua, alteracoes hidrologicas e climaticas. Parte da regiao metropolitana do Recife – PE, que abrange o litoral de Jaboatao dos Guararapes, Recife, Olinda e Paulista foi atingida pela erosao marinha prejudicando o potencial da orla para o turismo e o lazer. Desta forma, o conhecimento sobre a biologia e ecologia das microalgas planctonicas e epifitas e hoje prioritario para o adequado manejo e funcionamento dos ecossistemas aquaticos servindo como subsidio ambiental para integrar o projeto de recuperacao da orla maritima e recomposicao da areia das praias ao longo do litoral do Estado de Pernambuco. A B S T R A C T Phytoplankton are the main primary producer of coastal environments , along with the periphyton that can reach 46% of autotrophic production in aquatic environments , being responsible for initiating the flow of matter and energy of these trophic network environments . Thus changes in the abundance and composition of phytoplankton communities and marine epiphytic can be great indicators of water quality , responding with good fidelity assessment of many environmental stresses , due to its rapid response to changes in water quality, hydrological and climatic changes . Part of the metropolitan area of Recife - PE covering the coastline Jaboatao Guararapes , Recife , Olinda , and Paulista was hit by sea erosion undermining the potential of the waterfront for tourism and recreation . Thus , knowledge about the biology and ecology of planktonic and epiphytic microalgae is now a priority for the proper management and functioning of aquatic ecosystems serve as a subsidy to integrate environmental recovery project of rebuilding the waterfront and sandy beaches along the coast State of Pernambuco . Key-Words: phytoplankton , periphyton, coastal erosion , shoreline recovery , Pernambuco .

A Bacia do Rio Uma é uma das Bacias Hidrográficas mais importantes do Estado de Pernambuco, e vem enfrentando desastres causados por cheias. Em resposta as últimas enchentes ocorridas no Estado, o Governo de Pernambuco desenvolveu um Sistema de Controle de Cheias, com uma programação para o Rio Una, de construção de quatro barragens de contenção, represamento e regularização de abastecimento de água nas cidades circundantes. A qualidade da água após a transição de um ambiente lótico para lêntico poderá ser alterada e dependerá de diversos fatores ambientais. O fitoplâncton responde com boa fidelidade a essas mudanças. Nas bacias estudadas, foram identificados 45 táxons infragenéricos de organismos fitoplanctônicos pertencentes ao grupo das Ochorophyta (40%), Chlorophyta (20%), Charophyta (20%), Cyanophyta (13%) e Euglenophyta (7%). Sendo a divisão Ochrophyta mais representativa com relação à riqueza e frequência de ocorrência. Não ocorrem valores expressivos de densidade nas amostragens. Assim, estudar a composição e a dinâmica populacional da comunidade fitoplanctônica é de fundamental importância para o entendimento da sustentação e conservação desse ecossistema, sobretudo por se tratar de um ambiente em transição e pela carência de estudos na região. ABSTRACT A River Basin is one of the most important Watershed State of Pernambuco, and this has been facing disasters caused by floods. In response to the recent floods occurred in the State, the Government of Pernambuco developed a Flood Control System, with a schedule for the Rio Una, four-building check dams, impoundment and regulation of water supply in the surrounding towns. The water quality after the transition from a lotic to lentic may change and depend on various environmental factors. Phytoplankton responds with good fidelity to these changes. Basins studied, 46 were identified taxa of phytoplankton organisms belonging to the group Ochorophyta (40%), Chlorophyta (20%), Charophyta (20%), Cyanophyta (13%) and Euglenophyta (7%). As the division Ochrophyta more representative with respect to wealth and frequency of occurrence. No significant values occur in sampling density. Thus, studying the composition and population dynamics of phytoplankton is of fundamental importance for the understanding and support of the conservation of this ecosystem, mainly because it is a transitional environment and the lack of studies in the region. Keywords: Phytoplankton, Una River basin, impounding water.

O presente estudo apresenta especies de macrofitas aquaticas estudadas em sete estacoes de amostragem na Area Diretamente Afetada e Area de Influencia Direta no Riacho Seco na futura barragem de Brejao, regiao Agreste de Pernambuco-Brasil trazendo informacoes sobre sua indicacao como parâmetro no monitoramento da qualidade da agua. A amostragem ocorreu em marco de 2012 compreendendo o periodo seco, utilizou-se o metodo do Quadrado para quantificar a biomassa seca media, identificacao floristica das especies, Frequencia de Ocorrencia (F.O) e Formas de vida. 22 especies de macrofitas foram identificadas, onde Alternanthera philoxeroides , Commelina erecta , Cyperus articulatus , Egeria densa , Myriophyllum aquaticum, Nymphoides indica e Polygonum acuminatum foram algumas constantes com 55% d e F.O. Eichhornia crassipes, Lemna sp., Pistia stratiotes e Salvinia auriculata foram algumas das especies comuns com 45% . Quanto as formas de vida, 54% emergentes, 32% flutuante livre, 13% flutuante fixa e 1% submersa livre. Polygonum acuminatum apresentou a maior variacao de biomassa seca media em todas as estacoes, com 5,58±9,67 (gPS.m 2 ) na montante, 48,89±12,71 (gPS.m 2 ) na ADA I, 5,23±9,06 (gPS.m 2 ) na 500 m e 92,22±35,60 (gPS.m 2 ) na jusante II. Para os parâmetros fisico-quimicos 2 estacoes apresentaram media de oxigenio dissolvido abaixo do limite estabelecido pela Resolucao Conama 357; 5,0 mL, nitrato e nitrito apresentaram concentracoes de mg/L e mg/L padrao aceitavel para agua Classe II. Em detrimento da sua dinâmica as macrofitas aquaticas respondem por diversas alteracoes ambientais e podem ser usadas como parâmetro para monitorar a qualidade da agua . Palavras-chave: macrofitas aquaticas; regiao Agreste; qualidade da agua. Macrophytes as a Parameter in the Environmental Monitoring of Water Quality ABSTRACT This study presents species of aquatic macrophytes on 7 sampling stations in the Directly Affected Area and Direct Influence Area on Riacho Seco in future dam Brejao , Agrest region of Pernambuco, Brazil bringing about its indication as a parameter for monitoring water quality. Sampling occurred in March 2012 comprising the dry period, used the Quadrat method to quantify dry biomass average, floristic species identification , Frequency of Occurrence ( F.O) and Biological Forms. 22 species of macrophytes were identified where Alternanthera philoxeroides, Commelina erecta, Cyperus articulatus, Egeria densa , Myriophyllum aquaticum, Nymphoides indica e Polygonum acuminatum were some constants with 55% of F.O. Eichhornia crassipes, Lemna sp ., Pistia stratiotes, Salvinia auriculata were some of the common species with 45% . Regarding biological forms, 54% was emergent, 32% free-floating, 13% floating leaved and 1% rooted submersed. Polygonum acuminatum showed the greatest variation in average dry biomass in all stations , with 5,58±9,67 gPS.m 2 in Montante; 48,89±12,71 in ADA I; ,5,23±9,06 500 m and 92,22±35,60 in Jusante II. For the physicochemical parameters 2 stations had average dissolved oxygen below the limit established by Conama Resolution 357 357; 5,0 mL, nitrate and nitrite were concentrations with mg/L and mg/L acceptable standard for Class II water . To the detriment of its dynamic aquatic macrophytes account for various environmental changes and can be used as a parameter to monitoring the water quality . Keywords: aquatic macrophytes; water quality, Agreste region.