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3. Energy Transfer in Stability-Optimized Perovskite Nanocrystals

Author

Greiner, Michèle G., Singldinger, Andreas, Henke, Nina A., Lampe, Carola, Leo, Ulrich, Gramlich, Moritz, and Urban, Alexander S.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Materials Science
Abstract

Outstanding optoelectronic properties and a facile synthesis render halide perovskite nanocrystals (NCs) a promising material for nanostructure-based devices. However, the commercialization is hindered mainly by the lack of NC stability under ambient conditions and inefficient charge carrier injection. Here, we investigate solutions to both problems, employing methylammonium lead bromide (MAPbBr_3) NCs encapsulated in diblock copolymer core-shell micelles of tunable size. We confirm that the shell does not prohibit energy transfer, as FRET efficiencies between these NCs and 2D CsPbBr_3 nanoplatelets (NPLs) reach 73.6%. This value strongly correlates to the micelle size, with thicker shells displaying significantly reduced FRET efficiencies. Those high efficiencies come with a price, as the thinnest shells protect the encapsulated NCs less from environmentally induced degradation. Finding the sweet spot between efficiency and protection could lead to the realization of tailored energy funnels with enhanced carrier densities for high-power perovskite NC-based optoelectronic applications.

Published
2022
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4. Inverted triplications formed by iterative template switches generate structural variant diversity at genomic disorder loci

Author

Grochowski, Christopher M., Bengtsson, Jesse D., Du, Haowei, Gandhi, Mira, Lun, Ming Yin, Mehaffey, Michele G., Park, KyungHee, Höps, Wolfram, Benito, Eva, Hasenfeld, Patrick, Korbel, Jan O., Mahmoud, Medhat, Paulin, Luis F., Jhangiani, Shalini N., Hwang, James Paul, Bhamidipati, Sravya V., Muzny, Donna M., Fatih, Jawid M., Gibbs, Richard A., Pendleton, Matthew, Harrington, Eoghan, Juul, Sissel, Lindstrand, Anna, Sedlazeck, Fritz J., Pehlivan, Davut, Lupski, James R., and Carvalho, Claudia M.B.

Published
2024
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10. The Compact Linear Collider (CLIC) - 2018 Summary Report

Author

CLIC, The, collaborations, CLICdp, Charles, T. K., Giansiracusa, P. J., Lucas, T. G., Rassool, R. P., Volpi, M., Balazs, C., Afanaciev, K., Makarenko, V., Patapenka, A., Zhuk, I., Collette, C., Boland, M. J., Hoffman, A. C. Abusleme, Diaz, M. A., Garay, F., Chi, Y., He, X., Pei, G., Pei, S., Shu, G., Wang, X., Zhang, J., Zhao, F., Zhou, Z., Chen, H., Gao, Y., Huang, W., Kuang, Y. P., Li, B., Li, Y., Meng, X., Shao, J., Shi, J., Tang, C., Wang, P., Wu, X., Zha, H., Ma, L., Han, Y., Fang, W., Gu, Q., Huang, D., Huang, X., Tan, J., Wang, Z., Zhao, Z., Uggerhøj, U. I., Wistisen, T. N., Aabloo, A., Aare, R., Kuppart, K., Vigonski, S., Zadin, V., Aicheler, M., Baibuz, E., Brücken, E., Djurabekova, F., Eerola, P., Garcia, F., Haeggström, E., Huitu, K., Jansson, V., Kassamakov, I., Kimari, J., Kyritsakis, A., Lehti, S., Meriläinen, A., Montonen, R., Nordlund, K., Österberg, K., Saressalo, A., Väinölä, J., Veske, M., Farabolini, W., Mollard, A., Peauger, F., Plouin, J., Bambade, P., Chaikovska, I., Chehab, R., Delerue, N., Davier, M., Faus-Golfe, A., Irles, A., Kaabi, W., LeDiberder, F., Pöschl, R., Zerwas, D., Aimard, B., Balik, G., Blaising, J. -J., Brunetti, L., Chefdeville, M., Dominjon, A., Drancourt, C., Geoffroy, N., Jacquemier, J., Jeremie, A., Karyotakis, Y., Nappa, J. M., Serluca, M., Vilalte, S., Vouters, G., Bernhard, A., Bründermann, E., Casalbuoni, S., Hillenbrand, S., Gethmann, J., Grau, A., Huttel, E., Müller, A. -S., Peiffer, P., Perić, I., de Jauregui, D. Saez, Emberger, L., Graf, C., Simon, F., Szalay, M., van der Kolk, N., Brass, S., Kilian, W., Alexopoulos, T., Apostolopoulos, T., Gazis, E. N., Gazis, N., Kostopoulos, V., Kourkoulis, S., Heilig, B., Lichtenberger, J., Shrivastava, P., Dayyani, M. K., Ghasem, H., Hajari, S. S., Shaker, H., Ashkenazy, Y., Popov, I., Engelberg, E., Yashar, A., Abramowicz, H., Benhammou, Y., Borysov, O., Borysova, M., Levy, A., Levy, I., Alesini, D., Bellaveglia, M., Buonomo, B., Cardelli, A., Diomede, M., Ferrario, M., Gallo, A., Ghigo, A., Giribono, A., Piersanti, L., Stella, A., Vaccarezza, C., de Blas, J., Franceschini, R., D'Auria, G., Di Mitri, S., Abe, T., Aryshev, A., Fukuda, M., Furukawa, K., Hayano, H., Higashi, Y., Higo, T., Kubo, K., Kuroda, S., Matsumoto, S., Michizono, S., Naito, T., Okugi, T., Shidara, T., Tauchi, T., Terunuma, N., Urakawa, J., Yamamoto, A., Raboanary, R., Luiten, O. J., Stragier, X. F. D., Hart, R., van der Graaf, H., Eigen, G., Adli, E., Lindstrøm, C. A., Lillestøl, R., Malina, L., Pfingstner, J., Sjobak, K. N., Ahmad, A., Hoorani, H., Khan, W. A., Bugiel, S., Bugiel, R., Firlej, M., Fiutowski, T. A., Idzik, M., Moroń, J., Świentek, K. P., de Renstrom, P. Brückman, Krupa, B., Kucharczyk, M., Lesiak, T., Pawlik, B., Sopicki, P., Turbiarz, B., Wojtoń, T., Zawiejski, L. K., Kalinowski, J., Nowak, K., Żarnecki, A. F., Firu, E., Ghenescu, V., Neagu, A. T., Preda, T., Zgura, I. S., Aloev, A., Azaryan, N., Boyko, I., Budagov, J., Chizhov, M., Filippova, M., Glagolev, V., Gongadze, A., Grigoryan, S., Gudkov, D., Karjavine, V., Lyablin, M., Nefedov, Yu., Olyunin, A., Rymbekova, A., Samochkine, A., Sapronov, A., Shelkov, G., Shirkov, G., Soldatov, V., Solodko, E., Trubnikov, G., Tyapkin, I., Uzhinsky, V., Vorozhtov, A., Zhemchugov, A., Levichev, E., Mezentsev, N., Piminov, P., Shatilov, D., Vobly, P., Zolotarev, K., Jelisavčić, I. Božović, Kačarević, G., Dumbelović, G. Milutinović, Pandurović, M., Radulović, M., Stevanović, J., Vukasinović, N., Lee, D. -H., Ayala, N., Benedetti, G., Guenzel, T., Iriso, U., Marti, Z., Perez, F., Pont, M., Trenado, J., Ruiz-Jimeno, A., Vila, I., Calero, J., Dominguez, M., Garcia-Tabares, L., Gavela, D., Lopez, D., Toral, F., Gutierrez, C. Blanch, Boronat, M., Esperante, D., Fullana, E., Fuster, J., García, I., Gimeno, B., Lopez, P. Gomis, González, D., Perelló, M., Ros, E., Villarejo, M. A., Vnuchenko, A., Vos, M., Borgmann, Ch., Brenner, R., Ekelöf, T., Jacewicz, M., Olvegård, M., Ruber, R., Ziemann, V., Aguglia, D., Gonzalvo, J. Alabau, Leon, M. Alcaide, Tehrani, N. Alipour, Anastasopoulos, M., Andersson, A., Andrianala, F., Antoniou, F., Apyan, A., Arominski, D., Artoos, K., Assly, S., Atieh, S., Baccigalupi, C., Sune, R. Ballabriga, Caballero, D. Banon, Barnes, M. J., Garcia, J. Barranco, Bartalesi, A., Bauche, J., Bayar, C., Belver-Aguilar, C., Morell, A. Benot, Bernardini, M., Bett, D. R., Bettoni, S., Bettencourt, M., Bielawski, B., Garcia, O. Blanco, Kraljevic, N. Blaskovic, Bolzon, B., Bonnin, X. A., Bozzini, D., Branger, E., Brondolin, E., Brunner, O., Buckland, M., Bursali, H., Burkhardt, H., Caiazza, D., Calatroni, S., Campbell, M., Lasheras, N. Catalan, Cassany, B., Castro, E., Soares, R. H. Cavaleiro, Bastos, M. Cerqueira, Cherif, A., Chevallay, E., Cilento, V., Corsini, R., Costa, R., Cure, B., Curt, S., Gobbo, A. Dal, Dannheim, D., Daskalaki, E., Deacon, L., Degiovanni, A., De Michele, G., De Oliveira, L., Romano, V. Del Pozo, Delahaye, J. P., Delikaris, D., de Almeida, P. G. Dias, Dobers, T., Doebert, S., Doytchinov, I., Draper, M., Ramos, F. Duarte, Duquenne, M., Plaja, N. Egidos, Elsener, K., Esberg, J., Esposito, M., Evans, L., Fedosseev, V., Ferracin, P., Fiergolski, A., Foraz, K., Fowler, A., Friebel, F., Fuchs, J-F., Gaddi, A., Gamba, D., Fajardo, L. Garcia, Morales, H. Garcia, Garion, C., Gasior, M., Gatignon, L., Gayde, J-C., Gerbershagen, A., Gerwig, H., Giambelli, G., Gilardi, A., Goldblatt, A. N., Anton, S. Gonzalez, Grefe, C., Grudiev, A., Guerin, H., Guillot-Vignot, F. G., Gutt-Mostowy, M. L., Lutz, M. Hein, Hessler, C., Holma, J. K., Holzer, E. B., Hourican, M., Hynds, D., Ikarios, E., Levinsen, Y. Inntjore, Janssens, S., Jeff, A., Jensen, E., Jonker, M., Kamugasa, S. W., Kastriotou, M., Kemppinen, J. M. K., Khan, V., Kieffer, R. B., Klempt, W., Kokkinis, N., Kossyvakis, I., Kostka, Z., Korsback, A., Platia, E. Koukovini, Kovermann, J. W., Kozsar, C-I., Kremastiotis, I., Kröger, J., Kulis, S., Latina, A., Leaux, F., Lebrun, P., Lefevre, T., Leogrande, E., Linssen, L., Liu, X., Cudie, X. Llopart, Magnoni, S., Maidana, C., Maier, A. A., Durand, H. Mainaud, Mallows, S., Manosperti, E., Marelli, C., Lacoma, E. Marin, Marsh, S., Martin, R., Martini, I., Martyanov, M., Mazzoni, S., Mcmonagle, G., Mether, L. M., Meynier, C., Modena, M., Moilanen, A., Mondello, R., Cabral, P. B. Moniz, Irazabal, N. Mouriz, Munker, M., Muranaka, T., Nadenau, J., Navarro, J. G., Quirante, J. L. Navarro, Del Busto, E. Nebo, Nikiforou, N., Ninin, P., Nonis, M., Nisbet, D., Nuiry, F. X., Nürnberg, A., Ögren, J., Osborne, J., Ouniche, A. C., Pan, R., Papadopoulou, S., Papaphilippou, Y., Paraskaki, G., Pastushenko, A., Passarelli, A., Patecki, M., Pazdera, L., Pellegrini, D., Pepitone, K., Codina, E. Perez, Fontenla, A. Perez, Persson, T. H. B., Petrič, M., Pitman, S., Pitters, F., Pittet, S., Plassard, F., Popescu, D., Quast, T., Rajamak, R., Redford, S., Remandet, L., Renier, Y., Rey, S. F., Orozco, O. Rey, Riddone, G., Castro, E. Rodriguez, Roloff, P., Rossi, C., Rossi, F., Rude, V., Ruehl, I., Rumolo, G., Sailer, A., Sandomierski, J., Santin, E., Sanz, C., Bedolla, J. Sauza, Schnoor, U., Schmickler, H., Schulte, D., Senes, E., Serpico, C., Severino, G., Shipman, N., Sicking, E., Simoniello, R., Skowronski, P. K., Mompean, P. Sobrino, Soby, L., Sollander, P., Solodko, A., Sosin, M. P., Spannagel, S., Sroka, S., Stapnes, S., Sterbini, G., Stern, G., Ström, R., Stuart, M. J., Syratchev, I., Szypula, K., Tecker, F., Thonet, P. A., Thrane, P., Timeo, L., Tiirakari, M., Garcia, R. Tomas, Tomoiaga, C. I., Valerio, P., Vaňát, T., Vamvakas, A. L., Van Hoorne, J., Viazlo, O., Pinto, M. Vicente Barreto, Vitoratou, N., Vlachakis, V., Weber, M. A., Wegner, R., Wendt, M., Widorski, M., Williams, O. E., Williams, M., Woolley, B., Wuensch, W., Wulzer, A., Uythoven, J., Xydou, A., Yang, R., Zelios, A., Zhao, Y., Zisopoulos, P., Benoit, M., Sultan, D M S, Riva, F., Bopp, M., Braun, H. H., Craievich, P., Dehler, M., Garvey, T., Pedrozzi, M., Raguin, J. Y., Rivkin, L., Zennaro, R., Guillaume, S., Rothacher, M., Aksoy, A., Nergiz, Z., Yavas, Ö., Denizli, H., Keskin, U., Oyulmaz, K. Y., Senol, A., Ciftci, A. K., Baturin, V., Karpenko, O., Kholodov, R., Lebed, O., Lebedynskyi, S., Mordyk, S., Musienko, I., Profatilova, Ia., Storizhko, V., Bosley, R. R., Price, T., Watson, M. F., Watson, N. K., Winter, A. G., Goldstein, J., Green, S., Marshall, J. S., Thomson, M. A., Xu, B., You, T., Gillespie, W. A., Spannowsky, M., Beggan, C., Martin, V., Zhang, Y., Protopopescu, D., Robson, A., Apsimon, R. J., Bailey, I., Burt, G. C., Dexter, A. C., Edwards, A. V., Hill, V., Jamison, S., Millar, W. L., Papke, K., Casse, G., Vossebeld, J., Aumeyr, T., Bergamaschi, M., Bobb, L., Bosco, A., Boogert, S., Boorman, G., Cullinan, F., Gibson, S., Karataev, P., Kruchinin, K., Lekomtsev, K., Lyapin, A., Nevay, L., Shields, W., Snuverink, J., Towler, J., Yamakawa, E., Boisvert, V., West, S., Jones, R., Joshi, N., Bett, D., Bodenstein, R. M., Bromwich, T., Burrows, P. N., Christian, G. B., Gohil, C., Korysko, P., Paszkiewicz, J., Perry, C., Ramjiawan, R., Roberts, J., Coates, T., Salvatore, F., Bainbridge, A., Clarke, J. A., Krumpa, N., Shepherd, B. J. A., Walsh, D., Chekanov, S., Demarteau, M., Gai, W., Liu, W., Metcalfe, J., Power, J., Repond, J., Weerts, H., Xia, L., Zupan, J., Wells, J. D., Zhang, Z., Adolphsen, C., Barklow, T., Dolgashev, V., Franzi, M., Graf, N., Hewett, J., Kemp, M., Kononenko, O., Markiewicz, T., Moffeit, K., Neilson, J., Nosochkov, Y., Oriunno, M., Phinney, N., Rizzo, T., Tantawi, S., Wang, J., Weatherford, B., White, G., and Woodley, M.

Subjects
Physics - Accelerator Physics
Abstract

The Compact Linear Collider (CLIC) is a TeV-scale high-luminosity linear $e^+e^-$ collider under development at CERN. Following the CLIC conceptual design published in 2012, this report provides an overview of the CLIC project, its current status, and future developments. It presents the CLIC physics potential and reports on design, technology, and implementation aspects of the accelerator and the detector. CLIC is foreseen to be built and operated in stages, at centre-of-mass energies of 380 GeV, 1.5 TeV and 3 TeV, respectively. CLIC uses a two-beam acceleration scheme, in which 12 GHz accelerating structures are powered via a high-current drive beam. For the first stage, an alternative with X-band klystron powering is also considered. CLIC accelerator optimisation, technical developments and system tests have resulted in an increased energy efficiency (power around 170 MW) for the 380 GeV stage, together with a reduced cost estimate at the level of 6 billion CHF. The detector concept has been refined using improved software tools. Significant progress has been made on detector technology developments for the tracking and calorimetry systems. A wide range of CLIC physics studies has been conducted, both through full detector simulations and parametric studies, together providing a broad overview of the CLIC physics potential. Each of the three energy stages adds cornerstones of the full CLIC physics programme, such as Higgs width and couplings, top-quark properties, Higgs self-coupling, direct searches, and many precision electroweak measurements. The interpretation of the combined results gives crucial and accurate insight into new physics, largely complementary to LHC and HL-LHC. The construction of the first CLIC energy stage could start by 2026. First beams would be available by 2035, marking the beginning of a broad CLIC physics programme spanning 25-30 years., Comment: 112 pages, 59 figures; published as CERN Yellow Report Monograph Vol. 2/2018; corresponding editors: Philip N. Burrows, Nuria Catalan Lasheras, Lucie Linssen, Marko Petri\v{c}, Aidan Robson, Daniel Schulte, Eva Sicking, Steinar Stapnes

Published
2018
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14. The role of media professionals in perpetuating and disrupting stereotypes of women in Science, Technology, Engineering and Math (STEM) fields

Author

Charisse L'Pree Corsbie-Massay and Michele G. Wheatly

Subjects
gender, stereotype, discrimination, STEM, women in STEM, media, Communication. Mass media, P87-96
Abstract

Women continue to be underrepresented in the Science, Technology, Engineering and Mathematics (STEM) fields despite efforts to enhance interest and persistence at all levels in the educational pipeline. The “chilly” climate documented for girls and women in STEM exists within a broader communication climate established and reinforced by media professionals. The present study examined the role of media professionals in perpetuating stereotypes of women in STEM through two approaches (1) conducting interviews with seventeen STEM women about their engagement with media professionals and (2) surveying 105 media professionals about their stereotypes about science and scientists. STEM women report positive interactions with the media despite incidents of unprofessionalism, dissonance between the processes and pace of science vs. the media, an undercurrent of issues pertaining to gender and other forms of representation, and an ethical responsibility to engage with media. The survey of media professionals revealed persistent stereotypes about scientists across both genders, and these stereotypes were more pronounced among those who engaged with science as part of their job, particularly among those working in entertainment and advertising and those working outside of journalism and social media. To establish greater equity in STEM fields and the knowledge pipeline, communication scholars must investigate the role of media professionals in this process and consider best practices to disrupt media stereotypes about STEM women.

Published
2022
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15. An Epidemiological Study Comparing Cancer- and Non-Cancer-Associated Venous Thromboembolism in A Racially Diverse Southeastern United States County

Author

Peseski, Andrew M., primary, Kapoor, Sargam, additional, Kuchibhatla, Maragatha, additional, Adamski, Alys, additional, Abe, Karon, additional, Beckman, Michele G., additional, Reyes, Nimia L., additional, Richardson, Lisa C., additional, Saber, Ibrahim, additional, Schulteis, Ryan, additional, Singh, Bhavana Pendurthi, additional, Sitlinger, Andrea, additional, Thames, Elizabeth H., additional, and Ortel, Thomas L., additional

Published
2024
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17. Protocol: A multi-modal, physician-centered intervention to improve guideline-concordant prostate cancer imaging

Author

Danil V. Makarov, Shannon Ciprut, Matthew Kelly, Dawn Walter, Michele G. Shedlin, Ronald Scott Braithwaite, Craig T. Tenner, Heather T. Gold, Steven Zeliadt, and Scott E. Sherman

Subjects
Prostate cancer, Staging imaging, Guidelines, Implementation, Medicine (General), R5-920
Abstract

Abstract Background Almost half of Veterans with localized prostate cancer receive inappropriate, wasteful staging imaging. Our team has explored the barriers and facilitators of guideline-concordant prostate cancer imaging and found that (1) patients with newly diagnosed prostate cancer have little concern for radiographic staging but rather focus on treatment and (2) physicians trust imaging guidelines but are apt to follow their own intuition, fear medico-legal consequences, and succumb to influence from imaging-avid colleagues. We used a theory-based approach to design a multi-level intervention strategy to promote guideline-concordant imaging to stage incident prostate cancer. Methods We designed the Prostate Cancer Imaging Stewardship (PCIS) intervention: a multi-site, stepped wedge, cluster-randomized trial to determine the effect of a physician-focused behavioral intervention on Veterans Health Administration (VHA) prostate cancer imaging use. The multi-level intervention, developed according to the Theoretical Domains Framework (TDF) and Behavior Change Wheel, combines traditional physician behavior change methods with novel methods of communication and data collection. The intervention consists of three components: (1) a system of audit and feedback to clinicians informing individual clinicians and their sites about how their behavior compares to their peers’ and to published guidelines, (2) a program of academic detailing with the goal to educate providers about prostate cancer imaging, and (3) a CPRS Clinical Order Check for potentially guideline-discordant imaging orders. The intervention will be introduced to 10 participating geographically distributed study sites. Discussion This study is a significant contribution to implementation science, providing VHA an opportunity to ensure delivery of high-quality care at the lowest cost using a theory-based approach. The study is ongoing. Preliminary data collection and recruitment have started; analysis has yet to be performed. Trial registration CliniclTrials.gov NCT03445559. Prospectively registered on February 26, 2018

Published
2021
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18. Updated baseline for a staged Compact Linear Collider

Author

CLIC, The, collaborations, CLICdp, Boland, M. J., Felzmann, U., Giansiracusa, P. J., Lucas, T. G., Rassool, R. P., Balazs, C., Charles, T. K., Afanaciev, K., Emeliantchik, I., Ignatenko, A., Makarenko, V., Shumeiko, N., Patapenka, A., Zhuk, I., Hoffman, A. C. Abusleme, Gutierrez, M. A. Diaz, Gonzalez, M. Vogel, Chi, Y., He, X., Pei, G., Pei, S., Shu, G., Wang, X., Zhang, J., Zhao, F., Zhou, Z., Chen, H., Gao, Y., Huang, W., Kuang, Y. P., Li, B., Li, Y., Shao, J., Shi, J., Tang, C., Wu, X., Ma, L., Han, Y., Fang, W., Gu, Q., Huang, D., Huang, X., Tan, J., Wang, Z., Zhao, Z., Laštovička, T., Uggerhoj, U., Wistisen, T. N., Aabloo, A., Eimre, K., Kuppart, K., Vigonski, S., Zadin, V., Aicheler, M., Baibuz, E., Brücken, E., Djurabekova, F., Eerola, P., Garcia, F., Haeggström, E., Huitu, K., Jansson, V., Karimaki, V., Kassamakov, I., Kyritsakis, A., Lehti, S., Meriläinen, A., Montonen, R., Niinikoski, T., Nordlund, K., Österberg, K., Parekh, M., Törnqvist, N. A., Väinölä, J., Veske, M., Farabolini, W., Mollard, A., Napoly, O., Peauger, F., Plouin, J., Bambade, P., Chaikovska, I., Chehab, R., Davier, M., Kaabi, W., Kou, E., LeDiberder, F., Pöschl, R., Zerwas, D., Aimard, B., Balik, G., Baud, J. -P., Blaising, J. -J., Brunetti, L., Chefdeville, M., Drancourt, C., Geoffroy, N., Jacquemier, J., Jeremie, A., Karyotakis, Y., Nappa, J. M., Vilalte, S., Vouters, G., Bernard, A., Peric, I., Gabriel, M., Simon, F., Szalay, M., van der Kolk, N., Alexopoulos, T., Gazis, E. N., Gazis, N., Ikarios, E., Kostopoulos, V., Kourkoulis, S., Gupta, P. D., Shrivastava, P., Arfaei, H., Dayyani, M. K., Ghasem, H., Hajari, S. S., Shaker, H., Ashkenazy, Y., Abramowicz, H., Benhammou, Y., Borysov, O., Kananov, S., Levy, A., Levy, I., Rosenblat, O., D'Auria, G., Di Mitri, S., Abe, T., Aryshev, A., Higo, T., Makida, Y., Matsumoto, S., Shidara, T., Takatomi, T., Takubo, Y., Tauchi, T., Toge, N., Ueno, K., Urakawa, J., Yamamoto, A., Yamanaka, M., Raboanary, R., Hart, R., van der Graaf, H., Eigen, G., Zalieckas, J., Adli, E., Lillestøl, R., Malina, L., Pfingstner, J., Sjobak, K. N., Ahmed, W., Asghar, M. I., Hoorani, H., Bugiel, S., Dasgupta, R., Firlej, M., Fiutowski, T. A., Idzik, M., Kopec, M., Kuczynska, M., Moron, J., Swientek, K. P., Daniluk, W., Krupa, B., Kucharczyk, M., Lesiak, T., Moszczynski, A., Pawlik, B., Sopicki, P., Wojtoń, T., Zawiejski, L., Kalinowski, J., Krawczyk, M., Żarnecki, A. F., Firu, E., Ghenescu, V., Neagu, A. T., Preda, T., Zgura, I-S., Aloev, A., Azaryan, N., Budagov, J., Chizhov, M., Filippova, M., Glagolev, V., Gongadze, A., Grigoryan, S., Gudkov, D., Karjavine, V., Lyablin, M., Olyunin, A., Samochkine, A., Sapronov, A., Shirkov, G., Soldatov, V., Solodko, A., Solodko, E., Trubnikov, G., Tyapkin, I., Uzhinsky, V., Vorozhtov, A., Levichev, E., Mezentsev, N., Piminov, P., Shatilov, D., Vobly, P., Zolotarev, K., Jelisavcic, I. Bozovic, Kacarevic, G., Lukic, S., Milutinovic-Dumbelovic, G., Pandurovic, M., Iriso, U., Perez, F., Pont, M., Trenado, J., Aguilar-Benitez, M., Calero, J., Garcia-Tabares, L., Gavela, D., Gutierrez, J. L., Lopez, D., Toral, F., Moya, D., Jimeno, A. Ruiz, Vila, I., Argyropoulos, T., Gutierrez, C. Blanch, Boronat, M., Esperante, D., Faus-Golfe, A., Fuster, J., Martinez, N. Fuster, Muñoz, N. Galindo, García, I., Navarro, J. Giner, Ros, E., Vos, M., Brenner, R., Ekelöf, T., Jacewicz, M., Ögren, J., Olvegård, M., Ruber, R., Ziemann, V., Aguglia, D., Tehrani, N. Alipour, Andersson, A., Andrianala, F., Antoniou, F., Artoos, K., Atieh, S., Sune, R. Ballabriga, Barnes, M. J., Garcia, J. Barranco, Bartosik, H., Belver-Aguilar, C., Morell, A. Benot, Bett, D. R., Bettoni, S., Blanchot, G., Garcia, O. Blanco, Bonnin, X. A., Brunner, O., Burkhardt, H., Calatroni, S., Campbell, M., Lasheras, N. Catalan, Bastos, M. Cerqueira, Cherif, A., Chevallay, E., Constance, B., Corsini, R., Cure, B., Curt, S., Dalena, B., Dannheim, D., De Michele, G., De Oliveira, L., Deelen, N., Delahaye, J. P., Dobers, T., Doebert, S., Draper, M., Ramos, F. Duarte, Dubrovskiy, A., Elsener, K., Esberg, J., Esposito, M., Fedosseev, V., Ferracin, P., Fiergolski, A., Foraz, K., Fowler, A., Friebel, F., Fuchs, J-F., Rojas, C. A. Fuentes, Gaddi, A., Fajardo, L. Garcia, Morales, H. Garcia, Garion, C., Gatignon, L., Gayde, J-C., Gerwig, H., Goldblatt, A. N., Grefe, C., Grudiev, A., Guillot-Vignot, F. G., Gutt-Mostowy, M. L., Hauschild, M., Hessler, C., Holma, J. K., Holzer, E., Hourican, M., Hynds, D., Levinsen, Y. Inntjore, Jeanneret, B., Jensen, E., Jonker, M., Kastriotou, M., Kemppinen, J. M. K., Kieffer, R. B., Klempt, W., Kononenko, O., Korsback, A., Platia, E. Koukovini, Kovermann, J. W., Kozsar, C-I., Kremastiotis, I., Kulis, S., Latina, A., Leaux, F., Lebrun, P., Lefevre, T., Linssen, L., Cudie, X. Llopart, Maier, A. A., Durand, H. Mainaud, Manosperti, E., Marelli, C., Lacoma, E. Marin, Martin, R., Mazzoni, S., Mcmonagle, G., Mete, O., Mether, L. M., Modena, M., Münker, R. M., Muranaka, T., Del Busto, E. Nebot, Nikiforou, N., Nisbet, D., Nonglaton, J-M., Nuiry, F. X., Nürnberg, A., Olvegard, M., Osborne, J., Papadopoulou, S., Papaphilippou, Y., Passarelli, A., Patecki, M., Pazdera, L., Pellegrini, D., Pepitone, K., Codina, E. Perez, Fontenla, A. Perez, Persson, T. H. B., Petrič, M., Pitters, F., Pittet, S., Plassard, F., Rajamak, R., Redford, S., Renier, Y., Rey, S. F., Riddone, G., Rinolfi, L., Castro, E. Rodriguez, Roloff, P., Rossi, C., Rude, V., Rumolo, G., Sailer, A., Santin, E., Schlatter, D., Schmickler, H., Schulte, D., Shipman, N., Sicking, E., Simoniello, R., Skowronski, P. K., Mompean, P. Sobrino, Soby, L., Sosin, M. P., Sroka, S., Stapnes, S., Sterbini, G., Ström, R., Syratchev, I., Tecker, F., Thonet, P. A., Timeo, L., Timko, H., Garcia, R. Tomas, Valerio, P., Vamvakas, A. L., Vivoli, A., Weber, M. A., Wegner, R., Wendt, M., Woolley, B., Wuensch, W., Uythoven, J., Zha, H., Zisopoulos, P., Benoit, M., Pinto, M. Vicente Barreto, Bopp, M., Braun, H. H., Divall, M. Csatari, Dehler, M., Garvey, T., Raguin, J. Y., Rivkin, L., Zennaro, R., Aksoy, A., Nergiz, Z., Pilicer, E., Tapan, I., Yavas, O., Baturin, V., Kholodov, R., Lebedynskyi, S., Miroshnichenko, V., Mordyk, S., Profatilova, I., Storizhko, V., Watson, N., Winter, A., Goldstein, J., Green, S., Marshall, J. S., Thomson, M. A., Xu, B., Gillespie, W. A., Pan, R., Tyrk, M. A, Protopopescu, D., Robson, A., Apsimon, R., Bailey, I., Burt, G., Constable, D., Dexter, A., Karimian, S., Lingwood, C., Buckland, M. D., Casse, G., Vossebeld, J., Bosco, A., Karataev, P., Kruchinin, K., Lekomtsev, K., Nevay, L., Snuverink, J., Yamakawa, E., Boisvert, V., Boogert, S., Boorman, G., Gibson, S., Lyapin, A., Shields, W., Teixeira-Dias, P., West, S., Jones, R., Joshi, N., Bodenstein, R., Burrows, P. N., Christian, G. B., Gamba, D., Perry, C., Roberts, J., Clarke, J. A., Collomb, N. A., Jamison, S. P., Shepherd, B. J. A., Walsh, D., Demarteau, M., Repond, J., Weerts, H., Xia, L., Wells, J. D., Adolphsen, C., Barklow, T., Breidenbach, M., Graf, N., Hewett, J., Markiewicz, T., McCormick, D., Moffeit, K., Nosochkov, Y., Oriunno, M., Phinney, N., Rizzo, T., Tantawi, S., Wang, F., Wang, J., White, G., and Woodley, M.

Subjects
Physics - Accelerator Physics, High Energy Physics - Experiment
Abstract

The Compact Linear Collider (CLIC) is a multi-TeV high-luminosity linear e+e- collider under development. For an optimal exploitation of its physics potential, CLIC is foreseen to be built and operated in a staged approach with three centre-of-mass energy stages ranging from a few hundred GeV up to 3 TeV. The first stage will focus on precision Standard Model physics, in particular Higgs and top-quark measurements. Subsequent stages will focus on measurements of rare Higgs processes, as well as searches for new physics processes and precision measurements of new states, e.g. states previously discovered at LHC or at CLIC itself. In the 2012 CLIC Conceptual Design Report, a fully optimised 3 TeV collider was presented, while the proposed lower energy stages were not studied to the same level of detail. This report presents an updated baseline staging scenario for CLIC. The scenario is the result of a comprehensive study addressing the performance, cost and power of the CLIC accelerator complex as a function of centre-of-mass energy and it targets optimal physics output based on the current physics landscape. The optimised staging scenario foresees three main centre-of-mass energy stages at 380 GeV, 1.5 TeV and 3 TeV for a full CLIC programme spanning 22 years. For the first stage, an alternative to the CLIC drive beam scheme is presented in which the main linac power is produced using X-band klystrons., Comment: 57 pages, 27 figures, 12 tables, published as CERN Yellow Report. Updated version: Minor layout changes for print version

Published
2016
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19. Pseudomerulius curtisii (Basidiomycota, Boletales, Tapinellaceae) en Argentina y Paraguay

Author

Alex E. Somrau, Barbara R. de Madrignac, Natalia A. Ramirez, Michele G. Campi, and Nicolas Niveiro

Subjects
Pino, timbó, hongo saprófito, Plant culture, SB1-1110, Botany, QK1-989
Abstract

Pseudomerulius curtisii es una especie ampliamente distribuida alrededor del mundo encontrándose citada para Norteamérica, Asia, Oceanía y en Sudamérica en Brasil, siendo una especie introducida en la mayoría de estas regiones al estar estrechamente asociada a plantaciones de pino como saprofita de los mismos. Se caracteriza por presentar un basidioma efuso-reflejo tendiendo a demediado cuando crece, un pileo pubecente con una coloracion amarillo grisáceo a amarillo marrón al madurar e himenóforo merulioide amarillo a marrón rojizo segun la madurez y el contenido de humedad, exhibiendo esporas amarillentas cilíndricas a elipsoidales. El sistema hifal es monomítico conformado por hifas sinuosas, ramificadas con fíbulas ampuliformes. En este trabajo, la describimos e ilustramos en base a colecciones realizadas entre 2015 y 2022 en el nordeste de Argentina y Paraguay.

Published
2022
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25. Abortion Surveillance — United States, 2021

Author

Kortsmit, Katherine, primary, Nguyen, Antoinette T., additional, Mandel, Michele G., additional, Hollier, Lisa M., additional, Ramer, Stephanie, additional, Rodenhizer, Jessica, additional, and Whiteman, Maura K., additional

Published
2023
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30. List of contributors

Author

Acquah, Caleb, primary, Aguiló-Aguayo, Ingrid, additional, Barreira, Luísa, additional, Benavente-Valdés, Juan Roberto, additional, Bernaerts, Tom M.M., additional, Brunton, Nigel, additional, Carreón-González, Berinka Araceli, additional, Chentir, Imene, additional, Costa, Jorge A.V., additional, Costa, Margarida, additional, Edwards, Christine, additional, Ekezie, Flora-Glad, additional, Esteves, Ana F., additional, Ferreira, Alice, additional, Gangadhar, Katkam N., additional, García-Vaquero, Marco, additional, Gonçalves, Ana L., additional, Gouveia, Luisa, additional, Guerra, Inês, additional, Guieysse, Benoit, additional, Hernández-López, Israel, additional, Lafarga, Tomás, additional, Maia, Inês, additional, Markou, Giorgos, additional, Martin, Gregory, additional, Masojidek, J., additional, Medina-Antillón, Alan Eduardo, additional, Méndez-Zavala, Alejandro, additional, Montañez-Saénz, Julio César, additional, Morais, Etiele G., additional, Morais, Michele G., additional, Morales-Oyervides, Lourdes, additional, Muñoz, Dolores Camacho, additional, Palmer, Joseph Samuel, additional, Pereira, Hugo, additional, Pires, José C.M., additional, Plouviez, Maxence, additional, Rajauria, Gaurav, additional, Ranglova, K., additional, Ravindran, Rajeev, additional, Rodríguez-Roque, María Janeth, additional, Salas-Salazar, Nora Aideé, additional, Sánchez-Vega, Rogelio, additional, Schüler, Lisa, additional, Silva, Joana, additional, Silva Benavides, A.M., additional, Soto-Caballero, Mayra Cristina, additional, Torzillo, Giuseppe, additional, Tzovenis, Ioannis, additional, Udenigwe, Chibuike C., additional, Valdivia-Nájar, Carlos Guillermo, additional, Van Loey, Ann M., additional, Varela, João, additional, Velázquez-Arellano, María Elena, additional, Villaró, Silvia, additional, Viñas, Inmaculada, additional, Yatipanthalawa, Bhagya, additional, and Zittelli, G. Chini, additional

Published
2021
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31. Microalgae as source of edible lipids

Author

Morais, Etiele G., primary, Schüler, Lisa, additional, Pereira, Hugo, additional, Maia, Inês, additional, Gangadhar, Katkam N., additional, Costa, Jorge A.V., additional, Morais, Michele G., additional, Varela, João, additional, and Barreira, Luísa, additional

Published
2021
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34. Break-induced replication underlies formation of inverted triplications and generates unexpected diversity in haplotype structures

Author

Grochowski, Christopher M., primary, Bengtsson, Jesse D., additional, Du, Haowei, additional, Gandhi, Mira, additional, Lun, Ming Yin, additional, Mehaffey, Michele G., additional, Park, KyungHee, additional, Höps, Wolfram, additional, Benito-Garagorri, Eva, additional, Hasenfeld, Patrick, additional, Korbel, Jan O., additional, Mahmoud, Medhat, additional, Paulin, Luis F., additional, Jhangiani, Shalini N., additional, Muzny, Donna M., additional, Fatih, Jawid M., additional, Gibbs, Richard A., additional, Pendleton, Matthew, additional, Harrington, Eoghan, additional, Juul, Sissel, additional, Lindstrand, Anna, additional, Sedlazeck, Fritz J., additional, Pehlivan, Davut, additional, Lupski, James R., additional, and Carvalho, Claudia M.B., additional

Published
2023
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39. Focusing on Focus Group Use in Educational Research.

Author

Jarrell, Michele G.

Abstract

This paper gives a brief overview of the focus group method, its history, and usefulness for educational researchers and outlines the essential steps to a successful focus group. An example of the use of focus groups is given. The focus group originated in the 1920s in the social sciences, developed further in market research, and is undergoing a resurgence in the social sciences. The approach has evolved to become useful in educational research. In setting up focus groups, these issues are important: (1) purpose; (2) number of groups; (3) length of group; (4) moderator's guide; (5) moderator; (6) location and setup; (7) participants; (8) number of participants; (9) conducting the group; and (10) analyzing the data. Among the advantages to focus groups is the promotion of interactive discussion among stakeholders. A major disadvantage is data analysis, which can be tedious and difficult. A study of the instructional validity of a state's graduation examination illustrates the use of teacher and student focus groups. When evaluating programs, educational researchers should consider the use of focus groups during and after the implementation of the program as an excellent way to ascertain participants' attitudes. Two appendixes contain sample teachers' and students' group moderator guides. (Contains 34 references.) (SLD)

Published
2000

42. Patient Voice Should Guide Clinical Trial Design for Rare Disease Treatments

Author

Sullivan, Michele G.

Subjects
Homeopathy -- Materia medica and therapeutics, Therapeutics, Clinical trials, Health
Abstract

January 2, 2024 Patient voice is a key ingredient for both sponsors and regulators in developing new therapeutics for rare diseases, according to the FDA. Patient listening sessions are crucial [...]

Published
2024

43. Versatile and Powerful AI Offers Research Assistance Throughout Trial Phases

Author

Sullivan, Michele G.

Subjects
Artificial intelligence -- Research, Natural language interfaces -- Research, Medical colleges -- Research, Computational linguistics -- Research, Language processing -- Research, Machine learning -- Research, Artificial intelligence, Business, Pharmaceuticals and cosmetics industries, Health care industry
Abstract

The clinical trials industry is increasingly turning to artificial intelligence (AI) and machine learning (ML) technologies to boost human performance and productivity and to analyze data in a way that [...]

Published
2023

44. Alzheimer's Trials Need Rethinking to Broaden Participation, Expert Says

Author

Sullivan, Michele G.

Subjects
Alzheimer's disease -- Drug therapy, Health
Abstract

Increasing cultural and ethnic diversity in Alzheimer's clinical trials is a must--but it's going to take a complete rethinking of the way these studies are recruited, conducted, and analyzed, said [...]

Published
2023

45. A Performance Index in a Performance-Based Accreditation System: Year Two.

Author

Jarrell, Michele G.

Abstract

A statewide performance-based accreditation system began using a performance index in 1995-96 to indicate where school districts fall in the distribution of accreditation levels. The purpose of this study was to determine whether there was a significant gain in the performance index in the second year. The performance index was based on the percentage of performance variables met by a district and was designed to assist district personnel in assessing improvement toward higher accreditation levels. District personnel were provided with a table indicating the total number of variables involved in the accreditation system and the performance index assigned for meeting each number. The performance index, used in conjunction with their district scores, indicated to personnel the number of variables on which the district needed improvement and the specific areas requiring improvement. The performance index was assigned in March 1996, and the second index was assigned in March 1997 for 1996-97. An analysis was done to determine if the gain in the 1996-97 performance index was significant over the 1995-96 index for the approximately 150 districts in the state. The difference was found to be significant (p<.01). A flow chart for the accreditation system is provided in an appendix. (Contains two figures, three tables, and seven references.) (Author/SLD)

Published
1997

48. Abortion Surveillance — United States, 2020

Author

Katherine, Kortsmit, Antoinette T, Nguyen, Michele G, Mandel, Elizabeth, Clark, Lisa M, Hollier, Jessica, Rodenhizer, and Maura K, Whiteman

Subjects
Health (social science), Adolescent, Epidemiology, Health, Toxicology and Mutagenesis, Pregnancy, Unplanned, Gestational Age, United States, Health Information Management, Pregnancy, Population Surveillance, Abortion, Legal, District of Columbia, Humans, Female
Abstract

CDC conducts abortion surveillance to document the number and characteristics of women obtaining legal induced abortions and number of abortion-related deaths in the United States.2020.Each year, CDC requests abortion data from the central health agencies for the 50 states, the District of Columbia, and New York City. For 2020, a total of 49 reporting areas voluntarily provided aggregate abortion data to CDC. Of these, 48 reporting areas provided data each year during 2011-2020. Census and natality data were used to calculate abortion rates (number of abortions per 1,000 women aged 15-44 years) and ratios (number of abortions per 1,000 live births), respectively. Abortion-related deaths from 2019 were assessed as part of CDC's Pregnancy Mortality Surveillance System (PMSS).A total of 620,327 abortions for 2020 were reported to CDC from 49 reporting areas. Among 48 reporting areas with data each year during 2011-2020, in 2020, a total of 615,911 abortions were reported, the abortion rate was 11.2 abortions per 1,000 women aged 15-44 years, and the abortion ratio was 198 abortions per 1,000 live births. From 2019 to 2020, the total number of abortions decreased 2% (from 625,346 total abortions), the abortion rate decreased 2% (from 11.4 abortions per 1,000 women aged 15-44 years), and the abortion ratio increased 2% (from 195 abortions per 1,000 live births). From 2011 to 2020, the total number of reported abortions decreased 15% (from 727,554), the abortion rate decreased 18% (from 13.7 abortions per 1,000 women aged 15-44 years), and the abortion ratio decreased 9% (from 217 abortions per 1,000 live births).In 2020, women in their 20s accounted for more than half of abortions (57.2%). Women aged 20-24 and 25-29 years accounted for the highest percentages of abortions (27.9% and 29.3%, respectively) and had the highest abortion rates (19.2 and 19.0 abortions per 1,000 women aged 20-24 and 25-29 years, respectively). By contrast, adolescents aged15 years and women aged ≥40 years accounted for the lowest percentages of abortions (0.2% and 3.7%, respectively) and had the lowest abortion rates (0.4 and 2.6 abortions per 1,000 women aged15 and ≥40 years, respectively). However, abortion ratios were highest among adolescents (aged ≤19 years) and lowest among women aged 25-39 years.Abortion rates decreased from 2011 to 2020 among all age groups. The decrease in abortion rate was highest among adolescents compared with any other age group. From 2019 to 2020, abortion rates decreased or did not change for all age groups. Abortion ratios decreased from 2011 to 2020 for all age groups, except adolescents aged 15-19 years and women aged 25-29 years for whom abortion ratios increased. The decrease in abortion ratio was highest among women aged ≥40 years compared with any other age group. From 2019 to 2020, abortion ratios decreased for adolescents aged15 years and women aged ≥35 and increased for women 15-34 years.In 2020, 80.9% of abortions were performed at ≤9 weeks' gestation, and nearly all (93.1%) were performed at ≤13 weeks' gestation. During 2011-2020, the percentage of abortions performed at13 weeks' gestation remained consistently low (≤9.2%). In 2020, the highest percentage of abortions were performed by early medical abortion at ≤9 weeks' gestation (51.0%), followed by surgical abortion at ≤13 weeks' gestation (40.0%), surgical abortion at13 weeks' gestation (6.7%), and medical abortion at9 weeks' gestation (2.4%); all other methods were uncommon (0.1%). Among those that were eligible (≤9 weeks' gestation), 63.9% of abortions were early medical abortions. In 2019, the most recent year for which PMSS data were reviewed for pregnancy-related deaths, four women died as a result of complications from legal induced abortion.Among the 48 areas that reported data continuously during 2011-2020, overall decreases were observed during 2011-2020 in the total number, rate, and ratio of reported abortions. From 2019 to 2020, decreases also were observed in the total number and rate of reported abortions; however, a 2% increase was observed in the total abortion ratio.Abortion surveillance can be used to help evaluate programs aimed at promoting equitable access to patient-centered quality contraceptive services in the United States to reduce unintended pregnancies.

Published
2022

49. Airway dendritic cell maturation in children exposed to air pollution.

Author

Abigail L Whitehouse, Naseem Mushtaq, Lisa Miyashita, Benjamin Barratt, Ameerah Khan, Harpal Kalsi, Lee Koh, Michele G Padovan, Rossa Brugha, Frances R Balkwill, Andrew J Stagg, and Jonathan Grigg

Subjects
Medicine, Science
Abstract

Urban particulate matter (PM) enhances airway dendritic cell (DC) maturation in vitro. However, to date, there are no data on the association between exposure to urban PM and DC maturation in vivo. We sought to determine whether exposure of school-age children (8 to 14 y) to PM was associated with expression of CD86, a marker of maturation of airway conventional DCs (cDC). Healthy London school children underwent spirometry and sputum induction. Flow cytometry was used to identify CD86 and CCR7 expression on cDC subsets (CD1c+ cDC2 and CD141+ cDC1). Tertiles of mean annual exposure to PM ≤ 10 microns (PM10) at the school address were determined using the London Air Quality Toolkit model. Tertiles of exposure from the 409 children from 19 schools recruited were; lower (23.1 to 25.6 μg/m3, n = 138), middle (25.6 to 26.8 μg/m3, n = 126), and upper (26.8 to 31.0 μg/m3, n = 145). DC expression was assessed in 164/370 (44%) children who completed sputum induction. The proportion (%) of cDC expressing CD86 in the lower exposure tertile (n = 47) was lower compared with the upper exposure tertile (n = 49); (52% (44 to 70%) vs 66% (51 to 82%), p

Published
2020
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50. Educational Research--Past, Present, and Future as Viewed by Graduates of an Educational Research Program.

Author

Jarrell, Michele G.

Abstract

The objectives of this study were to determine the adequacy of the preparation of Educational Research graduates from the University of Alabama, assess their employment history, and solicit opinions concerning the present and future status of Educational Research. A survey instrument mailed to graduates (Ed.S. and Ph.D) from 1973 to the present contained a variety of item formats, and a better than 84 percent return was obtained. Quantitative data were analyzed using primarily frequencies and percentages. Results indicated a change in program emphasis over the past 20 years including increased emphasis on the use of micro- and mainframe computers and an expansion of statistics and measurement offerings. A majority of the respondents secured a position within the first year of graduation and have remained in that position. Most of the graduates conduct research studies in their position. Graduates viewed the research program favorably, and many suggestions for improvement have already been implemented. The future outlook of the respondents included the continued lack of adequate funding for research and an increased need for Educational Researchers whose efforts can be directed at providing information to a variety of agencies to aid in decision-making, and assist and inform groups engaged in educational reform efforts. (Contains 11 references.) (Author)

Published
1993

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