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7 results on '"Michael Guralnick"'

1. Pre-symptomatic intervention for autism spectrum disorder (ASD): defining a research agenda

Author

Rebecca Grzadzinski, Dima Amso, Rebecca Landa, Linda Watson, Michael Guralnick, Lonnie Zwaigenbaum, Gedeon Deák, Annette Estes, Jessica Brian, Kevin Bath, Jed Elison, Leonard Abbeduto, Jason Wolff, and Joseph Piven

Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Abstract Autism spectrum disorder (ASD) impacts an individual’s ability to socialize, communicate, and interact with, and adapt to, the environment. Over the last two decades, research has focused on early identification of ASD with significant progress being made in understanding the early behavioral and biological markers that precede a diagnosis, providing a catalyst for pre-symptomatic identification and intervention. Evidence from preclinical trials suggest that intervention prior to the onset of ASD symptoms may yield more improved developmental outcomes, and clinical studies suggest that the earlier intervention is administered, the better the outcomes. This article brings together a multidisciplinary group of experts to develop a conceptual framework for behavioral intervention, during the pre-symptomatic period prior to the consolidation of symptoms into diagnosis, in infants at very-high-likelihood for developing ASD (VHL-ASD). The overarching goals of this paper are to promote the development of new intervention approaches, empirical research, and policy efforts aimed at VHL-ASD infants during the pre-symptomatic period (i.e., prior to the consolidation of the defining features of ASD).

Published
2021
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3. Predictors of short-term overactive bladder symptom improvement after transurethral resection of prostate in men with benign prostatic obstruction

Author

Yao-Rui, Zhao, Wen-Zhan, Liu, Michael, Guralnick, Wen-Jie, Niu, Yong, Wang, Guang, Sun, and Yong, Xu

Subjects
Aged, 80 and over, Male, Prostatectomy, Urinary Bladder, Overactive, Prostatic Hyperplasia, Urinary Incontinence, Urge, Middle Aged, Severity of Illness Index, Urinary Bladder Neck Obstruction, Urodynamics, Preoperative Period, Humans, Postoperative Period, Prostatism, Aged, Retrospective Studies
Abstract

To investigate the correlation of preoperative overactive bladder symptoms and urodynamic parameters to the improvement of overactive bladder symptoms after transurethral resection of the prostate.A retrospective study was carried out in 128 patients with urodynamically proven benign prostatic obstruction that underwent transurethral resection of the prostate. All patients had preoperative urgency symptoms. The patients were divided into groups according to overactive bladder symptom severity and preoperative urodynamic parameters (presence and type of detrusor overactivity, degree of obstruction, bladder contractility). The 3-month postoperative changes in overactive bladder symptoms were then compared between the groups.Overall, there was a statistically significant improvement in mean overactive bladder symptoms score from 9.6 to 2.7 (P 0.001). However, patients with preoperative mild overactive bladder symptoms had significantly lower postoperative overactive bladder symptoms scores than those with moderate or severe symptoms (P 0.05). Patients with preoperative terminal detrusor overactivity had significantly higher overactive bladder symptoms scores compared with patients with phasic and no detrusor overactivity (P 0.05), and were more likely to have persistent urge incontinence. Preoperative detrusor contractility and severity of obstruction did not affect postoperative overactive bladder symptom improvement.Most patients with benign prostatic obstruction and overactive bladder symptoms experience an improvement in their symptoms after transurethral resection of the prostate. The presence of preoperative terminal detrusor overactivity might be negatively associated with this improvement. The preoperative severity of overactive bladder symptoms, detrusor contractility and degree of bladder outlet obstruction do not appear to have an effect.

Published
2013

4. Combined rectovesicular injuries from low velocity penetrating trauma in an adult

Author

Sreyram, Kuy, Panna A, Codner, Michael, Guralnick, Anahita, Dua, and Jasmeet, Paul

Subjects
Adult, Male, Depression, Rectum, Anal Canal, Humans, Wounds, Stab
Abstract

The most common concomitant site of injury following a penetrating anorectal injury is the genitourinary tract. In anorectal penetrating injuries, other organ injuries must be thoroughly evaluated. In the presence of concomitant rectal and posterior bladder injury, consideration should be given to omental interposition between the surgically repaired organs to prevent fistula formation. Fecal diversion may be required depending upon the integrity of the anal sphincters. Combined rectal and genitourinary trauma from stab wounds or impalement is rare, and requires an interdisciplinary approach utilizing the collaborative expertise of both trauma surgical and urology teams to optimize the intraoperative and postoperative care of the patient.

Published
2013

6. Contributors

Author

Mark C. Adams, David M. Albala, Jennifer T. Anger, Elizabeth Anoia, Dean G. Assimos, Brian K. Auge, Demetrius H. Bagley, Linda A. Baker, Daniel A. Barocas, John M. Barry, Laurence S. Baskin, Stephen Beck, Anthony J. Bella, Jay T. Bishoff, Trinity J. Bivalacqua, Jerry G. Blaivas, Michael L. Blute, Stephen Anthony Boorjian, Joseph Borer, James F. Borin, William O. Brant, John W. Brock, Joshua A. Broghammer, Victor M. Brugh, Jill C. Buckley, Travis L. Bullock, Fiona C. Burkhard, Arthur L. Burnett, Jeffrey A. Cadeddu, Jeffrey B. Campbell, David Canes, Patrick C. Cartwright, Erik P. Castle, Bradley Champagne, Sam S. Chang, Tony Y. Chen, Earl Y. Cheng, Edward Cherullo, Alison M. Christie, Peter E. Clark, Ralph V. Clayman, Michael S. Cookson, Sean T. Corbett, Raymond A. Costabile, Rodney Davis, Leslie A. Deane, Christopher B. Dechet, John O.L. DeLancey, Romano T. DeMarco, John D. Denstedt, Mahesh R. Desai, Mihir M. Desai, Rahul A. Desai, Grant Disick, Roger R. Dmochowski, Jack S. Elder, Sean P. Elliott, Donald A. Elmajian, Amr Fergany, Brian J. Flynn, Lindsay Fossett, Richard Foster, Arvind P. Ganpule, Patricio Gargollo, Inderbir S. Gill, Carl K. Gjertson, David A. Goldfarb, Marc Goldstein, Mark L. Gonzalgo, E. Ann Gormley, Michael Guralnick, Georges-Pascal Haber, George E. Haleblian, David Hartke, Wayne J.G. Hellstrom, S. Duke Herrell, † Frank Hinman, Jeffrey M. Holzbeierlein, Andrew I. Horowitz, William C. Hulbert, Hiroyuki Ihara, Brant Inman, Thomas W. Jarrett, Gerald H. Jordan, Steven A. Kaplan, Melissa R. Kaufman, Louis R. Kavoussi, Stuart Kesler, Phillip S. Kick, Andrew J. Kirsch, Frederick A. Klein, Kathleen C. Kobashi, Philippe Koenig, Chester J. Koh, Paul Kokorowski, Venkatesh Krishnamurthi, Bradley P. Kropp, Ramsay L. Kuo, Jaime Landman, Kindra Larson, Jerilyn M. Latini, Gary E. Leach, David I. Lee, Wendy W. Leng, James O. L’Esperance, Raymond J. Leveillee, David A. Levy, James E. Lingeman, Tom F. Lue, John H. Makari, Eric L. Marderstein, Charles G. Marguet, Frances M. Martin, Jack W. McAninch, R. Dale McClure, Edward J. McGuire, Kevin T. McVary, Robert A. Mevorach, Richard G. Middleton, Douglas F. Milam, Elizabeth A. Miller, Nicole Miller, Joshua K. Modder, Ali Moinzadeh, Manoj Monga, Drogo K. Montague, James Montie, Charles R. Moore, Allen F. Morey, Daniel M. Morgan, Shelby N. Morrisroe, Patrick W. Mufarrij, Ravi Munver, Christopher S. Ng, Alan A. Nisbet, †Andrew C. Novick, R. Corey O’Connor, Zeph Okeke, Raymond W. Pak, Dipen J. Parekh, Margaret S. Pearle, Elise Perer, Andrew C. Peterson, Courtney K. Phillips, Ketsia Pierre, Thomas J. Polascik, Lee Ponsky, John Pope, Glenn M. Preminger, Juan C. Prieto, Ronald Rabinowitz, David E. Rapp, Shlomo Raz, John F. Redman, Lee Richstone, William W. Roberts, Michael J. Rosen, Gregory S. Rosenblatt, Randall G. Rowland, Rajiv Saini, Francisco J.B. Sampaio, Harriette M. Scarpero, Douglas S. Scherr, Peter N. Schlegel, Neil D. Sherman, John Shields, Katsuto Shinohara, Steven W. Siegel, Eila Skinner, Steven J. Skoog, Arthur D. Smith, Joseph A. Smith, Warren T. Snodgrass, Hooman Soltanian, Rene Sotelo, J. Patrick Spirnak, William D. Steers, † John P. Stein, Michael D. Stifelman, Urs E. Studer, Chandru P. Sundaram, Roger L. Sur, Richard W. Sutherland, Kazuo Suzuki, Yeh Hong Tan, Cigdem Tanrikut, David D. Thiel, John C. Thomas, Raju Thomas, Veronica Triaca, Joseph A. Trunzo, Nobuo Tsuru, Paul J. Turek, Christian O. Twiss, Brian A. Vanderbrink, Sandip P. Vasavada, E. Darracott Vaughan, Dennis D. Venable, Srinivas Vourganti, Kristofer R. Wagner, Dena L. Walsh, Thomas J. Walsh, Julian Wan, W. Bedford Waters, George D. Webster, Hunter Wessells, Wesley M. White, John S. Wiener, MD, Geoffrey R. Wignall, Howard N. Winfield, Paul E. Wise, J. Stuart Wolf, Christopher E. Wolter, Michael E. Woods, and Ilia S. Zeltser

Published
2012

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