Search

Herein we describe a method for combining supramolecular catalysis with imininum-based organocatalysis in the Diels-Alder cycloaddition reaction. Both supramolecular host and L-proline are required for the reaction to occur, implying that encapsulation of the substrates and co-catalyst are necessary for the reaction to occur. We explore the substrate scope for a variety of

Organocatalysis inside of a self-assembled supramolecular host provides access to Diels–Alder cyclizations of cinnamaldehydes.