76 results on '"Mezzarobba S."'
Search Results
2. A gait-based paradigm to investigate central body representation in cervical dystonia patients
- Author
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Crisafulli, O, primary, Ravizzotti, E, additional, Mezzarobba, S, additional, Cosentino, C, additional, Bonassi, G, additional, Botta, A, additional, Abbruzzese, G, additional, Marchese, R, additional, Avanzino, L, additional, and Pelosin, E, additional
- Published
- 2022
- Full Text
- View/download PDF
3. Prevalence and associated factors of COVID-19 across Italian regions: a secondary analysis from a national survey on physiotherapists
- Author
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Gambazza, S, Bargeri, S, Campanini, I, Meroni, R, Turolla, A, Castellini, G, Gianola, S, Bertozzi, L, Cattaneo, D, Chiarotto, A, Corbetta, D, Costi, S, Mezzarobba, S, Innocenti, T, Pelosin, E, Petrarca, M, Rossettini, G, Testa, M, Vanti, C, Gambazza S., Bargeri S., Campanini I., Meroni R., Turolla A., Castellini G., Gianola S., Bertozzi L., Cattaneo D., Chiarotto A., Corbetta D., Costi S., Mezzarobba S., Innocenti T., Pelosin E., Petrarca M., Rossettini G., Testa M., Vanti C., Gambazza, S, Bargeri, S, Campanini, I, Meroni, R, Turolla, A, Castellini, G, Gianola, S, Bertozzi, L, Cattaneo, D, Chiarotto, A, Corbetta, D, Costi, S, Mezzarobba, S, Innocenti, T, Pelosin, E, Petrarca, M, Rossettini, G, Testa, M, Vanti, C, Gambazza S., Bargeri S., Campanini I., Meroni R., Turolla A., Castellini G., Gianola S., Bertozzi L., Cattaneo D., Chiarotto A., Corbetta D., Costi S., Mezzarobba S., Innocenti T., Pelosin E., Petrarca M., Rossettini G., Testa M., and Vanti C.
- Abstract
Background: Coronavirus disease 2019 (COVID-19) broke out in China in December 2019 and now is a pandemic all around the world. In Italy, Northern regions were hit the hardest during the first wave. We aim to explore the prevalence and the exposure characteristics of physiotherapists (PTs) working in different Italian regions during the first wave of COVID-19. Methods: Between April and May 2020 a structured anonymous online survey was distributed to all PTs registered in the National Professional Registry to collect prevalence data of a confirmed diagnosis of COVID-19 (i.e., nasopharyngeal swab and/or serological test). A bottom-up agglomerative nesting hierarchical clustering method was applied to identify groups of regions based on response rate. Multivariable logistic regression was used to explore personal and work-related factors associated with a confirmed diagnosis of COVID-19. Results: A total of 15,566 PTs completed the survey (response rate 43.3%). The majority of respondents (57.7%) were from Northern regions. Considering all respondents, the number of confirmed COVID-19 cases in Northern and Central Italy, was higher compared to those in Southern Italy (6.9% vs. 1.8%, P < 0.001); focusing the analysis on respondents who underwent nasopharyngeal swab and/or serological test led to similar findings (14.1% vs. 6.4%, P < 0.001). Working in Northern and Central regions was associated with a higher risk of confirmed diagnosis of COVID-19 compared to Southern regions (OR 3.4, 95%CI 2.6 to 4.3). PTs working in Northern and Central regions were more likely to be reallocated to a different unit and changing job tasks, compared to their colleagues working in the Southern regions (10.5% vs 3.7%, P < 0.001). Conclusions: Work-related risk factors were differently distributed between Italian regions at the time of first pandemic wave, and PTs working in the Northern and Central regions were more at risk of a confirmed diagnosis of COVID-19, especially when w
- Published
- 2021
4. Quantitative Analysis of the Activation Strategies during Freezing in Parkinson’s Patients
- Author
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Accardo, Agostino, Mezzarobba, S., Millevoi, M., Monti, F., Magjarevic, R., editor, Nagel, J. H., editor, Katashev, Alexei, editor, Dekhtyar, Yuri, editor, and Spigulis, Janis, editor
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- 2008
- Full Text
- View/download PDF
5. Prevalence and associated factors of COVID-19 across Italian regions: a secondary analysis from a national survey on physiotherapists
- Author
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Gambazza S., Bargeri S., Campanini I., Meroni R., Turolla A., Castellini G., Gianola S., Bertozzi L., Cattaneo D., Chiarotto A., Corbetta D., Costi S., Mezzarobba S., Innocenti T., Pelosin E., Petrarca M., Rossettini G., Testa M., Vanti C., Gambazza, S, Bargeri, S, Campanini, I, Meroni, R, Turolla, A, Castellini, G, Gianola, S, Bertozzi, L, Cattaneo, D, Chiarotto, A, Corbetta, D, Costi, S, Mezzarobba, S, Innocenti, T, Pelosin, E, Petrarca, M, Rossettini, G, Testa, M, Vanti, C, Gambazza S., Bargeri S., Campanini I., Meroni R., Turolla A., Castellini G., Gianola S., Bertozzi L., Cattaneo D., Chiarotto A., Corbetta D., Costi S., Mezzarobba S., Innocenti T., Pelosin E., Petrarca M., Rossettini G., Testa M., and Vanti C.
- Subjects
Pandemic ,SARS-CoV-2 ,Prevention & control ,Coronaviru ,RZ409.7-999 ,Coronavirus infections ,Coronavirus ,COVID–19 ,Disease outbreaks ,Pandemics ,Physical therapy ,Physiotherapy ,Surveys and questionnaires ,Coronavirus infection ,General Earth and Planetary Sciences ,Surveys and questionnaire ,Prevention & ,Miscellaneous systems and treatments ,Disease outbreak ,control ,Research Article ,General Environmental Science - Abstract
Background Coronavirus disease 2019 (COVID-19) broke out in China in December 2019 and now is a pandemic all around the world. In Italy, Northern regions were hit the hardest during the first wave. We aim to explore the prevalence and the exposure characteristics of physiotherapists (PTs) working in different Italian regions during the first wave of COVID-19. Methods Between April and May 2020 a structured anonymous online survey was distributed to all PTs registered in the National Professional Registry to collect prevalence data of a confirmed diagnosis of COVID-19 (i.e., nasopharyngeal swab and/or serological test). A bottom-up agglomerative nesting hierarchical clustering method was applied to identify groups of regions based on response rate. Multivariable logistic regression was used to explore personal and work-related factors associated with a confirmed diagnosis of COVID-19. Results A total of 15,566 PTs completed the survey (response rate 43.3%). The majority of respondents (57.7%) were from Northern regions. Considering all respondents, the number of confirmed COVID-19 cases in Northern and Central Italy, was higher compared to those in Southern Italy (6.9% vs. 1.8%, P P P Conclusions Work-related risk factors were differently distributed between Italian regions at the time of first pandemic wave, and PTs working in the Northern and Central regions were more at risk of a confirmed diagnosis of COVID-19, especially when working in hospitals. Preventive and organizational measures should be applied to harmonize physiotherapy services in the national context. Registration https://osf.io/x7cha
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- 2021
6. Correlation between Quality of Life and severity of Parkinson's Disease by assessing an optimal cut-off point on the Parkinson's Disease questionnaire (PDQ-39) as related to the Hoehn & Yahr (H&Y) scale
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Galeoto, G, Berardi, A, Colalelli, F, Pelosin, E, Mezzarobba, S, Avanzino, L, Valente, D, Tofani, M, and Fabbrini, G
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Adult ,severity ,Parkinson Disease ,Parkinson ,age ,gender ,quality of life ,Cross-Sectional Studies ,Female ,Humans ,Severity of Illness Index ,Surveys and Questionnaires ,Quality of Life - Abstract
Strong evidence shows that symptoms in individuals with Parkinson's Disease (PD) restrict both their independence and social participation, leading to a low Quality of Life (QoL). Conversely, a reduced QoL has a negative impact on symptoms. The aim is to evaluate the correlation between QoL and severity of PD by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the HoehnYahr (HY) scale in a cohort of Italian adults with PD.A multicenter, cross-sectional study was performed. This study was conducted on a cohort of consecutive individuals. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the HY scale by a neurologist. Receiver op-erating characteristic (ROC) curves and coordinates, visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to HY stages.513 individuals were included in the study. The ROC curve analysis showed that QoL worsened with an increase in disease severity and age. Moreover, QoL was worse in females.The results of this study allowed for the correlation of QoL and disease severity in a cohort of individuals with PD. With this cut-off point, it is now possible to make a determination of QoL of an individual with PD at a certain stage of the disease, in a specific age range, and of a particular gender.
- Published
- 2022
7. Emotional and cognitive information processing in obstacle negotiation in patient with Parkinson’s disease and freezing
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Mezzarobba, S., Grassi, M., Pelosin, E., Manganotti, P., Bernardis, P., Mezzarobba, S., Grassi, M., Pelosin, E., Manganotti, P., and Bernardis, P.
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Emotion ,Freezing of Gait ,obstacle crossing ,Emotions ,Parkinson Disease - Abstract
Objective: We used emotional (images from the International Affective Picture System - IAPS)1 and cognitive inputs (visual perturbation in a stepping-over-the-obstacle task) with the aim to investigate the hypothesis of a cognitive and affective processing overload in the genesis of freezing of gait (FoG) in Parkinson’s disease (PD). Background: FoG is one of the most severe symptoms in PD. It appears as an unpredictable stopping phenomenon during gait and locomo- tor tasks. The underlying mechanism of freezing is still largely unknown. An emerging hypothesis explores freezing as an information processing overload problem produced by a basal ganglia faulty output control in cognitive, limbic and motor neural networks2 Methods: We recruited 12 PD patients with FoG, 11 patients without FoG, and 15 healthy elderly controls. Participants underwent neurological, neuropsychological, and affective state assessments. The emotional stimuli were 20 different images taken from the IAPS system (10 with positive valence, 10 with negative valence, all with a medium level of rating in the arousal). The cognitive stimulus was the obstacle with a light placed on the top. Participants were placed at the beginning of a walkway and were asked to look at a screen placed at the other end, where the IAPS images were presented. The obstacle was positioned in the middle of the walkway (set at 10% of participants’ height). The participants were asked to walk and step over the obstacle, and in half of the trials, when the subject began the last step before overcoming the obstacle, the light on the top was turned on randomly. Results: In PD with FoG, the clearance (vertical distance between the foot and the obstacle during the crossing step) was modulated by the valence of the emotional image when the light was off (lower step clear- ance in response to unpleasant images p=0.020), but not when the light was on. Moreover, results showed slower reaction times in response to unpleas- ant images (p=0.028), and longer times to approach (p=0.012) and cross (p=0.023) the obstacle when unpleasant images were presented. A similar slowing is present in the mean velocity of the crossing step in response to unpleasant images ((p=0.044). Conclusions: Our data support the hypothesis that the increase of cog- nitive and emotional information processing3, could be relevant in the gen- esis of freezing episodes during planning and motor control.
- Published
- 2021
8. Classification of Neurorehabilitation treatments: Preliminary results of a Multicentre Italian Study
- Author
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Bowman, T., Mattos, F. Mestanza, Russo, R., Boninsegna, M., Marazzini, F., Marianelli, A., Pelosin, E., Putzolu, M., Cosentino, C., Maurizio Petrarca, Tirinelli, F., Tondinelli, M., Trecate, F., Budel, M., Turolla, A., Agostini, M., Munari, D., Pillastrini, P., Branchini, M., Lunedei, D., Sgubin, G., Cattaneo, D., Mezzarobba, S., Bowman, T, Mattos, FM, Russo, R, Boninsegna, M, Marazzini, F, Marianelli, A, Pelosin, E, Putzolu, M, Cosentino, C, Petrarca, M, Tirinelli, F, Tondinelli, M, Trecate, F, Budel, M, Turolla, A, Agostini, M, Munari, D, Pillastrini, P, Branchini, M, Lunedei, D, Sgubin, G, Cattaneo, D, and Mezzarobba, S
- Subjects
Clinical Neurology ,Multiple sclerosis (MS) Parkinsonism Rehabilitation - Published
- 2019
9. Correlation between Quality of Life and severity of Parkinson's Disease by assessing an optimal cut-off point on the Parkinson's Disease questionnaire (PDQ-39) as related to the Hoehn & Yahr (H&Y) scale.
- Author
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Galeoto, G., Berardi, A., Colalelli, F., Pelosin, E., Mezzarobba, S., Avanzino, L., Valente, D., Tofani, M., and Fabbrini, G.
- Subjects
PARKINSON'S disease ,QUALITY of life ,SOCIAL participation ,RECEIVER operating characteristic curves ,CROSS-sectional method - Abstract
Purpose. Strong evidence shows that symptoms in individuals with Parkinson's Disease (PD) restrict both their independence and social participation, leading to a low Quality of Life (QoL). Conversely, a reduced QoL has a negative impact on symptoms. The aim is to evaluate the correlation between QoL and severity of PD by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the Hoehn &Yahr (H&Y) scale in a cohort of Italian adults with PD. Methods. A multicenter, cross-sectional study was performed. This study was conducted on a cohort of consecutive individuals. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H&Y scale by a neurologist. Receiver operating characteristic (ROC) curves and coordinates, visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to H&Y stages. Results. 513 individuals were included in the study. The ROC curve analysis showed that QoL worsened with an increase in disease severity and age. Moreover, QoL was worse in females. Conclusions. The results of this study allowed for the correlation of QoL and disease severity in a cohort of individuals with PD. With this cut-off point, it is now possible to make a determination of QoL of an individual with PD at a certain stage of the disease, in a specific age range, and of a particular gender. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
10. Evaluation of Motor Imagery-Based BCI methods in neurorehabilitation of Parkinson’s Disease patients
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Miladinovic, A., primary, Ajcevic, M., additional, Busan, P., additional, Jarmolowska, J., additional, Silveri, G., additional, Deodato, M., additional, Mezzarobba, S., additional, Battaglini, P. P., additional, and Accardo, A., additional
- Published
- 2020
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11. Trattamento riabilitativo e continuità dell'assistenza
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Provinciali, L, Bottini, G, Cappa, S, Ceravolo, MG, Cerri, CG, Coccia, M, Consolmagno, P, Corea, F, Di Bari, M, Flosi, C, Frediani, R, Gandolfi, M, Masotti, G, Mezzarobba, S, Paolucci, S, Pasotti, F, Salina, M, Smania, N, Stramba-Badiale, M, Zampolini, M, Zaninelli, A., Gensini, GF, Zaninelli, A, Provinciali, L, Bottini, G, Cappa, S, Ceravolo, M, Cerri, C, Coccia, M, Consolmagno, P, Corea, F, Di Bari, M, Flosi, C, Frediani, R, Gandolfi, M, Masotti, G, Mezzarobba, S, Paolucci, S, Pasotti, F, Salina, M, Smania, N, Stramba-Badiale, M, and Zampolini, M
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MED/34 - MEDICINA FISICA E RIABILITATIVA ,rehabilitation, stroke - Published
- 2016
12. Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) (2016) Pharmacological and non-pharmacological strategies in the integrated treatment of pain in neurorehabilitation. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation
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Tamburin, S., Lacerenza, M. R., Castelnuovo, Gianluca, Agostini, M., Paolucci, S., Bartolo, M., Bonazza, S., Federico, A., Formaglio, F., Giusti, Emanuele Maria, Manzoni, G. M., Mezzarobba, S., Pietrabissa, Giada, Polli, A., Turolla, A., and Sandrini, G.
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Settore M-PSI/08 - PSICOLOGIA CLINICA ,pain in neurorehabilitation - Published
- 2016
13. Trattamento riabilitativo e continuità dell'assistenza
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Gensini, GF, Zaninelli, A, Provinciali, L, Bottini, G, Cappa, S, Ceravolo, M, Cerri, C, Coccia, M, Consolmagno, P, Corea, F, Di Bari, M, Flosi, C, Frediani, R, Gandolfi, M, Masotti, G, Mezzarobba, S, Paolucci, S, Pasotti, F, Salina, M, Smania, N, Stramba-Badiale, M, Zampolini, M, Ceravolo, MG, Cerri, CG, Zaninelli, A., Gensini, GF, Zaninelli, A, Provinciali, L, Bottini, G, Cappa, S, Ceravolo, M, Cerri, C, Coccia, M, Consolmagno, P, Corea, F, Di Bari, M, Flosi, C, Frediani, R, Gandolfi, M, Masotti, G, Mezzarobba, S, Paolucci, S, Pasotti, F, Salina, M, Smania, N, Stramba-Badiale, M, Zampolini, M, Ceravolo, MG, Cerri, CG, and Zaninelli, A.
- Published
- 2016
14. Time for a Consensus Conference on pain in neurorehabilitation
- Author
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Sandrini, Giorgio, Tamburin, Stefano, Paolucci, Stefano, Boldrini, Paolo, Saraceni, Vincenzo M, Smania, Nicola, Agostini, M, Alfonsi, E, Aloisi, Am, Alvisi, E, Aprile, I, Armando, M, Avenali, M, Azicnuda, E, Barale, F, Bartolo, M, Bergamaschi, R, Berlangieri, M, Berlincioni, V, Berliocchi, L, Berra, E, Berto, G, Bonadiman, S, Bonazza, S, Bressi, F, Brugnera, A, Brunelli, S, Buzzi, Mg, Cacciatori, C, Calvo, A, Cantarella, C, Caraceni, At, Carone, R, Carraro, E, Casale, R, Castellazzi, P, Castelnuovo, G, Castino, A, Cella, M, Cerbo, R, Chiò, A, Ciotti, C, Cisari, C, Coraci, D, Dalla Toffola, E, Defazio, G, De Icco, R, Del Carro, U, Dell’Isola, A, De Tanti, A, D’Ippolito, M, Fazzi, E, Federico, A, Ferrari, A, Ferrari, S, Ferraro, F, Formaglio, F, Formisano, R, Franzoni, S, Gajofatto, F, Gandolfi, M, Gardella, B, Geppetti, P, Giammò, A, Gimigliano, R, Giusti, Em, Greco, E, Ieraci, V, Invernizzi, M, Jacopetti, M, Jedrychowska, I, Lacerenza, M, La Cesa, S, Lobba, D, Magrinelli, F, Mandrini, S, Manera, U, Manzoni, Gm, Marchettini, P, Marchioni, E, Mariotto, S, Martinuzzi, A, Masciullo, M, Mezzarobba, S, Miotti, D, Modenese, A, Molinari, M, Monaco, S, Morone, G, Nappi, R, Negrini, S, Pace, A, Padua, L, Pagliano, E, Palmerini, V, Paolucci, S, Pazzaglia, C, Pecchioli, C, Pietrabissa, G, Picelli, A, Polli, A, Porro, Ca, Porru, D, Romano, M, Roncari, L, Rosa, R, Saccavini, M, Sacerdote, P, Sandrini, G, Saviola, D, Schenone, A, Schweiger, V, Scivoletto, G, Smania, N, Solaro, C, Spallone, V, Springhetti, I, Tamburin, S, Tassorelli, C, Tinazzi, M, Togni, R, Torre, M, Torta, R, Traballesi, M, Trabucco, E, Tramontano, M, Truini, A, Tugnoli, V, Turolla, A, Valeriani, M, Vallies, G, Verzini, E, Vottero, M, Mario, P., Castelnuovo G (ORCID:0000-0003-2633-9822), Giusti EM (ORCID:0000-0001-5767-8785), Padua L (ORCID:0000-0003-2570-9326), Pietrabissa G (ORCID:0000-0002-5911-5748), Sandrini, Giorgio, Tamburin, Stefano, Paolucci, Stefano, Boldrini, Paolo, Saraceni, Vincenzo M, Smania, Nicola, Agostini, M, Alfonsi, E, Aloisi, Am, Alvisi, E, Aprile, I, Armando, M, Avenali, M, Azicnuda, E, Barale, F, Bartolo, M, Bergamaschi, R, Berlangieri, M, Berlincioni, V, Berliocchi, L, Berra, E, Berto, G, Bonadiman, S, Bonazza, S, Bressi, F, Brugnera, A, Brunelli, S, Buzzi, Mg, Cacciatori, C, Calvo, A, Cantarella, C, Caraceni, At, Carone, R, Carraro, E, Casale, R, Castellazzi, P, Castelnuovo, G, Castino, A, Cella, M, Cerbo, R, Chiò, A, Ciotti, C, Cisari, C, Coraci, D, Dalla Toffola, E, Defazio, G, De Icco, R, Del Carro, U, Dell’Isola, A, De Tanti, A, D’Ippolito, M, Fazzi, E, Federico, A, Ferrari, A, Ferrari, S, Ferraro, F, Formaglio, F, Formisano, R, Franzoni, S, Gajofatto, F, Gandolfi, M, Gardella, B, Geppetti, P, Giammò, A, Gimigliano, R, Giusti, Em, Greco, E, Ieraci, V, Invernizzi, M, Jacopetti, M, Jedrychowska, I, Lacerenza, M, La Cesa, S, Lobba, D, Magrinelli, F, Mandrini, S, Manera, U, Manzoni, Gm, Marchettini, P, Marchioni, E, Mariotto, S, Martinuzzi, A, Masciullo, M, Mezzarobba, S, Miotti, D, Modenese, A, Molinari, M, Monaco, S, Morone, G, Nappi, R, Negrini, S, Pace, A, Padua, L, Pagliano, E, Palmerini, V, Paolucci, S, Pazzaglia, C, Pecchioli, C, Pietrabissa, G, Picelli, A, Polli, A, Porro, Ca, Porru, D, Romano, M, Roncari, L, Rosa, R, Saccavini, M, Sacerdote, P, Sandrini, G, Saviola, D, Schenone, A, Schweiger, V, Scivoletto, G, Smania, N, Solaro, C, Spallone, V, Springhetti, I, Tamburin, S, Tassorelli, C, Tinazzi, M, Togni, R, Torre, M, Torta, R, Traballesi, M, Trabucco, E, Tramontano, M, Truini, A, Tugnoli, V, Turolla, A, Valeriani, M, Vallies, G, Verzini, E, Vottero, M, Mario, P., Castelnuovo G (ORCID:0000-0003-2633-9822), Giusti EM (ORCID:0000-0001-5767-8785), Padua L (ORCID:0000-0003-2570-9326), and Pietrabissa G (ORCID:0000-0002-5911-5748)
- Abstract
Time for a Consensus Conference on pain in neurorehabilitation.
- Published
- 2016
15. Optokinetic analysis of gait cycle during walking with 1 cm- and 2 cm-high heel lifts
- Author
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VALENTINI, ROBERTO, MARTINELLI B, MEZZAROBBA S, DE MICHIEL A, TOFFANO M., Valentini, Roberto, Martinelli, B, Mezzarobba, S, DE MICHIEL, A, and Toffano, M.
- Subjects
Optokinetic analysis ,High heel lift ,Gait ,High heel lift, Optokinetic analysis, Gait - Abstract
The use of orthotic heel lifts is proposed in many cases of Achilles tendon disorders as a first-line or conservative treatment. The use of heeled shoes induces a plantar flexion of the ankle joint with a consequent decrease in the tension forces acting onto the triceps surae. The question to address is how high must the heel be? Gait cycle using 1 cm- and 2 cm-high heel lifts was examined. Each measurement included kinetic and kinematic data on angular variation and moments and power at the hip, knee and foot. The study included 14 healthy subjects (5 males, 9 females) between 20 and 35 years of age. The data provided by the analysis of the force plate curve showed a statistically significant change in some parameters (plate forces, knee moments) which were deemed useful in the analysis of load transfer modalities. A very significant decrease (p = 0.0001) was found in the amplitude of the curve expressing the force produced by the whole limb in response to ground reaction forces. This is expressed by a decrease in minimum values, suggesting a lower degree of energy absorption at heel strike, as well as maximum values reflecting the amount of energy generated at push off. This might suggest that by reducing energy absorption by the whole limb a 2-cm heel lift would have a protective effect for those muscles that are most significantly involved in this function, such as the tibiotarsal complex (triceps surae) and the knee complex (rectus femoris).
- Published
- 2009
16. Quantitative sEMG analysis of gait in Parkinson’s patients with freezing in On
- Author
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Monti, Fabrizio, Mezzarobba, S, Accardo, Agostino, Ferigo, L, Millevoi, M, DE MICHIEL, A, Pizzolato, G., Monti, Fabrizio, Mezzarobba, S, Accardo, Agostino, Ferigo, L, Millevoi, M, DE MICHIEL, A, and Pizzolato, G.
- Subjects
Parkinson's disease ,freezing - Published
- 2008
17. A neuropsychological evaluation of freezing in on
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MORETTI, Rita, TORRE P, VILOTTI C, ANTONELLO RM, MEZZAROBBA S, ANTONUTTI L, PIZZOLATO G., Moretti, Rita, Torre, P, Vilotti, C, Antonello, Rm, Mezzarobba, S, Antonutti, L, and Pizzolato, G.
- Published
- 2007
18. UN APPROCCIO NEURO-RIABILITATIVO AL FREEZING NELLA MALATTIA DI PARKINSON
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MEZZAROBBA S, BANDEL D, CAPUS L, TORRE P, MORETTI, Rita, Mezzarobba, S, Bandel, D, Capus, L, Torre, P, and Moretti, Rita
- Published
- 2004
19. Baropodometric examination of patients with diabetic neuropathy at 2 years follow-up: Identification of kinematic parameters of gait related to neuropathy progression
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Valentini, R., primary, Tesser, I., additional, Bortolato, S., additional, Fancellu, G., additional, and Mezzarobba, S., additional
- Published
- 2014
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20. Achilles tendon percutaneous repair with tenolig: Quantitative analysis of postural control and gait pattern
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Mezzarobba, S., primary, Bortolato, S., additional, Giacomazzi, A., additional, Valentini, R., additional, Marcovich, R., additional, and Fancellu, G., additional
- Published
- 2013
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21. Quantitative kinetic and kinematic gait variables after percutaneous achilles tendon repair: Indications for rehabilitation
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Mezzarobba, S., primary, Del Degan, T., additional, Bortolato, S., additional, Giacomazzi, A., additional, Marcovich, R., additional, Fancellu, G., additional, and Valentini, R., additional
- Published
- 2013
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22. Percutaneous repair of Achilles tendon ruptures with Tenolig: Quantitative analysis of postural control and gait pattern
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Mezzarobba, S., primary, Bortolato, S., additional, Giacomazzi, A., additional, Fancellu, G., additional, Marcovich, R., additional, and Valentini, R., additional
- Published
- 2012
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- View/download PDF
23. Optokinetic analysis of gait cycle during walking with 1cm- and 2cm-high heel lifts
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Valentini, R., primary, Martinelli, B., additional, Mezzarobba, S., additional, De Michiel, A., additional, and Toffano, M., additional
- Published
- 2009
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24. Dynamic sEMG analysis of gait in Parkinson’s patients with freezing in ON
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Mezzarobba, S., primary, Millevoi, M., additional, Accardo, A., additional, Monti, F., additional, De Michiel, A., additional, and Marcovich, R., additional
- Published
- 2009
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25. Optokinetic gait analysis with heel orthoses
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Toffano, M., primary, Mezzarobba, S., additional, De Michiel, A., additional, Valentini, R., additional, and Martinelli, B., additional
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- 2009
- Full Text
- View/download PDF
26. Optokinetic analysis of gait cycle during walking with 1 cm- and 2 cm-high heel lifts.
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Valentini R, Martinelli B, Mezzarobba S, De Michiel A, and Toffano M
- Abstract
The use of orthotic heel lifts is proposed in many cases of Achilles tendon disorders as a first-line or conservative treatment. The use of heeled shoes induces a plantar flexion of the ankle joint with a consequent decrease in the tension forces acting onto the triceps surae. The question to address is how high must the heel be? Gait cycle using 1 cm- and 2 cm-high heel lifts was examined. Each measurement included kinetic and kinematic data on angular variation and moments and power at the hip, knee and foot. The study included 14 healthy subjects (5 males, 9 females) between 20 and 35 years of age. The data provided by the analysis of the force plate curve showed a statistically significant change in some parameters (plate forces, knee moments) which were deemed useful in the analysis of load transfer modalities. A very significant decrease (p = 0.0001) was found in the amplitude of the curve expressing the force produced by the whole limb in response to ground reaction forces. This is expressed by a decrease in minimum values, suggesting a lower degree of energy absorption at heel strike, as well as maximum values reflecting the amount of energy generated at push off. This might suggest that by reducing energy absorption by the whole limb a 2-cm heel lift would have a protective effect for those muscles that are most significantly involved in this function, such as the tibiotarsal complex (triceps surae) and the knee complex (rectus femoris). [ABSTRACT FROM AUTHOR]
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- 2009
- Full Text
- View/download PDF
27. Time for a consensus conference on pain in neurorehabilitation
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Sandrini, G, Tamburin, S, Paolucci, S, Boldrini, P, Saraceni, V, Smania, N, Italian Consensus Conference on Pain in Neurorehabilitation, Agostini, M, Alfonsi, E, Aloisi, A, Alvisi, E, Aprile, I, Armando, M, Avenali, M, Azicnuda, E, Barale, F, Bartolo, M, Bergamaschi, R, Berlangieri, M, Berlincioni, V, Berliocchi, L, Berra, E, Berto, G, Bonadiman, S, Bonazza, S, Bressi, F, Brugnera, A, Brunelli, S, Buzzi, M, Cacciatori, C, Calvo, A, Cantarella, C, Caraceni, A, Carone, R, Carraro, E, Casale, R, Castellazzi, P, Castelnuovo, G, Castino, A, Cella, M, Cerbo, R, Chiò, A, Ciotti, C, Cisari, C, Coraci, D, Dalla Toffola, E, Defazio, G, De Icco, R, Del Carro, U, Dell’Isola, A, De Tanti, A, D’Ippolito, M, Fazzi, E, Federico, A, Ferrari, A, Ferrari, S, Ferraro, F, Formaglio, F, Formisano, R, Franzoni, S, Gajofatto, F, Gandolfi, M, Gardella, B, Geppetti, P, Giammò, A, Gimigliano, R, Giusti, E, Greco, E, Ieraci, V, Invernizzi, M, Jacopetti, M, Jedrychowska, I, Lacerenza, M, La Cesa, S, Lobba, D, Magrinelli, F, Mandrini, S, Manera, U, Manzoni, G, Marchettini, P, Marchioni, E, Mariotto, S, Martinuzzi, A, Masciullo, M, Mezzarobba, S, Miotti, D, Modenese, A, Molinari, M, Monaco, S, Morone, G, Nappi, R, Negrini, S, Pace, A, Padua, L, Pagliano, E, Palmerini, V, Pazzaglia, C, Pecchioli, C, Pietrabissa, G, Picelli, A, Polli, A, Porro, C, Porru, D, Romano, M, Roncari, L, Rosa, R, Saccavini, M, Sacerdote, P, Saviola, D, Schenone, A, Schweiger, V, Scivoletto, G, Solaro, C, Spallone, V, Springhetti, I, Tassorelli, C, Tinazzi, M, Togni, R, Torre, M, Torta, R, Traballesi, M, Trabucco, E, Tramontano, M, Truini, A, Tugnoli, V, Turolla, A, Valeriani, M, Vallies, G, Verzini, E, Vottero, M, Mario, P, Sandrini, Giorgio, Tamburin, Stefano, Paolucci, Stefano, Boldrini, Paolo, Saraceni, Vincenzo M., Smania, Nicola, Agostini, Michela, Alfonsi, Enrico, Aloisi, Anna Maria, Alvisi, Elena, Aprile, Irene, Armando, Michela, Avenali, Micol, Azicnuda, Eva, Barale, Francesco, Bartolo, Michelangelo, Bergamaschi, Roberto, Berlangieri, Mariangela, Berlincioni, Vanna, Berliocchi, Laura, Berra, Eliana, Berto, Giulia, Bonadiman, Silvia, Bonazza, Sara, Bressi, Federica, Brugnera, Annalisa, Brunelli, Stefano, Buzzi, Maria Gabriella, Cacciatori, Carlo, Calvo, Andrea, Cantarella, Cristina, Caraceni, Augusto Tommaso, Carone, Roberto, Carraro, Elena, Casale, Roberto, Castellazzi, Paola, Castelnuovo, Gianluca, Castino, Adele, Cella, Monica, Cerbo, Rosanna, Chiò, Adriano, Ciotti, Cristina, Cisari, Carlo, Coraci, Daniele, Toffola, Elena Dalla, Defazio, Giovanni, De Icco, Roberto, Del Carro, Ubaldo, Dell'Isola, Andrea, De Tanti, Antonio, D'Ippolito, Mariagrazia, Fazzi, Elisa, Federico, Angela, Ferrari, Adriano, Ferrari, Sergio, Ferraro, Francesco, Formaglio, Fabio, Formisano, Rita, Franzoni, Simone, Gajofatto, Francesca, Gandolfi, Marialuisa, Gardella, Barbara, Geppetti, Pierangelo, Giammò, Alessandro, Gimigliano, Raffaele, Giusti, Emanuele Maria, Greco, Elena, Ieraci, Valentina, Invernizzi, Marco, Jacopetti, Marco, Jedrychowska, Iwona, Lacerenza, Marco, La Cesa, Silvia, Lobba, Davide, Magrinelli, Francesca, Mandrini, Silvia, Manera, Umberto, Manzoni, Gian Mauro, Marchettini, Paolo, Marchioni, Enrico, Mariotto, Sara, Martinuzzi, Andrea, Masciullo, Marcella, Mezzarobba, Susanna, Miotti, Danilo, Modenese, Angela, Molinari, Marco, Monaco, Salvatore, Morone, Giovanni, Nappi, Rossella, Negrini, Stefano, Pace, Andrea, Padua, Luca, Pagliano, Emanuela, Palmerini, Valerio, Pazzaglia, Costanza, Pecchioli, Cristiano, Pietrabissa, Giada, Picelli, Alessandro, Polli, Andrea, Porro, Carlo Adolfo, Porru, Daniele, Romano, Marcello, Roncari, Laura, Rosa, Riccardo, Saccavini, Marsilio, Sacerdote, Paola, Saviola, Donatella, Schenone, Angelo, Schweiger, Vittorio, Scivoletto, Giorgio, Solaro, Claudio, Spallone, Vincenza, Springhetti, Isabella, Tassorelli, Cristina, Tinazzi, Michele, Togni, Rossella, Torre, Monica, Torta, Riccardo, Traballesi, Marco, Trabucco, Erika, Tramontano, Marco, Truini, Andrea, Tugnoli, Valeria, Turolla, Andrea, Valeriani, Massimiliano, Vallies, Gabriella, Verzini, Elisabetta, Vottero, Mario, and Zerbinati, Paolo
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Male ,peripheral neuropathy ,Time Factors ,Physical Therapy ,consensus conference ,Consensus Development Conferences as Topic ,Sports Therapy and Rehabilitation ,Settore M-PSI/08 - PSICOLOGIA CLINICA ,pain ,diabetic neuropathy ,neurorehabilitation ,neuropathic pain ,Settore MED/13 - Endocrinologia ,Humans ,Pain Management ,Randomized Controlled Trials as Topic ,Physical Therapy, Sports Therapy and Rehabilitation ,Rehabilitation ,Female ,Italy ,Neurological Rehabilitation ,neurorehabilitation, pain, consensus conference ,Settore MED/34 - Medicina Fisica e Riabilitativa ,Settore MED/26 - Neurologia ,Human
28. Freezing of gait is a symptom of Parkinson disease,Un approccio neuro-riabilitativo al 'freezing' nella malattia di Parkinson
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Mezzarobba, S., Bandel, D., Capus, L., Torre, P., and rita moretti
29. EEG changes and motor deficits in Parkinson's disease patients: Correlation of motor scales and EEG power bands
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Joanna Jarmolowska, Miloš Ajčević, Piero Paolo Battaglini, Pierpaolo Busan, Manuela Deodato, Agostino Accardo, Aleksandar Miladinović, Susanna Mezzarobba, Miladinovic, Aleksandar, Ajcevic, M., Busan, P., Jarmolowska, J., Deodato, M., Mezzarobba, S., Battaglini, P. P., and Accardo, Agostino
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Signal Processing (eess.SP) ,medicine.medical_specialty ,Parkinson's disease ,Computer science ,Clinical scales ,Timed Up and Go test ,Electroencephalography ,Audiology ,Clinical scale ,Motor deficit ,Correlation ,Rating scale ,medicine ,FOS: Electrical engineering, electronic engineering, information engineering ,Electrical Engineering and Systems Science - Signal Processing ,EEG signal processing ,Parkinson's Disease ,General Environmental Science ,medicine.diagnostic_test ,Quantitative electroencephalography ,medicine.disease ,Gait ,Quantitative Biology - Neurons and Cognition ,FOS: Biological sciences ,General Earth and Planetary Sciences ,Neurons and Cognition (q-bio.NC) ,Motor Deficit - Abstract
Over the years motor deficit in Parkinson's Disease (PD) patients was largely studied, however, no consistent pattern of relations between quantitative electroencephalography (qEEG) and motor scales emerged. There is a general lack of information on the relation between EEG changes and scales related to specific motor deficits. Therefore, the study aimed to investigate the relation between brain oscillatory activity alterations (EEG power bands) and most used PD-related motor deficit scales. A positive correlation was found between the freezing of the gait questionnaire (FOGQ) and delta spectral power band (rho=0.67; p=0.008), while a negative correlation with the same scale was observed in the alpha spectral power band (rho=-0.59, p=0.027). Additionally, motor scores measure by motor part of Unified Parkinson's Disease Rating Scale (UPDRS) correlated directly with theta (rho=0.55, p=0.040) and inversely with beta EEG power band (rho=-0.77, p=0.001). No significant correlation was found between spectral powers and Hoehn and Yahr (H&Y), BERG (Berg K. et. al. 1995), Modified Parkinson Activity Scale (MPAS), Six-Minute Walk Test (6MWT) and Timed Up and Go Test (TUG). In conclusion, our study supports the earlier findings suggesting a link between EEG slowing and motor decline, providing more insight into the relation between EEG alteration and deficits in different motor domains. These findings indicate that EEG assessment may be a useful biomarker for objective monitoring of progression and neurophysiological effect of rehabilitation approaches in PD's.
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- 2021
30. Evaluation of Motor Imagery-Based BCI methods in neurorehabilitation of Parkinson's Disease patients
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Susanna Mezzarobba, Pierpaolo Busan, Agostino Accardo, Piero Paolo Battaglini, Joanna Jarmolowska, Aleksandar Miladinović, Manuela Deodato, Giulia Silveri, Miloš Ajčević, Miladinovic, Aleksandar, Ajcevic, M., Busan, P., Jarmolowska, J., Silveri, G., Deodato, M., Mezzarobba, S., Battaglini, P. P., and Accardo, A.
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FOS: Computer and information sciences ,medicine.medical_specialty ,Brain-Computer Interface ,Motor-Imagery ,Parkinson's disease ,Computer science ,Common Spatial Filtering ,Computer Science - Human-Computer Interaction ,02 engineering and technology ,Electroencephalography ,Human-Computer Interaction (cs.HC) ,03 medical and health sciences ,0302 clinical medicine ,Motor imagery ,Physical medicine and rehabilitation ,CSP ,0202 electrical engineering, electronic engineering, information engineering ,medicine ,Humans ,BCI ,neurorehabilitation ,Neurorehabilitation ,Brain–computer interface ,medicine.diagnostic_test ,Neurological Rehabilitation ,020206 networking & telecommunications ,Parkinson Disease ,medicine.disease ,Brain-Computer Interfaces ,Imagination ,030217 neurology & neurosurgery - Abstract
The study reports the performance of Parkinson's disease (PD) patients to operate Motor-Imagery based Brain-Computer Interface (MI-BCI) and compares three selected pre-processing and classification approaches. The experiment was conducted on 7 PD patients who performed a total of 14 MI-BCI sessions targeting lower extremities. EEG was recorded during the initial calibration phase of each session, and the specific BCI models were produced by using Spectrally weighted Common Spatial Patterns (SpecCSP), Source Power Comodulation (SPoC) and Filter-Bank Common Spatial Patterns (FBCSP) methods. The results showed that FBCSP outperformed SPoC in terms of accuracy, and both SPoC and SpecCSP in terms of the false-positive ratio. The study also demonstrates that PD patients were capable of operating MI-BCI, although with lower accuracy.
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- 2020
31. Assessment of mobility deficit and treatment efficacy in adhesive capsulitis by measurement of kinematic parameters using IMU sensors
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Luigi Murena, Aleksandar Miladinović, Manuela Deodato, Agostino Accardo, Susanna Mezzarobba, Miloš Ajčević, Ajcevic, M., Deodato, M., Murena, L., Miladinović, A., Mezzarobba, S., and Accardo, A.
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Signal Processing (eess.SP) ,030506 rehabilitation ,medicine.medical_specialty ,shoulder ,medicine.medical_treatment ,adhesive capsuliti ,Kinematics ,IMU sensors ,wearable ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Inertial measurement unit ,FOS: Electrical engineering, electronic engineering, information engineering ,medicine ,In patient ,Electrical Engineering and Systems Science - Signal Processing ,adhesive capsulitis ,kinematic parameters ,IMU sensor ,kinematic parameter ,030222 orthopedics ,Rehabilitation ,business.industry ,Upper body ,medicine.disease ,Treatment efficacy ,Capsulitis ,0305 other medical science ,business ,Range of motion - Abstract
There is a growing research interest towards the use of wireless IMU sensors to assess disability, monitor progress and provide feedback to patients on range of motion and movement performance during upper body rehabilitation. The quality of movement in patients with adhesive capsulitis and relative treatment efficacy has not yet been studied using inertial and magnetic sensors. The aim of this study was to investigate the possibility to quantitatively evaluate capsulate-related deficit versus healthy controls and to assess treatment efficacy by measurement of shoulder kinematic parameters with ISEO protocol using inertial and magnetic measurement system technology. We enrolled 6 patients with adhesive capsulitis (AC) who underwent the experimental assessment by using a set of wireless IMU sensors at the baseline (T0) and after the 15 one- hour individual sessions of physiotherapy (T1). The range of motion in elevation, abduction and the scapulo-humeral rhythm kinematic parameters were extracted from measurements performed in enrolled AC patients and in 7 healthy controls. The results of this preliminary study showed that proposed approach based on measurement of shoulder kinematic parameters with ISEO protocol using IMU wireless sensors can be useful in mobility deficit assessment of patients with adhesive capsulitis, as well as for monitoring of treatment efficacy and its further personalization.
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- 2020
32. Action observation improves sit-to-walk in patients with Parkinson's disease and freezing of gait. Biomechanical analysis of performance
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Mauro Catalan, Lara Stragapede, Björn Krüger, Paolo Manganotti, Lorella Pellegrini, Susanna Mezzarobba, Paolo Bernardis, Michele Grassi, Mezzarobba, S., Grassi, M., Pellegrini, L., Catalan, M., Kruger, B., Stragapede, L., Manganotti, P., and Bernardis, P.
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0301 basic medicine ,Male ,medicine.medical_specialty ,Levodopa ,Parkinson's disease ,medicine.medical_treatment ,Walking ,Motor Activity ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Randomized controlled trial ,Center of pressure (terrestrial locomotion) ,law ,medicine ,Neurologic ,Humans ,Sit to walk ,Gait Disorders ,Sensory cue ,Postural instability ,Gait Disorders, Neurologic ,Aged ,Action observation ,Freezing of gait ,Biomechanical Phenomena ,Female ,Parkinson Disease ,Sitting Position ,Standing Position ,Treatment Outcome ,Visual Perception ,Neurological Rehabilitation ,Rehabilitation ,business.industry ,Cognition ,medicine.disease ,Gait ,030104 developmental biology ,Neurology ,Neurology (clinical) ,Geriatrics and Gerontology ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Introduction Freezing of gait (FoG) is one of the most disabling gait disorders in Parkinson's disease (PD), reflecting motor and cognitive impairments, mainly related to dopamine deficiency. Recent studies investigating kinematic and kinetic factors affecting gait in these patients showed a postural instability characterized by disturbed weight-shifting, inappropriate anticipatory postural adjustment, worse reactive postural control, and a difficulty executing complex motor tasks (i.e. sit-to-walk). These symptoms are difficult to alleviate and not very responsive to Levodopa. For this reason, additional therapeutic actions based on specific therapeutic protocols may help patients with their daily lives. We conducted a randomized control trial aimed to test if two clinical protocols for PD patients with FoG were effective to improve postural control. Methods Rehabilitation protocols, conceived to improve gait, were based on learning motor exercises with the Action Observation plus Sonification (AOS) technique, or by the use of external sensory cues. We collected biomechanical data (Center of Mass COM, Center of Pressure COP, and moving timings), using the sit-to-walk task as a measure of motor and gait performance. Results Kinetic and kinematic data showed that when treatment effects consolidate, patients treated with AOS protocol are more efficient in merging subsequent motor tasks (sit-to-stand and gait initiation), and diminished the total moving time and the area of the COP positions. Conclusion We demonstrated for the first time that PD patients with FoG treated with an AOS protocol aimed at relearning appropriate gait patterns increased balance control and re-acquired more efficient postural control.
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- 2020
33. Postural control deficit during sit-to-walk in patients with Parkinson’s disease and freezing of gait
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Michele Grassi, Roberto Valentini, Paolo Bernardis, Susanna Mezzarobba, Mezzarobba, S., Grassi, M., Valentini, R., and Bernardis, P.
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Male ,medicine.medical_specialty ,Parkinson's disease ,genetic structures ,Movement ,Kinetic analysis ,Biophysics ,Severity of Illness Index ,Postural control ,Discriminant analysis ,Freezing of gait ,Gait initiation ,Prediction ellipsoid ,Sit to walk ,Aged ,Biomechanical Phenomena ,Discriminant Analysis ,Disease Progression ,Female ,Gait ,Gait Disorders, Neurologic ,Humans ,Kinetics ,Middle Aged ,Parkinson Disease ,Postural Balance ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Disease severity ,Neurologic ,Updrs iii ,Medicine ,Orthopedics and Sports Medicine ,Gait Disorders ,Sit to Walk ,Gait Initiation ,Balance (ability) ,Discriminant analysi ,business.industry ,Rehabilitation ,030229 sport sciences ,medicine.disease ,business ,030217 neurology & neurosurgery - Abstract
Introduction The intricate linkage between Freezing of Gait (FoG) and postural control in Parkinson's disease (PD) is unclear. We analyzed the impact of FoG on dynamic postural control. Methods 24 PD patients, 12 with (PD + FoG), 12 without FoG (PD-FoG), and 12 healthy controls, were assessed in ON state. Mobility and postural control were measured with clinical scales (UPDRS III, BBS, MPAS) and with kinematic and kinetic analysis during three tasks, characterized by levels of increasing difficulty to plan sequential movement of postural control: walk (W), gait initiation (GI) and sit-to-walk (STW). Results The groups were balanced by age, disease duration, disease severity, mobility and balance. During STW, the spatial distribution of COP trajectories in PD + FoG patients are spread over medial-lateral space more than in the PD-FoG (p
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- 2018
34. Psychological Considerations in the Assessment and Treatment of Pain in Neurorehabilitation and Psychological Factors Predictive of Therapeutic Response: Evidence and Recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation
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Castelnuovo, Gianluca, Giusti, Emanuele M., Manzoni, Gian Mauro, Saviola, Donatella, Gatti, Arianna, Gabrielli, Samantha, Lacerenza, Marco, Pietrabissa, Giada, Cattivelli, Roberto, Spatola, Chiara A. M., Corti, Stefania, Novelli, Margherita, Villa, Valentina, Cottini, Andrea, Lai, Carlo, Pagnini, Francesco, Castelli, Lorys, Tavola, Mario, Torta, Riccardo, Arreghini, Marco, Zanini, Loredana, Brunani, Amelia, Capodaglio, Paolo, D'aniello, Guido E., Scarpina, Federica, Brioschi, Andrea, Priano, Lorenzo, Mauro, Alessandro, Riva, Giuseppe, Repetto, Claudia, Regalia, Camillo, Molinari, Enrico, Notaro, Paolo, Paolucci, Stefano, Sandrini, Giorgio, Simpson, Susan G., Wiederhold, Brenda, Tamburin, Stefano, Agostini, Michela, Alfonsi, Enrico, Aloisi, Anna Maria, Alvisi, Elena, Aprile, Irene, Armando, Michela, Avenali, Micol, Azicnuda, Eva, Barale, Francesco, Bartolo, Michelangelo, Bergamaschi, Roberto, Berlangieri, Mariangela, Berlincioni, Vanna, Berliocchi, Laura, Berra, Eliana, Berto, Giulia, Bonadiman, Silvia, Bonazza, Sara, Bressi, Federica, Brugnera, Annalisa, Brunelli, Stefano, Buzzi, Maria Gabriella, Cacciatori, Carlo, Calvo, Andrea, Cantarella, Cristina, Caraceni, Augusto, Carone, Roberto, Carraro, Elena, Casale, Roberto, Castellazzi, Paola, Castino, Adele, Cerbo, Rosanna, Chiã², Adriano, Ciotti, Cristina, Cisari, Carlo, Coraci, Daniele, Toffola, Elena Dalla, Defazio, Giovanni, De Icco, Roberto, Del Carro, Ubaldo, Dell'isola, Andrea, De Tanti, Antonio, D'ippolito, Mariagrazia, Fazzi, Elisa, Ferrari, Adriano, Ferrari, Sergio, Ferraro, Francesco, Formaglio, Fabio, Formisano, Rita, Franzoni, Simone, Gajofatto, Francesca, Gandolfi, Marialuisa, Gardella, Barbara, Geppetti, Pierangelo, Giammã², Alessandro, Gimigliano, Raffaele, Greco, Elena, Ieraci, Valentina, Invernizzi, Marco, Jacopetti, Marco, La Cesa, Silvia, Lobba, Davide, Magrinelli, Francesca, Mandrini, Silvia, Manera, Umberto, Marchettini, Paolo, Marchioni, Enrico, Mariotto, Sara, Martinuzzi, Andrea, Masciullo, Marella, Mezzarobba, Susanna, Miotti, Danilo, Modenese, Angela, Molinari, Marco, Monaco, Salvatore, Morone, Giovanni, Nappi, Rossella, Negrini, Stefano, Pace, Andrea, Padua, Luca, Pagliano, Emanuela, Palmerini, Valerio, Pazzaglia, Costanza, Pecchioli, Cristiano, Picelli, Alessandro, Porro, Carlo Adolfo, Porru, Daniele, Romano, Marcello, Roncari, Laura, Rosa, Riccardo, Saccavini, Marsilio, Sacerdote, Paola, Schenone, Angelo, Schweiger, Vittorio, Scivoletto, Giorgio, Smania, Nicola, Solaro, Claudio, Spallone, Vincenza, Springhetti, Isabella, Tassorelli, Cristina, Tinazzi, Michele, Togni, Rossella, Torre, Monica, Traballesi, Marco, Tramontano, Marco, Truini, Andrea, Tugnoli, Valeria, Turolla, Andrea, Vallies, Gabriella, Verzini, Elisabetta, Vottero, Mario, Zerbinati, Paolo, Castelnuovo, Gianluca, Giusti, Emanuele M., Manzoni, Gian Mauro, Saviola, Donatella, Gatti, Arianna, Gabrielli, Samantha, Lacerenza, Marco, Pietrabissa, Giada, Cattivelli, Roberto, Spatola, Chiara A. M., Corti, Stefania, Novelli, Margherita, Villa, Valentina, Cottini, Andrea, Lai, Carlo, Pagnini, Francesco, Castelli, Lory, Tavola, Mario, Torta, Riccardo, Arreghini, Marco, Zanini, Loredana, Brunani, Amelia, Capodaglio, Paolo, D'Aniello, Guido E., Scarpina, Federica, Brioschi, Andrea, Priano, Lorenzo, Mauro, Alessandro, Riva, Giuseppe, Repetto, Claudia, Regalia, Camillo, Molinari, Enrico, Notaro, Paolo, Paolucci, Stefano, Sandrini, Giorgio, Simpson, Susan G., Wiederhold, Brenda, Tamburin, Stefano, Agostini, Michela, Alfonsi, Enrico, Aloisi, Anna Maria, Alvisi, Elena, Aprile, Irene, Armando, Michela, Avenali, Micol, Azicnuda, Eva, Barale, Francesco, Bartolo, Michelangelo, Bergamaschi, Roberto, Berlangieri, Mariangela, Berlincioni, Vanna, Berliocchi, Laura, Berra, Eliana, Berto, Giulia, Bonadiman, Silvia, Bonazza, Sara, Bressi, Federica, Brugnera, Annalisa, Brunelli, Stefano, Buzzi, Maria Gabriella, Cacciatori, Carlo, Calvo, Andrea, Cantarella, Cristina, Caraceni, Augusto, Carone, Roberto, Carraro, Elena, Casale, Roberto, Castellazzi, Paola, Castino, Adele, Cerbo, Rosanna, Chiã², Adriano, Ciotti, Cristina, Cisari, Carlo, Coraci, Daniele, Toffola, Elena Dalla, Defazio, Giovanni, De Icco, Roberto, Del Carro, Ubaldo, Dell'Isola, Andrea, De Tanti, Antonio, D'Ippolito, Mariagrazia, Fazzi, Elisa, Ferrari, Adriano, Ferrari, Sergio, Ferraro, Francesco, Formaglio, Fabio, Formisano, Rita, Franzoni, Simone, Gajofatto, Francesca, Gandolfi, Marialuisa, Gardella, Barbara, Geppetti, Pierangelo, Giammã², Alessandro, Gimigliano, Raffaele, Greco, Elena, Ieraci, Valentina, Invernizzi, Marco, Jacopetti, Marco, La Cesa, Silvia, Lobba, Davide, Magrinelli, Francesca, Mandrini, Silvia, Manera, Umberto, Marchettini, Paolo, Marchioni, Enrico, Mariotto, Sara, Martinuzzi, Andrea, Masciullo, Marella, Mezzarobba, Susanna, Miotti, Danilo, Modenese, Angela, Molinari, Marco, Monaco, Salvatore, Morone, Giovanni, Nappi, Rossella, Negrini, Stefano, Pace, Andrea, Padua, Luca, Pagliano, Emanuela, Palmerini, Valerio, Pazzaglia, Costanza, Pecchioli, Cristiano, Picelli, Alessandro, Porro, Carlo Adolfo, Porru, Daniele, Romano, Marcello, Roncari, Laura, Rosa, Riccardo, Saccavini, Marsilio, Sacerdote, Paola, Schenone, Angelo, Schweiger, Vittorio, Scivoletto, Giorgio, Smania, Nicola, Solaro, Claudio, Spallone, Vincenza, Springhetti, Isabella, Tassorelli, Cristina, Tinazzi, Michele, Togni, Rossella, Torre, Monica, Traballesi, Marco, Tramontano, Marco, Truini, Andrea, Tugnoli, Valeria, Turolla, Andrea, Vallies, Gabriella, Verzini, Elisabetta, Vottero, Mario, Zerbinati, Paolo, Castelnuovo G., Giusti E.M., Manzoni G.M., Saviola D., Gatti A., Gabrielli S., Lacerenza M., Pietrabissa G., Cattivelli R., Spatola C.A.M., Corti S., Novelli M., Villa V., Cottini A., Lai C., Pagnini F., Castelli L., Tavola M., Torta R., Arreghini M., Zanini L., Brunani A., Capodaglio P., D'Aniello G.E., Scarpina F., Brioschi A., Priano L., Mauro A., Riva G., Repetto C., Regalia C., Molinari E., Notaro P., Paolucci S., Sandrini G., Simpson S.G., Wiederhold B., Tamburin S., Agostini M., Alfonsi E., Aloisi A.M., Alvisi E., Aprile I., Armando M., Avenali M., Azicnuda E., Barale F., Bartolo M., Bergamaschi R., Berlangieri M., Berlincioni V., Berliocchi L., Berra E., Berto G., Bonadiman S., Bonazza S., Bressi F., Brugnera A., Brunelli S., Buzzi M.G., Cacciatori C., Calvo A., Cantarella C., Caraceni A., Carone R., Carraro E., Casale R., Castellazzi P., Castino A., Cerbo R., Chio A., Ciotti C., Cisari C., Coraci D., Toffola E.D., Defazio G., De Icco R., Del Carro U., Dell'Isola A., De Tanti A., D'Ippolito M., Fazzi E., Ferrari A., Ferrari S., Ferraro F., Formaglio F., Formisano R., Franzoni S., Gajofatto F., Gandolfi M., Gardella B., Geppetti P., Giammo A., Gimigliano R., Greco E., Ieraci V., Invernizzi M., Jacopetti M., La Cesa S., Lobba D., Magrinelli F., Mandrini S., Manera U., Marchettini P., Marchioni E., Mariotto S., Martinuzzi A., Masciullo M., Mezzarobba S., Miotti D., Modenese A., Molinari M., Monaco S., Morone G., Nappi R., Negrini S., Pace A., Padua L., Pagliano E., Palmerini V., Pazzaglia C., Pecchioli C., Picelli A., Porro C.A., Porru D., Romano M., Roncari L., Rosa R., Saccavini M., Sacerdote P., Schenone A., Schweiger V., Scivoletto G., Smania N., Solaro C., Spallone V., Springhetti I., Tassorelli C., Tinazzi M., Togni R., Torre M., Traballesi M., Tramontano M., Truini A., Tugnoli V., Turolla A., Vallies G., Verzini E., Vottero M., Zerbinati P., Giusti, Emanuele M, and Simpson, Susan G
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medicine.medical_specialty ,lcsh:BF1-990 ,Psychological intervention ,Settore M-PSI/08 - PSICOLOGIA CLINICA ,Review ,03 medical and health sciences ,0302 clinical medicine ,psychological distress ,health psychology ,Chronic pain ,Clinical psychology ,Health psychology ,Neurorehabilitation ,Pain management ,Psychology (all) ,medicine ,Psychology ,psychology (all) ,030212 general & internal medicine ,General Psychology ,neurorehabilitation ,business.industry ,chronic pain ,clinical psychology ,pain management ,medicine.disease ,depression ,pain Treatment ,Settore MED/34 - Medicina Fisica e Riabilitativa ,lcsh:Psychology ,Migraine ,Physical therapy ,Anxiety ,Pain catastrophizing ,medicine.symptom ,business ,Psychosocial ,030217 neurology & neurosurgery ,clinical psychology, health psychology - Abstract
Background: In order to provide effective care to patients suffering from chronic pain secondary to neurological diseases, health professionals must appraise the role of the psychosocial factors in the genesis and maintenance of this condition whilst considering how emotions and cognitions influence the course of treatment. Furthermore, it is important not only to recognize the psychological reactions to pain that are common to the various conditions, but also to evaluate how these syndromes differ with regards to the psychological factors that may be involved. As an extensive evaluation of these factors is still lacking, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) aimed to collate the evidence available across these topics. Objectives: To determine the psychological factors which are associated with or predictive of pain secondary to neurological conditions and to assess the influence of these aspects on the outcome of neurorehabilitation. Methods: Two reviews were performed. In the first, a PUBMED search of the studies assessing the association between psychological factors and pain or the predictive value of these aspects with respect to chronic pain was conducted. The included papers were then rated with regards to their methodological quality and recommendations were made accordingly. In the second study, the same methodology was used to collect the available evidence on the predictive role of psychological factors on the therapeutic response to pain treatments in the setting of neurorehabilitation. Results: The first literature search identified 1170 results and the final database included 189 articles. Factors such as depression, anxiety, pain catastrophizing, coping strategies, and cognitive functions were found to be associated with pain across the various conditions. However, there are differences between chronic musculoskeletal pain, migraine, neuropathy, and conditions associated with complex disability with regards to the psychological aspects that are involved. The second PUBMED search yielded 252 studies, which were all evaluated. Anxiety, depression, pain catastrophizing, coping strategies, and pain beliefs were found to be associated to different degrees with the outcomes of multidisciplinary programs, surgery, physical therapies, and psychological interventions. Finally, sense of presence was found to be related to the effectiveness of virtual reality as a distraction tool. Conclusions: Several psychological factors are associated with pain secondary to neurological conditions and should be acknowledged and addressed in order to effectively treat this condition. These factors also predict the therapeutic response to the neurorehabilitative interventions. Background: In order to provide effective care to patients suffering from chronic pain secondary to neurological diseases, health professionals must appraise the role of the psychosocial factors in the genesis and maintenance of this condition whilst considering how emotions and cognitions influence the course of treatment. Furthermore, it is important not only to recognize the psychological reactions to pain that are common to the various conditions, but also to evaluate how these syndromes differ with regards to the psychological factors that may be involved. As an extensive evaluation of these factors is still lacking, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCPN) aimed to collate the evidence available across these topics. Objectives: To determine the psychological factors which are associated with or predictive of pain secondary to neurological conditions and to assess the influence of these aspects on the outcome of neurorehabilitation. Methods: Two reviews were performed. In the first, a PUBMED search of the studies assessing the association between psychological factors and pain or the predictive value of these aspects with respect to chronic pain was conducted. The included papers were then rated with regards to their methodological quality and recommendations were made accordingly. In the second study, the same methodology was used to collect the available evidence on the predictive role of psychological factors on the therapeutic response to pain treatments in the setting of neurorehabilitation. Results: The first literature search identified 1170 results and the final database included 189 articles. Factors such as depression, anxiety, pain catastrophizing, coping strategies, and cognitive functions were found to be associated with pain across the various conditions. However, there are differences between chronic musculoskeletal pain, migraine, neuropathy, and conditions associated with complex disability with regards to the psychological aspects that are involved. The second PUBMED search yielded 252 studies, which were all evaluated. Anxiety, depression, pain catastrophizing, coping strategies, and pain beliefs were found to be associated to different degrees with the outcomes of multidisciplinary programs, surgery, physical therapies, and psychological interventions. Finally, sense of presence was found to be related to the effectiveness of virtual reality as a distraction tool. Conclusions: Several psychological factors are associated with pain secondary to neurological conditions and should be acknowledged and addressed in order to effectively treat this condition. These factors also predict the therapeutic response to the neurorehabilitative interventions.
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- 2016
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35. Optokinetic gait analysis with heel orthoses
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M. Toffano, Susanna Mezzarobba, A. De Michiel, Roberto Valentini, B Martinelli, Toffano, M, Mezzarobba, S, DE MICHIEL, A, Valentini, Roberto, and Martinelli, B.
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medicine.medical_specialty ,Heel ,medicine.anatomical_structure ,Physical medicine and rehabilitation ,business.industry ,Gait analysis ,Rehabilitation ,Biophysics ,Medicine ,Orthopedics and Sports Medicine ,Optokinetic reflex ,business - Published
- 2008
36. Cerebellar Direct Current Stimulation Reveals the Causal Role of the Cerebellum in Temporal Prediction.
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Terranova S, Botta A, Putzolu M, Bonassi G, Cosentino C, Mezzarobba S, Ravizzotti E, Pelosin E, and Avanzino L
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- Humans, Male, Female, Young Adult, Adult, Anticipation, Psychological physiology, Cerebellum physiology, Transcranial Direct Current Stimulation methods, Time Perception physiology, Reaction Time physiology
- Abstract
Temporal prediction (TP) influences our perception and cognition. The cerebellum could mediate this multi-level ability in a context-dependent manner. We tested whether a modulation of the cerebellar neural activity, induced by transcranial Direct Current Stimulation (tDCS), changed the TP ability according to the temporal features of the context and the duration of target interval. Fifteen healthy participants received anodal, cathodal, and sham tDCS (15 min × 2 mA intensity) over the right cerebellar hemisphere during a TP task. We recorded reaction times (RTs) to a target during the task in two contextual conditions of temporal anticipation: rhythmic (i.e., interstimulus intervals (ISIs) were constant) and single-interval condition (i.e., the estimation of the timing of the target was based on the prior exposure of the train of stimuli). Two ISIs durations were explored: 600 ms (short trials) and 900 ms (long trials). Cathodal tDCS improved the performance during the TP task (shorter RTs) specifically in the rhythmic condition only for the short trials and in the single-interval condition only for the long trials. Our results suggest that the inhibition of cerebellar activity induced a different improvement in the TP ability according to the temporal features of the context. In the rhythmic context, the cerebellum could integrate the temporal estimation with the anticipatory motor responses critically for the short target interval. In the single-interval context, for the long trials, the cerebellum could play a main role in integrating representation of time interval in memory with the elapsed time providing an accurate temporal prediction., (© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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37. Modulation of response times in early-stage Parkinson's disease during emotional processing of embodied and non-embodied stimuli.
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Botta A, Pelosin E, Lagravinese G, Marchese R, Di Biasio F, Bonassi G, Terranova S, Ravizzotti E, Putzolu M, Mezzarobba S, Cosentino C, Avenanti A, and Avanzino L
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- Humans, Male, Female, Aged, Middle Aged, Photic Stimulation, Case-Control Studies, Parkinson Disease psychology, Parkinson Disease physiopathology, Emotions physiology, Reaction Time physiology, Facial Expression
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Valence (positive and negative) and content (embodied vs non-embodied) characteristics of visual stimuli have been shown to influence motor readiness, as tested with response time paradigms. Both embodiment and emotional processing are affected in Parkinson's disease (PD) due to basal ganglia dysfunction. Here we aimed to investigate, using a two-choice response time paradigm, motor readiness when processing embodied (emotional body language [EBL] and emotional facial expressions [FACS]) vs non-embodied (emotional scenes [IAPS]) stimuli with neutral, happy, and fearful content. We enrolled twenty-five patients with early-stage PD and twenty-five age matched healthy participants. Motor response during emotional processing was assessed by measuring response times (RTs) in a home-based, forced two-choice discrimination task where participants were asked to discriminate the emotional stimulus from the neutral one. Rating of valence and arousal was also performed. A clinical and neuropsychological evaluation was performed on PD patients. Results showed that RTs for PD patients were longer for all conditions compared to HC and that RTs were generally longer in both groups for EBL compared to FACS and IAPS, with the sole exception retrieved for PD, where in discriminating fearful stimuli, RTs for EBL were longer compared to FACS but not to IAPS. Furthermore, in PD only, when discriminating fearful respect to neutral stimuli, RTs were shorter when discriminating FACS compared to IAPS. This study shows that PD patients were faster in discriminating fearful embodied stimuli, allowing us to speculate on mechanisms involving an alternative, compensatory, emotional motor pathway for PD patients undergoing fear processing., (© 2024. The Author(s).)
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- 2024
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38. Factors influencing physiotherapy decisions between restorative and compensatory gait rehabilitation: an Italian multicenter study.
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Mestanza Mattos FG, Bowman T, Marazzini F, Salvalaggio S, Allera Longo C, Bocini S, Bonci V, Materazzi FG, Pelosin E, Putzolu M, Turolla A, Mezzarobba S, and Cattaneo D
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Background and Purpose: This study aimed to investigate the factors that influence physiotherapists' decision in choosing restorative or compensatory rehabilitation during gait training in people with neurological disorders (PwNDs) and the different treatments used in the approaches., Methods: This cross-sectional analysis used the baseline data from an observational cohort study. We analyzed data from 83 PwNDs (65 people after stroke, 5 with multiple sclerosis, and 13 with Parkinson's disease) who underwent at least 10 sessions of physiotherapy (PT) focusing on gait function. Performance was quantified using the modified Dynamic Gait Index (MDGI), three impairment domains of Fugl-Meyer Assessment for lower extremity (mFM-LL), Activities-specific Balance Confidence (ABC), modified Barthel Index (mBI), Mini-Mental State Examination (MMSE), and Motivational Index (MI). Forty-three physiotherapists completed a treatment report form categorizing the rehabilitation approach and specifying treatments used (e.g., resistance training and proprioceptive exercises)., Results: Fifty-six subjects underwent restorative rehabilitation approach. The univariate predictors of restorative approach were being in the subacute phase with a disease onset of less than 180 days, (odds ratio [95%CI]; 3.27[1.19-9.24]), mFM-LL (1.25[1.11-1.44]), MMSE (0.85[0.67-1.00]), and number of sessions (1.03[1-1.01]). The backward stepwise analysis revealed an association between restorative and subacute phase (36.32[4.11-545.50]), mFM-LL (3.11[1.55-9.73]), mBI (1.79[1.08-3.77]), MMSE (0.46[0.25-0.71]), and the interaction between mFM-LL and mBI (0.99[0.98-1.00]). No statistically significant association between treatments used and approach was found ( p = 0.46)., Discussion and Conclusion: The restorative approach was more commonly used to improve gait. The main variables associated with this approach were: being in the subacute phase of the disease, a low level of impairment, and a high level of functional independence at baseline. However, few differences were found between the treatments used for the restorative or compensatory approaches, as similar PT treatments were used for both., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2024 Mestanza Mattos, Bowman, Marazzini, Salvalaggio, Allera Longo, Bocini, Bonci, Materazzi, Pelosin, Putzolu, Turolla, Mezzarobba and Cattaneo.)
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- 2024
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39. Motor imagery ability scores are related to cortical activation during gait imagery.
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Putzolu M, Samogin J, Bonassi G, Cosentino C, Mezzarobba S, Botta A, Avanzino L, Mantini D, Vato A, and Pelosin E
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- Adult, Animals, Humans, Walking, Brain, Cell Membrane, Electroencephalography, Gait, Gastropoda
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Motor imagery (MI) is the mental execution of actions without overt movements that depends on the ability to imagine. We explored whether this ability could be related to the cortical activity of the brain areas involved in the MI network. To this goal, brain activity was recorded using high-density electroencephalography in nineteen healthy adults while visually imagining walking on a straight path. We extracted Event-Related Desynchronizations (ERDs) in the θ, α, and β band, and we measured MI ability via (i) the Kinesthetic and Visual Imagery Questionnaire (KVIQ), (ii) the Vividness of Movement Imagery Questionnaire-2 (VMIQ), and (iii) the Imagery Ability (IA) score. We then used Pearson's and Spearman's coefficients to correlate MI ability scores and average ERD power (avgERD). Positive correlations were identified between VMIQ and avgERD of the middle cingulum in the β band and with avgERD of the left insula, right precentral area, and right middle occipital region in the θ band. Stronger activation of the MI network was related to better scores of MI ability evaluations, supporting the importance of testing MI ability during MI protocols. This result will help to understand MI mechanisms and develop personalized MI treatments for patients with neurological dysfunctions., (© 2024. The Author(s).)
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- 2024
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40. Action Observation and Motor Imagery as a Treatment in Patients with Parkinson's Disease.
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Mezzarobba S, Bonassi G, Avanzino L, and Pelosin E
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- Humans, Physical Therapy Modalities, Motor Activity physiology, Imagination physiology, Parkinson Disease therapy, Parkinson Disease rehabilitation, Parkinson Disease physiopathology, Imagery, Psychotherapy methods
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Action observation (AO) and motor imagery (MI) has emerged as promising tool for physiotherapy intervention in Parkinson's disease (PD). This narrative review summarizes why, how, and when applying AO and MI training in individual with PD. We report the neural underpinning of AO and MI and their effects on motor learning. We examine the characteristics and the current evidence regarding the effectiveness of physiotherapy interventions and we provide suggestions about their implementation with technologies. Neurophysiological data suggest a substantial correct activation of brain networks underlying AO and MI in people with PD, although the occurrence of compensatory mechanisms has been documented. Regarding the efficacy of training, in general evidence indicates that both these techniques improve mobility and functional activities in PD. However, these findings should be interpreted with caution due to variety of the study designs, training characteristics, and the modalities in which AO and MI were applied. Finally, results on long-term effects are still uncertain. Several elements should be considered to optimize the use of AO and MI in clinical setting, such as the selection of the task, the imagery or the video perspectives, the modalities of training. However, a comprehensive individual assessment, including motor and cognitive abilities, is essential to select which between AO and MI suite the best to each PD patients. Much unrealized potential exists for the use AO and MI training to provide personalized intervention aimed at fostering motor learning in both the clinic and home setting.
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- 2024
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41. Classification and Quantification of Physical Therapy Interventions across Multiple Neurological Disorders: An Italian Multicenter Network.
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Bowman T, Mestanza Mattos FG, Salvalaggio S, Marazzini F, Allera Longo C, Bocini S, Gennuso M, Materazzi FG, Pelosin E, Putzolu M, Russo R, Turolla A, Mezzarobba S, and Cattaneo D
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Despite their relevance in neurorehabilitation, physical therapy (PT) goals and interventions are poorly described, compromising a proper understanding of PT effectiveness in everyday clinical practice. Thus, this paper aims to describe the prevalence of PT goals and interventions in people with neurological disorders, along with the participants' clinical features, setting characteristics of the clinical units involved, and PT impact on outcome measures. A multicenter longitudinal observational study involving hospitals and rehabilitation centers across Italy has been conducted. We recruited people with stroke ( n = 119), multiple sclerosis ( n = 48), and Parkinson's disease ( n = 35) who underwent the PT sessions foreseen by the National Healthcare System. Clinical outcomes were administered before and after the intervention, and for each participant the physical therapists completed a semi-structured interview to report the goals and interventions of the PT sessions. Results showed that the most relevant PT goals were related to the ICF activities with "walking" showing the highest prevalence. The most used interventions aimed at improving walking performance, followed by those aimed at improving organ/body system functioning, while interventions targeting the cognitive-affective and educational aspects have been poorly considered. Considering PT effectiveness, 83 participants experienced a clinically significant improvement in the outcome measures assessing gait and balance functions.
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- 2023
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42. Assessment of the psychometric properties of the Italian version of the New Freezing of Gait Questionnaire (NFOG-Q-IT) in people with Parkinson disease: a validity and reliability study.
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Mezzarobba S, Cosentino C, Putzolu M, Panuccio F, Fabbrini G, Valente D, Costi S, Galeoto G, and Pelosin E
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- Humans, Psychometrics, Reproducibility of Results, Severity of Illness Index, Surveys and Questionnaires, Gait, Italy, Parkinson Disease complications, Parkinson Disease diagnosis, Parkinson Disease psychology, Gait Disorders, Neurologic diagnosis, Gait Disorders, Neurologic etiology
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Introduction: Freezing of gait (FOG) in Parkinson's disease (PD) is a challenging clinical symptom to assess, due to its episodic nature. A valid and reliable tool is the New FOG Questionnaire (NFOG-Q) used worldwide to measure FOG symptoms in PD., Objective: The aim of this study was to translate, to culturally adapt, and to test the psychometric characteristics of the Italian version of the NFOG-Q (NFOG-Q-It)., Methods: The translation and cultural adaptation was based on ISPOR TCA guidelines to finalize the 9-item NFOG-Q-It. Internal consistency was assessed in 181 Italian PD native speakers who experienced FOG using Cronbach's alpha. Cross-cultural analysis was tested using the Spearman's correlation between the NFOG-Q-It and the Modified Hoehn-Yahr Scale (M-H&Y). To assess construct validity, correlations among NFOG-Q-It, Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Falls Efficacy Scale-International (FES-I), the 6-min Walking Test (6MWT), the Mini Balance Evaluation System Test (Mini-BESTest) and the Short Physical Performance Battery (SPPB) were investigated., Results: The Italian N-FOGQ had high internal consistency (Cronbach's α = 0.859). Validity analysis showed significant correlations between NFOG-Q-IT total score and M-H&Y scores (r = 0.281 p < 0.001), MDS-UPDRS (r = 0.359 p < 0.001), FES-I (r = 0.230 p = 0.002), Mini BESTest (r = -0.256 p = 0.001) and 6MWT (r = -0.166 p = 0.026). No significant correlations were found with SPPB, MOCA and MMSE., Conclusion: The NFOG-It is a valuable and reliable tool for assessing FOG symptoms, duration and frequency in PD subjects. Results provide the validity of NFOG-Q-It by reproducing and enlarging previous psychometric data., (© 2023. The Author(s).)
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- 2023
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43. How Music Moves Us: Music-induced Emotion Influences Motor Learning.
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Bonassi G, Lagravinese G, Bove M, Bisio A, Botta A, Putzolu M, Cosentino C, Mezzarobba S, Pelosin E, and Avanzino L
- Abstract
Music is an important tool for the induction and regulation of emotion. Although learning a sequential motor behaviour is essential to normal motor function, to our knowledge, the role of music-induced emotion on motor learning has not been explored. Our experiment aimed to determine whether listening to different emotional music could influence motor sequence learning. We focused on two sub-components of motor sequence learning: the acquisition of the order of the elements in the sequence (the "what"), and the ability to carry out the sequence, combining the elements in a single, skilled action (the "how"). Twenty subjects performed a motor sequence-learning task with a digitizing tablet in three different experimental sessions. In each session they executed the task while listening to three different musical pieces, eliciting fearful, pleasant, and neutral mood. Eight targets were presented in a pre-set order and subjects were asked to learn the sequence while moving. Music-induced pleasure had an impact on movement kinematics with onset time and peak velocity decreasing and movement time increasing more with respect to neutral music session. Declarative learning, verbal recall of the sequence order, was improved under emotional manipulation, but only for fear-condition. Results suggest that music-induced emotion can influence both sub-components of motor learning in a different way. Music-induced pleasure may have improved motor components of sequence learning by means of increased striatal dopamine availability whereas music-induced fear may facilitate the recruitment of attentional circuits, thus acting on declarative knowledge of the sequence order., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 IBRO. Published by Elsevier Ltd. All rights reserved.)
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- 2023
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44. One cue does not fit all: A systematic review with meta-analysis of the effectiveness of cueing on freezing of gait in Parkinson's disease.
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Cosentino C, Putzolu M, Mezzarobba S, Cecchella M, Innocenti T, Bonassi G, Botta A, Lagravinese G, Avanzino L, and Pelosin E
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- Humans, Cues, Gait, Walking, Parkinson Disease complications, Gait Disorders, Neurologic etiology
- Abstract
The difficulty in assessing FOG and the variety of existing cues, hamper to determine which cueing modality should be applied and which FOG-related aspect should be targeted to reach personalized treatments for FOG. This systematic review aimed to highlight: i) whether cues could reduce FOG and improve FOG-related gait parameters, ii) which cues are the most effective, iii) whether medication state (ON-OFF) affects cues-related results. Thirty-three repeated measure design studies assessing cueing effectiveness were included and subdivided according to gait tasks (gait initiation, walking, turning) and to the medication state. Main results reveal that: preparatory phase of gait initiation benefit from visual and auditory cues; spatio-temporal parameters (e.g., step and stride length) are improved by visual cues during walking; turning time and step time variability are reduced by applying auditory and visual cues. Some findings on the potential benefits of cueing on FOG and FOG gait-related parameters were found. Questions remain about which are the best behavioral strategies according to FOG features and PD clinical characteristics., Competing Interests: Conflict of interest The Authors have no financial or other conflicts of interest associated with this publication to declare., (Copyright © 2023 Elsevier Ltd. All rights reserved.)
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- 2023
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45. Home-based exercise training by using a smartphone app in patients with Parkinson's disease: a feasibility study.
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Putzolu M, Manzini V, Gambaro M, Cosentino C, Bonassi G, Botta A, Ravizzotti E, Avanzino L, Pelosin E, and Mezzarobba S
- Abstract
Background: Parkinson's disease (PD) patients experience deterioration in mobility with consequent inactivity and worsened health and social status. Physical activity and physiotherapy can improve motor impairments, but several barriers dishearten PD patients to exercise regularly. Home-based approaches (e.g., via mobile apps) and remote monitoring, could help in facing this issue., Objective: This study aimed at testing the feasibility, usability and training effects of a home-based exercise program using a customized version of Parkinson Rehab® application., Methods: Twenty PD subjects participated in a two-month minimally supervised home-based training. Daily session consisted in performing PD-specific exercises plus a walking training. We measured: (i) feasibility (training adherence), usability and satisfaction (via an online survey); (ii) safety; (iii) training effects on PD severity, mobility, cognition, and mood. Evaluations were performed at: baseline, after 1-month of training, at the end of training (T2), and at 1-month follow-up (T3)., Results: Eighteen out of twenty participants completed the study without important adverse events. Participants' adherence was 91% ± 11.8 for exercise and 105.9% ± 30.6 for walking training. Usability and satisfaction survey scored 70.9 ± 7.7 out of 80. Improvements in PD severity, mobility and cognition were found at T2 and maintained at follow-up., Conclusion: The home-based training was feasible, safe and seems to positively act on PD-related symptoms, mobility, and cognition in patients with mild to moderate stage of PD disease. Additionally, the results suggest that the use of a mobile app might increase the amount of daily physical activity in our study population. Remote monitoring and tailored exercise programs appear to be key elements for promoting exercise. Future studies in a large cohort of PD participants at different stages of disease are needed to confirm these findings., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Putzolu, Manzini, Gambaro, Cosentino, Bonassi, Botta, Ravizzotti, Avanzino, Pelosin and Mezzarobba.)
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- 2023
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46. Are Motor Imagery Ability scores related to cortical activity during gait imagery?
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Putzolu M, Samogin J, Bonassi G, Cosentino C, Mezzarobba S, Botta A, Avanzino L, Mantini D, Vato A, and Pelosin E
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Motor imagery (MI) is the mental execution of actions without overt movements that depends on the ability to imagine. We explored whether this ability could be related to the cortical activity of the brain areas involved in the MI network. To this goal, brain activity was recorded using high-density electroencephalography (hdEEG) in nineteen healthy adults while visually imagining walking on a straight path. We extracted Event-Related Desynchronizations (ERDs) in the β band, and we measured MI ability via (i) the Kinesthetic and Visual Imagery Questionnaire (KVIQ), (ii) the Vividness of Movement Imagery Questionnaire-2 (VMIQ), and (iii) the Imagery Ability (IA) score. We then used Pearson's and Spearman's coefficients to correlate MI ability scores and average ERD power ( avgERD ). VMIQ was positively correlated with avgERD of frontal and cingulate areas, whereas IA SCORE was positively correlated with avgERD of left inferior frontal and superior temporal regions. Stronger activation of the MI network was related to better scores of MI ability evaluations, supporting the importance of testing MI ability during MI protocols. This result will help to understand MI mechanisms and develop personalized MI treatments for patients with neurological dysfunctions., Competing Interests: Competing interests: The authors declare no competing interests.
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- 2023
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47. Angry and happy expressions affect forward gait initiation only when task relevant.
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Mirabella G, Grassi M, Mezzarobba S, and Bernardis P
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- Humans, Emotions physiology, Cognition, Gait, Facial Expression, Happiness, Anger physiology
- Abstract
Whole-body movements represent an ecologically valid model for assessing the effect of emotional stimuli valence on approach/avoidance reactions as they entail a change of the physical distance between such stimuli and the self. However, research in this field has provided inconsistent results as the task relevance of the emotional content of the stimuli was not properly controlled, and very often, it is impossible to dissociate the effect of arousal from that of valence. To overcome these limitations, we studied the effect of facial emotional expressions (anger and happiness) on forward gait initiation using an experimental paradigm that allows us to compare the impact of the stimuli emotional content when they are task relevant and when they are not. We found that angry and happy expressions altered forward gait initiation parameters differently only when relevant for ongoing goals. In particular, both the reaction times and the percentages of omission errors increased when the go signal was an angry face compared to when the go signal was a happy face. These results indicate that forward step movements share the same features as reaching arm movements regarding emotional stimuli, that is, facial emotions do not automatically influence behavioral responses. Instead, their effects depend critically on their conscious appraisal. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
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- 2023
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48. Perception of biological motion. No sensitivity differences between patients with Parkinson's disease and healthy observers.
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Mezzarobba S, Grassi M, Galliussi J, Murena L, and Bernardis P
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- Male, Female, Humans, Aged, Gait, Recognition, Psychology, Perception, Parkinson Disease complications
- Abstract
The use of biological motion (BM) stimuli (point-light walkers PLW) may be a novel alternative to improve the clinical impact of Action Observation treatments in Parkinson's Disease, by directing the patient's attentional focus on gait kinematics. However, the recognition of biological motion in Parkinson's patients has thus far been controversial. To evaluate the clinical feasibility of using BM stimuli in Action Observation treatments, we aimed at investigating whether Parkinson's patients in the ON-state condition can identify and use gender-specific cues conveyed by the body structure and by the kinematics of gait of a PLW. 30 Parkinson's patients and 30 healthy elderly observers were tested in a gender identification task with PLW. Parkinson's patients were able to correctly identify the gender of PLW; no differences were found between the two groups of observers. While for both groups, the gender identification task was easier when it required a judgment on a healthy PLW. Lastly, we found that females were more sensitive than males in our identification task. Our study shows that Parkinson's patients in the ON-state condition are able to extract subtle structural and kinematic characteristics from biological motion stimuli, which is favorable to the use of BM in Action Observation treatments.
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- 2023
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49. Correlation between Quality of Life and severity of Parkinson's Disease by assessing an optimal cut-off point on the Parkinson's Disease questionnaire (PDQ-39) as related to the Hoehn & Yahr (H&Y) scale.
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Galeoto G, Berardi A, Colalelli F, Pelosin E, Mezzarobba S, Avanzino L, Valente D, Tofani M, and Fabbrini G
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- Adult, Cross-Sectional Studies, Female, Humans, Severity of Illness Index, Surveys and Questionnaires, Parkinson Disease diagnosis, Quality of Life
- Abstract
Purpose: Strong evidence shows that symptoms in individuals with Parkinson's Disease (PD) restrict both their independence and social participation, leading to a low Quality of Life (QoL). Conversely, a reduced QoL has a negative impact on symptoms. The aim is to evaluate the correlation between QoL and severity of PD by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the Hoehn &Yahr (H&Y) scale in a cohort of Italian adults with PD., Methods: A multicenter, cross-sectional study was performed. This study was conducted on a cohort of consecutive individuals. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H&Y scale by a neurologist. Receiver op-erating characteristic (ROC) curves and coordinates, visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to H&Y stages., Results: 513 individuals were included in the study. The ROC curve analysis showed that QoL worsened with an increase in disease severity and age. Moreover, QoL was worse in females., Conclusions: The results of this study allowed for the correlation of QoL and disease severity in a cohort of individuals with PD. With this cut-off point, it is now possible to make a determination of QoL of an individual with PD at a certain stage of the disease, in a specific age range, and of a particular gender.
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- 2022
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50. Neural oscillations during motor imagery of complex gait: an HdEEG study.
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Putzolu M, Samogin J, Cosentino C, Mezzarobba S, Bonassi G, Lagravinese G, Vato A, Mantini D, Avanzino L, and Pelosin E
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- Brain physiology, Electroencephalography, Humans, Imagination physiology, Walking physiology, Gait physiology, Imagery, Psychotherapy
- Abstract
The aim of this study was to investigate differences between usual and complex gait motor imagery (MI) task in healthy subjects using high-density electroencephalography (hdEEG) with a MI protocol. We characterized the spatial distribution of α- and β-bands oscillations extracted from hdEEG signals recorded during MI of usual walking (UW) and walking by avoiding an obstacle (Dual-Task, DT). We applied a source localization algorithm to brain regions selected from a large cortical-subcortical network, and then we analyzed α and β bands Event-Related Desynchronizations (ERDs). Nineteen healthy subjects visually imagined walking on a path with (DT) and without (UW) obstacles. Results showed in both gait MI tasks, α- and β-band ERDs in a large cortical-subcortical network encompassing mostly frontal and parietal regions. In most of the regions, we found α- and β-band ERDs in the DT compared with the UW condition. Finally, in the β band, significant correlations emerged between ERDs and scores in imagery ability tests. Overall we detected MI gait-related α- and β-band oscillations in cortical and subcortical areas and significant differences between UW and DT MI conditions. A better understanding of gait neural correlates may lead to a better knowledge of pathophysiology of gait disturbances in neurological diseases., (© 2022. The Author(s).)
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- 2022
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