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308 results on '"Meyer JJ"'

1. Keratouveitis from Euphorbia cyparissias exposure is a temporal phenomenon

Author: Fleischman D, Meyer JJ, and Fowler WC
Subjects: Ophthalmology, RE1-994
Abstract: David Fleischman, Jay J Meyer, W Craig FowlerDepartment of Ophthalmology, University of North Carolina Hospitals, Chapel Hill, NC, USAAbstract: We present the case of an 82-year-old woman with severe keratouveitis secondary to exposure to the plant Euphorbia cyparissias during the month of August. Despite copious irrigation of both eyes, she developed a case of Euphorbia keratouveitis that was typical in its course. Exposure to plant sap from this species should be treated much like an alkaline chemical injury as the pH of the ocular surface may be elevated. E. cyparissias should be carefully handled as it may result in keratouveitis, especially in early autumn.Keywords: Euphorbia cyparissias, sap, keratitis, uveitis
Published: 2012

2. Case History of the Installation of a Sanitary Sewer Microtunnel Project

Author: Meyer, JJ, primary and Whitehouse, T, additional
Published: 2000
Full Text: View/download PDF

3. The oculus rift film experience: A case study on understanding films in a head mounted display

Author: Syrett, H, Calvi, L, Van Gisbergen, M.S., Poppe, R, Meyer, JJ, Veltkamp, R, Dastani, M, and Academy for Games & Media
Subjects: 060201 languages & linguistics, Computer science, Oculus rift, Headset, media_common.quotation_subject, 05 social sciences, Optical head-mounted display, 050801 communication & media studies, 06 humanities and the arts, Virtual reality, Narrative comprehension, Comprehension, 0508 media and communications, Feeling, Human–computer interaction, Distraction, 0602 languages and literature, Storytelling, ComputingMilieux_MISCELLANEOUS, Film, media_common
Abstract: The purpose of this research was to determine the level of narrative comprehension in films when watched in a virtual reality headset (Oculus Rift). A 360-degree live-action film was created and was shown to participants after which the level of comprehension of various literary aspects as well as the feeling of distraction and enjoyment were measured using questionnaires and interviews. Revealing how increased freedom to view a movie in virtual reality has an effect on storyline understanding, provided a framework to start a discussion on whether and how to utilize virtual reality as a means for storytelling through films.
Published: 2016

4. Search for supersymmetry in events with photons, bottom quarks, and missing transverse momentum in proton-proton collisions at a centre-of-mass energy of 7 TeV with the ATLAS detector

Author: Aad, G, Abajyan, T, Abbott, B, Abdallah, J, Khalek, SA, Abdelalim, AA, Abdinov, O, Aben, R, Abi, B, Abolins, M, AbouZeid, OS, Abramowicz, H, Abreu, H, Acharya, BS, Adamczyk, L, Adams, DL, Addy, TN, Adelman, J, Adomeit, S, Adragna, P, Adye, T, Aefsky, S, Aguilar-Saavedra, JA, Agustoni, M, Aharrouche, M, Ahlen, SP, Ahles, F, Ahmad, A, Ahsan, M, Aielli, G, Akesson, TPA, Akimoto, G, Akimov, AV, Alam, MA, Albert, J, Albrand, S, Aleksa, M, Aleksandrov, IN, Alessandria, F, Alexa, C, Alexander, G, Alexandre, G, Alexopoulos, T, Alhroob, M, Aliev, M, Alimonti, G, Alison, J, Allbrooke, BMM, Allport, PP, Allwood-Spiers, SE, Almond, J, Aloisio, A, Alon, R, Alonso, A, Alonso, F, Altheimer, A, Gonzalez, BA, Alviggi, MG, Amako, K, Amelung, C, Ammosov, VV, Amor Dos Santos, SP, Amorim, A, Amram, N, Anastopoulos, C, Ancu, LS, Andari, N, Andeen, T, Anders, CF, Anders, G, Anderson, KJ, Andreazza, A, Andrei, V, Andrieux, M-L, Anduaga, XS, Angelidakis, S, Anger, P, Angerami, A, Anghinolfi, F, Anisenkov, A, Anjos, N, Annovi, A, Antonaki, A, Antonelli, M, Antonov, A, Antos, J, Anulli, F, Aoki, M, Aoun, S, Bella, LA, Apolle, R, Arabidze, G, Aracena, L, Arai, Y, Arce, ATH, Arfaoui, S, Arguin, J-F, Argyropoulos, S, Arik, E, Arik, M, Armbruster, AJ, Arnaez, O, Arnal, V, Artamonov, A, Artoni, G, Arutinov, D, Asai, S, Ask, S, Asman, B, Asquith, L, Assamagan, K, Astbury, A, Atkinson, M, Aubert, B, Auge, E, Augsten, K, Aurousseau, M, Avolio, G, Axen, D, Azuelos, G, Azuma, Y, Baak, MA, Baccaglioni, G, Bacci, C, Bach, AM, Bachacou, H, Bachas, K, Backes, M, Backhaus, M, Mayes, JJB, Badescu, E, Bagnaia, P, Bahinipati, S, Bai, Y, Bailey, DC, Bain, T, Baines, JT, Baker, OK, Baker, MD, Baker, S, Balek, P, Banas, E, Banerjee, P, Banerjee, S, Banfi, D, Bangert, A, Bansal, V, Bansil, HS, Barak, L, Baranov, SP, Galtieri, AB, Barber, T, Barberio, EL, Barberis, D, Barbero, M, Bardin, DY, Barillari, T, Barisonzi, M, Barklow, T, Barlow, N, Barnett, BM, Barnett, RM, Baroncelli, A, Barone, G, Barr, AJ, Barreiro, F, da Costa, JBG, Bartoldus, R, Barton, AE, Bartsch, V, Basye, A, Bates, RL, Batkova, L, Batley, JR, Battaglia, A, Battistin, M, Bauer, F, Bawa, HS, Beale, S, Beau, T, Beauchemin, PH, Beccherle, R, Bechtle, P, Beck, HP, Becker, K, Becker, S, Beckingham, M, Becks, KH, Beddall, AJ, Beddall, A, Bedikian, S, Bednyakov, VA, Bee, CP, Beemster, LJ, Begel, M, Harpaz, SB, Behera, PK, Beimforde, M, Belanger-Champagne, C, Bell, PJ, Bell, WH, Bella, G, Bellagamba, L, Bellomo, M, Belloni, A, Beloborodova, O, Belotskiy, K, Beltramello, O, Benary, O, Benchekroun, D, Bendtz, K, Benekos, N, Benhammou, Y, Noccioli, EB, Garcia, JAB, Benjamin, DP, Benoit, M, Bensinger, JR, Benslama, K, Bentvelsen, S, Berge, D, Kuutmann, EB, Berger, N, Berghaus, F, Berglund, E, Beringer, J, Bernat, P, Bernhard, R, Bernius, C, Berry, T, Bertella, C, Bertin, A, Bertolucci, F, Besana, MI, Besjes, GJ, Besson, N, Bethke, S, Bhimji, W, Bianchi, RM, Bianchini, L, Bianco, M, Biebel, O, Bieniek, SP, Bierwagen, K, Biesiada, J, Biglietti, M, Bilokon, H, Bindi, M, Binet, S, Bingul, A, Bini, C, Biscarat, C, Bittner, B, Black, CW, Black, KM, Blair, RE, Blanchard, J-B, Blazek, T, Bloch, I, Blocker, C, Blocki, J, Blonde, A, Blum, W, Blumenschein, U, Bobbink, GJ, Bobrovnikov, VS, Bocchetta, SS, Bocci, A, Boddy, CR, Boehler, M, Boek, J, Boek, TT, Boelaert, N, Bogaerts, JA, Bogdanchikov, A, Bogouch, A, Bohm, C, Bohm, J, Boisvert, V, Bold, T, Boldea, V, Bolnet, NM, Bomben, M, Bona, M, Boonekamp, M, Bordoni, S, Borer, C, Borisov, A, Borissov, G, Borjanovic, I, Borri, M, Borroni, S, Bortfeldt, J, Bortolotto, V, Bos, K, Boscherini, D, Bosman, M, Boterenbrood, H, Bouchami, J, Boudreau, J, Bouhova-Thacker, EV, Boumediene, D, Bourdarios, C, Bousson, N, Boveia, A, Boyd, J, Boyko, IR, Bozovic-Jelisavcic, I, Bracinik, J, Branchini, P, Brandt, A, Brandt, G, Brandt, O, Bratzler, U, Brau, B, Brau, JE, Braun, HM, Brazzale, SF, Brelier, B, Bremer, J, Brendlinger, K, Brenner, R, Bressler, S, Bristow, TM, Britton, D, Brochu, FM, Brock, I, Brock, R, Broggi, F, Bromberg, C, Bronner, J, Brooijmans, G, Brooks, T, Brooks, WK, Brown, G, de Renstrom, PAB, Bruncko, D, Bruneliere, R, Brunet, S, Bruni, A, Bruni, G, Bruschi, M, Bryngemark, L, Buanes, T, Buat, Q, Bucci, F, Buchanan, J, Buchholz, P, Buckingham, RM, Buckley, AG, Buda, SI, Budagov, IA, Budick, B, Buescher, V, Bugge, L, Bulekov, O, Bundock, AC, Bunse, M, Buran, T, Burckhart, H, Burdin, S, Burgess, T, Burke, S, Busato, E, Bussey, P, Buszello, CP, Butler, B, Butler, JM, Buttar, CM, Butterworth, JM, Buttinger, W, Byszewski, M, Cabrera Urban, S, Caforio, D, Cakir, O, Calafiura, P, Calderini, G, Calfayan, P, Calkins, R, Caloba, LP, Caloi, R, Calvet, D, Calvet, S, Toro, RC, Camarri, P, Cameron, D, Caminada, LM, Caminal Armadans, R, Campana, S, Campanelli, M, Canale, V, Canelli, F, Canepa, A, Cantero, J, Cantrill, R, Capasso, L, Garrido, MDMC, Caprini, I, Caprini, M, Capriotti, D, Capua, M, Caputo, R, Cardarelli, R, Carli, T, Carlino, G, Carminati, L, Caron, B, Caron, S, Carquin, E, Carrillo-Montoya, GD, Carter, AA, Carter, JR, Carvalho, J, Casadei, D, Casado, MP, Cascella, M, Caso, C, Hernandez, AMC, Castaneda-Miranda, E, Gimenez, VC, Castro, NF, Cataldi, G, Catastini, P, Catinaccio, A, Catmore, JR, Cattai, A, Cattani, G, Caughron, S, Cavaliere, V, Cavalleri, P, Cavalli, D, Cavalli-Sforza, M, Cavasinni, V, Ceradini, F, Cerqueira, AS, Cerri, A, Cerrito, L, Cerutti, F, Cetin, SA, Chafaq, A, Chakraborty, D, Chalupkova, I, Chan, K, Chang, P, Chapleau, B, Chapman, JD, Chapman, JW, Charlton, DG, Chavda, V, Barajas, CAC, Cheatham, S, Chekanov, S, Chekulaev, SV, Chelkov, GA, Chelstowska, MA, Chen, C, Chen, H, Chen, S, Chen, X, Chen, Y, Cheng, Y, Cheplakov, A, El Moursli, RC, Chernyatin, V, Cheu, E, Cheung, SL, Chevalier, L, Chiefari, G, Chikovani, L, Childers, JT, Chilingarov, A, Chiodini, G, Chisholm, AS, Chislett, RT, Chitan, A, Chizhov, MV, Choudalakis, G, Chouridou, S, Christidi, IA, Christov, A, Chromek-Burckhart, D, Chu, ML, Chudoba, J, Ciapetti, G, Ciftci, AK, Ciftci, R, Cinca, D, Cindro, V, Ciocio, A, Cirilli, M, Cirkovic, P, Citron, ZH, Citterio, M, Ciubancan, M, Clark, A, Clark, PJ, Clarke, RN, Cleland, W, Clemens, JC, Clement, B, Clement, C, Coadou, Y, Cobal, M, Coccaro, A, Cochran, J, Coffey, L, Cogan, JG, Coggeshall, J, Colas, J, Cole, S, Colijn, AP, Collins, NJ, Collins-Tooth, C, Collot, J, Colombo, T, Colon, G, Compostella, G, Muino, PC, Coniavitis, E, Conidi, MC, Consonni, SM, Consorti, V, Constantinescu, S, Conta, C, Conti, G, Conventi, F, Cooke, M, Cooper, BD, Cooper-Sarkar, AM, Copic, K, Cornelissen, T, Corradi, M, Corriveau, F, Cortes-Gonzalez, A, Cortiana, G, Costa, G, Costa, MJ, Costanzo, D, Cote, D, Courneyea, L, Cowan, G, Cox, BE, Cranmer, K, Crescioli, F, Cristinziani, M, Crosetti, G, Crepe-Renaudin, S, Cuciuc, C-M, Almenar, CC, Donszelmann, TC, Cummings, J, Curatolo, M, Curtis, CJ, Cuthbert, C, Cwetanski, P, Czirr, H, Czodrowski, P, Czyczula, Z, D'Auria, S, D'Onofrio, M, D'Orazio, A, Da Cunha Sargedas De Sousa, MJ, Da Via, C, Dabrowski, W, Dafinca, A, Dai, T, Dallaire, F, Dallapiccola, C, Dam, M, Dameri, M, Damiani, DS, Danielsson, HO, Dao, V, Darbo, G, Darlea, GL, Dassoulas, JA, Davey, W, Davidek, T, Davidson, N, Davidson, R, Davies, E, Davies, M, Davignon, O, Davison, AR, Davygora, Y, Dawe, E, Dawson, I, Daya-Ishmukhametova, RK, De, K, de Asmundis, R, De Castro, S, De Cecco, S, de Graat, J, De Groot, N, de Jong, P, De la Taille, C, De la Torre, H, De Lorenzi, F, de Mora, L, De Nooij, L, De Pedis, D, De Salvo, A, De Sanctis, U, De Santo, A, De Regie, JBDV, De Zorzi, G, Dearnaley, WJ, Debbe, R, Debenedetti, C, Dechenaux, B, Dedovich, DV, Degenhardt, J, Del Peso, JJ, Del Prete, T, Delemontex, T, Deliyergiyev, M, Dell'Acqua, A, Dell'Asta, L, Della Pietra, M, della Volpe, D, Delmastro, M, Delsart, PA, Deluca, C, Demers, S, Demichev, M, Demirkoz, B, Denisov, SP, Derendarz, D, Derkaoui, JE, Derue, F, Dervan, P, Desch, K, Devetak, E, Deviveiros, PO, Dewhurst, A, DeWilde, B, Dhaliwal, S, Dhullipudi, R, Di Ciaccio, A, Di Ciaccio, L, Di Donato, C, Di Girolamo, A, Di Girolamo, B, Di Luise, S, Di Mattia, A, Di Micco, B, Di Nardo, R, Di Simone, A, Di Sipio, R, Diaz, MA, Diehl, EB, Dietrich, J, Dietzsch, TA, Diglio, S, Yagci, KD, Dingfelder, J, Dinut, F, Dionisi, C, Dita, R, Dita, S, Dittus, F, Djama, F, Djobava, T, do Vale, MAB, Do Valle Wemans, A, Doan, TKO, Dobbs, M, Dobos, D, Dobson, E, Dodd, J, Doglioni, C, Doherty, T, Doi, Y, Dolejsi, J, Dolezal, Z, Dolgoshein, BA, Dohmae, T, Donadelli, M, Donini, J, Dopke, J, Doria, A, Dos Anjos, A, Dotti, A, Dova, MT, Doxiadis, AD, Doyle, AT, Dressnandt, N, Dris, M, Dubbert, J, Dube, S, Duchovni, E, Duckeck, G, Duda, D, Dudarev, A, Dudziak, E, Duehrssen, M, Duerdoth, IP, Duflot, L, Dufour, M-A, Duguid, L, Dunford, M, Yildiz, HD, Duxfield, R, Dwuznik, M, Dueren, M, Ebenstein, WL, Ebke, J, Eckweiler, S, Edson, W, Edwards, CA, Edwards, NC, Ehrenfeld, W, Eifert, T, Eigen, G, Einsweiler, K, Eisenhandler, E, Ekelof, T, El Kacimi, M, Ellert, M, Elles, S, Ellinghaus, F, Ellis, K, Ellis, N, Elmsheuser, J, Elsing, M, Emeliyanov, D, Engelmann, R, Engl, A, Epp, B, Erdmann, J, Ereditato, A, Eriksson, D, Ernst, J, Ernst, M, Ernwein, J, Errede, D, Errede, S, Ertel, E, Escalier, M, Esch, H, Escobar, C, Espinal Curull, X, Esposito, B, Etienne, F, Etienvre, AI, Etzion, E, Evangelakou, D, Evans, H, Fabbri, L, Fabre, C, Fakhrutdinov, RM, Falciano, S, Fang, Y, Fanti, M, Farbin, A, Farilla, A, Farley, J, Farooque, T, Farrell, S, Farrington, SM, Farthouat, P, Fassi, F, Fassnacht, P, Fassouliotis, D, Fatholahzadeh, B, Favareto, A, Fayard, L, Federic, P, Fedin, OL, Fedorko, W, Fehling-Kaschek, M, Feligioni, L, Feng, C, Feng, EJ, Fenyuk, AB, Ferencei, J, Fernando, W, Ferrag, S, Ferrando, J, Ferrara, V, Ferrari, A, Ferrari, P, Ferrari, R, de Lima, DEF, Ferrer, A, Ferrere, D, Ferretti, C, Parodi, AF, Fiascaris, M, Fiedler, F, Filipcic, A, Filthaut, F, Fincke-Keeler, M, Fiolhais, MCN, Fiorini, L, Firan, A, Fischer, G, Fisher, MJ, Flechl, M, Fleck, I, Fleckner, J, Fleischmann, P, Fleischmann, S, Flick, T, Floderus, A, Castillo, LRF, Bustos, ACF, Flowerdew, MJ, Martin, TF, Formica, A, Forti, A, Fortin, D, Fournier, D, Fowler, AJ, Fox, H, Francavilla, P, Franchini, M, Franchino, S, Francis, D, Frank, T, Franklin, M, Franz, S, Fraternali, M, Fratina, S, French, ST, Friedrich, C, Friedrich, F, Froidevaux, D, Frost, JA, Fukunaga, C, Torregrosa, EF, Fulsom, BG, Fuster, J, Gabaldon, C, Gabizon, O, Gadfort, T, Gadomski, S, Gagliardi, G, Gagnon, R, Galea, C, Galhardo, B, Gallas, EJ, Gallo, V, Gallop, BJ, Gallus, P, Gan, KK, Gao, YS, Gaponenko, A, Garberson, E, Garcia-Sciveres, M, Garcia, C, Garcia Navarro, JE, Gardner, RW, Garelli, N, Garitaonandia, H, Garonne, V, Gatti, C, Gaudio, G, Gaur, B, Gauthier, L, Gauzzi, P, Gavrilenko, IL, Gay, C, Gaycken, G, Gazis, EN, Ge, P, Gecse, Z, Gee, CNP, Geerts, DAA, Geich-Gimbel, C, Gellerstedt, K, Gemme, C, Gemmell, A, Genest, MH, Gentile, S, George, M, George, S, Gerbaudo, D, Gerlach, P, Gershon, A, Geweniger, C, Ghazlane, H, Ghodbane, N, Giacobbe, B, Giagu, S, Giangiobbe, V, Gianotti, E, Gibbard, B, Gibson, A, Gibson, SM, Gilchriese, M, Gillberg, D, Gillman, AR, Gingrich, DM, Ginzburg, J, Giokaris, N, Giordani, MP, Giordano, R, Giorgi, FM, Giovannini, P, Giraud, PF, Giugni, D, Giunta, M, Gjelsten, BK, Gladilin, LK, Glasman, C, Glatzer, J, Glazov, A, Glitza, KW, Glonti, GL, Goddard, JR, Godfrey, J, Godlewski, JJ, Goebel, M, Goepfert, T, Goeringer, C, Goessling, C, Goldfarb, S, Golling, T, Golubkov, D, Gomes, A, Fajardo, LSG, Goncalo, R, Da Costa, JGPF, Gonella, L, de la Hoz, SG, Gonzalez Parra, G, Silva, MLG, Gonzalez-Sevilla, S, Goodson, JJ, Goossens, L, Gorbounov, PA, Gordon, HA, Gorelov, I, Gorfine, G, Gorini, B, Gorini, E, Gorisek, A, Gornicki, E, Goshaw, AT, Gosselink, M, Gostkin, MI, Eschrich, IG, Gouighri, M, Goujdami, D, Goulette, MP, Goussiou, AG, Goy, C, Gozpinar, S, Grabowska-Bold, I, Grafstroem, P, Grahn, K-J, Gramstad, E, Grancagnolo, F, Grancagnolo, S, Grassi, V, Gratchev, V, Grau, N, Gray, HM, Gray, JA, Graziani, E, Grebenyuk, OG, Greenshaw, T, Greenwood, ZD, Gregersen, K, Gregor, IM, Grenier, P, Griffiths, JJ, Grigalashvili, N, Grillo, AA, Grimm, K, Grinstein, S, Gris, P, Grishkevich, YV, Grivaz, J-F, Grohsjean, A, Gross, E, Grosse-Knetter, J, Groth-Jensen, J, Grybel, K, Guest, D, Guicheney, C, Guido, E, Guindon, S, Gul, U, Gunther, J, Guo, B, Guo, J, Gutierrez, P, Guttman, N, Gutzwiller, O, Guyot, C, Gwenlan, C, Gwilliam, CB, Haas, A, Haas, S, Haber, C, Hadavand, HK, Hadley, DR, Haefner, P, Hahn, F, Hajduk, Z, Hakobyan, H, Hall, D, Hamacher, K, Hamal, P, Hamano, K, Hamer, M, Hamilton, A, Hamilton, S, Han, L, Hanagaki, K, Hanawa, K, Hance, M, Handel, C, Hanke, P, Hansen, JR, Hansen, JB, Hansen, JD, Hansen, PH, Hansson, P, Hara, K, Harenberg, T, Harkusha, S, Harper, D, Harrington, RD, Harris, OM, Hartert, J, Hartjes, F, Haruyama, T, Harvey, A, Hasegawa, S, Hasegawa, Y, Hassani, S, Haug, S, Hauschild, M, Hauser, R, Havranek, M, Hawkes, CM, Hawkings, RJ, Hawkins, AD, Hayakawa, T, Hayashi, T, Hayden, D, Hays, CP, Hayward, HS, Haywood, SJ, Head, SJ, Hedberg, V, Heelan, L, Heim, S, Heinemann, B, Heisterkamp, S, Helary, L, Heller, C, Heller, M, Hellman, S, Hellmich, D, Helsens, C, Henderson, RCW, Henke, M, Henrichs, A, Correia, AMH, Henrot-Versille, S, Hensel, C, Hernandez, CM, Jimenez, YH, Herrberg, R, Herten, G, Hertenberger, R, Hervas, L, Hesketh, GG, Hessey, NP, Higon-Rodriguez, E, Hill, JC, Hiller, KH, Hillert, S, Hillier, SJ, Hinchliffe, I, Hines, E, Hirose, M, Hirsch, F, Hirschbuehl, D, Hobbs, J, Hod, N, Hodgkinson, MC, Hodgson, P, Hoecker, A, Hoeferkamp, MR, Hoffman, J, Hoffmann, D, Hohlfeld, M, Holder, M, Holmgren, SO, Holy, T, Holzbauer, JL, Hong, TM, van Huysduynen, LH, Horner, S, Hostachy, J-Y, Hou, S, Hoummada, A, Howard, J, Howarth, J, Hristova, I, Hrivnac, J, Hryn'ova, T, Hsu, PJ, Hsu, S-C, Hu, D, Hubacek, Z, Hubaut, F, Huegging, F, Huettmann, A, Huffman, TB, Hughes, EW, Hughes, G, 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Teinturier, M, Teischinger, FA, Castanheira, MTD, Teixeira-Dias, P, Temming, KK, Ten Kate, H, Teng, PK, Terada, S, Terashi, K, Terron, J, Testa, M, Teuscher, RJ, Therhaag, J, Theveneaux-Pelzer, T, Thoma, S, Thomas, JP, Thompson, EN, Thompson, PD, Thompson, AS, Thomsen, LA, Thomson, E, Thomson, M, Thong, WM, Thun, RP, Tian, F, Tibbetts, MJ, Tic, T, Tikhomirov, VO, Tikhonovh, YA, Timoshenko, S, Tiouchichine, E, Tipton, R, Tisserant, S, Todorov, T, Todorova-Nova, S, Toggerson, B, Tojo, J, Tokar, S, Tokushuku, K, Tollefson, K, Tomoto, M, Tompkins, L, Toms, K, Tonoyan, A, Topfel, C, Topilin, ND, Torrence, E, Torres, H, Torro Pastor, E, Toth, J, Touchard, E, Tovey, DR, Trefzger, T, Tremblet, L, Tricoli, A, Trigger, IM, Trincaz-Duvoid, S, Tripiana, MF, Triplett, N, Trischuk, W, Trocme, B, Troncon, C, Trottier-McDonald, M, True, P, Trzebinski, M, Trzupek, A, Tsarouchas, C, Tseng, JC-L, Tsiakiris, M, Tsiareshka, PV, Tsionou, D, Tsipolitis, G, Tsiskaridze, S, Tsiskaridze, V, Tskhadadze, EG, Tsukerman, II, Tsulaia, V, Tsung, JW, Tsuno, S, Tsybychev, D, Tua, A, Tudorache, A, Tudorache, V, Tuggle, JM, Turala, M, Turecek, D, Cakir, IT, Turlay, E, Turra, R, Tuts, PM, Tykhonov, A, Tylmad, M, Tyndel, M, Tzanakos, G, Uchida, K, Ueda, I, Ueno, R, Ughetto, M, Ugland, M, Uhlenbrock, M, Uhrmacher, M, Ukegawa, E, Unal, G, Undrus, A, Unel, G, Unno, Y, Urbaniec, D, Urquijo, P, Usai, G, Uslenghi, M, Vacavant, L, Vacek, V, Vachon, B, Vahsen, S, Valentinetti, S, Valero, A, Valkar, S, Valladolid Gallego, E, Vallecorsa, S, Valls Ferrer, JA, Van Berg, R, Van Der Deij, PC, van der Geer, R, van der Graaf, H, Van Der Leeuw, R, van der Poel, E, van der Ster, D, van Eldik, N, van Gemmeren, P, Van Nieuwkoop, J, van Vulpen, I, Vanadia, M, Vandelli, W, Vaniachine, A, Vankov, P, Vannucci, F, Vari, R, Varnes, EW, Varol, T, Varouchas, D, Vartapetian, A, Varvell, KE, Vassilakopoulos, VI, Vazeille, F, Schroeder, TV, Vegni, G, Veillet, JJ, Veloso, F, Veness, R, Veneziano, S, Ventura, A, Ventura, D, Venturi, M, Venturi, N, Vercesi, V, Verducci, M, Verkerke, W, Vermeulen, JC, Vest, A, Vetterli, MC, Vichou, I, Vickey, T, Boeriu, OEV, Viehhauser, GHA, Viel, S, Villa, M, Villaplana Perez, M, Vilucchi, E, Vincter, MG, Vinek, E, Vinogradov, VB, Virchaux, M, Virzi, J, Vitells, O, Viti, M, Vivarelli, I, Vague, FV, Vlachos, S, Vladoiu, D, Vlasak, M, Vogel, A, Vokac, P, Volpi, G, Volpi, M, Volpini, G, von der Schmitt, H, von Radziewski, H, von Toerne, E, Vorobel, V, Vorwerk, V, Vos, M, Voss, R, Vossebeld, JH, Vranjes, N, Milosavljevic, MV, Vrba, V, Vreeswijk, M, Anh, TV, Vuillermet, R, Vukotic, I, Wagner, W, Wagner, P, Wahlen, H, Wahrmund, S, Wakabayashi, J, Walch, S, Walder, J, Walker, R, Walkowiak, W, Wall, R, Waller, P, Walsh, B, Wang, C, Wang, H, Wang, J, Wang, R, Wang, SM, Wang, T, Warburton, A, Ward, CP, Wardrope, DR, Warsinsky, M, Washbrook, A, Wasicki, C, Watanabe, I, Watkins, PM, Watson, AT, Watson, IJ, Watson, MF, Watts, G, Watts, S, Waugh, AT, Waugh, BM, Weber, MS, Webster, JS, Weidberg, AR, Weigell, P, Weingarten, J, Weiser, C, Wells, PS, Wenaus, T, Wendland, D, Weng, Z, Wengler, T, Wenig, S, Wermes, N, Werner, M, Werner, P, Werth, M, Wessels, M, Wetter, J, Weydert, C, Whalen, K, White, A, White, MJ, White, S, Whitehead, SR, Whiteson, D, Whittington, D, Wicke, D, Wickens, FJ, Wiedenmann, W, Wielers, M, Wienemann, P, Wiglesworth, C, Wiik-Fuchs, LAM, Wijeratne, PA, Wildauer, A, Wildt, MA, Wilhelm, I, Wilkens, HG, Will, JZ, Williams, E, Williams, HH, Williams, S, Willis, W, Willocq, S, Wilson, JA, Wilson, MG, Wilson, A, Wingerter-Seez, I, Winkelmann, S, Winklmeier, F, Wittgen, M, Wollstadt, SJ, Wolter, MW, Wolters, H, Wong, WC, Wooden, G, Wosiek, BK, Wotschack, J, Woudstra, MJ, Wozniak, KW, Wraight, K, Wright, M, Wrona, B, Wu, SL, Wu, X, Wu, Y, Wulf, E, Wynne, BM, Xella, S, Xiao, M, Xie, S, Xu, C, Xu, D, Xu, L, Yabsley, B, Yacoob, S, Yamada, M, Yamaguchi, H, Yamamoto, A, Yamamoto, K, Yamamoto, S, Yamamura, T, Yamanaka, T, Yamazaki, T, Yamazaki, Y, Yan, Z, Yang, 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Aad, T. Abajyan, B. Abbott, J. Abdallah, S. Abdel Khalek, A.A. Abdelalim, O. Abdinov, R. Aben, B. Abi, M. Abolin, O.S. AbouZeid, H. Abramowicz, H. Abreu, B.S. Acharya, L. Adamczyk, D.L. Adam, T.N. Addy, J. Adelman, S. Adomeit, P. Adragna, T. Adye, S. Aefsky, J.A. Aguilar-Saavedra, M. Agustoni, M. Aharrouche, S.P. Ahlen, F. Ahle, A. Ahmad, M. Ahsan, G. Aielli, T.P.A. Åkesson, G. Akimoto, A.V. Akimov, M.A. Alam, J. Albert, S. Albrand, M. Aleksa, I.N. Aleksandrov, F. Alessandria, C. Alexa, G. Alexander, G. Alexandre, T. Alexopoulo, M. Alhroob, M. Aliev, G. Alimonti, J. Alison, B.M.M. Allbrooke, P.P. Allport, S.E. Allwood-Spier, J. Almond, A. Aloisio, R. Alon, A. Alonso, F. Alonso, A. Altheimer, B. Alvarez Gonzalez, M.G. Alviggi, K. Amako, C. Amelung, V.V. Ammosov, S.P. Amor Dos Santo, A. Amorim, N. Amram, C. Anastopoulo, L.S. Ancu, N. Andari, T. Andeen, C.F. Ander, G. Ander, K.J. Anderson, A. Andreazza, V. Andrei, M-L. Andrieux, X.S. Anduaga, S. Angelidaki, P. Anger, A. Angerami, F. Anghinolfi, A. Anisenkov, N. Anjo, A. Annovi, A. Antonaki, M. Antonelli, A. Antonov, J. Anto, F. Anulli, M. Aoki, S. Aoun, L. Aperio Bella, R. Apolle, G. Arabidze, I. Aracena, Y. Arai, A.T.H. Arce, S. Arfaoui, J-F. Arguin, S. Argyropoulo, E. Arik, M. Arik, A.J. Armbruster, O. Arnaez, V. Arnal, A. Artamonov, G. Artoni, D. Arutinov, S. Asai, S. Ask, B. Åsman, L. Asquith, K. Assamagan, A. Astbury, M. Atkinson, B. Aubert, E. Auge, K. Augsten, M. Aurousseau, G. Avolio, D. Axen, G. Azuelo, Y. Azuma, M.A. Baak, G. Baccaglioni, C. Bacci, A.M. Bach, H. Bachacou, K. Bacha, M. Backe, M. Backhau, J. Backus Maye, E. Badescu, P. Bagnaia, S. Bahinipati, Y. Bai, D.C. Bailey, T. Bain, J.T. Baine, O.K. Baker, M.D. Baker, S. Baker, P. Balek, E. Bana, P. Banerjee, Sw. Banerjee, D. Banfi, A. Bangert, V. Bansal, H.S. Bansil, L. Barak, S.P. Baranov, A. Barbaro Galtieri, T. Barber, E.L. Barberio, D. Barberi, M. Barbero, D.Y. Bardin, T. Barillari, M. Barisonzi, T. Barklow, N. Barlow, B.M. Barnett, R.M. 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Bethke, W. Bhimji, R.M. Bianchi, L. Bianchini, M. Bianco, O. Biebel, S.P. Bieniek, K. Bierwagen, J. Biesiada, M. Biglietti, H. Bilokon, M. Bindi, S. Binet, A. Bingul, C. Bini, C. Biscarat, B. Bittner, C.W. Black, K.M. Black, R.E. Blair, J.-B. Blanchard, T. Blazek, I. Bloch, C. Blocker, J. Blocki, A. Blondel, W. Blum, U. Blumenschein, G.J. Bobbink, V.S. Bobrovnikov, S.S. Bocchetta, A. Bocci, C.R. Boddy, M. Boehler, J. Boek, T.T. Boek, N. Boelaert, J.A. Bogaert, A. Bogdanchikov, A. Bogouch, C. Bohm, J. Bohm, V. Boisvert, T. Bold, V. Boldea, N.M. Bolnet, M. Bomben, M. Bona, M. Boonekamp, S. Bordoni, C. Borer, A. Borisov, G. Borissov, I. Borjanovic, M. Borri, S. Borroni, J. Bortfeldt, V. Bortolotto, K. Bo, D. Boscherini, M. Bosman, H. Boterenbrood, J. Bouchami, J. Boudreau, E.V. Bouhova-Thacker, D. Boumediene, C. Bourdario, N. Bousson, A. Boveia, J. Boyd, I.R. Boyko, I. Bozovic-Jelisavcic, J. Bracinik, P. Branchini, A. Brandt, G. Brandt, O. Brandt, U. Bratzler, B. Brau, J.E. Brau, H.M. 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Iengo, Paolo, Izzo, Vincenzo, Sekhniaidze, Givi, Al, e. t. ., Universidade do Minho, G., Aad, Bianco, Michele, G., Chiodini, Gorini, Edoardo, Primavera, Margherita, Spagnolo, Stefania Antonia, Ventura, Andrea, ATLAS (IHEF, IoP, FNWI), Abdelalim Aly, Ahmed Aly, Alexandre, Gauthier, Backes, Moritz, Barone, Gaetano, Bell, Paul, Bell, William, Benhar Noccioli, Eleonora, Blondel, Alain, Bucci, Francesca, Clark, Allan Geoffrey, Dao, Valerio, Doglioni, Caterina, Ferrere, Didier, Gadomski, Szymon, Gonzalez Sevilla, Sergio, Goulette, Marc, Iacobucci, Giuseppe, La Rosa, Alessandro, Lister, Alison, Martin Dit Latour, Bertrand, Mermod, Philippe, Mora Herrera, Maria Clemencia Rosario, Nektarijevic, Snezana, Nikolics, Katalin, Pasztor, Arpad, Picazio, Attilio, Pohl, Martin, Rosbach, Kilian, Rosselet, Laurent, Wu, Xin, Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, and Çetin, Serkant Ali
Subjects: gauge mediation, Nuclear Theory, 7. Clean energy, 01 natural sciences, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), Naturvetenskap, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Nuclear Experiment, QC, Physics, Large Hadron Collider, Settore FIS/01 - Fisica Sperimentale, Supersymmetry, ATLAS, Supersymmetry breaking, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, Higgs boson, Gravitino, Física nuclear, LHC, Natural Sciences, Particle Physics - Experiment, Quark, supersymmetry, higgs boson, Particle physics, Nuclear and High Energy Physics, Ciências Naturais::Ciências Físicas, 530 Physics, Ciências Físicas [Ciências Naturais], FOS: Physical sciences, ddc:500.2, Bottom quark, Nuclear physics, 0103 physical sciences, ddc:530, High Energy Physics, 010306 general physics, Science & Technology, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Gauge mediation, Atlas detector, HADRON-HADRON COLLISIONS, Experimental High Energy Physics, Neutralino, Physics::Accelerator Physics, High Energy Physics::Experiment
Abstract: A search has been performed for the experimental signature of an isolated photon with high transverse momentum, at least one jet identified as originating from a bottom quark, and high missing transverse momentum. Such a final state may originate from supersymmetric models with gauge-mediated supersymmetry breaking in events in which one of a pair of higgsino-like neutralinos decays into a photon and a gravitino while the other decays into a Higgs boson and a gravitino. The search is performed using the full dataset of 7 TeV proton–proton collisions recorded with the ATLAS detector at the LHC in 2011, corresponding to an integrated luminosity of 4.7 fb−1. A total of 7 candidate events are observed while 7.5±2.2 events are expected from the Standard Model background. The results of the search are interpreted in the context of general gauge mediation to exclude certain regions of a benchmark plane for higgsino-like neutralino production., We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; EPLANET, ERC and NSRF, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNSF, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT and NSRF, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; BRF and RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America.
Published: 2013

5. Measurement of W gamma and Z gamma production cross sections in pp collisions at root s=7 TeV and limits on anomalous triple gauge couplings with the ATLAS detector

Author: Aad, G, Abbott, B, Abdallah, J, Khalek, SA, Abdelalim, AA, Abdinov, O, Abi, B, Abolins, M, AbouZeid, OS, Abramowicz, H, Abreu, H, Acerbi, E, Acharya, BS, Adamczyk, L, Adams, DL, Addy, TN, Adelman, J, Adomeit, S, Adragna, P, Adye, T, Aefsky, S, Aguilar-Saavedra, JA, Aharrouche, M, Ahlen, SP, Ahles, F, Ahmad, A, Ahsan, M, Aielli, G, Akdogan, T, Akesson, TPA, Akimoto, G, Akimov, AV, Akiyama, A, Alam, MS, Alam, MA, Albert, J, Albrand, S, Aleksa, M, Aleksandrov, IN, Alessandria, F, Alexa, C, Alexander, G, Alexandre, G, Alexopoulos, T, Alhroob, M, Aliev, M, Alimonti, G, Alison, J, Allbrooke, BMM, Allport, PP, Allwood-Spiers, SE, Almond, J, Aloisio, A, Alon, R, Alonso, A, Gonzalez, BA, Alviggi, MG, Amako, K, Amelung, C, Ammosov, VV, Amorim, A, Amram, N, Anastopoulos, C, Ancu, LS, Andari, N, Andeen, T, Anders, CF, Anders, G, Anderson, KJ, Andreazza, A, Andrei, V, Anduaga, XS, Angerami, A, Anghinolfi, F, Anisenkov, A, Anjos, N, Annovi, A, Antonaki, A, Antonelli, M, Antonov, A, Antos, J, Anulli, F, Aoun, S, Bella, LA, Apolle, R, Arabidze, G, Aracena, I, Arai, Y, Arce, ATH, Arfaoui, S, Arguin, JF, Arik, E, Arik, M, Armbruster, AJ, Arnaez, O, Arnal, V, Arnault, C, Artamonov, A, Artoni, G, Arutinov, D, Asai, S, Asfandiyarov, R, Ask, S, Asman, B, Asquith, L, Assamagan, K, Astbury, A, Aubert, B, Auge, E, Augsten, K, Aurousseau, M, Avolio, G, Avramidou, R, Axen, D, Azuelos, G, Azuma, Y, Baak, MA, Baccaglioni, G, Bacci, C, Bach, AM, Bachacou, H, Bachas, K, Backes, M, Backhaus, M, Badescu, E, Bagnaia, P, Bahinipati, S, Bai, Y, Bailey, DC, Bain, T, Baines, JT, Baker, OK, Baker, MD, Baker, S, Banas, E, Banerjee, P, Banerjee, S, Banfi, D, Bangert, A, Bansal, V, Bansil, HS, Barak, L, Baranov, SP, Galtieri, AB, Barber, T, Barberio, EL, Barberis, D, Barbero, M, Bardin, DY, Barillari, T, Barisonzi, M, Barklow, T, Barlow, N, Barnett, BM, Barnett, RM, Baroncelli, A, Barone, G, Barr, AJ, Barreiro, F, Da Costa, JBG, Barrillon, P, Bartoldus, R, Barton, AE, Bartsch, V, Bates, RL, Batkova, 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H, Salamanna, Giuseppe, Salamon, A, Saleem, M, Salek, D, Salihagic, D, Salnikov, A, Salt, J, Ferrando, Bm, Salvatore, D, Salvatore, F, Salvucci, A, Salzburger, A, Sampsonidis, D, Samset, Bh, Sanchez, A, Martinez, V, Sandaker, H, Sander, Hg, Sanders, Mp, Sandhoff, M, Sandoval, T, Sandoval, C, Sandstroem, R, Sankey, Dpc, Sansoni, A, Rios, C, Santoni, C, Santonico, R, Santos, H, Saraiva, Jg, Sarangi, T, Sarkisyan Grinbaum, E, Sarri, F, Sartisohn, G, Sasaki, O, Sasao, N, Satsounkevitch, I, Sauvage, G, Sauvan, E, Sauvan, Jb, Savard, P, Savinov, V, Savu, Do, Sawyer, L, Saxon, Dh, Saxon, J, Sbarra, C, Sbrizzi, A, Scallon, O, Scannicchio, Da, Scarcella, M, Schaarschmidt, J, Schacht, P, Schaefer, D, Schaefer, U, Schaepe, S, Schaetzel, S, Schaffer, Ac, Schaile, D, Schamberger, Rd, Schamov, Ag, Scharf, V, Schegelsky, Va, Scheirich, D, Schernau, M, Scherzer, Mi, Schiavi, C, Schieck, J, Schioppa, M, Schlenker, S, Schmidt, E, Schmieden, K, Schmitt, C, Schmitt, S, Schmitz, M, Schoning, A, Schott, M, Schouten, D, Schovancova, J, Schram, M, Schroeder, C, Schroer, N, Schultens, Mj, Schultes, J, Schultz Coulon, Hc, Schulz, H, Schumacher, Jw, Schumacher, M, Schumm, Ba, Schune, P, Schwanenberger, C, Schwartzman, A, Schwemling, P, Schwienhorst, R, Schwierz, R, Schwindling, J, Schwindt, T, Schwoerer, M, Sciolla, G, Scott, Wg, Searcy, J, Sedov, G, Sedykh, E, Seidel, Sc, Seiden, A, Seifert, F, Seixas, Jm, Sekhniaidze, G, Sekula, Sj, Selbach, Ke, Seliverstov, Dm, Sellden, B, Sellers, G, Seman, M, Semprini Cesari, N, Serfon, C, Serin, L, Serkin, L, Seuster, R, Severini, H, Sfyrla, A, Shabalina, E, Shamim, M, Shan, Ly, Shank, Jt, Shao, Qt, Shapiro, M, Shatalov, Pb, Shaw, K, Sherman, D, Sherwood, P, Shibata, A, Shichi, H, Shimizu, S, Shimojima, M, Shin, T, Shiyakova, M, Shmeleva, A, Shochet, Mj, Short, D, Shrestha, S, Shulga, E, Shupe, Ma, Sicho, P, Sidoti, A, Siegert, F, Sijacki, D, Silbert, O, Silva, J, Silver, Y, Silverstein, D, Silverstein, Sb, Simak, V, Simard, O, Simic, L, Simion, S, Simmons, B, Simoniello, R, Simonyan, M, Sinervo, P, Sinev, Nb, Sipica, V, Siragusa, G, Sircar, A, Sisakyan, An, Sivoklokov, Sy, Siolin, J, Sjursen, Tb, Skinnari, La, Skottowe, Hp, Skovpen, K, Skubic, P, Slater, M, Slavicek, T, Sliwa, K, Smakhtin, V, Smart, Bh, Smirnov, Sy, Smirnov, Y, Smirnova, Ln, Smirnova, O, Smith, Bc, Smith, D, Smith, Km, Smizanska, M, Smolek, K, Snesarev, Aa, Snow, Sw, Snow, J, Snyder, S, Soares, M, Sobie, R, Sodomka, J, Soffer, A, Solans, Ca, Solar, M, Solc, J, Soldatov, Ey, Soldevila, U, Camillocci, E, Solodkov, Aa, Solovyanov, Ov, Song, Hy, Soni, N, Sopko, V, Sopko, B, Sosebee, M, Soualah, R, Soukharev, A, Spagnolo, S, Spano, F, Spighi, R, Spigo, G, Spila, F, Spiwoks, R, Spousta, M, Spreitzer, T, Spurlock, B, St Denis, Rd, Stahlman, J, Stamen, R, Stanecka, E, Stanek, Rw, Stanescu, C, Stanescu Bellu, M, Stapnes, S, Starchenko, Ea, Stark, J, Staroba, P, Starovoitov, P, Staude, A, Stavina, P, Steele, G, Steinbach, P, Steinberg, P, Stekl, I, Stelzer, B, Stelzer, Hj, Stelzer Chilton, O, Stenzel, H, Stern, S, Stewart, Ga, Stillings, Ja, Stockton, Mc, Stoerig, K, Stoicea, G, Stonjek, S, Strachota, P, Stradling, Ar, Straessner, A, Strandberg, J, Strandberg, S, Strandlie, A, Strang, M, Strauss, E, Strauss, M, Strizenec, P, Stroehmer, R, Strom, Dm, Strong, Ja, Stroynowski, R, Strube, J, Stugu, B, Stumer, I, Stupak, J, Sturm, P, Styles, Na, Soh, Da, Su, D, Subramania, H, Succurro, A, Sugaya, Y, Suhr, C, Suita, K, Suk, M, Sulin, Vv, Sultansoy, S, Sumida, T, Sun, X, Sundermann, Je, Suruliz, K, Susinno, G, Sutton, Mr, Suzuki, Y, Svatos, M, Swedish, S, Sykora, I, Sykora, T, Sanchez, J, Ta, D, Tackmann, K, Taffard, A, Tafirout, R, Taiblum, N, Takahashi, Y, Takai, H, Takashima, R, Takeda, H, Takeshita, T, Takubo, Y, Talby, M, Talyshev, A, Tamsett, Mc, Tanaka, J, Tanaka, R, Tanaka, S, Tanasijczuk, Aj, Tani, K, Tannoury, N, Tapprogge, S, Tardif, D, Tarem, S, Tarrade, F, Tartarelli, Gf, Tas, P, Tasevsky, M, Tassi, E, Tatarkhanov, M, Tayalati, Y, Taylor, C, Taylor, Fe, Taylor, Gn, Taylor, W, Teinturier, M, Castanheira, Mtd, Teixeira Dias, P, Temming, Kk, Ten Kate, H, Teng, Pk, Terada, S, Terashi, K, Terron, J, Testa, M, Teuscher, Rj, Therhaag, J, Theveneaux Pelzer, T, Thioye, M, Thoma, S, Thomas, Jp, Thompson, En, Thompson, Pd, Thompson, A, Thomsen, La, Thomson, E, Thomson, M, Thun, Rp, Tian, F, Tibbetts, Mj, Tic, T, Tikhomirov, Vo, Tikhonov, Ya, Timoshenko, S, Tipton, P, Viegas, Fjta, Tisserant, S, Todorov, T, Todorova Nova, S, Toggerson, B, Tojo, J, Tokar, S, Tokunaga, K, Tokushuku, K, Tollefson, K, Tomoto, M, Tompkins, L, Toms, K, Tonoyan, A, Topfel, C, Topilin, Nd, Torchiani, I, Torrence, E, Torres, H, Pastor, Et, Toth, J, Touchard, F, Tovey, Dr, Trefzger, T, Tremblet, L, Tricoli, A, Trigger, Im, Trincaz Duvoid, S, Trinh, Tn, Tripiana, Mf, Trischuk, W, Trocme, B, Troncon, C, Trottier McDonald, M, Trzebinski, M, Trzupek, A, Tsarouchas, C, Tseng, Jcl, Tsiakiris, M, Tsiareshka, Pv, Tsionou, D, Tsipolitis, G, Tsiskaridze, V, Tskhadadze, Eg, Tsukerman, Ii, Tsulaia, V, Tsung, Jw, Tsuno, S, Tsybychev, D, Tua, A, Tudorache, A, Tudorache, V, Tuggle, Jm, Turala, M, Turecek, D, Cakir, It, Turlay, E, Turra, R, Tuts, Pm, Tykhonov, A, Tylmad, M, Tyndel, M, Tzanakos, G, Uchida, K, Ueda, I, Ueno, R, Ugland, M, Uhlenbrock, M, Uhrmacher, M, Ukegawa, F, Unal, G, Undrus, A, Unel, G, Unno, Y, Urbaniec, D, Usai, G, Uslenghi, M, Vacavant, L, Vacek, V, Vachon, B, Vahsen, S, Valenta, J, Valente, P, Valentinetti, S, Valkar, S, Gallego, Ev, Vallecorsa, S, Ferrer, Jav, Van der Graaf, H, Van der Kraaij, E, Van der Leeuw, R, Van der Poel, E, Van der Ster, D, Van Eldik, N, Van Gemmeren, P, Van Vulpen, I, Vanadia, M, Vandelli, W, Vaniachine, A, Vankov, P, Vannucci, F, Vari, R, Varnes, Ew, Varol, T, Varouchas, D, Vartapetian, A, Varvell, Ke, Vassilakopoulos, Vi, Vazeille, F, Schroeder, Tv, Vegni, G, Veillet, Jj, Veloso, F, Veness, R, Veneziano, S, Ventura, A, Ventura, D, Venturi, M, Venturi, N, Vercesil, V, Verducci, M, Verkerke, W, Vermeulen, Jc, Vest, A, Vetterli, Mc, Vichou, I, Vickey, T, Boeriu, Oev, Viehhauser, Gha, Viel, S, Villa, M, Perez, Mv, Vilucchi, E, Vincter, Mg, Vinek, E, Vinogradov, Vb, Virchaux, M, Virzi, J, Vitells, O, Viti, M, Vivarelli, I, Vaque, Fv, Vlachos, S, Vladoiu, D, Vlasak, M, Vogel, A, Vokac, P, Volpi, G, Volpi, M, Volpini, G, Von der Schmitt, H, Von Loeben, J, Von Radziewski, H, Von Toerne, E, Vorobel, V, Vorwerk, V, Vos, M, Voss, R, Voss, Tt, Vossebeld, Jh, Vranjes, N, Milosavljevic, Mv, Vrba, V, Vreeswijk, M, Anh, Tv, Vuillermet, R, Vukotic, I, Wagner, W, Wagner, P, Wahlen, H, Wahrmund, S, Wakabayashi, J, Walch, S, Walder, J, Walker, R, Walkowiak, W, Wall, R, Waller, P, Wang, C, Wang, H, Wang, J, Wang, R, Wang, Sm, Wang, T, Warburton, A, Ward, Cp, Warsinsky, M, Washbrook, A, Wasicki, C, Watkins, Pm, Watson, At, Watson, Ij, Watson, Mf, Watts, G, Watts, S, Waugh, At, Waugh, Bm, Weber, M, Weber, P, Weidberg, Ar, Weigell, P, Weingarten, J, Weiser, C, Wellenstein, H, Wells, P, Wenaus, T, Wendland, D, Weng, Z, Wengler, T, Wenig, S, Wermes, N, Werner, M, Werner, P, Werth, M, Wessels, M, Wetter, J, Weydert, C, Whalen, K, Wheeler Ellis, Sj, White, A, White, Mj, White, S, Whitehead, Sr, Whiteson, D, Whittington, D, Wicek, F, Wicke, D, Wickens, Fj, Wiedenmann, W, Wielers, M, Wienemann, P, Wiglesworth, C, Wiik Fuchs, Lam, Wijeratne, Pa, Wildauer, A, Wildt, Ma, Wilhelm, I, Wilkens, Hg, Will, Jz, Williams, E, Williams, Hh, Willis, W, Willocq, S, Wilson, Ja, Wilson, Mg, Wilson, A, Wingerter Seez, I, Winkelmann, S, Winklmeier, F, Wittgen, M, Wolter, Mw, Wolters, H, Wong, Wc, Wooden, G, Wosiek, Bk, Wotschack, J, Woudstra, Mj, Wozniak, Kw, Wraight, K, Wright, C, Wright, M, Wrona, B, Wu, Sl, Wu, X, Wu, Y, Wulf, E, Wynne, Bm, Xella, S, Xiao, M, Xie, S, Xu, C, Xu, D, Yabsley, B, Yacoob, S, Yamada, M, Yamaguchi, H, Yamamoto, A, Yamamoto, K, Yamamoto, S, Yamamura, T, Yamanaka, T, Yamaoka, J, Yamazaki, T, Yamazaki, Y, Yan, Z, Yang, H, Yang, Uk, Yang, Y, Yang, Z, Yanush, S, Yao, L, Yao, Y, Yasu, Y, Smit, Gvy, Ye, J, Ye, S, Yilmaz, M, Yoosoofmiya, R, Yorita, K, Yoshida, R, Young, C, Young, Cj, Youssef, S, Yu, D, Yu, J, Yuan, L, Yurkewicz, A, Zabinski, B, Zaidan, R, Zaitsev, Am, Zajacova, Z, Zanello, L, Zaytsev, A, Zeitnitz, C, Zeman, M, Zemla, A, Zendler, C, Zenin, O, Zenis, T, Zinonos, Z, Zenz, S, Zerwas, D, Della Porta, Gz, Zhan, Z, Zhang, D, Zhang, H, Zhang, J, Zhang, X, Zhang, Z, Zhao, L, Zhao, T, Zhao, Z, Zhemchugov, A, Zhong, J, Zhou, B, Zhou, N, Zhou, Y, Zhu, Cg, Zhu, H, Zhu, J, Zhu, Y, Zhuang, X, Zhuravlov, V, Zieminska, D, Zimmermann, R, Zimmermann, S, Ziolkowski, M, Zitoun, R, Zivkovic, L, Zmouchko, Vv, Zobernig, G, Zoccoli, A, Zsenei, A, Zur Nedden, M, Zutshi, V, and Zwalinski, L.
Subjects: Settore FIS/01 - Fisica Sperimentale
Published: 2012

6. Prognostic significance of SSEP, BAEP and serum S-100B monitoring after aneurysm surgery

Author: Hans-Ekkehart Vitzthum, Meyer Jj, Uta Schick, and Döhnert J
Subjects: Subarachnoid hemorrhage, business.industry, Ischemia, Infarction, General Medicine, Brain damage, medicine.disease, Central nervous system disease, Aneurysm, Neurology, Somatosensory evoked potential, Anesthesia, Predictive value of tests, medicine, Neurology (clinical), medicine.symptom, business
Abstract: Objective – Changes in evoked potentials (EPs) and increased levels of S-100B protein were used to identify cerebral ischemia or glial damage and to predict neurological outcome in aneurysm patients. Material and methods – Somatosensory evoked potentials and Brainstem auditory-evoked potentials, and serum S-100B protein were simultaneously investigated pre- and postoperatively over a period of 10 days in 43 patients with 47 aneurysms (six in the posterior fossa). Results – The EP scores showed a strong correlation with the clinical outcome. Sensitivity was 73%, and specificity 81%. Pathological S-100B levels >0.5 mg/l were equal in predictive values (correct positive eight, false positive six, correct negative 26, false negative three). Initially increased S-100B levels, long-lasting S-100B elevation, and secondary increasing S-100B values correlated with an unfavorable outcome. High peak S-100B values correlated with bad EP scores at discharge. EP deterioration was the first indicator anticipating S-100B elevation and clinical deterioration in five patients. There was a good correlation between pathological S-100B values or EP findings and infarction on CT scan. Conclusions – Both EPs and S-100B protein showed a comparable high predictive value for outcome. S-100B reflects the extent of primary brain damage after subarachnoid hemorrhage and time course of ongoing secondary brain damage. Evoked potentials assess the functional integrity and tended to react earlier than S-100B protein before definitive structural damage occurred.
Published: 2003

7. Models for the longitudinal genetic analysis of same-age twins: application to HDL cholesterol

Author: Richard M. Schieken, John K. Hewitt, Michael C. Neale, Lindon J. Eaves, Meyer Jj, Joann Bodurtha, Walter E. Nance, J Segrest, and Hermine H. Maes
Subjects: Male, Genetics, Multivariate statistics, Adolescent, Models, Genetic, Longitudinal data, Cholesterol, Early adolescence, Cholesterol, HDL, Age Factors, Twins, Obstetrics and Gynecology, Biology, Covariance, Heritability, Genetic analysis, chemistry.chemical_compound, chemistry, Pediatrics, Perinatology and Child Health, Humans, Female, Longitudinal Studies, Child, Genetics (clinical)
Abstract: Models are presented for the analysis of longitudinal data from same-age twins which permit the exploration of a remarkably diverse array of alternative explanations for continuity and change during development. Data of this type permit the detection of new sources of genetic or environmental covariation during development that are not expressed at earlier ages and, because they include the effects of age-specific genes, the resulting heritability estimates are more reliable than those obtained from relatives who differ in age. The proposed models were applied to measurements of HDL cholesterol obtained on 81 pairs of monozygotic (MZ) twins and 69 dizygotic (DZ) pairs at 11, 12.5 and 14 years of age. All three MZ co-twin correlations were substantially higher than the self correlations across occasions, suggesting that new sources of genetic or environmental covariation must be expressed during early adolescence. This interpretation was confirmed by analysis of the full covariance matrices which showed that only models which assumed the expression of new or age-specific genes could explain the observed pattern of covariation. Because they include the effects of age-specific genes, the resulting heritabilities (0.80–0.83) were substantially higher than many previous estimates.
Published: 1998

8. Experimental Nephrotoxicity of the Radiocontrast Agents Iohexol, Ioxaglate, and Iothalamate

Author: Mayer Brezis, Herman M, Meyer Jj, Samuel N. Heyman, Seymour Rosen, and Greenfeld Z
Subjects: Male, Iohexol, Indomethacin, Ioxaglic acid, Renal function, In Vitro Techniques, Pharmacology, Kidney, Renal Circulation, Nephrotoxicity, Furosemide, In vivo, Ioxaglic Acid, Animals, Medicine, Radiology, Nuclear Medicine and imaging, Renal circulation, business.industry, Angiotensin II, Sodium, General Medicine, Diet, Sodium-Restricted, Iothalamic Acid, Rats, Kidney Tubules, medicine.anatomical_structure, business, Glomerular Filtration Rate, medicine.drug
Abstract: The authors compared the renal toxicity of the low osmolality radiocontrast agents, iohexol and ioxaglate, and the ionic agent, iothalamate, at equivalent iodine dose, using experimental models in vitro and in vivo. In isolated perfused rat kidneys, all agents induced comparable biphasic hemodynamic changes, associated with similar declines in glomerular filtration rate (GFR) and tubular necrosis. In two different in vivo models (using multiple insults combined with the administration of radiocontrast), iothalamate appeared to induce more severe morphologic injury. Despite similar nephrotoxic potential in vitro, the newer radiocontrast agents, iohexol and ioxaglate, cause in vivo less renal injury than iothalamate in the experimental models.
Published: 1991

9. Foundations of Multi-Agent systems: techniques, tools and theory

Author: Lee, LC, Collis, JC, Binmore, K, Vulcan, N, van Eijk, RM, de Boer, FS, van der Hoek, W, Meyer, JJ Ch, Padget, J, Bradford, R, d'Inverno, Mark, Luck, Michael, and Fisher, Michael
Published: 1998

10. What's new in laser treatment for glaucoma?

Author: Meyer JJ and Lawrence SD
Published: 2012
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11. Intensity-modulated radiation therapy for anal cancer.

Author: Czito BG, Pepek JM, Meyer JJ, Yoo S, and Willett CG
Abstract: The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these positive results is the high rate of treatment-related morbidity associated with chemoradiation therapy for anal cancer. The use of intensity-modulated radiation therapy (IMRT) has the potential to reduce acute and chronic treatment-related toxicity, minimize treatment breaks, and potentially improve disease-related outcomes by permitting radiation dose escalation in selected cases. [ABSTRACT FROM AUTHOR]
Published: 2009

12. Phakic intraocular lenses.

Author: Espandar L, Meyer JJ, and Moshirfar M
Published: 2008
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13. Effects of small doses of bromazepam on pupillary function and on flicker perception in normal subjects

Author: Avinoam B. Safran, Pierre Schulz, Assimacopoulos A, André Roth, Meyer Jj, and A Walser
Subjects: Adult, Bromazepam, medicine.medical_specialty, business.industry, media_common.quotation_subject, Flicker, Pupil, Function (mathematics), Audiology, Flicker Fusion, Psychiatry and Mental health, Anti-Anxiety Agents, Perception, medicine, Humans, Pharmacology (medical), business, media_common, medicine.drug
Published: 1987

14. Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions.

Author: Wu QJ, Wang Z, Kirkpatrick JP, Chang Z, Meyer JJ, Lu M, Huntzinger C, Yin FF, Wu, Q Jackie, Wang, Zhiheng, Kirkpatrick, John P, Chang, Zheng, Meyer, Jeffrey J, Lu, Mei, Huntzinger, Calvin, and Yin, Fang-Fang
Abstract: Background: This study evaluated the dosimetric impact of various treatment techniques as well as collimator leaf width (2.5 vs 5 mm) for three groups of tumors -- spine tumors, brain tumors abutting the brainstem, and liver tumors. These lesions often present challenges in maximizing dose to target volumes without exceeding critical organ tolerance. Specifically, this study evaluated the dosimetric benefits of various techniques and collimator leaf sizes as a function of lesion size and shape.Methods: Fifteen cases (5 for each site) were studied retrospectively. All lesions either abutted or were an integral part of critical structures (brainstem, liver or spinal cord). For brain and liver lesions, treatment plans using a 3D-conformal static technique (3D), dynamic conformal arcs (DARC) or intensity modulation (IMRT) were designed with a conventional linear accelerator with standard 5 mm leaf width multi-leaf collimator, and a linear accelerator dedicated for radiosurgery and hypofractionated therapy with a 2.5 mm leaf width collimator. For the concave spine lesions, intensity modulation was required to provide adequate conformality; hence, only IMRT plans were evaluated using either the standard or small leaf-width collimators.A total of 70 treatment plans were generated and each plan was individually optimized according to the technique employed. The Generalized Estimating Equation (GEE) was used to separate the impact of treatment technique from the MLC system on plan outcome, and t-tests were performed to evaluate statistical differences in target coverage and organ sparing between plans.Results: The lesions ranged in size from 2.6 to 12.5 cc, 17.5 to 153 cc, and 20.9 to 87.7 cc for the brain, liver, and spine groups, respectively. As a group, brain lesions were smaller than spine and liver lesions. While brain and liver lesions were primarily ellipsoidal, spine lesions were more complex in shape, as they were all concave. Therefore, the brain and the liver groups were compared for volume effect, and the liver and spine groups were compared for shape. For the brain and liver groups, both the radiosurgery MLC and the IMRT technique contributed to the dose sparing of organs-at-risk(OARs), as dose in the high-dose regions of these OARs was reduced up to 15%, compared to the non-IMRT techniques employing a 5 mm leaf-width collimator. Also, the dose reduction contributed by the fine leaf-width MLC decreased, as dose savings at all levels diminished from 4 - 11% for the brain group to 1 - 5% for the liver group, as the target structures decreased in volume. The fine leaf-width collimator significantly improved spinal cord sparing, with dose reductions of 14 - 19% in high to middle dose regions, compared to the 5 mm leaf width collimator.Conclusion: The fine leaf-width MLC in combination with the IMRT technique can yield dosimetric benefits in radiosurgery and hypofractionated radiotherapy. Treatment of small lesions in cases involving complex target/OAR geometry will especially benefit from use of a fine leaf-width MLC and the use of IMRT. [ABSTRACT FROM AUTHOR]
Published: 2009
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15. Antitumor, antioxidant and antimicrobial activities of Bersama engleriana (Melianthaceae)

Author: Kuete V, Mbaveng AT, Tsaffack M, Beng VP, Etoa FX, Nkengfack AE, Meyer JJ, and Lall N
Abstract: The aim of this study was to evaluate the antitumor, antioxidant and antimicrobial activities as well as the phytochemical composition and the acute toxicity of the methanolic extracts from the roots (BER), stem bark (BEB), leaves (BEL) and wood (BEW) of Bersama engleriana. The crown gall tumor and DPPH radical scavenging assays were used to detect respectively the antitumoral and oxidant activities. Agar diffusion and liquid dilution were used for antimicrobial tests and the phytochemical assays were conducted according to Harbone methods. The single-dose oral toxicity test was performed in accordance with the OPPTS 870.1100 and OECD 401guidelines. The phytochemical tests indicated the presence of flavonoids, phenols, triterpenes and anthraquinones in all extracts. Pronounced tumor reducing activity was observed with the extracts from the roots (69.32%) and leaves (65.42%). The DPPH scavenging activity showed that the extract from the leaves was the most active with 93.71% inhibition rate at the 1000mug/ml. The results of antimicrobial activity showed that all tested extracts were active against all tested microbial species, including Gram-positive, and negative bacteria, the two Candida species and mycobacteria. The MIC values obtained ranged from 9.76 to 156.25mug/ml. Under the conditions of the studied toxicity, all extracts were found to be non-toxic. The overall results of this study indicates that the extracts from the roots, stem bark, leaves and wood have interesting antioxidant properties and represent a potential source of medicine for the treatment of infectious diseases and cancer. [ABSTRACT FROM AUTHOR]
Published: 2008
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16. Measurement of the top quark pair production cross-section with ATLAS in the single lepton channel

Author: G. AAD, E. ABAT, B. ABBOTT, J. ABDALLAH, A. A. ABDELALIM, A. ABDESSELAM, O. ABDINOV, B. ABI, M. ABOLINS, H. ABRAMOWICZ, H. ABREU, E. ACERBI, B. S. ACHARYA, M. ACKERS, D. L. ADAMS, T. N. ADDY, J. ADELMAN, M. ADERHOLZ, C. ADORISIO, P. ADRAGNA, T. ADYE, S. AEFSKY, J. A. AGUILAR SAAVEDRA, M. AHARROUCHE, S. P. AHLEN, F. AHLES, A. AHMAD, H. AHMED, M. AHSAN, G. AIELLI, T. AKDOGAN, P. F. AKESSON, T. P. A. AKESSON, G. AKIMOTO, A. V. AKIMOV, A. AKTAS, M. S. ALAM, M. A. ALAM, J. ALBERT, S. ALBRAND, M. ALEKSA, I. N. ALEKSANDROV, M. ALEPPO, F. ALESSANDRIA, C. ALEXA, G. ALEXANDER, G. ALEXANDRE, T. ALEXOPOULOS, M. ALHROOB, M. ALIEV, G. ALIMONTI, J. ALISON, M. ALIYEV, P. P. ALLPORT, S. E. ALLWOOD SPIERS, J. ALMOND, A. ALOISIO, R. ALON, A. ALONSO, J. ALONSO, M. G. ALVIGGI, K. AMAKO, P. AMARAL, G. AMBROSINI, G. AMBROSIO, C. AMELUNG, V. V. AMMOSOV, A. AMORIM, G. AMOROS, N. AMRAM, C. ANASTOPOULOS, T. ANDEEN, C. F. ANDERS, K. J. ANDERSON, A. ANDREAZZA, V. ANDREI, M. L. ANDRIEUX, X. S. ANDUAGA, A. ANGERAMI, F. ANGHINOLFI, N. ANJOS, A. ANNOVI, A. ANTONAKI, M. ANTONELLI, S. ANTONELLI, J. ANTOS, B. ANTUNOVIC, F. ANULLI, S. AOUN, G. ARABIDZE, I. ARACENA, Y. ARAI, A. T. H. ARCE, J. P. ARCHAMBAULT, S. ARFAOUI, J. F. ARGUIN, T. ARGYROPOULOS, E. ARIK, M. ARIK, A. J. ARMBRUSTER, K. E. ARMS, S. R. ARMSTRONG, O. ARNAEZ, C. ARNAULT, A. ARTAMONOV, D. ARUTINOV, M. ASAI, S. ASAI, R. ASFANDIYAROV, S. ASK, B. ASMAN, D. ASNER, L. ASQUITH, K. ASSAMAGAN, A. ASTBURY, A. ASTVATSATOUROV, B. ATHAR, G. ATOIAN, B. AUBERT, B. AUERBACH, E. AUGE, K. AUGSTEN, M. AUROUSSEAU, N. AUSTIN, G. AVOLIO, R. AVRAMIDOU, D. AXEN, C. AY, G. AZUELOS, Y. AZUMA, M. A. BAAK, G. BACCAGLIONI, C. BACCI, A. M. BACH, H. BACHACOU, K. BACHAS, G. BACHY, M. BACKES, E. BADESCU, P. BAGNAIA, Y. BAI, D. C. BAILEY, T. BAIN, J. T. BAINES, O. K. BAKER, M. D. BAKER, S. BAKER, F. BALTASAR DOS SANTOS PEDROSA, E. BANAS, P. BANERJEE, S. BANERJEE, D. BANFI, A. BANGERT, V. BANSAL, S. P. BARANOV, S. BARANOV, A. BARASHKOU, T. BARBER, E. L. BARBERIO, D. BARBERIS, M. BARBERO, D. Y. BARDIN, T. BARILLARI, M. BARISONZI, T. BARKLOW, N. BARLOW, B. M. BARNETT, R. M. BARNETT, A. BARONCELLI, M. BARONE, A. J. BARR, F. BARREIRO, J. BARREIRO GUIMARAES DA COSTA, P. BARRILLON, V. BARTHELD, H. BARTKO, R. BARTOLDUS, D. BARTSCH, R. L. BATES, S. BATHE, L. BATKOVA, J. R. BATLEY, A. BATTAGLIA, M. BATTISTIN, G. BATTISTONI, F. BAUER, H. S. BAWA, M. BAZALOVA, B. BEARE, T. BEAU, P. H. BEAUCHEMIN, R. BECCHERLE, N. BECERICI, P. BECHTLE, G. A. BECK, H. P. BECK, M. BECKINGHAM, K. H. BECKS, A. J. BEDDALL, A. BEDDALL, V. A. BEDNYAKOV, C. BEE, M. BEGEL, S. BEHAR HARPAZ, P. K. BEHERA, M. BEIMFORDE, G. A. N. BELANGER, C. BELANGER CHAMPAGNE, B. BELHORMA, P. J. BELL, W. H. BELL, G. BELLA, L. BELLAGAMBA, F. BELLINA, G. BELLOMO, M. BELLOMO, A. BELLONI, K. BELOTSKIY, O. BELTRAMELLO, A. BELYMAM, S. BEN AMI, O. BENARY, D. BENCHEKROUN, C. BENCHOUK, M. BENDEL, B. H. BENEDICT, N. BENEKOS, Y. BENHAMMOU, G. P. BENINCASA, D. P. BENJAMIN, M. BENOIT, J. R. BENSINGER, K. BENSLAMA, S. BENTVELSEN, M. BERETTA, D. BERGE, E. BERGEAAS KUUTMANN, N. BERGER, F. BERGHAUS, E. BERGLUND, J. BERINGER, K. BERNARDET, P. BERNAT, R. BERNHARD, C. BERNIUS, T. BERRY, F. BERTINELLI, S. BERTOLUCCI, M. I. BESANA, N. BESSON, S. BETHKE, R. M. BIANCHI, M. BIANCO, O. BIEBEL, M. BIERI, J. BIESIADA, M. BIGLIETTI, H. BILOKON, M. BINDER, S. BINET, A. BINGUL, C. BINI, C. BISCARAT, R. BISCHOF, U. BITENC, K. M. BLACK, R. E. BLAIR, O. BLANCH, J. B. BLANCHARD, G. BLANCHOT, C. BLOCKER, J. BLOCKI, A. BLONDEL, W. BLUM, U. BLUMENSCHEIN, C. BOARETTO, G. J. BOBBINK, A. BOCCI, D. BOCIAN, R. BOCK, M. BOEHLER, M. BOEHM, J. BOEK, N. BOELAERT, S. BOSER, J. A. BOGAERTS, A. BOGOUCH, C. BOHM, J. BOHM, V. BOISVERT, T. BOLD, V. BOLDEA, A. BOLDYREV, V. G. BONDARENKO, M. BONDIOLI, R. BONINO, M. BOONEKAMP, G. BOORMAN, M. BOOSTEN, C. N. BOOTH, P. S. L. BOOTH, P. BOOTH, J. R. A. BOOTH, S. BORDONI, C. BORER, K. BORER, A. BORISOV, G. BORISSOV, I. BORJANOVIC, S. BORRONI, K. BOS, D. BOSCHERINI, M. BOSMAN, H. BOTERENBROOD, D. BOTTERILL, J. BOUCHAMI, J. BOUDREAU, E. V. BOUHOVA THACKER, C. BOULAHOUACHE, C. BOURDARIOS, A. BOVEIA, J. BOYD, B. H. BOYER, I. R. BOYKO, N. I. BOZHKO, I. BOZOVIC JELISAVCIC, S. BRACCINI, J. BRACINIK, A. BRAEM, E. BRAMBILLA, P. BRANCHINI, G. W. BRANDENBURG, A. BRANDT, G. BRANDT, O. BRANDT, U. BRATZLER, B. BRAU, J. E. BRAU, H. M. BRAUN, S. BRAVO, B. BRELIER, J. BREMER, R. BRENNER, S. BRESSLER, D. BRETON, N. D. BRETT, P. G. BRIGHT THOMAS, D. BRITTON, F. M. BROCHU, I. BROCK, R. BROCK, T. J. BRODBECK, E. BRODET, F. BROGGI, C. BROMBERG, G. BROOIJMANS, W. K. BROOKS, G. BROWN, E. BRUBAKER, P. A. BRUCKMAN DE RENSTROM, D. BRUNCKO, R. BRUNELIERE, S. BRUNET, A. BRUNI, G. BRUNI, M. BRUSCHI, T. BUANES, F. BUCCI, J. BUCHANAN, N. J. BUCHANAN, P. BUCHHOLZ, A. G. BUCKLEY, I. A. BUDAGOV, B. BUDICK, V. BUSCHER, L. BUGGE, D. BUIRA CLARK, E. J. BUIS, F. BUJOR, O. BULEKOV, M. BUNSE, T. BURAN, H. BURCKHART, S. BURDIN, T. BURGESS, S. BURKE, E. BUSATO, P. BUSSEY, C. P. BUSZELLO, F. BUTIN, B. BUTLER, J. M. BUTLER, C. M. BUTTAR, J. M. BUTTERWORTH, T. BYATT, J. CABALLERO, S. CABRERA URBAN, M. CACCIA, O. CAKIR, P. CALAFIURA, G. CALDERINI, P. CALFAYAN, R. CALKINS, L. P. CALOBA, R. CALOI, D. CALVET, A. CAMARD, P. CAMARRI, M. CAMBIAGHI, D. CAMERON, J. CAMMIN, S. CAMPANA, M. CAMPANELLI, V. CANALE, F. CANELLI, A. CANEPA, J. CANTERO, L. CAPASSO, M. D. M. CAPEANS GARRIDO, I. CAPRINI, M. CAPRINI, M. CAPRIO, M. CAPUA, R. CAPUTO, C. CARAMARCU, R. CARDARELLI, L. CARDIEL SAS, T. CARLI, G. CARLINO, L. CARMINATI, B. CARON, S. CARON, C. CARPENTIERI, G. D. CARRILLO MONTOYA, S. CARRON MONTERO, A. A. CARTER, J. R. CARTER, J. CARVALHO, D. CASADEI, M. P. CASADO, M. CASCELLA, C. CASO, A. M. CASTANEDA HERNADEZ, E. CASTANEDA MIRANDA, V. CASTILLO GIMENEZ, N. F. CASTRO, F. CASTROVILLARI, G. CATALDI, F. CATANEO, A. CATINACCIO, J. R. CATMORE, A. CATTAI, G. CATTANI, S. CAUGHRON, D. CAUZ, A. CAVALLARI, P. CAVALLERI, D. CAVALLI, M. CAVALLI SFORZA, V. CAVASINNI, A. CAZZATO, F. CERADINI, C. CERNA, A. S. CERQUEIRA, A. CERRI, L. CERRITO, F. CERUTTI, M. CERVETTO, S. A. CETIN, F. CEVENINI, A. CHAFAQ, D. CHAKRABORTY, K. CHAN, J. D. CHAPMAN, J. W. CHAPMAN, E. CHAREYRE, D. G. CHARLTON, S. CHARRON, S. CHATTERJII, V. CHAVDA, S. CHEATHAM, S. CHEKANOV, S. V. CHEKULAEV, G. A. CHELKOV, H. CHEN, L. CHEN, S. CHEN, T. CHEN, X. CHEN, S. CHENG, A. CHEPLAKOV, V. F. CHEPURNOV, R. CHERKAOUI EL MOURSLI, V. TCHERNIATINE, D. CHESNEANU, E. CHEU, S. L. CHEUNG, L. CHEVALIER, F. CHEVALLIER, V. CHIARELLA, G. CHIEFARI, L. CHIKOVANI, J. T. CHILDERS, A. CHILINGAROV, G. CHIODINI, V. CHIZHOV, G. CHOUDALAKIS, S. CHOURIDOU, T. CHRISTIANSEN, I. A. CHRISTIDI, A. CHRISTOV, D. CHROMEK BURCKHART, M. L. CHU, J. CHUDOBA, G. CIAPETTI, E. CICALINI, A. K. CIFTCI, R. CIFTCI, D. CINCA, V. CINDRO, M. D. CIOBOTARU, C. CIOCCA, A. CIOCIO, M. CIRILLI, M. CITTERIO, A. CLARK, P. J. CLARK, W. CLELAND, J. C. CLEMENS, B. CLEMENT, C. CLEMENT, D. CLEMENTS, R. W. CLIFFT, Y. COADOU, M. COBAL, A. COCCARO, J. COCHRAN, R. COCO, P. COE, S. COELLI, J. COGGESHALL, E. COGNERAS, C. D. COJOCARU, J. COLAS, B. COLE, A. P. COLIJN, C. COLLARD, N. J. COLLINS, C. COLLINS TOOTH, J. COLLOT, G. COLON, R. COLUCCIA, G. COMUNE, P. CONDE MUINO, E. CONIAVITIS, M. CONSONNI, S. CONSTANTINESCU, C. CONTA, F. CONVENTI, J. COOK, M. COOKE, B. D. COOPER, A. M. COOPER SARKAR, N. J. COOPER SMITH, K. COPIC, T. CORNELISSEN, M. CORRADI, S. CORREARD, F. CORRIVEAU, A. CORSO RADU, A. CORTES GONZALEZ, G. CORTIANA, G. COSTA, M. J. COSTA, D. COSTANZO, T. COSTIN, D. COTE, R. COURA TORRES, L. COURNEYEA, C. COUYOUMTZELIS, G. COWAN, C. COWDEN, B. E. COX, K. CRANMER, J. CRANSHAW, M. CRISTINZIANI, G. CROSETTI, R. CRUPI, S. CREPE RENAUDIN, C. CUENCA ALMENAR, T. CUHADAR DONSZELMANN, S. CUNEO, A. CUNHA, M. CURATOLO, C. J. CURTIS, P. CWETANSKI, Z. CZYCZULA, S. D'AURIA, M. D'ONOFRIO, A. D'ORAZIO, A. DA ROCHA GESUALDI MELLO, P. V. M. DA SILVA, C. DA VIA, W. DABROWSKI, A. DAHLHOFF, T. DAI, C. DALLAPICCOLA, S. J. DALLISON, J. DALMAU, C. H. DALY, M. DAM, M. DAMERI, H. O. DANIELSSON, R. DANKERS, D. DANNHEIM, V. DAO, G. DARBO, G. L. DARLEA, C. DAUM, J. P. DAUVERGNE, W. DAVEY, T. DAVIDEK, D. W. DAVIDSON, N. DAVIDSON, R. DAVIDSON, M. DAVIES, A. R. DAVISON, I. DAWSON, J. W. DAWSON, R. K. DAYA, K. DE, R. DE ASMUNDIS, P. E. DE CASTRO FARIA SALGADO, S. DE CECCO, J. DE GRAAT, N. DE GROOT, P. DE JONG, E. DE LA CRUZ BURELO, C. DE LA TAILLE, B. DE LOTTO, L. DE MORA, M. DE OLIVEIRA BRANCO, D. DE PEDIS, P. DE SAINTIGNON, A. DE SALVO, U. DE SANCTIS, A. DE SANTO, J. B. DE VIVIE DE REGIE, G. DE ZORZI, S. DEAN, H. DEBERG, G. DEDES, D. V. DEDOVICH, P. O. DEFAY, J. DEGENHARDT, M. DEHCHAR, M. DEILE, C. DEL PAPA, J. DEL PESO, T. DEL PRETE, A. DELL'ACQUA, L. DELL'ASTA, M. DELLA PIETRA, D. DELLA VOLPE, M. DELMASTRO, P. DELPIERRE, N. DELRUELLE, P. A. DELSART, C. DELUCA, S. DEMERS, M. DEMICHEV, B. DEMIRKOZ, J. DENG, W. DENG, S. P. DENISOV, C. DENNIS, J. E. DERKAOUI, F. DERUE, P. DERVAN, K. DESCH, P. O. DEVIVEIROS, A. DEWHURST, B. DEWILDE, S. DHALIWAL, R. DHULLIPUDI, A. DI CIACCIO, L. DI CIACCIO, A. DI DOMENICO, A. DI GIROLAMO, B. DI GIROLAMO, S. DI LUISE, A. DI MATTIA, R. DI NARDO, A. DI SIMONE, M. A. DIAZ, M. M. DIAZ GOMEZ, F. DIBLEN, E. B. DIEHL, H. DIETL, J. DIETRICH, T. A. DIETZSCH, S. DIGLIO, K. DINDAR YAGCI, D. J. DINGFELDER, C. DIONISI, R. DIPANJAN, P. DITA, S. DITA, F. DITTUS, F. DJAMA, R. DJILKIBAEV, T. DJOBAVA, M. A. B. DO VALE, A. DO VALLE WEMANS, T. K. O. DOAN, M. DOBBS, R. DOBINSON, D. DOBOS, E. DOBSON, M. DOBSON, J. DODD, O. B. DOGAN, C. DOGLIONI, T. DOHERTY, Y. DOI, J. DOLEJSI, I. DOLENC, Z. DOLEZAL, B. A. DOLGOSHEIN, T. DOHMAE, E. DOMINGO, M. DONEGA, J. DONINI, J. DOPKE, A. DORIA, A. DOS ANJOS, M. DOSIL, A. DOTTI, M. T. DOVA, J. D. DOWELL, A. DOXIADIS, A. T. DOYLE, J. DRAGIC, D. DRAKOULAKOS, Z. DRASAL, J. DREES, N. DRESSNANDT, H. DREVERMANN, C. DRIOUICHI, M. DRIS, J. G. DROHAN, J. DUBBERT, T. DUBBS, E. DUCHOVNI, G. DUCKECK, A. DUDAREV, F. DUDZIAK, M. DUHRSSEN, H. DUR, I. P. DUERDOTH, L. DUFLOT, M. A. DUFOUR, M. DUNFORD, H. DURAN YILDIZ, A. DUSHKIN, R. DUXFIELD, M. DWUZNIK, F. DYDAK, D. DZAHINI, M. DUREN, W. L. EBENSTEIN, J. EBKE, S. ECKERT, S. ECKWEILER, K. EDMONDS, C. A. EDWARDS, I. EFTHYMIOPOULOS, K. EGOROV, W. EHRENFELD, T. EHRICH, T. EIFERT, G. EIGEN, K. EINSWEILER, E. EISENHANDLER, T. EKELOF, M. EL KACIMI, M. ELLERT, S. ELLES, F. ELLINGHAUS, K. ELLIS, N. ELLIS, J. ELMSHEUSER, M. ELSING, R. ELY, D. EMELIYANOV, R. ENGELMANN, A. ENGL, B. EPP, A. EPPIG, J. ERDMANN, A. EREDITATO, V. EREMIN, D. ERIKSSON, I. ERMOLINE, J. ERNST, M. ERNST, J. ERNWEIN, D. ERREDE, S. ERREDE, E. ERTEL, M. ESCALIER, C. ESCOBAR, X. ESPINAL CURULL, B. ESPOSITO, F. ETIENNE, A. I. ETIENVRE, E. ETZION, H. EVANS, V. N. EVDOKIMOV, C. FABRE, K. FACIUS, R. M. FAKHRUTDINOV, S. FALCIANO, A. C. FALOU, Y. FANG, M. FANTI, A. FARBIN, A. FARILLA, J. FARLEY, T. FAROOQUE, S. M. FARRINGTON, P. FARTHOUAT, P. FASSNACHT, D. FASSOULIOTIS, B. FATHOLAHZADEH, L. FAYARD, F. FAYETTE, R. FEBBRARO, P. FEDERIC, O. L. FEDIN, I. FEDORKO, W. FEDORKO, L. FELIGIONI, C. U. FELZMANN, C. FENG, E. J. FENG, A. B. FENYUK, J. FERENCEI, J. FERLAND, B. FERNANDES, W. FERNANDO, S. FERRAG, J. FERRANDO, V. FERRARA, A. FERRARI, P. FERRARI, R. FERRARI, A. FERRER, M. L. FERRER, D. FERRERE, C. FERRETTI, F. FERRO, M. FIASCARIS, S. FICHET, F. FIEDLER, A. FILIPCIC, A. FILIPPAS, F. FILTHAUT, M. FINCKE KEELER, M. C. N. FIOLHAIS, L. FIORINI, A. FIRAN, G. FISCHER, P. FISCHER, M. J. FISHER, S. M. FISHER, H. F. FLACHER, J. FLAMMER, I. FLECK, J. FLECKNER, P. FLEISCHMANN, S. FLEISCHMANN, F. FLEURET, T. FLICK, L. R. FLORES CASTILLO, M. J. FLOWERDEW, F. FOHLISCH, M. FOKITIS, T. FONSECA MARTIN, J. FOPMA, D. A. FORBUSH, A. FORMICA, A. FORTI, D. FORTIN, J. M. FOSTER, D. FOURNIER, A. FOUSSAT, A. J. FOWLER, K. FOWLER, H. FOX, P. FRANCAVILLA, S. FRANCHINO, D. FRANCIS, M. FRANKLIN, S. FRANZ, M. FRATERNALI, S. FRATINA, J. FREESTONE, S. T. FRENCH, R. FROESCHL, D. FROIDEVAUX, J. A. FROST, C. FUKUNAGA, E. FULLANA TORREGROSA, J. FUSTER, C. GABALDON, O. GABIZON, T. 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ZUTSHI, BERTIN, ANTONIO, BINDI, MARCELLO, CAFORIO, DAVIDE, DE CASTRO, STEFANO, DI SIPIO, RICCARDO, FABBRI, LAURA, FRANCHINI, MATTEO, MASSA, IGNAZIO GIACOMO, MENGARELLI, ALBERTO, MONZANI, SIMONE, PICCININI, MAURIZIO, RINALDI, LORENZO, SBARRA, CARLA, SBRIZZI, ANTONIO, SEMPRINI CESARI, NICOLA, VALENTINETTI, SARA, VILLA, MAURO, ZOCCOLI, ANTONIO, Aad, G, Aloisio, Alberto, Alviggi, Mariagrazia, Canale, Vincenzo, Cevenini, F., Chiefari, Giovanni, DELLA VOLPE, Domenico, Merola, Leonardo, Patricelli, Sergio, Conventi, F., DELLA PIETRA, Massimo, Giordano, Raffaele, Musto, E., Rossi, E., Sanchez, A., Carlino, G., de Asmundis, R., Doria, A., Izzo, V., Sekhniaidze, G., UAM. Departamento de Física Teórica, Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire - Clermont-Ferrand (LPC), Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Corpusculaire, Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), ATLAS, Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Abbott, B, Abdallah, J, Abdelalim, Aa, Abdesselam, A, Abdinov, O, Abi, B, Abolins, M, Abramowicz, H, Abreu, H, Acerbi, E, Acharya, B, Adams, Dl, Addy, Tn, Adelman, J, Aderholz, M, Adomeit, S, Adragna, R, Adye, T, Aefsky, S, Aguilar Saavedra, Ja, Aharrouche, M, Ahlen, Sp, Ahles, F, Ahmad, A, Ahsan, M, Aielli, G, Akdogan, T, Akesson, Tpa, Akimoto, G, Akimov, Av, Akiyama, A, Alam, M, Alam, Ma, Albert, J, Albrand, S, Aleksa, M, Aleksandrov, In, Alessandria, F, Alexa, C, Alexander, G, Alexandre, G, Alexopoulos, T, Alhroob, M, Aliev, M, Alimonti, G, Alison, J, Aliyev, M, Allport, Pp, Allwood Spiers, Se, Almond, J, Aloisio, A, Alon, R, Alonso, A, Gonzalez, Ba, Alviggi, Mg, Amako, K, Amaral, P, Amelung, C, Ammosov, Vv, Amorim, A, Amoros, G, Amram, N, Anastopoulos, C, Ancu, L, Andari, N, Andeen, T, Anders, Cf, Anders, G, Anderson, Kj, Andreazza, A, Andrei, V, Andrieux, Ml, Anduaga, X, Angerami, A, Anghinolfi, F, Anjos, N, Annovi, A, Antonaki, A, Antonelli, M, Antonov, A, Antos, J, Anulli, F, Aoun, S, Bella, La, Apolle, R, Arabidze, G, Aracena, I, Arai, Y, Arce, Ath, Archambault, Jp, Arfaoui, S, Arguin, Jf, Arik, E, Arik, M, Armbruster, Aj, Arnaez, O, Arnault, C, Artamonov, A, Artoni, G, Arutinov, D, Asai, S, Asfandiyarov, R, Ask, S, Asman, B, Asquith, L, Assamagan, K, Astbury, A, Astvatsatourov, A, Atoian, G, Aubert, B, Auge, E, Augsten, K, Aurousseau, M, Avolio, G, Avramidou, R, Axen, D, Ay, C, Azuelos, G, Azuma, Y, Baak, Ma, 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S, Zhong, J, Zhou, B, Zhou, N, Zhou, Y, Zhu, Cg, Zhu, H, Zhu, J, Zhu, Y, Zhuang, X, Zhuravlov, V, Zieminska, D, Zimmermann, R, Zimmermann, S, Ziolkowski, M, Zitoun, R, Zivkovic, L, Zmouchko, Vv, Zobernig, G, Zoccoli, A, Zolnierowski, Y, Zsenei, A, zur Nedden, M, Zutshi, V, Zwalinski, L., Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, Universidade do Minho, Współautorami artykułu są członkowie ATLAS Collaboration w liczbie 3004, Massachusetts Institute of Technology. Department of Physics, Taylor, Frank E., G., Aad, Bianco, Michele, G., Chiodini, Gorini, Edoardo, Primavera, Margherita, Spagnolo, Stefania Antonia, Ventura, Andrea, ATLAS Collaboration (ukupan broj autora: 3006), ATLAS (IHEF, IoP, FNWI), G. AAD, E. ABAT, B. ABBOTT, J. ABDALLAH, A.A. ABDELALIM, A. ABDESSELAM, O. ABDINOV, B. ABI, M. ABOLINS, H. ABRAMOWICZ, H. ABREU, E. ACERBI, B.S. ACHARYA, M. ACKERS, D.L. ADAMS, T.N. ADDY, J. ADELMAN, M. ADERHOLZ, C. ADORISIO, P. ADRAGNA, T. ADYE, S. AEFSKY, J.A. AGUILAR-SAAVEDRA, M. AHARROUCHE, S.P. AHLEN, F. AHLES, A. AHMAD, H. AHMED, M. AHSAN, G. AIELLI, T. AKDOGAN, P.F. AKESSON, T.P.A. AKESSON, G. AKIMOTO, A.V. AKIMOV, A. AKTAS, M.S. ALAM, M.A. ALAM, J. ALBERT, S. ALBRAND, M. ALEKSA, I.N. ALEKSANDROV, M. ALEPPO, F. ALESSANDRIA, C. ALEXA, G. ALEXANDER, G. ALEXANDRE, T. ALEXOPOULOS, M. ALHROOB, M. ALIEV, G. ALIMONTI, J. ALISON, M. ALIYEV, P.P. ALLPORT, S.E. ALLWOOD-SPIERS, J. ALMOND, A. ALOISIO, R. ALON, A. ALONSO, J. ALONSO, M.G. ALVIGGI, K. 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VANNUCCI, F. VARELA RODRIGUEZ, R. VARI, E.W. VARNES, D. VAROUCHAS, A. VARTAPETIAN, K.E. VARVELL, L. VASILYEVA, V.I. VASSILAKOPOULOS, F. VAZEILLE, G. VEGNI, J.J. VEILLET, C. VELLIDIS, F. VELOSO, R. VENESS, S. VENEZIANO, A. VENTURA, D. VENTURA, S. VENTURA, M. VENTURI, N. VENTURI, V. VERCESI, M. VERDUCCI, W. VERKERKE, J.C. VERMEULEN, L. VERTOGARDOV, M.C. VETTERLI, I. VICHOU, T. VICKEY, G.H.A. VIEHHAUSER, M. VILLA, E.G. VILLANI, M. VILLAPLANA PEREZ, E. VILUCCHI, P. VINCENT, M.G. VINCTER, E. VINEK, V.B. VINOGRADOV, M. VIRCHAUX, S. VIRET, J. VIRZI, O. VITELLS, I. VIVARELLI, F. VIVES VAQUE, S. VLACHOS, M. VLASAK, N. VLASOV, A. VOGEL, H. VOGT, P. VOKAC, C.F. VOLLMER, M. VOLPI, G. VOLPINI, H. VON DER SCHMITT, J. VON LOEBEN, H. VON RADZIEWSKI, E. VON TOERNE, V. VOROBEL, A.P. VOROBIEV, V. VORWERK, M. VOS, K.C. VOSS, R. VOSS, T.T. VOSS, J.H. VOSSEBELD, A.S. VOVENKO, N. VRANJES, M. VRANJES MILOSAVLJEVIC, V. VRBA, M. VREESWIJK, T. VU ANH, B. VUARIDEL, D. VUDRAGOVIC, R. VUILLERMET, I. VUKOTIC, A. WAANANEN, P. WAGNER, H. WAHLEN, J. WALBERSLOH, J. WALDER, R. WALKER, W. WALKOWIAK, R. WALL, S. WALSH, C. WANG, H. WANG, J. WANG, J.C. WANG, M.W. WANG, S.M. WANG, F. WAPPLER, A. WARBURTON, C.P. WARD, M. WARSINSKY, R. WASTIE, P.M. WATKINS, A.T. WATSON, M.F. WATSON, G. WATTS, S. WATTS, A.T. WAUGH, B.M. WAUGH, M. WEBEL, G. WEBER, J. WEBER, M.D. WEBER, M. WEBER, M.S. WEBER, P. WEBER, A.R. WEIDBERG, J. WEINGARTEN, C. WEISER, H. WELLENSTEIN, H.P. WELLISCH, P.S. WELLS, M. WEN, T. WENAUS, S. WENDLER, T. WENGLER, S. WENIG, N. WERMES, M. WERNER, P. WERNER, M. WERTH, U. WERTHENBACH, M. WESSELS, K. WHALEN, S.J. WHEELER-ELLIS, S.P. WHITAKER, A. WHITE, M.J. WHITE, S. WHITE, S.R. WHITEHEAD, D. WHITESON, D. WHITTINGTON, F. WICEK, D. WICKE, F.J. WICKENS, W. WIEDENMANN, M. WIELERS, P. WIENEMANN, M. WIESMANN, C. WIGLESWORTH, L.A.M. WIIK, A. WILDAUER, M.A. WILDT, I. WILHELM, H.G. WILKENS, E. WILLIAMS, H.H. WILLIAMS, W. WILLIS, S. WILLOCQ, J.A. WILSON, M.G. WILSON, A. WILSON, I. WINGERTER-SEEZ, F. WINKLMEIER, M. WITTGEN, E. WOEHRLING, M.W. WOLTER, H. WOLTERS, B.K. WOSIEK, J. WOTSCHACK, M.J. WOUDSTRA, K. WRAIGHT, C. WRIGHT, D. WRIGHT, B. WRONA, S.L. WU, X. WU, J. WUESTENFELD, E. WULF, R. WUNSTORF, B.M. WYNNE, L. XAPLANTERIS, S. XELLA, S. XIE, Y. XIE, D. XU, G. XU, N. XU, M. YAMADA, A. YAMAMOTO, K. YAMAMOTO, S. YAMAMOTO, T. YAMAMURA, J. YAMAOKA, T. YAMAZAKI, Y. YAMAZAKI, Z. YAN, H. YANG, S. YANG, U.K. YANG, Y. YANG, Z. YANG, W.-M. YAO, Y. YAO, K. YARRADODDI, Y. YASU, J. YE, S. YE, M. YILMAZ, R. YOOSOOFMIYA, K. YORITA, H. YOSHIDA, R. YOSHIDA, C. YOUNG, S.P. YOUSSEF, D. YU, J. YU, J. YUAN, L. YUAN, A. YURKEWICZ, V.G. ZAETS, R. ZAIDAN, A.M. ZAITSEV, Z. ZAJACOVA, YO.K. ZALITE, V. ZAMBRANO, L. ZANELLO, P. ZARZHITSKY, A. ZAYTSEV, M. ZDRAZIL, C. ZEITNITZ, M. ZELLER, P.F. ZEMA, A. ZEMLA, C. ZENDLER, A.V. ZENIN, O. ZENIN, T. ZENIS, Z. ZENONOS, S. ZENZ, D. ZERWAS, G. ZEVI DELLA PORTA, Z. ZHAN, H. ZHANG, J. ZHANG, Q. ZHANG, X. ZHANG, L. ZHAO, T. ZHAO, Z. ZHAO, A. ZHEMCHUGOV, S. ZHENG, J. ZHONG, B. ZHOU, N. ZHOU, Y. ZHOU, C.G. ZHU, H. ZHU, Y. ZHU, X. ZHUANG, V. ZHURAVLOV, B. ZILKA, R. ZIMMERMANN, S. ZIMMERMANN, M. ZIOLKOWSKI, R. ZITOUN, L. ZIVKOVIC, V.V. ZMOUCHKO, G. ZOBERNIG, A. ZOCCOLI, Y. ZOLNIEROWSKI, A. ZSENEI, M. ZUR NEDDEN, and V. ZUTSHI
Subjects: high-energy collider experiment, cross-section, Top quark, Physics::Instrumentation and Detectors, Atlas detector, top physics, Hadron, High-energy collider experiment, Electron, 01 natural sciences, 7. Clean energy, Settore FIS/04 - Fisica Nucleare e Subnucleare, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], Nuclear Experiment, QC, Detectors de radiació, Physics, Quantum chromodynamics, Atlas (topology), Settore FIS/01 - Fisica Sperimentale, ATLAS, Top physics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, LHC, Particle Physics - Experiment, Nuclear and High Energy Physics, Particle physics, Cross-section, Ciências Naturais::Ciências Físicas, Ciências Físicas [Ciências Naturais], FOS: Physical sciences, TOP QUARK, Partícules (Física nuclear), Nuclear physics, 0103 physical sciences, ddc:530, High Energy Physics, 010306 general physics, Science & Technology, PP COLLISIONS, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Física, Pair production, HADRON-HADRON COLLISIONS, Col·lisions (Física nuclear), Experimental High Energy Physics, TEV, High Energy Physics::Experiment, Lepton
Abstract: A measurement of the production cross-section for top quark pairs (t[bar over t]) in pp collisions at √s = 7 TeV is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in the single lepton topology by requiring an electron or muon, large missing transverse momentum and at least three jets. With a data sample of 35 pb[superscript −1], two different multivariate methods, one of which uses b-quark jet identification while the other does not, use kinematic variables to obtain cross-section measurements of σ[subscript t bar over t] = 187 ± 11 (stat.) [+18 over −17] (syst.) ± 6 (lumi.) pb and σ[subscript t bar over t] = 173 ± 17 (stat.) [+18 over −16] (syst.) ±6 (lumi.) pb respectively. The two measurements are in agreement with each other and with QCD calculations. The first measurement has a better a priori sensitivity and constitutes the main result of this Letter., European Organization for Nuclear Research, United States. Dept. of Energy, National Science Foundation (U.S.), Brookhaven National Laboratory
Published: 2012

17. Evaluation of the Microbiology of Removed Punctal Plugs and Intracanalicular Devices.

Author: Meyer JJ, Culbreath K, Ager E, Esmaili N, Fowler WC, Gilligan P, and Fowler AM
Abstract: Objective: The purpose of this observational study was to characterize the microorganisms colonizing punctal plugs and intracanalicular stents., Methods: Devices were removed from participants who previously underwent placement of punctal plugs for tear insufficiency and lacrimal stents for dacryocystorhinostomy and canalicular reconstruction procedures. After removal of the devices, they were cultured for organisms both with and without sonication to loosen any biofilms or adherent microorganisms. Primary outcome measures included culture positivity, identification of isolated microorganisms, recovery of microorganisms from culture after sonication, and clinical evidence of ocular infection., Results: There were no cases of clinical infection. A total of 181 specimens were processed (174 punctal plugs, seven intracanalicular stents), of which 98 (54%) were culture positive. Of the punctal plugs, 92 (52.9%) were culture positive, including 42 with a single organism isolated, whereas 22 yielded two organisms, 7 yielded three organisms, and the remaining 21 yielded a polymicrobial culture with four or more organisms. The most common isolates from punctal plugs were coagulase negative staphylococci (27.6%), diphtheroids (16.4%), and streptococcus viridans (10.2%). Those plugs with polymicrobial culture results grew a mixture of organisms most consistent with skin or upper respiratory flora. Of the intracanalicular stents, 6 (85.6%) were culture positive., Conclusions: Punctal plugs and intracanalicular devices can become colonized with bacteria composed of oropharyngeal flora, skin flora, and other rare but potentially significant pathogens., Competing Interests: The author has no funding or conflicts of interest to disclose., (Copyright © 2024 Contact Lens Association of Ophthalmologists.)
Published: 2024
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18. Herpes Zoster Ophthalmicus Uveitis: Onset and Complications.

Author: Meyer JJ, Liu K, Danesh-Meyer HV, and Niederer RL
Abstract: Purpose: To describe the timing of uveitis onset and frequency of associated complications in individuals with herpes zoster ophthalmicus (HZO)., Design: Retrospective, cohort study., Methods: Individuals with acute HZO seen at the Auckland District Health Board from 2006 to 2016 were studied. The primary outcome measures were the proportion who developed uveitis and time to diagnosis of uveitis following the onset of HZO. Secondary outcome measures included complications of HZO uveitis and effects of prompt antiviral (within 72 hours) on outcomes., Results: A total of 869 patients with HZO were included for analysis, of whom 413 (47.6%) developed uveitis. Median time from onset of rash to diagnosis of uveitis was 10 days (IQR 6-14). Of the 658 individuals examined within the first week following rash onset (days 0 through 7), 17.6% (116/658) were diagnosed with uveitis at that initial presenting examination, with an additional 24.9% (164/658) diagnosed with uveitis at a subsequent visit. Complications were higher in eyes with uveitis, including moderate or severe vision loss, corneal scarring, neurotrophic keratitis, band keratopathy, corneal melt, elevated intraocular pressure, glaucoma, and cataract (all P < .01). Prompt antiviral was associated with a lower rate of moderate vision loss among eyes with uveitis (P = .02)., Conclusions: Uveitis occurred in approximately half of individuals with HZO and was most frequently diagnosed during the second week following rash onset. Eyes with uveitis were more likely to have other ocular complications and loss of vision., (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.)
Published: 2024
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19. Mortality and Causes of Death Among Individuals With Keratoconus.

Author: Meyer JJ, Meeks H, Li K, Guinto E, and Olson RJ
Subjects: Humans, Male, Female, Retrospective Studies, Adult, Case-Control Studies, Middle Aged, Utah epidemiology, Risk Factors, Young Adult, Follow-Up Studies, Adolescent, Aged, Proportional Hazards Models, Keratoconus mortality, Cause of Death trends
Abstract: Purpose: The purpose of this study was to determine whether there is an increased risk of mortality among individuals with keratoconus., Methods: This was a retrospective, case-control study using the Utah Population Database. Cases were defined as individuals diagnosed with keratoconus from 1996 to 2020 and were matched 5:1 with controls on birth year, sex, whether born in Utah, and follow-up time in Utah. Individuals diagnosed with trisomy 21 or connective tissue disease were excluded. Main outcome measures were the all-cause and cause-specific mortality among keratoconus cases compared with matched controls. Cox regression models were used, additionally adjusting for race and ethnicity., Results: A total of 7847 keratoconus cases and 38,597 controls were studied in the final analyses. The mean age at index diagnosis was 43 ± 17 years, and mean age at last follow-up was 54 ± 17 years for both cases and controls. At last follow-up, 92% of cases were living compared with 91% of controls. After adjusting for covariates, there were no significant differences in all-cause mortality ( P = 0.161), mortality from natural causes (0.222), or mortality from unnatural causes ( P = 0.494) between cases and controls. When analyzed according to specific causes of death, keratoconus cases had a higher mortality risk from diseases of the nervous system and sense organs compared with their matching controls (hazard ratio 1.59; 95% confidence interval, 1.19-2.11; P = 0.002)., Conclusions: There was no evidence of an increased risk of mortality among individuals with keratoconus. There may be an increased risk of death due to diseases of the nervous system and sense organs among individuals with keratoconus., Competing Interests: The authors have no funding or conflicts of interest to disclose., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Published: 2024
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20. Predictive performance of corneal and lid margin sensitivity for dry eye disease: An investigator-masked, prospective, prognostic accuracy study.

Author: Wang MTM, Meyer JJ, Xue AL, Power B, and Craig JP
Subjects: Humans, Prospective Studies, Female, Male, Middle Aged, Prognosis, Eyelids physiopathology, Eyelids pathology, Adult, Aged, Predictive Value of Tests, Dry Eye Syndromes diagnosis, Dry Eye Syndromes physiopathology, Dry Eye Syndromes metabolism, Cornea pathology, Tears physiology, Tears metabolism
Abstract: Purpose: To evaluate the prognostic ability of non-contact esthesiometry corneal and lid margin sensitivity measurements in detecting symptoms and signs of dry eye disease, as defined by the global consensus TFOS DEWS II criteria., Methods: A total of 87 community residents (58 females; mean ± SD age, 53 ± 16 years) were recruited in an investigator-masked, prospective, prognostic accuracy study. Dry eye symptomology, tear film parameters, and ocular surface characteristics were evaluated in a single clinical session, and non-contact esthesiometry corneal and lid margin sensitivity measurements performed by an independent masked assessor., Results: Overall, 49 (56%) participants fulfilled the TFOS DEWS II criteria for dry eye disease, while 57 (66%) exhibited clinical symptoms, and 67 (77%) had positive signs. The prognostic abilities of corneal and lid margin sensitivity measurements were significantly greater than chance for the detection dry eye signs (both p ≤ 0.03), but not for symptoms or overall disease diagnosis (all p > 0.10). The Youden-optimal prognostic cut-offs for corneal and lid margin sensitivity thresholds were both ≥0.8 mbar for the detection of clinical dry eye signs. Lid margin sensitivity demonstrated marginally higher predictive performance than corneal sensitivity (C-statistic, 0.688 versus 0.658), and was significantly correlated with tear film stability, corneal, conjunctival and lid wiper staining (all p < 0.05)., Conclusions: Corneal and lid margin sensitivity demonstrated moderate prognostic utility for detecting clinical dry eye signs. Future research is warranted to investigate the utility of incorporating non-contact esthesiometry in the workup for dry eye disease and neurotrophic keratopathy., Competing Interests: Declaration of competing interest The authors have no commercial or proprietary interest in any concept or product described in this article., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
Published: 2024
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21. Chemical eye injuries: a 10 year retrospective review of acute presentations and clinical outcomes in Auckland, New Zealand.

Author: Allen NE, Crawford AZ, McGhee CNJ, and Meyer JJ
Subjects: Humans, Male, Young Adult, Adult, Middle Aged, Female, Retrospective Studies, New Zealand epidemiology, Vision Disorders, Eye Burns, Endophthalmitis, Burns, Chemical, Eye Injuries epidemiology, Eye Injuries etiology, Eye Injuries therapy
Abstract: To assess the aetiologies, clinical characteristics, treatment regimens, and outcomes of acute chemical injuries treated at an emergency eye clinic. Retrospective, observational study of all cases of chemical eye injury that presented acutely to the Greenlane Clinical Centre in Auckland, New Zealand from 1 January 2012 through 31 December 2021. Patient demographics, activity at the time of injury, causative chemical, clinical characteristics of injury at presentation, severity (Dua) classification, admission and discharge best corrected visual acuity (BCVA), treatment regimen, time to epithelisation and number of follow-up appointments were recorded. In total, 1522 cases involving 1919 eyes were studied. The mean age was 40.6 ± 18.8 years and 65% were male. The majority of cases occurred at home (62%) and cleaning was the most common activity (38%). There were 1490 Grade I (98%), 22 Grade II (1.5%), 5 Grade III (0.3%), 1 Grade IV (0.07%), 0 Grade V, and 4 Grade VI (0.3%) cases. An epithelial defect was noted in 409 cases (26.9%), of which re-epithelialisation occurred within one week for 378 cases (92%) and within 30 days for 384 cases (94%). Moderate vision loss (BCVA ≤ 6/12) attributed to the injury occurred in 152 (10%), while severe vision loss (BCVA ≤ 6/60) occurred in 30 (2%). Lack of irrigation at the scene was associated with an increased risk of severe injury and longstanding visual impairment (p = 0.0001). Most acute chemical injuries are mild with good clinical outcomes. Although rare, severe injuries are associated with a lack of irrigation at the scene and worse visual outcomes., (© 2024. The Author(s).)
Published: 2024
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22. Design and Construction of a Multi-Tiered Minimal Actin Cortex for Structural Support in Lipid Bilayer Applications.

Author: Smith AJ, Larsen TRB, Zimmerman HK, Virolainen SJ, Meyer JJ, Keranen Burden LM, and Burden DL
Subjects: Cell Membrane, Cytoskeleton, Actin Cytoskeleton, Lipid Bilayers, Actins
Abstract: Artificial lipid bilayers have revolutionized biochemical and biophysical research by providing a versatile interface to study aspects of cell membranes and membrane-bound processes in a controlled environment. Artificial bilayers also play a central role in numerous biosensing applications, form the foundational interface for liposomal drug delivery, and provide a vital structure for the development of synthetic cells. But unlike the envelope in many living cells, artificial bilayers can be mechanically fragile. Here, we develop prototype scaffolds for artificial bilayers made from multiple chemically linked tiers of actin filaments that can be bonded to lipid headgroups. We call the interlinked and layered assembly a multiple minimal actin cortex (multi-MAC). Construction of multi-MACs has the potential to significantly increase the bilayer's resistance to applied stress while retaining many desirable physical and chemical properties that are characteristic of lipid bilayers. Furthermore, the linking chemistry of multi-MACs is generalizable and can be applied almost anywhere lipid bilayers are important. This work describes a filament-by-filament approach to multi-MAC assembly that produces distinct 2D and 3D architectures. The nature of the structure depends on a combination of the underlying chemical conditions. Using fluorescence imaging techniques in model planar bilayers, we explore how multi-MACs vary with electrostatic charge, assembly time, ionic strength, and type of chemical linker. We also assess how the presence of a multi-MAC alters the underlying lateral diffusion of lipids and investigate the ability of multi-MACs to withstand exposure to shear stress.
Published: 2024
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23. Defining Minimum Treatment Parameters of Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma: An Expert Consensus.

Author: Yanagihara TK, Tepper JE, Moon AM, Barry A, Molla M, Seong J, Torres F, Apisarnthanarax S, Buckstein M, Cardenes H, Chang DT, Feng M, Guha C, Hallemeier CL, Hawkins MA, Hoyer M, Iwata H, Jabbour SK, Kachnic L, Kharofa J, Kim TH, Kirichenko A, Koay EJ, Makishima H, Mases J, Meyer JJ, Munoz-Schuffenegger P, Owen D, Park HC, Saez J, Sanford NN, Scorsetti M, Smith GL, Wo JY, Yoon SM, Lawrence TS, Reig M, and Dawson LA
Subjects: Humans, Consensus, Ambulatory Care Facilities, Carbon, Carcinoma, Hepatocellular radiotherapy, Liver Neoplasms radiotherapy
Abstract: Purpose: External beam radiation therapy (EBRT) is a highly effective treatment in select patients with hepatocellular carcinoma (HCC). However, the Barcelona Clinic Liver Cancer system does not recommend the use of EBRT in HCC due to a lack of sufficient evidence and intends to perform an individual patient level meta-analysis of ablative EBRT in this population. However, there are many types of EBRT described in the literature with no formal definition of what constitutes "ablative." Thus, we convened a group of international experts to provide consensus on the parameters that define ablative EBRT in HCC., Methods and Materials: Fundamental parameters related to dose, fractionation, radiobiology, target identification, and delivery technique were identified by a steering committee to generate 7 Key Criteria (KC) that would define ablative EBRT for HCC. Using a modified Delphi (mDelphi) method, experts in the use of EBRT in the treatment of HCC were surveyed. Respondents were given 30 days to respond in round 1 of the mDelphi and 14 days to respond in round 2. A threshold of ≥70% was used to define consensus for answers to each KC., Results: Of 40 invitations extended, 35 (88%) returned responses. In the first round, 3 of 7 KC reached consensus. In the second round, 100% returned responses and consensus was reached in 3 of the remaining 4 KC. The distribution of answers for one KC, which queried the a/b ratio of HCC, was such that consensus was not achieved. Based on this analysis, ablative EBRT for HCC was defined as a BED10 ≥80 Gy with daily imaging and multiphasic contrast used for target delineation. Treatment breaks (eg, for adaptive EBRT) are allowed, but the total treatment time should be ≤6 weeks. Equivalent dose when treating with protons should use a conversion factor of 1.1, but there is no single conversion factor for carbon ions., Conclusions: Using a mDelphi method assessing expert opinion, we provide the first consensus definition of ablative EBRT for HCC. Empirical data are required to define the a/b of HCC., Competing Interests: Disclosures Ted K. Yanagihara reports grants or contracts from the Radiation Oncology Institute and Lineberger Comprehensive Cancer Center; serving as an expert independent reviewer for the North Carolina Medical Board; and serving as an American Board of Radiology Maintenance of Certification online longitudinal assessment senior reviewer. Andrew M. Moon reports grants or contracts from the American Association for the Study of Liver Diseases, the American College of Gastroenterology, and the National Institutes of Health; consulting feeds from Target RWE; and serving on the American Association for the Study of Liver Diseases Practice Guidelines Committee. Aisling Barry reports honoria from Eisai. Ferran Torres reports grants or contracts from the Hospital Clinic Barcelona (IDIBAPS); consulting fees from Universal DX; and participation in the data safety monitoring board/advisory board of the Hospital Clinic Barcelona with partial support from Bayer. Daniel T. Chang reports grants or contracts from RefleXion Medical, ViewRay, Inc, Varian Medical Systems; honoraria for presentation from Varian Medical Systems; support for attending meetings and travel from Varian Medical Systems; and participation on data safety monitoring board for the SMART trial for ViewRay. Chandan Guha reports grants or contracts from the NIH, Janssen and Celldex; consulting fees from Janssen; participation in the data safety monitoring board or advisory board of the Focused Ultrasound Foundation; and is a founder of BioConvergent Health. Morten Hoyer reports honoraria from Novo Nordisk. Lisa Kachnic reports receiving grants or contracts from Varian Medical Systems; serving as an editor for UpToDate; participation on the data safety monitoring committee for Beta Innovations; and is a board member of the Radiation Therapy Oncology Group. Eugene J. Koay reports funding from the Department of Defense and National Institutes of Health; grants or contracts from Philips Healthcare, GE Healthcare, Stand up to Cancer, Project Purple, Elekta, Department of Defense; royalties from Taylor and Francis, LLC; consulting fees from RenovoRx, AstraZeneca, Augmenix, and Kallisio; honoraria for lectures from Apollo Cancer hospitals in Chnnai India, Bayer Healthcare, Philips Healthcare, and Aptitude Health; a patent pending for 3-dimensional printed oral stents; serving on the scientific medical advisory board of the International Cholangiocarcinoma Research Network; and stock ownership of Quantum Aurea Capital. Joel Mases reports grants or contracts from Boston Scientific and royalties or licenses from Springer and UpToDate. Pablo Munoz-Schuffenegger reports grants or contracts from the National Fund for Scientific and Technological Development, National Commission for Scientific and Technological Research, Government of Chile; honoraria for lectures from Bayer and Roche Pharma AG; serving on an advisory board for AstraZeneca; and serving on the advanced radiation therapy committee, International Association for the Study of Lung Cancer. Dawn Owen reports payment from UpToDate and receipt of goods/services from AstraZeneca and Varian Medical Systems. Marta Scorsetti reports grants or contracts from Varian Medical Systems, Sofar, and IPSEN. Jenniefer Y. Wo reports grants or contracts from Genentech. Maria Reig reports grants or contracts from Bayer, Ipsen, and ISCII; serving as a consultant or on advisory boards and/or receiving travel support from Bayer, BMS, Roche, Ipsen, AstraZeneca, Eisai, Geneos Therapeutics, UniveralDx, MSD and Lilly; receiving lecture fees from Bayer, BMS, Gilead, AstraZeneca, ROCHE and Lilly; receiving support for attending meetings and/or travel from Bayer, BMS, Roche, Ipsen, AstraZeneca, Eisai, MSD, and Lilly; and serving as EASL representative in UEG. Laura A. Dawson reports serving as chair of ASTRO., (Copyright © 2023. Published by Elsevier Inc.)
Published: 2024
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24. Comment on: A Systematic Review and Meta-Analysis of Systemic Antihypertensive Medications with Intraocular Pressure and Glaucoma.

Author: Meyer JJ
Subjects: Humans, Intraocular Pressure, Antihypertensive Agents therapeutic use, Tonometry, Ocular, Glaucoma drug therapy, Ocular Hypertension drug therapy
Published: 2024
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25. Exponentially tighter bounds on limitations of quantum error mitigation.

Author: Quek Y, Stilck França D, Khatri S, Meyer JJ, and Eisert J
Abstract: Quantum error mitigation has been proposed as a means to combat unwanted and unavoidable errors in near-term quantum computing without the heavy resource overheads required by fault-tolerant schemes. Recently, error mitigation has been successfully applied to reduce noise in near-term applications. In this work, however, we identify strong limitations to the degree to which quantum noise can be effectively 'undone' for larger system sizes. Our framework rigorously captures large classes of error-mitigation schemes in use today. By relating error mitigation to a statistical inference problem, we show that even at shallow circuit depths comparable to those of current experiments, a superpolynomial number of samples is needed in the worst case to estimate the expectation values of noiseless observables, the principal task of error mitigation. Notably, our construction implies that scrambling due to noise can kick in at exponentially smaller depths than previously thought. Noise also impacts other near-term applications by constraining kernel estimation in quantum machine learning, causing an earlier emergence of noise-induced barren plateaus in variational quantum algorithms and ruling out exponential quantum speed-ups in estimating expectation values in the presence of noise or preparing the ground state of a Hamiltonian., Competing Interests: Competing interestsThe authors declare no competing interests., (© The Author(s) 2024.)
Published: 2024
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26. Cytoreductive single-fraction stereotactic radiation therapy prior to living donor transplantation for inoperable liver-confined metastatic rectal cancer.

Author: Papanikolaou PA, Wesson RN, Azad NS, and Meyer JJ
Abstract: Competing Interests: Authors’ disclosure of potential conflicts of interest Jeffrey Meyer receives royalties from Springer, UpToDate, and sponsored research support from Boston Scientific. The other authors have nothing to disclose.
Published: 2024

27. Keratoconus in Down syndrome: Prevalence, risk factors, severity and corneal tomographic characteristics.

Author: Mathan JJ, Gokul A, Simkin SK, Meyer JJ, and McGhee CNJ
Subjects: Child, Humans, Cornea diagnostic imaging, Corneal Pachymetry, Corneal Topography methods, Prevalence, Risk Factors, Tomography, Prospective Studies, Down Syndrome complications, Down Syndrome diagnosis, Down Syndrome epidemiology, Keratoconus complications, Keratoconus diagnosis, Keratoconus epidemiology
Abstract: Background: This study investigated the prevalence, risk factors and severity of corneal tomographic features of keratoconus in Down syndrome (DS). Additionally, previous studies indicate anomalous corneal features in DS, without keratoconus, this study characterised corneal features in DS without keratoconus., Methods: This prospective observational study included participants with DS ≥10 years old. Keratoconus diagnosis, risk factors and corneal tomographic characteristics were recorded. Participants underwent slit-lamp biomicroscopy, Scheimpflug corneal tomography, corneal topography and autorefraction. A diagnosis of keratoconus (DS-KC), suspect keratoconus (DS-SK) and non-keratoconus (DS-NK) was made based on expert review of scans by three fellowship trained anterior segment ophthalmologists. Corneal tomography parameters from one eye of each participant were analysed., Results: Keratoconus affected 50 (26.3%) of 190 participants, diagnosed by corneal tomography, topography or slit-lamp signs. Corneal hydrops affected 14.0% of DS-KC participants. Eye rubbing was a significant risk factor for keratoconus (p = 0.036). 175 (92%) participants could undertake corneal tomography of which tomography assessment alone identified 47 (26.9%) DS-KC participants, 64 (36.6%) DS-SK participants and 64 (36.6%) DS-NK participants. Significant differences (p < 0.001) were identified when the DS-KC, DS-SK and DS-NK groups were compared in maximum keratometry and posterior elevation at the thinnest point respectively: median (interquartile range) 50.20 (10.30D), 47.60 (1.95D), 46.50 (2.40D); 24.0 (38.00 μm), 10.00 (13.75 μm), 8.00 (6.00 μm). The DS-SK and DS-NK cohorts had similar minimum pachymetry, however, had several significantly different parameters among which included greater maximum keratometry, posterior elevation at the thinnest point in the DS-SK group., Conclusions: Keratoconus is common in DS. Keratoconus screening with corneal tomography is recommended for early detection., (© 2023 The Authors. Clinical & Experimental Ophthalmology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Ophthalmologists.)
Published: 2024
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28. Patterns and kinetics of hepatocellular carcinoma relapse post-liver transplantation: oligorecurrence and role of local therapies.

Author: Lin TA, Paul N, Luu H, Cheung D, Saberi B, Ottmann S, Gurakar A, Yarchoan M, Narang A, Kim A, and Meyer JJ
Abstract: Background: Amongst patients with recurrent hepatocellular carcinoma (HCC) post-liver transplantation, systemic therapy options may be limited by immunosuppression or poor performance status. Thus, we aimed to assess the impact of metastasis-directed therapy to all sites of disease (MDT-All) in HCC patients with limited disease recurrence [i.e., oligorecurrence (oligoM1)] post-transplantation and characterize pre-transplant characteristics associated with oligoM1., Methods: In this retrospective cohort study, patients at a single institution with recurrent HCC post-liver transplantation were identified. OligoM1 disease was defined as ≤3 lesions at recurrence, while polyrecurrent (polyM1) disease was defined as >3 lesions. Outcomes were compared in patients with oligoM1 disease by receipt of MDT-All. Regression analyses were used to identify predictors of polyM1 disease and characteristics associated with post-recurrence outcomes., Results: Forty-three patients with recurrent HCC post-liver transplantation from 2005-2022 were identified. Twenty-seven (63%) patients had oligoM1. Microvascular invasion was independently associated with polyM1 [odds ratio (OR): 14.64; 95% confidence interval (CI): 1.48-144.77; P=0.022]. Elevated alpha-fetoprotein (AFP) ≥400 ng/mL [hazard ratio (HR): 2.44; 95% CI: 1.08, 5.52; P=0.033] at recurrence was independently associated with inferior overall survival (OS), while oligoM1 (HR: 0.42; 95% CI: 0.21, 0.87; P=0.018) was independently associated with favorable OS. Amongst patients with oligoM1 who received MDT-All (n=15) median OS was 38.4 vs. 16.1 months for those who did not receive MDT-All (log-rank P=0.021). There was a non-significant improvement in polyprogression-free survival (polyPFS) (median 14.0 vs. 10.7 months, P=0.1) amongst oligoM1 patients who received MDT-All compared to those who did not., Conclusions: Receipt of MDT-All was associated with improved OS amongst patients with limited HCC disease recurrence following liver transplantation., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jgo.amegroups.com/article/view/10.21037/jgo-23-541/coif). A.K. previously received consulting fees from AstraZeneca. J.J.M. receives royalties from UpToDate and Springer and previously received research support from Boston Scientific (funds paid to institution). The other authors have no conflicts of interest to declare., (2023 Journal of Gastrointestinal Oncology. All rights reserved.)
Published: 2023
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29. Confirming Silent Translocation through Nanopores with Simultaneous Single-Molecule Fluorescence and Single-Channel Electrical Recordings.

Author: Burden DL, Meyer JJ, Michael RD, Anderson SC, Burden HM, Peña SM, Leong-Fern KJ, Van Ye LA, Meyer EC, and Keranen-Burden LM
Subjects: Fluorescence, Nanotechnology, Electricity, Ion Transport, Nanopores
Abstract: Most of what is known concerning the luminal passage of materials through nanopores arises from electrical measurements. Whether nanopores are biological, solid-state, synthetic, hybrid, glass-capillary-based, or protein ion channels in cells and tissues, characteristic signatures embedded in the flow of ionic current are foundational to understanding functional behavior. In contrast, this work describes passage through a nanopore that occurs without producing an electrical signature. We refer to the phenomenon as "silent translocation." By definition, silent translocations are invisible to the standard tools of electrophysiology and fundamentally require a simultaneous ancillary measurement technique for positive identification. As a result, this phenomenon has been largely unexplored in the literature. Here, we report on a derivative of Cyanine 5 (sCy5a) that passes through the α-hemolysin (αHL) nanopore silently. Simultaneously acquired single-molecule fluorescence and single-channel electrical recordings from bilayers formed over a closed microcavity demonstrate that translocation does indeed take place, albeit infrequently. We report observations of silent translocation as a function of time, dye concentration, and nanopore population in the bilayer. Lastly, measurement of the translocation rate as a function of applied potential permits estimation of an effective energy barrier for transport through the pore as well as the effective charge on the dye, all in the absence of an information-containing electrical signature.
Published: 2023
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30. Comparison of Ectasia Detection in Early Keratoconus Using Scheimpflug-Based Corneal Tomography and Biomechanical Assessments.

Author: Wallace HB, Vellara HR, Gokul A, McGhee CNJ, and Meyer JJ
Subjects: Humans, Corneal Topography methods, Dilatation, Pathologic diagnosis, Corneal Pachymetry, Retrospective Studies, Cornea, ROC Curve, Tomography, Biomechanical Phenomena, Keratoconus diagnosis
Abstract: Purpose: The aim of this study was to determine the detection of keratoconus using corneal biomechanical parameters only, a corneal tomographic parameter only, and a parameter that combines corneal biomechanical and tomographic indices., Methods: The discriminatory power of the Pentacam Random Forest Index (PRFI), Belin/Ambrósio Enhanced Ectasia Display (BAD-D) index, Corvis Biomechanical Index (CBI), and Tomographic and Biomechanical Index (TBI) to differentiate between normal eyes (n = 84), eyes with very asymmetric corneal ectasia (VAE-E, n = 21), and the fellow eyes without apparent ectasia based on normal tomography (VAE-NT, n = 21) was assessed. Statistical analyses were completed with R software using t -tests, Wilcoxon rank sum tests, and receiver operating characteristic (ROC) curves. The DeLong test was used to compare the area under the ROC curve (AUROC)., Results: The TBI and PRFI had the highest AUROC when distinguishing between normal and VAE-E corneas (AUROC = 1.00, 95% CI = 1.00-1.00); however, they were not statistically superior to the CBI (AUROC = 0.97, P = 0.27) or BAD-D (AUROC = 1.00, P = 0.34). The TBI (AUROC = 0.92, 95% CI = 0.86-0.98) was superior to CBI (AUROC = 0.78, P = 0.02) and BAD-D (AUROC = 0.81, P = 0.02) when distinguishing between healthy and VAE-NT corneas. At a threshold of 0.72, the TBI had 99% sensitivity, 67% specificity, and 92% accuracy in distinguishing normal and VAE-NT corneas., Conclusions: The TBI is a useful parameter for the screening of subclinical and frank keratoconus in tomographically normal eyes., Competing Interests: The authors have no funding or conflicts of interest to disclose., (Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.)
Published: 2023
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31. Classical Surrogates for Quantum Learning Models.

Author: Schreiber FJ, Eisert J, and Meyer JJ
Abstract: The advent of noisy intermediate-scale quantum computers has put the search for possible applications to the forefront of quantum information science. One area where hopes for an advantage through near-term quantum computers are high is quantum machine learning, where variational quantum learning models based on parametrized quantum circuits are discussed. In this work, we introduce the concept of a classical surrogate, a classical model which can be efficiently obtained from a trained quantum learning model and reproduces its input-output relations. As inference can be performed classically, the existence of a classical surrogate greatly enhances the applicability of a quantum learning strategy. However, the classical surrogate also challenges possible advantages of quantum schemes. As it is possible to directly optimize the Ansatz of the classical surrogate, they create a natural benchmark the quantum model has to outperform. We show that large classes of well-analyzed reuploading models have a classical surrogate. We conducted numerical experiments and found that these quantum models show no advantage in performance or trainability in the problems we analyze. This leaves only generalization capability as a possible point of quantum advantage and emphasizes the dire need for a better understanding of inductive biases of quantum learning models.
Published: 2023
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32. Selective de-implementation of routine in vivo dosimetry.

Author: Mao SPH, Han-Oh S, Moore J, Huang E, McNutt TR, Souranis AN, Briner V, Halthore A, Alcorn SR, Meyer JJ, Viswanathan AN, and Wright JL
Subjects: Humans, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted methods, Electrons, Radiometry methods, In Vivo Dosimetry, Radiotherapy, Conformal methods
Abstract: As cone-beam computed tomography (CBCT) has become the localization method for a majority of cases, the indications for diode-based confirmation of accurate patient set-up and treatment are now limited and must be balanced between proper resource allocation and optimizing efficiency without compromising safety. We undertook a de-implementation quality improvement project to discontinue routine diode use in non-intensity modulated radiotherapy (IMRT) cases in favor of tailored selection of scenarios where diodes may be useful. After analysis of safety reports from the last 5 years, literature review, and stakeholder discussions, our safety and quality (SAQ) committee introduced a recommendation to limit diode use to specific scenarios in which in vivo verification may add value to standard quality assurance (QA) processes. To assess changes in patterns of use, we reviewed diode use by clinical indication 4 months prior and after the implementation of the revised policy, which includes use of diodes for: 3D conformal photon fields set up without CBCT; total body irradiation (TBI); electron beams; cardiac devices within 10 cm of the treatment field; and unique scenarios on a case-by-case basis. We identified 4459 prescriptions and 1038 unique instances of diode use across five clinical sites from 5/2021 to 1/2022. After implementation of the revised policy, we observed an overall decrease in diode use from 32% to 13.2%, with a precipitous drop in 3D cases utilizing CBCT (from 23.2% to 4%), while maintaining diode utilization in the 5 selected scenarios including 100% of TBI and electron cases. By identifying specific indications for diode use and creating a user-friendly platform for case selection, we have successfully de-implemented routine diode use in favor of a selective process that identifies cases where the diode is important for patient safety. In doing so, we have streamlined patient care and decreased cost without compromising patient safety., (© 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.)
Published: 2023
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33. Progression of keratoconus in children and adolescents.

Author: Meyer JJ, Gokul A, Vellara HR, and McGhee CNJ
Subjects: Humans, Adolescent, Child, Corneal Topography methods, Retrospective Studies, Cohort Studies, Cornea, Corneal Pachymetry, Disease Progression, Keratoconus diagnosis, Keratoconus epidemiology
Abstract: Aims: To evaluate the rates of keratoconus progression and associated factors in eyes of children and adolescents., Methods: Retrospective, cohort study of individuals ≤18 years old at the time of keratoconus diagnosis and with at least 6 months of follow-up. Corneal tomography was performed using an Orbscan tomographer (Bausch & Lomb, Rochester, New York, USA) to determine whether progression occurred. Tomographic progression of keratoconus was defined as a change in any of the investigated parameters (keratometry values, K MAX , maximum anterior or posterior elevation, central pachymetry, thinnest pachymetry) beyond the limits of repeatability., Results: 148 eyes of 106 patients with a mean age of 15.2±2.5 years were studied over a mean follow-up period of 2.9±2.2 years. The overall rate of tomographic progression was 77.0% (114/148 eyes). Eyes that progressed had more advanced disease at presentation with higher anterior curvature (K MAX 55.4±6.3 vs 52.2±5.4 dioptres; p<0.01), posterior elevation (108.2±40.9 vs 86.3±35.6 µm; p<0.01) and lower central pachymetry measurements (442.1±56.7 vs 454.4±47.5 µm; p=0.01). Age at presentation, gender, atopy, documented eye rubbing, ethnicity and duration of follow-up were not significantly associated with progression in the multivariate analyses. There was a higher rate of bilateral progression if at least one eye had severe keratoconus (73.9%) compared with no severe keratoconus in either eye (36.8%; p=0.03)., Conclusions: A high rate of progression was identified in keratoconic eyes of children and adolescents. More advanced disease at initial presentation may increase the risk of further keratoconus progression., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.)
Published: 2023
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34. Rates of Herpes Simplex Virus Types 1 and 2 in Ocular and Peri-ocular Specimens.

Author: Meyer JJ
Subjects: Humans, Retrospective Studies, Eye, Herpesvirus 2, Human genetics, Herpesvirus 1, Human genetics, Keratitis, Herpetic diagnosis, Keratitis, Herpetic epidemiology, Herpes Simplex diagnosis, Herpes Simplex epidemiology
Abstract: Purpose: To evaluate the rates of Herpes Simplex Virus types 1 (HSV-1) and 2 (HSV-2) in ocular specimens., Methods: Retrospective case series of all patients with a positive laboratory evaluation for ocular HSV performed at the Auckland District Health Board, Auckland, New Zealand between 1 January 2006 and 31 December 2017 were included in the study., Results: A total of 423 specimens were positive for HSV-1 (99.3%, n = 419) or HSV-2 (0.7%; n = 4). The majority of positive tests were identified through DNA amplification (n = 352; 83%) testing while the remainder were obtained by viral culture (n = 71; 17%). Ocular disease caused by HSV-2 in this study included acute retinal necrosis (n = 2), keratitis (n = 1), and blepharitis (n = 1)., Conclusions: HSV type 2 is a rare cause of ocular and peri-ocular infection but may cause severe, vision threatening disease.
Published: 2023
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35. Neurotrophic Keratopathy After Herpes Zoster Ophthalmicus.

Author: Meyer JJ, Liu K, McGhee CNJ, Danesh-Meyer HV, and Niederer RL
Subjects: Aged, Female, Humans, Male, Retrospective Studies, Vision Disorders, Visual Acuity, Corneal Dystrophies, Hereditary complications, Herpes Zoster Ophthalmicus complications, Keratitis complications, Keratitis etiology, Trigeminal Nerve Diseases, Uveitis complications
Abstract: Purpose: The aim of this study was to describe risk factors for neurotrophic keratopathy (NK) after herpes zoster ophthalmicus (HZO)., Methods: This study was a retrospective review of all patients seen at the Auckland District Health Board with HZO from 2006 through 2016. Cox proportional hazards analysis was performed to examine time to development of neurotrophic keratitis., Results: Eight hundred sixty-nine patients were included in the study with a median follow-up of 6.3 years (5504.4 patient-years). The median age was 65.5 years (interquartile range 52.9-75.4), and 456 subjects (52.5%) were male. NK developed in 58 patients (6.7%), with the highest hazard 1 to 2 years after onset of HZO. On univariate analysis, age, White ethnicity, best-corrected visual acuity (BCVA) at presentation, intraocular pressure, corneal involvement, uveitis, and number of recurrences were associated with increased risk of NK. On multivariate analysis, the following factors were significant: age (hazard ratio [HR] = 1.03; P = 0.021), White ethnicity (HR = 3.18; P = 0.015), BCVA (HR = 1.81; P = 0.026), uveitis (HR = 3.77; P = 0.001), and recurrence (HR = 1.34; P < 0.001). Vision loss (BCVA ≤6/15) was more frequent in subjects with NK (65.5% vs. 16.3%, P < 0.001)., Conclusions: NK is a relatively common and serious complication of HZO and occurs more frequently in older White individuals, those with poor visual acuity at presentation, and those with uveitis. Vision loss occurs in approximately two-thirds of patients., Competing Interests: The authors have no funding or conflicts of interest to disclose., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
Published: 2022
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36. Prompt Antiviral Therapy Is Associated With Lower Risk of Cerebrovascular Accident Following Herpes Zoster Ophthalmicus.

Author: Meyer JJ, Liu K, Danesh-Meyer HV, and Niederer RL
Subjects: Acyclovir therapeutic use, Aged, Antiviral Agents therapeutic use, Female, Humans, Male, Retrospective Studies, Exanthema, Herpes Zoster Ophthalmicus complications, Herpes Zoster Ophthalmicus diagnosis, Herpes Zoster Ophthalmicus drug therapy, Stroke etiology
Abstract: Purpose: To examine risk factors associated with cerebrovascular accident (CVA) following herpes zoster ophthalmicus (HZO)., Design: Retrospective cohort study., Methods: Review of medical records of all patients with HZO seen at the department of Ophthalmology, Auckland District Health Board, New Zealand, between January 1, 2006, and December 31, 2016. The main outcome measure was cerebrovascular accident within 12 months of diagnosis., Results: A total of 869 patients diagnosed with HZO were included in the study. The median age at onset of HZO was 65.5 years (interquartile range [IQR] 52.9-75.4), and 52.5% (n=456) were male. Antiviral therapy was started in 765 participants (88.0%), not used in 95 (10.9%), and not documented in 9 participants (1.0%). Four hundred sixty-eight participants (54.9%) received prompt oral antiviral therapy (≤72 hours of rash onset). A CVA occurred in the 12 months following HZO in 14 patients (1.6%) and was most common in older patients, occurring in 2.5% aged ≥65 years, 0.7% aged 40-65 years, and 0.9% aged <40 years. Hazard of CVA was highest immediately following HZO, with median time to CVA of 2.3 months (IQR 0.8-5.9 months). Patients who received prompt acyclovir had a 76.2% lower hazard of CVA (0.9% vs 2.6%, P = .022) on multivariate analysis., Conclusions: Cerebrovascular accident occurs in a low proportion of individuals within 1 year following HZO. Antiviral treatment for HZO may reduce the risk of subsequent CVA when given within 72 hours of rash onset., (Copyright © 2022 Elsevier Inc. All rights reserved.)
Published: 2022
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37. Alterations in the ocular surface and tear film following keratoplasty.

Author: Meyer JJ, Gokul A, Wang MTM, Sung J, and Craig JP
Subjects: Cross-Sectional Studies, Fluoresceins, Humans, Keratoplasty, Penetrating adverse effects, Tears physiology, Corneal Transplantation adverse effects
Abstract: The purpose of this study was to evaluate any alterations in the tear film and ocular surface beyond the early postoperative period following penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK). This cross-sectional, contralateral-eye study compared ocular surface and tear film parameters of eyes with a previous PK or DALK in one eye and no prior surgery in the contralateral eye. Overall, 14 (87.5%) participants underwent PK, and 2 (12.5%) underwent DALK using a mechanical dissection. The median time from surgery was 3.4 years (range 1.5 to 38.7 years). The indication for unilateral keratoplasty was keratoconus in 15 (94%) participants, and corneal scarring in 1 (6%) eye, secondary to microbial keratitis. Operated eyes exhibited poorer non-invasive tear film breakup time, lower corneal sensitivity, lower sub-basal nerve density and more severe fluorescein staining scores than unoperated fellow eyes (all Q < 0.05). There were no significant differences in tear film lipid layer quality, tear meniscus height, conjunctival hyperaemia, lissamine green staining score, or meibography grade between operated and fellow eyes (all Q ≥ 0.20). Higher corneal esthesiometry threshold (lower corneal sensitivity) was correlated with shorter non-invasive tear film breakup time (Spearman's rho = - 0.361, p = 0.04) and increased fluorescein staining score (Spearman's rho = 0.417, p = 0.02). Keratoplasty can induce persistent changes in the ocular surface and tear film, including: increased fluorescein staining, decreased tear film breakup time, decreased corneal sub-basal nerve plexus density, and reduced corneal sensitivity., (© 2022. The Author(s).)
Published: 2022
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38. Reply : Cataract surgery in herpes simplex virus ocular disease.

Author: Lu LM, Al-Ani HH, Meyer JJ, and Niederer RL
Subjects: Eye, Humans, Simplexvirus, Cataract complications, Keratitis, Herpetic diagnosis, Keratitis, Herpetic drug therapy
Published: 2022
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39. Location, Location, Location: What Should be Targeted Beyond Gross Disease for Localized Pancreatic Ductal Adenocarcinoma? Proposal of a Standardized Clinical Tumor Volume for Pancreatic Ductal Adenocarcinoma of the Head: The "Triangle Volume".

Author: Hill CS, Fu W, Hu C, Sehgal S, Reddy AV, He J, Herman JM, Meyer JJ, Zaheer A, and Narang AK
Subjects: Humans, Neoadjuvant Therapy, Tumor Burden, Pancreatic Neoplasms, Adenocarcinoma pathology, Carcinoma, Pancreatic Ductal radiotherapy, Pancreatic Neoplasms pathology
Abstract: Purpose: In patients with borderline resectable or locally advanced pancreatic adenocarcinoma (BRPC/LAPC), local failure rates after resection remain significant, even in the setting of neoadjuvant chemotherapy and radiation. Suboptimal local control may relate to variable radiation target delineation, as no consensus exists around clinical tumor volume (CTV) design in this context. In the surgical literature, recent attention has been given to the "triangle" volume (TV) as a source of subclinical, residual disease. To understand whether the TV can inform optimal CTV design, we mapped locoregional failures after resection in a large cohort of patients with BRPC/LAPC and compared locations of failure to the TV., Methods and Materials: Patients with BRPC/LAPC of the head or neck diagnosed between 2016 AND 2019 who developed locoregional failure after surgery, neoadjuvant chemotherapy, and radiation were identified. Descriptive statistics were generated to report the frequency of locoregional failures located within the TV and the frequency of new vascular involvement at time of failure, compared with vascular involvement at diagnosis. Additionally, dosimetric coverage of the TV with the preoperative radiation plan that had been used was assessed., Results: In 31 patients who experienced locoregional failure, the centroid of failure was located within the TV in 28 cases (90%). Extent of vascular involvement at time of locoregional failure included vasculature that had not been involved at diagnosis in 13 cases (42%). The preoperative radiation plan that had been used provided a median V33 Gy and V25 Gy of the TV of only 53% (interquartile range, 34%-72%) and 70% (IQR, 48%-85%), respectively., Conclusions: The TV encompassed the vast majority of locoregional failures, but dosimetric coverage of the TV was poor when only targeting gross disease and the full circumference of involved vasculature. As such, the TV may better serve as a basis for CTV design in patients with BRPC/LAPC undergoing neoadjuvant radiation., (Copyright © 2022 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.)
Published: 2022
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40. Case Report: Acute Corneal Hydrops despite Accelerated Transepithelial Corneal Cross-linking.

Author: Meyer JJ and Gokul A
Subjects: Adult, Cornea, Corneal Topography, Cross-Linking Reagents therapeutic use, Edema, Female, Humans, Photosensitizing Agents, Riboflavin, Ultraviolet Rays, Visual Acuity, Young Adult, Corneal Edema diagnosis, Corneal Edema etiology, Keratoconus complications, Keratoconus diagnosis
Abstract: Significance: Corneal cross-linking is a well-established treatment to reduce or halt the progression of keratoconus. This case demonstrates that acute corneal hydrops may develop several years after corneal cross-linking even despite apparent treatment effect with corneal flattening, and patients should be monitored accordingly., Purpose: This study aimed to describe a case of continued progression in the form of corneal hydrops despite prior corneal cross-linking and evidence of treatment effect., Case Report: A 19-year-old woman underwent bilateral accelerated transepithelial corneal cross-linking for progressive keratoconus. At 2 years after the procedure, significant flattening of the central cornea of >3 D was measured in the left eye, indicating a significant treatment response, although continued thinning was noted on tomography. At 3.5 years after the procedure, this eye developed acute corneal hydrops with subsequent corneal scarring necessitating corneal transplantation., Conclusions: Patients should continue to be monitored for several years after corneal cross-linking, and retreatment should be considered if there is progressive corneal thinning., Competing Interests: Conflict of Interest Disclosure: No conflict of interest exists for any author., (Copyright © 2022 American Academy of Optometry.)
Published: 2022
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41. Cataract surgery in herpes simplex virus ocular disease.

Author: Al-Ani HH, Lu LM, Meyer JJ, and Niederer RL
Subjects: Humans, Postoperative Complications, Retrospective Studies, Simplexvirus, Visual Acuity, Cataract complications, Cataract Extraction
Abstract: Purpose: To investigate the outcomes and complications associated with cataract surgery in eyes with herpes simplex virus (HSV)-related anterior segment ocular disease., Setting: Public tertiary center in Auckland, New Zealand., Design: Retrospective observational cohort study., Methods: Clinical records of patients diagnosed with HSV-related keratitis and/or anterior uveitis who underwent subsequent cataract surgery in the affected eye were reviewed. Main outcomes measured were visual outcome, complications, and recurrence., Results: 37 eyes of 37 patients were included. Intraoperative complications occurred in 1 patient (2.7%) with iris prolapse. Keratitis or uveitis recurred postoperatively in 17 patients (45.9%) 8 patients (22.5%); 22.5% experienced recurrences in the first year postoperatively. 1 case (2.7%) of postoperative cystoid macular edema and 1 (2.7%) postoperative endophthalmitis occurred. Corrected distance visual acuity at 3 months was >20/50 in 21 patients (70.0%), 20/50 to 20/200 in 4 patients (12.9%), and ≤20/200 in 6 patients (19.4%). Vision improved in 26 eyes (83.9%) and worsened in only 1 eye (3.2%). Risk for recurrent inflammation was associated with a greater number of recurrences prior to surgery (hazard rate [HR] 1.31), time quiescent prior to surgery (HR 0.48), and iris transillumination defect at preoperative assessment (HR 57.66)., Conclusions: Cataract surgery in eyes with previous HSV disease may improve visual acuity for most of the eyes but, overall, carries a guarded prognosis, particularly in eyes with corneal scarring. There is a significant risk for recurrent inflammation in the first year postoperatively. If possible, surgeons should ensure a period of disease quiescence prior to surgery., (Copyright © 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.)
Published: 2022
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42. Iris Cyst

Author: Han LS and Meyer JJ
Abstract: Iris cysts are not common and can provide a challenge for clinicians in terms of diagnosis and management. Iris is the colored muscular diaphragm with a circular central aperture forming the pupil. It is uveal tissue composed of stroma anteriorly and two layers of pigment epithelial cells posteriorly. Primary cysts can arise from both the pigment epithelium and stroma. Secondary cysts may arise from the iris tissue or the implantation of other material. Knowledge of the condition and the method of evaluating iris cysts is important to making the correct diagnosis. There are controversies regarding the best management, and often treatments are advised in a step-wise fashion in terms of invasiveness. Treatment is sometimes indicated to prevent secondary complications., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

43. Bimatoprost Ophthalmic Solution

Author: Huang AS and Meyer JJ
Abstract: Bimatoprost ophthalmic solution is an eye drop medication used to lower intraocular pressure in patients with open-angle glaucoma and ocular hypertension and cosmetically to treat hypotrichosis. It is a prostaglandin F2 alpha analog. This activity covers the indications, mechanisms of action, administration, adverse effects, contraindications and highlights the role of education from an interprofessional team to optimize treatment with bimatoprost ophthalmic solution., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

44. Lens Induced Glaucoma

Author: Shah SS and Meyer JJ
Abstract: Lens-induced glaucoma (LIG) was originally described by Gifford in 1900 as glaucoma associated with hyper-mature senile cataracts (HMSC). Von Ruess independently described LIG as glaucoma with spontaneous absorption of lens matter through an intact capsule.[1] The literature has a multitude of similar entities described over the decades. LIG is secondary glaucoma mimicking acute angle-closure glaucoma (ACG), with normal intraocular pressure (IOP) and open-angles in the contralateral eye, and prompt relief of symptoms following cataract extraction. Based on the pathogenesis, LIG is further classified as: 1. Lens protein-related: Leakage of lens protein across an intact or a breached lens capsule. This form includes: Phacolytic glaucoma (PLG). Lens-particle induced glaucoma (LPIG). Phacoanaphylactic glaucoma (PAG). 2. Aqueous flow obstruction: Anatomical obstruction of aqueous flow from the posterior to the anterior chamber. This type includes: Phacomorphic glaucoma (PMG). Pupillary block glaucoma (PBG). Some causes like pseudo-exfoliation glaucoma and ciliary block glaucoma are debatable entities under LIG., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

45. Degenerative Myopia

Author: Yap A and Meyer JJ
Abstract: Myopia, colloquially referred to as shortsightedness or nearsightedness, is one of the most common global eye diseases. It occurs when the optical power of the eye is too high for the corresponding axial length of the eye, resulting in images of distant objects being focused in front of the retina. Myopia can be corrected by wearing glasses, contact lenses, or refractive surgery. However, pathologic myopia (PM) refers to a subset of ocular conditions associated with high myopia. The exact diagnostic criteria of PM have not been established. Some have defined PM based on an absolute cutoff value of refractive power (-6 to -8D) or axial length (26.5mm), while others have based it on the presence of myopic maculopathy.[1][2], (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

46. Dry Eye Syndrome

Author: Golden MI, Meyer JJ, and Patel BC
Abstract: Dry eyes, also known as dry eye disease (DED), dry eye syndrome, and keratoconjunctivitis sicca (KCS) are one of the most common reasons for a visit to an eye doctor. The definition of a dry eye according to the Tear Film and Ocular Surface Society Dry Eye Workshop II is: "Dry eye is a multifactorial disease of the ocular surface characterized by a loss of homeostasis of the tear film, and accompanied by ocular symptoms, in which tear film instability and hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities play etiologic roles." The tear film is approximately 2 to 5 µm thick over the cornea and is composed of three main components. These components (lipid, aqueous, and mucin) are often described as layers, although this may be an oversimplification of the tear film milieu. The most superficial layer, the lipid layer, is produced by the meibomian glands of the eyelids and functions to reduce the evaporation of tears. The middle aqueous layer is the thickest component of the tear film and is produced by the lacrimal glands, located in the orbits, and the accessory lacrimal glands (glands of Krause and Wolfring) in the conjunctiva. The basal layer is composed of mucins, or glycoproteins, and is predominantly produced by conjunctival goblet cells. Mucins enhance the spread of the tear film over the corneal epithelium through the regulation of surface tension., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

47. Chronic Closed Angle Glaucoma

Author: Dave SD and Meyer JJ
Abstract: Glaucoma is a heterogeneous condition that leads to damage of the optic nerve and may result in visual field loss, including complete blindness. Anatomically, glaucoma is classified into open-angle glaucoma and closed-angle glaucoma. A closed-angle is an anatomical configuration in which there is a mechanical blockage of the trabecular meshwork by the peripheral iris. Etiologically, it can be classified as primary or secondary angle closure. Primary angle closure is not associated with any other ocular condition, while secondary angle closure is associated with one or more other ocular conditions. Clinically, angle-closure can be considered acute or chronic. Chronic angle-closure can occur with or without symptoms, and thus it can be described as ''silent" closed-angle glaucoma. Because this condition mainly consists of irido-trabecular contact leading to synechiae formation and subsequent angle closure, it has also been described as "creeping" angle closure.[1], (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

48. Neovascular Glaucoma

Author: Mishra C and Meyer JJ
Abstract: Neovascular glaucoma (NVG) is a form of secondary glaucoma characterized by new vessels on the iris and angle of the anterior chamber (AC). It is usually associated with a poor visual prognosis.[1][2][3] The mechanism of anterior segment neovascularization is ischemia of the posterior segment of the eye resulting from a number of ophthalmic and systemic etiologies.[3][4]The most common etiologies include proliferative diabetic retinopathy (PDR), central retinal vein occlusion (CRVO), and ocular ischemic syndrome (OIS).[5] In 1906, Coats described new vessels over the iris (rubeosis iridis) in a patient with CRVO. Due to the formation of new vessels in the anterior segment of the eye, the rise in intraocular pressure, and the connective tissue growth, the term NVG was coined by Weiss et al.[6] Some other synonyms used for NVG are hemorrhagic glaucoma, thrombotic glaucoma, and congestive glaucoma.[2] NVG is usually refractory to treatments, and visual morbidity is significant for the patient. There are increasing numbers of NVG cases, probably due to the rise in the number of patients with diabetes and other non-communicable diseases, which are risk factors for retinovascular entities such as diabetic retinopathy, retinal vein occlusions, and ocular ischemic syndromes. Knowledge of the evaluation and management of NVG is crucial for all ophthalmologists., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

49. Normal Tension Glaucoma

Author: Gosling D and Meyer JJ
Abstract: Glaucoma is characteristic progressive optic neuropathy, featuring optic disc cupping and visual field loss, associated with raised intraocular pressure (IOP). Normal-tension glaucoma (NTG), also known as normal or low-pressure glaucoma, is defined as open-angle glaucoma with a presenting IOP in the normal range. The pathogenesis remains poorly understood, and there is controversy over whether it is a spectrum of primary open-angle glaucoma (POAG) or represents heterogeneous diseases. The impact of NTG can range from non-progressive, asymptomatic disease to bilateral blindness. An impaired visual field leading to loss of a driving license can have a major impact on quality of life. Adverse effects and costs of medical and surgical treatments should be weighed against the risk of visual loss. NTG can masquerade as other optic neuropathies, and care should be taken to adequately investigate other causes when indicated., (Copyright © 2022, StatPearls Publishing LLC.)
Published: 2022

50. Blood-Based Targeted Metabolomics Discriminate Patients with Alcoholic Liver Cirrhosis from Those with Non-Cirrhotic Liver Damage: An Explorative Study.

Author: Meyer JJ, Dreyhaupt J, Schwerdel D, Ettrich TJ, Backhus J, Dollinger MM, Seufferlein T, and Berger AW
Subjects: Humans, Liver Cirrhosis diagnosis, Liver Cirrhosis, Alcoholic diagnosis, Metabolomics methods, Carcinoma, Hepatocellular diagnosis, Liver Neoplasms diagnosis
Abstract: Background: Early detection of liver cirrhosis is crucial for secondary prevention of complications. However, noninvasive blood-based patient monitoring tools are lacking. In this explorative study, we conducted a targeted metabolomic analysis in order to identify possible serum markers indicating alcoholic liver cirrhosis (aLiC) with or without hepatocellular carcinoma (HCC)., Methods: Venous blood of 30 individuals was collected: healthy controls ("Con", n = 12), patients with aLiC without and with HCC ("aLiC": n = 6 and "aLiC + HCC": n = 6), and patients with other liver diseases ("oLiD": n = 6). A targeted metabolomic analysis was conducted using the AbsoluteIDQ® p180 Kit (Biocrates Life Sciences®, Innsbruck, Austria). Statistical analysis was performed by applying a one-way ANOVA on all subgroups followed by a t test for pairwise comparison of subgroups and logistic regression analysis., Results: ANOVA revealed 29 metabolites that significantly discriminate between the different cohorts. Among these analytes, 25 were significantly altered in Con versus aLiC, as indicated by t test, most importantly SM C18:1 (p < 0.001), SM C20:2 (p = 0.001), SM (OH) C22:2 (p < 0.001), lysoPC a C20:4 (p < 0.001), and PC aa C36:5 (p < 0.001). To a similar extent, the metabolites discriminated also between the oLiD and aLiC but less between the Con or oLiD and aLiC + HCC cohorts. Most of these analytes were either lyso- and phosphatidylcholines or sphingomyelins. Results were not significant for comparison of Con versus oLiD and aLiC versus aLiC + HCC., Conclusion: Decreased lyso- and phosphatidylcholine as well as sphingomyelin species in venous blood could help to detect liver cirrhosis in patients with non-cirrhotic liver disease., (© 2021 S. Karger AG, Basel.)
Published: 2022
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