270 results on '"Meyer, Michelle N."'
Search Results
2. Public views on polygenic screening of embryos
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Meyer, Michelle N, Tan, Tammy, Benjamin, Daniel J, Laibson, David, and Turley, Patrick
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Policy and Administration ,Human Society ,Multifactorial Inheritance ,Genetic Testing ,Risk ,Embryo ,Mammalian ,Humans ,Gene Editing ,Policy Making ,United States ,General Science & Technology - Abstract
Understanding moral acceptability and willingness to use is crucial for informing policy.
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- 2023
3. Enhancing the ethics of user-sourced online data collection and sharing
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Meyer, Michelle N., Basl, John, Choffnes, David, Wilson, Christo, and Lazer, David M. J.
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- 2023
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4. Against One-Size-Fits-All Research Ethics
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Meyer, Michelle N.
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- 2010
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5. Comparison of Clinical Decision Support Tools to Improve Pediatric Lipid Screening
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Goren, Amir, Santos, Henri C., Davis, Thomas W., Lowe, Robert B., Monfette, Mariya, Meyer, Michelle N., and Chabris, Christopher F.
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- 2024
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6. Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
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Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A, Ahlskog, Rafael, Magnusson, Patrik KE, Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J, Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D, Johannesson, Magnus, Laibson, David, Meyer, Michelle N, Lee, James J, Kong, Augustine, Yengo, Loic, Cesarini, David, Turley, Patrick, Visscher, Peter M, Beauchamp, Jonathan P, Benjamin, Daniel J, and Young, Alexander I
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Human Genome ,Genetics ,Pediatric ,Aetiology ,2.1 Biological and endogenous factors ,Genome-Wide Association Study ,Humans ,Multifactorial Inheritance ,Polymorphism ,Single Nucleotide ,23andMe Research Team ,Social Science Genetic Association Consortium ,Biological Sciences ,Medical and Health Sciences ,Developmental Biology - Abstract
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12-16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half the PGI's magnitude of association with EA and other phenotypes. The correlation between mate-pair PGIs is far too large to be consistent with phenotypic assortment alone, implying additional assortment on PGI-associated factors. In an additional GWAS of dominance deviations from the additive model, we identify no genome-wide-significant SNPs, and a separate X-chromosome additive GWAS identifies 57.
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- 2022
7. Resource profile and user guide of the Polygenic Index Repository
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Becker, Joel, Burik, Casper AP, Goldman, Grant, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Belsky, Daniel W, Karlsson Linnér, Richard, Ahlskog, Rafael, Kleinman, Aaron, Hinds, David A, Caspi, Avshalom, Corcoran, David L, Moffitt, Terrie E, Poulton, Richie, Sugden, Karen, Williams, Benjamin S, Harris, Kathleen Mullan, Steptoe, Andrew, Ajnakina, Olesya, Milani, Lili, Esko, Tõnu, Iacono, William G, McGue, Matt, Magnusson, Patrik KE, Mallard, Travis T, Harden, K Paige, Tucker-Drob, Elliot M, Herd, Pamela, Freese, Jeremy, Young, Alexander, Beauchamp, Jonathan P, Koellinger, Philipp D, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M, Meyer, Michelle N, Laibson, David, Cesarini, David, Benjamin, Daniel J, Turley, Patrick, and Okbay, Aysu
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Epidemiology ,Health Sciences ,2.6 Resources and infrastructure (aetiology) ,Aetiology ,Data Analysis ,Databases ,Genetic ,Genome-Wide Association Study ,Humans ,Multifactorial Inheritance ,Polymorphism ,Single Nucleotide ,Polygenic score ,Polygenic index ,Repository ,Measurement error ,23andMe Research Group ,Biomedical and clinical sciences ,Health sciences ,Psychology - Abstract
Polygenic indexes (PGIs) are DNA-based predictors. Their value for research in many scientific disciplines is growing rapidly. As a resource for researchers, we used a consistent methodology to construct PGIs for 47 phenotypes in 11 datasets. To maximize the PGIs' prediction accuracies, we constructed them using genome-wide association studies-some not previously published-from multiple data sources, including 23andMe and UK Biobank. We present a theoretical framework to help interpret analyses involving PGIs. A key insight is that a PGI can be understood as an unbiased but noisy measure of a latent variable we call the 'additive SNP factor'. Regressions in which the true regressor is this factor but the PGI is used as its proxy therefore suffer from errors-in-variables bias. We derive an estimator that corrects for the bias, illustrate the correction, and make a Python tool for implementing it publicly available.
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- 2021
8. Problems with Using Polygenic Scores to Select Embryos
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Turley, Patrick, Meyer, Michelle N, Wang, Nancy, Cesarini, David, Hammonds, Evelynn, Martin, Alicia R, Neale, Benjamin M, Rehm, Heidi L, Wilkins-Haug, Louise, Benjamin, Daniel J, Hyman, Steven, Laibson, David, and Visscher, Peter M
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Reproductive Medicine ,Biomedical and Clinical Sciences ,Aging ,Educational Status ,Embryo ,Mammalian ,Fertilization in Vitro ,Gene-Environment Interaction ,Genetic Testing ,Genetic Variation ,Genome-Wide Association Study ,Humans ,Multifactorial Inheritance ,Phenotype ,Predictive Value of Tests ,Preimplantation Diagnosis ,Medical and Health Sciences ,General & Internal Medicine ,Biomedical and clinical sciences ,Health sciences - Abstract
Companies have recently begun to sell a new service to patients considering in vitro fertilization: embryo selection based on polygenic scores (ESPS). These scores represent individualized predictions of health and other outcomes derived from genomewide association studies in adults to partially predict these outcomes. This article includes a discussion of many factors that lower the predictive power of polygenic scores in the context of embryo selection and quantifies these effects for a variety of clinical and nonclinical traits. Also discussed are potential unintended consequences of ESPS (including selecting for adverse traits, altering population demographics, exacerbating inequalities in society, and devaluing certain traits). Recommendations for the responsible communication about ESPS by practitioners are provided, and a call for a society-wide conversation about this technology is made. (Funded by the National Institute on Aging and others.).
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- 2021
9. A megastudy of text-based nudges encouraging patients to get vaccinated at an upcoming doctor’s appointment
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Milkman, Katherine L., Patel, Mitesh S., Gandhi, Linnea, Graci, Heather N., Gromet, Dena M., Ho, Hung, Kay, Joseph S., Lee, Timothy W., Akinola, Modupe, Beshears, John, Bogard, Jonathan E., Buttenheim, Alison, Chabris, Christopher F., Chapman, Gretchen B., Choi, James J., Dai, Hengchen, Fox, Craig R., Goren, Amir, Hilchey, Matthew D., Hmurovic, Jillian, John, Leslie K., Karlan, Dean, Kim, Melanie, Laibson, David, Lamberton, Cait, Madrian, Brigitte C., Meyer, Michelle N., Modanu, Maria, Nam, Jimin, Rogers, Todd, Rondina, Renante, Saccardo, Silvia, Shermohammed, Maheen, Soman, Dilip, Sparks, Jehan, Warren, Caleb, Weber, Megan, Berman, Ron, Evans, Chalanda N., Snider, Christopher K., Tsukayama, Eli, Van den Bulte, Christophe, Volpp, Kevin G., and Duckworth, Angela L.
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- 2021
10. Computational ethics
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Awad, Edmond, Levine, Sydney, Anderson, Michael, Anderson, Susan Leigh, Conitzer, Vincent, Crockett, M.J., Everett, Jim A.C., Evgeniou, Theodoros, Gopnik, Alison, Jamison, Julian C., Kim, Tae Wan, Liao, S. Matthew, Meyer, Michelle N., Mikhail, John, Opoku-Agyemang, Kweku, Borg, Jana Schaich, Schroeder, Juliana, Sinnott-Armstrong, Walter, Slavkovik, Marija, and Tenenbaum, Josh B.
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- 2022
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11. A single intranasal dose of human parainfluenza virus type 3-vectored vaccine induces effective antibody and memory T cell response in the lungs and protects hamsters against SARS-CoV-2
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Ilinykh, Philipp A., Periasamy, Sivakumar, Huang, Kai, Kuzmina, Natalia A., Ramanathan, Palaniappan, Meyer, Michelle N., Mire, Chad E., Kuzmin, Ivan V., Bharaj, Preeti, Endsley, Jessica R., Chikina, Maria, Sealfon, Stuart C., Widen, Steven G., Endsley, Mark A., and Bukreyev, Alexander
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- 2022
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12. Reports of the Death of Expertise may be Exaggerated
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Santos, Henri C., primary, Meyer, Michelle N., additional, and Chabris, Christopher F., additional
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- 2022
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13. Objecting to experiments even while approving of the policies or treatments they compare
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Heck, Patrick R., Chabris, Christopher F., Watts, Duncan J., and Meyer, Michelle N.
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- 2020
14. REPLY TO MISLAVSKY ET AL. : Sometimes people really are averse to experiments
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Meyer, Michelle N., Heck, Patrick R., Holtzman, Geoffrey S., Anderson, Stephen M., Cai, William, Watts, Duncan J., and Chabris, Christopher F.
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- 2019
15. Potential corporate uses of polygenic indexes: Starting a conversation about the associated ethics and policy issues.
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Meyer, Michelle N., Papageorge, Nicholas W., Parens, Erik, Regenberg, Alan, Sugarman, Jeremy, and Thom, Kevin
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ECOLOGY , *ETHICS , *CONSUMERS - Abstract
Some commercial firms currently sell polygenic indexes (PGIs) to individual consumers, despite their relatively low predictive power. It might be tempting to assume that because the predictive power of many PGIs is so modest, other sorts of firms—such as those selling insurance and financial services—will not be interested in using PGIs for their own purposes. We argue to the contrary. We build this argument in two ways. First, we offer a very simple model, rooted in economic theory, of a profit-maximizing firm that can gain information about a single consumer's genome. We use the model to show that, depending on the specific economic environment, a firm would be willing to pay for statistically noisy PGIs, even if they allow for only a small reduction in uncertainty. Second, we describe two plausible scenarios in which these different kinds of firms could conceivably use PGIs to maximize profits. Finally, we briefly discuss some of the associated ethics and policy issues. They deserve more attention, which is unlikely to be given until it is first recognized that firms whose services affect a large swath of the public will indeed have incentives to use PGIs. Despite the relative noisiness of polygenic indexes (PGIs), some commercial firms will use them. We offer a simple model, rooted in economic theory, to show how acquiring PGIs could be profitable and describe two scenarios where firms could use them. Finally, we discuss some associated ethics and policy issues. [ABSTRACT FROM AUTHOR]
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- 2024
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16. Ethics and Potential Opportunities and Risks of Corporate Uses of Socioeconomic Polygenic Risk Scores
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Meyer, Michelle N., primary, Papageorge, Nicholas W., additional, Parens, Erik, additional, Regenberg, Alan, additional, Sugarman, Jeremy, additional, and Thom, Kevin, additional
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- 2024
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17. Of Parachutes and Participant Protection : Moving Beyond Quality to Advance Effective Research Ethics Oversight
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Lynch, Holly Fernandez, Nicholls, Stuart, Meyer, Michelle N., and Taylor, Holly A.
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- 2019
18. Objecting to experiments that compare two unobjectionable policies or treatments
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Meyer, Michelle N., Heck, Patrick R., Holtzman, Geoffrey S., Anderson, Stephen M., Cai, William, Watts, Duncan J., and Chabris, Christopher F.
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- 2019
19. To respond or not to respond: The effect of forced and prefer not to answer options in demographic questionnaires
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Santos, Henri C., primary, Mestechkin, Rebecca M, additional, Vogt, Randi L., additional, Rosica, Daniel, additional, Heck, Patrick Ryan, additional, Heydari, Pedram, additional, Brown, Matt, additional, Rosenbaum, Gail, additional, Shermohammed, Maheen, additional, Meyer, Michelle N., additional, and Chabris, Christopher F., additional
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- 2023
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20. An illusion of predictability in scientific results: Even experts confuse inferential uncertainty and outcome variability
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Zhang, Sam, primary, Heck, Patrick R., additional, Meyer, Michelle N., additional, Chabris, Christopher F., additional, Goldstein, Daniel G., additional, and Hofman, Jake M., additional
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- 2023
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21. Correction to: Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants
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Buchanan, Adam H., Manickam, Kandamurugu, Meyer, Michelle N., Wagner, Jennifer K., Hallquist, Miranda L. G., Williams, Janet L., Rahm, Alanna Kulchak, Williams, Marc S., Chen, Zong-Ming E., Shah, Chaitali K., Garg, Tullika K., Lazzeri, Amanda L., Schwartz, Marci L. B., Lindbuchler, D’ Andra M., Fan, Audrey L., Leeming, Rosemary, Servano, III, Pedro O., Smith, Ashlee L., Vogel, Victor G., Abul-Husn, Noura S., Dewey, Frederick E., Lebo, Matthew S., Mason-Suares, Heather M., Ritchie, Marylyn D., Davis, F. Daniel, Carey, David J., Feinberg, David T., Faucett, W. Andrew, Ledbetter, David H., and Murray, Michael F.
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- 2021
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22. at law: Regulating Research with Biospecimens under the Revised Common Rule
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Lynch, Holly Fernandez and Meyer, Michelle N.
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- 2017
23. Pediatric reporting of genomic results study (PROGRESS): a mixed-methods, longitudinal, observational cohort study protocol to explore disclosure of actionable adult- and pediatric-onset genomic variants to minors and their parents
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Savatt, Juliann M., Wagner, Jennifer K., Joffe, Steven, Rahm, Alanna Kulchak, Williams, Marc S., Bradbury, Angela R., Davis, F. Daniel, Hergenrather, Julie, Hu, Yirui, Kelly, Melissa A., Kirchner, H. Lester, Meyer, Michelle N., Mozersky, Jessica, O’Dell, Sean M., Pervola, Josie, Seeley, Andrea, Sturm, Amy C., and Buchanan, Adam H.
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- 2020
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24. Pandemic Pandemonium: Pausing Clinical Research During the COVID-19 Outbreak
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Byrd, James Brian, Bello, Natalie, and Meyer, Michelle N.
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- 2020
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25. Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participants
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Buchanan, Adam H, Manickam, Kandamurugu, Meyer, Michelle N, Wagner, Jennifer K, Hallquist, Miranda L G, Williams, Janet L, Rahm, Alanna Kulchak, Williams, Marc S, Chen, Zong-Ming E, Shah, Chaitali K, Garg, Tullika K, Lazzeri, Amanda L, Schwartz, Marci L B, Lindbuchler, D'Andra M, Fan, Audrey L, Leeming, Rosemary, Servano, III, Pedro O, Smith, Ashlee L, Vogel, Victor G, Abul-Husn, Noura S, Dewey, Frederick E, Lebo, Matthew S, Mason-Suares, Heather M, Ritchie, Marylyn D, Davis, F Daniel, Carey, David J, Feinberg, David T, Faucett, W Andrew, Ledbetter, David H, and Murray, Michael F
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- 2018
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26. Experiment aversion among clinicians and the public — an obstacle to evidence-based medicine and public health
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Vogt, Randi L., primary, Heck, Patrick R., additional, Mestechkin, Rebecca M., additional, Heydari, Pedram, additional, Chabris, Christopher F., additional, and Meyer, Michelle N., additional
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- 2023
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27. Wrestling with Public Input on an Ethical Analysis of Scientific Research
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Martschenko, Daphne Oluwaseun, primary, Callier, Shawneequa L., additional, Garrison, Nanibaa’ A., additional, Lee, Sandra Soo‐Jin, additional, Turley, Patrick, additional, Meyer, Michelle N., additional, and Parens, Erik, additional
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- 2023
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28. Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility
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Meyer, Michelle N., primary, Appelbaum, Paul S., additional, Benjamin, Daniel J., additional, Callier, Shawneequa L., additional, Comfort, Nathaniel, additional, Conley, Dalton, additional, Freese, Jeremy, additional, Garrison, Nanibaa' A., additional, Hammonds, Evelynn M., additional, Harden, K. Paige, additional, Lee, Sandra Soo‐Jin, additional, Martin, Alicia R., additional, Martschenko, Daphne Oluwaseun, additional, Neale, Benjamin M., additional, Palmer, Rohan H. C., additional, Tabery, James, additional, Turkheimer, Eric, additional, Turley, Patrick, additional, and Parens, Erik, additional
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- 2023
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29. Computational ethics
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Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Awad, Edmond, Levine, Sydney, Anderson, Michael, Anderson, Susan Leigh, Conitzer, Vincent, Crockett, MJ, Everett, Jim AC, Evgeniou, Theodoros, Gopnik, Alison, Jamison, Julian C, Kim, Tae Wan, Liao, S Matthew, Meyer, Michelle N, Mikhail, John, Opoku-Agyemang, Kweku, Borg, Jana Schaich, Schroeder, Juliana, Sinnott-Armstrong, Walter, Slavkovik, Marija, Tenenbaum, Josh B, Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences, Awad, Edmond, Levine, Sydney, Anderson, Michael, Anderson, Susan Leigh, Conitzer, Vincent, Crockett, MJ, Everett, Jim AC, Evgeniou, Theodoros, Gopnik, Alison, Jamison, Julian C, Kim, Tae Wan, Liao, S Matthew, Meyer, Michelle N, Mikhail, John, Opoku-Agyemang, Kweku, Borg, Jana Schaich, Schroeder, Juliana, Sinnott-Armstrong, Walter, Slavkovik, Marija, and Tenenbaum, Josh B
- Abstract
Technological advances are enabling roles for machines that present novel ethical challenges. The study of 'AI ethics' has emerged to confront these challenges, and connects perspectives from philosophy, computer science, law, and economics. Less represented in these interdisciplinary efforts is the perspective of cognitive science. We propose a framework - computational ethics - that specifies how the ethical challenges of AI can be partially addressed by incorporating the study of human moral decision-making. The driver of this framework is a computational version of reflective equilibrium (RE), an approach that seeks coherence between considered judgments and governing principles. The framework has two goals: (i) to inform the engineering of ethical AI systems, and (ii) to characterize human moral judgment and decision-making in computational terms. Working jointly towards these two goals will create the opportunity to integrate diverse research questions, bring together multiple academic communities, uncover new interdisciplinary research topics, and shed light on centuries-old philosophical questions.
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- 2023
30. A Randomized Trial of Behavioral Nudges Delivered Through Text Messages to Increase Influenza Vaccination Among Patients With an Upcoming Primary Care Visit
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Patel, Mitesh S., primary, Milkman, Katherine L., additional, Gandhi, Linnea, additional, Graci, Heather N., additional, Gromet, Dena, additional, Ho, Hung, additional, Kay, Joseph S., additional, Lee, Timothy W., additional, Rothschild, Jake, additional, Akinola, Modupe, additional, Beshears, John, additional, Bogard, Jonathan E., additional, Buttenheim, Alison, additional, Chabris, Christopher, additional, Chapman, Gretchen B., additional, Choi, James J., additional, Dai, Hengchen, additional, Fox, Craig R., additional, Goren, Amir, additional, Hilchey, Matthew D., additional, Hmurovic, Jillian, additional, John, Leslie K., additional, Karlan, Dean, additional, Kim, Melanie, additional, Laibson, David, additional, Lamberton, Cait, additional, Madrian, Brigitte C., additional, Meyer, Michelle N., additional, Modanu, Maria, additional, Nam, Jimin, additional, Rogers, Todd, additional, Rondina, Renante, additional, Saccardo, Silvia, additional, Shermohammed, Maheen, additional, Soman, Dilip, additional, Sparks, Jehan, additional, Warren, Caleb, additional, Weber, Megan, additional, Berman, Ron, additional, Evans, Chalanda N., additional, Lee, Seung Hyeong, additional, Snider, Christopher K., additional, Tsukayama, Eli, additional, Van den Bulte, Christophe, additional, Volpp, Kevin G., additional, and Duckworth, Angela L., additional
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- 2022
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31. Genome-wide association study identifies 74 loci associated with educational attainment
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Okbay, Aysu, Beauchamp, Jonathan P., Fontana, Mark Alan, Lee, James J., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Pina Concas, Maria, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, Lee, Sven J. van der, deLeeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., van der Most, Peter J., Oldmeadow, Christopher, Payton, Antony, Pervjakova, Natalia, Peyrot, Wouter J., Qian, Yong, Raitakari, Olli, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., St Pourcain, Beate, Teumer, Alexander, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Westra, Harm-Jan, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eibich, Peter, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Joshi, Peter K., Jugessur, Astanand, Kaakinen, Marika A., Kähönen, Mika, Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Kutalik, Zoltan, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Cohort Study, LifeLines, Loukola, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Meddens, Gerardus A., McMahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Milani, Lili, Montgomery, Grant W., Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, van Rooij, Frank J. A., Venturini, Cristina, Vinkhuyzen, Anna A. E., Völker, Uwe, Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Boomsma, Dorret I., Borecki, Ingrid B., Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., van Duijn, Cornelia M., Eriksson, Johan G., Franke, Barbara, Franke, Lude, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, van der Harst, Pim, Hayward, Caroline, Hinds, David A., Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehtimäki, Terho, Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., McGue, Matt, Metspalu, Andres, Pendleton, Neil, Penninx, Brenda W. J. H., Perola, Markus, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Tung, Joyce Y., Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Davey Smith, George, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Yang, Jian, Johannesson, Magnus, Visscher, Peter M., Esko, Tõnu, Koellinger, Philipp D., Cesarini, David, and Benjamin, Daniel J.
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- 2016
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32. Prediction of Influenza Complications: Development and Validation of a Machine Learning Prediction Model to Improve and Expand the Identification of Vaccine-Hesitant Patients at Risk of Severe Influenza Complications
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Wolk, Donna M., primary, Lanyado, Alon, additional, Tice, Ann Marie, additional, Shermohammed, Maheen, additional, Kinar, Yaron, additional, Goren, Amir, additional, Chabris, Christopher F., additional, Meyer, Michelle N., additional, Shoshan, Avi, additional, and Abedi, Vida, additional
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- 2022
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33. Exploring access to genomic risk information and the contours of the HIPAA public health exception
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Wagner, Jennifer K, primary, Tanniru, Juhi K, additional, Chane, Courtney A, additional, and Meyer, Michelle N, additional
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- 2022
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34. GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
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The LifeLines Cohort Study, Rietveld, Cornelius A., Medland, Sarah E., Derringer, Jaime, Yang, Jian, Esko, Tõnu, Martin, Nicolas W., Westra, Harm-Jan, Shakhbazov, Konstantin, Abdellaoui, Abdel, Agrawal, Arpana, Albrecht, Eva, Alizadeh, Behrooz Z., Amin, Najaf, Barnard, John, Baumeister, Sebastian E., Benke, Kelly S., Bielak, Lawrence F., Boatman, Jeffrey A., Boyle, Patricia A., Davies, Gail, de Leeuw, Christiaan, Eklund, Niina, Evans, Daniel S., Ferhmann, Rudolf, Fischer, Krista, Gieger, Christian, Gjessing, Håkon K., Hägg, Sara, Harris, Jennifer R., Hayward, Caroline, Holzapfel, Christina, Ibrahim-Verbaas, Carla A., Ingelsson, Erik, Jacobsson, Bo, Joshi, Peter K., Jugessur, Astanand, Kaakinen, Marika, Kanoni, Stavroula, Karjalainen, Juha, Kolcic, Ivana, Kristiansson, Kati, Kutalik, Zoltán, Lahti, Jari, Lee, Sang H., Lin, Peng, Lind, Penelope A., Liu, Yongmei, Lohman, Kurt, Loitfelder, Marisa, McMahon, George, Vidal, Pedro Marques, Meirelles, Osorio, Milani, Lili, Myhre, Ronny, Nuotio, Marja-Liisa, Oldmeadow, Christopher J., Petrovic, Katja E., Peyrot, Wouter J., Polašek, Ozren, Quaye, Lydia, Reinmaa, Eva, Rice, John P., Rizzi, Thais S., Schmidt, Helena, Schmidt, Reinhold, Smith, Albert V., Smith, Jennifer A., Tanaka, Toshiko, Terracciano, Antonio, van der Loos, Matthijs J. H. M., Vitart, Veronique, Völzke, Henry, Wellmann, Jürgen, Yu, Lei, Zhao, Wei, Allik, Jüri, Attia, John R., Bandinelli, Stefania, Bastardot, François, Beauchamp, Jonathan, Bennett, David A., Berger, Klaus, Bierut, Laura J., Boomsma, Dorret I., Bültmann, Ute, Campbell, Harry, Chabris, Christopher F., Cherkas, Lynn, Chung, Mina K., Cueca, Francesco, de Andrade, Mariza, De Jager, Philip L., De Neve, Jan-Emmanuel, Deary, Ian J., Dedoussis, George V., Deloukas, Panos, Dimitriou, Maria, Eiríksdóttir, Guðný, Elderson, Martin F., Eriksson, Johan G., Evans, David M., Faul, Jessica D., Ferrucci, Luigi, Garcia, Melissa E., Grönberg, Henrik, Guðnason, Vilmundur, Hall, Per, Harris, Juliette M., Harris, Tamara B., Hastie, Nicholas D., Heath, Andrew C., Hernandez, Dena G., Hoffmann, Wolfgang, Hofman, Adriaan, Holle, Rolf, Holliday, Elizabeth G., Hottenga, Jouke-Jan, Iacono, William G., Illig, Thomas, Järvelin, Marjo-Riitta, Kähönen, Mika, Kaprio, Jaakko, Kirkpatrick, Robert M., Kowgier, Matthew, Latvala, Antti, Launer, Lenore J., Lawior, Debbie A., Lehtimäki, Terho, Li, Jingmei, Lichtenstein, Paul, Lichtner, Peter, Liewald, David C., Madden, Pamela A., Magnusson, Patrik K. E., Mäkinen, Tomi E., Masala, Marco, McGue, Matt, Metspalu, Andres, Mielck, Andreas, Miller, Michael B., Montgomery, Grant W., Mukherjee, Sutapa, Nyholt, Dale R., Oostra, Ben A., Palmer, Lyle J., Palotie, Aarno, Penninx, Brenda W. J. H., Perola, Markus, Peyser, Patricia A., Preisig, Martin, Räikkönen, Katri, Raitakari, Olli T., Realo, Anu, Ring, Susan M., Ripatti, Samuli, Rivadeneira, Fernando, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sarin, Antti-Pekka, Schlessinger, David, Scott, Rodney J., Snieder, Harold, St Pourcain, Beate, Starr, John M., Sul, Jae Hoon, Surakka, Ida, Svento, Rauli, Teumer, Alexander, Tiemeier, Henning, van Rooij, Frank J. A., Van Wagoner, David R., Vartiainen, Erkki, Viikari, Jorma, Vollenweider, Peter, Vonk, Judith M., Waeber, Gérard, Weir, David R., Wichmann, H.-Erich, Widen, Elisabeth, Willemsen, Gonneke, Wilson, James F., Wright, Alan F., Conley, Dalton, Davey-Smith, George, Franke, Lude, Groenen, Patrick J. F., Hofman, Albert, Johannesson, Magnus, Kardia, Sharon L. R., Krueger, Robert F., Laibson, David, Martin, Nicholas G., Meyer, Michelle N., Posthuma, Danielle, Thurik, A. Roy, Timpson, Nicholas J., Uitterlinden, André G., van Duijn, Cornelia M., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David, and Koellinger, Philipp D.
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- 2013
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35. REGULATING THE PRODUCTION OF KNOWLEDGE: RESEARCH RISK–BENEFIT ANALYSIS AND THE HETEROGENEITY PROBLEM
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Meyer, Michelle N.
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- 2013
36. policy and politics: From Evidence-Based Medicine to Evidence-Based Practice
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Meyer, Michelle N.
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- 2013
37. Computational ethics
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Edmond, Awad, Levine, Sydney, Anderson, Michael, Susan Leigh, Anderson, Conitzer, Vincent, Crockett, M.J., Everett, Jim A.C., Evgeniou, Theodoros, Gopnik, Alison, Jamison, Julian C., Kim, Taw Wan, Liao, S. Matthew, Meyer, Michelle N., Mikhail, John, Opoku-Agyemang, Kweku, Schaich Borg, Jana, Schroeder, Juliana, Sinott-Armstrong, Walter, Slavkovik, Marija, and Tenenbaum, Josh B.
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Judgment ,Philosophy ,Engineering ,Neuropsychology and Physiological Psychology ,ComputingMilieux_THECOMPUTINGPROFESSION ,Cognitive Neuroscience ,Decision Making ,Humans ,Experimental and Cognitive Psychology ,Morals - Abstract
Technological advances are enabling roles for machines that present novel ethical challenges. The study of 'AI ethics' has emerged to confront these challenges, and connects perspectives from philosophy, computer science, law, and economics. Less represented in these interdisciplinary efforts is the perspective of cognitive science. We propose a framework – computational ethics – that specifies how the ethical challenges of AI can be partially addressed by incorporating the study of human moral decision-making. The driver of this framework is a computational version of reflective equilibrium (RE), an approach that seeks coherence between considered judgments and governing principles. The framework has two goals: (i) to inform the engineering of ethical AI systems, and (ii) to characterize human moral judgment and decision-making in computational terms. Working jointly towards these two goals will create the opportunity to integrate diverse research questions, bring together multiple academic communities, uncover new interdisciplinary research topics, and shed light on centuries-old philosophical questions. publishedVersion
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- 2022
38. An illusion of predictability in scientific results
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Zhang, Sam, primary, Heck, Patrick Ryan, additional, Meyer, Michelle N., additional, Chabris, Christopher F., additional, Goldstein, Daniel G, additional, and Hofman, Jake M., additional
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- 2022
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39. A 680,000-person megastudy of nudges to encourage vaccination in pharmacies
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Milkman, Katherine L., primary, Gandhi, Linnea, additional, Patel, Mitesh S., additional, Graci, Heather N., additional, Gromet, Dena M., additional, Ho, Hung, additional, Kay, Joseph S., additional, Lee, Timothy W., additional, Rothschild, Jake, additional, Bogard, Jonathan E., additional, Brody, Ilana, additional, Chabris, Christopher F., additional, Chang, Edward, additional, Chapman, Gretchen B., additional, Dannals, Jennifer E., additional, Goldstein, Noah J., additional, Goren, Amir, additional, Hershfield, Hal, additional, Hirsch, Alex, additional, Hmurovic, Jillian, additional, Horn, Samantha, additional, Karlan, Dean S., additional, Kristal, Ariella S., additional, Lamberton, Cait, additional, Meyer, Michelle N., additional, Oakes, Allison H., additional, Schweitzer, Maurice E., additional, Shermohammed, Maheen, additional, Talloen, Joachim, additional, Warren, Caleb, additional, Whillans, Ashley, additional, Yadav, Kuldeep N., additional, Zlatev, Julian J., additional, Berman, Ron, additional, Evans, Chalanda N., additional, Ladhania, Rahul, additional, Ludwig, Jens, additional, Mazar, Nina, additional, Mullainathan, Sendhil, additional, Snider, Christopher K., additional, Spiess, Jann, additional, Tsukayama, Eli, additional, Ungar, Lyle, additional, Van den Bulte, Christophe, additional, Volpp, Kevin G., additional, and Duckworth, Angela L., additional
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- 2022
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40. Supplemental material - A Randomized Trial of Behavioral Nudges Delivered Through Text Messages to Increase Influenza Vaccination Among Patients With an Upcoming Primary Care Visit
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Patel, Mitesh S., Milkman, Katherine L., Gandhi, Linnea, Graci, Heather N., Gromet, Dena, Ho, Hung, Kay, Joseph S., Lee, Timothy W., Rothschild, Jake, Akinola, Modupe, Beshears, John, Bogard, Jonathan E., Buttenheim, Alison, Chabris, Christopher, Chapman, Gretchen B., Choi, James J., Dai, Hengchen, Fox, Craig R., Goren, Amir, Hilchey, Matthew D., Hmurovic, Jillian, John, Leslie K., Karlan, Dean, Kim, Melanie, Laibson, David, Lamberton, Cait, Madrian, Brigitte C., Meyer, Michelle N., Modanu, Maria, Nam, Jimin, Rogers, Todd, Rondina, Renante, Saccardo, Silvia, Shermohammed, Maheen, Soman, Dilip, Sparks, Jehan, Warren, Caleb, Weber, Megan, Berman, Ron, Evans, Chalanda N., Lee, Seung Hyeong, Snider, Christopher K., Tsukayama, Eli, Van den Bulte, Christophe, Volpp, Kevin G., and Duckworth, Angela L.
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111799 Public Health and Health Services not elsewhere classified ,FOS: Health sciences - Abstract
Supplemental material for A Randomized Trial of Behavioral Nudges Delivered Through Text Messages to Increase Influenza Vaccination Among Patients With an Upcoming Primary Care Visit by Mitesh Patel, Katherine L. Milkman, Linnea Gandhi, Heather N. Graci, Dena Gromet, Hung Ho, Joseph S. Kay, Timothy W. Lee, Jake Rothschild, Modupe Akinola, John Beshears, Jonathan E. Bogard, Alison Buttenheim, Christopher Chabris, Gretchen B. Chapman, James J. Choi, Hengchen Dai, Craig R. Fox, Amir Goren, Matthew D. Hilchey, Jillian Hmurovic, Leslie K. John, Dean Karlan, Melanie Kim, David Laibson, Cait Lamberton, Brigitte C. Madrian, Michelle N. Meyer, Maria Modanu, Jimin Nam, Todd Rogers, Renante Rondina, Silvia Saccardo, Maheen Shermohammed, Dilip Soman, Jehan Sparks, Caleb Warren, Megan Weber, Ron Berman, Chalanda N. Evans, Seung Hyeong Lee, Christopher K. Snider, Eli Tsukayama, Christophe Van den Bulte, Kevin G. Volpp, and Angela L. Duckworth in American Journal of Health Promotion
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- 2022
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41. policy and politics: Against One-Size-Fits-All Research Ethics
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Meyer, Michelle N.
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- 2010
42. Experiment aversion does generalize, but it can also be mitigated.
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Vogt, Randi L., Heck, Patrick R., Watts, Duncan J., Chabris, Christopher F., and Meyer, Michelle N.
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AVERSION ,COVID-19 pandemic ,INDIVIDUAL retirement accounts ,EMPLOYEE recruitment ,INFORMED consent (Medical law) - Abstract
The article explores the concept of experiment aversion (EA) and its applicability in different situations. The authors argue that EA can be influenced by various factors and can be reduced through interventions that address biases. They criticize a previous study that denied the existence of EA, pointing out flaws in its methodology and failure to consider certain factors. The authors emphasize the significance of consent and the impact of perceived knowledge on EA. They conclude that while EA can vary across contexts and societies, it is a phenomenon that can be alleviated. The text suggests that researchers should focus on understanding the circumstances and causes of EA, as well as finding ways to mitigate it, rather than attempting to disprove its existence. [Extracted from the article]
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- 2024
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43. Reports of the Death of Expertise May Be Exaggerated: Limits on Knowledge Resistance in Health and Medicine
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Santos, Henri C., primary, Meyer, Michelle N., additional, and Chabris, Christopher F., additional
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- 2021
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44. Allocation of Opportunities to Participate in Clinical Trials during the Covid‐19 Pandemic and Other Public Health Emergencies
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Spector‐Bagdady, Kayte, primary, Lynch, Holly Fernandez, additional, Bierer, Barbara E., additional, Gelinas, Luke, additional, Hull, Sara Chandros, additional, Magnus, David, additional, Meyer, Michelle N., additional, Sharp, Richard R., additional, Sugarman, Jeremy, additional, Wilfond, Benjamin S., additional, Yearby, Ruqaiijah, additional, and Mohapatra, Seema, additional
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- 2021
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45. Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
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Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Yang, Wu, Zhang, Futao, Agee, Michelle, Alipanahi, Babak, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Furlotte, Nicholas A., Huber, Karen E., Litterman, Nadia K., Mccreight, Jennifer C., Mcintyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Vacic, Vladimir, Wilson, Catherine H., Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Awadalla, Philip, Battle, Alexis, Beutner, Frank, Jan Bonder, Marc, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan, Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette, Kasela, Silva, Kettunen, Johannes, Kim, Yungil, Kirsten, Holger, Kovacs, Peter, Krohn, Knut, Kronberg-Guzman, Jaanika, Kukushkina, Viktorija, Kutalik, Zoltan, Lee, Bernett, Lehtimäki, Terho, Loeffler, Markus, Marigorta, Urko M., Metspalu, Andres, Milani, Lili, Montgomery, Grant W., Müller-Nurasyid, Martina, Nauck, Matthias, Penninx, Brenda, Perola, Markus, Pervjakova, Natalia, Pierce, Brandon, Powell, Joseph, Prokisch, Holger, Psaty, Bruce M., Raitakari, Olli, Ring, Susan, Ripatti, Samuli, Rotzchke, Olaf, Rüeger, Sina, Saha, Ashis, Scholz, Markus, Schramm, Katharina, Seppälä, Ilkka, Stumvoll, Michael, Sullivan, Patrick, Hoen, Peter-Bram t, Teumer, Alexander, Thiery, Joachim, Tong, Lin, Tönjes, Anke, Dongen, Jenny van, Meurs, Joyce van, Verlouw, Joost, Visscher, Peter M., Völker, Uwe, Võsa, Urmo, Westra, Harm-Jan, Yaghootkar, Hanieh, Yang, Jian, Zeng, Biao, Beauchamp, Jonathan P., Lee, James J., Pers, Tune H., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, Lee, Sven J. van der, de Leeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., Most, Peter J. van der, Oldmeadow, Christopher, Payton, Antony, Peyrot, Wouter J., Qian, Yong, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., Pourcain, Beate St, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klaus, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Panos, Demuth, Ilja, Ding, Jun, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Jugessur, Astanand, Kaakinen, Marika A., Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Mcmahon, George, Meisinger, Christa, Meitinger, Thomas, Milaneschi, Yusplitri, Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, Venturini, Cristina, Vinkhuyzen, Anna A. E., Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johannes, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klaus, Bertram, Lars, Bisgaard, Hans, Borecki, Ingrid B, Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., Duijn, Cornelia M. van, Eriksson, Johan G., Franke, Barbara, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, Harst, Pim van der, Hayward, Caroline, Hinds, David A., Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., Mcgue, Matt, Pendleton, Neil, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Johannesson, Magnus, Koellinger, Philipp D., Cesarini, David, Benjamin, Daniel J., Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Urs, Harris, Kathleen Mullan, Hasler, Gregor, Ikram, Mohammad A., Jain, Sonia, Kessler, Ronald C., Kooyman, Maarten, Mackillop, James, Männikkö, Minna, Morcillo-Suarez, Carlos, Mcqueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthias, White, Jon, Wit, Harriet de, Fehr, Ernst, Kumari, Meena, Laibson, David, Navarro, Arcadi, Palmer, Abraham A., Schunk, Daniel, Stein, Murray B., Svento, Rauli, Timmers, Paul R. H. J., Ursano, Robert J., Wagner, Gert G., Adult Psychiatry, APH - Mental Health, Psychiatry, Amsterdam Neuroscience - Complex Trait Genetics, Human genetics, Amsterdam Reproduction & Development (AR&D), APH - Digital Health, 23and Me Research Team, eQTLgen Consortium, International Cannabis Consortium, Economics, Biological Psychology, Complex Trait Genetics, APH - Methodology, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, APH - Health Behaviors & Chronic Diseases, APH - Personalized Medicine, Tinbergen Institute, 23andme Research Team, Psychiatric Genomics Consortium, Social Science Genetic Association Consortium, Linner Richard Karlsson, Biroli P, Kong Edward, Meddens Fleur W., Wedow Robbee, Fontana Mark Alan, Lebreton Mael, Tino Stephen P., Abdellaoui Abdel, Hammerschlag Anke R., Nivard Michel G., Okbay Aysu, Rietveld Cornelius A., Timshel Pascal N., Trzaskowski Maciej, de Vlaming Ronald, Zund Christian L., Bao Yanchun, Buzdugan Laura, Caplin Ann H., Chen Chia-Yen, Eibich Peter, Fontanillas Pierre, Gonzalez Juan R., Joshi Peter K., Karhunen Ville, Kleinman Aaron, Levin Remy Z., Lill Christina M., Meddens Gerardus A., Muntane Gerard, Sanchez-Roige Sandra, van Rooij Frank J., Taskesen Erdogan, Wu Yang, Zhang Futao, Agee Michelle, Alipanahi Babak, Bell Robert K., Bryc Katarzyna, Elson Sarah L., Furlotte Nicholas A., Huber Karen E., Litterman Nadia K., McCreight Jennifer C., McIntyre Matthew H., Mountain Joanna L., Northover Carrie A. M., Pitts Steven J., Sathirapongsasuti J. Fah, Sazonova Olga V., Shelton Janie F., Shringarpure Suyash, Tian Chao, Tung Joyce Y., Vacic Vladimir, Wilson Catherine H., Agbessi Mawusse, Ahsan Habibul, Alves Isabel, Andiappan Anand, Awadalla Philip, Battle Alexi, Beutner Frank, Bonder Marc Jan, Boomsma Dorret I., Christiansen Mark, Claringbould Annique, Deelen Patrick, Esko Tonu, Fave Marie-Julie, Franke Lude, Frayling Timothy, Gharib Sina A., Gibson Gregory, Heijmans Bastiaan, Hemani Gibran, Jansen Rick, Kahonen Mika, Kalnapenkis Anette, Kasela Silva, Kettunen Johanne, Kim Yungil, Kirsten Holger, Kovacs Peter, Krohn Knut, Kronberg-Guzman Jaanika, Kukushkina Viktorija, Kutalik Zoltan, Lee Bernett, Lehtimaki Terho, Loeffler Marku, Marigorta Urko M., Metspalu Andre, Milani Lili, Montgomery Grant W., Mueller-Nurasyid Martina, Nauck Matthia, Penninx Brenda, Perola Marku, Pervjakova Natalia, Pierce Brandon, Powell Joseph, Prokisch Holger, Psaty Bruce M., Raitakari Olli, Ring Susan, Ripatti Samuli, Rotzchke Olaf, Rueger Sina, Saha Ashi, Scholz Marku, Schramm Katharina, Seppala Ilkka, Stumvoll Michael, Sullivan Patrick, Hoen Peter-Bramt, Teumer Alexander, Thiery Joachim, Tong Lin, Tonjes Anke, van Dongen Jenny, van Meurs Joyce, Verlouw Joost, Visscher Peter M., Voelker Uwe, Vosa Urmo, Westra Harm-Jan, Yaghootkar Hanieh, Yang Jian, Zeng Biao, Lee James J., Pers Tune H., Turley Patrick, Chen Guo-Bo, Emilsson Valur, Oskarsson Sven, Pickrell Joseph K., Thom Kevin, Timshel Pascal, Ahluwalia Tarunveer S., Bacelis Jona, Baumbach Clemen, Bjornsdottir Gyda, Brandsma Johannes H., Concas Maria Pina, Derringer Jaime, Galesloot Tessel E., Girotto Giorgia, Gupta Richa, Hall Leanne M., Harris Sarah E., Hofer Edith, Horikoshi Momoko, Huffman Jennifer E., Kaasik Kadri, Kalafati Ioanna P., Kong Augustine, Lahti Jari, van der Lee Sven J., de Leeuw Christiaan, Lind Penelope A., Lindgren Karl-Oskar, Liu Tian, Mangino Massimo, Marten Jonathan, Mihailov Evelin, Miller Michael B., van der Most Peter J., Oldmeadow Christopher, Payton Antony, Peyrot Wouter J., Qian Yong, Rueedi Rico, Salvi Erika, Schmidt Boerge, Schraut Katharina E., Shi Jianxin, Smith Albert V., Poot Raymond A., St Pourcain Beate, Thorleifsson Gudmar, Verweij Niek, Vuckovic Dragana, Wellmann Juergen, Yang Jingyun, Zhao Wei, Zhu Zhihong, Alizadeh Behrooz Z., Amin Najaf, Bakshi Andrew, Baumeister Sebastian E., Biino Ginevra, Bonnelykke Klau, Boyle Patricia A., Campbell Harry, Cappuccio Francesco P., Davies Gail, De Neve Jan-Emmanuel, Deloukas Pano, Demuth Ilja, Ding Jun, Eisele Lewin, Eklund Niina, Evans David M., Faul Jessica D., Feitosa Mary F., Forstner Andreas J., Gandin Ilaria, Gunnarsson Bjarni, Halldorsson Bjarni V., Harris Tamara B., Heath Andrew C., Hocking Lynne J., Holliday Elizabeth G., Homuth Georg, Horan Michael A., Hottenga Jouke-Jan, de Jager Philip L., Jugessur Astanand, Kaakinen Marika A., Kanoni Stavroula, Keltigangas-Jarvinen Liisa, Kiemeney Lambertus A. L. M., Kolcic Ivana, Koskinen Seppo, Kraja Aldi T., Kroh Martin, Latvala Antti, Launer Lenore J., Lebreton Mael P., Levinson Douglas F., Lichtenstein Paul, Lichtner Peter, Liewald David C. M., Loukola Anu, Madden Pamela A., Magi Reedik, Maki-Opas Tomi, Marioni Riccardo E., Marques-Vidal Pedro, McMahon George, Meisinger Christa, Meitinger Thoma, Milaneschi Yusplitri, Myhre Ronny, Nelson Christopher P., Nyholt Dale R., Ollier William E. R., Palotie Aarno, Paternoster Lavinia, Pedersen Nancy L., Petrovic Katja E., Porteous David J., Raikkonen Katri, Ring Susan M., Robino Antonietta, Rostapshova Olga, Rudan Igor, Rustichini Aldo, Salomaa Veikko, Sanders Alan R., Sarin Antti-Pekka, Schmidt Helena, Scott Rodney J., Smith Blair H., Smith Jennifer A., Staessen Jan A., Steinhagen-Thiessen Elisabeth, Strauch Konstantin, Terracciano Antonio, Tobin Martin D., Ulivi Sheila, Vaccargiu Simona, Quaye Lydia, Venturini Cristina, Vinkhuyzen Anna A. E., Voelzke Henry, Vonk Judith M., Vozzi Diego, Waage Johanne, Ware Erin B., Willemsen Gonneke, Attia John R., Bennett David A., Berger Klau, Bertram Lar, Bisgaard Han, Borecki Ingrid B., Bultmann Ute, Chabris Christopher F., Cucca Francesco, Cusi Daniele, Deary J., Dedoussis George V., van Duijn Cornelia M., Eriksson Johan G., Franke Barbara, Gasparini Paolo, Gejman Pablo V., Gieger Christian, Grabe Hans-Joergen, Gratten Jacob, Gudnason Vilmundur, van der Harst Pim, Hayward Caroline, Hinds David A., Hoffmann Wolfgang, Hypponen Elina, Iacono William G., Jacobsson Bo, Jarvelin Marjo-Riitta, Jockel Karl-Heinz, Kaprio Jaakko, Kardia Sharon L. R., Lehrer Steven F., Magnusson Patrik K. E., Martin Nicholas G., McGue Matt, Pendleton Neil, Pirastu Nicola, Pirastu Mario, Polasek Ozren, Posthuma Danielle, Power Christine, Province Michael A., Samani Nilesh J., Schlessinger David, Schmidt Reinhold, Sorensen Thorkild I. A., Spector Tim D., Stefansson Kari, Thorsteinsdottir Unnur, Thurik A. Roy, Timpson Nicholas J., Tiemeier Henning, Uitterlinden Andre G., Vitart Veronique, Vollenweider Peter, Weir David R., Wilson James F., Wright Alan F., Conley Dalton C., Krueger Robert F., Smith George Davey, Laibson David I., Medland Sarah E., Johannesson Magnu, Koellinger Philipp D., Cesarini David, Benjamin Daniel J., Auton Adam, Boardman Jason D., Clark David W., Conlin Andrew, Dolan Conor C., Fischbacher Ur, Groenen Patrick J. F., Harris Kathleen Mullan, Hasler Gregor, Hofman Albert, Ikram Mohammad A., Jain Sonia, Karlsson Robert, Kessler Ronald C., Kooyman Maarten, MacKillop Jame, Mannikko Minna, Morcillo-Suarez Carlo, McQueen Matthew B., Schmidt Klaus M., Smart Melissa C., Sutter Matthia, White Jon, de Wit Harriet, Fehr Ernst, Kumari Meena, Laibson David, Meyer Michelle N., Navarro Arcadi, Palmer Abraham A., Schunk Daniel, Stein Murray B., Svento Rauli, Timmers Paul R. H. J., Ursano Robert J., Wagner Gert G., Beauchamp Jonathan P., Karlsson Linnér, Richard, Biroli, Pietro, Kong, Edward, Meddens, S. Fleur W., Wedow, Robbee, Fontana, Mark Alan, Lebreton, Maël, Tino, Stephen P., Abdellaoui, Abdel, Hammerschlag, Anke R., Nivard, Michel G., Okbay, Aysu, Rietveld, Cornelius A., Timshel, Pascal N., Trzaskowski, Maciej, Vlaming, Ronald de, Zünd, Christian L., Bao, Yanchun, Buzdugan, Laura, Caplin, Ann H., Chen, Chia-Yen, Eibich, Peter, Fontanillas, Pierre, Gonzalez, Juan R., Joshi, Peter K., Karhunen, Ville, Kleinman, Aaron, Levin, Remy Z., Lill, Christina M., Meddens, Gerardus A., Muntané, Gerard, Sanchez-Roige, Sandra, Rooij, Frank J. van, Taskesen, Erdogan, Wu, Yang, Zhang, Futao, Agee, Michelle, Alipanahi, Babak, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Furlotte, Nicholas A., Huber, Karen E., Litterman, Nadia K., Mccreight, Jennifer C., Mcintyre, Matthew H., Mountain, Joanna L., Northover, Carrie A. M., Pitts, Steven J., Sathirapongsasuti, J. Fah, Sazonova, Olga V., Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Vacic, Vladimir, Wilson, Catherine H., Agbessi, Mawussé, Ahsan, Habibul, Alves, Isabel, Andiappan, Anand, Awadalla, Philip, Battle, Alexi, Beutner, Frank, Jan Bonder, Marc, Boomsma, Dorret I., Christiansen, Mark, Claringbould, Annique, Deelen, Patrick, Esko, Tõnu, Favé, Marie-Julie, Franke, Lude, Frayling, Timothy, Gharib, Sina A., Gibson, Gregory, Heijmans, Bastiaan, Hemani, Gibran, Jansen, Rick, Kähönen, Mika, Kalnapenkis, Anette, Kasela, Silva, Kettunen, Johanne, Kim, Yungil, Kirsten, Holger, Kovacs, Peter, Krohn, Knut, Kronberg-Guzman, Jaanika, Kukushkina, Viktorija, Kutalik, Zoltan, Lee, Bernett, Lehtimäki, Terho, Loeffler, Marku, Marigorta, Urko M., Metspalu, Andre, Milani, Lili, Montgomery, Grant W., Müller-Nurasyid, Martina, Nauck, Matthia, Penninx, Brenda, Perola, Marku, Pervjakova, Natalia, Pierce, Brandon, Powell, Joseph, Prokisch, Holger, Psaty, Bruce M., Raitakari, Olli, Ring, Susan, Ripatti, Samuli, Rotzchke, Olaf, Rüeger, Sina, Saha, Ashi, Scholz, Marku, Schramm, Katharina, Seppälä, Ilkka, Stumvoll, Michael, Sullivan, Patrick, Hoen, Peter-Bram t, Teumer, Alexander, Thiery, Joachim, Tong, Lin, Tönjes, Anke, Dongen, Jenny van, Meurs, Joyce van, Verlouw, Joost, Visscher, Peter M., Völker, Uwe, Võsa, Urmo, Westra, Harm-Jan, Yaghootkar, Hanieh, Yang, Jian, Zeng, Biao, Beauchamp, Jonathan P., Lee, James J., Pers, Tune H., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Ahluwalia, Tarunveer S., Bacelis, Jona, Baumbach, Clemen, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E., Hofer, Edith, Horikoshi, Momoko, Huffman, Jennifer E., Kaasik, Kadri, Kalafati, Ioanna P., Karlsson, Robert, Kong, Augustine, Lahti, Jari, Lee, Sven J. van der, de Leeuw, Christiaan, Lind, Penelope A., Lindgren, Karl-Oskar, Liu, Tian, Mangino, Massimo, Marten, Jonathan, Mihailov, Evelin, Miller, Michael B., Most, Peter J. van der, Oldmeadow, Christopher, Payton, Antony, Peyrot, Wouter J., Qian, Yong, Rueedi, Rico, Salvi, Erika, Schmidt, Börge, Schraut, Katharina E., Shi, Jianxin, Smith, Albert V., Poot, Raymond A., Pourcain, Beate St, Thorleifsson, Gudmar, Verweij, Niek, Vuckovic, Dragana, Wellmann, Juergen, Yang, Jingyun, Zhao, Wei, Zhu, Zhihong, Alizadeh, Behrooz Z., Amin, Najaf, Bakshi, Andrew, Baumeister, Sebastian E., Biino, Ginevra, Bønnelykke, Klau, Boyle, Patricia A., Campbell, Harry, Cappuccio, Francesco P., Davies, Gail, De Neve, Jan-Emmanuel, Deloukas, Pano, Demuth, Ilja, Ding, Jun, Eisele, Lewin, Eklund, Niina, Evans, David M., Faul, Jessica D., Feitosa, Mary F., Forstner, Andreas J., Gandin, Ilaria, Gunnarsson, Bjarni, Halldórsson, Bjarni V., Harris, Tamara B., Heath, Andrew C., Hocking, Lynne J., Holliday, Elizabeth G., Homuth, Georg, Horan, Michael A., Hottenga, Jouke-Jan, de Jager, Philip L., Jugessur, Astanand, Kaakinen, Marika A., Kanoni, Stavroula, Keltigangas-Järvinen, Liisa, Kiemeney, Lambertus A. L. M., Kolcic, Ivana, Koskinen, Seppo, Kraja, Aldi T., Kroh, Martin, Latvala, Antti, Launer, Lenore J., Lebreton, Maël P., Levinson, Douglas F., Lichtenstein, Paul, Lichtner, Peter, Liewald, David C. M., Loukola, Anu, Madden, Pamela A., Mägi, Reedik, Mäki-Opas, Tomi, Marioni, Riccardo E., Marques-Vidal, Pedro, Mcmahon, George, Meisinger, Christa, Meitinger, Thoma, Milaneschi, Yusplitri, Myhre, Ronny, Nelson, Christopher P., Nyholt, Dale R., Ollier, William E. R., Palotie, Aarno, Paternoster, Lavinia, Pedersen, Nancy L., Petrovic, Katja E., Porteous, David J., Räikkönen, Katri, Ring, Susan M., Robino, Antonietta, Rostapshova, Olga, Rudan, Igor, Rustichini, Aldo, Salomaa, Veikko, Sanders, Alan R., Sarin, Antti-Pekka, Schmidt, Helena, Scott, Rodney J., Smith, Blair H., Smith, Jennifer A., Staessen, Jan A., Steinhagen-Thiessen, Elisabeth, Strauch, Konstantin, Terracciano, Antonio, Tobin, Martin D., Ulivi, Sheila, Vaccargiu, Simona, Quaye, Lydia, Venturini, Cristina, Vinkhuyzen, Anna A. E., Völzke, Henry, Vonk, Judith M., Vozzi, Diego, Waage, Johanne, Ware, Erin B., Willemsen, Gonneke, Attia, John R., Bennett, David A., Berger, Klau, Bertram, Lar, Bisgaard, Han, Borecki, Ingrid B, Bültmann, Ute, Chabris, Christopher F., Cucca, Francesco, Cusi, Daniele, Deary, Ian J., Dedoussis, George V., Duijn, Cornelia M. van, Eriksson, Johan G., Franke, Barbara, Gasparini, Paolo, Gejman, Pablo V., Gieger, Christian, Grabe, Hans-Jörgen, Gratten, Jacob, Groenen, Patrick J. F., Gudnason, Vilmundur, Harst, Pim van der, Hayward, Caroline, Hinds, David A., Hoffmann, Wolfgang, Hyppönen, Elina, Iacono, William G., Jacobsson, Bo, Järvelin, Marjo-Riitta, Jöckel, Karl-Heinz, Kaprio, Jaakko, Kardia, Sharon L. R., Lehrer, Steven F., Magnusson, Patrik K. E., Martin, Nicholas G., Mcgue, Matt, Pendleton, Neil, Pirastu, Nicola, Pirastu, Mario, Polasek, Ozren, Posthuma, Danielle, Power, Christine, Province, Michael A., Samani, Nilesh J., Schlessinger, David, Schmidt, Reinhold, Sørensen, Thorkild I. A., Spector, Tim D., Stefansson, Kari, Thorsteinsdottir, Unnur, Thurik, A. Roy, Timpson, Nicholas J., Tiemeier, Henning, Uitterlinden, André G., Vitart, Veronique, Vollenweider, Peter, Weir, David R., Wilson, James F., Wright, Alan F., Conley, Dalton C., Krueger, Robert F., Smith, George Davey, Hofman, Albert, Laibson, David I., Medland, Sarah E., Meyer, Michelle N., Johannesson, Magnu, Koellinger, Philipp D., Cesarini, David, Benjamin, Daniel J., Auton, Adam, Boardman, Jason D., Clark, David W., Conlin, Andrew, Dolan, Conor C., Fischbacher, Ur, Harris, Kathleen Mullan, Hasler, Gregor, Ikram, Mohammad A., Jain, Sonia, Kessler, Ronald C., Kooyman, Maarten, Mackillop, Jame, Männikkö, Minna, Morcillo-Suarez, Carlo, Mcqueen, Matthew B., Schmidt, Klaus M., Smart, Melissa C., Sutter, Matthia, White, Jon, Wit, Harriet de, Fehr, Ernst, Kumari, Meena, Laibson, David, Navarro, Arcadi, Palmer, Abraham A., Schunk, Daniel, Stein, Murray B., Svento, Rauli, Timmers, Paul R. H. J., Ursano, Robert J., Wagner, Gert G., Applied Economics, Hematology, Epidemiology, Urology, Department of Marketing Management, Internal Medicine, Medical Informatics, Cell biology, Erasmus MC other, Molecular Genetics, Econometrics, Child and Adolescent Psychiatry / Psychology, Radiology & Nuclear Medicine, Epidemiologie, RS: CARIM - R3.02 - Hypertension and target organ damage, RS: Carim - V02 Hypertension and target organ damage, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Groningen Research Institute for Asthma and COPD (GRIAC), Public Health Research (PHR), Cardiovascular Centre (CVC), Life Course Epidemiology (LCE), Stem Cell Aging Leukemia and Lymphoma (SALL), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Linnér, Richard Karlsson, Biroli , Pietro, Meddens, S Fleur W, and Beauchamp, Jonathan P
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Netherlands Twin Register (NTR) ,Male ,LD ,Medizin ,Poison control ,Genome-wide association study ,DETERMINANTS ,Cathie Marsh Institute ,PREFERENCES ,Q1 ,Genome-wide association studies ,HV ,0302 clinical medicine ,Genetics, Behavioral/methods ,GWAS ,Genetics & Heredity ,Genetics ,0303 health sciences ,PERSONALITY ,Genetic Predisposition to Disease/genetics ,Behavior/physiology ,Polymorphism, Single Nucleotide/genetics ,3. Good health ,Manchester Institute for Collaborative Research on Ageing ,Meta-analysis ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,Genetic Loci/genetics ,Behavioural genetics ,Genome-Wide Association Study/methods ,Medical genetics ,Female ,Life Sciences & Biomedicine ,Single Nucleotide/genetics ,medicine.medical_specialty ,ResearchInstitutes_Networks_Beacons/MICRA ,Genotype ,Single-nucleotide polymorphism ,Genetics, Behavioral ,Biology ,Polymorphism, Single Nucleotide ,Article ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,SDG 3 - Good Health and Well-being ,ddc:330 ,medicine ,GENDER-DIFFERENCES ,SNP ,Humans ,Genetic Predisposition to Disease ,Polymorphism ,behavioural genetics ,Behavioral/methods ,030304 developmental biology ,Genetic association ,Behavior ,Science & Technology ,Neurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7] ,Data Science ,Case-control study ,risk tolerance, GWAS, genetic architechture ,Genetic Loci ,Case-Control Studies ,genome-wide association studies ,ResearchInstitutes_Networks_Beacons/cathie_marsh_institute ,Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19] ,030217 neurology & neurosurgery ,Genome-Wide Association Study - Abstract
Humans vary substantially in their willingness to take risks. In a combined sample of over 1 million individuals, we conducted genome-wide association studies (GWAS) of general risk tolerance, adventurousness, and risky behaviors in the driving, drinking, smoking, and sexual domains. Across all GWAS, we identified hundreds of associated loci, including 99 loci associated with general risk tolerance. We report evidence of substantial shared genetic influences across risk tolerance and the risky behaviors: 46 of the 99 general risk tolerance loci contain a lead SNP for at least one of our other GWAS, and general risk tolerance is genetically correlated ([Formula: see text] ~ 0.25 to 0.50) with a range of risky behaviors. Bioinformatics analyses imply that genes near SNPs associated with general risk tolerance are highly expressed in brain tissues and point to a role for glutamatergic and GABAergic neurotransmission. We found no evidence of enrichment for genes previously hypothesized to relate to risk tolerance. This research was carried out under the auspices of the Social Science Genetic Association Consortium. The research was also conducted using the UK Biobank Resource under application number 11425. The study was supported by funding from the Ragnar Söderberg Foundation (E9/11 and E42/15); the Swedish Research Council (421-2013-1061); the Jan Wallander and Tom Hedelius Foundation; an ERC Consolidator Grant to Philipp Koellinger (647648 EdGe); the Pershing Square Fund of the Foundations of Human Behavior; the Open Philanthropy Project; the National Institute on Aging, National Institutes of Health through grants P01-AG005842, P01-AG005842-20S2, P30-AG012810, and T32-AG000186-23 to the National Bureau of Economic Research and R01-AG042568-02 to the University of Southern California; the government of Canada through Genome Canada and the Ontario Genomics Institute (OGI-152); and the Social Sciences and Humanities Research Council of Canada. We thank the International Cannabis Consortium, the eQTLgen Consortium, and the Psychiatric Genomics Consortium for sharing summary statistics from the GWAS of lifetime cannabis use, eQTL summary statistics, and summary statistics from the GWAS of ADHD, respectively. A full list of acknowledgments is provided in the Supplementary Note.
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- 2019
46. Effect of Targeted Behavioral Science Messages on COVID-19 Vaccination Registration Among Employees of a Large Health System
- Author
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Santos, Henri C., Goren, Amir, Chabris, Christopher F., and Meyer, Michelle N.
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Adult ,Male ,COVID-19 Vaccines ,Electronic Mail ,Immunization Programs ,Research ,Health Personnel ,Vaccination ,Online Only ,Infectious Diseases ,Research Letter ,Humans ,Female ,Behavioral Sciences - Abstract
This randomized trial evaluates whether individually addressed emails designed with behaviorally informed features increase COVID-19 vaccination rates.
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- 2021
47. Problems With Using Polygenic Scores to Select Embryos
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Turley, Patrick, primary, Meyer, Michelle N., additional, Wang, Nancy, additional, Cesarini, David, additional, Hammonds, Evelynn, additional, Martin, Alicia R., additional, Neale, Benjamin M., additional, Rehm, Heidi L., additional, Wilkins-Haug, Louise, additional, Benjamin, Daniel J., additional, Hyman, Steven, additional, Laibson, David, additional, and Visscher, Peter M., additional
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- 2021
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48. A Randomized Trial of Behavioral Nudges Delivered Through Text Messages to Increase Influenza Vaccination Among Patients With an Upcoming Primary Care Visit
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Patel, Mitesh S., Milkman, Katherine L., Gandhi, Linnea, Graci, Heather N., Gromet, Dena, Ho, Hung, Kay, Joseph S., Lee, Timothy W., Rothschild, Jake, Akinola, Modupe, Beshears, John, Bogard, Jonathan E., Buttenheim, Alison, Chabris, Christopher, Chapman, Gretchen B., Choi, James J., Dai, Hengchen, Fox, Craig R., Goren, Amir, Hilchey, Matthew D., Hmurovic, Jillian, John, Leslie K., Karlan, Dean, Kim, Melanie, Laibson, David, Lamberton, Cait, Madrian, Brigitte C., Meyer, Michelle N., Modanu, Maria, Nam, Jimin, Rogers, Todd, Rondina, Renante, Saccardo, Silvia, Shermohammed, Maheen, Soman, Dilip, Sparks, Jehan, Warren, Caleb, Weber, Megan, Berman, Ron, Evans, Chalanda N., Lee, Seung Hyeong, Snider, Christopher K., Tsukayama, Eli, Van den Bulte, Christophe, Volpp, Kevin G., and Duckworth, Angela L.
- Abstract
Purpose To evaluate if nudges delivered by text message prior to an upcoming primary care visit can increase influenza vaccination rates.Design Randomized, controlled trial.Setting Two health systems in the Northeastern US between September 2020 and March 2021.Subjects 74,811 adults.Interventions Patients in the 19 intervention arms received 1-2 text messages in the 3 days preceding their appointment that varied in their format, interactivity, and content.Measures Influenza vaccination.Analysis Intention-to-treat.Results Participants had a mean (SD) age of 50.7 (16.2) years; 55.8% (41,771) were female, 70.6% (52,826) were White, and 19.0% (14,222) were Black. Among the interventions, 5 of 19 (26.3%) had a significantly greater vaccination rate than control. On average, the 19 interventions increased vaccination relative to control by 1.8 percentage points or 6.1% (P= .005). The top performing text message described the vaccine to the patient as “reserved for you” and led to a 3.1 percentage point increase (95% CI, 1.3 to 4.9; P< .001) in vaccination relative to control. Three of the top five performing messages described the vaccine as “reserved for you.” None of the interventions performed worse than control.Conclusions Text messages encouraging vaccination and delivered prior to an upcoming appointment significantly increased influenza vaccination rates and could be a scalable approach to increase vaccination more broadly.
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- 2023
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49. Three Challenges for Risk-Based (Research) Regulation: Heterogeneity among Regulated Activities, Regulator Bias, and Stakeholder Heterogeneity
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Meyer, Michelle N., primary
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- 2014
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50. Consequences of rush to emergency use authorization of bamlanivimab
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Lussier, Mia, primary, Meyer, Michelle N, additional, and Wright, Eric, additional
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- 2021
- Full Text
- View/download PDF
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