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Your search keyword '"Mette Schødt"' showing total 2 results
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2 results on '"Mette Schødt"'

1. Pembrolizumab as first line treatment of Merkel cell carcinoma patients – a case series of patients with various co-morbidities

Author

Mette Schødt, Anders Krarup-Hansen, Niels Junker, Helle W. Hendel, and Tessa Bystrup Boyles

Subjects
Male, Oncology, medicine.medical_specialty, Skin Neoplasms, Comorbidity, Pembrolizumab, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Immunological, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, Aged, 80 and over, Series (stratigraphy), integumentary system, business.industry, Merkel cell carcinoma, Mortality rate, Advanced stage, food and beverages, Hematology, General Medicine, medicine.disease, Carcinoma, Merkel Cell, First line treatment, Female, Co morbidity, Skin cancer, business
Abstract

Merkel cell carcinoma (MCC) is a rare but highly aggressive neuroendocrine skin cancer associated with a high mortality rate in advanced stages [1,2]. For patients with non-resectable advanced/meta...

Published
2020
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2. Increased perirenal fat area is not associated with adverse outcomes after laparoscopic total mesorectal excision for rectal cancer

Author

Mette Schødt, Katarina Levic, Orhan Bulut, and Thue Bisgaard

Subjects
Adult, Male, medicine.medical_specialty, Colorectal cancer, Blood Loss, Surgical, Intra-Abdominal Fat, Kidney, Adipose capsule of kidney, Body Mass Index, 03 medical and health sciences, 0302 clinical medicine, Postoperative Complications, medicine, Humans, Adiposity, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Rectal Neoplasms, Perioperative, Vascular surgery, Middle Aged, medicine.disease, Total mesorectal excision, Surgery, Cardiac surgery, Cardiothoracic surgery, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, Female, Laparoscopy, business, Abdominal surgery
Abstract

Intraabdominal visceral obesity may increase technical challenges during laparoscopic rectal resection and hypothetically therefore increase the risk of perioperative complications. The aim of this study was to analyze intraabdominal obesity by means of perirenal fat against risk of adverse outcomes in patients undergoing laparoscopic rectal cancer surgery. This study was a single-institution retrospective analysis of consecutive patients undergoing laparoscopic total mesorectal surgery for rectal cancer between January 2009 and January 2013. Abdominal CT scans with intravenous contrast were assessed in a blinded manner to estimate the perirenal fat area (cm2). A total of 195 patients were included (median age 70 years (range 27–87), 58 women and 137 men) for analysis. There was a moderate correlation between BMI and perirenal fat area (r = 0.499, p = 0.001). Perirenal fat area was not associated with any of the measured adverse outcomes. Patients with BMI ≥ 30 had significantly higher intraoperative blood loss (191 mL, p = 0.001). Perirenal fat area was not an important predictor of adverse outcomes in patients undergoing laparoscopic rectal cancer surgery.

Published
2017

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