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1. Rappresentazione sociale della malattia mentale: una breve review sul ruolo dei mass media

Author

Martina Messina, Teresa Capparelli, Carmen Giannetti, Sara Scia, Claudia Langella

Subjects
rappresentazione sociale, malattia mentale, mass media, Pathology, RB1-214, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
Abstract

Questo lavoro analizza la letteratura esistente sul tema della rappresentazione sociale della malattia mentale, con una particolare attenzione all’impatto dei mass media. Obiettivo di questa review è indagare come le informazioni diffuse dai Mass Media influenzino l'opinione pubblica nella costruzione degli stereotipi sociali e come orientino le rappresentazioni sociali collettive, nella fattispecie della rappresentazione della malattia mentale. L’articolo passa in rassegna gli studi di diversi autori, a partire dalla scelta della terminologia utilizzata dai mass media. L’analisi include, inoltre, un focus sui programmi televisivi e i contenuti rivolti ai bambini.

Published
2022
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3. Sex Related Differences and Factors Associated With Peri-Procedural and One Year Mortality in Chronic Limb Threatening Ischaemia Patients

Author

Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Puci, Mariangela Valentina, Martelli, Allegra Rosa, Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Calia di Pinto, Luca, Fiore, Franco Michelino, Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massaro, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto Marcello, Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni Maria, Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaò, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio Stefano, D'Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D'Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gianfranco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio Massimo, and Settembrini, Alberto Maria

Published
2024
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4. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe M., additional, Puci, Mariangela V., additional, Martelli, Allegra R., additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco M., additional, Palmieri, Armando, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Piero, additional, Maiorano, Maurizio, additional, Bracale, Umberto M., additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni M., additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio S., additional, D’Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D’Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio M., additional, and Settembrini, Alberto M., additional

Published
2023
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5. Sex-Related Differences and Factors Associated with Peri-Procedural and 1-year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe Massimo, additional, Puci, Mariangela Valentina, additional, Martelli, Allegra Rosa, additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco Michelino, additional, Palmieri, Armado, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Pietro, additional, Maiorano, Maurizio, additional, Bracale, Umberto Marcello, additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni Maria, additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio Stefano, additional, D'Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D'Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio Massimo, additional, and Settembrini, Alberto Maria, additional

Published
2022
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7. Cardiac involvement in consecutive unselected hospitalized COVID-19 population: in-hospital evaluation and one-year follow-up

Author

Bruno Katia, Nicola Galea, Barletta Giovanna, Maldarelli Federica, De Lauri Daniela, Pasqualitto Fabiola, Prosperi Silvia, Francesco Pugliese, Titi Luca, Lucia Ilaria Birtolo, Del Bianco Andrea, Albante Alida, Francesco Fedele, Cappannoli Alessandro, Imperiale Carmela, Giannetti Lorena, Gabriella d'Ettorre, Marco Francone, Messina Teresa, Claudio Maria Mastroianni, Perrella Serena, Consolo Stella, De Rose Maria, Petroianni Angelo, Magnanimi Eugenia, Romano Hilde, Celli Paola, De Lazzaro Francesco, Carlo Catalano, Giulia d'Amati, Tosi Antonella, Brisciani Matteo, Martelli Sabina, Di Bella Valerio, Maestrini Ilaria, Paolo Severino, Massimo Mancone, Alberto Deales, Piazzolla Mario, Bilotta Federico, Bucarelli Maria Clelia, Maria Chiara Colaiacomo, Ricci Claudia, Croce Claudia, Tellan Guglielmo, Gioacchino Galardo, Ceccarelli Giancarlo, Ianni Stefano, Cristina Chimenti, Novelli Martina, Pasculli Patrizia, Verduci Noemi, Tordiglione Paolo, Santopietro Pietro, Rachele Edoardo Sebastian, Araimo Morselli Fabio, Auricchio Daniela, Manganelli Chiara, Letizia D'Antoni, Ratini Fabiola, Paolo Palange, Portieri Monica, Viviana Maestrini, Giordano Giovanni, Francavilla Santi, Maria Rosa Ciardi, Di Sano Laura, Pecorari Filippo, Carlo Lavalle, Di Santo Carmela, Crocitti Beatrice, Vaccaro Paola, Franco Ruberto, Trigilia Fausto, D'Antoni Letizia, Pattelli Elisa, Consoli Giulia, Francesco Alessandri, Sabani Anna, and Giulia Cundari

Subjects
medicine.medical_specialty, education.field_of_study, COPD, business.industry, medicine.medical_treatment, Population, Percutaneous coronary intervention, 030204 cardiovascular system & hematology, medicine.disease, COVID-19, cardiovascular disease, cardiovascular magnetic resonance, echocardiography, follow-up, myocarditis, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Heart failure, medicine, Medical history, cardiovascular diseases, 030212 general & internal medicine, Myocardial infarction, Cardiology and Cardiovascular Medicine, education, Prospective cohort study, business
Abstract

Background Cardiovascular disease (CVD) can occur in COVID-19 and has impact on clinical course. Data on CVD prevalence in hospitalized COVID-19 patients and sequelae in survivors is limited. Aim of this prospective study carried out on consecutive unselected COVID-19 population, was to assess: 1) CVD occurrence among hospitalized COVID-19 patients, 2) persistence or new onset of CVD at one-month and one-year follow-up. Methods Over 30 days n = 152 COVID-19 patients underwent cardiovascular evaluation. Standard electrocardiogram (ECG), Troponin and echocardiography were integrated by further tests when indicated. Medical history, arterial blood gas, blood tests, chest computed tomography and treatment were recorded. CVD was defined as the occurrence of a new condition during the hospitalization for COVID-19. Survivors attended a one-month follow-up visit and a one-year telephone follow-up. Results Forty-two patients (28%) experienced a wide spectrum of CVD with acute myocarditis being the most frequent. Death occurred in 32 patients (21%) and more frequently in patients who developed CVD (p = 0.032). After adjustment for confounders, CVD was independently associated with death occurrence. At one-month follow-up visit, 7 patients (9%) presented persistent or delayed CVD. At one-year telephone follow-up, 57 patients (48%) reported persistent symptoms. Conclusion Cardiovascular evaluation in COVID-19 patients is crucial since the occurrence of CVD in hospitalized COVID-19 patients is common (28%), requires specific treatment and increases the risk of in-hospital mortality. Persistence or delayed presentation of CVD at 1-month (9%) and persistent symptoms at 1-year follow-up (48%) suggest the need for monitoring COVID-19 survivors.

Published
2021

8. Usefulness of bronchoalveolar lavage in suspect COVID-19 repeatedly negative swab test and interstitial lung disease

Author

Albante, Alida, Alessandri, Francesco, Amore, Davide, Anile, Marco, Antognoli, Maria Gloria, Morselli, Fabio Araimo, Auricchio, Daniela, Bianco, Martina, Bilotta, Federico, Birtolo, Lucia Ilaria, Brisciani, Matteo, Bruno, Katia, Bufi, Maurizio, Cagnetti, Sara, Calzecchi, Elena, Cappannoli, Alessandro, Carillo, Carolina, Casaretti, Romina, Catalano, Carlo, Celli, Paola, Consolo, Stella, Croce, Claudia, Crocitti, Beatrice, Cuscianna, Enrica, D’Agostino, Federica Gilda, Giacomo, Tiziano De, Lauri, Daniela De, Lazzaro, Francesco De, Del Monte, Maurizio, D’Ettorre, Gabriella, Di Bella, Valerio, Fedele, Francesco, Gentile, Massimo, Giordano, Giovanni, Ianni, Stefano, Imperiale, Carmela, Infusino, Fabio, Loiacono, Cinzia, Maestrini, Viviana, Magnanimi, Eugenia, Maldarelli, Federica, Mantovani, Sara, Martelli, Sabina, Messercola, Paolo, Messina, Teresa, Mottola, Emilia, Pati, Valeria, Pattelli, Elisa, Pecorari, Filippo, Pecoraro, Ylenia, Perrella, Serena Maria, Piazzolla, Mario, Pietropaolo, Valeria, Poggi, Camilla, Portieri, Monica, Ratini, Fabiola, Ricci, Claudia, Ricci, Paolo, Rumori, Mario, Russo, Gianluca, Santopietro, Pietro, Tellan, Guglielmo, Titi, Luca, Tordiglione, Paolo, Tosi, Antonella, Tosti, Silvia, Trigilia, Fausto, Turriziani, Ombretta, Vaccaro, Paola, Verduci, Noemi, Vivino, Gabriella, Vannucci, Jacopo, Ruberto, Franco, Diso, Daniele, Galardo, Gioacchino, Mastroianni, Claudio M., Raponi, Giammarco, Bassi, Massimiliano, Ceccarelli, Giancarlo, Mancone, Massimo, Antonelli, Guido, Venuta, Federico, and Pugliese, Francesco

Published
2020
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10. Effect of low or high doses of low‐molecular‐weight heparin on thrombin generation and other haemostasis parameters in critically ill patients with COVID‐19

Author

Chistolini, Antonio, Ruberto, Franco, Alessandri, Francesco, Santoro, Cristina, Barone, Francesco, Cristina Puzzolo, Maria, Ceccarelli, Giancarlo, De Luca, Maria L., Mancone, Massimo, Alvaro, Domenico, Pulcinelli, Fabio M., Martelli, Maurizio, Foà, Robin, Pugliese, Francesco, Albante, Alida, Antonelli, Guido, Araimo‐Morselli, Fabio, Auricchio, Daniela, Baldacci, Erminia, Bilotta, Federico, Brisciani, Matteo, Bruno, Katia, Cappannoli, Alessandro, Cardinale, Vincenzo, Celli, Paola, Consolo, Stella, Croce, Claudia, Crocitti, Beatrice, Curreli, Mariaignazia, DEttorre, Gabriella, Daniela, De Lauri, De Lazzaro, Francesco, De Luca, Maria Lucia, Fedele, Francesco, Ferretti, Antonietta, Galardo, Gioacchino, Giannetti, Lorena, Ianni, Stefano, Imperiale, Carmela, Maestrini, Viviana, Magnanimi, Eugenia, Maldarelli, Federica, Martelli, Sabina, Mastroianni, Claudio, Messina, Teresa, Olivieri, Sandra, Pallotta, Agnese, Pattelli, Elisa, Pecorari, Filippo, Perrella, Serena, Piazzolla, Mario, Portieri, Monica, Pulcinelli, Fabio, Ratini, Fabiola, Ricci, Claudia, Santopietro, Pietro, Serrao, Alessandra, Tellan, Guglielmo, Titi, Luca, Tordiglione, Paolo, Tosi, Antonella, and Trigilia, Fausto

Subjects
medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), medicine.drug_class, viruses, low‐molecular‐weight heparin, thrombin, COVID‐19, Low molecular weight heparin, medicine.disease_cause, Thrombin generation, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, High doses, medicine, Coagulopathy, Respiratory system, Coronavirus, business.industry, Critically ill, virus diseases, Hematology, medicine.disease, 030220 oncology & carcinogenesis, business, 030215 immunology
Abstract

The clinical picture of the coronavirus 2 (SARS‐CoV‐2)/COVID‐19‐related acute respiratory syndrome is often associated with a coagulopathy. An elevated D‐dimer has been linked with an unfavorable prognosis in COVID‐19 patients.

Published
2020
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11. Usefulness of bronchoalveolar lavage in suspect COVID-19 repeatedly negative swab test and interstitial lung disease

Author

Vannucci, Jacopo, primary, Ruberto, Franco, additional, Diso, Daniele, additional, Galardo, Gioacchino, additional, Mastroianni, Claudio M., additional, Raponi, Giammarco, additional, Bassi, Massimiliano, additional, Ceccarelli, Giancarlo, additional, Mancone, Massimo, additional, Antonelli, Guido, additional, Venuta, Federico, additional, Pugliese, Francesco, additional, Albante, Alida, additional, Alessandri, Francesco, additional, Amore, Davide, additional, Anile, Marco, additional, Antognoli, Maria Gloria, additional, Morselli, Fabio Araimo, additional, Auricchio, Daniela, additional, Bianco, Martina, additional, Bilotta, Federico, additional, Birtolo, Lucia Ilaria, additional, Brisciani, Matteo, additional, Bruno, Katia, additional, Bufi, Maurizio, additional, Cagnetti, Sara, additional, Calzecchi, Elena, additional, Cappannoli, Alessandro, additional, Carillo, Carolina, additional, Casaretti, Romina, additional, Catalano, Carlo, additional, Celli, Paola, additional, Consolo, Stella, additional, Croce, Claudia, additional, Crocitti, Beatrice, additional, Cuscianna, Enrica, additional, D’Agostino, Federica Gilda, additional, Giacomo, Tiziano De, additional, Lauri, Daniela De, additional, Lazzaro, Francesco De, additional, Del Monte, Maurizio, additional, D’Ettorre, Gabriella, additional, Di Bella, Valerio, additional, Fedele, Francesco, additional, Gentile, Massimo, additional, Giordano, Giovanni, additional, Ianni, Stefano, additional, Imperiale, Carmela, additional, Infusino, Fabio, additional, Loiacono, Cinzia, additional, Maestrini, Viviana, additional, Magnanimi, Eugenia, additional, Maldarelli, Federica, additional, Mantovani, Sara, additional, Martelli, Sabina, additional, Messercola, Paolo, additional, Messina, Teresa, additional, Mottola, Emilia, additional, Pati, Valeria, additional, Pattelli, Elisa, additional, Pecorari, Filippo, additional, Pecoraro, Ylenia, additional, Perrella, Serena Maria, additional, Piazzolla, Mario, additional, Pietropaolo, Valeria, additional, Poggi, Camilla, additional, Portieri, Monica, additional, Ratini, Fabiola, additional, Ricci, Claudia, additional, Ricci, Paolo, additional, Rumori, Mario, additional, Russo, Gianluca, additional, Santopietro, Pietro, additional, Tellan, Guglielmo, additional, Titi, Luca, additional, Tordiglione, Paolo, additional, Tosi, Antonella, additional, Tosti, Silvia, additional, Trigilia, Fausto, additional, Turriziani, Ombretta, additional, Vaccaro, Paola, additional, Verduci, Noemi, additional, and Vivino, Gabriella, additional

Published
2020
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15. Perceptual Experience in Learning to Read

Author

Fogliani-Messina, Teresa M. and Fogliani, Anna M.

Abstract

A group of 24 children (12 boys and 12 girls) aged 10 yr. was given the Children's Embedded Figures Test and a Reading Ability Test on Comprehension, Accuracy, and Speed. Only the correlation of CEFT and Accuracy scores was statistically significant, while that for CEFT and Comprehension scores fell just short of significance, and that for CEFT and Speed was nonsignificant. Data are discussed in terms of more holistic and more articulated processes in learning to read, respectively, as adopted by more field-dependent and more field-independent subjects.

Published
1984
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16. Interhemispheric Transfer of Visual Information in Schizophrenics

Author

Fogliani, Anna M., Parisi, Riccardo, Fogliani-Messina, Teresa M., and Rapisarda, Vincenzo

Abstract

Groups of 12 male schizophrenic inpatients and 12 normal controls of the same age, sex, and schooling underwent a tachistoscopic test. Each subject was shown an alphabetical letter which he subsequently had to recognize among various other alphabetical letters also shown tachistoscopically. The visual hemifields of the two displays were ipsilateral and crossed. Relative to the normal group the schizophrenics showed higher perceptual thresholds, lower over-all mean performance, and greater lateralization. The results are discussed in terms of rigidly and poorly integrated systems of analysis of information between one hemisphere and the other for schizophrenic patients.

Published
1985
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17. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe M. Sangiorgi, Mariangela V. Puci, Allegra R. Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco M. Fiore, Armando Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Piero Modugno, Maurizio Maiorano, Umberto M. Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni M. Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio S. Tolva, Ilenia D’Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D’Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio M. Oddi, Alberto M. Settembrini, Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe M., Puci, Mariangela V., Martelli, Allegra R., Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Di Pinto, Luca Calia Di, Fiore, Franco M., Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massara, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto M., Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni M., Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaó, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio S., D’Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D’Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gian Franco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio M., and Settembrini, Alberto M.

Subjects
chronic limb-threatening ischemia, age, limb salvage, outcome, sex, Medicine (miscellaneous), Settore MED/09
Abstract

Background: Identifying sex-related differences/variables associated with 30 day/1 year mortality in patients with chronic limb-threatening ischemia (CLTI). Methods: Multicenter/retrospective/observational study. A database was sent to all the Italian vascular surgeries to collect all the patients operated on for CLTI in 2019. Acute lower-limb ischemia and neuropathic-diabetic foot are not included. Follow-up: One year. Data on demographics/comorbidities, treatments/outcomes, and 30 day/1 year mortality were investigated. Results: Information on 2399 cases (69.8% men) from 36/143 (25.2%) centers. Median (IQR) age: 73 (66–80) and 79 (71–85) years for men/women, respectively (p < 0.0001). Women were more likely to be over 75 (63.2% vs. 40.1%, p = 0.0001). More men smokers (73.7% vs. 42.2%, p < 0.0001), are on hemodialysis (10.1% vs. 6.7%, p = 0.006), affected by diabetes (61.9% vs. 52.8%, p < 0.0001), dyslipidemia (69.3% vs. 61.3%, p < 0.0001), hypertension (91.8% vs. 88.5%, p = 0.011), coronaropathy (43.9% vs. 29.4%, p < 0.0001), bronchopneumopathy (37.1% vs. 25.6%, p < 0.0001), underwent more open/hybrid surgeries (37.9% vs. 28.8%, p < 0.0001), and minor amputations (22% vs. 13.7%, p < 0.0001). More women underwent endovascular revascularizations (61.6% vs. 55.2%, p = 0.004), major amputations (9.6% vs. 6.9%, p = 0.024), and obtained limb-salvage if with limited gangrene (50.8% vs. 44.9%, p = 0.017). Age > 75 (HR = 3.63, p = 0.003) is associated with 30 day mortality. Age > 75 (HR = 2.14, p < 0.0001), nephropathy (HR = 1.54, p < 0.0001), coronaropathy (HR = 1.26, p = 0.036), and infection/necrosis of the foot (dry, HR = 1.42, p = 0.040; wet, HR = 2.04, p < 0.0001) are associated with 1 year mortality. No sex-linked difference in mortality statistics. Conclusion: Women exhibit fewer comorbidities but are struck by CLTI when over 75, a factor associated with short- and mid-term mortality, explaining why mortality does not statistically differ between the sexes.

Published
2023

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